Total number of protein in "GO:0006694" GO term: 74
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCB11 | ABCB11 | O95342 | Bile salt export pump | chr2 | GO:0006694 | Not Cancer Driver | No | 233 | 0.176 | 124 | 24 | 0.194 | 21 |
| ABCD3 | ABCD3 | P28288 | ATP-binding cassette sub-family D member 3 | chr1 | GO:0006694 | Not Cancer Driver | No | 75 | 0.114 | 21 | 2 | 0.095 | 0 |
| ACBD3 | ACBD3 | Q9H3P7 | Golgi resident protein GCP60 | chr1 | GO:0006694 | Not Cancer Driver | No | 59 | 0.112 | 350 | 40 | 0.114 | 0 |
| ACOT8 | ACOT8 | O14734 | Acyl-coenzyme A thioesterase 8 | chr20 | GO:0006694 | Not Cancer Driver | No | 43 | 0.135 | 52 | 7 | 0.135 | 0 |
| AKR1B1 | AKR1B1 | P15121 | Aldo-keto reductase family 1 member B1 | chr7 | GO:0006694 | Not Cancer Driver | No | 52 | 0.165 | 19 | 1 | 0.053 | 0 |
| AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0006694 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
| AKR1C4 | AKR1C4 | P17516 | Aldo-keto reductase family 1 member C4 | chr10 | GO:0006694 | Not Cancer Driver | No | 78 | 0.241 | 9 | 3 | 0.333 | 0 |
| AKR1D1 | AKR1D1 | P51857 | Aldo-keto reductase family 1 member D1 | chr7 | GO:0006694 | Not Cancer Driver | No | 89 | 0.273 | 15 | 3 | 0.2 | 5 |
| AMACR_ENST00000335606 | AMACR | Q9UHK6 | Alpha-methylacyl-CoA racemase | chr5 | GO:0006694 | Not Cancer Driver | No | 56 | 0.147 | 38 | 8 | 0.211 | 3 |
| BAAT_ENST00000395051 | BAAT | Q14032 | Bile acid-CoA:amino acid N-acyltransferase | chr9 | GO:0006694 | Not Cancer Driver | No | 88 | 0.211 | 10 | 4 | 0.4 | 1 |
| CACNA1H | CACNA1H | O95180 | Voltage-dependent T-type calcium channel subunit alpha-1H | chr16 | GO:0006694 | Not Cancer Driver | No | 323 | 0.137 | 1045 | 141 | 0.135 | 18 |
| CRH | CRH | P06850 | Corticoliberin | chr8 | GO:0006694 | Not Cancer Driver | No | 10 | 0.051 | 131 | 9 | 0.069 | 0 |
| CYP11A1 | CYP11A1 | P05108 | Cholesterol side-chain cleavage enzyme, mitochondrial | chr15 | GO:0006694 | Not Cancer Driver | No | 92 | 0.177 | 27 | 6 | 0.222 | 6 |
| CYP11B1 | CYP11B1 | P15538 | Cytochrome P450 11B1, mitochondrial | chr8 | GO:0006694 | Not Cancer Driver | No | 177 | 0.352 | 7 | 1 | 0.143 | 50 |
| CYP11B2 | CYP11B2 | P19099 | Cytochrome P450 11B2, mitochondrial | chr8 | GO:0006694 | Not Cancer Driver | No | 148 | 0.294 | 6 | 0 | 0.0 | 6 |
| CYP17A1 | CYP17A1 | P05093 | Steroid 17-alpha-hydroxylase/17,20 lyase | chr10 | GO:0006694 | Not Cancer Driver | No | 64 | 0.126 | 34 | 2 | 0.059 | 26 |
| CYP19A1_ENST00000396404 | CYP19A1 | P11511 | Aromatase | chr15 | GO:0006694 | Not Cancer Driver | No | 91 | 0.181 | 2 | 1 | 0.5 | 5 |
| CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0006694 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
| CYP21A2_ENST00000643666 | CYP21A2 | P08686 | Steroid 21-hydroxylase | chr6 | GO:0006694 | Not Cancer Driver | No | 70 | 0.142 | 49 | 16 | 0.327 | 66 |
| CYP27A1 | CYP27A1 | Q02318 | Sterol 26-hydroxylase, mitochondrial | chr2 | GO:0006694 | Not Cancer Driver | No | 69 | 0.13 | 47 | 11 | 0.234 | 7 |
| CYP27B1 | CYP27B1 | O15528 | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | chr12 | GO:0006694 | Not Cancer Driver | No | 71 | 0.14 | 79 | 13 | 0.165 | 18 |
| CYP2R1 | CYP2R1 | Q6VVX0 | Vitamin D 25-hydroxylase | chr11 | GO:0006694 | Not Cancer Driver | No | 53 | 0.106 | 5 | 1 | 0.2 | 1 |
| CYP39A1 | CYP39A1 | Q9NYL5 | 24-hydroxycholesterol 7-alpha-hydroxylase | chr6 | GO:0006694 | Not Cancer Driver | No | 61 | 0.13 | 3 | 0 | 0.0 | 0 |
| CYP3A4 | CYP3A4 | P08684 | Cytochrome P450 3A4 | chr7 | GO:0006694 | Not Cancer Driver | No | 91 | 0.181 | 22 | 2 | 0.091 | 1 |
| CYP3A7 | CYP3A7 | P24462 | Cytochrome P450 3A7 | chr7 | GO:0006694 | Not Cancer Driver | No | 91 | 0.181 | 17 | 6 | 0.353 | 0 |
| CYP46A1 | CYP46A1 | Q9Y6A2 | Cholesterol 24-hydroxylase | chr14 | GO:0006694 | Not Cancer Driver | No | 92 | 0.184 | 23 | 4 | 0.174 | 0 |
| CYP51A1 | CYP51A1 | Q16850 | Lanosterol 14-alpha demethylase | chr7 | GO:0006694 | Not Cancer Driver | No | 49 | 0.096 | 7 | 2 | 0.286 | 0 |
| CYP7A1 | CYP7A1 | P22680 | Cytochrome P450 7A1 | chr8 | GO:0006694 | Not Cancer Driver | No | 109 | 0.216 | 48 | 8 | 0.167 | 0 |
| CYP7B1 | CYP7B1 | O75881 | Cytochrome P450 7B1 | chr8 | GO:0006694 | Not Cancer Driver | No | 133 | 0.263 | 0 | 0 | 0.0 | 11 |
| CYP8B1 | CYP8B1 | Q9UNU6 | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase | chr3 | GO:0006694 | Not Cancer Driver | No | 91 | 0.182 | 5 | 1 | 0.2 | 0 |
| DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | GO:0006694 | Not Cancer Driver | No | 55 | 0.107 | 0 | 0 | 0.0 | 6 |
| DHCR7 | DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | chr11 | GO:0006694 | Not Cancer Driver | No | 85 | 0.179 | 7 | 1 | 0.143 | 53 |
| EBP | EBP | Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | chrX | GO:0006694 | Not Cancer Driver | No | 30 | 0.13 | 9 | 0 | 0.0 | 9 |
| FDFT1_ENST00000615631 | FDFT1 | P37268 | Squalene synthase | chr8 | GO:0006694 | Not Cancer Driver | No | 39 | 0.094 | 19 | 0 | 0.0 | 0 |
| FDX1 | FDX1 | P10109 | Adrenodoxin, mitochondrial | chr11 | GO:0006694 | Not Cancer Driver | No | 12 | 0.065 | 61 | 2 | 0.033 | 0 |
| FDXR_ENST00000293195 | FDXR | P22570 | NADPH:adrenodoxin oxidoreductase, mitochondrial | chr17 | GO:0006694 | Not Cancer Driver | No | 68 | 0.138 | 102 | 14 | 0.137 | 4 |
| FSHB_ENST00000254122 | FSHB | P01225 | Follitropin subunit beta | chr11 | GO:0006694 | Not Cancer Driver | No | 31 | 0.24 | 0 | 0 | 0.0 | 1 |
| HINT2 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | GO:0006694 | Not Cancer Driver | No | 10 | 0.061 | 29 | 2 | 0.069 | 0 |
| HSD17B10 | HSD17B10 | Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | chrX | GO:0006694 | Not Cancer Driver | No | 27 | 0.103 | 15 | 3 | 0.2 | 11 |
| HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | GO:0006694 | Not Cancer Driver | No | 28 | 0.093 | 3 | 0 | 0.0 | 0 |
| HSD17B12 | HSD17B12 | Q53GQ0 | Very-long-chain 3-oxoacyl-CoA reductase | chr11 | GO:0006694 | Not Cancer Driver | No | 32 | 0.103 | 9 | 0 | 0.0 | 0 |
| HSD17B1_ENST00000585807 | HSD17B1 | P14061 | 17-beta-hydroxysteroid dehydrogenase type 1 | chr17 | GO:0006694 | Not Cancer Driver | No | 48 | 0.146 | 59 | 28 | 0.475 | 0 |
| HSD17B2 | HSD17B2 | P37059 | 17-beta-hydroxysteroid dehydrogenase type 2 | chr16 | GO:0006694 | Not Cancer Driver | No | 55 | 0.142 | 6 | 1 | 0.167 | 0 |
| HSD17B3 | HSD17B3 | P37058 | 17-beta-hydroxysteroid dehydrogenase type 3 | chr9 | GO:0006694 | Not Cancer Driver | No | 42 | 0.135 | 0 | 0 | 0.0 | 15 |
| HSD17B6_ENST00000322165 | HSD17B6 | O14756 | 17-beta-hydroxysteroid dehydrogenase type 6 | chr12 | GO:0006694 | Not Cancer Driver | No | 35 | 0.11 | 5 | 1 | 0.2 | 0 |
| HSD17B7 | HSD17B7 | P56937 | 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 | chr1 | GO:0006694 | Not Cancer Driver | No | 33 | 0.097 | 0 | 0 | 0.0 | 0 |
| HSD17B8 | HSD17B8 | Q92506 | (3R)-3-hydroxyacyl-CoA dehydrogenase | chr6 | GO:0006694 | Not Cancer Driver | No | 20 | 0.077 | 26 | 1 | 0.038 | 0 |
| HSD3B1 | HSD3B1 | P14060 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 | chr1 | GO:0006694 | Not Cancer Driver | No | 69 | 0.185 | 25 | 3 | 0.12 | 0 |
| HSD3B2_ENST00000369416 | HSD3B2 | P26439 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 | chr1 | GO:0006694 | Not Cancer Driver | No | 83 | 0.223 | 24 | 9 | 0.375 | 28 |
| HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | GO:0006694 | Not Cancer Driver | No | 43 | 0.117 | 27 | 5 | 0.185 | 2 |
| LHB | LHB | P01229 | Lutropin subunit beta | chr19 | GO:0006694 | Not Cancer Driver | No | 20 | 0.142 | 0 | 0 | 0.0 | 1 |
| LSS | LSS | P48449 | Lanosterol synthase | chr21 | GO:0006694 | Not Cancer Driver | No | 85 | 0.116 | 31 | 5 | 0.161 | 6 |
| MED1 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0006694 | Not Cancer Driver | No | 162 | 0.102 | 1104 | 117 | 0.106 | 0 |
| OSBP | OSBP | P22059 | Oxysterol-binding protein 1 | chr11 | GO:0006694 | Not Cancer Driver | No | 83 | 0.103 | 386 | 39 | 0.101 | 0 |
| OSBPL1A | OSBPL1A | Q9BXW6 | Oxysterol-binding protein-related protein 1 | chr18 | GO:0006694 | Not Cancer Driver | No | 110 | 0.116 | 314 | 27 | 0.086 | 0 |
| OSBPL2_ENST00000643981 | OSBPL2 | Q9H1P3 | Oxysterol-binding protein-related protein 2 | chr20 | GO:0006694 | Not Cancer Driver | No | 57 | 0.119 | 173 | 18 | 0.104 | 0 |
| OSBPL3 | OSBPL3 | Q9H4L5 | Oxysterol-binding protein-related protein 3 | chr7 | GO:0006694 | Not Cancer Driver | No | 114 | 0.129 | 324 | 44 | 0.136 | 0 |
| OSBPL6_ENST00000190611 | OSBPL6 | Q9BZF3 | Oxysterol-binding protein-related protein 6 | chr2 | GO:0006694 | Not Cancer Driver | No | 167 | 0.179 | 365 | 72 | 0.197 | 0 |
| OSBPL7_ENST00000392507 | OSBPL7 | Q9BZF2 | Oxysterol-binding protein-related protein 7 | chr17 | GO:0006694 | Not Cancer Driver | No | 99 | 0.118 | 395 | 44 | 0.111 | 0 |
| OSBPL9_ENST00000428468 | OSBPL9 | Q96SU4 | Oxysterol-binding protein-related protein 9 | chr1 | GO:0006694 | Not Cancer Driver | No | 90 | 0.122 | 237 | 32 | 0.135 | 0 |
| PBX1 | PBX1 | P40424 | Pre-B-cell leukemia transcription factor 1 | chr1 | GO:0006694 | Census | Yes | 82 | 0.191 | 290 | 57 | 0.197 | 0 |
| PRLR | PRLR | P16471 | Prolactin receptor | chr5 | GO:0006694 | Not Cancer Driver | No | 154 | 0.248 | 282 | 70 | 0.248 | 2 |
| SC5D_ENST00000392789 | SC5D | O75845 | Lathosterol oxidase | chr11 | GO:0006694 | Not Cancer Driver | No | 43 | 0.144 | 21 | 3 | 0.143 | 3 |
| SCP2 | SCP2 | P22307 | Sterol carrier protein 2 | chr1 | GO:0006694 | Not Cancer Driver | No | 59 | 0.108 | 45 | 2 | 0.044 | 0 |
| SCP2D1 | SCP2D1 | Q9UJQ7 | SCP2 sterol-binding domain-containing protein 1 | chr20 | GO:0006694 | Not Cancer Driver | No | 38 | 0.244 | 21 | 5 | 0.238 | 0 |
| SDR42E1 | SDR42E1 | Q8WUS8 | Short-chain dehydrogenase/reductase family 42E member 1 | chr16 | GO:0006694 | Not Cancer Driver | No | 63 | 0.16 | 26 | 6 | 0.231 | 0 |
| SLC27A2 | SLC27A2 | O14975 | Very long-chain acyl-CoA synthetase | chr15 | GO:0006694 | Not Cancer Driver | No | 95 | 0.153 | 4 | 0 | 0.0 | 0 |
| SLC27A5 | SLC27A5 | Q9Y2P5 | Bile acyl-CoA synthetase | chr19 | GO:0006694 | Not Cancer Driver | No | 107 | 0.155 | 7 | 2 | 0.286 | 0 |
| SRD5A1 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0006694 | Not Cancer Driver | No | 35 | 0.135 | 0 | 0 | 0.0 | 0 |
| SRD5A2 | SRD5A2 | P31213 | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | chr2 | GO:0006694 | Not Cancer Driver | No | 48 | 0.189 | 0 | 0 | 0.0 | 21 |
| SRD5A3 | SRD5A3 | Q9H8P0 | Polyprenol reductase | chr4 | GO:0006694 | Not Cancer Driver | No | 35 | 0.11 | 0 | 0 | 0.0 | 0 |
| STAR | STAR | P49675 | Steroidogenic acute regulatory protein, mitochondrial | chr8 | GO:0006694 | Not Cancer Driver | No | 45 | 0.158 | 85 | 10 | 0.118 | 7 |
| STARD3 | STARD3 | Q14849 | StAR-related lipid transfer protein 3 | chr17 | GO:0006694 | Not Cancer Driver | No | 51 | 0.115 | 34 | 6 | 0.176 | 0 |
| TSPO_ENST00000329563 | TSPO | P30536 | Translocator protein | chr22 | GO:0006694 | Not Cancer Driver | No | 5 | 0.03 | 1 | 0 | 0.0 | 0 |