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Total number of protein in "GO:0006508" GO term:  632

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACAN ACAN P16112 Aggrecan core protein chr15 GO:0006508 Not Cancer Driver No 477 0.189 1868 323 0.173 2
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0006508 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0006508 Not Cancer Driver No 104 0.129 68 5 0.074 0
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0006508 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM11 ADAM11 O75078 Disintegrin and metalloproteinase domain-containing protein 11 chr17 GO:0006508 Not Cancer Driver No 98 0.127 163 17 0.104 0
ADAM12 ADAM12 O43184 Disintegrin and metalloproteinase domain-containing protein 12 chr10 GO:0006508 Not Cancer Driver No 165 0.182 205 37 0.18 0
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0006508 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0006508 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM18 ADAM18 Q9Y3Q7 Disintegrin and metalloproteinase domain-containing protein 18 chr8 GO:0006508 Not Cancer Driver No 224 0.303 4 2 0.5 0
ADAM2 ADAM2 Q99965 Disintegrin and metalloproteinase domain-containing protein 2 chr8 GO:0006508 Not Cancer Driver No 194 0.264 18 4 0.222 0
ADAM21 ADAM21 Q9UKJ8 Disintegrin and metalloproteinase domain-containing protein 21 chr14 GO:0006508 Not Cancer Driver No 167 0.231 4 1 0.25 0
ADAM22 ADAM22 Q9P0K1 Disintegrin and metalloproteinase domain-containing protein 22 chr7 GO:0006508 Not Cancer Driver No 189 0.209 222 43 0.194 0
ADAM23 ADAM23 O75077 Disintegrin and metalloproteinase domain-containing protein 23 chr2 GO:0006508 Not Cancer Driver No 175 0.21 162 26 0.16 0
ADAM28 ADAM28 Q9UKQ2 Disintegrin and metalloproteinase domain-containing protein 28 chr8 GO:0006508 Not Cancer Driver No 193 0.249 123 24 0.195 0
ADAM29_ENST00000404450 ADAM29 Q9UKF5 Disintegrin and metalloproteinase domain-containing protein 29 chr4 GO:0006508 Not Cancer Driver No 257 0.313 124 39 0.315 0
ADAM30 ADAM30 Q9UKF2 Disintegrin and metalloproteinase domain-containing protein 30 chr1 GO:0006508 Not Cancer Driver No 133 0.168 73 12 0.164 0
ADAM32 ADAM32 Q8TC27 Disintegrin and metalloproteinase domain-containing protein 32 chr8 GO:0006508 Not Cancer Driver No 132 0.168 88 16 0.182 0
ADAM33 ADAM33 Q9BZ11 Disintegrin and metalloproteinase domain-containing protein 33 chr20 GO:0006508 Not Cancer Driver No 94 0.116 165 28 0.17 0
ADAM7 ADAM7 Q9H2U9 Disintegrin and metalloproteinase domain-containing protein 7 chr8 GO:0006508 Not Cancer Driver No 241 0.32 55 22 0.4 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0006508 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0006508 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADAMDEC1 ADAMDEC1 O15204 ADAM DEC1 chr8 GO:0006508 Not Cancer Driver No 117 0.249 106 30 0.283 0
ADAMTS1 ADAMTS1 Q9UHI8 A disintegrin and metalloproteinase with thrombospondin motifs 1 chr21 GO:0006508 Not Cancer Driver No 135 0.14 272 32 0.118 0
ADAMTS10_ENST00000597188 ADAMTS10 Q9H324 A disintegrin and metalloproteinase with thrombospondin motifs 10 chr19 GO:0006508 Not Cancer Driver No 193 0.175 157 35 0.223 1
ADAMTS13 ADAMTS13 Q76LX8 A disintegrin and metalloproteinase with thrombospondin motifs 13 chr9 GO:0006508 Not Cancer Driver No 172 0.121 285 35 0.123 43
ADAMTS14_ENST00000373207 ADAMTS14 Q8WXS8 A disintegrin and metalloproteinase with thrombospondin motifs 14 chr10 GO:0006508 Not Cancer Driver No 218 0.178 329 60 0.182 0
ADAMTS15 ADAMTS15 Q8TE58 A disintegrin and metalloproteinase with thrombospondin motifs 15 chr11 GO:0006508 Not Cancer Driver No 127 0.134 141 25 0.177 0
ADAMTS16 ADAMTS16 Q8TE57 A disintegrin and metalloproteinase with thrombospondin motifs 16 chr5 GO:0006508 Not Cancer Driver No 383 0.313 179 59 0.33 0
ADAMTS17 ADAMTS17 Q8TE56 A disintegrin and metalloproteinase with thrombospondin motifs 17 chr15 GO:0006508 Not Cancer Driver No 182 0.166 187 39 0.209 0
ADAMTS18 ADAMTS18 Q8TE60 A disintegrin and metalloproteinase with thrombospondin motifs 18 chr16 GO:0006508 Not Cancer Driver No 382 0.313 142 63 0.444 2
ADAMTS19 ADAMTS19 Q8TE59 A disintegrin and metalloproteinase with thrombospondin motifs 19 chr5 GO:0006508 Not Cancer Driver No 282 0.234 238 25 0.105 0
ADAMTS20 ADAMTS20 P59510 A disintegrin and metalloproteinase with thrombospondin motifs 20 chr12 GO:0006508 Not Cancer Driver No 495 0.259 120 33 0.275 0
ADAMTS4 ADAMTS4 O75173 A disintegrin and metalloproteinase with thrombospondin motifs 4 chr1 GO:0006508 Not Cancer Driver No 134 0.16 159 27 0.17 0
ADAMTS5 ADAMTS5 Q9UNA0 A disintegrin and metalloproteinase with thrombospondin motifs 5 chr21 GO:0006508 Not Cancer Driver No 227 0.244 148 33 0.223 0
ADAMTS6 ADAMTS6 Q9UKP5 A disintegrin and metalloproteinase with thrombospondin motifs 6 chr5 GO:0006508 Not Cancer Driver No 166 0.149 75 11 0.147 0
ADAMTS8 ADAMTS8 Q9UP79 A disintegrin and metalloproteinase with thrombospondin motifs 8 chr11 GO:0006508 Not Cancer Driver No 133 0.15 204 26 0.127 0
ADAMTS9 ADAMTS9 Q9P2N4 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 GO:0006508 Not Cancer Driver No 288 0.149 235 38 0.162 0
ADGB ADGB Q8N7X0 Androglobin chr6 GO:0006508 Not Cancer Driver No 141 0.085 706 68 0.096 0
ADGRG6_ENST00000230173 ADGRG6 Q86SQ4 Adhesion G-protein coupled receptor G6 chr6 GO:0006508 Not Cancer Driver No 132 0.108 23 0 0.0 2
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0006508 Not Cancer Driver No 1124 0.178 496 77 0.155 2
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 GO:0006508 Not Cancer Driver No 72 0.09 162 10 0.062 22
AGA AGA P20933 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase chr4 GO:0006508 Not Cancer Driver No 46 0.133 78 11 0.141 12
AGBL1_ENST00000441037 AGBL1 Q96MI9 Cytosolic carboxypeptidase 4 chr15 GO:0006508 Not Cancer Driver No 258 0.232 165 45 0.273 1
AGBL2 AGBL2 Q5U5Z8 Cytosolic carboxypeptidase 2 chr11 GO:0006508 Not Cancer Driver No 117 0.13 246 29 0.118 0
AGBL4 AGBL4 Q5VU57 Cytosolic carboxypeptidase 6 chr1 GO:0006508 Not Cancer Driver No 65 0.129 72 2 0.028 0
AGBL5 AGBL5 Q8NDL9 Cytosolic carboxypeptidase-like protein 5 chr2 GO:0006508 Not Cancer Driver No 127 0.143 487 74 0.152 2
AGTPBP1_ENST00000357081 AGTPBP1 Q9UPW5 Cytosolic carboxypeptidase 1 chr9 GO:0006508 Not Cancer Driver No 158 0.129 321 42 0.131 4
ALG13 ALG13 Q9NP73 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 chrX GO:0006508 Not Cancer Driver No 163 0.143 520 83 0.16 2
AMZ1 AMZ1 Q400G9 Archaemetzincin-1 chr7 GO:0006508 Not Cancer Driver No 78 0.157 147 18 0.122 0
AMZ2_ENST00000577866 AMZ2 Q86W34 Archaemetzincin-2 chr17 GO:0006508 Not Cancer Driver No 48 0.133 37 4 0.108 0
ANAPC1 ANAPC1 Q9H1A4 Anaphase-promoting complex subunit 1 chr2 GO:0006508 Not Cancer Driver No 206 0.106 263 33 0.125 0
ANAPC4_ENST00000315368 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 GO:0006508 Not Cancer Driver No 70 0.087 54 1 0.019 0
ANAPC5 ANAPC5 Q9UJX4 Anaphase-promoting complex subunit 5 chr12 GO:0006508 Not Cancer Driver No 94 0.125 41 4 0.098 0
ANPEP ANPEP P15144 Aminopeptidase N chr15 GO:0006508 Not Cancer Driver No 175 0.181 109 26 0.239 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0006508 Not Cancer Driver No 127 0.102 17 1 0.059 0
APEH APEH P13798 Acylamino-acid-releasing enzyme chr3 GO:0006508 Not Cancer Driver No 76 0.104 98 6 0.061 0
APH1A APH1A Q96BI3 Gamma-secretase subunit APH-1A chr1 GO:0006508 Not Cancer Driver No 32 0.121 0 0 0.0 0
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0006508 Not Cancer Driver No 67 0.194 0 0 0.0 0
ASCC2 ASCC2 Q9H1I8 Activating signal cointegrator 1 complex subunit 2 chr22 GO:0006508 Not Cancer Driver No 87 0.115 326 34 0.104 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 GO:0006508 Not Cancer Driver No 279 0.127 87 8 0.092 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0006508 Not Cancer Driver No 109 0.144 373 53 0.142 1
ASRGL1_ENST00000301776 ASRGL1 Q7L266 Isoaspartyl peptidase/L-asparaginase chr11 GO:0006508 Not Cancer Driver No 43 0.14 74 12 0.162 0
ASTL ASTL Q6HA08 Astacin-like metalloendopeptidase chr2 GO:0006508 Not Cancer Driver No 101 0.234 179 44 0.246 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 GO:0006508 Census, Compendium Yes 205 0.133 1300 174 0.134 0
ATG4A ATG4A Q8WYN0 Cysteine protease ATG4A chrX GO:0006508 Not Cancer Driver No 54 0.136 53 0 0.0 0
ATG4B ATG4B Q9Y4P1 Cysteine protease ATG4B chr2 GO:0006508 Not Cancer Driver No 34 0.087 13 2 0.154 0
ATG4C_ENST00000371120 ATG4C Q96DT6 Cysteine protease ATG4C chr1 GO:0006508 Not Cancer Driver No 62 0.135 17 3 0.176 0
ATG4D ATG4D Q86TL0 Cysteine protease ATG4D chr19 GO:0006508 Not Cancer Driver No 70 0.148 106 12 0.113 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX GO:0006508 Not Cancer Driver No 56 0.16 0 0 0.0 2
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0006508 Not Cancer Driver No 46 0.127 181 24 0.133 0
ATXN7L3_ENST00000389384 ATXN7L3 Q14CW9 Ataxin-7-like protein 3 chr17 GO:0006508 Not Cancer Driver No 41 0.118 241 27 0.112 0
ATXN7_ENST00000487717 ATXN7 O15265 Ataxin-7 chr3 GO:0006508 Not Cancer Driver No 95 0.107 797 82 0.103 0
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:0006508 Not Cancer Driver No 41 0.1 122 13 0.107 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0006508 Not Cancer Driver No 42 0.167 53 13 0.245 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0006508 Not Cancer Driver No 55 0.11 53 5 0.094 0
BACE2 BACE2 Q9Y5Z0 Beta-secretase 2 chr21 GO:0006508 Not Cancer Driver No 61 0.118 23 2 0.087 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0006508 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0006508 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0006508 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 GO:0006508 Census, Compendium Yes 141 0.193 418 59 0.141 0
BCHE BCHE P06276 Cholinesterase chr3 GO:0006508 Not Cancer Driver No 185 0.307 14 4 0.286 38
BLMH BLMH Q13867 Bleomycin hydrolase chr17 GO:0006508 Not Cancer Driver No 54 0.119 15 1 0.067 0
BMP1 BMP1 P13497 Bone morphogenetic protein 1 chr8 GO:0006508 Not Cancer Driver No 119 0.121 154 25 0.162 3
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX GO:0006508 Not Cancer Driver No 39 0.123 74 7 0.095 0
C1S C1S P09871 Complement C1s subcomponent chr12 GO:0006508 Not Cancer Driver No 128 0.186 97 21 0.216 1
C2 C2 P06681 Complement C2 chr6 GO:0006508 Not Cancer Driver No 120 0.16 120 17 0.142 3
C2orf40 ECRG4 Q9H1Z8 Augurin chr2 GO:0006508 Not Cancer Driver No 37 0.25 23 11 0.478 0
C9orf3 AOPEP Q8N6M6 Aminopeptidase O chr9 GO:0006508 Not Cancer Driver No 87 0.106 107 13 0.121 0
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0006508 Not Cancer Driver No 87 0.129 52 6 0.115 0
CAPN11 CAPN11 Q9UMQ6 Calpain-11 chr6 GO:0006508 Not Cancer Driver No 96 0.13 103 12 0.117 0
CAPN12 CAPN12 Q6ZSI9 Calpain-12 chr19 GO:0006508 Not Cancer Driver No 83 0.115 62 9 0.145 0
CAPN13 CAPN13 Q6MZZ7 Calpain-13 chr2 GO:0006508 Not Cancer Driver No 155 0.232 73 24 0.329 0
CAPN14 CAPN14 A8MX76 Calpain-14 chr2 GO:0006508 Not Cancer Driver No 47 0.069 22 2 0.091 0
CAPN15 CAPN15 O75808 Calpain-15 chr16 GO:0006508 Not Cancer Driver No 98 0.09 385 29 0.075 0
CAPN1_ENST00000533129 CAPN1 P07384 Calpain-1 catalytic subunit chr11 GO:0006508 Not Cancer Driver No 68 0.095 32 2 0.062 1
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0006508 Not Cancer Driver No 81 0.116 46 11 0.239 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0006508 Not Cancer Driver No 111 0.135 168 11 0.065 52
CAPN5 CAPN5 O15484 Calpain-5 chr11 GO:0006508 Not Cancer Driver No 103 0.161 110 25 0.227 2
CAPN6 CAPN6 Q9Y6Q1 Calpain-6 chrX GO:0006508 Not Cancer Driver No 156 0.243 19 8 0.421 0
CAPN7 CAPN7 Q9Y6W3 Calpain-7 chr3 GO:0006508 Not Cancer Driver No 80 0.098 92 9 0.098 0
CAPN8 CAPN8 A6NHC0 Calpain-8 chr1 GO:0006508 Not Cancer Driver No 36 0.051 76 6 0.079 0
CAPN9 CAPN9 O14815 Calpain-9 chr1 GO:0006508 Not Cancer Driver No 110 0.159 81 17 0.21 0
CAPNS2 CAPNS2 Q96L46 Calpain small subunit 2 chr16 GO:0006508 Not Cancer Driver No 21 0.085 56 5 0.089 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0006508 Not Cancer Driver No 53 0.099 126 7 0.056 1
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0006508 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP10_ENST00000272879 CASP10 Q92851 Caspase-10 chr2 GO:0006508 Not Cancer Driver No 57 0.109 126 17 0.135 3
CASP12 CASP12 Q6UXS9 Inactive caspase-12 chr11 GO:0006508 Not Cancer Driver No 12 0.035 31 1 0.032 0
CASP14 CASP14 P31944 Caspase-14 chr19 GO:0006508 Not Cancer Driver No 50 0.207 84 13 0.155 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0006508 Census Yes 32 0.116 62 5 0.081 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0006508 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASP5_ENST00000260315 CASP5 P51878 Caspase-5 chr11 GO:0006508 Not Cancer Driver No 103 0.237 61 17 0.279 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0006508 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 GO:0006508 Not Cancer Driver No 38 0.125 73 10 0.137 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0006508 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0006508 Census Yes 49 0.118 71 7 0.099 0
CDC16_ENST00000356221 CDC16 Q13042 Cell division cycle protein 16 homolog chr13 GO:0006508 Not Cancer Driver No 68 0.11 54 7 0.13 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0006508 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0006508 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDC23 CDC23 Q9UJX2 Cell division cycle protein 23 homolog chr5 GO:0006508 Not Cancer Driver No 57 0.095 45 6 0.133 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 GO:0006508 Not Cancer Driver No 179 0.217 289 75 0.26 0
CELA1 CELA1 Q9UNI1 Chymotrypsin-like elastase family member 1 chr12 GO:0006508 Not Cancer Driver No 48 0.186 20 0 0.0 0
CELA2A CELA2A P08217 Chymotrypsin-like elastase family member 2A chr1 GO:0006508 Not Cancer Driver No 39 0.145 4 4 1.0 2
CELA2B CELA2B P08218 Chymotrypsin-like elastase family member 2B chr1 GO:0006508 Not Cancer Driver No 40 0.149 3 0 0.0 0
CELA3A CELA3A P09093 Chymotrypsin-like elastase family member 3A chr1 GO:0006508 Not Cancer Driver No 48 0.178 12 2 0.167 0
CELA3B CELA3B P08861 Chymotrypsin-like elastase family member 3B chr1 GO:0006508 Not Cancer Driver No 55 0.204 20 7 0.35 0
CFAP44 CFAP44 Q96MT7 Cilia- and flagella-associated protein 44 chr3 GO:0006508 Not Cancer Driver No 187 0.101 614 49 0.08 0
CFB CFB P00751 Complement factor B chr6 GO:0006508 Not Cancer Driver No 75 0.098 112 20 0.179 7
CFD_ENST00000327726 CFD P00746 Complement factor D chr19 GO:0006508 Not Cancer Driver No 6 0.024 69 3 0.043 2
CFH CFH P08603 Complement factor H chr1 GO:0006508 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 GO:0006508 Not Cancer Driver No 97 0.166 4 0 0.0 13
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0006508 Not Cancer Driver No 40 0.083 44 2 0.045 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:0006508 Not Cancer Driver No 25 0.112 201 22 0.109 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 GO:0006508 Not Cancer Driver No 33 0.142 224 31 0.138 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0006508 Not Cancer Driver No 19 0.087 23 1 0.043 0
CLCA1 CLCA1 A8K7I4 Calcium-activated chloride channel regulator 1 chr1 GO:0006508 Not Cancer Driver No 144 0.158 212 22 0.104 0
CLCA2 CLCA2 Q9UQC9 Calcium-activated chloride channel regulator 2 chr1 GO:0006508 Not Cancer Driver No 131 0.139 222 35 0.158 0
CLCA4 CLCA4 Q14CN2 Calcium-activated chloride channel regulator 4 chr1 GO:0006508 Not Cancer Driver No 191 0.208 192 41 0.214 0
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 GO:0006508 Not Cancer Driver No 22 0.079 83 9 0.108 3
CLPX CLPX O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial chr15 GO:0006508 Not Cancer Driver No 66 0.104 195 22 0.113 1
CMA1 CMA1 P23946 Chymase chr14 GO:0006508 Not Cancer Driver No 47 0.19 9 1 0.111 0
CNDP1 CNDP1 Q96KN2 Beta-Ala-His dipeptidase chr18 GO:0006508 Not Cancer Driver No 104 0.205 26 3 0.115 0
CNDP2_ENST00000579847 CNDP2 Q96KP4 Cytosolic non-specific dipeptidase chr18 GO:0006508 Not Cancer Driver No 67 0.141 39 5 0.128 0
COLEC10 COLEC10 Q9Y6Z7 Collectin-10 chr8 GO:0006508 Not Cancer Driver No 58 0.209 95 23 0.242 1
COLEC11_ENST00000349077 COLEC11 Q9BWP8 Collectin-11 chr2 GO:0006508 Not Cancer Driver No 72 0.266 158 40 0.253 2
COPS2_ENST00000388901 COPS2 P61201 COP9 signalosome complex subunit 2 chr15 GO:0006508 Not Cancer Driver No 59 0.133 59 9 0.153 0
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 GO:0006508 Not Cancer Driver No 55 0.13 67 10 0.149 0
COPS4_ENST00000264389 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 GO:0006508 Not Cancer Driver No 50 0.123 13 0 0.0 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0006508 Not Cancer Driver No 36 0.108 32 7 0.219 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 GO:0006508 Not Cancer Driver No 38 0.116 30 6 0.2 0
COPS7A_ENST00000534947 COPS7A Q9UBW8 COP9 signalosome complex subunit 7a chr12 GO:0006508 Not Cancer Driver No 32 0.116 74 10 0.135 0
COPS7B_ENST00000410024 COPS7B Q9H9Q2 COP9 signalosome complex subunit 7b chr2 GO:0006508 Not Cancer Driver No 22 0.083 74 6 0.081 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0006508 Not Cancer Driver No 25 0.12 14 2 0.143 0
CORIN CORIN Q9Y5Q5 Atrial natriuretic peptide-converting enzyme chr4 GO:0006508 Not Cancer Driver No 208 0.2 60 13 0.217 2
CPA1 CPA1 P15085 Carboxypeptidase A1 chr7 GO:0006508 Not Cancer Driver No 84 0.2 5 1 0.2 0
CPA2 CPA2 P48052 Carboxypeptidase A2 chr7 GO:0006508 Not Cancer Driver No 62 0.148 26 2 0.077 0
CPA3 CPA3 P15088 Mast cell carboxypeptidase A chr3 GO:0006508 Not Cancer Driver No 111 0.266 38 9 0.237 0
CPA4 CPA4 Q9UI42 Carboxypeptidase A4 chr7 GO:0006508 Not Cancer Driver No 76 0.181 59 12 0.203 0
CPA5_ENST00000461828 CPA5 Q8WXQ8 Carboxypeptidase A5 chr7 GO:0006508 Not Cancer Driver No 79 0.181 40 4 0.1 0
CPA6 CPA6 Q8N4T0 Carboxypeptidase A6 chr8 GO:0006508 Not Cancer Driver No 106 0.243 7 0 0.0 2
CPB1_ENST00000282957 CPB1 P15086 Carboxypeptidase B chr3 GO:0006508 Not Cancer Driver No 91 0.218 15 2 0.133 0
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0006508 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPE CPE P16870 Carboxypeptidase E chr4 GO:0006508 Not Cancer Driver No 98 0.206 127 24 0.189 0
CPNE1_ENST00000352393 CPNE1 Q99829 Copine-1 chr20 GO:0006508 Not Cancer Driver No 74 0.138 80 7 0.087 0
CPO CPO Q8IVL8 Carboxypeptidase O chr2 GO:0006508 Not Cancer Driver No 62 0.166 16 2 0.125 0
CPQ CPQ Q9Y646 Carboxypeptidase Q chr8 GO:0006508 Not Cancer Driver No 110 0.233 3 0 0.0 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0006508 Not Cancer Driver No 368 0.245 73 22 0.301 140
CPVL_ENST00000265394 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 GO:0006508 Not Cancer Driver No 81 0.17 0 0 0.0 0
CPZ CPZ Q66K79 Carboxypeptidase Z chr4 GO:0006508 Not Cancer Driver No 163 0.25 71 31 0.437 0
CTRB1 CTRB1 P17538 Chymotrypsinogen B chr16 GO:0006508 Not Cancer Driver No 16 0.061 6 0 0.0 0
CTRB2 CTRB2 Q6GPI1 Chymotrypsinogen B2 chr16 GO:0006508 Not Cancer Driver No 14 0.053 6 0 0.0 0
CTRC CTRC Q99895 Chymotrypsin-C chr1 GO:0006508 Not Cancer Driver No 37 0.138 1 0 0.0 10
CTRL CTRL P40313 Chymotrypsin-like protease CTRL-1 chr16 GO:0006508 Not Cancer Driver No 32 0.121 0 0 0.0 0
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 GO:0006508 Not Cancer Driver No 59 0.123 14 1 0.071 12
CTSB CTSB P07858 Cathepsin B chr8 GO:0006508 Not Cancer Driver No 41 0.121 7 2 0.286 0
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:0006508 Not Cancer Driver No 64 0.138 19 5 0.263 29
CTSD CTSD P07339 Cathepsin D chr11 GO:0006508 Not Cancer Driver No 57 0.138 6 1 0.167 2
CTSE CTSE P14091 Cathepsin E chr1 GO:0006508 Not Cancer Driver No 59 0.149 23 2 0.087 0
CTSF CTSF Q9UBX1 Cathepsin F chr11 GO:0006508 Not Cancer Driver No 63 0.13 78 7 0.09 4
CTSG CTSG P08311 Cathepsin G chr14 GO:0006508 Not Cancer Driver No 65 0.255 80 29 0.362 0
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0006508 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSK CTSK P43235 Cathepsin K chr1 GO:0006508 Not Cancer Driver No 36 0.109 24 4 0.167 6
CTSL CTSL P07711 Procathepsin L chr9 GO:0006508 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSO CTSO P43234 Cathepsin O chr4 GO:0006508 Not Cancer Driver No 39 0.121 8 0 0.0 0
CTSS CTSS P25774 Cathepsin S chr1 GO:0006508 Not Cancer Driver No 54 0.163 0 0 0.0 0
CTSZ CTSZ Q9UBR2 Cathepsin Z chr20 GO:0006508 Not Cancer Driver No 30 0.099 10 0 0.0 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0006508 Census, Compendium Yes 123 0.16 167 23 0.138 3
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:0006508 Not Cancer Driver No 188 0.111 372 41 0.11 3
CUZD1_ENST00000392790 CUZD1 Q86UP6 CUB and zona pellucida-like domain-containing protein 1 chr10 GO:0006508 Not Cancer Driver No 82 0.135 24 6 0.25 0
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 GO:0006508 Not Cancer Driver No 12 0.114 19 3 0.158 1
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0006508 Not Cancer Driver No 211 0.165 86 11 0.128 3
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0006508 Census, Compendium Yes 116 0.121 213 31 0.146 3
DCAF12 DCAF12 Q5T6F0 DDB1- and CUL4-associated factor 12 chr9 GO:0006508 Not Cancer Driver No 59 0.13 70 7 0.1 0
DCD_ENST00000293371 DCD P81605 Dermcidin chr12 GO:0006508 Not Cancer Driver No 25 0.227 67 19 0.284 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0006508 Not Cancer Driver No 28 0.112 11 1 0.091 0
DESI1 DESI1 Q6ICB0 Desumoylating isopeptidase 1 chr22 GO:0006508 Not Cancer Driver No 23 0.137 34 6 0.176 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0006508 Not Cancer Driver No 55 0.107 0 0 0.0 6
DHH DHH O43323 Desert hedgehog protein chr12 GO:0006508 Not Cancer Driver No 36 0.091 57 7 0.123 1
DISP1 DISP1 Q96F81 Protein dispatched homolog 1 chr1 GO:0006508 Not Cancer Driver No 212 0.139 252 35 0.139 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 GO:0006508 Not Cancer Driver No 67 0.132 17 0 0.0 10
DNPEP_ENST00000273075 DNPEP Q9ULA0 Aspartyl aminopeptidase chr2 GO:0006508 Not Cancer Driver No 55 0.113 90 8 0.089 0
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0006508 Not Cancer Driver No 54 0.131 41 6 0.146 0
DPEP2_ENST00000393847 DPEP2 Q9H4A9 Dipeptidase 2 chr16 GO:0006508 Not Cancer Driver No 66 0.136 73 4 0.055 0
DPEP3 DPEP3 Q9H4B8 Dipeptidase 3 chr16 GO:0006508 Not Cancer Driver No 72 0.148 105 14 0.133 0
DPP10_ENST00000410059 DPP10 Q8N608 Inactive dipeptidyl peptidase 10 chr2 GO:0006508 Not Cancer Driver No 319 0.401 38 17 0.447 0
DPP3 DPP3 Q9NY33 Dipeptidyl peptidase 3 chr11 GO:0006508 Not Cancer Driver No 96 0.13 64 11 0.172 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0006508 Not Cancer Driver No 151 0.197 8 1 0.125 0
DPP6 DPP6 P42658 Dipeptidyl aminopeptidase-like protein 6 chr7 GO:0006508 Not Cancer Driver No 244 0.282 181 45 0.249 1
DPP7 DPP7 Q9UHL4 Dipeptidyl peptidase 2 chr9 GO:0006508 Not Cancer Driver No 41 0.083 29 0 0.0 0
DPP8_ENST00000559233 DPP8 Q6V1X1 Dipeptidyl peptidase 8 chr15 GO:0006508 Not Cancer Driver No 99 0.11 71 5 0.07 0
DPP9_ENST00000598800 DPP9 Q86TI2 Dipeptidyl peptidase 9 chr19 GO:0006508 Not Cancer Driver No 94 0.109 83 15 0.181 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 GO:0006508 Not Cancer Driver No 118 0.153 99 26 0.263 1
ECE2 ECE2 P0DPD6 Endothelin-converting enzyme 2 chr3 GO:0006508 Not Cancer Driver No 178 0.219 149 40 0.268 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 GO:0006508 Not Cancer Driver No 54 0.082 141 5 0.035 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 GO:0006508 Not Cancer Driver No 69 0.119 54 3 0.056 0
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 GO:0006508 Not Cancer Driver No 37 0.105 109 12 0.11 0
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0006508 Not Cancer Driver No 39 0.146 18 3 0.167 89
ENC1_ENST00000302351 ENC1 O14682 Ectoderm-neural cortex protein 1 chr5 GO:0006508 Not Cancer Driver No 85 0.144 8 0 0.0 0
ENDOU ENDOU P21128 Uridylate-specific endoribonuclease chr12 GO:0006508 Not Cancer Driver No 47 0.115 54 8 0.148 0
ENPEP ENPEP Q07075 Glutamyl aminopeptidase chr4 GO:0006508 Compendium Yes 235 0.246 130 44 0.338 0
ENY2 ENY2 Q9NPA8 Transcription and mRNA export factor ENY2 chr8 GO:0006508 Not Cancer Driver No 17 0.168 11 4 0.364 0
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 GO:0006508 Not Cancer Driver No 78 0.083 70 2 0.029 0
ERAP2 ERAP2 Q6P179 Endoplasmic reticulum aminopeptidase 2 chr5 GO:0006508 Not Cancer Driver No 97 0.101 23 4 0.174 0
ERMP1 ERMP1 Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 chr9 GO:0006508 Not Cancer Driver No 80 0.088 93 4 0.043 0
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0006508 Not Cancer Driver No 48 0.103 32 5 0.156 0
ESPL1 ESPL1 Q14674 Separin chr12 GO:0006508 Not Cancer Driver No 211 0.1 380 39 0.103 0
F10 F10 P00742 Coagulation factor X chr13 GO:0006508 Not Cancer Driver No 98 0.201 120 24 0.2 26
F11 F11 P03951 Coagulation factor XI chr4 GO:0006508 Not Cancer Driver No 108 0.173 1 0 0.0 58
F12 F12 P00748 Coagulation factor XII chr5 GO:0006508 Not Cancer Driver No 53 0.086 104 9 0.087 13
F2 F2 P00734 Prothrombin chr11 GO:0006508 Not Cancer Driver No 115 0.185 97 25 0.258 10
F3 F3 P13726 Tissue factor chr1 GO:0006508 Not Cancer Driver No 28 0.095 61 7 0.115 0
F9 F9 P00740 Coagulation factor IX chrX GO:0006508 Not Cancer Driver No 121 0.262 40 16 0.4 141
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0006508 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM111A FAM111A Q96PZ2 Serine protease FAM111A chr11 GO:0006508 Not Cancer Driver No 78 0.128 169 23 0.136 5
FAM111B_ENST00000620384 FAM111B Q6SJ93 Serine protease FAM111B chr11 GO:0006508 Not Cancer Driver No 92 0.125 190 18 0.095 3
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0006508 Not Cancer Driver No 158 0.208 6 2 0.333 0
FBXL2 FBXL2 Q9UKC9 F-box/LRR-repeat protein 2 chr3 GO:0006508 Not Cancer Driver No 48 0.113 0 0 0.0 0
FBXL6 FBXL6 Q8N531 F-box/LRR-repeat protein 6 chr8 GO:0006508 Not Cancer Driver No 48 0.089 114 5 0.044 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 GO:0006508 Not Cancer Driver No 21 0.071 75 1 0.013 0
FBXO3 FBXO3 Q9UK99 F-box only protein 3 chr11 GO:0006508 Not Cancer Driver No 56 0.119 51 7 0.137 0
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0006508 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 GO:0006508 Not Cancer Driver No 31 0.106 27 3 0.111 0
FBXW2 FBXW2 Q9UKT8 F-box/WD repeat-containing protein 2 chr9 GO:0006508 Not Cancer Driver No 49 0.108 0 0 0.0 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0006508 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:0006508 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0006508 Not Cancer Driver No 46 0.154 65 19 0.292 0
FEM1A FEM1A Q9BSK4 Protein fem-1 homolog A chr19 GO:0006508 Not Cancer Driver No 68 0.102 162 22 0.136 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0006508 Not Cancer Driver No 69 0.11 33 3 0.091 0
FEM1C FEM1C Q96JP0 Protein fem-1 homolog C chr5 GO:0006508 Not Cancer Driver No 55 0.089 27 1 0.037 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0006508 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0006508 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0006508 Not Cancer Driver No 81 0.179 53 8 0.151 8
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0006508 Not Cancer Driver No 71 0.162 70 12 0.171 0
FOLH1 FOLH1 Q04609 Glutamate carboxypeptidase 2 chr11 GO:0006508 Not Cancer Driver No 200 0.267 43 13 0.302 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0006508 Not Cancer Driver No 93 0.117 283 35 0.124 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0006508 Not Cancer Driver No 16 0.076 73 0 0.0 8
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0006508 Not Cancer Driver No 74 0.149 184 30 0.163 0
GGH GGH Q92820 Gamma-glutamyl hydrolase chr8 GO:0006508 Not Cancer Driver No 46 0.145 5 0 0.0 0
GGT1_ENST00000248923 GGT1 P19440 Glutathione hydrolase 1 proenzyme chr22 GO:0006508 Not Cancer Driver No 83 0.146 88 14 0.159 0
GGT5_ENST00000327365 GGT5 P36269 Glutathione hydrolase 5 proenzyme chr22 GO:0006508 Not Cancer Driver No 99 0.169 122 27 0.221 0
GGT6_ENST00000574154 GGT6 Q6P531 Glutathione hydrolase 6 chr17 GO:0006508 Not Cancer Driver No 51 0.103 211 32 0.152 0
GGT7 GGT7 Q9UJ14 Glutathione hydrolase 7 chr20 GO:0006508 Not Cancer Driver No 77 0.116 170 14 0.082 0
GGTLC1_ENST00000278765 GGTLC1 Q9BX51 Glutathione hydrolase light chain 1 chr20 GO:0006508 Not Cancer Driver No 63 0.28 81 17 0.21 0
GGTLC2 GGTLC2 Q14390 Glutathione hydrolase light chain 2 chr22 GO:0006508 Not Cancer Driver No 25 0.115 119 11 0.092 0
GPAA1 GPAA1 O43292 Glycosylphosphatidylinositol anchor attachment 1 protein chr8 GO:0006508 Not Cancer Driver No 55 0.089 20 3 0.15 5
GPS1_ENST00000306823 GPS1 Q13098 COP9 signalosome complex subunit 1 chr17 GO:0006508 Not Cancer Driver No 62 0.126 106 14 0.132 0
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0006508 Census, Compendium Yes 528 0.361 506 207 0.409 31
GZMH GZMH P20718 Granzyme H chr14 GO:0006508 Not Cancer Driver No 47 0.191 50 14 0.28 0
GZMK GZMK P49863 Granzyme K chr5 GO:0006508 Not Cancer Driver No 56 0.212 37 11 0.297 0
GZMM GZMM P51124 Granzyme M chr19 GO:0006508 Not Cancer Driver No 25 0.097 12 1 0.083 0
HABP2 HABP2 Q14520 Hyaluronan-binding protein 2 chr10 GO:0006508 Not Cancer Driver No 97 0.173 55 8 0.145 1
HGFAC_ENST00000382774 HGFAC Q04756 Hepatocyte growth factor activator chr4 GO:0006508 Not Cancer Driver No 96 0.147 112 15 0.134 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0006508 Compendium Yes 233 0.32 43 16 0.372 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:0006508 Not Cancer Driver No 11 0.087 6 0 0.0 6
HJV HJV Q6ZVN8 Hemojuvelin chr1 GO:0006508 Not Cancer Driver No 75 0.176 117 27 0.231 14
HM13_ENST00000340852 HM13 Q8TCT9 Minor histocompatibility antigen H13 chr20 GO:0006508 Not Cancer Driver No 42 0.111 61 6 0.098 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0006508 Not Cancer Driver No 37 0.105 131 16 0.122 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0006508 Not Cancer Driver No 60 0.144 12 0 0.0 0
HTRA1 HTRA1 Q92743 Serine protease HTRA1 chr10 GO:0006508 Not Cancer Driver No 77 0.16 40 9 0.225 11
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0006508 Compendium Yes 44 0.096 127 9 0.071 2
HTRA3 HTRA3 P83110 Serine protease HTRA3 chr4 GO:0006508 Not Cancer Driver No 64 0.141 57 11 0.193 0
HTRA4 HTRA4 P83105 Serine protease HTRA4 chr8 GO:0006508 Not Cancer Driver No 57 0.12 15 0 0.0 0
IDE IDE P14735 Insulin-degrading enzyme chr10 GO:0006508 Not Cancer Driver No 90 0.088 96 8 0.083 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0006508 Not Cancer Driver No 155 0.197 419 90 0.215 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0006508 Not Cancer Driver No 58 0.141 111 15 0.135 6
JMJD7 JMJD7 P0C870 Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 chr15 GO:0006508 Not Cancer Driver No 40 0.127 0 0 0.0 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0006508 Not Cancer Driver No 88 0.105 251 17 0.068 0
KDM8_ENST00000286096 KDM8 Q8N371 Bifunctional peptidase and arginyl-hydroxylase JMJD5 chr16 GO:0006508 Not Cancer Driver No 52 0.125 29 6 0.207 0
KLHDC1 KLHDC1 Q8N7A1 Kelch domain-containing protein 1 chr14 GO:0006508 Not Cancer Driver No 36 0.089 37 7 0.189 0
KLHDC10 KLHDC10 Q6PID8 Kelch domain-containing protein 10 chr7 GO:0006508 Not Cancer Driver No 40 0.09 93 3 0.032 0
KLHDC2 KLHDC2 Q9Y2U9 Kelch domain-containing protein 2 chr14 GO:0006508 Not Cancer Driver No 39 0.096 42 2 0.048 0
KLHDC3 KLHDC3 Q9BQ90 Kelch domain-containing protein 3 chr6 GO:0006508 Not Cancer Driver No 43 0.113 12 1 0.083 0
KLHL15 KLHL15 Q96M94 Kelch-like protein 15 chrX GO:0006508 Not Cancer Driver No 74 0.123 25 4 0.16 0
KLK10_ENST00000358789 KLK10 O43240 Kallikrein-10 chr19 GO:0006508 Not Cancer Driver No 35 0.127 30 8 0.267 0
KLK11 KLK11 Q9UBX7 Kallikrein-11 chr19 GO:0006508 Not Cancer Driver No 45 0.16 45 8 0.178 0
KLK12_ENST00000319590 KLK12 Q9UKR0 Kallikrein-12 chr19 GO:0006508 Not Cancer Driver No 38 0.153 0 0 0.0 0
KLK13 KLK13 Q9UKR3 Kallikrein-13 chr19 GO:0006508 Not Cancer Driver No 66 0.238 77 17 0.221 0
KLK14_ENST00000156499 KLK14 Q9P0G3 Kallikrein-14 chr19 GO:0006508 Not Cancer Driver No 41 0.154 29 6 0.207 0
KLK15 KLK15 Q9H2R5 Kallikrein-15 chr19 GO:0006508 Not Cancer Driver No 94 0.367 73 38 0.521 0
KLK3 KLK3 P07288 Prostate-specific antigen chr19 GO:0006508 Not Cancer Driver No 68 0.261 6 1 0.167 0
KLK4 KLK4 Q9Y5K2 Kallikrein-4 chr19 GO:0006508 Not Cancer Driver No 47 0.185 9 3 0.333 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 GO:0006508 Not Cancer Driver No 69 0.235 75 16 0.213 0
KLK6 KLK6 Q92876 Kallikrein-6 chr19 GO:0006508 Not Cancer Driver No 62 0.254 28 12 0.429 0
KLK7 KLK7 P49862 Kallikrein-7 chr19 GO:0006508 Not Cancer Driver No 43 0.17 38 8 0.211 0
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 GO:0006508 Not Cancer Driver No 65 0.25 76 15 0.197 0
KLK9 KLK9 Q9UKQ9 Kallikrein-9 chr19 GO:0006508 Not Cancer Driver No 34 0.136 2 0 0.0 0
KLKB1 KLKB1 P03952 Plasma kallikrein chr4 GO:0006508 Not Cancer Driver No 117 0.183 24 1 0.042 3
KY KY Q8NBH2 Kyphoscoliosis peptidase chr3 GO:0006508 Not Cancer Driver No 98 0.148 139 29 0.209 0
LACTB LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 GO:0006508 Not Cancer Driver No 44 0.08 121 3 0.025 0
LAP3 LAP3 P28838 Cytosol aminopeptidase chr4 GO:0006508 Not Cancer Driver No 59 0.114 99 14 0.141 0
LCN1 LCN1 P31025 Lipocalin-1 chr9 GO:0006508 Not Cancer Driver No 31 0.176 69 17 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0006508 Not Cancer Driver No 57 0.132 112 19 0.17 0
LMLN2 LMLN2 A0A1B0GTW7 Leishmanolysin-like peptidase 2 chr14 GO:0006508 Not Cancer Driver No 2 0.003 158 2 0.013 0
LMLN_ENST00000330198 LMLN Q96KR4 Leishmanolysin-like peptidase chr3 GO:0006508 Not Cancer Driver No 71 0.108 64 10 0.156 0
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 GO:0006508 Not Cancer Driver No 115 0.112 103 8 0.078 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0006508 Not Cancer Driver No 99 0.103 175 15 0.086 10
LPA LPA P08519 Apolipoprotein(a) chr6 GO:0006508 Not Cancer Driver No 365 0.179 884 148 0.167 0
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0006508 Not Cancer Driver No 94 0.098 190 24 0.126 0
LTA4H LTA4H P09960 Leukotriene A-4 hydrolase chr12 GO:0006508 Not Cancer Driver No 59 0.097 39 6 0.154 0
LTF LTF P02788 Lactotransferrin chr3 GO:0006508 Not Cancer Driver No 131 0.185 21 4 0.19 0
LTN1_ENST00000361371 LTN1 O94822 E3 ubiquitin-protein ligase listerin chr21 GO:0006508 Not Cancer Driver No 192 0.109 124 23 0.185 0
LVRN LVRN Q6Q4G3 Aminopeptidase Q chr5 GO:0006508 Not Cancer Driver No 212 0.214 81 20 0.247 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0006508 Census, Compendium Yes 75 0.091 139 12 0.086 1
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 GO:0006508 Not Cancer Driver No 142 0.203 72 14 0.194 0
MASP2 MASP2 O00187 Mannan-binding lectin serine protease 2 chr1 GO:0006508 Not Cancer Driver No 99 0.144 58 11 0.19 2
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0006508 Not Cancer Driver No 63 0.254 122 32 0.262 0
MBOAT4 MBOAT4 Q96T53 Ghrelin O-acyltransferase chr8 GO:0006508 Not Cancer Driver No 23 0.053 0 0 0.0 0
MBTPS1 MBTPS1 Q14703 Membrane-bound transcription factor site-1 protease chr16 GO:0006508 Not Cancer Driver No 140 0.133 206 36 0.175 1
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0006508 Not Cancer Driver No 63 0.121 16 4 0.25 9
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0006508 Census, Compendium Yes 56 0.114 297 37 0.125 0
MEP1A MEP1A Q16819 Meprin A subunit alpha chr6 GO:0006508 Not Cancer Driver No 163 0.218 140 20 0.143 0
MEP1B MEP1B Q16820 Meprin A subunit beta chr18 GO:0006508 Not Cancer Driver No 108 0.154 63 12 0.19 0
METAP1 METAP1 P53582 Methionine aminopeptidase 1 chr4 GO:0006508 Not Cancer Driver No 37 0.096 61 3 0.049 0
METAP1D METAP1D Q6UB28 Methionine aminopeptidase 1D, mitochondrial chr2 GO:0006508 Not Cancer Driver No 40 0.119 30 5 0.167 0
MIPEP MIPEP Q99797 Mitochondrial intermediate peptidase chr13 GO:0006508 Not Cancer Driver No 77 0.108 40 2 0.05 3
MMEL1 MMEL1 Q495T6 Membrane metallo-endopeptidase-like 1 chr1 GO:0006508 Not Cancer Driver No 117 0.15 46 5 0.109 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0006508 Not Cancer Driver No 189 0.252 40 17 0.425 4
MMP1 MMP1 P03956 Interstitial collagenase chr11 GO:0006508 Not Cancer Driver No 83 0.177 113 18 0.159 0
MMP10 MMP10 P09238 Stromelysin-2 chr11 GO:0006508 Not Cancer Driver No 88 0.185 38 9 0.237 0
MMP11 MMP11 P24347 Stromelysin-3 chr22 GO:0006508 Not Cancer Driver No 63 0.129 122 22 0.18 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0006508 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP13 MMP13 P45452 Collagenase 3 chr11 GO:0006508 Not Cancer Driver No 113 0.24 59 16 0.271 5
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0006508 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP15 MMP15 P51511 Matrix metalloproteinase-15 chr16 GO:0006508 Not Cancer Driver No 78 0.117 205 23 0.112 0
MMP16 MMP16 P51512 Matrix metalloproteinase-16 chr8 GO:0006508 Not Cancer Driver No 235 0.387 168 61 0.363 0
MMP17 MMP17 Q9ULZ9 Matrix metalloproteinase-17 chr12 GO:0006508 Not Cancer Driver No 93 0.154 241 26 0.108 0
MMP19 MMP19 Q99542 Matrix metalloproteinase-19 chr12 GO:0006508 Not Cancer Driver No 94 0.185 98 20 0.204 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0006508 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMP20 MMP20 O60882 Matrix metalloproteinase-20 chr11 GO:0006508 Not Cancer Driver No 79 0.164 69 8 0.116 0
MMP21 MMP21 Q8N119 Matrix metalloproteinase-21 chr10 GO:0006508 Not Cancer Driver No 75 0.132 147 11 0.075 8
MMP23B MMP23B O75900 Matrix metalloproteinase-23 chr1 GO:0006508 Not Cancer Driver No 3 0.008 35 0 0.0 0
MMP24 MMP24 Q9Y5R2 Matrix metalloproteinase-24 chr20 GO:0006508 Not Cancer Driver No 67 0.104 163 20 0.123 0
MMP25 MMP25 Q9NPA2 Matrix metalloproteinase-25 chr16 GO:0006508 Not Cancer Driver No 54 0.096 243 20 0.082 0
MMP26 MMP26 Q9NRE1 Matrix metalloproteinase-26 chr11 GO:0006508 Not Cancer Driver No 72 0.276 19 10 0.526 0
MMP27 MMP27 Q9H306 Matrix metalloproteinase-27 chr11 GO:0006508 Not Cancer Driver No 97 0.189 35 15 0.429 0
MMP3 MMP3 P08254 Stromelysin-1 chr11 GO:0006508 Not Cancer Driver No 99 0.208 66 14 0.212 0
MMP7 MMP7 P09237 Matrilysin chr11 GO:0006508 Not Cancer Driver No 39 0.146 70 2 0.029 0
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0006508 Not Cancer Driver No 73 0.156 115 19 0.165 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0006508 Not Cancer Driver No 129 0.182 124 26 0.21 0
MPND_ENST00000262966 MPND Q8N594 MPN domain-containing protein chr19 GO:0006508 Not Cancer Driver No 45 0.096 168 8 0.048 0
MST1 MST1 P26927 Hepatocyte growth factor-like protein chr3 GO:0006508 Not Cancer Driver No 110 0.155 168 19 0.113 0
MYRF MYRF Q9Y2G1 Myelin regulatory factor chr11 GO:0006508 Not Cancer Driver No 103 0.089 684 70 0.102 2
MYRFL MYRFL Q96LU7 Myelin regulatory factor-like protein chr12 GO:0006508 Not Cancer Driver No 8 0.009 316 2 0.006 0
MYSM1 MYSM1 Q5VVJ2 Deubiquitinase MYSM1 chr1 GO:0006508 Not Cancer Driver No 78 0.094 345 26 0.075 1
NAALAD2 NAALAD2 Q9Y3Q0 N-acetylated-alpha-linked acidic dipeptidase 2 chr11 GO:0006508 Not Cancer Driver No 165 0.223 22 4 0.182 0
NAALADL1 NAALADL1 Q9UQQ1 Aminopeptidase NAALADL1 chr11 GO:0006508 Not Cancer Driver No 105 0.142 135 17 0.126 0
NAALADL2 NAALADL2 Q58DX5 Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 chr3 GO:0006508 Not Cancer Driver No 162 0.204 207 46 0.222 0
NAPSA NAPSA O96009 Napsin-A chr19 GO:0006508 Not Cancer Driver No 58 0.138 14 1 0.071 0
NCLN NCLN Q969V3 Nicalin chr19 GO:0006508 Not Cancer Driver No 42 0.075 38 4 0.105 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0006508 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0006508 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 GO:0006508 Not Cancer Driver No 10 0.123 36 5 0.139 0
NEMF NEMF O60524 Ribosome quality control complex subunit NEMF chr14 GO:0006508 Not Cancer Driver No 109 0.101 517 61 0.118 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0006508 Census, Compendium Yes 228 0.377 402 62 0.154 4
NGLY1 NGLY1 Q96IV0 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase chr3 GO:0006508 Not Cancer Driver No 79 0.121 98 13 0.133 0
NLN NLN Q9BYT8 Neurolysin, mitochondrial chr5 GO:0006508 Not Cancer Driver No 70 0.099 25 3 0.12 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0006508 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0006508 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0006508 Not Cancer Driver No 106 0.119 203 28 0.138 0
NPEPL1 NPEPL1 Q8NDH3 Probable aminopeptidase NPEPL1 chr20 GO:0006508 Not Cancer Driver No 67 0.128 26 3 0.115 0
NPEPPS NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 GO:0006508 Compendium Yes 102 0.111 45 5 0.111 0
NRDC_ENST00000352171 NRDC O43847 Nardilysin chr1 GO:0006508 Not Cancer Driver No 162 0.141 253 34 0.134 0
NRIP2 NRIP2 Q9BQI9 Nuclear receptor-interacting protein 2 chr12 GO:0006508 Not Cancer Driver No 32 0.114 158 15 0.095 0
NRIP3 NRIP3 Q9NQ35 Nuclear receptor-interacting protein 3 chr11 GO:0006508 Not Cancer Driver No 34 0.141 111 16 0.144 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0006508 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 GO:0006508 Census Yes 227 0.125 1008 107 0.106 0
OLR1 OLR1 P78380 Oxidized low-density lipoprotein receptor 1 chr12 GO:0006508 Not Cancer Driver No 38 0.139 75 8 0.107 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 GO:0006508 Not Cancer Driver No 52 0.099 34 4 0.118 0
OTUB2 OTUB2 Q96DC9 Ubiquitin thioesterase OTUB2 chr14 GO:0006508 Not Cancer Driver No 30 0.128 0 0 0.0 0
OTUD3 OTUD3 Q5T2D3 OTU domain-containing protein 3 chr1 GO:0006508 Not Cancer Driver No 43 0.108 280 25 0.089 0
OTUD6A OTUD6A Q7L8S5 OTU domain-containing protein 6A chrX GO:0006508 Not Cancer Driver No 71 0.247 126 25 0.198 0
OTUD7A OTUD7A Q8TE49 OTU domain-containing protein 7A chr15 GO:0006508 Not Cancer Driver No 121 0.131 591 65 0.11 0
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 GO:0006508 Not Cancer Driver No 124 0.147 537 87 0.162 0
OTULIN OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 GO:0006508 Not Cancer Driver No 47 0.134 97 5 0.052 2
OVCH1 OVCH1 Q7RTY7 Ovochymase-1 chr12 GO:0006508 Not Cancer Driver No 216 0.19 88 13 0.148 0
OVCH2_ENST00000612000 OVCH2 Q7RTZ1 Ovochymase-2 chr11 GO:0006508 Not Cancer Driver No 75 0.133 4 0 0.0 0
PAPLN_ENST00000644200 PAPLN O95428 Papilin chr14 GO:0006508 Not Cancer Driver No 175 0.137 572 74 0.129 0
PAPPA PAPPA Q13219 Pappalysin-1 chr9 GO:0006508 Not Cancer Driver No 370 0.227 239 37 0.155 0
PAPPA2 PAPPA2 Q9BXP8 Pappalysin-2 chr1 GO:0006508 Not Cancer Driver No 739 0.413 370 141 0.381 1
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0006508 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 GO:0006508 Not Cancer Driver No 49 0.129 28 5 0.179 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0006508 Not Cancer Driver No 119 0.117 320 34 0.106 0
PCOLCE PCOLCE Q15113 Procollagen C-endopeptidase enhancer 1 chr7 GO:0006508 Not Cancer Driver No 46 0.102 187 18 0.096 0
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0006508 Not Cancer Driver No 139 0.185 336 61 0.182 2
PCSK1N PCSK1N Q9UHG2 ProSAAS chrX GO:0006508 Not Cancer Driver No 7 0.027 187 7 0.037 0
PCSK2 PCSK2 P16519 Neuroendocrine convertase 2 chr20 GO:0006508 Not Cancer Driver No 144 0.226 153 39 0.255 0
PCSK4 PCSK4 Q6UW60 Proprotein convertase subtilisin/kexin type 4 chr19 GO:0006508 Not Cancer Driver No 83 0.11 149 20 0.134 0
PCSK5 PCSK5 Q92824 Proprotein convertase subtilisin/kexin type 5 chr9 GO:0006508 Not Cancer Driver No 319 0.172 168 25 0.149 0
PCSK6 PCSK6 P29122 Proprotein convertase subtilisin/kexin type 6 chr15 GO:0006508 Not Cancer Driver No 138 0.142 207 45 0.217 0
PCSK7 PCSK7 Q16549 Proprotein convertase subtilisin/kexin type 7 chr11 GO:0006508 Not Cancer Driver No 101 0.129 262 31 0.118 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0006508 Not Cancer Driver No 86 0.124 148 27 0.182 9
PCYOX1 PCYOX1 Q9UHG3 Prenylcysteine oxidase 1 chr2 GO:0006508 Not Cancer Driver No 60 0.119 9 1 0.111 0
PCYOX1L PCYOX1L Q8NBM8 Prenylcysteine oxidase-like chr5 GO:0006508 Not Cancer Driver No 61 0.123 0 0 0.0 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 GO:0006508 Not Cancer Driver No 85 0.098 272 22 0.081 0
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 GO:0006508 Not Cancer Driver No 57 0.113 98 11 0.112 0
PEPD PEPD P12955 Xaa-Pro dipeptidase chr19 GO:0006508 Not Cancer Driver No 53 0.108 17 2 0.118 4
PERP PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0006508 Not Cancer Driver No 28 0.145 0 0 0.0 1
PGA3 PGA3 P0DJD8 Pepsin A-3 chr11 GO:0006508 Not Cancer Driver No 19 0.049 24 1 0.042 0
PGA4 PGA4 P0DJD7 Pepsin A-4 chr11 GO:0006508 Not Cancer Driver No 0 0.0 24 0 0.0 0
PGA5 PGA5 P0DJD9 Pepsin A-5 chr11 GO:0006508 Not Cancer Driver No 25 0.064 24 2 0.083 0
PGC PGC P20142 Gastricsin chr6 GO:0006508 Not Cancer Driver No 60 0.155 20 1 0.05 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX GO:0006508 Not Cancer Driver No 61 0.146 40 5 0.125 9
PGPEP1 PGPEP1 Q9NXJ5 Pyroglutamyl-peptidase 1 chr19 GO:0006508 Not Cancer Driver No 22 0.105 0 0 0.0 0
PGPEP1L PGPEP1L A6NFU8 Pyroglutamyl-peptidase 1-like protein chr15 GO:0006508 Not Cancer Driver No 36 0.184 20 2 0.1 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0006508 Not Cancer Driver No 144 0.192 56 7 0.125 30
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 GO:0006508 Not Cancer Driver No 93 0.102 137 14 0.102 0
PIGK PIGK Q92643 GPI-anchor transamidase chr1 GO:0006508 Not Cancer Driver No 54 0.137 37 9 0.243 5
PIP PIP P12273 Prolactin-inducible protein chr7 GO:0006508 Not Cancer Driver No 42 0.288 0 0 0.0 0
PISD_ENST00000439502 PISD Q9UG56 Phosphatidylserine decarboxylase proenzyme, mitochondrial chr22 GO:0006508 Not Cancer Driver No 42 0.103 8 3 0.375 2
PITRM1_ENST00000224949 PITRM1 Q5JRX3 Presequence protease, mitochondrial chr10 GO:0006508 Not Cancer Driver No 122 0.118 220 26 0.118 2
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0006508 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0006508 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLAU PLAU P00749 Urokinase-type plasminogen activator chr10 GO:0006508 Not Cancer Driver No 59 0.137 10 0 0.0 0
PLG PLG P00747 Plasminogen chr6 GO:0006508 Not Cancer Driver No 242 0.299 230 64 0.278 9
PM20D1 PM20D1 Q6GTS8 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 chr1 GO:0006508 Not Cancer Driver No 79 0.157 42 10 0.238 0
PM20D2 PM20D2 Q8IYS1 Xaa-Arg dipeptidase chr6 GO:0006508 Not Cancer Driver No 39 0.089 79 7 0.089 0
PRCP_ENST00000313010 PRCP P42785 Lysosomal Pro-X carboxypeptidase chr11 GO:0006508 Not Cancer Driver No 58 0.117 0 0 0.0 0
PREP PREP P48147 Prolyl endopeptidase chr6 GO:0006508 Not Cancer Driver No 87 0.123 23 1 0.043 0
PREPL_ENST00000409272 PREPL Q4J6C6 Prolyl endopeptidase-like chr2 GO:0006508 Not Cancer Driver No 107 0.147 91 20 0.22 0
PROC PROC P04070 Vitamin K-dependent protein C chr2 GO:0006508 Not Cancer Driver No 73 0.158 41 9 0.22 36
PROZ_ENST00000375547 PROZ P22891 Vitamin K-dependent protein Z chr13 GO:0006508 Not Cancer Driver No 41 0.102 13 3 0.231 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 GO:0006508 Not Cancer Driver No 255 0.109 225 26 0.116 8
PRSS1 PRSS1 P07477 Serine protease 1 chr7 GO:0006508 Not Cancer Driver No 121 0.49 0 0 0.0 12
PRSS16 PRSS16 Q9NQE7 Thymus-specific serine protease chr6 GO:0006508 Not Cancer Driver No 85 0.165 26 5 0.192 0
PRSS21 PRSS21 Q9Y6M0 Testisin chr16 GO:0006508 Not Cancer Driver No 41 0.131 6 0 0.0 0
PRSS22 PRSS22 Q9GZN4 Brain-specific serine protease 4 chr16 GO:0006508 Not Cancer Driver No 37 0.117 28 5 0.179 0
PRSS23 PRSS23 O95084 Serine protease 23 chr11 GO:0006508 Not Cancer Driver No 53 0.138 51 4 0.078 0
PRSS27 PRSS27 Q9BQR3 Serine protease 27 chr16 GO:0006508 Not Cancer Driver No 18 0.062 21 1 0.048 0
PRSS2_ENST00000539842 PRSS2 P07478 Trypsin-2 chr7 GO:0006508 Not Cancer Driver No 51 0.206 9 1 0.111 0
PRSS3 PRSS3 P35030 Trypsin-3 chr9 GO:0006508 Not Cancer Driver No 50 0.164 30 0 0.0 0
PRSS33 PRSS33 Q8NF86 Serine protease 33 chr16 GO:0006508 Not Cancer Driver No 17 0.061 73 1 0.014 0
PRSS36 PRSS36 Q5K4E3 Polyserase-2 chr16 GO:0006508 Not Cancer Driver No 84 0.098 176 26 0.148 0
PRSS37_ENST00000438520 PRSS37 A4D1T9 Probable inactive serine protease 37 chr7 GO:0006508 Not Cancer Driver No 47 0.2 29 8 0.276 0
PRSS38 PRSS38 A1L453 Serine protease 38 chr1 GO:0006508 Not Cancer Driver No 73 0.224 3 1 0.333 0
PRSS41 PRSS41 Q7RTY9 Serine protease 41 chr16 GO:0006508 Not Cancer Driver No 23 0.072 23 2 0.087 0
PRSS42 PRSS42P Q7Z5A4 Putative serine protease 42 chr3 GO:0006508 Not Cancer Driver No 37 0.126 42 1 0.024 0
PRSS45_ENST00000620911 PRSS45P Q7RTY3 Putative serine protease 45 chr3 GO:0006508 Not Cancer Driver No 35 0.135 0 0 0.0 0
PRSS48 PRSS48 Q7RTY5 Serine protease 48 chr4 GO:0006508 Not Cancer Driver No 63 0.192 2 0 0.0 0
PRSS50 PRSS50 Q9UI38 Probable threonine protease PRSS50 chr3 GO:0006508 Not Cancer Driver No 104 0.27 63 26 0.413 0
PRSS51_ENST00000636217 PRSS51 A0A1B0GVH4 Serine protease-like protein 51 chr8 GO:0006508 Not Cancer Driver No 3 0.014 29 0 0.0 0
PRSS53 PRSS53 Q2L4Q9 Serine protease 53 chr16 GO:0006508 Not Cancer Driver No 48 0.087 148 10 0.068 0
PRSS54 PRSS54 Q6PEW0 Inactive serine protease 54 chr16 GO:0006508 Not Cancer Driver No 62 0.157 56 10 0.179 0
PRSS55 PRSS55 Q6UWB4 Serine protease 55 chr8 GO:0006508 Not Cancer Driver No 77 0.219 64 16 0.25 0
PRSS57 PRSS57 Q6UWY2 Serine protease 57 chr19 GO:0006508 Not Cancer Driver No 39 0.138 50 5 0.1 0
PRSS58_ENST00000547058 PRSS58 Q8IYP2 Serine protease 58 chr7 GO:0006508 Not Cancer Driver No 81 0.336 0 0 0.0 0
PRSS8 PRSS8 Q16651 Prostasin chr16 GO:0006508 Not Cancer Driver No 30 0.087 27 3 0.111 0
PRTN3 PRTN3 P24158 Myeloblastin chr19 GO:0006508 Not Cancer Driver No 20 0.078 46 1 0.022 0
PSENEN_ENST00000222266 PSENEN Q9NZ42 Gamma-secretase subunit PEN-2 chr19 GO:0006508 Not Cancer Driver No 17 0.168 0 0 0.0 0
PSMB11 PSMB11 A5LHX3 Proteasome subunit beta type-11 chr14 GO:0006508 Not Cancer Driver No 62 0.207 71 11 0.155 0
PSMB5 PSMB5 P28074 Proteasome subunit beta type-5 chr14 GO:0006508 Not Cancer Driver No 39 0.148 9 0 0.0 0
PSMC4 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 GO:0006508 Not Cancer Driver No 51 0.122 21 3 0.143 0
PSME4 PSME4 Q14997 Proteasome activator complex subunit 4 chr2 GO:0006508 Not Cancer Driver No 214 0.116 134 12 0.09 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0006508 Not Cancer Driver No 16 0.082 39 4 0.103 0
PYDC1 PYDC1 Q8WXC3 Pyrin domain-containing protein 1 chr16 GO:0006508 Not Cancer Driver No 28 0.315 0 0 0.0 0
QPCT QPCT Q16769 Glutaminyl-peptide cyclotransferase chr2 GO:0006508 Not Cancer Driver No 44 0.122 41 3 0.073 0
QPCTL QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 GO:0006508 Not Cancer Driver No 42 0.11 22 1 0.045 0
RCE1 RCE1 Q9Y256 CAAX prenyl protease 2 chr11 GO:0006508 Not Cancer Driver No 40 0.122 0 0 0.0 0
RELN RELN P78509 Reelin chr7 GO:0006508 Not Cancer Driver No 761 0.22 107 19 0.178 7
REN REN P00797 Renin chr1 GO:0006508 Not Cancer Driver No 60 0.148 10 0 0.0 3
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 GO:0006508 Not Cancer Driver No 38 0.121 69 9 0.13 0
RHBDD3 RHBDD3 Q9Y3P4 Rhomboid domain-containing protein 3 chr22 GO:0006508 Not Cancer Driver No 24 0.062 147 16 0.109 0
RHBDL1_ENST00000219551 RHBDL1 O75783 Rhomboid-related protein 1 chr16 GO:0006508 Not Cancer Driver No 36 0.082 115 3 0.026 0
RHBDL2_ENST00000372990 RHBDL2 Q9NX52 Rhomboid-related protein 2 chr1 GO:0006508 Not Cancer Driver No 48 0.158 29 10 0.345 0
RHBDL3 RHBDL3 P58872 Rhomboid-related protein 3 chr17 GO:0006508 Not Cancer Driver No 52 0.129 49 2 0.041 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0006508 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0006508 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF126 RNF126 Q9BV68 E3 ubiquitin-protein ligase RNF126 chr19 GO:0006508 Not Cancer Driver No 33 0.106 182 22 0.121 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0006508 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0006508 Not Cancer Driver No 17 0.094 69 3 0.043 0
RNPEP RNPEP Q9H4A4 Aminopeptidase B chr1 GO:0006508 Not Cancer Driver No 60 0.092 86 4 0.047 0
RNPEPL1 RNPEPL1 Q9HAU8 Aminopeptidase RNPEPL1 chr2 GO:0006508 Not Cancer Driver No 55 0.076 82 2 0.024 0
SCG5 SCG5 P05408 Neuroendocrine protein 7B2 chr15 GO:0006508 Not Cancer Driver No 25 0.118 174 21 0.121 0
SCPEP1 SCPEP1 Q9HB40 Retinoid-inducible serine carboxypeptidase chr17 GO:0006508 Not Cancer Driver No 46 0.102 1 0 0.0 0
SCRN1_ENST00000242059 SCRN1 Q12765 Secernin-1 chr7 GO:0006508 Not Cancer Driver No 73 0.176 112 21 0.188 0
SCRN2 SCRN2 Q96FV2 Secernin-2 chr17 GO:0006508 Not Cancer Driver No 65 0.153 145 24 0.166 0
SCRN3 SCRN3 Q0VDG4 Secernin-3 chr2 GO:0006508 Not Cancer Driver No 55 0.13 42 3 0.071 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 GO:0006508 Not Cancer Driver No 16 0.072 130 9 0.069 0
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 GO:0006508 Not Cancer Driver No 64 0.099 355 44 0.124 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0006508 Not Cancer Driver No 73 0.124 285 38 0.133 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 GO:0006508 Not Cancer Driver No 53 0.092 288 30 0.104 0
SENP5 SENP5 Q96HI0 Sentrin-specific protease 5 chr3 GO:0006508 Not Cancer Driver No 85 0.113 293 34 0.116 0
SENP6 SENP6 Q9GZR1 Sentrin-specific protease 6 chr6 GO:0006508 Not Cancer Driver No 120 0.108 612 59 0.096 0
SENP7 SENP7 Q9BQF6 Sentrin-specific protease 7 chr3 GO:0006508 Not Cancer Driver No 149 0.142 523 73 0.14 0
SF3B3 SF3B3 Q15393 Splicing factor 3B subunit 3 chr16 GO:0006508 Not Cancer Driver No 154 0.127 145 19 0.131 0
SF3B5 SF3B5 Q9BWJ5 Splicing factor 3B subunit 5 chr6 GO:0006508 Not Cancer Driver No 8 0.093 16 2 0.125 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0006508 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 GO:0006508 Not Cancer Driver No 31 0.106 131 17 0.13 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0006508 Not Cancer Driver No 56 0.121 139 14 0.101 81
SLC30A5 SLC30A5 Q8TAD4 Zinc transporter 5 chr5 GO:0006508 Not Cancer Driver No 58 0.076 33 0 0.0 0
SLC30A6_ENST00000282587 SLC30A6 Q6NXT4 Zinc transporter 6 chr2 GO:0006508 Not Cancer Driver No 54 0.117 93 7 0.075 0
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 GO:0006508 Not Cancer Driver No 115 0.312 25 9 0.36 0
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 GO:0006508 Not Cancer Driver No 89 0.118 256 31 0.121 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0006508 Not Cancer Driver No 87 0.116 242 28 0.116 0
SPATA2_ENST00000289431 SPATA2 Q9UM82 Spermatogenesis-associated protein 2 chr20 GO:0006508 Not Cancer Driver No 70 0.135 235 39 0.166 0
SPCS1 SPCS1 Q9Y6A9 Signal peptidase complex subunit 1 chr3 GO:0006508 Not Cancer Driver No 18 0.107 81 9 0.111 0
SPCS3 SPCS3 P61009 Signal peptidase complex subunit 3 chr4 GO:0006508 Not Cancer Driver No 25 0.139 0 0 0.0 0
SPG7 SPG7 Q9UQ90 Paraplegin chr16 GO:0006508 Not Cancer Driver No 97 0.122 181 29 0.16 4
SPPL2A SPPL2A Q8TCT8 Signal peptide peptidase-like 2A chr15 GO:0006508 Not Cancer Driver No 55 0.106 3 0 0.0 0
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 GO:0006508 Not Cancer Driver No 68 0.115 99 17 0.172 0
SPPL2C SPPL2C Q8IUH8 Signal peptide peptidase-like 2C chr17 GO:0006508 Not Cancer Driver No 110 0.161 216 45 0.208 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0006508 Not Cancer Driver No 73 0.149 252 38 0.151 1
ST14 ST14 Q9Y5Y6 Suppressor of tumorigenicity 14 protein chr11 GO:0006508 Not Cancer Driver No 106 0.124 47 5 0.106 1
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0006508 Not Cancer Driver No 35 0.116 112 14 0.125 12
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0006508 Census Yes 55 0.114 199 19 0.095 2
SUPT20H_ENST00000350612 SUPT20H Q8NEM7 Transcription factor SPT20 homolog chr13 GO:0006508 Not Cancer Driver No 93 0.119 426 56 0.131 0
SUPT3H_ENST00000371459 SUPT3H O75486 Transcription initiation protein SPT3 homolog chr6 GO:0006508 Not Cancer Driver No 49 0.155 49 4 0.082 0
SUPT7L SUPT7L O94864 STAGA complex 65 subunit gamma chr2 GO:0006508 Not Cancer Driver No 41 0.099 281 30 0.107 0
SVBP_ENST00000372522 SVBP Q8N300 Small vasohibin-binding protein chr1 GO:0006508 Not Cancer Driver No 7 0.106 66 7 0.106 0
TADA1 TADA1 Q96BN2 Transcriptional adapter 1 chr1 GO:0006508 Not Cancer Driver No 38 0.113 116 12 0.103 0
TADA2B TADA2B Q86TJ2 Transcriptional adapter 2-beta chr4 GO:0006508 Not Cancer Driver No 55 0.131 128 19 0.148 0
TADA3 TADA3 O75528 Transcriptional adapter 3 chr3 GO:0006508 Not Cancer Driver No 54 0.125 353 43 0.122 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:0006508 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAF12_ENST00000373824 TAF12 Q16514 Transcription initiation factor TFIID subunit 12 chr1 GO:0006508 Not Cancer Driver No 11 0.068 107 7 0.065 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0006508 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 GO:0006508 Not Cancer Driver No 129 0.108 241 34 0.141 1
TAF4 TAF4 O00268 Transcription initiation factor TFIID subunit 4 chr20 GO:0006508 Not Cancer Driver No 112 0.103 975 96 0.098 0
TAF5 TAF5 Q15542 Transcription initiation factor TFIID subunit 5 chr10 GO:0006508 Not Cancer Driver No 61 0.076 294 12 0.041 0
TAF5L TAF5L O75529 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L chr1 GO:0006508 Not Cancer Driver No 87 0.148 69 11 0.159 0
TAF6L TAF6L Q9Y6J9 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L chr11 GO:0006508 Not Cancer Driver No 64 0.103 246 20 0.081 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 GO:0006508 Not Cancer Driver No 79 0.117 288 32 0.111 2
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 GO:0006508 Not Cancer Driver No 40 0.115 258 31 0.12 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0006508 Not Cancer Driver No 25 0.095 203 19 0.094 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0006508 Not Cancer Driver No 42 0.099 302 26 0.086 0
TASP1 TASP1 Q9H6P5 Threonine aspartase 1 chr20 GO:0006508 Not Cancer Driver No 59 0.14 81 11 0.136 1
TBC1D10A_ENST00000215790 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0006508 Not Cancer Driver No 72 0.142 209 26 0.124 0
TBL1X TBL1X O60907 F-box-like/WD repeat-containing protein TBL1X chrX GO:0006508 Not Cancer Driver No 85 0.147 181 35 0.193 0
TFR2_ENST00000223051 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 GO:0006508 Not Cancer Driver No 94 0.117 168 20 0.119 3
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0006508 Census Yes 89 0.117 80 6 0.075 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0006508 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0006508 Not Cancer Driver No 61 0.132 219 34 0.155 0
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0006508 Not Cancer Driver No 123 0.179 107 26 0.243 0
THOP1 THOP1 P52888 Thimet oligopeptidase chr19 GO:0006508 Not Cancer Driver No 90 0.131 91 12 0.132 0
TINAG TINAG Q9UJW2 Tubulointerstitial nephritis antigen chr6 GO:0006508 Not Cancer Driver No 141 0.296 62 22 0.355 0
TINAGL1 TINAGL1 Q9GZM7 Tubulointerstitial nephritis antigen-like chr1 GO:0006508 Not Cancer Driver No 62 0.133 89 15 0.169 0
TLL1 TLL1 O43897 Tolloid-like protein 1 chr4 GO:0006508 Compendium Yes 333 0.329 138 57 0.413 3
TLL2 TLL2 Q9Y6L7 Tolloid-like protein 2 chr10 GO:0006508 Not Cancer Driver No 174 0.171 176 33 0.188 0
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 GO:0006508 Not Cancer Driver No 39 0.121 26 3 0.115 0
TMPRSS11A_ENST00000508048 TMPRSS11A Q6ZMR5 Transmembrane protease serine 11A chr4 GO:0006508 Not Cancer Driver No 91 0.218 3 1 0.333 0
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 GO:0006508 Not Cancer Driver No 95 0.228 5 0 0.0 0
TMPRSS11D TMPRSS11D O60235 Transmembrane protease serine 11D chr4 GO:0006508 Not Cancer Driver No 86 0.206 26 4 0.154 0
TMPRSS11E TMPRSS11E Q9UL52 Transmembrane protease serine 11E chr4 GO:0006508 Not Cancer Driver No 105 0.248 35 9 0.257 0
TMPRSS11F TMPRSS11F Q6ZWK6 Transmembrane protease serine 11F chr4 GO:0006508 Not Cancer Driver No 119 0.272 29 13 0.448 0
TMPRSS13_ENST00000445164 TMPRSS13 Q9BYE2 Transmembrane protease serine 13 chr11 GO:0006508 Not Cancer Driver No 122 0.208 199 75 0.377 0
TMPRSS15 TMPRSS15 P98073 Enteropeptidase chr21 GO:0006508 Not Cancer Driver No 278 0.273 51 14 0.275 0
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 GO:0006508 Census Yes 66 0.134 25 5 0.2 0
TMPRSS3_ENST00000433957 TMPRSS3 P57727 Transmembrane protease serine 3 chr21 GO:0006508 Not Cancer Driver No 78 0.172 8 3 0.375 8
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 GO:0006508 Not Cancer Driver No 47 0.108 35 4 0.114 0
TMPRSS5 TMPRSS5 Q9H3S3 Transmembrane protease serine 5 chr11 GO:0006508 Not Cancer Driver No 46 0.101 33 1 0.03 0
TMPRSS6_ENST00000346753 TMPRSS6 Q8IU80 Transmembrane protease serine 6 chr22 GO:0006508 Not Cancer Driver No 125 0.154 36 7 0.194 25
TMPRSS7_ENST00000452346 TMPRSS7 Q7RTY8 Transmembrane protease serine 7 chr3 GO:0006508 Not Cancer Driver No 112 0.133 41 2 0.049 0
TMPRSS9 TMPRSS9 Q7Z410 Transmembrane protease serine 9 chr19 GO:0006508 Not Cancer Driver No 127 0.12 188 22 0.117 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0006508 Census, Compendium Yes 98 0.124 231 33 0.143 1
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0006508 Not Cancer Driver No 33 0.099 0 0 0.0 3
TPP1 TPP1 O14773 Tripeptidyl-peptidase 1 chr11 GO:0006508 Not Cancer Driver No 67 0.119 92 7 0.076 37
TPP2_ENST00000376065 TPP2 P29144 Tripeptidyl-peptidase 2 chr13 GO:0006508 Not Cancer Driver No 147 0.118 218 40 0.183 1
TPSAB1 TPSAB1 Q15661 Tryptase alpha/beta-1 chr16 GO:0006508 Not Cancer Driver No 40 0.145 28 6 0.214 0
TPSB2 TPSB2 P20231 Tryptase beta-2 chr16 GO:0006508 Not Cancer Driver No 21 0.076 28 0 0.0 0
TPSD1 TPSD1 Q9BZJ3 Tryptase delta chr16 GO:0006508 Not Cancer Driver No 50 0.207 34 5 0.147 0
TPSG1 TPSG1 Q9NRR2 Tryptase gamma chr16 GO:0006508 Not Cancer Driver No 48 0.15 52 7 0.135 0
TRABD2A TRABD2A Q86V40 Metalloprotease TIKI1 chr2 GO:0006508 Not Cancer Driver No 80 0.158 132 35 0.265 0
TRABD2B TRABD2B A6NFA1 Metalloprotease TIKI2 chr1 GO:0006508 Not Cancer Driver No 3 0.006 211 1 0.005 0
TRHDE TRHDE Q9UKU6 Thyrotropin-releasing hormone-degrading ectoenzyme chr12 GO:0006508 Not Cancer Driver No 346 0.338 104 11 0.106 0
TRIP4 TRIP4 Q15650 Activating signal cointegrator 1 chr15 GO:0006508 Not Cancer Driver No 71 0.122 176 27 0.153 0
TRPC4AP TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 GO:0006508 Not Cancer Driver No 84 0.105 70 7 0.1 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 GO:0006508 Census, Compendium Yes 554 0.144 402 59 0.147 8
TYSND1 TYSND1 Q2T9J0 Peroxisomal leader peptide-processing protease chr10 GO:0006508 Not Cancer Driver No 40 0.071 135 12 0.089 0
UBA3 UBA3 Q8TBC4 NEDD8-activating enzyme E1 catalytic subunit chr3 GO:0006508 Not Cancer Driver No 48 0.104 44 4 0.091 0
UBD UBD O15205 Ubiquitin D chr6 GO:0006508 Not Cancer Driver No 31 0.188 8 1 0.125 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0006508 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0006508 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0006508 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 GO:0006508 Not Cancer Driver No 170 0.097 165 15 0.091 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 GO:0006508 Not Cancer Driver No 172 0.098 228 30 0.132 0
UBR3 UBR3 Q6ZT12 E3 ubiquitin-protein ligase UBR3 chr2 GO:0006508 Not Cancer Driver No 154 0.082 339 28 0.083 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0006508 Not Cancer Driver No 26 0.085 100 7 0.07 0
UFSP2 UFSP2 Q9NUQ7 Ufm1-specific protease 2 chr4 GO:0006508 Not Cancer Driver No 53 0.113 22 3 0.136 2
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 GO:0006508 Not Cancer Driver No 169 0.109 161 20 0.124 0
UGGT2 UGGT2 Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 chr13 GO:0006508 Not Cancer Driver No 190 0.125 64 6 0.094 0
UIMC1_ENST00000511320 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 GO:0006508 Not Cancer Driver No 64 0.089 609 51 0.084 0
UNC5CL UNC5CL Q8IV45 UNC5C-like protein chr6 GO:0006508 Not Cancer Driver No 74 0.143 70 13 0.186 0
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 GO:0006508 Not Cancer Driver No 53 0.117 48 13 0.271 1
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0006508 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0006508 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0006508 Not Cancer Driver No 98 0.119 394 42 0.107 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0006508 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP1_ENST00000371146 USP1 O94782 Ubiquitin carboxyl-terminal hydrolase 1 chr1 GO:0006508 Not Cancer Driver No 63 0.08 403 30 0.074 0
USP22 USP22 Q9UPT9 Ubiquitin carboxyl-terminal hydrolase 22 chr17 GO:0006508 Not Cancer Driver No 64 0.122 50 1 0.02 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 GO:0006508 Not Cancer Driver No 135 0.128 354 55 0.155 0
USP30 USP30 Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 chr12 GO:0006508 Not Cancer Driver No 76 0.147 136 26 0.191 0
USP37_ENST00000454775 USP37 Q86T82 Ubiquitin carboxyl-terminal hydrolase 37 chr2 GO:0006508 Not Cancer Driver No 112 0.114 530 62 0.117 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0006508 Not Cancer Driver No 137 0.1 425 39 0.092 0
USP49 USP49 Q70CQ1 Ubiquitin carboxyl-terminal hydrolase 49 chr6 GO:0006508 Not Cancer Driver No 81 0.118 190 19 0.1 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0006508 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX GO:0006508 Census, Compendium Yes 339 0.133 405 51 0.126 1
USPL1 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 GO:0006508 Not Cancer Driver No 107 0.098 578 55 0.095 0
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 GO:0006508 Not Cancer Driver No 39 0.107 215 18 0.084 0
VASH2 VASH2 Q86V25 Tubulinyl-Tyr carboxypeptidase 2 chr1 GO:0006508 Not Cancer Driver No 32 0.09 106 9 0.085 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0006508 Not Cancer Driver No 88 0.109 186 16 0.086 16
VCPIP1 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 GO:0006508 Not Cancer Driver No 133 0.109 543 61 0.112 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0006508 Census, Compendium Yes 142 0.667 117 36 0.308 133
VPS4A VPS4A Q9UN37 Vacuolar protein sorting-associated protein 4A chr16 GO:0006508 Not Cancer Driver No 48 0.11 167 17 0.102 4
VPS4B VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 GO:0006508 Not Cancer Driver No 52 0.117 195 22 0.113 0
WFDC2 WFDC2 Q14508 WAP four-disulfide core domain protein 2 chr20 GO:0006508 Not Cancer Driver No 16 0.129 0 0 0.0 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0006508 Not Cancer Driver No 29 0.078 25 0 0.0 8
XPNPEP2 XPNPEP2 O43895 Xaa-Pro aminopeptidase 2 chrX GO:0006508 Not Cancer Driver No 114 0.169 16 2 0.125 0
XPNPEP3 XPNPEP3 Q9NQH7 Xaa-Pro aminopeptidase 3 chr22 GO:0006508 Not Cancer Driver No 64 0.126 128 14 0.109 1
YBEY_ENST00000397691 YBEY P58557 Endoribonuclease YbeY chr21 GO:0006508 Not Cancer Driver No 19 0.114 9 2 0.222 0
YIPF5 YIPF5 Q969M3 Protein YIPF5 chr5 GO:0006508 Not Cancer Driver No 23 0.089 57 6 0.105 1
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 GO:0006508 Not Cancer Driver No 112 0.145 136 14 0.103 1
YOD1 YOD1 Q5VVQ6 Ubiquitin thioesterase OTU1 chr1 GO:0006508 Not Cancer Driver No 30 0.086 120 6 0.05 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0006508 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 GO:0006508 Not Cancer Driver No 87 0.123 158 25 0.158 0
ZUP1 ZUP1 Q96AP4 Zinc finger-containing ubiquitin peptidase 1 chr6 GO:0006508 Not Cancer Driver No 63 0.109 204 19 0.093 0