Total number of protein in "GO:0006898" GO term: 105
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADM | ADM | P35318 | Pro-adrenomedullin | chr11 | GO:0006898 | Not Cancer Driver | No | 20 | 0.108 | 113 | 13 | 0.115 | 0 |
| ADRB2 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | GO:0006898 | Not Cancer Driver | No | 52 | 0.126 | 35 | 4 | 0.114 | 0 |
| ADRB3 | ADRB3 | P13945 | Beta-3 adrenergic receptor | chr8 | GO:0006898 | Not Cancer Driver | No | 40 | 0.098 | 44 | 6 | 0.136 | 0 |
| AMN | AMN | Q9BXJ7 | Protein amnionless | chr14 | GO:0006898 | Not Cancer Driver | No | 27 | 0.06 | 6 | 0 | 0.0 | 3 |
| AP1G1_ENST00000569748 | AP1G1 | O43747 | AP-1 complex subunit gamma-1 | chr16 | GO:0006898 | Not Cancer Driver | No | 111 | 0.135 | 144 | 22 | 0.153 | 0 |
| AP1G2_ENST00000397120 | AP1G2 | O75843 | AP-1 complex subunit gamma-like 2 | chr14 | GO:0006898 | Not Cancer Driver | No | 108 | 0.138 | 110 | 10 | 0.091 | 0 |
| AP1S1 | AP1S1 | P61966 | AP-1 complex subunit sigma-1A | chr7 | GO:0006898 | Not Cancer Driver | No | 21 | 0.133 | 0 | 0 | 0.0 | 0 |
| AP2A1 | AP2A1 | O95782 | AP-2 complex subunit alpha-1 | chr19 | GO:0006898 | Not Cancer Driver | No | 95 | 0.097 | 188 | 12 | 0.064 | 0 |
| AP2A2_ENST00000448903 | AP2A2 | O94973 | AP-2 complex subunit alpha-2 | chr11 | GO:0006898 | Not Cancer Driver | No | 100 | 0.106 | 145 | 12 | 0.083 | 0 |
| AP4E1 | AP4E1 | Q9UPM8 | AP-4 complex subunit epsilon-1 | chr15 | GO:0006898 | Not Cancer Driver | No | 130 | 0.114 | 148 | 28 | 0.189 | 2 |
| APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0006898 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
| ARHGAP27 | ARHGAP27 | Q6ZUM4 | Rho GTPase-activating protein 27 | chr17 | GO:0006898 | Not Cancer Driver | No | 91 | 0.102 | 516 | 57 | 0.11 | 0 |
| ARR3 | ARR3 | P36575 | Arrestin-C | chrX | GO:0006898 | Not Cancer Driver | No | 52 | 0.134 | 63 | 7 | 0.111 | 0 |
| ARRB1 | ARRB1 | P49407 | Beta-arrestin-1 | chr11 | GO:0006898 | Not Cancer Driver | No | 49 | 0.117 | 154 | 13 | 0.084 | 0 |
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | GO:0006898 | Not Cancer Driver | No | 46 | 0.112 | 122 | 22 | 0.18 | 0 |
| ASGR1 | ASGR1 | P07306 | Asialoglycoprotein receptor 1 | chr17 | GO:0006898 | Not Cancer Driver | No | 23 | 0.079 | 95 | 5 | 0.053 | 0 |
| CACNG2 | CACNG2 | Q9Y698 | Voltage-dependent calcium channel gamma-2 subunit | chr22 | GO:0006898 | Not Cancer Driver | No | 57 | 0.176 | 90 | 16 | 0.178 | 1 |
| CACNG3 | CACNG3 | O60359 | Voltage-dependent calcium channel gamma-3 subunit | chr16 | GO:0006898 | Not Cancer Driver | No | 126 | 0.4 | 69 | 37 | 0.536 | 0 |
| CACNG4 | CACNG4 | Q9UBN1 | Voltage-dependent calcium channel gamma-4 subunit | chr17 | GO:0006898 | Not Cancer Driver | No | 51 | 0.156 | 71 | 17 | 0.239 | 0 |
| CACNG5_ENST00000307139 | CACNG5 | Q9UF02 | Voltage-dependent calcium channel gamma-5 subunit | chr17 | GO:0006898 | Not Cancer Driver | No | 77 | 0.28 | 1 | 0 | 0.0 | 0 |
| CACNG7 | CACNG7 | P62955 | Voltage-dependent calcium channel gamma-7 subunit | chr19 | GO:0006898 | Not Cancer Driver | No | 99 | 0.36 | 9 | 1 | 0.111 | 0 |
| CACNG8 | CACNG8 | Q8WXS5 | Voltage-dependent calcium channel gamma-8 subunit | chr19 | GO:0006898 | Not Cancer Driver | No | 47 | 0.111 | 205 | 15 | 0.073 | 0 |
| CALY | CALY | Q9NYX4 | Neuron-specific vesicular protein calcyon | chr10 | GO:0006898 | Not Cancer Driver | No | 8 | 0.037 | 133 | 5 | 0.038 | 0 |
| CAP1_ENST00000372805 | CAP1 | Q01518 | Adenylyl cyclase-associated protein 1 | chr1 | GO:0006898 | Not Cancer Driver | No | 70 | 0.147 | 156 | 31 | 0.199 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0006898 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CAV2 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0006898 | Not Cancer Driver | No | 20 | 0.123 | 5 | 2 | 0.4 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0006898 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CD14 | CD14 | P08571 | Monocyte differentiation antigen CD14 | chr5 | GO:0006898 | Not Cancer Driver | No | 42 | 0.112 | 60 | 5 | 0.083 | 0 |
| CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0006898 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
| CEACAM1 | CEACAM1 | P13688 | Carcinoembryonic antigen-related cell adhesion molecule 1 | chr19 | GO:0006898 | Not Cancer Driver | No | 64 | 0.122 | 241 | 25 | 0.104 | 0 |
| CLEC9A | CLEC9A | Q6UXN8 | C-type lectin domain family 9 member A | chr12 | GO:0006898 | Not Cancer Driver | No | 62 | 0.257 | 7 | 1 | 0.143 | 0 |
| CLN3_ENST00000636147 | CLN3 | Q13286 | Battenin | chr16 | GO:0006898 | Not Cancer Driver | No | 58 | 0.132 | 69 | 10 | 0.145 | 9 |
| CLTCL1 | CLTCL1 | P53675 | Clathrin heavy chain 2 | chr22 | GO:0006898 | Census, Compendium | Yes | 210 | 0.128 | 10 | 1 | 0.1 | 0 |
| CLTC_ENST00000269122 | CLTC | Q00610 | Clathrin heavy chain 1 | chr17 | GO:0006898 | Census, Compendium | Yes | 190 | 0.113 | 71 | 6 | 0.085 | 1 |
| CTSL | CTSL | P07711 | Procathepsin L | chr9 | GO:0006898 | Not Cancer Driver | No | 47 | 0.141 | 34 | 4 | 0.118 | 0 |
| CTTN_ENST00000301843 | CTTN | Q14247 | Src substrate cortactin | chr11 | GO:0006898 | Not Cancer Driver | No | 78 | 0.142 | 465 | 56 | 0.12 | 0 |
| CUBN | CUBN | O60494 | Cubilin | chr10 | GO:0006898 | Not Cancer Driver | No | 709 | 0.196 | 272 | 54 | 0.199 | 2 |
| DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0006898 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
| DBNL_ENST00000448521 | DBNL | Q9UJU6 | Drebrin-like protein | chr7 | GO:0006898 | Not Cancer Driver | No | 46 | 0.107 | 304 | 31 | 0.102 | 0 |
| DNAJC13 | DNAJC13 | O75165 | DnaJ homolog subfamily C member 13 | chr3 | GO:0006898 | Not Cancer Driver | No | 276 | 0.123 | 141 | 17 | 0.121 | 0 |
| DNM1 | DNM1 | Q05193 | Dynamin-1 | chr9 | GO:0006898 | Not Cancer Driver | No | 98 | 0.113 | 280 | 23 | 0.082 | 4 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | GO:0006898 | Census | Yes | 138 | 0.159 | 270 | 43 | 0.159 | 22 |
| DNM3_ENST00000355305 | DNM3 | Q9UQ16 | Dynamin-3 | chr1 | GO:0006898 | Not Cancer Driver | No | 166 | 0.191 | 257 | 45 | 0.175 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0006898 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0006898 | Not Cancer Driver | No | 88 | 0.22 | 45 | 17 | 0.378 | 0 |
| EPS15 | EPS15 | P42566 | Epidermal growth factor receptor substrate 15 | chr1 | GO:0006898 | Census, Compendium | Yes | 106 | 0.118 | 543 | 66 | 0.122 | 0 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0006898 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FOLR1_ENST00000393681 | FOLR1 | P15328 | Folate receptor alpha | chr11 | GO:0006898 | Not Cancer Driver | No | 41 | 0.16 | 13 | 3 | 0.231 | 0 |
| FPR2 | FPR2 | P25090 | N-formyl peptide receptor 2 | chr19 | GO:0006898 | Not Cancer Driver | No | 96 | 0.274 | 26 | 5 | 0.192 | 0 |
| GAK | GAK | O14976 | Cyclin-G-associated kinase | chr4 | GO:0006898 | Not Cancer Driver | No | 146 | 0.111 | 589 | 79 | 0.134 | 0 |
| GTF2H2_ENST00000330280 | GTF2H2 | Q13888 | General transcription factor IIH subunit 2 | chr5 | GO:0006898 | Not Cancer Driver | No | 7 | 0.018 | 43 | 1 | 0.023 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0006898 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| HSPG2 | HSPG2 | P98160 | Basement membrane-specific heparan sulfate proteoglycan core protein | chr1 | GO:0006898 | Compendium | Yes | 506 | 0.115 | 1709 | 194 | 0.114 | 1 |
| HTR1B | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | GO:0006898 | Not Cancer Driver | No | 91 | 0.233 | 33 | 15 | 0.455 | 0 |
| HTR2B | HTR2B | P41595 | 5-hydroxytryptamine receptor 2B | chr2 | GO:0006898 | Not Cancer Driver | No | 41 | 0.085 | 23 | 2 | 0.087 | 0 |
| IGF2R | IGF2R | P11717 | Cation-independent mannose-6-phosphate receptor | chr6 | GO:0006898 | Not Cancer Driver | No | 318 | 0.128 | 255 | 20 | 0.078 | 0 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0006898 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | GO:0006898 | Not Cancer Driver | No | 254 | 0.246 | 97 | 27 | 0.278 | 0 |
| ITGAM_ENST00000287497 | ITGAM | P11215 | Integrin alpha-M | chr16 | GO:0006898 | Not Cancer Driver | No | 191 | 0.166 | 133 | 12 | 0.09 | 0 |
| ITGB2_ENST00000355153 | ITGB2 | P05107 | Integrin beta-2 | chr21 | GO:0006898 | Not Cancer Driver | No | 147 | 0.191 | 59 | 9 | 0.153 | 15 |
| ITSN1 | ITSN1 | Q15811 | Intersectin-1 | chr21 | GO:0006898 | Not Cancer Driver | No | 214 | 0.124 | 797 | 107 | 0.134 | 0 |
| ITSN2 | ITSN2 | Q9NZM3 | Intersectin-2 | chr2 | GO:0006898 | Not Cancer Driver | No | 207 | 0.122 | 680 | 92 | 0.135 | 0 |
| LDLR | LDLR | P01130 | Low-density lipoprotein receptor | chr19 | GO:0006898 | Not Cancer Driver | No | 119 | 0.138 | 63 | 3 | 0.048 | 104 |
| LDLRAD3 | LDLRAD3 | Q86YD5 | Low-density lipoprotein receptor class A domain-containing protein 3 | chr11 | GO:0006898 | Not Cancer Driver | No | 46 | 0.133 | 123 | 14 | 0.114 | 0 |
| LDLRAP1 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0006898 | Not Cancer Driver | No | 36 | 0.117 | 119 | 17 | 0.143 | 1 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | GO:0006898 | Not Cancer Driver | No | 57 | 0.117 | 4 | 0 | 0.0 | 0 |
| LMBRD1 | LMBRD1 | Q9NUN5 | Lysosomal cobalamin transport escort protein LMBD1 | chr6 | GO:0006898 | Not Cancer Driver | No | 90 | 0.167 | 31 | 3 | 0.097 | 0 |
| LRP1 | LRP1 | Q07954 | Prolow-density lipoprotein receptor-related protein 1 | chr12 | GO:0006898 | Not Cancer Driver | No | 664 | 0.146 | 317 | 52 | 0.164 | 1 |
| LRP1B | LRP1B | Q9NZR2 | Low-density lipoprotein receptor-related protein 1B | chr2 | GO:0006898 | Census, Compendium | Yes | 1727 | 0.376 | 177 | 78 | 0.441 | 0 |
| LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0006898 | Not Cancer Driver | No | 998 | 0.214 | 209 | 40 | 0.191 | 1 |
| LRP3 | LRP3 | O75074 | Low-density lipoprotein receptor-related protein 3 | chr19 | GO:0006898 | Not Cancer Driver | No | 88 | 0.114 | 214 | 20 | 0.093 | 0 |
| LRP6 | LRP6 | O75581 | Low-density lipoprotein receptor-related protein 6 | chr12 | GO:0006898 | Not Cancer Driver | No | 206 | 0.128 | 255 | 30 | 0.118 | 5 |
| M6PR | M6PR | P20645 | Cation-dependent mannose-6-phosphate receptor | chr12 | GO:0006898 | Not Cancer Driver | No | 16 | 0.058 | 35 | 4 | 0.114 | 0 |
| MARCO | MARCO | Q9UEW3 | Macrophage receptor MARCO | chr2 | GO:0006898 | Not Cancer Driver | No | 180 | 0.346 | 323 | 125 | 0.387 | 0 |
| MICALL1 | MICALL1 | Q8N3F8 | MICAL-like protein 1 | chr22 | GO:0006898 | Not Cancer Driver | No | 90 | 0.104 | 630 | 72 | 0.114 | 0 |
| MRC1 | MRC1 | P22897 | Macrophage mannose receptor 1 | chr10 | GO:0006898 | Not Cancer Driver | No | 40 | 0.027 | 126 | 1 | 0.008 | 0 |
| MSR1 | MSR1 | P21757 | Macrophage scavenger receptor types I and II | chr8 | GO:0006898 | Not Cancer Driver | No | 167 | 0.37 | 241 | 106 | 0.44 | 0 |
| NLGN3 | NLGN3 | Q9NZ94 | Neuroligin-3 | chrX | GO:0006898 | Not Cancer Driver | No | 158 | 0.186 | 257 | 54 | 0.21 | 2 |
| PDLIM7 | PDLIM7 | Q9NR12 | PDZ and LIM domain protein 7 | chr5 | GO:0006898 | Not Cancer Driver | No | 48 | 0.105 | 244 | 20 | 0.082 | 0 |
| PI4KB_ENST00000368873 | PI4KB | Q9UBF8 | Phosphatidylinositol 4-kinase beta | chr1 | GO:0006898 | Not Cancer Driver | No | 93 | 0.114 | 311 | 34 | 0.109 | 0 |
| PICALM | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0006898 | Census | Yes | 89 | 0.137 | 320 | 42 | 0.131 | 0 |
| PIKFYVE | PIKFYVE | Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinase | chr2 | GO:0006898 | Not Cancer Driver | No | 278 | 0.133 | 848 | 101 | 0.119 | 1 |
| PLA2R1 | PLA2R1 | Q13018 | Secretory phospholipase A2 receptor | chr2 | GO:0006898 | Not Cancer Driver | No | 202 | 0.138 | 39 | 2 | 0.051 | 0 |
| PPT1 | PPT1 | P50897 | Palmitoyl-protein thioesterase 1 | chr1 | GO:0006898 | Not Cancer Driver | No | 37 | 0.121 | 0 | 0 | 0.0 | 23 |
| RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | GO:0006898 | Not Cancer Driver | No | 32 | 0.149 | 65 | 15 | 0.231 | 0 |
| RABEPK | RABEPK | Q7Z6M1 | Rab9 effector protein with kelch motifs | chr9 | GO:0006898 | Not Cancer Driver | No | 54 | 0.145 | 161 | 24 | 0.149 | 0 |
| REPS1 | REPS1 | Q96D71 | RalBP1-associated Eps domain-containing protein 1 | chr6 | GO:0006898 | Not Cancer Driver | No | 89 | 0.112 | 606 | 70 | 0.116 | 2 |
| SAG | SAG | P10523 | S-arrestin | chr2 | GO:0006898 | Not Cancer Driver | No | 70 | 0.173 | 102 | 11 | 0.108 | 0 |
| SCARB2 | SCARB2 | Q14108 | Lysosome membrane protein 2 | chr4 | GO:0006898 | Not Cancer Driver | No | 61 | 0.128 | 13 | 3 | 0.231 | 1 |
| SCARF1 | SCARF1 | Q14162 | Scavenger receptor class F member 1 | chr17 | GO:0006898 | Not Cancer Driver | No | 90 | 0.108 | 340 | 61 | 0.179 | 0 |
| SCYL2_ENST00000360820 | SCYL2 | Q6P3W7 | SCY1-like protein 2 | chr12 | GO:0006898 | Not Cancer Driver | No | 103 | 0.111 | 328 | 29 | 0.088 | 0 |
| SFTPD | SFTPD | P35247 | Pulmonary surfactant-associated protein D | chr10 | GO:0006898 | Not Cancer Driver | No | 66 | 0.176 | 274 | 53 | 0.193 | 0 |
| SIGLEC1 | SIGLEC1 | Q9BZZ2 | Sialoadhesin | chr20 | GO:0006898 | Not Cancer Driver | No | 307 | 0.18 | 314 | 68 | 0.217 | 0 |
| SNAP25 | SNAP25 | P60880 | Synaptosomal-associated protein 25 | chr20 | GO:0006898 | Not Cancer Driver | No | 61 | 0.296 | 176 | 49 | 0.278 | 1 |
| SNX17 | SNX17 | Q15036 | Sorting nexin-17 | chr2 | GO:0006898 | Not Cancer Driver | No | 55 | 0.117 | 118 | 10 | 0.085 | 0 |
| SNX9 | SNX9 | Q9Y5X1 | Sorting nexin-9 | chr6 | GO:0006898 | Not Cancer Driver | No | 71 | 0.119 | 231 | 23 | 0.1 | 0 |
| SORL1 | SORL1 | Q92673 | Sortilin-related receptor | chr11 | GO:0006898 | Not Cancer Driver | No | 374 | 0.169 | 87 | 10 | 0.115 | 0 |
| STAB1 | STAB1 | Q9NY15 | Stabilin-1 | chr3 | GO:0006898 | Not Cancer Driver | No | 341 | 0.133 | 91 | 13 | 0.143 | 0 |
| STAB2 | STAB2 | Q8WWQ8 | Stabilin-2 | chr12 | GO:0006898 | Not Cancer Driver | No | 482 | 0.189 | 101 | 16 | 0.158 | 0 |
| TFR2_ENST00000223051 | TFR2 | Q9UP52 | Transferrin receptor protein 2 | chr7 | GO:0006898 | Not Cancer Driver | No | 94 | 0.117 | 168 | 20 | 0.119 | 3 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0006898 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| TMEM108 | TMEM108 | Q6UXF1 | Transmembrane protein 108 | chr3 | GO:0006898 | Not Cancer Driver | No | 101 | 0.176 | 458 | 89 | 0.194 | 0 |
| TPCN2 | TPCN2 | Q8NHX9 | Two pore channel protein 2 | chr11 | GO:0006898 | Not Cancer Driver | No | 73 | 0.097 | 16 | 0 | 0.0 | 0 |
| VLDLR | VLDLR | P98155 | Very low-density lipoprotein receptor | chr9 | GO:0006898 | Not Cancer Driver | No | 90 | 0.103 | 55 | 3 | 0.055 | 0 |
| WASF1_ENST00000392586 | WASF1 | Q92558 | Wiskott-Aldrich syndrome protein family member 1 | chr6 | GO:0006898 | Not Cancer Driver | No | 63 | 0.113 | 445 | 49 | 0.11 | 0 |