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Total number of protein in "GO:0006284" GO term:  28

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0006284 Not Cancer Driver No 34 0.107 103 14 0.136 0
APEX2 APEX2 Q9UBZ4 DNA-(apurinic or apyrimidinic site) endonuclease 2 chrX GO:0006284 Not Cancer Driver No 66 0.127 148 14 0.095 0
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0006284 Not Cancer Driver No 120 0.113 52 8 0.154 3
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0006284 Not Cancer Driver No 211 0.141 829 117 0.141 9
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0006284 Census Yes 12 0.11 109 12 0.11 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0006284 Not Cancer Driver No 669 0.153 2091 329 0.157 21
LIG1 LIG1 P18858 DNA ligase 1 chr19 GO:0006284 Not Cancer Driver No 137 0.149 397 62 0.156 0
MPG MPG P29372 DNA-3-methyladenine glycosylase chr16 GO:0006284 Not Cancer Driver No 35 0.117 141 21 0.149 0
MUTYH MUTYH Q9UIF7 Adenine DNA glycosylase chr1 GO:0006284 Census Yes 90 0.165 198 29 0.146 23
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0006284 Not Cancer Driver No 41 0.105 165 14 0.085 0
NEIL2 NEIL2 Q969S2 Endonuclease 8-like 2 chr8 GO:0006284 Not Cancer Driver No 31 0.093 145 14 0.097 0
NEIL3 NEIL3 Q8TAT5 Endonuclease 8-like 3 chr4 GO:0006284 Not Cancer Driver No 80 0.132 131 18 0.137 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0006284 Not Cancer Driver No 37 0.107 71 12 0.169 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 GO:0006284 Not Cancer Driver No 74 0.127 172 23 0.134 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0006284 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLQ POLQ O75417 DNA polymerase theta chr3 GO:0006284 Census, Compendium Yes 364 0.141 949 135 0.142 0
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 GO:0006284 Not Cancer Driver No 43 0.115 71 7 0.099 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 GO:0006284 Not Cancer Driver No 51 0.083 98 6 0.061 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0006284 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPA3 RPA3 P35244 Replication protein A 14 kDa subunit chr7 GO:0006284 Not Cancer Driver No 13 0.107 4 1 0.25 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0006284 Not Cancer Driver No 33 0.093 164 12 0.073 0
SMUG1 SMUG1 Q53HV7 Single-strand selective monofunctional uracil DNA glycosylase chr12 GO:0006284 Not Cancer Driver No 33 0.122 46 2 0.043 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0006284 Not Cancer Driver No 75 0.183 185 31 0.168 0
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0006284 Not Cancer Driver No 34 0.109 96 13 0.135 1
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0006284 Not Cancer Driver No 137 0.1 425 39 0.092 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0006284 Census, Compendium Yes 164 0.115 373 41 0.11 2
XPA XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:0006284 Census Yes 27 0.099 121 13 0.107 5
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0006284 Not Cancer Driver No 85 0.134 426 53 0.124 1