Total number of protein in "GO:0006633" GO term: 104
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABCD1 | ABCD1 | P33897 | ATP-binding cassette sub-family D member 1 | chrX | GO:0006633 | Not Cancer Driver | No | 106 | 0.142 | 75 | 5 | 0.067 | 138 |
ABCD3 | ABCD3 | P28288 | ATP-binding cassette sub-family D member 3 | chr1 | GO:0006633 | Not Cancer Driver | No | 75 | 0.114 | 21 | 2 | 0.095 | 0 |
ABHD1 | ABHD1 | Q96SE0 | Protein ABHD1 | chr2 | GO:0006633 | Not Cancer Driver | No | 43 | 0.106 | 26 | 3 | 0.115 | 0 |
ABHD2_ENST00000565973 | ABHD2 | P08910 | Monoacylglycerol lipase ABHD2 | chr15 | GO:0006633 | Not Cancer Driver | No | 54 | 0.127 | 8 | 1 | 0.125 | 0 |
ABHD3 | ABHD3 | Q8WU67 | Phospholipase ABHD3 | chr18 | GO:0006633 | Not Cancer Driver | No | 43 | 0.105 | 0 | 0 | 0.0 | 0 |
ACACB_ENST00000377848 | ACACB | O00763 | Acetyl-CoA carboxylase 2 | chr12 | GO:0006633 | Not Cancer Driver | No | 388 | 0.158 | 342 | 62 | 0.181 | 0 |
ACLY_ENST00000590151 | ACLY | P53396 | ATP-citrate synthase | chr17 | GO:0006633 | Not Cancer Driver | No | 120 | 0.109 | 114 | 12 | 0.105 | 0 |
ACOT4 | ACOT4 | Q8N9L9 | Peroxisomal succinyl-coenzyme A thioesterase | chr14 | GO:0006633 | Not Cancer Driver | No | 53 | 0.126 | 13 | 1 | 0.077 | 0 |
ACOT7 | ACOT7 | O00154 | Cytosolic acyl coenzyme A thioester hydrolase | chr1 | GO:0006633 | Not Cancer Driver | No | 43 | 0.113 | 77 | 16 | 0.208 | 0 |
ACSBG1 | ACSBG1 | Q96GR2 | Long-chain-fatty-acid--CoA ligase ACSBG1 | chr15 | GO:0006633 | Not Cancer Driver | No | 124 | 0.171 | 107 | 22 | 0.206 | 0 |
ACSBG2_ENST00000591403 | ACSBG2 | Q5FVE4 | Long-chain-fatty-acid--CoA ligase ACSBG2 | chr19 | GO:0006633 | Not Cancer Driver | No | 119 | 0.179 | 37 | 9 | 0.243 | 0 |
ACSF3_ENST00000406948 | ACSF3 | Q4G176 | Malonate--CoA ligase ACSF3, mitochondrial | chr16 | GO:0006633 | Not Cancer Driver | No | 87 | 0.151 | 48 | 11 | 0.229 | 9 |
ACSM1_ENST00000520010 | ACSM1 | Q08AH1 | Acyl-coenzyme A synthetase ACSM1, mitochondrial | chr16 | GO:0006633 | Not Cancer Driver | No | 134 | 0.232 | 64 | 16 | 0.25 | 0 |
ACSM2A_ENST00000219054 | ACSM2A | Q08AH3 | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | chr16 | GO:0006633 | Not Cancer Driver | No | 200 | 0.347 | 48 | 24 | 0.5 | 0 |
ACSM2B | ACSM2B | Q68CK6 | Acyl-coenzyme A synthetase ACSM2B, mitochondrial | chr16 | GO:0006633 | Not Cancer Driver | No | 230 | 0.399 | 45 | 23 | 0.511 | 0 |
ACSM3 | ACSM3 | Q53FZ2 | Acyl-coenzyme A synthetase ACSM3, mitochondrial | chr16 | GO:0006633 | Not Cancer Driver | No | 95 | 0.162 | 79 | 8 | 0.101 | 0 |
ACSM4 | ACSM4 | P0C7M7 | Acyl-coenzyme A synthetase ACSM4, mitochondrial | chr12 | GO:0006633 | Not Cancer Driver | No | 128 | 0.221 | 20 | 9 | 0.45 | 0 |
ACSM5 | ACSM5 | Q6NUN0 | Acyl-coenzyme A synthetase ACSM5, mitochondrial | chr16 | GO:0006633 | Not Cancer Driver | No | 152 | 0.263 | 84 | 27 | 0.321 | 0 |
ACSM6_ENST00000394005 | ACSM6 | Q6P461 | Acyl-coenzyme A synthetase ACSM6, mitochondrial | chr10 | GO:0006633 | Not Cancer Driver | No | 56 | 0.117 | 0 | 0 | 0.0 | 0 |
ACSS1 | ACSS1 | Q9NUB1 | Acetyl-coenzyme A synthetase 2-like, mitochondrial | chr20 | GO:0006633 | Not Cancer Driver | No | 79 | 0.115 | 76 | 6 | 0.079 | 0 |
ALOX12 | ALOX12 | P18054 | Polyunsaturated fatty acid lipoxygenase ALOX12 | chr17 | GO:0006633 | Not Cancer Driver | No | 73 | 0.11 | 73 | 12 | 0.164 | 0 |
ALOX12B | ALOX12B | O75342 | Arachidonate 12-lipoxygenase, 12R-type | chr17 | GO:0006633 | Not Cancer Driver | No | 101 | 0.144 | 16 | 3 | 0.188 | 18 |
ALOX15B | ALOX15B | O15296 | Polyunsaturated fatty acid lipoxygenase ALOX15B | chr17 | GO:0006633 | Not Cancer Driver | No | 99 | 0.146 | 62 | 12 | 0.194 | 0 |
ALOX15_ENST00000293761 | ALOX15 | P16050 | Polyunsaturated fatty acid lipoxygenase ALOX15 | chr17 | GO:0006633 | Not Cancer Driver | No | 84 | 0.127 | 46 | 7 | 0.152 | 0 |
ALOX5 | ALOX5 | P09917 | Polyunsaturated fatty acid 5-lipoxygenase | chr10 | GO:0006633 | Not Cancer Driver | No | 129 | 0.191 | 16 | 2 | 0.125 | 0 |
ALOXE3_ENST00000448843 | ALOXE3 | Q9BYJ1 | Hydroperoxide isomerase ALOXE3 | chr17 | GO:0006633 | Not Cancer Driver | No | 108 | 0.152 | 69 | 13 | 0.188 | 6 |
ASAH2 | ASAH2 | Q9NR71 | Neutral ceramidase | chr10 | GO:0006633 | Not Cancer Driver | No | 71 | 0.091 | 140 | 24 | 0.171 | 0 |
ASAH2B_ENST00000374006 | ASAH2B | P0C7U1 | Putative inactive neutral ceramidase B | chr10 | GO:0006633 | Not Cancer Driver | No | 9 | 0.055 | 14 | 1 | 0.071 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0006633 | Census, Compendium | Yes | 224 | 0.12 | 1458 | 174 | 0.119 | 35 |
CBR4 | CBR4 | Q8N4T8 | 3-oxoacyl-[acyl-carrier-protein] reductase | chr4 | GO:0006633 | Not Cancer Driver | No | 15 | 0.063 | 4 | 0 | 0.0 | 0 |
CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0006633 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0006633 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
CYP1A2 | CYP1A2 | P05177 | Cytochrome P450 1A2 | chr15 | GO:0006633 | Not Cancer Driver | No | 93 | 0.18 | 23 | 3 | 0.13 | 0 |
CYP2C8 | CYP2C8 | P10632 | Cytochrome P450 2C8 | chr10 | GO:0006633 | Census, Compendium | Yes | 113 | 0.231 | 30 | 11 | 0.367 | 0 |
CYP2C9 | CYP2C9 | P11712 | Cytochrome P450 2C9 | chr10 | GO:0006633 | Not Cancer Driver | No | 122 | 0.249 | 36 | 14 | 0.389 | 0 |
CYP2D6_ENST00000645361 | CYP2D6 | P10635 | Cytochrome P450 2D6 | chr22 | GO:0006633 | Not Cancer Driver | No | 76 | 0.153 | 66 | 8 | 0.121 | 0 |
CYP2E1_ENST00000252945 | CYP2E1 | P05181 | Cytochrome P450 2E1 | chr10 | GO:0006633 | Not Cancer Driver | No | 87 | 0.176 | 21 | 6 | 0.286 | 0 |
CYP3A4 | CYP3A4 | P08684 | Cytochrome P450 3A4 | chr7 | GO:0006633 | Not Cancer Driver | No | 91 | 0.181 | 22 | 2 | 0.091 | 1 |
DAGLB | DAGLB | Q8NCG7 | Diacylglycerol lipase-beta | chr7 | GO:0006633 | Not Cancer Driver | No | 69 | 0.103 | 37 | 3 | 0.081 | 0 |
EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0006633 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
EDN2 | EDN2 | P20800 | Endothelin-2 | chr1 | GO:0006633 | Not Cancer Driver | No | 21 | 0.118 | 87 | 13 | 0.149 | 0 |
ELOVL1_ENST00000372458 | ELOVL1 | Q9BW60 | Elongation of very long chain fatty acids protein 1 | chr1 | GO:0006633 | Not Cancer Driver | No | 32 | 0.115 | 0 | 0 | 0.0 | 1 |
ELOVL2 | ELOVL2 | Q9NXB9 | Elongation of very long chain fatty acids protein 2 | chr6 | GO:0006633 | Not Cancer Driver | No | 57 | 0.193 | 8 | 2 | 0.25 | 0 |
ELOVL3 | ELOVL3 | Q9HB03 | Elongation of very long chain fatty acids protein 3 | chr10 | GO:0006633 | Not Cancer Driver | No | 42 | 0.156 | 1 | 1 | 1.0 | 0 |
ELOVL4 | ELOVL4 | Q9GZR5 | Elongation of very long chain fatty acids protein 4 | chr6 | GO:0006633 | Not Cancer Driver | No | 68 | 0.217 | 23 | 6 | 0.261 | 1 |
ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | GO:0006633 | Not Cancer Driver | No | 34 | 0.114 | 25 | 4 | 0.16 | 2 |
ELOVL6 | ELOVL6 | Q9H5J4 | Elongation of very long chain fatty acids protein 6 | chr4 | GO:0006633 | Not Cancer Driver | No | 40 | 0.151 | 0 | 0 | 0.0 | 0 |
ELOVL7_ENST00000425382 | ELOVL7 | A1L3X0 | Elongation of very long chain fatty acids protein 7 | chr5 | GO:0006633 | Not Cancer Driver | No | 41 | 0.146 | 10 | 2 | 0.2 | 0 |
FA2H | FA2H | Q7L5A8 | Fatty acid 2-hydroxylase | chr16 | GO:0006633 | Not Cancer Driver | No | 33 | 0.089 | 73 | 0 | 0.0 | 3 |
FADS6_ENST00000614223 | FADS6 | Q8N9I5 | Fatty acid desaturase 6 | chr17 | GO:0006633 | Not Cancer Driver | No | 36 | 0.101 | 27 | 2 | 0.074 | 0 |
FASN | FASN | P49327 | Fatty acid synthase | chr17 | GO:0006633 | Not Cancer Driver | No | 291 | 0.116 | 309 | 42 | 0.136 | 0 |
GPX4_ENST00000616066 | GPX4 | P36969 | Phospholipid hydroperoxide glutathione peroxidase | chr19 | GO:0006633 | Not Cancer Driver | No | 14 | 0.071 | 0 | 0 | 0.0 | 0 |
GSTM1 | GSTM1 | P09488 | Glutathione S-transferase Mu 1 | chr1 | GO:0006633 | Not Cancer Driver | No | 17 | 0.078 | 7 | 1 | 0.143 | 0 |
GSTM2 | GSTM2 | P28161 | Glutathione S-transferase Mu 2 | chr1 | GO:0006633 | Not Cancer Driver | No | 26 | 0.119 | 5 | 0 | 0.0 | 0 |
GSTM4 | GSTM4 | Q03013 | Glutathione S-transferase Mu 4 | chr1 | GO:0006633 | Not Cancer Driver | No | 24 | 0.11 | 4 | 1 | 0.25 | 0 |
GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | GO:0006633 | Not Cancer Driver | No | 32 | 0.152 | 0 | 0 | 0.0 | 0 |
HACD1 | HACD1 | B0YJ81 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 | chr10 | GO:0006633 | Not Cancer Driver | No | 74 | 0.257 | 63 | 21 | 0.333 | 0 |
HACD2 | HACD2 | Q6Y1H2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 | chr3 | GO:0006633 | Not Cancer Driver | No | 16 | 0.063 | 14 | 0 | 0.0 | 0 |
HACD3 | HACD3 | Q9P035 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 | chr15 | GO:0006633 | Not Cancer Driver | No | 28 | 0.077 | 10 | 0 | 0.0 | 0 |
HACD4 | HACD4 | Q5VWC8 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 | chr9 | GO:0006633 | Not Cancer Driver | No | 30 | 0.129 | 0 | 0 | 0.0 | 0 |
HPGDS | HPGDS | O60760 | Hematopoietic prostaglandin D synthase | chr4 | GO:0006633 | Not Cancer Driver | No | 34 | 0.171 | 0 | 0 | 0.0 | 0 |
HSD17B12 | HSD17B12 | Q53GQ0 | Very-long-chain 3-oxoacyl-CoA reductase | chr11 | GO:0006633 | Not Cancer Driver | No | 32 | 0.103 | 9 | 0 | 0.0 | 0 |
HSD17B8 | HSD17B8 | Q92506 | (3R)-3-hydroxyacyl-CoA dehydrogenase | chr6 | GO:0006633 | Not Cancer Driver | No | 20 | 0.077 | 26 | 1 | 0.038 | 0 |
LIAS | LIAS | O43766 | Lipoyl synthase, mitochondrial | chr4 | GO:0006633 | Not Cancer Driver | No | 46 | 0.124 | 82 | 10 | 0.122 | 1 |
LIPC_ENST00000356113 | LIPC | P11150 | Hepatic triacylglycerol lipase | chr15 | GO:0006633 | Not Cancer Driver | No | 91 | 0.182 | 17 | 3 | 0.176 | 2 |
LIPG | LIPG | Q9Y5X9 | Endothelial lipase | chr18 | GO:0006633 | Not Cancer Driver | No | 90 | 0.18 | 59 | 7 | 0.119 | 0 |
LIPH | LIPH | Q8WWY8 | Lipase member H | chr3 | GO:0006633 | Not Cancer Driver | No | 71 | 0.157 | 32 | 8 | 0.25 | 2 |
LIPI_ENST00000536861 | LIPI | Q6XZB0 | Lipase member I | chr21 | GO:0006633 | Not Cancer Driver | No | 142 | 0.309 | 5 | 0 | 0.0 | 1 |
LPL | LPL | P06858 | Lipoprotein lipase | chr8 | GO:0006633 | Not Cancer Driver | No | 94 | 0.198 | 23 | 3 | 0.13 | 70 |
LTC4S | LTC4S | Q16873 | Leukotriene C4 synthase | chr5 | GO:0006633 | Not Cancer Driver | No | 3 | 0.02 | 0 | 0 | 0.0 | 0 |
MCAT | MCAT | Q8IVS2 | Malonyl-CoA-acyl carrier protein transacylase, mitochondrial | chr22 | GO:0006633 | Not Cancer Driver | No | 38 | 0.097 | 52 | 2 | 0.038 | 0 |
MECR | MECR | Q9BV79 | Enoyl-[acyl-carrier-protein] reductase, mitochondrial | chr1 | GO:0006633 | Not Cancer Driver | No | 55 | 0.147 | 26 | 5 | 0.192 | 3 |
MGLL_ENST00000434178 | MGLL | Q99685 | Monoglyceride lipase | chr3 | GO:0006633 | Not Cancer Driver | No | 54 | 0.178 | 29 | 8 | 0.276 | 0 |
MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:0006633 | Not Cancer Driver | No | 4 | 0.035 | 0 | 0 | 0.0 | 0 |
MLYCD | MLYCD | O95822 | Malonyl-CoA decarboxylase, mitochondrial | chr16 | GO:0006633 | Not Cancer Driver | No | 41 | 0.083 | 82 | 0 | 0.0 | 0 |
NDUFAB1_ENST00000007516 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial | chr16 | GO:0006633 | Not Cancer Driver | No | 23 | 0.147 | 0 | 0 | 0.0 | 0 |
OLAH_ENST00000378228 | OLAH | Q9NV23 | S-acyl fatty acid synthase thioesterase, medium chain | chr10 | GO:0006633 | Not Cancer Driver | No | 53 | 0.2 | 44 | 13 | 0.295 | 0 |
OXSM | OXSM | Q9NWU1 | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial | chr3 | GO:0006633 | Not Cancer Driver | No | 62 | 0.135 | 44 | 6 | 0.136 | 0 |
PECR | PECR | Q9BY49 | Peroxisomal trans-2-enoyl-CoA reductase | chr2 | GO:0006633 | Not Cancer Driver | No | 29 | 0.096 | 8 | 0 | 0.0 | 0 |
PLA2G10 | PLA2G10 | O15496 | Group 10 secretory phospholipase A2 | chr16 | GO:0006633 | Not Cancer Driver | No | 5 | 0.03 | 0 | 0 | 0.0 | 0 |
PLA2G1B | PLA2G1B | P04054 | Phospholipase A2 | chr12 | GO:0006633 | Not Cancer Driver | No | 17 | 0.115 | 0 | 0 | 0.0 | 0 |
PLA2G4A | PLA2G4A | P47712 | Cytosolic phospholipase A2 | chr1 | GO:0006633 | Not Cancer Driver | No | 149 | 0.199 | 129 | 28 | 0.217 | 1 |
PLA2G4F | PLA2G4F | Q68DD2 | Cytosolic phospholipase A2 zeta | chr15 | GO:0006633 | Not Cancer Driver | No | 121 | 0.143 | 106 | 6 | 0.057 | 0 |
PLP1 | PLP1 | P60201 | Myelin proteolipid protein | chrX | GO:0006633 | Not Cancer Driver | No | 49 | 0.177 | 5 | 1 | 0.2 | 72 |
PNPLA8 | PNPLA8 | Q9NP80 | Calcium-independent phospholipase A2-gamma | chr7 | GO:0006633 | Not Cancer Driver | No | 94 | 0.12 | 140 | 18 | 0.129 | 0 |
PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0006633 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0006633 | Not Cancer Driver | No | 128 | 0.232 | 98 | 26 | 0.265 | 0 |
PRKAB1 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | GO:0006633 | Not Cancer Driver | No | 39 | 0.144 | 124 | 13 | 0.105 | 0 |
PRKAB2 | PRKAB2 | O43741 | 5'-AMP-activated protein kinase subunit beta-2 | chr1 | GO:0006633 | Not Cancer Driver | No | 31 | 0.114 | 110 | 12 | 0.109 | 0 |
PRKAG1_ENST00000548065 | PRKAG1 | P54619 | 5'-AMP-activated protein kinase subunit gamma-1 | chr12 | GO:0006633 | Not Cancer Driver | No | 35 | 0.106 | 25 | 2 | 0.08 | 0 |
PRKAG2 | PRKAG2 | Q9UGJ0 | 5'-AMP-activated protein kinase subunit gamma-2 | chr7 | GO:0006633 | Not Cancer Driver | No | 76 | 0.134 | 240 | 45 | 0.188 | 7 |
PRKAG3_ENST00000529249 | PRKAG3 | Q9UGI9 | 5'-AMP-activated protein kinase subunit gamma-3 | chr2 | GO:0006633 | Not Cancer Driver | No | 74 | 0.151 | 144 | 25 | 0.174 | 0 |
PTGDS | PTGDS | P41222 | Prostaglandin-H2 D-isomerase | chr9 | GO:0006633 | Not Cancer Driver | No | 31 | 0.163 | 13 | 3 | 0.231 | 0 |
PTGES | PTGES | O14684 | Prostaglandin E synthase | chr9 | GO:0006633 | Not Cancer Driver | No | 10 | 0.066 | 0 | 0 | 0.0 | 0 |
PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | GO:0006633 | Not Cancer Driver | No | 11 | 0.069 | 52 | 3 | 0.058 | 0 |
PTGIS | PTGIS | Q16647 | Prostacyclin synthase | chr20 | GO:0006633 | Not Cancer Driver | No | 102 | 0.204 | 18 | 3 | 0.167 | 0 |
PTGS1 | PTGS1 | P23219 | Prostaglandin G/H synthase 1 | chr9 | GO:0006633 | Not Cancer Driver | No | 123 | 0.205 | 28 | 3 | 0.107 | 0 |
PTGS2 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0006633 | Not Cancer Driver | No | 105 | 0.174 | 30 | 5 | 0.167 | 0 |
QKI | QKI | Q96PU8 | Protein quaking | chr6 | GO:0006633 | Census, Compendium | Yes | 52 | 0.152 | 174 | 27 | 0.155 | 0 |
TBXAS1_ENST00000448866 | TBXAS1 | P24557 | Thromboxane-A synthase | chr7 | GO:0006633 | Not Cancer Driver | No | 116 | 0.218 | 44 | 8 | 0.182 | 4 |
TECR | TECR | Q9NZ01 | Very-long-chain enoyl-CoA reductase | chr19 | GO:0006633 | Not Cancer Driver | No | 41 | 0.133 | 0 | 0 | 0.0 | 1 |
TECRL | TECRL | Q5HYJ1 | Trans-2,3-enoyl-CoA reductase-like | chr4 | GO:0006633 | Not Cancer Driver | No | 147 | 0.405 | 6 | 4 | 0.667 | 0 |
THNSL2 | THNSL2 | Q86YJ6 | Threonine synthase-like 2 | chr2 | GO:0006633 | Not Cancer Driver | No | 73 | 0.151 | 51 | 3 | 0.059 | 0 |
XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0006633 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |