Total number of protein in "GO:0006401" GO term: 83
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ANG | ANG | P03950 | Angiogenin | chr14 | GO:0006401 | Not Cancer Driver | No | 19 | 0.129 | 36 | 2 | 0.056 | 14 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0006401 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| CNOT6_ENST00000261951 | CNOT6 | Q9ULM6 | CCR4-NOT transcription complex subunit 6 | chr5 | GO:0006401 | Not Cancer Driver | No | 65 | 0.117 | 66 | 4 | 0.061 | 0 |
| CNOT7 | CNOT7 | Q9UIV1 | CCR4-NOT transcription complex subunit 7 | chr8 | GO:0006401 | Not Cancer Driver | No | 31 | 0.109 | 21 | 1 | 0.048 | 0 |
| CNOT8 | CNOT8 | Q9UFF9 | CCR4-NOT transcription complex subunit 8 | chr5 | GO:0006401 | Not Cancer Driver | No | 30 | 0.103 | 6 | 0 | 0.0 | 0 |
| CSDE1_ENST00000358528 | CSDE1 | O75534 | Cold shock domain-containing protein E1 | chr1 | GO:0006401 | Not Cancer Driver | No | 118 | 0.148 | 204 | 29 | 0.142 | 0 |
| DCP2 | DCP2 | Q8IU60 | m7GpppN-mRNA hydrolase | chr5 | GO:0006401 | Not Cancer Driver | No | 57 | 0.136 | 167 | 24 | 0.144 | 0 |
| DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | GO:0006401 | Not Cancer Driver | No | 48 | 0.142 | 53 | 6 | 0.113 | 1 |
| DEDD2 | DEDD2 | Q8WXF8 | DNA-binding death effector domain-containing protein 2 | chr19 | GO:0006401 | Not Cancer Driver | No | 42 | 0.129 | 133 | 25 | 0.188 | 0 |
| DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | GO:0006401 | Census, Compendium | Yes | 264 | 0.137 | 362 | 45 | 0.124 | 4 |
| DIS3 | DIS3 | Q9Y2L1 | Exosome complex exonuclease RRP44 | chr13 | GO:0006401 | Compendium | Yes | 121 | 0.126 | 235 | 32 | 0.136 | 0 |
| DIS3L | DIS3L | Q8TF46 | DIS3-like exonuclease 1 | chr15 | GO:0006401 | Not Cancer Driver | No | 111 | 0.105 | 139 | 20 | 0.144 | 0 |
| DIS3L2 | DIS3L2 | Q8IYB7 | DIS3-like exonuclease 2 | chr2 | GO:0006401 | Not Cancer Driver | No | 114 | 0.129 | 264 | 22 | 0.083 | 1 |
| DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0006401 | Not Cancer Driver | No | 120 | 0.113 | 52 | 8 | 0.154 | 3 |
| DROSHA_ENST00000344624 | DROSHA | Q9NRR4 | Ribonuclease 3 | chr5 | GO:0006401 | Census, Compendium | Yes | 175 | 0.127 | 682 | 100 | 0.147 | 0 |
| DXO_ENST00000375356 | DXO | O77932 | Decapping and exoribonuclease protein | chr6 | GO:0006401 | Not Cancer Driver | No | 46 | 0.116 | 143 | 17 | 0.119 | 0 |
| ELAC2 | ELAC2 | Q9BQ52 | Zinc phosphodiesterase ELAC protein 2 | chr17 | GO:0006401 | Not Cancer Driver | No | 86 | 0.104 | 208 | 30 | 0.144 | 10 |
| ERI1_ENST00000519292 | ERI1 | Q8IV48 | 3'-5' exoribonuclease 1 | chr8 | GO:0006401 | Not Cancer Driver | No | 40 | 0.115 | 78 | 13 | 0.167 | 0 |
| ERN2 | ERN2 | Q76MJ5 | Serine/threonine-protein kinase/endoribonuclease IRE2 | chr16 | GO:0006401 | Not Cancer Driver | No | 192 | 0.207 | 213 | 45 | 0.211 | 0 |
| EXOSC1 | EXOSC1 | Q9Y3B2 | Exosome complex component CSL4 | chr10 | GO:0006401 | Not Cancer Driver | No | 14 | 0.072 | 14 | 2 | 0.143 | 1 |
| EXOSC10 | EXOSC10 | Q01780 | Exosome component 10 | chr1 | GO:0006401 | Not Cancer Driver | No | 87 | 0.098 | 375 | 35 | 0.093 | 0 |
| EXOSC2 | EXOSC2 | Q13868 | Exosome complex component RRP4 | chr9 | GO:0006401 | Not Cancer Driver | No | 21 | 0.072 | 47 | 6 | 0.128 | 2 |
| EXOSC3 | EXOSC3 | Q9NQT5 | Exosome complex component RRP40 | chr9 | GO:0006401 | Not Cancer Driver | No | 18 | 0.065 | 54 | 2 | 0.037 | 4 |
| EXOSC4 | EXOSC4 | Q9NPD3 | Exosome complex component RRP41 | chr8 | GO:0006401 | Not Cancer Driver | No | 34 | 0.139 | 23 | 0 | 0.0 | 0 |
| EXOSC5 | EXOSC5 | Q9NQT4 | Exosome complex component RRP46 | chr19 | GO:0006401 | Not Cancer Driver | No | 43 | 0.183 | 31 | 3 | 0.097 | 0 |
| EXOSC6 | EXOSC6 | Q5RKV6 | Exosome complex component MTR3 | chr16 | GO:0006401 | Not Cancer Driver | No | 3 | 0.011 | 102 | 0 | 0.0 | 0 |
| EXOSC7 | EXOSC7 | Q15024 | Exosome complex component RRP42 | chr3 | GO:0006401 | Not Cancer Driver | No | 41 | 0.141 | 8 | 1 | 0.125 | 0 |
| EXOSC8 | EXOSC8 | Q96B26 | Exosome complex component RRP43 | chr13 | GO:0006401 | Not Cancer Driver | No | 20 | 0.072 | 28 | 1 | 0.036 | 2 |
| EXOSC9_ENST00000243498 | EXOSC9 | Q06265 | Exosome complex component RRP45 | chr4 | GO:0006401 | Not Cancer Driver | No | 58 | 0.132 | 154 | 18 | 0.117 | 1 |
| FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0006401 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
| HNRNPD | HNRNPD | Q14103 | Heterogeneous nuclear ribonucleoprotein D0 | chr4 | GO:0006401 | Not Cancer Driver | No | 39 | 0.11 | 206 | 19 | 0.092 | 0 |
| ISG20 | ISG20 | Q96AZ6 | Interferon-stimulated gene 20 kDa protein | chr15 | GO:0006401 | Not Cancer Driver | No | 20 | 0.11 | 6 | 0 | 0.0 | 0 |
| LIN28A_ENST00000254231 | LIN28A | Q9H9Z2 | Protein lin-28 homolog A | chr1 | GO:0006401 | Not Cancer Driver | No | 37 | 0.177 | 86 | 12 | 0.14 | 0 |
| LIN28B | LIN28B | Q6ZN17 | Protein lin-28 homolog B | chr6 | GO:0006401 | Not Cancer Driver | No | 60 | 0.24 | 179 | 32 | 0.179 | 0 |
| LSM1 | LSM1 | O15116 | U6 snRNA-associated Sm-like protein LSm1 | chr8 | GO:0006401 | Not Cancer Driver | No | 21 | 0.158 | 6 | 1 | 0.167 | 0 |
| MRPL44 | MRPL44 | Q9H9J2 | 39S ribosomal protein L44, mitochondrial | chr2 | GO:0006401 | Not Cancer Driver | No | 37 | 0.111 | 45 | 2 | 0.044 | 1 |
| MTPAP | MTPAP | Q9NVV4 | Poly(A) RNA polymerase, mitochondrial | chr10 | GO:0006401 | Not Cancer Driver | No | 73 | 0.125 | 136 | 22 | 0.162 | 1 |
| MTREX | MTREX | P42285 | Exosome RNA helicase MTR4 | chr5 | GO:0006401 | Not Cancer Driver | No | 117 | 0.112 | 160 | 15 | 0.094 | 0 |
| NCBP1 | NCBP1 | Q09161 | Nuclear cap-binding protein subunit 1 | chr9 | GO:0006401 | Not Cancer Driver | No | 88 | 0.111 | 89 | 8 | 0.09 | 0 |
| NT5C3B | NT5C3B | Q969T7 | 7-methylguanosine phosphate-specific 5'-nucleotidase | chr17 | GO:0006401 | Not Cancer Driver | No | 25 | 0.083 | 2 | 0 | 0.0 | 0 |
| NUDT16L1 | NUDT16L1 | Q9BRJ7 | Tudor-interacting repair regulator protein | chr16 | GO:0006401 | Not Cancer Driver | No | 16 | 0.076 | 6 | 0 | 0.0 | 0 |
| NUDT16_ENST00000521288 | NUDT16 | Q96DE0 | U8 snoRNA-decapping enzyme | chr3 | GO:0006401 | Not Cancer Driver | No | 29 | 0.149 | 8 | 1 | 0.125 | 0 |
| OAS2 | OAS2 | P29728 | 2'-5'-oligoadenylate synthase 2 | chr12 | GO:0006401 | Not Cancer Driver | No | 141 | 0.196 | 47 | 14 | 0.298 | 0 |
| PABPC4_ENST00000372857 | PABPC4 | Q13310 | Polyadenylate-binding protein 4 | chr1 | GO:0006401 | Not Cancer Driver | No | 89 | 0.138 | 253 | 49 | 0.194 | 0 |
| PARN | PARN | O95453 | Poly(A)-specific ribonuclease PARN | chr16 | GO:0006401 | Not Cancer Driver | No | 71 | 0.111 | 197 | 22 | 0.112 | 2 |
| PCID2_ENST00000375479 | PCID2 | Q5JVF3 | PCI domain-containing protein 2 | chr13 | GO:0006401 | Not Cancer Driver | No | 46 | 0.115 | 13 | 5 | 0.385 | 0 |
| PDE12 | PDE12 | Q6L8Q7 | 2',5'-phosphodiesterase 12 | chr3 | GO:0006401 | Not Cancer Driver | No | 59 | 0.097 | 129 | 8 | 0.062 | 0 |
| PELO | PELO | Q9BRX2 | Protein pelota homolog | chr5 | GO:0006401 | Not Cancer Driver | No | 38 | 0.099 | 67 | 10 | 0.149 | 0 |
| PNPT1 | PNPT1 | Q8TCS8 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial | chr2 | GO:0006401 | Not Cancer Driver | No | 86 | 0.11 | 115 | 10 | 0.087 | 2 |
| POLR2G | POLR2G | P62487 | DNA-directed RNA polymerase II subunit RPB7 | chr11 | GO:0006401 | Not Cancer Driver | No | 15 | 0.087 | 15 | 1 | 0.067 | 0 |
| POP1_ENST00000349693 | POP1 | Q99575 | Ribonucleases P/MRP protein subunit POP1 | chr8 | GO:0006401 | Not Cancer Driver | No | 161 | 0.157 | 495 | 75 | 0.152 | 3 |
| PPP1R8 | PPP1R8 | Q12972 | Nuclear inhibitor of protein phosphatase 1 | chr1 | GO:0006401 | Not Cancer Driver | No | 24 | 0.068 | 251 | 19 | 0.076 | 0 |
| PRPF18 | PRPF18 | Q99633 | Pre-mRNA-splicing factor 18 | chr10 | GO:0006401 | Not Cancer Driver | No | 52 | 0.152 | 93 | 18 | 0.194 | 0 |
| RBM7_ENST00000540163 | RBM7 | Q9Y580 | RNA-binding protein 7 | chr11 | GO:0006401 | Not Cancer Driver | No | 36 | 0.135 | 194 | 27 | 0.139 | 0 |
| RNASE2 | RNASE2 | P10153 | Non-secretory ribonuclease | chr14 | GO:0006401 | Not Cancer Driver | No | 30 | 0.186 | 20 | 4 | 0.2 | 0 |
| RNASE3 | RNASE3 | P12724 | Eosinophil cationic protein | chr14 | GO:0006401 | Not Cancer Driver | No | 37 | 0.231 | 8 | 0 | 0.0 | 0 |
| RNASE6 | RNASE6 | Q93091 | Ribonuclease K6 | chr14 | GO:0006401 | Not Cancer Driver | No | 26 | 0.173 | 0 | 0 | 0.0 | 0 |
| RNASEH1 | RNASEH1 | O60930 | Ribonuclease H1 | chr2 | GO:0006401 | Not Cancer Driver | No | 33 | 0.115 | 124 | 20 | 0.161 | 2 |
| RNASEH2A | RNASEH2A | O75792 | Ribonuclease H2 subunit A | chr19 | GO:0006401 | Not Cancer Driver | No | 42 | 0.14 | 31 | 3 | 0.097 | 7 |
| RNASEH2B | RNASEH2B | Q5TBB1 | Ribonuclease H2 subunit B | chr13 | GO:0006401 | Not Cancer Driver | No | 34 | 0.109 | 84 | 9 | 0.107 | 14 |
| RNASEH2C | RNASEH2C | Q8TDP1 | Ribonuclease H2 subunit C | chr11 | GO:0006401 | Not Cancer Driver | No | 6 | 0.037 | 80 | 2 | 0.025 | 7 |
| RNASET2_ENST00000476238 | RNASET2 | O00584 | Ribonuclease T2 | chr6 | GO:0006401 | Not Cancer Driver | No | 32 | 0.125 | 37 | 3 | 0.081 | 1 |
| SIDT2_ENST00000620360 | SIDT2 | Q8NBJ9 | SID1 transmembrane family member 2 | chr11 | GO:0006401 | Not Cancer Driver | No | 113 | 0.136 | 23 | 6 | 0.261 | 0 |
| SKIV2L | SKIV2L | Q15477 | Helicase SKI2W | chr6 | GO:0006401 | Not Cancer Driver | No | 140 | 0.112 | 390 | 54 | 0.138 | 1 |
| SLFN13 | SLFN13 | Q68D06 | Schlafen family member 13 | chr17 | GO:0006401 | Not Cancer Driver | No | 152 | 0.169 | 45 | 5 | 0.111 | 0 |
| SLFN14 | SLFN14 | P0C7P3 | Protein SLFN14 | chr17 | GO:0006401 | Not Cancer Driver | No | 66 | 0.072 | 61 | 3 | 0.049 | 4 |
| SND1 | SND1 | Q7KZF4 | Staphylococcal nuclease domain-containing protein 1 | chr7 | GO:0006401 | Census | Yes | 127 | 0.14 | 258 | 48 | 0.186 | 0 |
| SSB | SSB | P05455 | Lupus La protein | chr2 | GO:0006401 | Not Cancer Driver | No | 39 | 0.096 | 181 | 18 | 0.099 | 0 |
| SUPV3L1 | SUPV3L1 | Q8IYB8 | ATP-dependent RNA helicase SUPV3L1, mitochondrial | chr10 | GO:0006401 | Not Cancer Driver | No | 72 | 0.092 | 140 | 12 | 0.086 | 0 |
| TENT2_ENST00000428308 | TENT2 | Q6PIY7 | Poly(A) RNA polymerase GLD2 | chr5 | GO:0006401 | Not Cancer Driver | No | 65 | 0.134 | 75 | 15 | 0.2 | 0 |
| TRIR | TRIR | Q9BQ61 | Telomerase RNA component interacting RNase | chr19 | GO:0006401 | Not Cancer Driver | No | 17 | 0.097 | 176 | 17 | 0.097 | 0 |
| TTC37 | TTC37 | Q6PGP7 | Tetratricopeptide repeat protein 37 | chr5 | GO:0006401 | Not Cancer Driver | No | 164 | 0.105 | 59 | 3 | 0.051 | 3 |
| TUT1_ENST00000476907 | TUT1 | Q9H6E5 | Speckle targeted PIP5K1A-regulated poly(A) polymerase | chr11 | GO:0006401 | Not Cancer Driver | No | 97 | 0.111 | 410 | 50 | 0.122 | 0 |
| TUT4_ENST00000371544 | TUT4 | Q5TAX3 | Terminal uridylyltransferase 4 | chr1 | GO:0006401 | Not Cancer Driver | No | 187 | 0.114 | 771 | 102 | 0.132 | 0 |
| TUT7 | TUT7 | Q5VYS8 | Terminal uridylyltransferase 7 | chr9 | GO:0006401 | Not Cancer Driver | No | 159 | 0.106 | 659 | 74 | 0.112 | 0 |
| UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0006401 | Not Cancer Driver | No | 146 | 0.129 | 329 | 36 | 0.109 | 0 |
| XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | GO:0006401 | Not Cancer Driver | No | 213 | 0.125 | 577 | 65 | 0.113 | 0 |
| XRN2 | XRN2 | Q9H0D6 | 5'-3' exoribonuclease 2 | chr20 | GO:0006401 | Not Cancer Driver | No | 129 | 0.136 | 427 | 63 | 0.148 | 0 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0006401 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
| ZCCHC8 | ZCCHC8 | Q6NZY4 | Zinc finger CCHC domain-containing protein 8 | chr12 | GO:0006401 | Census | Yes | 81 | 0.115 | 503 | 56 | 0.111 | 1 |
| ZFP36 | ZFP36 | P26651 | mRNA decay activator protein ZFP36 | chr19 | GO:0006401 | Not Cancer Driver | No | 43 | 0.132 | 262 | 34 | 0.13 | 0 |
| ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0006401 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |
| ZPR1 | ZPR1 | O75312 | Zinc finger protein ZPR1 | chr11 | GO:0006401 | Not Cancer Driver | No | 38 | 0.083 | 291 | 27 | 0.093 | 0 |