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Total number of protein in "GO:0006575" GO term:  131

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AASDHPPT AASDHPPT Q9NRN7 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase chr11 GO:0006575 Not Cancer Driver No 52 0.168 27 2 0.074 0
ABHD12B ABHD12B Q7Z5M8 Protein ABHD12B chr14 GO:0006575 Not Cancer Driver No 34 0.094 16 1 0.062 0
ABHD12_ENST00000339157 ABHD12 Q8N2K0 Lysophosphatidylserine lipase ABHD12 chr20 GO:0006575 Not Cancer Driver No 45 0.113 8 1 0.125 1
ABHD16A ABHD16A O95870 Phosphatidylserine lipase ABHD16A chr6 GO:0006575 Not Cancer Driver No 69 0.124 53 15 0.283 0
ABHD16B ABHD16B Q9H3Z7 Protein ABHD16B chr20 GO:0006575 Not Cancer Driver No 41 0.087 31 2 0.065 0
ACADL ACADL P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial chr2 GO:0006575 Not Cancer Driver No 63 0.147 51 3 0.059 0
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 GO:0006575 Not Cancer Driver No 61 0.145 41 5 0.122 19
ALDH1L1_ENST00000393434 ALDH1L1 O75891 Cytosolic 10-formyltetrahydrofolate dehydrogenase chr3 GO:0006575 Not Cancer Driver No 159 0.176 87 19 0.218 0
ALDH1L2 ALDH1L2 Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase chr12 GO:0006575 Not Cancer Driver No 108 0.117 81 12 0.148 0
ALDH4A1 ALDH4A1 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial chr1 GO:0006575 Not Cancer Driver No 63 0.112 46 9 0.196 1
ALDH7A1 ALDH7A1 P49419 Alpha-aminoadipic semialdehyde dehydrogenase chr5 GO:0006575 Not Cancer Driver No 52 0.096 26 1 0.038 8
ALDH9A1 ALDH9A1 P49189 4-trimethylaminobutyraldehyde dehydrogenase chr1 GO:0006575 Not Cancer Driver No 57 0.115 16 0 0.0 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0006575 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 GO:0006575 Census Yes 74 0.125 25 1 0.04 1
BBOX1_ENST00000525090 BBOX1 O75936 Gamma-butyrobetaine dioxygenase chr11 GO:0006575 Not Cancer Driver No 59 0.152 0 0 0.0 0
BHMT BHMT Q93088 Betaine--homocysteine S-methyltransferase 1 chr5 GO:0006575 Not Cancer Driver No 78 0.192 93 12 0.129 0
BHMT2 BHMT2 Q9H2M3 S-methylmethionine--homocysteine S-methyltransferase BHMT2 chr5 GO:0006575 Not Cancer Driver No 54 0.149 30 4 0.133 0
CGA_ENST00000627148 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0006575 Not Cancer Driver No 28 0.241 0 0 0.0 0
CHAC1_ENST00000617961 CHAC1 Q9BUX1 Glutathione-specific gamma-glutamylcyclotransferase 1 chr15 GO:0006575 Not Cancer Driver No 30 0.135 49 5 0.102 0
CHAC2 CHAC2 Q8WUX2 Glutathione-specific gamma-glutamylcyclotransferase 2 chr2 GO:0006575 Not Cancer Driver No 21 0.114 11 2 0.182 0
CHDH CHDH Q8NE62 Choline dehydrogenase, mitochondrial chr3 GO:0006575 Not Cancer Driver No 59 0.099 116 7 0.06 0
CKB CKB P12277 Creatine kinase B-type chr14 GO:0006575 Not Cancer Driver No 31 0.081 102 4 0.039 0
CKM CKM P06732 Creatine kinase M-type chr19 GO:0006575 Not Cancer Driver No 58 0.152 118 19 0.161 0
CKMT1B_ENST00000441322 CKMT1B P12532 Creatine kinase U-type, mitochondrial chr15 GO:0006575 Not Cancer Driver No 25 0.06 77 1 0.013 0
CKMT2_ENST00000437669 CKMT2 P17540 Creatine kinase S-type, mitochondrial chr5 GO:0006575 Not Cancer Driver No 70 0.167 68 12 0.176 0
CPQ CPQ Q9Y646 Carboxypeptidase Q chr8 GO:0006575 Not Cancer Driver No 110 0.233 3 0 0.0 0
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0006575 Not Cancer Driver No 144 0.186 62 10 0.161 15
CPT1B_ENST00000405237 CPT1B Q92523 Carnitine O-palmitoyltransferase 1, muscle isoform chr22 GO:0006575 Not Cancer Driver No 89 0.115 50 8 0.16 0
CPT1C_ENST00000598293 CPT1C Q8TCG5 Carnitine O-palmitoyltransferase 1, brain isoform chr19 GO:0006575 Not Cancer Driver No 138 0.172 93 13 0.14 1
CPT2 CPT2 P23786 Carnitine O-palmitoyltransferase 2, mitochondrial chr1 GO:0006575 Not Cancer Driver No 66 0.1 70 5 0.071 21
CRAT CRAT P43155 Carnitine O-acetyltransferase chr9 GO:0006575 Not Cancer Driver No 74 0.118 27 4 0.148 0
CROT_ENST00000331536 CROT Q9UKG9 Peroxisomal carnitine O-octanoyltransferase chr7 GO:0006575 Not Cancer Driver No 107 0.175 32 2 0.062 0
CRYM CRYM Q14894 Ketimine reductase mu-crystallin chr16 GO:0006575 Not Cancer Driver No 34 0.108 10 0 0.0 1
CTSB CTSB P07858 Cathepsin B chr8 GO:0006575 Not Cancer Driver No 41 0.121 7 2 0.286 0
CTSK CTSK P43235 Cathepsin K chr1 GO:0006575 Not Cancer Driver No 36 0.109 24 4 0.167 6
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0006575 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 GO:0006575 Not Cancer Driver No 25 0.134 20 0 0.0 0
DIO1_ENST00000613679 DIO1 P49895 Type I iodothyronine deiodinase chr1 GO:0006575 Not Cancer Driver No 28 0.112 0 0 0.0 0
DIO2_ENST00000557010 DIO2 Q92813 Type II iodothyronine deiodinase chr14 GO:0006575 Not Cancer Driver No 73 0.267 44 4 0.091 0
DIO3 DIO3 P55073 Thyroxine 5-deiodinase chr14 GO:0006575 Not Cancer Driver No 88 0.289 71 18 0.254 0
DMGDH DMGDH Q9UI17 Dimethylglycine dehydrogenase, mitochondrial chr5 GO:0006575 Not Cancer Driver No 155 0.179 74 12 0.162 1
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0006575 Not Cancer Driver No 54 0.131 41 6 0.146 0
DUOX1 DUOX1 Q9NRD9 Dual oxidase 1 chr15 GO:0006575 Not Cancer Driver No 193 0.124 158 17 0.108 0
DUOX2 DUOX2 Q9NRD8 Dual oxidase 2 chr15 GO:0006575 Not Cancer Driver No 245 0.158 182 25 0.137 3
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0006575 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOXE1 FOXE1 O00358 Forkhead box protein E1 chr9 GO:0006575 Not Cancer Driver No 38 0.102 133 5 0.038 4
FPGS FPGS Q05932 Folylpolyglutamate synthase, mitochondrial chr9 GO:0006575 Not Cancer Driver No 68 0.116 141 18 0.128 0
FTCD_ENST00000291670 FTCD O95954 Formimidoyltransferase-cyclodeaminase chr21 GO:0006575 Not Cancer Driver No 86 0.159 44 36 0.818 2
GAMT_ENST00000252288 GAMT Q14353 Guanidinoacetate N-methyltransferase chr19 GO:0006575 Not Cancer Driver No 29 0.123 12 0 0.0 18
GART_ENST00000381815 GART P22102 Trifunctional purine biosynthetic protein adenosine-3 chr21 GO:0006575 Not Cancer Driver No 96 0.095 50 6 0.12 0
GATM GATM P50440 Glycine amidinotransferase, mitochondrial chr15 GO:0006575 Not Cancer Driver No 69 0.163 33 8 0.242 15
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0006575 Not Cancer Driver No 20 0.08 99 5 0.051 38
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0006575 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0006575 Not Cancer Driver No 32 0.117 31 3 0.097 0
GCNT4 GCNT4 Q9P109 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 chr5 GO:0006575 Not Cancer Driver No 64 0.141 0 0 0.0 0
GGACT GGACT Q9BVM4 Gamma-glutamylaminecyclotransferase chr13 GO:0006575 Not Cancer Driver No 4 0.026 51 0 0.0 0
GGH GGH Q92820 Gamma-glutamyl hydrolase chr8 GO:0006575 Not Cancer Driver No 46 0.145 5 0 0.0 0
GGT1_ENST00000248923 GGT1 P19440 Glutathione hydrolase 1 proenzyme chr22 GO:0006575 Not Cancer Driver No 83 0.146 88 14 0.159 0
GGT2 GGT2P P36268 Inactive glutathione hydrolase 2 chr22 GO:0006575 Not Cancer Driver No 5 0.009 48 1 0.021 0
GGT5_ENST00000327365 GGT5 P36269 Glutathione hydrolase 5 proenzyme chr22 GO:0006575 Not Cancer Driver No 99 0.169 122 27 0.221 0
GGT6_ENST00000574154 GGT6 Q6P531 Glutathione hydrolase 6 chr17 GO:0006575 Not Cancer Driver No 51 0.103 211 32 0.152 0
GGT7 GGT7 Q9UJ14 Glutathione hydrolase 7 chr20 GO:0006575 Not Cancer Driver No 77 0.116 170 14 0.082 0
GGTLC1_ENST00000278765 GGTLC1 Q9BX51 Glutathione hydrolase light chain 1 chr20 GO:0006575 Not Cancer Driver No 63 0.28 81 17 0.21 0
GGTLC2 GGTLC2 Q14390 Glutathione hydrolase light chain 2 chr22 GO:0006575 Not Cancer Driver No 25 0.115 119 11 0.092 0
GNMT GNMT Q14749 Glycine N-methyltransferase chr6 GO:0006575 Not Cancer Driver No 25 0.085 0 0 0.0 3
GOT2 GOT2 P00505 Aspartate aminotransferase, mitochondrial chr16 GO:0006575 Not Cancer Driver No 61 0.142 25 3 0.12 1
GSS_ENST00000216951 GSS P48637 Glutathione synthetase chr20 GO:0006575 Not Cancer Driver No 61 0.129 49 6 0.122 14
HAGH HAGH Q16775 Hydroxyacylglutathione hydrolase, mitochondrial chr16 GO:0006575 Not Cancer Driver No 26 0.084 41 1 0.024 0
HOGA1 HOGA1 Q86XE5 4-hydroxy-2-oxoglutarate aldolase, mitochondrial chr10 GO:0006575 Not Cancer Driver No 34 0.104 2 0 0.0 2
ICMT ICMT O60725 Protein-S-isoprenylcysteine O-methyltransferase chr1 GO:0006575 Not Cancer Driver No 24 0.085 0 0 0.0 0
IYD_ENST00000344419 IYD Q6PHW0 Iodotyrosine deiodinase 1 chr6 GO:0006575 Not Cancer Driver No 53 0.183 75 21 0.28 2
KYAT1_ENST00000302586 KYAT1 Q16773 Kynurenine--oxoglutarate transaminase 1 chr9 GO:0006575 Not Cancer Driver No 56 0.133 5 1 0.2 0
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0006575 Not Cancer Driver No 54 0.111 1 0 0.0 0
LPCAT4 LPCAT4 Q643R3 Lysophospholipid acyltransferase LPCAT4 chr15 GO:0006575 Not Cancer Driver No 52 0.099 92 10 0.109 0
MBOAT1 MBOAT1 Q6ZNC8 Lysophospholipid acyltransferase 1 chr6 GO:0006575 Not Cancer Driver No 59 0.119 15 5 0.333 0
MBOAT2 MBOAT2 Q6ZWT7 Lysophospholipid acyltransferase 2 chr2 GO:0006575 Not Cancer Driver No 59 0.113 36 6 0.167 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0006575 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MGST2 MGST2 Q99735 Microsomal glutathione S-transferase 2 chr4 GO:0006575 Not Cancer Driver No 11 0.075 0 0 0.0 0
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 GO:0006575 Not Cancer Driver No 103 0.11 129 11 0.085 6
MTHFD1L_ENST00000367321 MTHFD1L Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 GO:0006575 Not Cancer Driver No 117 0.12 139 11 0.079 0
MTHFD2 MTHFD2 P13995 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial chr2 GO:0006575 Not Cancer Driver No 39 0.111 39 3 0.077 0
MTHFD2L MTHFD2L Q9H903 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial chr4 GO:0006575 Not Cancer Driver No 45 0.13 59 6 0.102 0
MTHFR_ENST00000376590 MTHFR P42898 Methylenetetrahydrofolate reductase chr1 GO:0006575 Not Cancer Driver No 95 0.145 125 22 0.176 53
MTHFS MTHFS P49914 5-formyltetrahydrofolate cyclo-ligase chr15 GO:0006575 Not Cancer Driver No 18 0.089 36 6 0.167 2
MTRR_ENST00000440940 MTRR Q9UBK8 Methionine synthase reductase chr5 GO:0006575 Not Cancer Driver No 101 0.145 84 13 0.155 5
OSBPL10 OSBPL10 Q9BXB5 Oxysterol-binding protein-related protein 10 chr3 GO:0006575 Not Cancer Driver No 113 0.148 366 63 0.172 0
OSBPL5 OSBPL5 Q9H0X9 Oxysterol-binding protein-related protein 5 chr11 GO:0006575 Not Cancer Driver No 100 0.114 444 43 0.097 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0006575 Not Cancer Driver No 105 0.118 401 37 0.092 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 GO:0006575 Not Cancer Driver No 46 0.081 206 14 0.068 30
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0006575 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCYOX1 PCYOX1 Q9UHG3 Prenylcysteine oxidase 1 chr2 GO:0006575 Not Cancer Driver No 60 0.119 9 1 0.111 0
PCYOX1L PCYOX1L Q8NBM8 Prenylcysteine oxidase-like chr5 GO:0006575 Not Cancer Driver No 61 0.123 0 0 0.0 0
PIPOX PIPOX Q9P0Z9 Peroxisomal sarcosine oxidase chr17 GO:0006575 Not Cancer Driver No 52 0.133 21 3 0.143 0
PLA1A PLA1A Q53H76 Phospholipase A1 member A chr3 GO:0006575 Not Cancer Driver No 94 0.206 10 0 0.0 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0006575 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G15 PLA2G15 Q8NCC3 Phospholipase A2 group XV chr16 GO:0006575 Not Cancer Driver No 61 0.148 11 3 0.273 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0006575 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLOD2_ENST00000360060 PLOD2 O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 chr3 GO:0006575 Not Cancer Driver No 109 0.148 17 3 0.176 4
PLOD3 PLOD3 O60568 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 GO:0006575 Not Cancer Driver No 108 0.146 65 8 0.123 1
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0006575 Not Cancer Driver No 43 0.135 92 13 0.141 0
PM20D2 PM20D2 Q8IYS1 Xaa-Arg dipeptidase chr6 GO:0006575 Not Cancer Driver No 39 0.089 79 7 0.089 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0006575 Not Cancer Driver No 62 0.092 93 4 0.043 9
PRODH_ENST00000610940 PRODH O43272 Proline dehydrogenase 1, mitochondrial chr22 GO:0006575 Not Cancer Driver No 62 0.103 67 8 0.119 16
PTDSS1 PTDSS1 P48651 Phosphatidylserine synthase 1 chr8 GO:0006575 Not Cancer Driver No 81 0.171 44 7 0.159 3
PTDSS2 PTDSS2 Q9BVG9 Phosphatidylserine synthase 2 chr11 GO:0006575 Not Cancer Driver No 41 0.084 92 4 0.043 0
SARDH_ENST00000439388 SARDH Q9UL12 Sarcosine dehydrogenase, mitochondrial chr9 GO:0006575 Not Cancer Driver No 144 0.157 132 24 0.182 2
SERINC1 SERINC1 Q9NRX5 Serine incorporator 1 chr6 GO:0006575 Not Cancer Driver No 51 0.113 21 1 0.048 0
SERINC2_ENST00000373709 SERINC2 Q96SA4 Serine incorporator 2 chr1 GO:0006575 Not Cancer Driver No 49 0.108 6 0 0.0 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:0006575 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERINC5_ENST00000509193 SERINC5 Q86VE9 Serine incorporator 5 chr5 GO:0006575 Not Cancer Driver No 38 0.09 13 1 0.077 0
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 GO:0006575 Not Cancer Driver No 51 0.106 32 7 0.219 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 GO:0006575 Not Cancer Driver No 57 0.113 58 5 0.086 1
SLC16A10 SLC16A10 Q8TF71 Monocarboxylate transporter 10 chr6 GO:0006575 Not Cancer Driver No 57 0.111 82 2 0.024 0
SLC16A2 SLC16A2 P36021 Monocarboxylate transporter 8 chrX GO:0006575 Not Cancer Driver No 84 0.156 124 12 0.097 20
SLC19A1 SLC19A1 P41440 Reduced folate transporter chr21 GO:0006575 Not Cancer Driver No 77 0.13 144 7 0.049 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0006575 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0006575 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC22A4 SLC22A4 Q9H015 Solute carrier family 22 member 4 chr5 GO:0006575 Not Cancer Driver No 57 0.103 8 2 0.25 0
SLC25A32 SLC25A32 Q9H2D1 Mitochondrial folate transporter/carrier chr8 GO:0006575 Not Cancer Driver No 45 0.143 4 0 0.0 1
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0006575 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC46A1 SLC46A1 Q96NT5 Proton-coupled folate transporter chr17 GO:0006575 Not Cancer Driver No 37 0.081 31 0 0.0 13
SLC5A5 SLC5A5 Q92911 Sodium/iodide cotransporter chr19 GO:0006575 Not Cancer Driver No 96 0.149 59 7 0.119 5
SLC6A8 SLC6A8 P48029 Sodium- and chloride-dependent creatine transporter 1 chrX GO:0006575 Not Cancer Driver No 50 0.079 25 1 0.04 12
SULT1B1 SULT1B1 O43704 Sulfotransferase 1B1 chr4 GO:0006575 Not Cancer Driver No 82 0.277 15 7 0.467 0
SULT2A1 SULT2A1 Q06520 Sulfotransferase 2A1 chr19 GO:0006575 Not Cancer Driver No 50 0.175 0 0 0.0 0
TG TG P01266 Thyroglobulin chr8 GO:0006575 Not Cancer Driver No 620 0.224 276 73 0.264 7
TMLHE TMLHE Q9NVH6 Trimethyllysine dioxygenase, mitochondrial chrX GO:0006575 Not Cancer Driver No 49 0.116 4 0 0.0 1
TPO TPO P07202 Thyroid peroxidase chr2 GO:0006575 Not Cancer Driver No 326 0.349 163 69 0.423 24
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0006575 Not Cancer Driver No 22 0.07 41 0 0.0 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0006575 Not Cancer Driver No 88 0.172 20 5 0.25 0
VNN2 VNN2 O95498 Pantetheine hydrolase VNN2 chr6 GO:0006575 Not Cancer Driver No 96 0.185 15 3 0.2 0