Total number of protein in "GO:0006690" GO term: 90
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC1 | ABCC1 | P33527 | Multidrug resistance-associated protein 1 | chr16 | GO:0006690 | Not Cancer Driver | No | 199 | 0.13 | 123 | 22 | 0.179 | 1 |
| ABCC10 | ABCC10 | Q5T3U5 | ATP-binding cassette sub-family C member 10 | chr6 | GO:0006690 | Not Cancer Driver | No | 192 | 0.129 | 105 | 9 | 0.086 | 0 |
| ABHD12_ENST00000339157 | ABHD12 | Q8N2K0 | Lysophosphatidylserine lipase ABHD12 | chr20 | GO:0006690 | Not Cancer Driver | No | 45 | 0.113 | 8 | 1 | 0.125 | 1 |
| ABHD6 | ABHD6 | Q9BV23 | Monoacylglycerol lipase ABHD6 | chr3 | GO:0006690 | Not Cancer Driver | No | 38 | 0.113 | 11 | 2 | 0.182 | 0 |
| AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0006690 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
| ALOX12 | ALOX12 | P18054 | Polyunsaturated fatty acid lipoxygenase ALOX12 | chr17 | GO:0006690 | Not Cancer Driver | No | 73 | 0.11 | 73 | 12 | 0.164 | 0 |
| ALOX12B | ALOX12B | O75342 | Arachidonate 12-lipoxygenase, 12R-type | chr17 | GO:0006690 | Not Cancer Driver | No | 101 | 0.144 | 16 | 3 | 0.188 | 18 |
| ALOX15B | ALOX15B | O15296 | Polyunsaturated fatty acid lipoxygenase ALOX15B | chr17 | GO:0006690 | Not Cancer Driver | No | 99 | 0.146 | 62 | 12 | 0.194 | 0 |
| ALOX15_ENST00000293761 | ALOX15 | P16050 | Polyunsaturated fatty acid lipoxygenase ALOX15 | chr17 | GO:0006690 | Not Cancer Driver | No | 84 | 0.127 | 46 | 7 | 0.152 | 0 |
| ALOX5 | ALOX5 | P09917 | Polyunsaturated fatty acid 5-lipoxygenase | chr10 | GO:0006690 | Not Cancer Driver | No | 129 | 0.191 | 16 | 2 | 0.125 | 0 |
| ALOX5AP_ENST00000380490 | ALOX5AP | P20292 | Arachidonate 5-lipoxygenase-activating protein | chr13 | GO:0006690 | Not Cancer Driver | No | 17 | 0.106 | 1 | 0 | 0.0 | 0 |
| ALOXE3_ENST00000448843 | ALOXE3 | Q9BYJ1 | Hydroperoxide isomerase ALOXE3 | chr17 | GO:0006690 | Not Cancer Driver | No | 108 | 0.152 | 69 | 13 | 0.188 | 6 |
| AWAT1 | AWAT1 | Q58HT5 | Acyl-CoA wax alcohol acyltransferase 1 | chrX | GO:0006690 | Not Cancer Driver | No | 49 | 0.149 | 0 | 0 | 0.0 | 0 |
| CBR1 | CBR1 | P16152 | Carbonyl reductase [NADPH] 1 | chr21 | GO:0006690 | Not Cancer Driver | No | 27 | 0.097 | 62 | 11 | 0.177 | 0 |
| CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0006690 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
| CPA1 | CPA1 | P15085 | Carboxypeptidase A1 | chr7 | GO:0006690 | Not Cancer Driver | No | 84 | 0.2 | 5 | 1 | 0.2 | 0 |
| CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0006690 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
| CYP1A2 | CYP1A2 | P05177 | Cytochrome P450 1A2 | chr15 | GO:0006690 | Not Cancer Driver | No | 93 | 0.18 | 23 | 3 | 0.13 | 0 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0006690 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| CYP2A13 | CYP2A13 | Q16696 | Cytochrome P450 2A13 | chr19 | GO:0006690 | Not Cancer Driver | No | 122 | 0.247 | 38 | 9 | 0.237 | 0 |
| CYP2A6 | CYP2A6 | P11509 | Cytochrome P450 2A6 | chr19 | GO:0006690 | Not Cancer Driver | No | 107 | 0.217 | 40 | 10 | 0.25 | 0 |
| CYP2A7 | CYP2A7 | P20853 | Cytochrome P450 2A7 | chr19 | GO:0006690 | Not Cancer Driver | No | 95 | 0.192 | 39 | 9 | 0.231 | 0 |
| CYP2B6 | CYP2B6 | P20813 | Cytochrome P450 2B6 | chr19 | GO:0006690 | Not Cancer Driver | No | 137 | 0.279 | 39 | 13 | 0.333 | 0 |
| CYP2C18 | CYP2C18 | P33260 | Cytochrome P450 2C18 | chr10 | GO:0006690 | Not Cancer Driver | No | 114 | 0.233 | 11 | 1 | 0.091 | 0 |
| CYP2C19 | CYP2C19 | P33261 | Cytochrome P450 2C19 | chr10 | GO:0006690 | Not Cancer Driver | No | 157 | 0.32 | 32 | 12 | 0.375 | 0 |
| CYP2C8 | CYP2C8 | P10632 | Cytochrome P450 2C8 | chr10 | GO:0006690 | Census, Compendium | Yes | 113 | 0.231 | 30 | 11 | 0.367 | 0 |
| CYP2C9 | CYP2C9 | P11712 | Cytochrome P450 2C9 | chr10 | GO:0006690 | Not Cancer Driver | No | 122 | 0.249 | 36 | 14 | 0.389 | 0 |
| CYP2D6_ENST00000645361 | CYP2D6 | P10635 | Cytochrome P450 2D6 | chr22 | GO:0006690 | Not Cancer Driver | No | 76 | 0.153 | 66 | 8 | 0.121 | 0 |
| CYP2D7 | CYP2D7 | A0A087X1C5 | Putative cytochrome P450 2D7 | chr22 | GO:0006690 | Not Cancer Driver | No | 74 | 0.144 | 60 | 6 | 0.1 | 0 |
| CYP2E1_ENST00000252945 | CYP2E1 | P05181 | Cytochrome P450 2E1 | chr10 | GO:0006690 | Not Cancer Driver | No | 87 | 0.176 | 21 | 6 | 0.286 | 0 |
| CYP2F1 | CYP2F1 | P24903 | Cytochrome P450 2F1 | chr19 | GO:0006690 | Not Cancer Driver | No | 85 | 0.173 | 2 | 0 | 0.0 | 0 |
| CYP2J2 | CYP2J2 | P51589 | Cytochrome P450 2J2 | chr1 | GO:0006690 | Not Cancer Driver | No | 58 | 0.116 | 63 | 6 | 0.095 | 0 |
| CYP2S1 | CYP2S1 | Q96SQ9 | Cytochrome P450 2S1 | chr19 | GO:0006690 | Not Cancer Driver | No | 75 | 0.149 | 46 | 10 | 0.217 | 0 |
| CYP2U1 | CYP2U1 | Q7Z449 | Cytochrome P450 2U1 | chr4 | GO:0006690 | Not Cancer Driver | No | 37 | 0.068 | 38 | 2 | 0.053 | 4 |
| CYP4A11 | CYP4A11 | Q02928 | Cytochrome P450 4A11 | chr1 | GO:0006690 | Not Cancer Driver | No | 131 | 0.252 | 24 | 8 | 0.333 | 0 |
| CYP4A22 | CYP4A22 | Q5TCH4 | Cytochrome P450 4A22 | chr1 | GO:0006690 | Not Cancer Driver | No | 116 | 0.224 | 26 | 6 | 0.231 | 0 |
| CYP4F11 | CYP4F11 | Q9HBI6 | Cytochrome P450 4F11 | chr19 | GO:0006690 | Not Cancer Driver | No | 132 | 0.252 | 11 | 2 | 0.182 | 0 |
| CYP4F12_ENST00000324632 | CYP4F12 | Q9HCS2 | Cytochrome P450 4F12 | chr19 | GO:0006690 | Not Cancer Driver | No | 138 | 0.263 | 18 | 4 | 0.222 | 0 |
| CYP4F2 | CYP4F2 | P78329 | Cytochrome P450 4F2 | chr19 | GO:0006690 | Not Cancer Driver | No | 136 | 0.262 | 17 | 3 | 0.176 | 0 |
| CYP4F22_ENST00000601005 | CYP4F22 | Q6NT55 | Ultra-long-chain fatty acid omega-hydroxylase | chr19 | GO:0006690 | Not Cancer Driver | No | 103 | 0.194 | 30 | 3 | 0.1 | 5 |
| CYP4F3 | CYP4F3 | Q08477 | Cytochrome P450 4F3 | chr19 | GO:0006690 | Not Cancer Driver | No | 125 | 0.24 | 15 | 7 | 0.467 | 0 |
| CYP4F8 | CYP4F8 | P98187 | Cytochrome P450 4F8 | chr19 | GO:0006690 | Not Cancer Driver | No | 108 | 0.208 | 28 | 10 | 0.357 | 0 |
| CYP4Z1 | CYP4Z1 | Q86W10 | Cytochrome P450 4Z1 | chr1 | GO:0006690 | Not Cancer Driver | No | 106 | 0.21 | 14 | 8 | 0.571 | 0 |
| DAGLA | DAGLA | Q9Y4D2 | Diacylglycerol lipase-alpha | chr11 | GO:0006690 | Not Cancer Driver | No | 165 | 0.158 | 315 | 43 | 0.137 | 0 |
| DAGLB | DAGLB | Q8NCG7 | Diacylglycerol lipase-beta | chr7 | GO:0006690 | Not Cancer Driver | No | 69 | 0.103 | 37 | 3 | 0.081 | 0 |
| DPEP2_ENST00000393847 | DPEP2 | Q9H4A9 | Dipeptidase 2 | chr16 | GO:0006690 | Not Cancer Driver | No | 66 | 0.136 | 73 | 4 | 0.055 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0006690 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EDN2 | EDN2 | P20800 | Endothelin-2 | chr1 | GO:0006690 | Not Cancer Driver | No | 21 | 0.118 | 87 | 13 | 0.149 | 0 |
| EPHX1_ENST00000366837 | EPHX1 | P07099 | Epoxide hydrolase 1 | chr1 | GO:0006690 | Not Cancer Driver | No | 75 | 0.165 | 7 | 3 | 0.429 | 0 |
| FAAH | FAAH | O00519 | Fatty-acid amide hydrolase 1 | chr1 | GO:0006690 | Not Cancer Driver | No | 63 | 0.109 | 50 | 14 | 0.28 | 0 |
| FAAH2 | FAAH2 | Q6GMR7 | Fatty-acid amide hydrolase 2 | chrX | GO:0006690 | Not Cancer Driver | No | 111 | 0.209 | 18 | 8 | 0.444 | 0 |
| GGT1_ENST00000248923 | GGT1 | P19440 | Glutathione hydrolase 1 proenzyme | chr22 | GO:0006690 | Not Cancer Driver | No | 83 | 0.146 | 88 | 14 | 0.159 | 0 |
| GGT2 | GGT2P | P36268 | Inactive glutathione hydrolase 2 | chr22 | GO:0006690 | Not Cancer Driver | No | 5 | 0.009 | 48 | 1 | 0.021 | 0 |
| GGT5_ENST00000327365 | GGT5 | P36269 | Glutathione hydrolase 5 proenzyme | chr22 | GO:0006690 | Not Cancer Driver | No | 99 | 0.169 | 122 | 27 | 0.221 | 0 |
| GGT6_ENST00000574154 | GGT6 | Q6P531 | Glutathione hydrolase 6 | chr17 | GO:0006690 | Not Cancer Driver | No | 51 | 0.103 | 211 | 32 | 0.152 | 0 |
| GGT7 | GGT7 | Q9UJ14 | Glutathione hydrolase 7 | chr20 | GO:0006690 | Not Cancer Driver | No | 77 | 0.116 | 170 | 14 | 0.082 | 0 |
| GGTLC1_ENST00000278765 | GGTLC1 | Q9BX51 | Glutathione hydrolase light chain 1 | chr20 | GO:0006690 | Not Cancer Driver | No | 63 | 0.28 | 81 | 17 | 0.21 | 0 |
| GGTLC2 | GGTLC2 | Q14390 | Glutathione hydrolase light chain 2 | chr22 | GO:0006690 | Not Cancer Driver | No | 25 | 0.115 | 119 | 11 | 0.092 | 0 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0006690 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| GPX4_ENST00000616066 | GPX4 | P36969 | Phospholipid hydroperoxide glutathione peroxidase | chr19 | GO:0006690 | Not Cancer Driver | No | 14 | 0.071 | 0 | 0 | 0.0 | 0 |
| HPGD | HPGD | P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | chr4 | GO:0006690 | Not Cancer Driver | No | 32 | 0.12 | 4 | 1 | 0.25 | 2 |
| HPGDS | HPGDS | O60760 | Hematopoietic prostaglandin D synthase | chr4 | GO:0006690 | Not Cancer Driver | No | 34 | 0.171 | 0 | 0 | 0.0 | 0 |
| LTA4H | LTA4H | P09960 | Leukotriene A-4 hydrolase | chr12 | GO:0006690 | Not Cancer Driver | No | 59 | 0.097 | 39 | 6 | 0.154 | 0 |
| LTC4S | LTC4S | Q16873 | Leukotriene C4 synthase | chr5 | GO:0006690 | Not Cancer Driver | No | 3 | 0.02 | 0 | 0 | 0.0 | 0 |
| MAPKAPK2 | MAPKAPK2 | P49137 | MAP kinase-activated protein kinase 2 | chr1 | GO:0006690 | Not Cancer Driver | No | 43 | 0.107 | 92 | 5 | 0.054 | 0 |
| MGLL_ENST00000434178 | MGLL | Q99685 | Monoglyceride lipase | chr3 | GO:0006690 | Not Cancer Driver | No | 54 | 0.178 | 29 | 8 | 0.276 | 0 |
| MGST2 | MGST2 | Q99735 | Microsomal glutathione S-transferase 2 | chr4 | GO:0006690 | Not Cancer Driver | No | 11 | 0.075 | 0 | 0 | 0.0 | 0 |
| MGST3 | MGST3 | O14880 | Microsomal glutathione S-transferase 3 | chr1 | GO:0006690 | Not Cancer Driver | No | 17 | 0.112 | 0 | 0 | 0.0 | 0 |
| MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:0006690 | Not Cancer Driver | No | 4 | 0.035 | 0 | 0 | 0.0 | 0 |
| PLA2G10 | PLA2G10 | O15496 | Group 10 secretory phospholipase A2 | chr16 | GO:0006690 | Not Cancer Driver | No | 5 | 0.03 | 0 | 0 | 0.0 | 0 |
| PLA2G1B | PLA2G1B | P04054 | Phospholipase A2 | chr12 | GO:0006690 | Not Cancer Driver | No | 17 | 0.115 | 0 | 0 | 0.0 | 0 |
| PLA2G3 | PLA2G3 | Q9NZ20 | Group 3 secretory phospholipase A2 | chr22 | GO:0006690 | Not Cancer Driver | No | 115 | 0.226 | 175 | 39 | 0.223 | 0 |
| PLA2G4A | PLA2G4A | P47712 | Cytosolic phospholipase A2 | chr1 | GO:0006690 | Not Cancer Driver | No | 149 | 0.199 | 129 | 28 | 0.217 | 1 |
| PLA2G4B_ENST00000458483 | PLA2G4B | P0C869 | Cytosolic phospholipase A2 beta | chr15 | GO:0006690 | Not Cancer Driver | No | 88 | 0.113 | 144 | 18 | 0.125 | 0 |
| PLA2G4C_ENST00000599921 | PLA2G4C | Q9UP65 | Cytosolic phospholipase A2 gamma | chr19 | GO:0006690 | Not Cancer Driver | No | 107 | 0.198 | 62 | 9 | 0.145 | 0 |
| PLA2G4F | PLA2G4F | Q68DD2 | Cytosolic phospholipase A2 zeta | chr15 | GO:0006690 | Not Cancer Driver | No | 121 | 0.143 | 106 | 6 | 0.057 | 0 |
| PLA2G5 | PLA2G5 | P39877 | Phospholipase A2 group V | chr1 | GO:0006690 | Not Cancer Driver | No | 24 | 0.174 | 0 | 0 | 0.0 | 2 |
| PNPLA8 | PNPLA8 | Q9NP80 | Calcium-independent phospholipase A2-gamma | chr7 | GO:0006690 | Not Cancer Driver | No | 94 | 0.12 | 140 | 18 | 0.129 | 0 |
| PRG3 | PRG3 | Q9Y2Y8 | Proteoglycan 3 | chr11 | GO:0006690 | Not Cancer Driver | No | 40 | 0.178 | 60 | 12 | 0.2 | 0 |
| PTGDS | PTGDS | P41222 | Prostaglandin-H2 D-isomerase | chr9 | GO:0006690 | Not Cancer Driver | No | 31 | 0.163 | 13 | 3 | 0.231 | 0 |
| PTGES | PTGES | O14684 | Prostaglandin E synthase | chr9 | GO:0006690 | Not Cancer Driver | No | 10 | 0.066 | 0 | 0 | 0.0 | 0 |
| PTGES2 | PTGES2 | Q9H7Z7 | Prostaglandin E synthase 2 | chr9 | GO:0006690 | Not Cancer Driver | No | 30 | 0.08 | 30 | 1 | 0.033 | 0 |
| PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | GO:0006690 | Not Cancer Driver | No | 11 | 0.069 | 52 | 3 | 0.058 | 0 |
| PTGIS | PTGIS | Q16647 | Prostacyclin synthase | chr20 | GO:0006690 | Not Cancer Driver | No | 102 | 0.204 | 18 | 3 | 0.167 | 0 |
| PTGR1_ENST00000309195 | PTGR1 | Q14914 | Prostaglandin reductase 1 | chr9 | GO:0006690 | Not Cancer Driver | No | 40 | 0.122 | 12 | 1 | 0.083 | 0 |
| PTGS1 | PTGS1 | P23219 | Prostaglandin G/H synthase 1 | chr9 | GO:0006690 | Not Cancer Driver | No | 123 | 0.205 | 28 | 3 | 0.107 | 0 |
| PTGS2 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0006690 | Not Cancer Driver | No | 105 | 0.174 | 30 | 5 | 0.167 | 0 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0006690 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TBXAS1_ENST00000448866 | TBXAS1 | P24557 | Thromboxane-A synthase | chr7 | GO:0006690 | Not Cancer Driver | No | 116 | 0.218 | 44 | 8 | 0.182 | 4 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0006690 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |