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Total number of protein in "GO:0006511" GO term:  269

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADRM1 ADRM1 Q16186 Proteasomal ubiquitin receptor ADRM1 chr20 GO:0006511 Not Cancer Driver No 49 0.12 296 40 0.135 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0006511 Not Cancer Driver No 73 0.114 229 30 0.131 0
ANAPC1 ANAPC1 Q9H1A4 Anaphase-promoting complex subunit 1 chr2 GO:0006511 Not Cancer Driver No 206 0.106 263 33 0.125 0
ANAPC11_ENST00000579978 ANAPC11 Q9NYG5 Anaphase-promoting complex subunit 11 chr17 GO:0006511 Not Cancer Driver No 7 0.083 0 0 0.0 0
ANAPC4_ENST00000315368 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 GO:0006511 Not Cancer Driver No 70 0.087 54 1 0.019 0
ANAPC5 ANAPC5 Q9UJX4 Anaphase-promoting complex subunit 5 chr12 GO:0006511 Not Cancer Driver No 94 0.125 41 4 0.098 0
ANKIB1 ANKIB1 Q9P2G1 Ankyrin repeat and IBR domain-containing protein 1 chr7 GO:0006511 Not Cancer Driver No 141 0.129 577 78 0.135 0
AREL1 AREL1 O15033 Apoptosis-resistant E3 ubiquitin protein ligase 1 chr14 GO:0006511 Not Cancer Driver No 104 0.126 92 10 0.109 0
ARIH1 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 GO:0006511 Not Cancer Driver No 46 0.083 119 7 0.059 0
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 GO:0006511 Not Cancer Driver No 64 0.13 85 11 0.129 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0006511 Not Cancer Driver No 49 0.117 154 13 0.084 0
ARRDC1 ARRDC1 Q8N5I2 Arrestin domain-containing protein 1 chr9 GO:0006511 Not Cancer Driver No 39 0.09 141 11 0.078 0
ASB2 ASB2 Q96Q27 Ankyrin repeat and SOCS box protein 2 chr14 GO:0006511 Not Cancer Driver No 90 0.142 167 19 0.114 0
ASCC2 ASCC2 Q9H1I8 Activating signal cointegrator 1 complex subunit 2 chr22 GO:0006511 Not Cancer Driver No 87 0.115 326 34 0.104 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 GO:0006511 Not Cancer Driver No 279 0.127 87 8 0.092 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0006511 Not Cancer Driver No 46 0.127 181 24 0.133 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0006511 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 GO:0006511 Census, Compendium Yes 141 0.193 418 59 0.141 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 GO:0006511 Not Cancer Driver No 56 0.124 30 1 0.033 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0006511 Not Cancer Driver No 80 0.132 45 4 0.089 0
C18orf25 C18orf25 Q96B23 Uncharacterized protein C18orf25 chr18 GO:0006511 Not Cancer Driver No 30 0.074 393 27 0.069 0
C2orf40 ECRG4 Q9H1Z8 Augurin chr2 GO:0006511 Not Cancer Driver No 37 0.25 23 11 0.478 0
CACUL1 CACUL1 Q86Y37 CDK2-associated and cullin domain-containing protein 1 chr10 GO:0006511 Not Cancer Driver No 35 0.095 128 6 0.047 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0006511 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBLC_ENST00000647358 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 GO:0006511 Census Yes 60 0.127 128 21 0.164 0
CDC16_ENST00000356221 CDC16 Q13042 Cell division cycle protein 16 homolog chr13 GO:0006511 Not Cancer Driver No 68 0.11 54 7 0.13 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0006511 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0006511 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDC23 CDC23 Q9UJX2 Cell division cycle protein 23 homolog chr5 GO:0006511 Not Cancer Driver No 57 0.095 45 6 0.133 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 GO:0006511 Not Cancer Driver No 179 0.217 289 75 0.26 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0006511 Not Cancer Driver No 26 0.11 95 11 0.116 0
CHFR CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 GO:0006511 Not Cancer Driver No 85 0.128 341 54 0.158 0
CNOT4_ENST00000315544 CNOT4 O95628 CCR4-NOT transcription complex subunit 4 chr7 GO:0006511 Not Cancer Driver No 73 0.127 359 35 0.097 0
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 GO:0006511 Not Cancer Driver No 55 0.13 67 10 0.149 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0006511 Census, Compendium Yes 123 0.16 167 23 0.138 3
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:0006511 Not Cancer Driver No 188 0.111 372 41 0.11 3
CUL9 CUL9 Q8IWT3 Cullin-9 chr6 GO:0006511 Not Cancer Driver No 321 0.128 633 73 0.115 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0006511 Census, Compendium Yes 116 0.121 213 31 0.146 3
DCAF12 DCAF12 Q5T6F0 DDB1- and CUL4-associated factor 12 chr9 GO:0006511 Not Cancer Driver No 59 0.13 70 7 0.1 0
DCST1 DCST1 Q5T197 E3 ubiquitin-protein ligase DCST1 chr1 GO:0006511 Not Cancer Driver No 108 0.153 51 9 0.176 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0006511 Not Cancer Driver No 126 0.111 50 8 0.16 4
DTL DTL Q9NZJ0 Denticleless protein homolog chr1 GO:0006511 Not Cancer Driver No 73 0.1 331 49 0.148 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0006511 Not Cancer Driver No 86 0.116 260 24 0.092 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 GO:0006511 Not Cancer Driver No 54 0.082 141 5 0.035 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 GO:0006511 Not Cancer Driver No 69 0.119 54 3 0.056 0
ELOC ELOC Q15369 Elongin-C chr8 GO:0006511 Not Cancer Driver No 22 0.196 25 5 0.2 0
FBXL14 FBXL14 Q8N1E6 F-box/LRR-repeat protein 14 chr12 GO:0006511 Not Cancer Driver No 33 0.079 7 1 0.143 0
FBXL4_ENST00000229971 FBXL4 Q9UKA2 F-box/LRR-repeat protein 4 chr6 GO:0006511 Not Cancer Driver No 82 0.132 23 2 0.087 7
FBXL7 FBXL7 Q9UJT9 F-box/LRR-repeat protein 7 chr5 GO:0006511 Not Cancer Driver No 199 0.405 117 33 0.282 0
FBXO10 FBXO10 Q9UK96 F-box only protein 10 chr9 GO:0006511 Not Cancer Driver No 106 0.111 223 23 0.103 0
FBXO11 FBXO11 Q86XK2 F-box only protein 11 chr2 GO:0006511 Census, Compendium Yes 113 0.122 242 22 0.091 8
FBXO21 FBXO21 O94952 F-box only protein 21 chr12 GO:0006511 Not Cancer Driver No 73 0.116 17 3 0.176 0
FBXO22 FBXO22 Q8NEZ5 F-box only protein 22 chr15 GO:0006511 Not Cancer Driver No 65 0.161 15 3 0.2 0
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0006511 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO45 FBXO45 P0C2W1 F-box/SPRY domain-containing protein 1 chr3 GO:0006511 Not Cancer Driver No 28 0.098 10 0 0.0 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0006511 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXO8 FBXO8 Q9NRD0 F-box only protein 8 chr4 GO:0006511 Not Cancer Driver No 46 0.144 25 1 0.04 0
FBXW4 FBXW4 P57775 F-box/WD repeat-containing protein 4 chr10 GO:0006511 Not Cancer Driver No 36 0.087 21 0 0.0 0
FEM1A FEM1A Q9BSK4 Protein fem-1 homolog A chr19 GO:0006511 Not Cancer Driver No 68 0.102 162 22 0.136 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0006511 Not Cancer Driver No 69 0.11 33 3 0.091 0
FEM1C FEM1C Q96JP0 Protein fem-1 homolog C chr5 GO:0006511 Not Cancer Driver No 55 0.089 27 1 0.037 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0006511 Not Cancer Driver No 74 0.149 184 30 0.163 0
GET4 GET4 Q7L5D6 Golgi to ER traffic protein 4 homolog chr7 GO:0006511 Not Cancer Driver No 34 0.104 51 3 0.059 0
HACE1 HACE1 Q8IYU2 E3 ubiquitin-protein ligase HACE1 chr6 GO:0006511 Not Cancer Driver No 126 0.139 103 12 0.117 0
HERC3 HERC3 Q15034 Probable E3 ubiquitin-protein ligase HERC3 chr4 GO:0006511 Not Cancer Driver No 112 0.107 56 7 0.125 0
HERC4 HERC4 Q5GLZ8 Probable E3 ubiquitin-protein ligase HERC4 chr10 GO:0006511 Not Cancer Driver No 111 0.105 40 2 0.05 0
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 GO:0006511 Not Cancer Driver No 124 0.121 118 12 0.102 0
HERC6 HERC6 Q8IVU3 Probable E3 ubiquitin-protein ligase HERC6 chr4 GO:0006511 Not Cancer Driver No 146 0.143 132 16 0.121 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0006511 Census Yes 38 0.097 248 17 0.069 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0006511 Not Cancer Driver No 95 0.105 335 42 0.125 0
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 GO:0006511 Not Cancer Driver No 68 0.217 73 19 0.26 0
KCTD21 KCTD21 Q4G0X4 BTB/POZ domain-containing protein KCTD21 chr11 GO:0006511 Not Cancer Driver No 40 0.154 11 0 0.0 0
KCTD6_ENST00000490264 KCTD6 Q8NC69 BTB/POZ domain-containing protein KCTD6 chr3 GO:0006511 Not Cancer Driver No 27 0.114 12 1 0.083 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:0006511 Census, Compendium Yes 237 0.38 57 12 0.211 0
KLHDC1 KLHDC1 Q8N7A1 Kelch domain-containing protein 1 chr14 GO:0006511 Not Cancer Driver No 36 0.089 37 7 0.189 0
KLHDC10 KLHDC10 Q6PID8 Kelch domain-containing protein 10 chr7 GO:0006511 Not Cancer Driver No 40 0.09 93 3 0.032 0
KLHDC2 KLHDC2 Q9Y2U9 Kelch domain-containing protein 2 chr14 GO:0006511 Not Cancer Driver No 39 0.096 42 2 0.048 0
KLHDC3 KLHDC3 Q9BQ90 Kelch domain-containing protein 3 chr6 GO:0006511 Not Cancer Driver No 43 0.113 12 1 0.083 0
KLHL15 KLHL15 Q96M94 Kelch-like protein 15 chrX GO:0006511 Not Cancer Driver No 74 0.123 25 4 0.16 0
KLHL25 KLHL25 Q9H0H3 Kelch-like protein 25 chr15 GO:0006511 Not Cancer Driver No 83 0.141 32 7 0.219 0
KLHL3 KLHL3 Q9UH77 Kelch-like protein 3 chr5 GO:0006511 Not Cancer Driver No 67 0.114 34 9 0.265 32
KLHL8 KLHL8 Q9P2G9 Kelch-like protein 8 chr4 GO:0006511 Not Cancer Driver No 75 0.121 63 7 0.111 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 GO:0006511 Not Cancer Driver No 117 0.161 261 40 0.153 0
LTN1_ENST00000361371 LTN1 O94822 E3 ubiquitin-protein ligase listerin chr21 GO:0006511 Not Cancer Driver No 192 0.109 124 23 0.185 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0006511 Census, Compendium Yes 56 0.114 297 37 0.125 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 GO:0006511 Not Cancer Driver No 122 0.121 282 34 0.121 1
MYLIP MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 GO:0006511 Not Cancer Driver No 56 0.126 11 2 0.182 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0006511 Not Cancer Driver No 22 0.1 44 4 0.091 0
NDFIP2_ENST00000218652 NDFIP2 Q9NV92 NEDD4 family-interacting protein 2 chr13 GO:0006511 Not Cancer Driver No 27 0.08 198 13 0.066 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0006511 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0006511 Not Cancer Driver No 126 0.129 463 60 0.13 4
NEDD8 NEDD8 Q15843 NEDD8 chr14 GO:0006511 Not Cancer Driver No 10 0.123 36 5 0.139 0
NEMF NEMF O60524 Ribosome quality control complex subunit NEMF chr14 GO:0006511 Not Cancer Driver No 109 0.101 517 61 0.118 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 GO:0006511 Not Cancer Driver No 78 0.128 47 8 0.17 0
NTAN1 NTAN1 Q96AB6 Protein N-terminal asparagine amidohydrolase chr16 GO:0006511 Not Cancer Driver No 27 0.087 87 6 0.069 0
NUB1_ENST00000470229 NUB1 Q9Y5A7 NEDD8 ultimate buster 1 chr7 GO:0006511 Not Cancer Driver No 52 0.085 180 15 0.083 0
OS9 OS9 Q13438 Protein OS-9 chr12 GO:0006511 Not Cancer Driver No 72 0.108 451 49 0.109 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0006511 Not Cancer Driver No 57 0.098 99 13 0.131 23
PPP1R11 PPP1R11 O60927 E3 ubiquitin-protein ligase PPP1R11 chr6 GO:0006511 Not Cancer Driver No 17 0.135 126 17 0.135 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0006511 Not Cancer Driver No 110 0.237 78 15 0.192 31
PSMA8 PSMA8 Q8TAA3 Proteasome subunit alpha-type 8 chr18 GO:0006511 Not Cancer Driver No 42 0.164 15 5 0.333 0
PSMC2_ENST00000292644 PSMC2 P35998 26S proteasome regulatory subunit 7 chr7 GO:0006511 Not Cancer Driver No 63 0.145 120 13 0.108 0
PSMD11_ENST00000457654 PSMD11 O00231 26S proteasome non-ATPase regulatory subunit 11 chr17 GO:0006511 Not Cancer Driver No 51 0.121 0 0 0.0 0
PSMD13_ENST00000532097 PSMD13 Q9UNM6 26S proteasome non-ATPase regulatory subunit 13 chr11 GO:0006511 Not Cancer Driver No 30 0.08 13 3 0.231 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 GO:0006511 Not Cancer Driver No 23 0.074 67 6 0.09 0
PSMD3 PSMD3 O43242 26S proteasome non-ATPase regulatory subunit 3 chr17 GO:0006511 Not Cancer Driver No 69 0.129 152 19 0.125 0
PSMD9 PSMD9 O00233 26S proteasome non-ATPase regulatory subunit 9 chr12 GO:0006511 Not Cancer Driver No 22 0.099 173 16 0.092 0
PSMF1_ENST00000333082 PSMF1 Q92530 Proteasome inhibitor PI31 subunit chr20 GO:0006511 Not Cancer Driver No 45 0.166 140 26 0.186 0
RBBP6 RBBP6 Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 chr16 GO:0006511 Not Cancer Driver No 229 0.128 1626 212 0.13 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0006511 Not Cancer Driver No 10 0.093 18 1 0.056 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0006511 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0006511 Not Cancer Driver No 128 0.107 703 81 0.115 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0006511 Not Cancer Driver No 33 0.126 23 0 0.0 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:0006511 Not Cancer Driver No 50 0.138 150 21 0.14 0
RLIM_ENST00000349225 RLIM Q9NVW2 E3 ubiquitin-protein ligase RLIM chrX GO:0006511 Not Cancer Driver No 106 0.17 545 94 0.172 4
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 GO:0006511 Not Cancer Driver No 17 0.11 76 7 0.092 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0006511 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF114 RNF114 Q9Y508 E3 ubiquitin-protein ligase RNF114 chr20 GO:0006511 Not Cancer Driver No 19 0.083 14 2 0.143 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0006511 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF126 RNF126 Q9BV68 E3 ubiquitin-protein ligase RNF126 chr19 GO:0006511 Not Cancer Driver No 33 0.106 182 22 0.121 0
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX GO:0006511 Not Cancer Driver No 61 0.143 123 15 0.122 0
RNF130 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 GO:0006511 Not Cancer Driver No 45 0.107 43 5 0.116 0
RNF133 RNF133 Q8WVZ7 E3 ubiquitin-protein ligase RNF133 chr7 GO:0006511 Not Cancer Driver No 76 0.202 60 5 0.083 0
RNF13_ENST00000392894 RNF13 O43567 E3 ubiquitin-protein ligase RNF13 chr3 GO:0006511 Not Cancer Driver No 45 0.118 107 17 0.159 2
RNF14 RNF14 Q9UBS8 E3 ubiquitin-protein ligase RNF14 chr5 GO:0006511 Not Cancer Driver No 52 0.11 40 8 0.2 0
RNF144A RNF144A P50876 E3 ubiquitin-protein ligase RNF144A chr2 GO:0006511 Not Cancer Driver No 63 0.216 0 0 0.0 0
RNF144B RNF144B Q7Z419 E3 ubiquitin-protein ligase RNF144B chr6 GO:0006511 Not Cancer Driver No 32 0.106 4 1 0.25 0
RNF146 RNF146 Q9NTX7 E3 ubiquitin-protein ligase RNF146 chr6 GO:0006511 Not Cancer Driver No 37 0.103 206 24 0.117 0
RNF148 RNF148 Q8N7C7 RING finger protein 148 chr7 GO:0006511 Not Cancer Driver No 75 0.246 8 3 0.375 0
RNF149 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 GO:0006511 Not Cancer Driver No 41 0.102 102 10 0.098 0
RNF150 RNF150 Q9ULK6 RING finger protein 150 chr4 GO:0006511 Not Cancer Driver No 72 0.164 144 15 0.104 0
RNF166 RNF166 Q96A37 E3 ubiquitin-protein ligase RNF166 chr16 GO:0006511 Not Cancer Driver No 18 0.076 24 2 0.083 0
RNF167_ENST00000571816 RNF167 Q9H6Y7 E3 ubiquitin-protein ligase RNF167 chr17 GO:0006511 Not Cancer Driver No 35 0.1 102 18 0.176 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0006511 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0006511 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF19A RNF19A Q9NV58 E3 ubiquitin-protein ligase RNF19A chr8 GO:0006511 Not Cancer Driver No 112 0.134 387 55 0.142 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 GO:0006511 Not Cancer Driver No 58 0.079 344 24 0.07 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:0006511 Not Cancer Driver No 126 0.129 561 64 0.114 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 GO:0006511 Census, Compendium Yes 560 0.108 623 75 0.12 3
RNF215 RNF215 Q9Y6U7 RING finger protein 215 chr22 GO:0006511 Not Cancer Driver No 30 0.08 62 2 0.032 0
RNF217 RNF217 Q8TC41 E3 ubiquitin-protein ligase RNF217 chr6 GO:0006511 Not Cancer Driver No 70 0.129 203 13 0.064 0
RNF26 RNF26 Q9BY78 E3 ubiquitin-protein ligase RNF26 chr11 GO:0006511 Not Cancer Driver No 44 0.102 71 7 0.099 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0006511 Not Cancer Driver No 30 0.081 112 7 0.062 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0006511 Not Cancer Driver No 132 0.132 645 80 0.124 0
RNF43_ENST00000577716 RNF43 Q68DV7 E3 ubiquitin-protein ligase RNF43 chr17 GO:0006511 Census, Compendium Yes 121 0.155 437 54 0.124 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0006511 Not Cancer Driver No 17 0.094 69 3 0.043 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0006511 Compendium Yes 91 0.133 601 87 0.145 0
RNF7 RNF7 Q9UBF6 RING-box protein 2 chr3 GO:0006511 Not Cancer Driver No 17 0.15 0 0 0.0 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0006511 Not Cancer Driver No 56 0.115 226 29 0.128 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0006511 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0006511 Not Cancer Driver No 48 0.148 68 3 0.044 0
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 GO:0006511 Not Cancer Driver No 89 0.118 256 31 0.121 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0006511 Not Cancer Driver No 87 0.116 242 28 0.116 0
SPSB1_ENST00000377399 SPSB1 Q96BD6 SPRY domain-containing SOCS box protein 1 chr1 GO:0006511 Not Cancer Driver No 35 0.128 26 3 0.115 0
SPSB2_ENST00000523102 SPSB2 Q99619 SPRY domain-containing SOCS box protein 2 chr12 GO:0006511 Not Cancer Driver No 30 0.114 108 12 0.111 0
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 GO:0006511 Not Cancer Driver No 42 0.154 75 3 0.04 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0006511 Not Cancer Driver No 54 0.123 267 32 0.12 30
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0006511 Not Cancer Driver No 35 0.116 112 14 0.125 12
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0006511 Not Cancer Driver No 63 0.102 284 32 0.113 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0006511 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0006511 Not Cancer Driver No 61 0.132 219 34 0.155 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 GO:0006511 Not Cancer Driver No 38 0.139 81 12 0.148 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0006511 Not Cancer Driver No 149 0.143 795 105 0.132 0
TP53INP2 TP53INP2 Q8IXH6 Tumor protein p53-inducible nuclear protein 2 chr20 GO:0006511 Not Cancer Driver No 18 0.082 197 16 0.081 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0006511 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0006511 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM58 TRIM58 Q8NG06 E3 ubiquitin-protein ligase TRIM58 chr1 GO:0006511 Not Cancer Driver No 194 0.399 84 41 0.488 0
TRIP12_ENST00000283943 TRIP12 Q14669 E3 ubiquitin-protein ligase TRIP12 chr2 GO:0006511 Not Cancer Driver No 224 0.112 845 117 0.138 4
TRIP4 TRIP4 Q15650 Activating signal cointegrator 1 chr15 GO:0006511 Not Cancer Driver No 71 0.122 176 27 0.153 0
TRPC4AP TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 GO:0006511 Not Cancer Driver No 84 0.105 70 7 0.1 0
TTC3_ENST00000355666 TTC3 P53804 E3 ubiquitin-protein ligase TTC3 chr21 GO:0006511 Not Cancer Driver No 255 0.126 723 83 0.115 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX GO:0006511 Not Cancer Driver No 117 0.111 165 22 0.133 6
UBA6 UBA6 A0AVT1 Ubiquitin-like modifier-activating enzyme 6 chr4 GO:0006511 Not Cancer Driver No 133 0.126 90 10 0.111 0
UBD UBD O15205 Ubiquitin D chr6 GO:0006511 Not Cancer Driver No 31 0.188 8 1 0.125 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:0006511 Compendium Yes 35 0.23 67 13 0.194 2
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0006511 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0006511 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 GO:0006511 Not Cancer Driver No 13 0.088 14 0 0.0 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 GO:0006511 Compendium Yes 19 0.129 13 1 0.077 0
UBE2D4 UBE2D4 Q9Y2X8 Ubiquitin-conjugating enzyme E2 D4 chr7 GO:0006511 Not Cancer Driver No 13 0.088 21 1 0.048 0
UBE2E1 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 GO:0006511 Not Cancer Driver No 21 0.109 78 10 0.128 0
UBE2G1 UBE2G1 P62253 Ubiquitin-conjugating enzyme E2 G1 chr17 GO:0006511 Not Cancer Driver No 9 0.053 39 2 0.051 0
UBE2G2 UBE2G2 P60604 Ubiquitin-conjugating enzyme E2 G2 chr21 GO:0006511 Not Cancer Driver No 24 0.145 22 3 0.136 0
UBE2H UBE2H P62256 Ubiquitin-conjugating enzyme E2 H chr7 GO:0006511 Not Cancer Driver No 20 0.109 55 11 0.2 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:0006511 Not Cancer Driver No 16 0.101 16 3 0.188 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0006511 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0006511 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE2L5_ENST00000436446 UBE2L5 A0A1B0GUS4 Ubiquitin-conjugating enzyme E2 L5 chr13 GO:0006511 Not Cancer Driver No 1 0.006 42 0 0.0 0
UBE2L6 UBE2L6 O14933 Ubiquitin/ISG15-conjugating enzyme E2 L6 chr11 GO:0006511 Not Cancer Driver No 19 0.124 7 1 0.143 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0006511 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2R2 UBE2R2 Q712K3 Ubiquitin-conjugating enzyme E2 R2 chr9 GO:0006511 Not Cancer Driver No 28 0.118 104 15 0.144 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0006511 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBE2Z UBE2Z Q9H832 Ubiquitin-conjugating enzyme E2 Z chr17 GO:0006511 Not Cancer Driver No 27 0.076 140 10 0.071 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0006511 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBE3B_ENST00000434735 UBE3B Q7Z3V4 Ubiquitin-protein ligase E3B chr12 GO:0006511 Not Cancer Driver No 151 0.141 13 0 0.0 1
UBE3C UBE3C Q15386 Ubiquitin-protein ligase E3C chr7 GO:0006511 Not Cancer Driver No 143 0.132 65 12 0.185 0
UBE4A_ENST00000252108 UBE4A Q14139 Ubiquitin conjugation factor E4 A chr11 GO:0006511 Not Cancer Driver No 120 0.113 121 17 0.14 0
UBE4B UBE4B O95155 Ubiquitin conjugation factor E4 B chr1 GO:0006511 Not Cancer Driver No 158 0.121 434 49 0.113 0
UBL4A UBL4A P11441 Ubiquitin-like protein 4A chrX GO:0006511 Not Cancer Driver No 22 0.14 16 5 0.312 0
UBL7_ENST00000565335 UBL7 Q96S82 Ubiquitin-like protein 7 chr15 GO:0006511 Not Cancer Driver No 31 0.082 192 22 0.115 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0006511 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0006511 Not Cancer Driver No 82 0.131 581 79 0.136 8
UBQLN3 UBQLN3 Q9H347 Ubiquilin-3 chr11 GO:0006511 Not Cancer Driver No 164 0.25 441 117 0.265 0
UBQLN4 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 GO:0006511 Not Cancer Driver No 70 0.116 561 67 0.119 1
UBQLNL UBQLNL Q8IYU4 Ubiquilin-like protein chr11 GO:0006511 Not Cancer Driver No 109 0.229 286 71 0.248 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 GO:0006511 Not Cancer Driver No 170 0.097 165 15 0.091 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 GO:0006511 Not Cancer Driver No 172 0.098 228 30 0.132 0
UBR3 UBR3 Q6ZT12 E3 ubiquitin-protein ligase UBR3 chr2 GO:0006511 Not Cancer Driver No 154 0.082 339 28 0.083 0
UBR4 UBR4 Q5T4S7 E3 ubiquitin-protein ligase UBR4 chr1 GO:0006511 Not Cancer Driver No 565 0.109 1066 119 0.112 0
UCHL3 UCHL3 P15374 Ubiquitin carboxyl-terminal hydrolase isozyme L3 chr13 GO:0006511 Not Cancer Driver No 26 0.113 61 3 0.049 0
UCHL5 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 GO:0006511 Not Cancer Driver No 33 0.1 41 7 0.171 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0006511 Not Cancer Driver No 26 0.085 100 7 0.07 0
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0006511 Not Cancer Driver No 97 0.122 353 49 0.139 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 GO:0006511 Not Cancer Driver No 92 0.115 425 49 0.115 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX GO:0006511 Not Cancer Driver No 140 0.145 210 28 0.133 0
USP12 USP12 O75317 Ubiquitin carboxyl-terminal hydrolase 12 chr13 GO:0006511 Not Cancer Driver No 55 0.149 33 5 0.152 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0006511 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0006511 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0006511 Not Cancer Driver No 98 0.119 394 42 0.107 0
USP17L1 USP17L1 Q7RTZ2 Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 chr8 GO:0006511 Not Cancer Driver No 7 0.013 192 1 0.005 0
USP17L10 USP17L10 C9JJH3 Ubiquitin carboxyl-terminal hydrolase 17-like protein 10 chr4 GO:0006511 Not Cancer Driver No 1 0.002 197 0 0.0 0
USP17L18 USP17L18 D6R9N7 Ubiquitin carboxyl-terminal hydrolase 17-like protein 18 chr4 GO:0006511 Not Cancer Driver No 2 0.004 200 1 0.005 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0006511 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP17L7 USP17L7 P0C7H9 Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7 chr8 GO:0006511 Not Cancer Driver No 6 0.011 169 2 0.012 0
USP18 USP18 Q9UMW8 Ubl carboxyl-terminal hydrolase 18 chr22 GO:0006511 Not Cancer Driver No 34 0.091 29 8 0.276 0
USP1_ENST00000371146 USP1 O94782 Ubiquitin carboxyl-terminal hydrolase 1 chr1 GO:0006511 Not Cancer Driver No 63 0.08 403 30 0.074 0
USP2 USP2 O75604 Ubiquitin carboxyl-terminal hydrolase 2 chr11 GO:0006511 Not Cancer Driver No 88 0.145 213 39 0.183 0
USP20_ENST00000358355 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 GO:0006511 Not Cancer Driver No 112 0.123 295 36 0.122 0
USP21_ENST00000289865 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 GO:0006511 Not Cancer Driver No 95 0.168 230 47 0.204 0
USP22 USP22 Q9UPT9 Ubiquitin carboxyl-terminal hydrolase 22 chr17 GO:0006511 Not Cancer Driver No 64 0.122 50 1 0.02 0
USP24 USP24 Q9UPU5 Ubiquitin carboxyl-terminal hydrolase 24 chr1 GO:0006511 Not Cancer Driver No 229 0.087 430 27 0.063 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 GO:0006511 Not Cancer Driver No 135 0.128 354 55 0.155 0
USP26 USP26 Q9BXU7 Ubiquitin carboxyl-terminal hydrolase 26 chrX GO:0006511 Not Cancer Driver No 206 0.226 325 75 0.231 0
USP27X USP27X A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 chrX GO:0006511 Not Cancer Driver No 31 0.071 69 3 0.043 1
USP28 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 GO:0006511 Not Cancer Driver No 151 0.14 311 25 0.08 0
USP29_ENST00000598197 USP29 Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 chr19 GO:0006511 Not Cancer Driver No 291 0.316 432 132 0.306 0
USP3 USP3 Q9Y6I4 Ubiquitin carboxyl-terminal hydrolase 3 chr15 GO:0006511 Not Cancer Driver No 60 0.115 45 4 0.089 0
USP30 USP30 Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 chr12 GO:0006511 Not Cancer Driver No 76 0.147 136 26 0.191 0
USP31 USP31 Q70CQ4 Ubiquitin carboxyl-terminal hydrolase 31 chr16 GO:0006511 Not Cancer Driver No 191 0.141 777 105 0.135 0
USP32 USP32 Q8NFA0 Ubiquitin carboxyl-terminal hydrolase 32 chr17 GO:0006511 Not Cancer Driver No 182 0.113 401 43 0.107 0
USP33_ENST00000357428 USP33 Q8TEY7 Ubiquitin carboxyl-terminal hydrolase 33 chr1 GO:0006511 Not Cancer Driver No 138 0.146 256 48 0.188 0
USP34 USP34 Q70CQ2 Ubiquitin carboxyl-terminal hydrolase 34 chr2 GO:0006511 Not Cancer Driver No 436 0.123 725 90 0.124 0
USP35 USP35 Q9P2H5 Ubiquitin carboxyl-terminal hydrolase 35 chr11 GO:0006511 Not Cancer Driver No 116 0.114 282 49 0.174 0
USP36_ENST00000312010 USP36 Q9P275 Ubiquitin carboxyl-terminal hydrolase 36 chr17 GO:0006511 Not Cancer Driver No 151 0.134 718 91 0.127 0
USP37_ENST00000454775 USP37 Q86T82 Ubiquitin carboxyl-terminal hydrolase 37 chr2 GO:0006511 Not Cancer Driver No 112 0.114 530 62 0.117 0
USP38 USP38 Q8NB14 Ubiquitin carboxyl-terminal hydrolase 38 chr4 GO:0006511 Not Cancer Driver No 94 0.09 180 21 0.117 0
USP4 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 GO:0006511 Not Cancer Driver No 102 0.106 286 22 0.077 0
USP40_ENST00000427112 USP40 Q9NVE5 Ubiquitin carboxyl-terminal hydrolase 40 chr2 GO:0006511 Not Cancer Driver No 153 0.124 218 26 0.119 0
USP41 USP41 Q3LFD5 Putative ubiquitin carboxyl-terminal hydrolase 41 chr22 GO:0006511 Not Cancer Driver No 38 0.106 8 0 0.0 0
USP42 USP42 Q9H9J4 Ubiquitin carboxyl-terminal hydrolase 42 chr7 GO:0006511 Not Cancer Driver No 141 0.106 958 106 0.111 0
USP43 USP43 Q70EL4 Ubiquitin carboxyl-terminal hydrolase 43 chr17 GO:0006511 Not Cancer Driver No 134 0.119 562 56 0.1 0
USP45 USP45 Q70EL2 Ubiquitin carboxyl-terminal hydrolase 45 chr6 GO:0006511 Not Cancer Driver No 96 0.118 275 28 0.102 0
USP46 USP46 P62068 Ubiquitin carboxyl-terminal hydrolase 46 chr4 GO:0006511 Not Cancer Driver No 48 0.131 28 4 0.143 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0006511 Not Cancer Driver No 137 0.1 425 39 0.092 0
USP48 USP48 Q86UV5 Ubiquitin carboxyl-terminal hydrolase 48 chr1 GO:0006511 Not Cancer Driver No 125 0.121 178 21 0.118 0
USP49 USP49 Q70CQ1 Ubiquitin carboxyl-terminal hydrolase 49 chr6 GO:0006511 Not Cancer Driver No 81 0.118 190 19 0.1 0
USP5 USP5 P45974 Ubiquitin carboxyl-terminal hydrolase 5 chr12 GO:0006511 Not Cancer Driver No 117 0.136 262 38 0.145 0
USP50 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 GO:0006511 Not Cancer Driver No 33 0.097 2 0 0.0 0
USP51 USP51 Q70EK9 Ubiquitin carboxyl-terminal hydrolase 51 chrX GO:0006511 Not Cancer Driver No 100 0.141 246 34 0.138 0
USP6 USP6 P35125 Ubiquitin carboxyl-terminal hydrolase 6 chr17 GO:0006511 Census, Compendium Yes 243 0.173 537 83 0.155 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0006511 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0006511 Census, Compendium Yes 122 0.109 602 69 0.115 0
USP9Y USP9Y O00507 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y chrY GO:0006511 Not Cancer Driver No 83 0.032 349 6 0.017 0
WDR81 WDR81 Q562E7 WD repeat-containing protein 81 chr17 GO:0006511 Not Cancer Driver No 164 0.084 721 51 0.071 1
WDR91 WDR91 A4D1P6 WD repeat-containing protein 91 chr7 GO:0006511 Not Cancer Driver No 99 0.133 206 38 0.184 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0006511 Not Cancer Driver No 29 0.078 25 0 0.0 8
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0006511 Not Cancer Driver No 19 0.073 169 9 0.053 0
ZNRF3 ZNRF3 Q9ULT6 E3 ubiquitin-protein ligase ZNRF3 chr22 GO:0006511 Census, Compendium Yes 94 0.1 510 51 0.1 0
ZNRF4 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 GO:0006511 Not Cancer Driver No 115 0.268 99 26 0.263 0