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Total number of protein in "GO:0006310" GO term:  101

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 GO:0006310 Not Cancer Driver No 61 0.142 74 15 0.203 0
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 GO:0006310 Not Cancer Driver No 63 0.104 163 23 0.141 0
ACTR8 ACTR8 Q9H981 Actin-related protein 8 chr3 GO:0006310 Not Cancer Driver No 61 0.098 239 21 0.088 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0006310 Not Cancer Driver No 56 0.283 0 0 0.0 8
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0006310 Not Cancer Driver No 34 0.107 103 14 0.136 0
APEX2 APEX2 Q9UBZ4 DNA-(apurinic or apyrimidinic site) endonuclease 2 chrX GO:0006310 Not Cancer Driver No 66 0.127 148 14 0.095 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0006310 Not Cancer Driver No 200 0.108 1075 112 0.104 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0006310 Not Cancer Driver No 28 0.224 119 25 0.21 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0006310 Census, Compendium Yes 156 0.174 699 114 0.163 2
BLM BLM P54132 Bloom syndrome protein chr15 GO:0006310 Census Yes 153 0.108 667 70 0.105 8
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0006310 Census, Compendium Yes 457 0.134 1542 225 0.146 46
CCDC36_ENST00000452691 IHO1 Q8IYA8 Interactor of HORMAD1 protein 1 chr3 GO:0006310 Not Cancer Driver No 83 0.14 355 43 0.121 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0006310 Not Cancer Driver No 56 0.15 13 2 0.154 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0006310 Not Cancer Driver No 56 0.215 24 7 0.292 32
CYREN CYREN Q9BWK5 Cell cycle regulator of non-homologous end joining chr7 GO:0006310 Not Cancer Driver No 24 0.153 128 19 0.148 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0006310 Not Cancer Driver No 11 0.037 61 1 0.016 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0006310 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0006310 Census Yes 120 0.131 225 27 0.12 15
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0006310 Not Cancer Driver No 123 0.145 472 76 0.161 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0006310 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0006310 Not Cancer Driver No 3 0.011 102 0 0.0 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0006310 Not Cancer Driver No 109 0.127 24 5 0.208 0
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0006310 Not Cancer Driver No 268 0.131 898 128 0.143 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0006310 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB3 HMGB3 O15347 High mobility group protein B3 chrX GO:0006310 Not Cancer Driver No 37 0.185 182 32 0.176 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0006310 Not Cancer Driver No 61 0.106 82 6 0.073 2
IGHMBP2 IGHMBP2 P38935 DNA-binding protein SMUBP-2 chr11 GO:0006310 Not Cancer Driver No 136 0.137 354 53 0.15 31
INO80B INO80B Q9C086 INO80 complex subunit B chr2 GO:0006310 Not Cancer Driver No 35 0.098 336 33 0.098 0
INO80C_ENST00000334598 INO80C Q6PI98 INO80 complex subunit C chr18 GO:0006310 Not Cancer Driver No 18 0.094 109 11 0.101 0
INO80D INO80D Q53TQ3 INO80 complex subunit D chr2 GO:0006310 Not Cancer Driver No 110 0.107 738 93 0.126 0
INO80E INO80E Q8NBZ0 INO80 complex subunit E chr16 GO:0006310 Not Cancer Driver No 21 0.086 210 21 0.1 0
KIN KIN O60870 DNA/RNA-binding protein KIN17 chr10 GO:0006310 Not Cancer Driver No 52 0.132 137 13 0.095 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0006310 Census Yes 64 0.16 370 57 0.154 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0006310 Not Cancer Driver No 134 0.147 63 10 0.159 2
MCM8_ENST00000378896 MCM8 Q9UJA3 DNA helicase MCM8 chr20 GO:0006310 Not Cancer Driver No 94 0.112 188 19 0.101 1
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 GO:0006310 Not Cancer Driver No 56 0.049 523 13 0.025 0
MCRS1_ENST00000550165 MCRS1 Q96EZ8 Microspherule protein 1 chr12 GO:0006310 Not Cancer Driver No 72 0.156 151 18 0.119 0
MEI4 MEI4 A8MW99 Meiosis-specific protein MEI4 chr6 GO:0006310 Not Cancer Driver No 0 0.0 69 0 0.0 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0006310 Census Yes 92 0.122 208 22 0.106 85
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0006310 Not Cancer Driver No 84 0.119 292 35 0.12 1
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0006310 Census Yes 92 0.099 37 4 0.108 70
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0006310 Census Yes 154 0.113 386 41 0.106 6
NBN NBN O60934 Nibrin chr8 GO:0006310 Census Yes 90 0.119 417 54 0.129 1
NFRKB_ENST00000446488 NFRKB Q6P4R8 Nuclear factor related to kappa-B-binding protein chr11 GO:0006310 Not Cancer Driver No 128 0.099 838 74 0.088 0
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0006310 Not Cancer Driver No 35 0.117 83 8 0.096 2
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0006310 Compendium Yes 353 0.126 1528 184 0.12 37
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:0006310 Census, Compendium Yes 101 0.214 349 64 0.183 0
NSMCE2_ENST00000522563 NSMCE2 Q96MF7 E3 SUMO-protein ligase NSE2 chr8 GO:0006310 Not Cancer Driver No 30 0.121 119 12 0.101 0
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0006310 Not Cancer Driver No 30 0.123 243 30 0.123 0
PAGR1 PAGR1 Q9BTK6 PAXIP1-associated glutamate-rich protein 1 chr16 GO:0006310 Not Cancer Driver No 16 0.063 254 16 0.063 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0006310 Not Cancer Driver No 120 0.112 461 39 0.085 0
PGBD5 PGBD5 Q8N414 PiggyBac transposable element-derived protein 5 chr1 GO:0006310 Not Cancer Driver No 73 0.139 126 1 0.008 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0006310 Not Cancer Driver No 54 0.084 209 11 0.053 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0006310 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLM_ENST00000242248 POLM Q9NP87 DNA-directed DNA/RNA polymerase mu chr7 GO:0006310 Not Cancer Driver No 57 0.115 187 16 0.086 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0006310 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0006310 Not Cancer Driver No 538 0.13 421 61 0.145 2
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0006310 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAD21L1 RAD21L1 Q9H4I0 Double-strand-break repair protein rad21-like protein 1 chr20 GO:0006310 Not Cancer Driver No 37 0.067 186 5 0.027 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0006310 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51B_ENST00000487270 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0006310 Census Yes 45 0.117 13 0 0.0 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:0006310 Not Cancer Driver No 47 0.125 18 2 0.111 6
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 GO:0006310 Not Cancer Driver No 34 0.104 49 10 0.204 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0006310 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 GO:0006310 Not Cancer Driver No 41 0.098 251 30 0.12 0
RAD54L_ENST00000442598 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0006310 Not Cancer Driver No 79 0.106 124 13 0.105 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0006310 Not Cancer Driver No 204 0.196 208 43 0.207 36
REC114 REC114 Q7Z4M0 Meiotic recombination protein REC114 chr15 GO:0006310 Not Cancer Driver No 31 0.117 84 10 0.119 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:0006310 Not Cancer Driver No 60 0.11 244 26 0.107 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 GO:0006310 Census, Compendium Yes 138 0.114 608 71 0.117 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0006310 Not Cancer Driver No 132 0.133 495 71 0.143 0
RECQL_ENST00000421138 RECQL P46063 ATP-dependent DNA helicase Q1 chr12 GO:0006310 Not Cancer Driver No 67 0.103 91 5 0.055 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0006310 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF212 RNF212 Q495C1 Probable E3 SUMO-protein ligase RNF212 chr4 GO:0006310 Not Cancer Driver No 36 0.121 58 12 0.207 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0006310 Not Cancer Driver No 56 0.115 226 29 0.128 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 GO:0006310 Not Cancer Driver No 51 0.083 98 6 0.061 0
RPAIN_ENST00000381209 RPAIN Q86UA6 RPA-interacting protein chr17 GO:0006310 Not Cancer Driver No 31 0.142 31 5 0.161 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0006310 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0006310 Not Cancer Driver No 62 0.134 100 13 0.13 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0006310 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0006310 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0006310 Not Cancer Driver No 128 0.117 458 57 0.124 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0006310 Not Cancer Driver No 72 0.092 140 12 0.086 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0006310 Not Cancer Driver No 44 0.075 271 18 0.066 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0006310 Census Yes 52 0.08 649 52 0.08 0
TEP1 TEP1 Q99973 Telomerase protein component 1 chr14 GO:0006310 Not Cancer Driver No 332 0.126 396 67 0.169 0
TEX11_ENST00000344304 TEX11 Q8IYF3 Testis-expressed protein 11 chrX GO:0006310 Not Cancer Driver No 139 0.148 30 3 0.1 2
TFPT TFPT P0C1Z6 TCF3 fusion partner chr19 GO:0006310 Census Yes 41 0.162 237 41 0.173 0
THAP9 THAP9 Q9H5L6 DNA transposase THAP9 chr4 GO:0006310 Not Cancer Driver No 82 0.091 46 6 0.13 0
TPRKB_ENST00000272424 TPRKB Q9Y3C4 EKC/KEOPS complex subunit TPRKB chr2 GO:0006310 Not Cancer Driver No 20 0.114 0 0 0.0 2
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0006310 Not Cancer Driver No 26 0.083 98 10 0.102 18
TSN TSN Q15631 Translin chr2 GO:0006310 Not Cancer Driver No 30 0.132 0 0 0.0 0
UCHL5 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 GO:0006310 Not Cancer Driver No 33 0.1 41 7 0.171 0
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0006310 Not Cancer Driver No 34 0.109 96 13 0.135 1
VRTN VRTN Q9H8Y1 Vertnin chr14 GO:0006310 Not Cancer Driver No 153 0.218 132 27 0.205 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0006310 Census, Compendium Yes 164 0.115 373 41 0.11 2
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0006310 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0006310 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 GO:0006310 Not Cancer Driver No 47 0.14 171 31 0.181 3
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0006310 Not Cancer Driver No 87 0.119 118 11 0.093 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0006310 Not Cancer Driver No 37 0.089 336 26 0.077 2