Total number of protein in "GO:0006518" GO term: 99
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA7 | ABCA7 | Q8IZY2 | Phospholipid-transporting ATPase ABCA7 | chr19 | GO:0006518 | Not Cancer Driver | No | 260 | 0.121 | 402 | 35 | 0.087 | 1 |
| ABCB9 | ABCB9 | Q9NP78 | ABC-type oligopeptide transporter ABCB9 | chr12 | GO:0006518 | Not Cancer Driver | No | 80 | 0.104 | 49 | 1 | 0.02 | 0 |
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0006518 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ACE2 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | GO:0006518 | Not Cancer Driver | No | 104 | 0.129 | 68 | 5 | 0.074 | 0 |
| ADAMTS13 | ADAMTS13 | Q76LX8 | A disintegrin and metalloproteinase with thrombospondin motifs 13 | chr9 | GO:0006518 | Not Cancer Driver | No | 172 | 0.121 | 285 | 35 | 0.123 | 43 |
| AEBP1 | AEBP1 | Q8IUX7 | Adipocyte enhancer-binding protein 1 | chr7 | GO:0006518 | Not Cancer Driver | No | 175 | 0.151 | 689 | 102 | 0.148 | 0 |
| ANPEP | ANPEP | P15144 | Aminopeptidase N | chr15 | GO:0006518 | Not Cancer Driver | No | 175 | 0.181 | 109 | 26 | 0.239 | 0 |
| APEH | APEH | P13798 | Acylamino-acid-releasing enzyme | chr3 | GO:0006518 | Not Cancer Driver | No | 76 | 0.104 | 98 | 6 | 0.061 | 0 |
| APH1A | APH1A | Q96BI3 | Gamma-secretase subunit APH-1A | chr1 | GO:0006518 | Not Cancer Driver | No | 32 | 0.121 | 0 | 0 | 0.0 | 0 |
| APH1B | APH1B | Q8WW43 | Gamma-secretase subunit APH-1B | chr15 | GO:0006518 | Not Cancer Driver | No | 21 | 0.082 | 0 | 0 | 0.0 | 0 |
| ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | GO:0006518 | Not Cancer Driver | No | 56 | 0.16 | 0 | 0 | 0.0 | 2 |
| BACE1 | BACE1 | P56817 | Beta-secretase 1 | chr11 | GO:0006518 | Not Cancer Driver | No | 55 | 0.11 | 53 | 5 | 0.094 | 0 |
| BACE2 | BACE2 | Q9Y5Z0 | Beta-secretase 2 | chr21 | GO:0006518 | Not Cancer Driver | No | 61 | 0.118 | 23 | 2 | 0.087 | 0 |
| BCHE | BCHE | P06276 | Cholinesterase | chr3 | GO:0006518 | Not Cancer Driver | No | 185 | 0.307 | 14 | 4 | 0.286 | 38 |
| BDH2 | BDH2 | Q9BUT1 | 3-hydroxybutyrate dehydrogenase type 2 | chr4 | GO:0006518 | Not Cancer Driver | No | 24 | 0.098 | 22 | 1 | 0.045 | 0 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0006518 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| CARNMT1 | CARNMT1 | Q8N4J0 | Carnosine N-methyltransferase | chr9 | GO:0006518 | Not Cancer Driver | No | 42 | 0.103 | 75 | 1 | 0.013 | 0 |
| CARNS1_ENST00000307823 | CARNS1 | A5YM72 | Carnosine synthase 1 | chr11 | GO:0006518 | Not Cancer Driver | No | 74 | 0.089 | 42 | 4 | 0.095 | 0 |
| CHAC1_ENST00000617961 | CHAC1 | Q9BUX1 | Glutathione-specific gamma-glutamylcyclotransferase 1 | chr15 | GO:0006518 | Not Cancer Driver | No | 30 | 0.135 | 49 | 5 | 0.102 | 0 |
| CHAC2 | CHAC2 | Q8WUX2 | Glutathione-specific gamma-glutamylcyclotransferase 2 | chr2 | GO:0006518 | Not Cancer Driver | No | 21 | 0.114 | 11 | 2 | 0.182 | 0 |
| CMA1 | CMA1 | P23946 | Chymase | chr14 | GO:0006518 | Not Cancer Driver | No | 47 | 0.19 | 9 | 1 | 0.111 | 0 |
| CORIN | CORIN | Q9Y5Q5 | Atrial natriuretic peptide-converting enzyme | chr4 | GO:0006518 | Not Cancer Driver | No | 208 | 0.2 | 60 | 13 | 0.217 | 2 |
| CPA3 | CPA3 | P15088 | Mast cell carboxypeptidase A | chr3 | GO:0006518 | Not Cancer Driver | No | 111 | 0.266 | 38 | 9 | 0.237 | 0 |
| CPD | CPD | O75976 | Carboxypeptidase D | chr17 | GO:0006518 | Not Cancer Driver | No | 131 | 0.095 | 476 | 45 | 0.095 | 0 |
| CPE | CPE | P16870 | Carboxypeptidase E | chr4 | GO:0006518 | Not Cancer Driver | No | 98 | 0.206 | 127 | 24 | 0.189 | 0 |
| CPM | CPM | P14384 | Carboxypeptidase M | chr12 | GO:0006518 | Not Cancer Driver | No | 65 | 0.147 | 16 | 2 | 0.125 | 0 |
| CPN1 | CPN1 | P15169 | Carboxypeptidase N catalytic chain | chr10 | GO:0006518 | Not Cancer Driver | No | 98 | 0.214 | 124 | 27 | 0.218 | 1 |
| CPQ | CPQ | Q9Y646 | Carboxypeptidase Q | chr8 | GO:0006518 | Not Cancer Driver | No | 110 | 0.233 | 3 | 0 | 0.0 | 0 |
| CPXM1 | CPXM1 | Q96SM3 | Probable carboxypeptidase X1 | chr20 | GO:0006518 | Not Cancer Driver | No | 128 | 0.174 | 252 | 35 | 0.139 | 0 |
| CPXM2 | CPXM2 | Q8N436 | Inactive carboxypeptidase-like protein X2 | chr10 | GO:0006518 | Not Cancer Driver | No | 198 | 0.262 | 259 | 64 | 0.247 | 0 |
| CPZ | CPZ | Q66K79 | Carboxypeptidase Z | chr4 | GO:0006518 | Not Cancer Driver | No | 163 | 0.25 | 71 | 31 | 0.437 | 0 |
| CTSG | CTSG | P08311 | Cathepsin G | chr14 | GO:0006518 | Not Cancer Driver | No | 65 | 0.255 | 80 | 29 | 0.362 | 0 |
| CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0006518 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
| CTSL | CTSL | P07711 | Procathepsin L | chr9 | GO:0006518 | Not Cancer Driver | No | 47 | 0.141 | 34 | 4 | 0.118 | 0 |
| CTSZ | CTSZ | Q9UBR2 | Cathepsin Z | chr20 | GO:0006518 | Not Cancer Driver | No | 30 | 0.099 | 10 | 0 | 0.0 | 0 |
| DISP1 | DISP1 | Q96F81 | Protein dispatched homolog 1 | chr1 | GO:0006518 | Not Cancer Driver | No | 212 | 0.139 | 252 | 35 | 0.139 | 0 |
| DNPEP_ENST00000273075 | DNPEP | Q9ULA0 | Aspartyl aminopeptidase | chr2 | GO:0006518 | Not Cancer Driver | No | 55 | 0.113 | 90 | 8 | 0.089 | 0 |
| DPEP1 | DPEP1 | P16444 | Dipeptidase 1 | chr16 | GO:0006518 | Not Cancer Driver | No | 54 | 0.131 | 41 | 6 | 0.146 | 0 |
| DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | GO:0006518 | Not Cancer Driver | No | 151 | 0.197 | 8 | 1 | 0.125 | 0 |
| DYRK1A_ENST00000644942 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | GO:0006518 | Not Cancer Driver | No | 135 | 0.177 | 447 | 73 | 0.163 | 0 |
| ECE1 | ECE1 | P42892 | Endothelin-converting enzyme 1 | chr1 | GO:0006518 | Not Cancer Driver | No | 118 | 0.153 | 99 | 26 | 0.263 | 1 |
| ECE2 | ECE2 | P0DPD6 | Endothelin-converting enzyme 2 | chr3 | GO:0006518 | Not Cancer Driver | No | 178 | 0.219 | 149 | 40 | 0.268 | 0 |
| ELANE_ENST00000263621 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0006518 | Not Cancer Driver | No | 39 | 0.146 | 18 | 3 | 0.167 | 89 |
| ENPEP | ENPEP | Q07075 | Glutamyl aminopeptidase | chr4 | GO:0006518 | Compendium | Yes | 235 | 0.246 | 130 | 44 | 0.338 | 0 |
| ERAP1_ENST00000443439 | ERAP1 | Q9NZ08 | Endoplasmic reticulum aminopeptidase 1 | chr5 | GO:0006518 | Not Cancer Driver | No | 78 | 0.083 | 70 | 2 | 0.029 | 0 |
| ERAP2 | ERAP2 | Q6P179 | Endoplasmic reticulum aminopeptidase 2 | chr5 | GO:0006518 | Not Cancer Driver | No | 97 | 0.101 | 23 | 4 | 0.174 | 0 |
| ERO1A | ERO1A | Q96HE7 | ERO1-like protein alpha | chr14 | GO:0006518 | Not Cancer Driver | No | 48 | 0.103 | 32 | 5 | 0.156 | 0 |
| FURIN_ENST00000610579 | FURIN | P09958 | Furin | chr15 | GO:0006518 | Not Cancer Driver | No | 93 | 0.117 | 283 | 35 | 0.124 | 0 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0006518 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GCLM | GCLM | P48507 | Glutamate--cysteine ligase regulatory subunit | chr1 | GO:0006518 | Not Cancer Driver | No | 32 | 0.117 | 31 | 3 | 0.097 | 0 |
| GGT1_ENST00000248923 | GGT1 | P19440 | Glutathione hydrolase 1 proenzyme | chr22 | GO:0006518 | Not Cancer Driver | No | 83 | 0.146 | 88 | 14 | 0.159 | 0 |
| GGT2 | GGT2P | P36268 | Inactive glutathione hydrolase 2 | chr22 | GO:0006518 | Not Cancer Driver | No | 5 | 0.009 | 48 | 1 | 0.021 | 0 |
| GGT5_ENST00000327365 | GGT5 | P36269 | Glutathione hydrolase 5 proenzyme | chr22 | GO:0006518 | Not Cancer Driver | No | 99 | 0.169 | 122 | 27 | 0.221 | 0 |
| GGT6_ENST00000574154 | GGT6 | Q6P531 | Glutathione hydrolase 6 | chr17 | GO:0006518 | Not Cancer Driver | No | 51 | 0.103 | 211 | 32 | 0.152 | 0 |
| GGT7 | GGT7 | Q9UJ14 | Glutathione hydrolase 7 | chr20 | GO:0006518 | Not Cancer Driver | No | 77 | 0.116 | 170 | 14 | 0.082 | 0 |
| GGTLC1_ENST00000278765 | GGTLC1 | Q9BX51 | Glutathione hydrolase light chain 1 | chr20 | GO:0006518 | Not Cancer Driver | No | 63 | 0.28 | 81 | 17 | 0.21 | 0 |
| GGTLC2 | GGTLC2 | Q14390 | Glutathione hydrolase light chain 2 | chr22 | GO:0006518 | Not Cancer Driver | No | 25 | 0.115 | 119 | 11 | 0.092 | 0 |
| GSS_ENST00000216951 | GSS | P48637 | Glutathione synthetase | chr20 | GO:0006518 | Not Cancer Driver | No | 61 | 0.129 | 49 | 6 | 0.122 | 14 |
| HAGH | HAGH | Q16775 | Hydroxyacylglutathione hydrolase, mitochondrial | chr16 | GO:0006518 | Not Cancer Driver | No | 26 | 0.084 | 41 | 1 | 0.024 | 0 |
| IDE | IDE | P14735 | Insulin-degrading enzyme | chr10 | GO:0006518 | Not Cancer Driver | No | 90 | 0.088 | 96 | 8 | 0.083 | 0 |
| LNPEP | LNPEP | Q9UIQ6 | Leucyl-cystinyl aminopeptidase | chr5 | GO:0006518 | Not Cancer Driver | No | 115 | 0.112 | 103 | 8 | 0.078 | 0 |
| LTA4H | LTA4H | P09960 | Leukotriene A-4 hydrolase | chr12 | GO:0006518 | Not Cancer Driver | No | 59 | 0.097 | 39 | 6 | 0.154 | 0 |
| LVRN | LVRN | Q6Q4G3 | Aminopeptidase Q | chr5 | GO:0006518 | Not Cancer Driver | No | 212 | 0.214 | 81 | 20 | 0.247 | 0 |
| MBOAT4 | MBOAT4 | Q96T53 | Ghrelin O-acyltransferase | chr8 | GO:0006518 | Not Cancer Driver | No | 23 | 0.053 | 0 | 0 | 0.0 | 0 |
| MGAT3 | MGAT3 | Q09327 | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase | chr22 | GO:0006518 | Not Cancer Driver | No | 105 | 0.197 | 130 | 27 | 0.208 | 0 |
| MGST2 | MGST2 | Q99735 | Microsomal glutathione S-transferase 2 | chr4 | GO:0006518 | Not Cancer Driver | No | 11 | 0.075 | 0 | 0 | 0.0 | 0 |
| MIPEP | MIPEP | Q99797 | Mitochondrial intermediate peptidase | chr13 | GO:0006518 | Not Cancer Driver | No | 77 | 0.108 | 40 | 2 | 0.05 | 3 |
| MME_ENST00000492661 | MME | P08473 | Neprilysin | chr3 | GO:0006518 | Not Cancer Driver | No | 189 | 0.252 | 40 | 17 | 0.425 | 4 |
| NAALADL1 | NAALADL1 | Q9UQQ1 | Aminopeptidase NAALADL1 | chr11 | GO:0006518 | Not Cancer Driver | No | 105 | 0.142 | 135 | 17 | 0.126 | 0 |
| NAT8 | NAT8 | Q9UHE5 | N-acetyltransferase 8 | chr2 | GO:0006518 | Not Cancer Driver | No | 48 | 0.211 | 0 | 0 | 0.0 | 0 |
| NCSTN | NCSTN | Q92542 | Nicastrin | chr1 | GO:0006518 | Not Cancer Driver | No | 94 | 0.133 | 72 | 11 | 0.153 | 1 |
| NLN | NLN | Q9BYT8 | Neurolysin, mitochondrial | chr5 | GO:0006518 | Not Cancer Driver | No | 70 | 0.099 | 25 | 3 | 0.12 | 0 |
| NPEPPS | NPEPPS | P55786 | Puromycin-sensitive aminopeptidase | chr17 | GO:0006518 | Compendium | Yes | 102 | 0.111 | 45 | 5 | 0.111 | 0 |
| PAM_ENST00000438793 | PAM | P19021 | Peptidyl-glycine alpha-amidating monooxygenase | chr5 | GO:0006518 | Not Cancer Driver | No | 129 | 0.133 | 254 | 37 | 0.146 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0006518 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PCSK1 | PCSK1 | P29120 | Neuroendocrine convertase 1 | chr5 | GO:0006518 | Not Cancer Driver | No | 139 | 0.185 | 336 | 61 | 0.182 | 2 |
| PCSK1N | PCSK1N | Q9UHG2 | ProSAAS | chrX | GO:0006518 | Not Cancer Driver | No | 7 | 0.027 | 187 | 7 | 0.037 | 0 |
| PCSK2 | PCSK2 | P16519 | Neuroendocrine convertase 2 | chr20 | GO:0006518 | Not Cancer Driver | No | 144 | 0.226 | 153 | 39 | 0.255 | 0 |
| PCSK4 | PCSK4 | Q6UW60 | Proprotein convertase subtilisin/kexin type 4 | chr19 | GO:0006518 | Not Cancer Driver | No | 83 | 0.11 | 149 | 20 | 0.134 | 0 |
| PCSK5 | PCSK5 | Q92824 | Proprotein convertase subtilisin/kexin type 5 | chr9 | GO:0006518 | Not Cancer Driver | No | 319 | 0.172 | 168 | 25 | 0.149 | 0 |
| PCSK6 | PCSK6 | P29122 | Proprotein convertase subtilisin/kexin type 6 | chr15 | GO:0006518 | Not Cancer Driver | No | 138 | 0.142 | 207 | 45 | 0.217 | 0 |
| PCSK7 | PCSK7 | Q16549 | Proprotein convertase subtilisin/kexin type 7 | chr11 | GO:0006518 | Not Cancer Driver | No | 101 | 0.129 | 262 | 31 | 0.118 | 0 |
| PGLYRP2 | PGLYRP2 | Q96PD5 | N-acetylmuramoyl-L-alanine amidase | chr19 | GO:0006518 | Not Cancer Driver | No | 111 | 0.193 | 160 | 28 | 0.175 | 0 |
| PLA2G7 | PLA2G7 | Q13093 | Platelet-activating factor acetylhydrolase | chr6 | GO:0006518 | Not Cancer Driver | No | 70 | 0.159 | 27 | 7 | 0.259 | 2 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0006518 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
| PSEN2 | PSEN2 | P49810 | Presenilin-2 | chr1 | GO:0006518 | Not Cancer Driver | No | 68 | 0.152 | 89 | 16 | 0.18 | 7 |
| PSENEN_ENST00000222266 | PSENEN | Q9NZ42 | Gamma-secretase subunit PEN-2 | chr19 | GO:0006518 | Not Cancer Driver | No | 17 | 0.168 | 0 | 0 | 0.0 | 0 |
| REN | REN | P00797 | Renin | chr1 | GO:0006518 | Not Cancer Driver | No | 60 | 0.148 | 10 | 0 | 0.0 | 3 |
| SCG5 | SCG5 | P05408 | Neuroendocrine protein 7B2 | chr15 | GO:0006518 | Not Cancer Driver | No | 25 | 0.118 | 174 | 21 | 0.121 | 0 |
| SLC1A1 | SLC1A1 | P43005 | Excitatory amino acid transporter 3 | chr9 | GO:0006518 | Not Cancer Driver | No | 69 | 0.132 | 17 | 4 | 0.235 | 1 |
| SLC1A2 | SLC1A2 | P43004 | Excitatory amino acid transporter 2 | chr11 | GO:0006518 | Not Cancer Driver | No | 77 | 0.134 | 81 | 7 | 0.086 | 3 |
| SLC30A5 | SLC30A5 | Q8TAD4 | Zinc transporter 5 | chr5 | GO:0006518 | Not Cancer Driver | No | 58 | 0.076 | 33 | 0 | 0.0 | 0 |
| SLC30A6_ENST00000282587 | SLC30A6 | Q6NXT4 | Zinc transporter 6 | chr2 | GO:0006518 | Not Cancer Driver | No | 54 | 0.117 | 93 | 7 | 0.075 | 0 |
| SLC30A8 | SLC30A8 | Q8IWU4 | Zinc transporter 8 | chr8 | GO:0006518 | Not Cancer Driver | No | 115 | 0.312 | 25 | 9 | 0.36 | 0 |
| TAPBP_ENST00000434618 | TAPBP | O15533 | Tapasin | chr6 | GO:0006518 | Not Cancer Driver | No | 58 | 0.129 | 168 | 26 | 0.155 | 0 |
| THOP1 | THOP1 | P52888 | Thimet oligopeptidase | chr19 | GO:0006518 | Not Cancer Driver | No | 90 | 0.131 | 91 | 12 | 0.132 | 0 |
| TPP1 | TPP1 | O14773 | Tripeptidyl-peptidase 1 | chr11 | GO:0006518 | Not Cancer Driver | No | 67 | 0.119 | 92 | 7 | 0.076 | 37 |
| TRHDE | TRHDE | Q9UKU6 | Thyrotropin-releasing hormone-degrading ectoenzyme | chr12 | GO:0006518 | Not Cancer Driver | No | 346 | 0.338 | 104 | 11 | 0.106 | 0 |
| YIPF5 | YIPF5 | Q969M3 | Protein YIPF5 | chr5 | GO:0006518 | Not Cancer Driver | No | 23 | 0.089 | 57 | 6 | 0.105 | 1 |