Total number of protein in "GO:0006661" GO term: 61
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATG14 | ATG14 | Q6ZNE5 | Beclin 1-associated autophagy-related key regulator | chr14 | GO:0006661 | Not Cancer Driver | No | 48 | 0.098 | 209 | 24 | 0.115 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0006661 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0006661 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| BMX_ENST00000342014 | BMX | P51813 | Cytoplasmic tyrosine-protein kinase BMX | chrX | GO:0006661 | Not Cancer Driver | No | 106 | 0.157 | 172 | 27 | 0.157 | 0 |
| CDIPT_ENST00000569956 | CDIPT | O14735 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | chr16 | GO:0006661 | Not Cancer Driver | No | 21 | 0.099 | 0 | 0 | 0.0 | 0 |
| CDS1 | CDS1 | Q92903 | Phosphatidate cytidylyltransferase 1 | chr4 | GO:0006661 | Not Cancer Driver | No | 73 | 0.158 | 66 | 9 | 0.136 | 0 |
| DGKE | DGKE | P52429 | Diacylglycerol kinase epsilon | chr17 | GO:0006661 | Not Cancer Driver | No | 84 | 0.148 | 34 | 3 | 0.088 | 2 |
| FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0006661 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
| FIG4 | FIG4 | Q92562 | Polyphosphoinositide phosphatase | chr6 | GO:0006661 | Not Cancer Driver | No | 114 | 0.126 | 177 | 26 | 0.147 | 7 |
| IMPA1_ENST00000256108 | IMPA1 | P29218 | Inositol monophosphatase 1 | chr8 | GO:0006661 | Not Cancer Driver | No | 36 | 0.13 | 3 | 0 | 0.0 | 0 |
| INPP4A | INPP4A | Q96PE3 | Inositol polyphosphate-4-phosphatase type I A | chr2 | GO:0006661 | Not Cancer Driver | No | 114 | 0.117 | 153 | 20 | 0.131 | 0 |
| INPP4B_ENST00000513000 | INPP4B | O15327 | Inositol polyphosphate 4-phosphatase type II | chr4 | GO:0006661 | Not Cancer Driver | No | 145 | 0.157 | 191 | 36 | 0.188 | 0 |
| INPP5D | INPP5D | Q92835 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | chr2 | GO:0006661 | Not Cancer Driver | No | 176 | 0.148 | 578 | 90 | 0.156 | 0 |
| INPP5E | INPP5E | Q9NRR6 | Phosphatidylinositol polyphosphate 5-phosphatase type IV | chr9 | GO:0006661 | Not Cancer Driver | No | 43 | 0.067 | 272 | 16 | 0.059 | 15 |
| INPP5F | INPP5F | Q9Y2H2 | Phosphatidylinositide phosphatase SAC2 | chr10 | GO:0006661 | Not Cancer Driver | No | 138 | 0.122 | 394 | 45 | 0.114 | 0 |
| INPP5J | INPP5J | Q15735 | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A | chr22 | GO:0006661 | Not Cancer Driver | No | 102 | 0.101 | 629 | 42 | 0.067 | 0 |
| INPP5K | INPP5K | Q9BT40 | Inositol polyphosphate 5-phosphatase K | chr17 | GO:0006661 | Not Cancer Driver | No | 42 | 0.094 | 34 | 2 | 0.059 | 7 |
| INPPL1 | INPPL1 | O15357 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | chr11 | GO:0006661 | Not Cancer Driver | No | 174 | 0.138 | 566 | 76 | 0.134 | 4 |
| MBOAT7 | MBOAT7 | Q96N66 | Lysophospholipid acyltransferase 7 | chr19 | GO:0006661 | Not Cancer Driver | No | 69 | 0.146 | 25 | 3 | 0.12 | 0 |
| MTM1 | MTM1 | Q13496 | Myotubularin | chrX | GO:0006661 | Not Cancer Driver | No | 112 | 0.186 | 79 | 9 | 0.114 | 57 |
| MTMR14 | MTMR14 | Q8NCE2 | Myotubularin-related protein 14 | chr3 | GO:0006661 | Not Cancer Driver | No | 58 | 0.089 | 150 | 8 | 0.053 | 2 |
| MTMR1_ENST00000370390 | MTMR1 | Q13613 | Myotubularin-related protein 1 | chrX | GO:0006661 | Not Cancer Driver | No | 114 | 0.171 | 146 | 21 | 0.144 | 0 |
| MTMR2 | MTMR2 | Q13614 | Myotubularin-related protein 2 | chr11 | GO:0006661 | Not Cancer Driver | No | 70 | 0.109 | 140 | 16 | 0.114 | 1 |
| MTMR3 | MTMR3 | Q13615 | Myotubularin-related protein 3 | chr22 | GO:0006661 | Not Cancer Driver | No | 130 | 0.109 | 501 | 66 | 0.132 | 0 |
| MTMR4 | MTMR4 | Q9NYA4 | Myotubularin-related protein 4 | chr17 | GO:0006661 | Not Cancer Driver | No | 147 | 0.123 | 474 | 59 | 0.124 | 0 |
| MTMR6 | MTMR6 | Q9Y217 | Myotubularin-related protein 6 | chr13 | GO:0006661 | Not Cancer Driver | No | 87 | 0.14 | 68 | 16 | 0.235 | 0 |
| MTMR7 | MTMR7 | Q9Y216 | Myotubularin-related protein 7 | chr8 | GO:0006661 | Not Cancer Driver | No | 98 | 0.148 | 160 | 26 | 0.163 | 0 |
| OCRL | OCRL | Q01968 | Inositol polyphosphate 5-phosphatase OCRL | chrX | GO:0006661 | Not Cancer Driver | No | 151 | 0.168 | 126 | 24 | 0.19 | 41 |
| PI4K2A | PI4K2A | Q9BTU6 | Phosphatidylinositol 4-kinase type 2-alpha | chr10 | GO:0006661 | Not Cancer Driver | No | 43 | 0.09 | 129 | 6 | 0.047 | 0 |
| PI4K2B | PI4K2B | Q8TCG2 | Phosphatidylinositol 4-kinase type 2-beta | chr4 | GO:0006661 | Not Cancer Driver | No | 51 | 0.106 | 99 | 4 | 0.04 | 0 |
| PI4KA | PI4KA | P42356 | Phosphatidylinositol 4-kinase alpha | chr22 | GO:0006661 | Not Cancer Driver | No | 267 | 0.127 | 142 | 11 | 0.077 | 1 |
| PI4KB_ENST00000368873 | PI4KB | Q9UBF8 | Phosphatidylinositol 4-kinase beta | chr1 | GO:0006661 | Not Cancer Driver | No | 93 | 0.114 | 311 | 34 | 0.109 | 0 |
| PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0006661 | Not Cancer Driver | No | 187 | 0.111 | 350 | 43 | 0.123 | 0 |
| PIK3C2B | PIK3C2B | O00750 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | chr1 | GO:0006661 | Not Cancer Driver | No | 241 | 0.147 | 425 | 71 | 0.167 | 0 |
| PIK3C2G_ENST00000433979 | PIK3C2G | O75747 | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma | chr12 | GO:0006661 | Not Cancer Driver | No | 283 | 0.196 | 211 | 37 | 0.175 | 0 |
| PIK3C3 | PIK3C3 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | chr18 | GO:0006661 | Not Cancer Driver | No | 127 | 0.143 | 191 | 34 | 0.178 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0006661 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0006661 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0006661 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
| PIK3CG | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0006661 | Not Cancer Driver | No | 318 | 0.289 | 121 | 39 | 0.322 | 0 |
| PIK3R3_ENST00000372006 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | GO:0006661 | Not Cancer Driver | No | 51 | 0.111 | 149 | 20 | 0.134 | 0 |
| PIK3R4 | PIK3R4 | Q99570 | Phosphoinositide 3-kinase regulatory subunit 4 | chr3 | GO:0006661 | Not Cancer Driver | No | 193 | 0.142 | 315 | 45 | 0.143 | 0 |
| PIKFYVE | PIKFYVE | Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinase | chr2 | GO:0006661 | Not Cancer Driver | No | 278 | 0.133 | 848 | 101 | 0.119 | 1 |
| PIP4K2A | PIP4K2A | P48426 | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | chr10 | GO:0006661 | Not Cancer Driver | No | 56 | 0.138 | 123 | 15 | 0.122 | 0 |
| PIP4K2C_ENST00000540759 | PIP4K2C | Q8TBX8 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | chr12 | GO:0006661 | Not Cancer Driver | No | 62 | 0.147 | 111 | 23 | 0.207 | 0 |
| PIP5K1A | PIP5K1A | Q99755 | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | chr1 | GO:0006661 | Not Cancer Driver | No | 74 | 0.132 | 216 | 29 | 0.134 | 0 |
| PIP5K1B | PIP5K1B | O14986 | Phosphatidylinositol 4-phosphate 5-kinase type-1 beta | chr9 | GO:0006661 | Not Cancer Driver | No | 94 | 0.174 | 162 | 36 | 0.222 | 0 |
| PIP5K1C_ENST00000335312 | PIP5K1C | O60331 | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | chr19 | GO:0006661 | Not Cancer Driver | No | 98 | 0.147 | 360 | 60 | 0.167 | 1 |
| PITPNM1_ENST00000534749 | PITPNM1 | O00562 | Membrane-associated phosphatidylinositol transfer protein 1 | chr11 | GO:0006661 | Not Cancer Driver | No | 157 | 0.126 | 477 | 69 | 0.145 | 0 |
| PITPNM2 | PITPNM2 | Q9BZ72 | Membrane-associated phosphatidylinositol transfer protein 2 | chr12 | GO:0006661 | Not Cancer Driver | No | 160 | 0.119 | 535 | 62 | 0.116 | 0 |
| PITPNM3 | PITPNM3 | Q9BZ71 | Membrane-associated phosphatidylinositol transfer protein 3 | chr17 | GO:0006661 | Not Cancer Driver | No | 143 | 0.147 | 334 | 53 | 0.159 | 1 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0006661 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0006661 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| SACM1L | SACM1L | Q9NTJ5 | Phosphatidylinositol-3-phosphatase SAC1 | chr3 | GO:0006661 | Not Cancer Driver | No | 41 | 0.07 | 0 | 0 | 0.0 | 0 |
| SH3YL1 | SH3YL1 | Q96HL8 | SH3 domain-containing YSC84-like protein 1 | chr2 | GO:0006661 | Not Cancer Driver | No | 35 | 0.102 | 108 | 11 | 0.102 | 0 |
| SLC27A1 | SLC27A1 | Q6PCB7 | Long-chain fatty acid transport protein 1 | chr19 | GO:0006661 | Not Cancer Driver | No | 88 | 0.136 | 16 | 0 | 0.0 | 0 |
| SYNJ1 | SYNJ1 | O43426 | Synaptojanin-1 | chr21 | GO:0006661 | Not Cancer Driver | No | 208 | 0.132 | 584 | 76 | 0.13 | 3 |
| SYNJ2 | SYNJ2 | O15056 | Synaptojanin-2 | chr6 | GO:0006661 | Not Cancer Driver | No | 189 | 0.126 | 545 | 70 | 0.128 | 0 |
| TPTE2 | TPTE2 | Q6XPS3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 | chr13 | GO:0006661 | Not Cancer Driver | No | 210 | 0.402 | 33 | 13 | 0.394 | 0 |
| UVRAG | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0006661 | Not Cancer Driver | No | 89 | 0.127 | 243 | 28 | 0.115 | 0 |
| VAC14 | VAC14 | Q08AM6 | Protein VAC14 homolog | chr16 | GO:0006661 | Not Cancer Driver | No | 97 | 0.124 | 116 | 19 | 0.164 | 3 |