Total number of protein in "GO:0006637" GO term: 86
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AADAT_ENST00000515480 | AADAT | Q8N5Z0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | chr4 | GO:0006637 | Not Cancer Driver | No | 48 | 0.113 | 71 | 10 | 0.141 | 0 |
AASS | AASS | Q9UDR5 | Alpha-aminoadipic semialdehyde synthase, mitochondrial | chr7 | GO:0006637 | Not Cancer Driver | No | 161 | 0.174 | 18 | 3 | 0.167 | 0 |
ABCD1 | ABCD1 | P33897 | ATP-binding cassette sub-family D member 1 | chrX | GO:0006637 | Not Cancer Driver | No | 106 | 0.142 | 75 | 5 | 0.067 | 138 |
ACACB_ENST00000377848 | ACACB | O00763 | Acetyl-CoA carboxylase 2 | chr12 | GO:0006637 | Not Cancer Driver | No | 388 | 0.158 | 342 | 62 | 0.181 | 0 |
ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | GO:0006637 | Not Cancer Driver | No | 45 | 0.105 | 32 | 1 | 0.031 | 10 |
ACLY_ENST00000590151 | ACLY | P53396 | ATP-citrate synthase | chr17 | GO:0006637 | Not Cancer Driver | No | 120 | 0.109 | 114 | 12 | 0.105 | 0 |
ACOT1 | ACOT1 | Q86TX2 | Acyl-coenzyme A thioesterase 1 | chr14 | GO:0006637 | Not Cancer Driver | No | 28 | 0.067 | 22 | 0 | 0.0 | 0 |
ACOT11 | ACOT11 | Q8WXI4 | Acyl-coenzyme A thioesterase 11 | chr1 | GO:0006637 | Not Cancer Driver | No | 88 | 0.145 | 110 | 19 | 0.173 | 0 |
ACOT12 | ACOT12 | Q8WYK0 | Acetyl-coenzyme A thioesterase | chr5 | GO:0006637 | Not Cancer Driver | No | 93 | 0.168 | 41 | 3 | 0.073 | 0 |
ACOT2 | ACOT2 | P49753 | Acyl-coenzyme A thioesterase 2, mitochondrial | chr14 | GO:0006637 | Not Cancer Driver | No | 49 | 0.101 | 35 | 5 | 0.143 | 0 |
ACOT4 | ACOT4 | Q8N9L9 | Peroxisomal succinyl-coenzyme A thioesterase | chr14 | GO:0006637 | Not Cancer Driver | No | 53 | 0.126 | 13 | 1 | 0.077 | 0 |
ACOT6_ENST00000645972 | ACOT6 | Q3I5F7 | Acyl-coenzyme A thioesterase 6 | chr14 | GO:0006637 | Not Cancer Driver | No | 30 | 0.071 | 18 | 0 | 0.0 | 0 |
ACOT7 | ACOT7 | O00154 | Cytosolic acyl coenzyme A thioester hydrolase | chr1 | GO:0006637 | Not Cancer Driver | No | 43 | 0.113 | 77 | 16 | 0.208 | 0 |
ACOT8 | ACOT8 | O14734 | Acyl-coenzyme A thioesterase 8 | chr20 | GO:0006637 | Not Cancer Driver | No | 43 | 0.135 | 52 | 7 | 0.135 | 0 |
ACOT9_ENST00000336430 | ACOT9 | Q9Y305 | Acyl-coenzyme A thioesterase 9, mitochondrial | chrX | GO:0006637 | Not Cancer Driver | No | 45 | 0.103 | 45 | 3 | 0.067 | 0 |
ACSBG1 | ACSBG1 | Q96GR2 | Long-chain-fatty-acid--CoA ligase ACSBG1 | chr15 | GO:0006637 | Not Cancer Driver | No | 124 | 0.171 | 107 | 22 | 0.206 | 0 |
ACSBG2_ENST00000591403 | ACSBG2 | Q5FVE4 | Long-chain-fatty-acid--CoA ligase ACSBG2 | chr19 | GO:0006637 | Not Cancer Driver | No | 119 | 0.179 | 37 | 9 | 0.243 | 0 |
ACSF2_ENST00000300441 | ACSF2 | Q96CM8 | Medium-chain acyl-CoA ligase ACSF2, mitochondrial | chr17 | GO:0006637 | Not Cancer Driver | No | 73 | 0.119 | 55 | 10 | 0.182 | 0 |
ACSF3_ENST00000406948 | ACSF3 | Q4G176 | Malonate--CoA ligase ACSF3, mitochondrial | chr16 | GO:0006637 | Not Cancer Driver | No | 87 | 0.151 | 48 | 11 | 0.229 | 9 |
ACSL1_ENST00000281455 | ACSL1 | P33121 | Long-chain-fatty-acid--CoA ligase 1 | chr4 | GO:0006637 | Not Cancer Driver | No | 85 | 0.122 | 27 | 1 | 0.037 | 0 |
ACSL3 | ACSL3 | O95573 | Fatty acid CoA ligase Acsl3 | chr2 | GO:0006637 | Census, Compendium | Yes | 89 | 0.124 | 47 | 7 | 0.149 | 0 |
ACSL4_ENST00000469796 | ACSL4 | O60488 | Long-chain-fatty-acid--CoA ligase 4 | chrX | GO:0006637 | Not Cancer Driver | No | 97 | 0.136 | 77 | 12 | 0.156 | 1 |
ACSL5_ENST00000354655 | ACSL5 | Q9ULC5 | Long-chain-fatty-acid--CoA ligase 5 | chr10 | GO:0006637 | Not Cancer Driver | No | 98 | 0.143 | 22 | 5 | 0.227 | 0 |
ACSL6_ENST00000379240 | ACSL6 | Q9UKU0 | Long-chain-fatty-acid--CoA ligase 6 | chr5 | GO:0006637 | Census | Yes | 120 | 0.172 | 34 | 3 | 0.088 | 0 |
ACSM1_ENST00000520010 | ACSM1 | Q08AH1 | Acyl-coenzyme A synthetase ACSM1, mitochondrial | chr16 | GO:0006637 | Not Cancer Driver | No | 134 | 0.232 | 64 | 16 | 0.25 | 0 |
ACSM2A_ENST00000219054 | ACSM2A | Q08AH3 | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | chr16 | GO:0006637 | Not Cancer Driver | No | 200 | 0.347 | 48 | 24 | 0.5 | 0 |
ACSM2B | ACSM2B | Q68CK6 | Acyl-coenzyme A synthetase ACSM2B, mitochondrial | chr16 | GO:0006637 | Not Cancer Driver | No | 230 | 0.399 | 45 | 23 | 0.511 | 0 |
ACSM3 | ACSM3 | Q53FZ2 | Acyl-coenzyme A synthetase ACSM3, mitochondrial | chr16 | GO:0006637 | Not Cancer Driver | No | 95 | 0.162 | 79 | 8 | 0.101 | 0 |
ACSM4 | ACSM4 | P0C7M7 | Acyl-coenzyme A synthetase ACSM4, mitochondrial | chr12 | GO:0006637 | Not Cancer Driver | No | 128 | 0.221 | 20 | 9 | 0.45 | 0 |
ACSM5 | ACSM5 | Q6NUN0 | Acyl-coenzyme A synthetase ACSM5, mitochondrial | chr16 | GO:0006637 | Not Cancer Driver | No | 152 | 0.263 | 84 | 27 | 0.321 | 0 |
ACSM6_ENST00000394005 | ACSM6 | Q6P461 | Acyl-coenzyme A synthetase ACSM6, mitochondrial | chr10 | GO:0006637 | Not Cancer Driver | No | 56 | 0.117 | 0 | 0 | 0.0 | 0 |
ACSS1 | ACSS1 | Q9NUB1 | Acetyl-coenzyme A synthetase 2-like, mitochondrial | chr20 | GO:0006637 | Not Cancer Driver | No | 79 | 0.115 | 76 | 6 | 0.079 | 0 |
ACSS2_ENST00000360596 | ACSS2 | Q9NR19 | Acetyl-coenzyme A synthetase, cytoplasmic | chr20 | GO:0006637 | Not Cancer Driver | No | 62 | 0.088 | 111 | 6 | 0.054 | 0 |
BAAT_ENST00000395051 | BAAT | Q14032 | Bile acid-CoA:amino acid N-acyltransferase | chr9 | GO:0006637 | Not Cancer Driver | No | 88 | 0.211 | 10 | 4 | 0.4 | 1 |
DGAT1 | DGAT1 | O75907 | Diacylglycerol O-acyltransferase 1 | chr8 | GO:0006637 | Not Cancer Driver | No | 52 | 0.107 | 62 | 0 | 0.0 | 0 |
DGAT2 | DGAT2 | Q96PD7 | Diacylglycerol O-acyltransferase 2 | chr11 | GO:0006637 | Not Cancer Driver | No | 56 | 0.144 | 17 | 2 | 0.118 | 0 |
DIP2A | DIP2A | Q14689 | Disco-interacting protein 2 homolog A | chr21 | GO:0006637 | Not Cancer Driver | No | 204 | 0.13 | 396 | 53 | 0.134 | 0 |
DLAT | DLAT | P10515 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | chr11 | GO:0006637 | Not Cancer Driver | No | 63 | 0.097 | 294 | 42 | 0.143 | 0 |
DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | GO:0006637 | Not Cancer Driver | No | 67 | 0.132 | 17 | 0 | 0.0 | 10 |
DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | GO:0006637 | Not Cancer Driver | No | 53 | 0.117 | 190 | 32 | 0.168 | 1 |
ELOVL1_ENST00000372458 | ELOVL1 | Q9BW60 | Elongation of very long chain fatty acids protein 1 | chr1 | GO:0006637 | Not Cancer Driver | No | 32 | 0.115 | 0 | 0 | 0.0 | 1 |
ELOVL2 | ELOVL2 | Q9NXB9 | Elongation of very long chain fatty acids protein 2 | chr6 | GO:0006637 | Not Cancer Driver | No | 57 | 0.193 | 8 | 2 | 0.25 | 0 |
ELOVL3 | ELOVL3 | Q9HB03 | Elongation of very long chain fatty acids protein 3 | chr10 | GO:0006637 | Not Cancer Driver | No | 42 | 0.156 | 1 | 1 | 1.0 | 0 |
ELOVL4 | ELOVL4 | Q9GZR5 | Elongation of very long chain fatty acids protein 4 | chr6 | GO:0006637 | Not Cancer Driver | No | 68 | 0.217 | 23 | 6 | 0.261 | 1 |
ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | GO:0006637 | Not Cancer Driver | No | 34 | 0.114 | 25 | 4 | 0.16 | 2 |
ELOVL6 | ELOVL6 | Q9H5J4 | Elongation of very long chain fatty acids protein 6 | chr4 | GO:0006637 | Not Cancer Driver | No | 40 | 0.151 | 0 | 0 | 0.0 | 0 |
ELOVL7_ENST00000425382 | ELOVL7 | A1L3X0 | Elongation of very long chain fatty acids protein 7 | chr5 | GO:0006637 | Not Cancer Driver | No | 41 | 0.146 | 10 | 2 | 0.2 | 0 |
FAR1 | FAR1 | Q8WVX9 | Fatty acyl-CoA reductase 1 | chr11 | GO:0006637 | Not Cancer Driver | No | 66 | 0.128 | 0 | 0 | 0.0 | 4 |
FAR2 | FAR2 | Q96K12 | Fatty acyl-CoA reductase 2 | chr12 | GO:0006637 | Not Cancer Driver | No | 63 | 0.122 | 0 | 0 | 0.0 | 0 |
FITM2 | FITM2 | Q8N6M3 | Acyl-coenzyme A diphosphatase FITM2 | chr20 | GO:0006637 | Not Cancer Driver | No | 28 | 0.107 | 0 | 0 | 0.0 | 1 |
GCDH_ENST00000591470 | GCDH | Q92947 | Glutaryl-CoA dehydrogenase, mitochondrial | chr19 | GO:0006637 | Not Cancer Driver | No | 57 | 0.13 | 37 | 5 | 0.135 | 58 |
GLYAT | GLYAT | Q6IB77 | Glycine N-acyltransferase | chr11 | GO:0006637 | Not Cancer Driver | No | 75 | 0.253 | 9 | 2 | 0.222 | 0 |
GPAM | GPAM | Q9HCL2 | Glycerol-3-phosphate acyltransferase 1, mitochondrial | chr10 | GO:0006637 | Not Cancer Driver | No | 108 | 0.13 | 83 | 7 | 0.084 | 0 |
GPAT4 | GPAT4 | Q86UL3 | Glycerol-3-phosphate acyltransferase 4 | chr8 | GO:0006637 | Not Cancer Driver | No | 64 | 0.14 | 3 | 0 | 0.0 | 0 |
HACD1 | HACD1 | B0YJ81 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 | chr10 | GO:0006637 | Not Cancer Driver | No | 74 | 0.257 | 63 | 21 | 0.333 | 0 |
HACD2 | HACD2 | Q6Y1H2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 | chr3 | GO:0006637 | Not Cancer Driver | No | 16 | 0.063 | 14 | 0 | 0.0 | 0 |
HMGCS1_ENST00000433297 | HMGCS1 | Q01581 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | chr5 | GO:0006637 | Not Cancer Driver | No | 64 | 0.123 | 74 | 10 | 0.135 | 0 |
HMGCS2 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0006637 | Not Cancer Driver | No | 92 | 0.181 | 29 | 4 | 0.138 | 19 |
HSD17B12 | HSD17B12 | Q53GQ0 | Very-long-chain 3-oxoacyl-CoA reductase | chr11 | GO:0006637 | Not Cancer Driver | No | 32 | 0.103 | 9 | 0 | 0.0 | 0 |
HSD17B4_ENST00000256216 | HSD17B4 | P51659 | Peroxisomal multifunctional enzyme type 2 | chr5 | GO:0006637 | Not Cancer Driver | No | 99 | 0.135 | 82 | 12 | 0.146 | 4 |
HTD2_ENST00000461393 | HTD2 | P86397 | Hydroxyacyl-thioester dehydratase type 2, mitochondrial | chr3 | GO:0006637 | Not Cancer Driver | No | 1 | 0.006 | 0 | 0 | 0.0 | 0 |
MCEE | MCEE | Q96PE7 | Methylmalonyl-CoA epimerase, mitochondrial | chr2 | GO:0006637 | Not Cancer Driver | No | 19 | 0.108 | 9 | 0 | 0.0 | 0 |
MLYCD | MLYCD | O95822 | Malonyl-CoA decarboxylase, mitochondrial | chr16 | GO:0006637 | Not Cancer Driver | No | 41 | 0.083 | 82 | 0 | 0.0 | 0 |
MPC2 | MPC2 | O95563 | Mitochondrial pyruvate carrier 2 | chr1 | GO:0006637 | Not Cancer Driver | No | 13 | 0.102 | 0 | 0 | 0.0 | 0 |
MVD | MVD | P53602 | Diphosphomevalonate decarboxylase | chr16 | GO:0006637 | Not Cancer Driver | No | 47 | 0.117 | 49 | 10 | 0.204 | 3 |
MVK | MVK | Q03426 | Mevalonate kinase | chr12 | GO:0006637 | Not Cancer Driver | No | 50 | 0.126 | 25 | 0 | 0.0 | 38 |
NUDT19 | NUDT19 | A8MXV4 | Acyl-coenzyme A diphosphatase NUDT19 | chr19 | GO:0006637 | Not Cancer Driver | No | 27 | 0.072 | 131 | 5 | 0.038 | 0 |
NUDT7 | NUDT7 | P0C024 | Peroxisomal coenzyme A diphosphatase NUDT7 | chr16 | GO:0006637 | Not Cancer Driver | No | 45 | 0.189 | 42 | 4 | 0.095 | 0 |
NUDT8 | NUDT8 | Q8WV74 | Mitochondrial coenzyme A diphosphatase NUDT8 | chr11 | GO:0006637 | Not Cancer Driver | No | 22 | 0.093 | 69 | 10 | 0.145 | 0 |
OGDH | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | GO:0006637 | Not Cancer Driver | No | 150 | 0.147 | 106 | 19 | 0.179 | 0 |
OXSM | OXSM | Q9NWU1 | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial | chr3 | GO:0006637 | Not Cancer Driver | No | 62 | 0.135 | 44 | 6 | 0.136 | 0 |
PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | GO:0006637 | Not Cancer Driver | No | 70 | 0.179 | 43 | 6 | 0.14 | 20 |
PDHA2 | PDHA2 | P29803 | Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial | chr4 | GO:0006637 | Not Cancer Driver | No | 163 | 0.42 | 41 | 17 | 0.415 | 0 |
PDHB | PDHB | P11177 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | chr3 | GO:0006637 | Not Cancer Driver | No | 32 | 0.089 | 4 | 0 | 0.0 | 2 |
PDHX | PDHX | O00330 | Pyruvate dehydrogenase protein X component, mitochondrial | chr11 | GO:0006637 | Not Cancer Driver | No | 62 | 0.124 | 179 | 28 | 0.156 | 0 |
PIPOX | PIPOX | Q9P0Z9 | Peroxisomal sarcosine oxidase | chr17 | GO:0006637 | Not Cancer Driver | No | 52 | 0.133 | 21 | 3 | 0.143 | 0 |
PMVK | PMVK | Q15126 | Phosphomevalonate kinase | chr1 | GO:0006637 | Not Cancer Driver | No | 38 | 0.198 | 3 | 0 | 0.0 | 0 |
PPCS | PPCS | Q9HAB8 | Phosphopantothenate--cysteine ligase | chr1 | GO:0006637 | Not Cancer Driver | No | 39 | 0.125 | 13 | 0 | 0.0 | 2 |
PPT1 | PPT1 | P50897 | Palmitoyl-protein thioesterase 1 | chr1 | GO:0006637 | Not Cancer Driver | No | 37 | 0.121 | 0 | 0 | 0.0 | 23 |
PPT2_ENST00000395523 | PPT2 | Q9UMR5 | Lysosomal thioesterase PPT2 | chr6 | GO:0006637 | Compendium | Yes | 45 | 0.149 | 0 | 0 | 0.0 | 0 |
SLC25A1 | SLC25A1 | P53007 | Tricarboxylate transport protein, mitochondrial | chr22 | GO:0006637 | Not Cancer Driver | No | 22 | 0.071 | 34 | 2 | 0.059 | 17 |
SUCLA2 | SUCLA2 | Q9P2R7 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | chr13 | GO:0006637 | Not Cancer Driver | No | 51 | 0.11 | 46 | 6 | 0.13 | 3 |
SUCLG2_ENST00000307227 | SUCLG2 | Q96I99 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | chr3 | GO:0006637 | Not Cancer Driver | No | 48 | 0.111 | 12 | 2 | 0.167 | 0 |
TDO2 | TDO2 | P48775 | Tryptophan 2,3-dioxygenase | chr4 | GO:0006637 | Not Cancer Driver | No | 64 | 0.158 | 31 | 9 | 0.29 | 1 |
TECR | TECR | Q9NZ01 | Very-long-chain enoyl-CoA reductase | chr19 | GO:0006637 | Not Cancer Driver | No | 41 | 0.133 | 0 | 0 | 0.0 | 1 |
THEM5 | THEM5 | Q8N1Q8 | Acyl-coenzyme A thioesterase THEM5 | chr1 | GO:0006637 | Not Cancer Driver | No | 39 | 0.158 | 1 | 0 | 0.0 | 0 |