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Total number of protein in "GO:0006446" GO term:  58

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0006446 Not Cancer Driver No 126 0.147 141 15 0.106 11
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0006446 Not Cancer Driver No 55 0.141 77 11 0.143 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0006446 Not Cancer Driver No 53 0.151 259 38 0.147 0
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0006446 Not Cancer Driver No 150 0.191 394 73 0.185 0
BZW1_ENST00000409600 BZW1 Q7L1Q6 eIF5-mimic protein 2 chr2 GO:0006446 Not Cancer Driver No 43 0.103 49 8 0.163 0
BZW2_ENST00000258761 BZW2 Q9Y6E2 eIF5-mimic protein 1 chr7 GO:0006446 Not Cancer Driver No 41 0.098 58 8 0.138 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0006446 Not Cancer Driver No 118 0.148 204 29 0.142 0
CTIF_ENST00000256413 CTIF O43310 CBP80/20-dependent translation initiation factor chr18 GO:0006446 Not Cancer Driver No 97 0.162 384 62 0.161 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0006446 Not Cancer Driver No 82 0.111 91 15 0.165 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0006446 Not Cancer Driver No 60 0.119 131 17 0.13 0
EIF1 EIF1 P41567 Eukaryotic translation initiation factor 1 chr17 GO:0006446 Not Cancer Driver No 13 0.115 9 1 0.111 0
EIF1B EIF1B O60739 Eukaryotic translation initiation factor 1b chr3 GO:0006446 Not Cancer Driver No 12 0.106 6 0 0.0 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0006446 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0006446 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0006446 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0006446 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 GO:0006446 Not Cancer Driver No 40 0.114 83 11 0.133 9
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0006446 Not Cancer Driver No 35 0.111 59 6 0.102 0
EIF3B_ENST00000397011 EIF3B P55884 Eukaryotic translation initiation factor 3 subunit B chr7 GO:0006446 Not Cancer Driver No 89 0.109 226 4 0.018 0
EIF3E EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 GO:0006446 Census, Compendium Yes 73 0.164 27 1 0.037 0
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 GO:0006446 Not Cancer Driver No 37 0.105 109 12 0.11 0
EIF3K EIF3K Q9UBQ5 Eukaryotic translation initiation factor 3 subunit K chr19 GO:0006446 Not Cancer Driver No 25 0.115 0 0 0.0 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 GO:0006446 Census Yes 77 0.189 27 14 0.519 0
EIF4B_ENST00000262056 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 GO:0006446 Not Cancer Driver No 94 0.154 589 90 0.153 0
EIF4EBP1 EIF4EBP1 Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 chr8 GO:0006446 Not Cancer Driver No 8 0.068 118 8 0.068 0
EIF4EBP2 EIF4EBP2 Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 chr10 GO:0006446 Not Cancer Driver No 17 0.142 118 14 0.119 0
EIF4EBP3 EIF4EBP3 O60516 Eukaryotic translation initiation factor 4E-binding protein 3 chr5 GO:0006446 Not Cancer Driver No 9 0.09 78 6 0.077 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0006446 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0006446 Not Cancer Driver No 104 0.115 382 43 0.113 0
EIF4G3_ENST00000264211 EIF4G3 O43432 Eukaryotic translation initiation factor 4 gamma 3 chr1 GO:0006446 Not Cancer Driver No 200 0.126 1018 127 0.125 0
EIF4H EIF4H Q15056 Eukaryotic translation initiation factor 4H chr7 GO:0006446 Not Cancer Driver No 30 0.121 175 17 0.097 0
EIF5B EIF5B O60841 Eukaryotic translation initiation factor 5B chr2 GO:0006446 Not Cancer Driver No 122 0.1 718 71 0.099 0
EIF5_ENST00000392715 EIF5 P55010 Eukaryotic translation initiation factor 5 chr14 GO:0006446 Not Cancer Driver No 64 0.148 185 23 0.124 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0006446 Not Cancer Driver No 124 0.196 327 70 0.214 3
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 GO:0006446 Not Cancer Driver No 64 0.092 299 29 0.097 3
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0006446 Not Cancer Driver No 10 0.049 118 8 0.068 20
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0006446 Not Cancer Driver No 49 0.153 84 12 0.143 0
KLHL25 KLHL25 Q9H0H3 Kelch-like protein 25 chr15 GO:0006446 Not Cancer Driver No 83 0.141 32 7 0.219 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0006446 Not Cancer Driver No 74 0.128 274 29 0.106 0
MIF4GD_ENST00000325102 MIF4GD A9UHW6 MIF4G domain-containing protein chr17 GO:0006446 Not Cancer Driver No 23 0.104 12 1 0.083 0
MTIF2_ENST00000403721 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 GO:0006446 Not Cancer Driver No 101 0.139 112 9 0.08 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0006446 Census, Compendium Yes 379 0.149 296 37 0.125 18
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0006446 Not Cancer Driver No 88 0.111 89 8 0.09 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0006446 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0006446 Not Cancer Driver No 89 0.234 88 19 0.216 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0006446 Census, Compendium Yes 29 0.099 249 22 0.088 0
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:0006446 Not Cancer Driver No 67 0.14 259 36 0.139 0
PAIP2B PAIP2B Q9ULR5 Polyadenylate-binding protein-interacting protein 2B chr2 GO:0006446 Not Cancer Driver No 16 0.13 123 16 0.13 0
PAIP2_ENST00000265192 PAIP2 Q9BPZ3 Polyadenylate-binding protein-interacting protein 2 chr5 GO:0006446 Not Cancer Driver No 11 0.087 88 10 0.114 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0006446 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0006446 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0006446 Not Cancer Driver No 72 0.101 415 45 0.108 1
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 GO:0006446 Not Cancer Driver No 40 0.11 129 12 0.093 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 GO:0006446 Not Cancer Driver No 27 0.133 33 2 0.061 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0006446 Not Cancer Driver No 24 0.119 25 4 0.16 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0006446 Not Cancer Driver No 24 0.103 45 3 0.067 0
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0006446 Census Yes 311 0.132 1990 266 0.134 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0006446 Not Cancer Driver No 67 0.116 376 44 0.117 0