Total number of protein in "GO:0006281" GO term: 289
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTL6A | ACTL6A | O96019 | Actin-like protein 6A | chr3 | GO:0006281 | Not Cancer Driver | No | 61 | 0.142 | 74 | 15 | 0.203 | 0 |
ACTR5 | ACTR5 | Q9H9F9 | Actin-related protein 5 | chr20 | GO:0006281 | Not Cancer Driver | No | 63 | 0.104 | 163 | 23 | 0.141 | 0 |
ADPRHL2 | ADPRS | Q9NX46 | ADP-ribosylhydrolase ARH3 | chr1 | GO:0006281 | Not Cancer Driver | No | 32 | 0.088 | 49 | 4 | 0.082 | 1 |
ALKBH1 | ALKBH1 | Q13686 | Nucleic acid dioxygenase ALKBH1 | chr14 | GO:0006281 | Not Cancer Driver | No | 55 | 0.141 | 77 | 11 | 0.143 | 0 |
ALKBH3 | ALKBH3 | Q96Q83 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 | chr11 | GO:0006281 | Not Cancer Driver | No | 42 | 0.147 | 157 | 25 | 0.159 | 0 |
APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0006281 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
APLF | APLF | Q8IW19 | Aprataxin and PNK-like factor | chr2 | GO:0006281 | Not Cancer Driver | No | 64 | 0.125 | 407 | 57 | 0.14 | 0 |
APTX_ENST00000379819 | APTX | Q7Z2E3 | Aprataxin | chr9 | GO:0006281 | Not Cancer Driver | No | 36 | 0.101 | 101 | 6 | 0.059 | 9 |
ASCC1_ENST00000394915 | ASCC1 | Q8N9N2 | Activating signal cointegrator 1 complex subunit 1 | chr10 | GO:0006281 | Not Cancer Driver | No | 39 | 0.098 | 92 | 9 | 0.098 | 0 |
ASCC2 | ASCC2 | Q9H1I8 | Activating signal cointegrator 1 complex subunit 2 | chr22 | GO:0006281 | Not Cancer Driver | No | 87 | 0.115 | 326 | 34 | 0.104 | 0 |
ASF1A | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | GO:0006281 | Not Cancer Driver | No | 18 | 0.088 | 69 | 2 | 0.029 | 0 |
ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:0006281 | Census, Compendium | Yes | 338 | 0.128 | 106 | 14 | 0.132 | 1 |
ATRIP | ATRIP | Q8WXE1 | ATR-interacting protein | chr3 | GO:0006281 | Not Cancer Driver | No | 76 | 0.096 | 383 | 32 | 0.084 | 0 |
ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0006281 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
BACH1_ENST00000286800 | BACH1 | O14867 | Transcription regulator protein BACH1 | chr21 | GO:0006281 | Not Cancer Driver | No | 105 | 0.143 | 328 | 39 | 0.119 | 0 |
BCCIP_ENST00000278100 | BCCIP | Q9P287 | BRCA2 and CDKN1A-interacting protein | chr10 | GO:0006281 | Not Cancer Driver | No | 35 | 0.111 | 99 | 16 | 0.162 | 0 |
BLM | BLM | P54132 | Bloom syndrome protein | chr15 | GO:0006281 | Census | Yes | 153 | 0.108 | 667 | 70 | 0.105 | 8 |
BOD1L1 | BOD1L1 | Q8NFC6 | Biorientation of chromosomes in cell division protein 1-like 1 | chr4 | GO:0006281 | Not Cancer Driver | No | 387 | 0.127 | 3023 | 384 | 0.127 | 0 |
BRIP1 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | GO:0006281 | Census | Yes | 174 | 0.139 | 397 | 59 | 0.149 | 6 |
BTG2 | BTG2 | P78543 | Protein BTG2 | chr1 | GO:0006281 | Census | Yes | 32 | 0.203 | 7 | 2 | 0.286 | 0 |
C19orf57_ENST00000586783 | BRME1 | Q0VDD7 | Break repair meiotic recombinase recruitment factor 1 | chr19 | GO:0006281 | Not Cancer Driver | No | 91 | 0.136 | 632 | 88 | 0.139 | 0 |
CDC14B | CDC14B | O60729 | Dual specificity protein phosphatase CDC14B | chr9 | GO:0006281 | Not Cancer Driver | No | 61 | 0.122 | 138 | 15 | 0.109 | 0 |
CDC5L | CDC5L | Q99459 | Cell division cycle 5-like protein | chr6 | GO:0006281 | Not Cancer Driver | No | 100 | 0.125 | 618 | 77 | 0.125 | 0 |
CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0006281 | Not Cancer Driver | No | 40 | 0.135 | 1 | 0 | 0.0 | 0 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0006281 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
CDK7 | CDK7 | P50613 | Cyclin-dependent kinase 7 | chr5 | GO:0006281 | Not Cancer Driver | No | 41 | 0.118 | 38 | 5 | 0.132 | 0 |
CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | GO:0006281 | Not Cancer Driver | No | 50 | 0.134 | 34 | 2 | 0.059 | 0 |
CENPS | CENPS | Q8N2Z9 | Centromere protein S | chr1 | GO:0006281 | Not Cancer Driver | No | 16 | 0.116 | 65 | 7 | 0.108 | 0 |
CEP164 | CEP164 | Q9UPV0 | Centrosomal protein of 164 kDa | chr11 | GO:0006281 | Not Cancer Driver | No | 161 | 0.11 | 1198 | 124 | 0.104 | 2 |
CGAS | CGAS | Q8N884 | Cyclic GMP-AMP synthase | chr6 | GO:0006281 | Not Cancer Driver | No | 50 | 0.096 | 173 | 7 | 0.04 | 0 |
CHAF1A | CHAF1A | Q13111 | Chromatin assembly factor 1 subunit A | chr19 | GO:0006281 | Not Cancer Driver | No | 133 | 0.139 | 767 | 99 | 0.129 | 0 |
CHAF1B | CHAF1B | Q13112 | Chromatin assembly factor 1 subunit B | chr21 | GO:0006281 | Not Cancer Driver | No | 65 | 0.116 | 186 | 30 | 0.161 | 0 |
CHD1L | CHD1L | Q86WJ1 | Chromodomain-helicase-DNA-binding protein 1-like | chr1 | GO:0006281 | Not Cancer Driver | No | 98 | 0.109 | 225 | 30 | 0.133 | 0 |
CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0006281 | Not Cancer Driver | No | 58 | 0.122 | 86 | 16 | 0.186 | 0 |
CHRNA4 | CHRNA4 | P43681 | Neuronal acetylcholine receptor subunit alpha-4 | chr20 | GO:0006281 | Not Cancer Driver | No | 144 | 0.23 | 186 | 33 | 0.177 | 2 |
CINP | CINP | Q9BW66 | Cyclin-dependent kinase 2-interacting protein | chr14 | GO:0006281 | Not Cancer Driver | No | 22 | 0.104 | 41 | 5 | 0.122 | 0 |
CLSPN | CLSPN | Q9HAW4 | Claspin | chr1 | GO:0006281 | Not Cancer Driver | No | 151 | 0.113 | 1283 | 147 | 0.115 | 0 |
CRY2_ENST00000616080 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0006281 | Not Cancer Driver | No | 72 | 0.121 | 100 | 12 | 0.12 | 0 |
CSNK1E | CSNK1E | P49674 | Casein kinase I isoform epsilon | chr22 | GO:0006281 | Not Cancer Driver | No | 62 | 0.149 | 133 | 18 | 0.135 | 0 |
CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | GO:0006281 | Not Cancer Driver | No | 64 | 0.084 | 102 | 2 | 0.02 | 0 |
CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | GO:0006281 | Not Cancer Driver | No | 138 | 0.151 | 207 | 38 | 0.184 | 2 |
DDB1 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0006281 | Not Cancer Driver | No | 126 | 0.111 | 50 | 8 | 0.16 | 4 |
DDB2 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | GO:0006281 | Census, Compendium | Yes | 45 | 0.105 | 70 | 5 | 0.071 | 2 |
DDX11 | DDX11 | Q96FC9 | ATP-dependent DNA helicase DDX11 | chr12 | GO:0006281 | Not Cancer Driver | No | 154 | 0.159 | 280 | 55 | 0.196 | 1 |
DMAP1_ENST00000315913 | DMAP1 | Q9NPF5 | DNA methyltransferase 1-associated protein 1 | chr1 | GO:0006281 | Not Cancer Driver | No | 49 | 0.105 | 269 | 28 | 0.104 | 0 |
DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0006281 | Not Cancer Driver | No | 120 | 0.113 | 52 | 8 | 0.154 | 3 |
DOT1L | DOT1L | Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | chr19 | GO:0006281 | Compendium | Yes | 178 | 0.116 | 988 | 118 | 0.119 | 0 |
EEPD1 | EEPD1 | Q7L9B9 | Endonuclease/exonuclease/phosphatase family domain-containing protein 1 | chr7 | GO:0006281 | Not Cancer Driver | No | 86 | 0.151 | 249 | 32 | 0.129 | 0 |
EID3 | EID3 | Q8N140 | EP300-interacting inhibitor of differentiation 3 | chr12 | GO:0006281 | Not Cancer Driver | No | 40 | 0.12 | 55 | 6 | 0.109 | 0 |
EMSY_ENST00000529032 | EMSY | Q7Z589 | BRCA2-interacting transcriptional repressor EMSY | chr11 | GO:0006281 | Not Cancer Driver | No | 166 | 0.126 | 1151 | 147 | 0.128 | 0 |
ENDOV | ENDOV | Q8N8Q3 | Endonuclease V | chr17 | GO:0006281 | Not Cancer Driver | No | 28 | 0.099 | 43 | 3 | 0.07 | 0 |
EPC2 | EPC2 | Q52LR7 | Enhancer of polycomb homolog 2 | chr2 | GO:0006281 | Not Cancer Driver | No | 95 | 0.118 | 583 | 67 | 0.115 | 0 |
ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0006281 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
ERCC2 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0006281 | Census, Compendium | Yes | 150 | 0.197 | 5 | 0 | 0.0 | 35 |
ERCC3 | ERCC3 | P19447 | General transcription and DNA repair factor IIH helicase subunit XPB | chr2 | GO:0006281 | Census, Compendium | Yes | 92 | 0.118 | 208 | 22 | 0.106 | 2 |
ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0006281 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
ERCC5 | ERCC5 | P28715 | DNA excision repair protein ERCC-5 | chr13 | GO:0006281 | Census | Yes | 175 | 0.148 | 816 | 121 | 0.148 | 6 |
ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0006281 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
ERCC8 | ERCC8 | Q13216 | DNA excision repair protein ERCC-8 | chr5 | GO:0006281 | Not Cancer Driver | No | 25 | 0.063 | 53 | 8 | 0.151 | 7 |
ETAA1 | ETAA1 | Q9NY74 | Ewing's tumor-associated antigen 1 | chr2 | GO:0006281 | Not Cancer Driver | No | 101 | 0.109 | 735 | 75 | 0.102 | 0 |
EXO1_ENST00000348581 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0006281 | Not Cancer Driver | No | 123 | 0.145 | 472 | 76 | 0.161 | 0 |
EYA2 | EYA2 | O00167 | Eyes absent homolog 2 | chr20 | GO:0006281 | Not Cancer Driver | No | 107 | 0.199 | 204 | 50 | 0.245 | 0 |
EYA4_ENST00000367895 | EYA4 | O95677 | Eyes absent homolog 4 | chr6 | GO:0006281 | Not Cancer Driver | No | 183 | 0.286 | 337 | 108 | 0.32 | 2 |
FAM111A | FAM111A | Q96PZ2 | Serine protease FAM111A | chr11 | GO:0006281 | Not Cancer Driver | No | 78 | 0.128 | 169 | 23 | 0.136 | 5 |
FAN1 | FAN1 | Q9Y2M0 | Fanconi-associated nuclease 1 | chr15 | GO:0006281 | Not Cancer Driver | No | 124 | 0.122 | 212 | 27 | 0.127 | 4 |
FANCA | FANCA | O15360 | Fanconi anemia group A protein | chr16 | GO:0006281 | Census, Compendium | Yes | 160 | 0.11 | 154 | 15 | 0.097 | 27 |
FANCB | FANCB | Q8NB91 | Fanconi anemia group B protein | chrX | GO:0006281 | Not Cancer Driver | No | 109 | 0.127 | 24 | 5 | 0.208 | 0 |
FANCC | FANCC | Q00597 | Fanconi anemia group C protein | chr9 | GO:0006281 | Census, Compendium | Yes | 66 | 0.118 | 13 | 1 | 0.077 | 3 |
FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | GO:0006281 | Census, Compendium | Yes | 176 | 0.121 | 181 | 14 | 0.077 | 3 |
FANCG | FANCG | O15287 | Fanconi anemia group G protein | chr9 | GO:0006281 | Census | Yes | 64 | 0.103 | 48 | 3 | 0.062 | 1 |
FANCL_ENST00000233741 | FANCL | Q9NW38 | E3 ubiquitin-protein ligase FANCL | chr2 | GO:0006281 | Not Cancer Driver | No | 47 | 0.125 | 11 | 0 | 0.0 | 0 |
FANCM | FANCM | Q8IYD8 | Fanconi anemia group M protein | chr14 | GO:0006281 | Not Cancer Driver | No | 268 | 0.131 | 898 | 128 | 0.143 | 0 |
FBXO6 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | GO:0006281 | Not Cancer Driver | No | 31 | 0.106 | 27 | 3 | 0.111 | 0 |
FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0006281 | Census, Compendium | Yes | 322 | 0.455 | 230 | 38 | 0.165 | 0 |
FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0006281 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
FH | FH | P07954 | Fumarate hydratase, mitochondrial | chr1 | GO:0006281 | Census, Compendium | Yes | 67 | 0.131 | 76 | 5 | 0.066 | 13 |
FOXM1_ENST00000359843 | FOXM1 | Q08050 | Forkhead box protein M1 | chr12 | GO:0006281 | Not Cancer Driver | No | 97 | 0.127 | 601 | 73 | 0.121 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | GO:0006281 | Not Cancer Driver | No | 74 | 0.149 | 184 | 30 | 0.163 | 0 |
GADD45A | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0006281 | Not Cancer Driver | No | 10 | 0.061 | 39 | 5 | 0.128 | 0 |
GCNA | GCNA | Q96QF7 | Germ cell nuclear acidic protein | chrX | GO:0006281 | Not Cancer Driver | No | 155 | 0.224 | 513 | 122 | 0.238 | 0 |
GTF2H1_ENST00000453096 | GTF2H1 | P32780 | General transcription factor IIH subunit 1 | chr11 | GO:0006281 | Not Cancer Driver | No | 52 | 0.095 | 139 | 11 | 0.079 | 0 |
GTF2H3 | GTF2H3 | Q13889 | General transcription factor IIH subunit 3 | chr12 | GO:0006281 | Not Cancer Driver | No | 39 | 0.127 | 20 | 1 | 0.05 | 0 |
GTF2H4 | GTF2H4 | Q92759 | General transcription factor IIH subunit 4 | chr6 | GO:0006281 | Not Cancer Driver | No | 46 | 0.1 | 30 | 5 | 0.167 | 0 |
HDAC10 | HDAC10 | Q969S8 | Polyamine deacetylase HDAC10 | chr22 | GO:0006281 | Not Cancer Driver | No | 67 | 0.1 | 121 | 11 | 0.091 | 0 |
HELB | HELB | Q8NG08 | DNA helicase B | chr12 | GO:0006281 | Not Cancer Driver | No | 140 | 0.129 | 300 | 38 | 0.127 | 0 |
HERC2 | HERC2 | O95714 | E3 ubiquitin-protein ligase HERC2 | chr15 | GO:0006281 | Compendium | Yes | 718 | 0.149 | 971 | 150 | 0.154 | 1 |
HINFP | HINFP | Q9BQA5 | Histone H4 transcription factor | chr11 | GO:0006281 | Not Cancer Driver | No | 65 | 0.126 | 154 | 24 | 0.156 | 0 |
HIST3H2A | H2AW | Q7L7L0 | Histone H2A type 3 | chr1 | GO:0006281 | Not Cancer Driver | No | 21 | 0.162 | 61 | 10 | 0.164 | 0 |
HMCES_ENST00000502878 | HMCES | Q96FZ2 | Abasic site processing protein HMCES | chr3 | GO:0006281 | Not Cancer Driver | No | 37 | 0.105 | 131 | 16 | 0.122 | 0 |
HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0006281 | Not Cancer Driver | No | 59 | 0.112 | 335 | 37 | 0.11 | 0 |
HSF2BP | HSF2BP | O75031 | Heat shock factor 2-binding protein | chr21 | GO:0006281 | Not Cancer Driver | No | 52 | 0.156 | 23 | 3 | 0.13 | 1 |
HUS1 | HUS1 | O60921 | Checkpoint protein HUS1 | chr7 | GO:0006281 | Not Cancer Driver | No | 25 | 0.089 | 17 | 2 | 0.118 | 0 |
IGHMBP2 | IGHMBP2 | P38935 | DNA-binding protein SMUBP-2 | chr11 | GO:0006281 | Not Cancer Driver | No | 136 | 0.137 | 354 | 53 | 0.15 | 31 |
INIP | INIP | Q9NRY2 | SOSS complex subunit C | chr9 | GO:0006281 | Not Cancer Driver | No | 25 | 0.24 | 79 | 16 | 0.203 | 0 |
INO80B | INO80B | Q9C086 | INO80 complex subunit B | chr2 | GO:0006281 | Not Cancer Driver | No | 35 | 0.098 | 336 | 33 | 0.098 | 0 |
INO80C_ENST00000334598 | INO80C | Q6PI98 | INO80 complex subunit C | chr18 | GO:0006281 | Not Cancer Driver | No | 18 | 0.094 | 109 | 11 | 0.101 | 0 |
INO80D | INO80D | Q53TQ3 | INO80 complex subunit D | chr2 | GO:0006281 | Not Cancer Driver | No | 110 | 0.107 | 738 | 93 | 0.126 | 0 |
INO80E | INO80E | Q8NBZ0 | INO80 complex subunit E | chr16 | GO:0006281 | Not Cancer Driver | No | 21 | 0.086 | 210 | 21 | 0.1 | 0 |
INO80_ENST00000401393 | INO80 | Q9ULG1 | Chromatin-remodeling ATPase INO80 | chr15 | GO:0006281 | Compendium | Yes | 173 | 0.111 | 682 | 76 | 0.111 | 0 |
INTS3_ENST00000435409 | INTS3 | Q68E01 | Integrator complex subunit 3 | chr1 | GO:0006281 | Not Cancer Driver | No | 125 | 0.12 | 213 | 25 | 0.117 | 0 |
JMY | JMY | Q8N9B5 | Junction-mediating and -regulatory protein | chr5 | GO:0006281 | Not Cancer Driver | No | 88 | 0.089 | 572 | 52 | 0.091 | 0 |
KAT7 | KAT7 | O95251 | Histone acetyltransferase KAT7 | chr17 | GO:0006281 | Census | Yes | 97 | 0.159 | 327 | 47 | 0.144 | 0 |
KIF22 | KIF22 | Q14807 | Kinesin-like protein KIF22 | chr16 | GO:0006281 | Not Cancer Driver | No | 79 | 0.119 | 322 | 35 | 0.109 | 4 |
KIN | KIN | O60870 | DNA/RNA-binding protein KIN17 | chr10 | GO:0006281 | Not Cancer Driver | No | 52 | 0.132 | 137 | 13 | 0.095 | 0 |
KMT5B_ENST00000615954 | KMT5B | Q4FZB7 | Histone-lysine N-methyltransferase KMT5B | chr11 | GO:0006281 | Not Cancer Driver | No | 147 | 0.166 | 659 | 113 | 0.171 | 0 |
KMT5C | KMT5C | Q86Y97 | Histone-lysine N-methyltransferase KMT5C | chr19 | GO:0006281 | Not Cancer Driver | No | 37 | 0.08 | 142 | 9 | 0.063 | 0 |
LIG1 | LIG1 | P18858 | DNA ligase 1 | chr19 | GO:0006281 | Not Cancer Driver | No | 137 | 0.149 | 397 | 62 | 0.156 | 0 |
LIG3 | LIG3 | P49916 | DNA ligase 3 | chr17 | GO:0006281 | Not Cancer Driver | No | 125 | 0.124 | 280 | 36 | 0.129 | 0 |
LIG4 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0006281 | Not Cancer Driver | No | 134 | 0.147 | 63 | 10 | 0.159 | 2 |
MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:0006281 | Not Cancer Driver | No | 22 | 0.104 | 0 | 0 | 0.0 | 1 |
MBD4 | MBD4 | O95243 | Methyl-CpG-binding domain protein 4 | chr3 | GO:0006281 | Not Cancer Driver | No | 61 | 0.105 | 268 | 27 | 0.101 | 0 |
MC1R_ENST00000639847 | MC1R | Q01726 | Melanocyte-stimulating hormone receptor | chr16 | GO:0006281 | Not Cancer Driver | No | 39 | 0.123 | 0 | 0 | 0.0 | 5 |
MCM8_ENST00000378896 | MCM8 | Q9UJA3 | DNA helicase MCM8 | chr20 | GO:0006281 | Not Cancer Driver | No | 94 | 0.112 | 188 | 19 | 0.101 | 1 |
MCM9_ENST00000619706 | MCM9 | Q9NXL9 | DNA helicase MCM9 | chr6 | GO:0006281 | Not Cancer Driver | No | 56 | 0.049 | 523 | 13 | 0.025 | 0 |
MCRS1_ENST00000550165 | MCRS1 | Q96EZ8 | Microspherule protein 1 | chr12 | GO:0006281 | Not Cancer Driver | No | 72 | 0.156 | 151 | 18 | 0.119 | 0 |
MDC1 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | GO:0006281 | Not Cancer Driver | No | 249 | 0.119 | 1829 | 223 | 0.122 | 0 |
MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0006281 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
MGME1 | MGME1 | Q9BQP7 | Mitochondrial genome maintenance exonuclease 1 | chr20 | GO:0006281 | Not Cancer Driver | No | 33 | 0.096 | 95 | 7 | 0.074 | 1 |
MMS19 | MMS19 | Q96T76 | MMS19 nucleotide excision repair protein homolog | chr10 | GO:0006281 | Not Cancer Driver | No | 73 | 0.071 | 11 | 0 | 0.0 | 0 |
MNAT1 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:0006281 | Not Cancer Driver | No | 23 | 0.074 | 64 | 2 | 0.031 | 0 |
MORF4L2_ENST00000433176 | MORF4L2 | Q15014 | Mortality factor 4-like protein 2 | chrX | GO:0006281 | Not Cancer Driver | No | 44 | 0.153 | 136 | 21 | 0.154 | 0 |
MRE11 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0006281 | Not Cancer Driver | No | 84 | 0.119 | 292 | 35 | 0.12 | 1 |
MRNIP | MRNIP | Q6NTE8 | MRN complex-interacting protein | chr5 | GO:0006281 | Not Cancer Driver | No | 44 | 0.128 | 268 | 35 | 0.131 | 0 |
MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0006281 | Census | Yes | 92 | 0.099 | 37 | 4 | 0.108 | 70 |
MSH3 | MSH3 | P20585 | DNA mismatch repair protein Msh3 | chr5 | GO:0006281 | Not Cancer Driver | No | 100 | 0.088 | 211 | 20 | 0.095 | 0 |
MSH6 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | GO:0006281 | Census | Yes | 154 | 0.113 | 386 | 41 | 0.106 | 6 |
MUS81 | MUS81 | Q96NY9 | Crossover junction endonuclease MUS81 | chr11 | GO:0006281 | Not Cancer Driver | No | 67 | 0.122 | 232 | 38 | 0.164 | 0 |
MUTYH | MUTYH | Q9UIF7 | Adenine DNA glycosylase | chr1 | GO:0006281 | Census | Yes | 90 | 0.165 | 198 | 29 | 0.146 | 23 |
NABP1 | NABP1 | Q96AH0 | SOSS complex subunit B2 | chr2 | GO:0006281 | Not Cancer Driver | No | 25 | 0.123 | 102 | 11 | 0.108 | 0 |
NABP2_ENST00000341463 | NABP2 | Q9BQ15 | SOSS complex subunit B1 | chr12 | GO:0006281 | Not Cancer Driver | No | 25 | 0.118 | 125 | 17 | 0.136 | 0 |
NFRKB_ENST00000446488 | NFRKB | Q6P4R8 | Nuclear factor related to kappa-B-binding protein | chr11 | GO:0006281 | Not Cancer Driver | No | 128 | 0.099 | 838 | 74 | 0.088 | 0 |
NIPBL | NIPBL | Q6KC79 | Nipped-B-like protein | chr5 | GO:0006281 | Compendium | Yes | 353 | 0.126 | 1528 | 184 | 0.12 | 37 |
NONO | NONO | Q15233 | Non-POU domain-containing octamer-binding protein | chrX | GO:0006281 | Census, Compendium | Yes | 101 | 0.214 | 349 | 64 | 0.183 | 0 |
NOP53 | NOP53 | Q9NZM5 | Ribosome biogenesis protein NOP53 | chr19 | GO:0006281 | Not Cancer Driver | No | 59 | 0.123 | 391 | 41 | 0.105 | 0 |
NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | GO:0006281 | Census, Compendium | Yes | 29 | 0.099 | 249 | 22 | 0.088 | 0 |
NSMCE3 | NSMCE3 | Q96MG7 | Non-structural maintenance of chromosomes element 3 homolog | chr15 | GO:0006281 | Not Cancer Driver | No | 33 | 0.109 | 128 | 7 | 0.055 | 2 |
NSMCE4A | NSMCE4A | Q9NXX6 | Non-structural maintenance of chromosomes element 4 homolog A | chr10 | GO:0006281 | Not Cancer Driver | No | 17 | 0.044 | 200 | 5 | 0.025 | 0 |
NUDT1_ENST00000397046 | NUDT1 | P36639 | Oxidized purine nucleoside triphosphate hydrolase | chr7 | GO:0006281 | Not Cancer Driver | No | 25 | 0.16 | 17 | 4 | 0.235 | 0 |
OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | GO:0006281 | Not Cancer Driver | No | 31 | 0.114 | 33 | 2 | 0.061 | 0 |
PAGR1 | PAGR1 | Q9BTK6 | PAXIP1-associated glutamate-rich protein 1 | chr16 | GO:0006281 | Not Cancer Driver | No | 16 | 0.063 | 254 | 16 | 0.063 | 0 |
PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0006281 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0006281 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
PARP2 | PARP2 | Q9UGN5 | Poly [ADP-ribose] polymerase 2 | chr14 | GO:0006281 | Not Cancer Driver | No | 74 | 0.127 | 172 | 23 | 0.134 | 0 |
PARP3_ENST00000431474 | PARP3 | Q9Y6F1 | Protein mono-ADP-ribosyltransferase PARP3 | chr3 | GO:0006281 | Not Cancer Driver | No | 70 | 0.131 | 269 | 38 | 0.141 | 0 |
PARP4 | PARP4 | Q9UKK3 | Protein mono-ADP-ribosyltransferase PARP4 | chr13 | GO:0006281 | Compendium | Yes | 218 | 0.126 | 325 | 40 | 0.123 | 0 |
PARPBP_ENST00000327680 | PARPBP | Q9NWS1 | PCNA-interacting partner | chr12 | GO:0006281 | Not Cancer Driver | No | 70 | 0.121 | 174 | 26 | 0.149 | 0 |
PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | GO:0006281 | Not Cancer Driver | No | 120 | 0.112 | 461 | 39 | 0.085 | 0 |
PDS5A | PDS5A | Q29RF7 | Sister chromatid cohesion protein PDS5 homolog A | chr4 | GO:0006281 | Not Cancer Driver | No | 150 | 0.112 | 295 | 34 | 0.115 | 0 |
PDS5B | PDS5B | Q9NTI5 | Sister chromatid cohesion protein PDS5 homolog B | chr13 | GO:0006281 | Not Cancer Driver | No | 174 | 0.12 | 455 | 61 | 0.134 | 0 |
PIF1_ENST00000559239 | PIF1 | Q9H611 | ATP-dependent DNA helicase PIF1 | chr15 | GO:0006281 | Not Cancer Driver | No | 54 | 0.084 | 209 | 11 | 0.053 | 0 |
PNKP | PNKP | Q96T60 | Bifunctional polynucleotide phosphatase/kinase | chr19 | GO:0006281 | Not Cancer Driver | No | 53 | 0.102 | 177 | 23 | 0.13 | 4 |
POLA1_ENST00000379059 | POLA1 | P09884 | DNA polymerase alpha catalytic subunit | chrX | GO:0006281 | Not Cancer Driver | No | 185 | 0.127 | 347 | 45 | 0.13 | 3 |
POLB | POLB | P06746 | DNA polymerase beta | chr8 | GO:0006281 | Not Cancer Driver | No | 43 | 0.128 | 87 | 11 | 0.126 | 0 |
POLD1_ENST00000440232 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | GO:0006281 | Census, Compendium | Yes | 179 | 0.162 | 214 | 31 | 0.145 | 2 |
POLD2_ENST00000452185 | POLD2 | P49005 | DNA polymerase delta subunit 2 | chr7 | GO:0006281 | Not Cancer Driver | No | 49 | 0.104 | 65 | 3 | 0.046 | 0 |
POLD3 | POLD3 | Q15054 | DNA polymerase delta subunit 3 | chr11 | GO:0006281 | Not Cancer Driver | No | 51 | 0.109 | 326 | 39 | 0.12 | 0 |
POLDIP2 | POLDIP2 | Q9Y2S7 | Polymerase delta-interacting protein 2 | chr17 | GO:0006281 | Not Cancer Driver | No | 36 | 0.098 | 94 | 13 | 0.138 | 0 |
POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | GO:0006281 | Census, Compendium | Yes | 409 | 0.179 | 239 | 44 | 0.184 | 3 |
POLE2 | POLE2 | P56282 | DNA polymerase epsilon subunit 2 | chr14 | GO:0006281 | Not Cancer Driver | No | 53 | 0.101 | 32 | 2 | 0.062 | 0 |
POLG2 | POLG2 | Q9UHN1 | DNA polymerase subunit gamma-2, mitochondrial | chr17 | GO:0006281 | Not Cancer Driver | No | 64 | 0.132 | 46 | 4 | 0.087 | 3 |
POLH | POLH | Q9Y253 | DNA polymerase eta | chr6 | GO:0006281 | Not Cancer Driver | No | 72 | 0.101 | 291 | 20 | 0.069 | 10 |
POLI | POLI | Q9UNA4 | DNA polymerase iota | chr18 | GO:0006281 | Not Cancer Driver | No | 82 | 0.111 | 300 | 32 | 0.107 | 0 |
POLK | POLK | Q9UBT6 | DNA polymerase kappa | chr5 | GO:0006281 | Not Cancer Driver | No | 97 | 0.111 | 293 | 36 | 0.123 | 0 |
POLQ | POLQ | O75417 | DNA polymerase theta | chr3 | GO:0006281 | Census, Compendium | Yes | 364 | 0.141 | 949 | 135 | 0.142 | 0 |
POLR2I | POLR2I | P36954 | DNA-directed RNA polymerase II subunit RPB9 | chr19 | GO:0006281 | Not Cancer Driver | No | 21 | 0.168 | 22 | 5 | 0.227 | 0 |
PRDM9 | PRDM9 | Q9NQV7 | Histone-lysine N-methyltransferase PRDM9 | chr5 | GO:0006281 | Not Cancer Driver | No | 494 | 0.553 | 372 | 201 | 0.54 | 0 |
PRIMPOL_ENST00000503752 | PRIMPOL | Q96LW4 | DNA-directed primase/polymerase protein | chr4 | GO:0006281 | Not Cancer Driver | No | 50 | 0.089 | 92 | 7 | 0.076 | 0 |
PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0006281 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
PSME4 | PSME4 | Q14997 | Proteasome activator complex subunit 4 | chr2 | GO:0006281 | Not Cancer Driver | No | 214 | 0.116 | 134 | 12 | 0.09 | 0 |
PTTG1_ENST00000520452 | PTTG1 | O95997 | Securin | chr5 | GO:0006281 | Not Cancer Driver | No | 17 | 0.084 | 141 | 6 | 0.043 | 0 |
PWWP3A | PWWP3A | Q2TAK8 | PWWP domain-containing DNA repair factor 3A | chr19 | GO:0006281 | Not Cancer Driver | No | 77 | 0.108 | 352 | 39 | 0.111 | 0 |
RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0006281 | Not Cancer Driver | No | 29 | 0.103 | 4 | 1 | 0.25 | 0 |
RAD17 | RAD17 | O75943 | Cell cycle checkpoint protein RAD17 | chr5 | GO:0006281 | Census | Yes | 78 | 0.115 | 207 | 19 | 0.092 | 0 |
RAD18 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | GO:0006281 | Not Cancer Driver | No | 59 | 0.119 | 328 | 43 | 0.131 | 0 |
RAD21 | RAD21 | O60216 | Double-strand-break repair protein rad21 homolog | chr8 | GO:0006281 | Census, Compendium | Yes | 115 | 0.182 | 421 | 74 | 0.176 | 3 |
RAD21L1 | RAD21L1 | Q9H4I0 | Double-strand-break repair protein rad21-like protein 1 | chr20 | GO:0006281 | Not Cancer Driver | No | 37 | 0.067 | 186 | 5 | 0.027 | 0 |
RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0006281 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
RAD51AP1 | RAD51AP1 | Q96B01 | RAD51-associated protein 1 | chr12 | GO:0006281 | Not Cancer Driver | No | 46 | 0.131 | 335 | 43 | 0.128 | 0 |
RAD51B_ENST00000487270 | RAD51B | O15315 | DNA repair protein RAD51 homolog 2 | chr14 | GO:0006281 | Census | Yes | 45 | 0.117 | 13 | 0 | 0.0 | 0 |
RAD51C | RAD51C | O43502 | DNA repair protein RAD51 homolog 3 | chr17 | GO:0006281 | Not Cancer Driver | No | 47 | 0.125 | 18 | 2 | 0.111 | 6 |
RAD51D_ENST00000394589 | RAD51D | O75771 | DNA repair protein RAD51 homolog 4 | chr17 | GO:0006281 | Not Cancer Driver | No | 34 | 0.104 | 49 | 10 | 0.204 | 0 |
RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0006281 | Not Cancer Driver | No | 42 | 0.124 | 47 | 5 | 0.106 | 3 |
RAD52 | RAD52 | P43351 | DNA repair protein RAD52 homolog | chr12 | GO:0006281 | Not Cancer Driver | No | 41 | 0.098 | 251 | 30 | 0.12 | 0 |
RAD54L_ENST00000442598 | RAD54L | Q92698 | DNA repair and recombination protein RAD54-like | chr1 | GO:0006281 | Not Cancer Driver | No | 79 | 0.106 | 124 | 13 | 0.105 | 0 |
RAD9A | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:0006281 | Not Cancer Driver | No | 34 | 0.087 | 135 | 7 | 0.052 | 0 |
RAD9B | RAD9B | Q6WBX8 | Cell cycle checkpoint control protein RAD9B | chr12 | GO:0006281 | Not Cancer Driver | No | 46 | 0.108 | 40 | 6 | 0.15 | 0 |
RBBP8_ENST00000327155 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:0006281 | Not Cancer Driver | No | 99 | 0.11 | 750 | 76 | 0.101 | 1 |
RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0006281 | Not Cancer Driver | No | 10 | 0.093 | 18 | 1 | 0.056 | 0 |
RCHY1 | RCHY1 | Q96PM5 | RING finger and CHY zinc finger domain-containing protein 1 | chr4 | GO:0006281 | Not Cancer Driver | No | 33 | 0.126 | 23 | 0 | 0.0 | 0 |
REC8_ENST00000611366 | REC8 | O95072 | Meiotic recombination protein REC8 homolog | chr14 | GO:0006281 | Not Cancer Driver | No | 60 | 0.11 | 244 | 26 | 0.107 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | GO:0006281 | Census, Compendium | Yes | 138 | 0.114 | 608 | 71 | 0.117 | 1 |
RECQL5 | RECQL5 | O94762 | ATP-dependent DNA helicase Q5 | chr17 | GO:0006281 | Not Cancer Driver | No | 132 | 0.133 | 495 | 71 | 0.143 | 0 |
RECQL_ENST00000421138 | RECQL | P46063 | ATP-dependent DNA helicase Q1 | chr12 | GO:0006281 | Not Cancer Driver | No | 67 | 0.103 | 91 | 5 | 0.055 | 0 |
REV1 | REV1 | Q9UBZ9 | DNA repair protein REV1 | chr2 | GO:0006281 | Not Cancer Driver | No | 122 | 0.098 | 660 | 67 | 0.102 | 0 |
REV3L_ENST00000368802 | REV3L | O60673 | DNA polymerase zeta catalytic subunit | chr6 | GO:0006281 | Not Cancer Driver | No | 379 | 0.121 | 1665 | 211 | 0.127 | 0 |
REXO4 | REXO4 | Q9GZR2 | RNA exonuclease 4 | chr9 | GO:0006281 | Not Cancer Driver | No | 34 | 0.081 | 298 | 26 | 0.087 | 0 |
RFC1 | RFC1 | P35251 | Replication factor C subunit 1 | chr4 | GO:0006281 | Not Cancer Driver | No | 147 | 0.128 | 674 | 82 | 0.122 | 0 |
RFC2 | RFC2 | P35250 | Replication factor C subunit 2 | chr7 | GO:0006281 | Not Cancer Driver | No | 45 | 0.127 | 39 | 6 | 0.154 | 0 |
RFC3 | RFC3 | P40938 | Replication factor C subunit 3 | chr13 | GO:0006281 | Not Cancer Driver | No | 31 | 0.087 | 13 | 1 | 0.077 | 0 |
RFC4_ENST00000296273 | RFC4 | P35249 | Replication factor C subunit 4 | chr3 | GO:0006281 | Not Cancer Driver | No | 58 | 0.16 | 50 | 8 | 0.16 | 0 |
RFC5 | RFC5 | P40937 | Replication factor C subunit 5 | chr12 | GO:0006281 | Not Cancer Driver | No | 38 | 0.112 | 20 | 1 | 0.05 | 0 |
RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | GO:0006281 | Not Cancer Driver | No | 287 | 0.116 | 1355 | 164 | 0.121 | 0 |
RMI2 | RMI2 | Q96E14 | RecQ-mediated genome instability protein 2 | chr16 | GO:0006281 | Census | Yes | 12 | 0.082 | 86 | 5 | 0.058 | 0 |
RNF111_ENST00000557998 | RNF111 | Q6ZNA4 | E3 ubiquitin-protein ligase Arkadia | chr15 | GO:0006281 | Not Cancer Driver | No | 111 | 0.112 | 855 | 96 | 0.112 | 0 |
RNF113A | RNF113A | O15541 | E3 ubiquitin-protein ligase RNF113A | chrX | GO:0006281 | Not Cancer Driver | No | 61 | 0.178 | 226 | 51 | 0.226 | 0 |
RPA1 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | GO:0006281 | Not Cancer Driver | No | 51 | 0.083 | 98 | 6 | 0.061 | 0 |
RPA3 | RPA3 | P35244 | Replication protein A 14 kDa subunit | chr7 | GO:0006281 | Not Cancer Driver | No | 13 | 0.107 | 4 | 1 | 0.25 | 0 |
RPA4 | RPA4 | Q13156 | Replication protein A 30 kDa subunit | chrX | GO:0006281 | Not Cancer Driver | No | 66 | 0.253 | 58 | 15 | 0.259 | 0 |
RPAIN_ENST00000381209 | RPAIN | Q86UA6 | RPA-interacting protein | chr17 | GO:0006281 | Not Cancer Driver | No | 31 | 0.142 | 31 | 5 | 0.161 | 0 |
RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0006281 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
RRM1 | RRM1 | P23921 | Ribonucleoside-diphosphate reductase large subunit | chr11 | GO:0006281 | Not Cancer Driver | No | 74 | 0.093 | 41 | 7 | 0.171 | 0 |
RRM2B | RRM2B | Q7LG56 | Ribonucleoside-diphosphate reductase subunit M2 B | chr8 | GO:0006281 | Not Cancer Driver | No | 46 | 0.131 | 32 | 5 | 0.156 | 9 |
RTEL1_ENST00000370018 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:0006281 | Not Cancer Driver | No | 144 | 0.118 | 474 | 64 | 0.135 | 14 |
RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | GO:0006281 | Not Cancer Driver | No | 54 | 0.118 | 67 | 7 | 0.104 | 0 |
RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0006281 | Not Cancer Driver | No | 62 | 0.134 | 100 | 13 | 0.13 | 0 |
SHLD1 | SHLD1 | Q8IYI0 | Shieldin complex subunit 1 | chr20 | GO:0006281 | Not Cancer Driver | No | 30 | 0.146 | 116 | 20 | 0.172 | 0 |
SHLD2_ENST00000298784 | SHLD2 | Q86V20 | Shieldin complex subunit 2 | chr10 | GO:0006281 | Not Cancer Driver | No | 84 | 0.101 | 157 | 14 | 0.089 | 0 |
SHLD3 | SHLD3 | Q6ZNX1 | Shieldin complex subunit 3 | chr5 | GO:0006281 | Not Cancer Driver | No | 3 | 0.012 | 81 | 1 | 0.012 | 0 |
SHPRH | SHPRH | Q149N8 | E3 ubiquitin-protein ligase SHPRH | chr6 | GO:0006281 | Not Cancer Driver | No | 227 | 0.135 | 359 | 51 | 0.142 | 0 |
SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0006281 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | GO:0006281 | Not Cancer Driver | No | 48 | 0.12 | 163 | 15 | 0.092 | 0 |
SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | GO:0006281 | Not Cancer Driver | No | 3 | 0.011 | 80 | 1 | 0.013 | 0 |
SLX4 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | GO:0006281 | Not Cancer Driver | No | 271 | 0.148 | 1573 | 232 | 0.147 | 0 |
SMARCAL1 | SMARCAL1 | Q9NZC9 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 | chr2 | GO:0006281 | Not Cancer Driver | No | 128 | 0.134 | 335 | 49 | 0.146 | 11 |
SMC1A | SMC1A | Q14683 | Structural maintenance of chromosomes protein 1A | chrX | GO:0006281 | Census, Compendium | Yes | 200 | 0.162 | 717 | 114 | 0.159 | 21 |
SMC3 | SMC3 | Q9UQE7 | Structural maintenance of chromosomes protein 3 | chr10 | GO:0006281 | Not Cancer Driver | No | 149 | 0.122 | 605 | 70 | 0.116 | 0 |
SMG1 | SMG1 | Q96Q15 | Serine/threonine-protein kinase SMG1 | chr16 | GO:0006281 | Not Cancer Driver | No | 348 | 0.095 | 605 | 73 | 0.121 | 0 |
SPO11 | SPO11 | Q9Y5K1 | Meiotic recombination protein SPO11 | chr20 | GO:0006281 | Not Cancer Driver | No | 59 | 0.149 | 26 | 5 | 0.192 | 0 |
SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | GO:0006281 | Not Cancer Driver | No | 73 | 0.149 | 252 | 38 | 0.151 | 1 |
SSRP1 | SSRP1 | Q08945 | FACT complex subunit SSRP1 | chr11 | GO:0006281 | Not Cancer Driver | No | 92 | 0.13 | 308 | 35 | 0.114 | 0 |
STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0006281 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | GO:0006281 | Not Cancer Driver | No | 10 | 0.099 | 76 | 7 | 0.092 | 0 |
SUPT16H | SUPT16H | Q9Y5B9 | FACT complex subunit SPT16 | chr14 | GO:0006281 | Not Cancer Driver | No | 147 | 0.14 | 301 | 44 | 0.146 | 0 |
TAOK1 | TAOK1 | Q7L7X3 | Serine/threonine-protein kinase TAO1 | chr17 | GO:0006281 | Not Cancer Driver | No | 116 | 0.116 | 601 | 59 | 0.098 | 0 |
TAOK3 | TAOK3 | Q9H2K8 | Serine/threonine-protein kinase TAO3 | chr12 | GO:0006281 | Not Cancer Driver | No | 123 | 0.137 | 494 | 64 | 0.13 | 0 |
TDP1_ENST00000393454 | TDP1 | Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | chr14 | GO:0006281 | Not Cancer Driver | No | 81 | 0.133 | 179 | 25 | 0.14 | 1 |
TEX15_ENST00000256246 | TEX15 | Q9BXT5 | Testis-expressed protein 15 | chr8 | GO:0006281 | Not Cancer Driver | No | 479 | 0.172 | 1258 | 223 | 0.177 | 0 |
TEX264_ENST00000416589 | TEX264 | Q9Y6I9 | Testis-expressed protein 264 | chr3 | GO:0006281 | Not Cancer Driver | No | 40 | 0.128 | 107 | 11 | 0.103 | 0 |
TFPT | TFPT | P0C1Z6 | TCF3 fusion partner | chr19 | GO:0006281 | Census | Yes | 41 | 0.162 | 237 | 41 | 0.173 | 0 |
TICRR | TICRR | Q7Z2Z1 | Treslin | chr15 | GO:0006281 | Not Cancer Driver | No | 201 | 0.105 | 1308 | 129 | 0.099 | 0 |
TIMELESS | TIMELESS | Q9UNS1 | Protein timeless homolog | chr12 | GO:0006281 | Not Cancer Driver | No | 154 | 0.127 | 367 | 51 | 0.139 | 0 |
TNP1 | TNP1 | P09430 | Spermatid nuclear transition protein 1 | chr2 | GO:0006281 | Not Cancer Driver | No | 21 | 0.382 | 55 | 21 | 0.382 | 0 |
TOPBP1 | TOPBP1 | Q92547 | DNA topoisomerase 2-binding protein 1 | chr3 | GO:0006281 | Not Cancer Driver | No | 169 | 0.111 | 577 | 59 | 0.102 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0006281 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
TRAIP | TRAIP | Q9BWF2 | E3 ubiquitin-protein ligase TRAIP | chr3 | GO:0006281 | Not Cancer Driver | No | 63 | 0.134 | 240 | 33 | 0.138 | 1 |
TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0006281 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
TREX2_ENST00000370231 | TREX2 | Q9BQ50 | Three prime repair exonuclease 2 | chrX | GO:0006281 | Not Cancer Driver | No | 33 | 0.14 | 23 | 6 | 0.261 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | GO:0006281 | Not Cancer Driver | No | 87 | 0.104 | 430 | 41 | 0.095 | 0 |
TRIP12_ENST00000283943 | TRIP12 | Q14669 | E3 ubiquitin-protein ligase TRIP12 | chr2 | GO:0006281 | Not Cancer Driver | No | 224 | 0.112 | 845 | 117 | 0.138 | 4 |
TRRAP | TRRAP | Q9Y4A5 | Transformation/transcription domain-associated protein | chr7 | GO:0006281 | Census, Compendium | Yes | 554 | 0.144 | 402 | 59 | 0.147 | 8 |
TTC5 | TTC5 | Q8N0Z6 | Tetratricopeptide repeat protein 5 | chr14 | GO:0006281 | Not Cancer Driver | No | 65 | 0.148 | 151 | 19 | 0.126 | 0 |
UBE2A | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | GO:0006281 | Compendium | Yes | 35 | 0.23 | 67 | 13 | 0.194 | 2 |
UBE2B | UBE2B | P63146 | Ubiquitin-conjugating enzyme E2 B | chr5 | GO:0006281 | Not Cancer Driver | No | 13 | 0.086 | 68 | 6 | 0.088 | 0 |
UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | GO:0006281 | Not Cancer Driver | No | 21 | 0.143 | 13 | 4 | 0.308 | 0 |
UBE2T | UBE2T | Q9NPD8 | Ubiquitin-conjugating enzyme E2 T | chr1 | GO:0006281 | Not Cancer Driver | No | 12 | 0.061 | 97 | 9 | 0.093 | 1 |
UBE2U_ENST00000611228 | UBE2U | Q5VVX9 | Ubiquitin-conjugating enzyme E2 U | chr1 | GO:0006281 | Not Cancer Driver | No | 38 | 0.118 | 66 | 1 | 0.015 | 0 |
UBE2V2 | UBE2V2 | Q15819 | Ubiquitin-conjugating enzyme E2 variant 2 | chr8 | GO:0006281 | Not Cancer Driver | No | 22 | 0.152 | 76 | 12 | 0.158 | 0 |
UBE2W_ENST00000602593 | UBE2W | Q96B02 | Ubiquitin-conjugating enzyme E2 W | chr8 | GO:0006281 | Not Cancer Driver | No | 19 | 0.126 | 26 | 5 | 0.192 | 0 |
UBQLN4 | UBQLN4 | Q9NRR5 | Ubiquilin-4 | chr1 | GO:0006281 | Not Cancer Driver | No | 70 | 0.116 | 561 | 67 | 0.119 | 1 |
UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | GO:0006281 | Census, Compendium | Yes | 340 | 0.121 | 1296 | 162 | 0.125 | 0 |
UCHL5 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | GO:0006281 | Not Cancer Driver | No | 33 | 0.1 | 41 | 7 | 0.171 | 0 |
UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0006281 | Not Cancer Driver | No | 109 | 0.137 | 141 | 24 | 0.17 | 0 |
UHRF1_ENST00000616255 | UHRF1 | Q96T88 | E3 ubiquitin-protein ligase UHRF1 | chr19 | GO:0006281 | Not Cancer Driver | No | 97 | 0.122 | 353 | 49 | 0.139 | 0 |
UNG | UNG | P13051 | Uracil-DNA glycosylase | chr12 | GO:0006281 | Not Cancer Driver | No | 34 | 0.109 | 96 | 13 | 0.135 | 1 |
UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0006281 | Not Cancer Driver | No | 146 | 0.129 | 329 | 36 | 0.109 | 0 |
USP1_ENST00000371146 | USP1 | O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | chr1 | GO:0006281 | Not Cancer Driver | No | 63 | 0.08 | 403 | 30 | 0.074 | 0 |
USP28 | USP28 | Q96RU2 | Ubiquitin carboxyl-terminal hydrolase 28 | chr11 | GO:0006281 | Not Cancer Driver | No | 151 | 0.14 | 311 | 25 | 0.08 | 0 |
USP3 | USP3 | Q9Y6I4 | Ubiquitin carboxyl-terminal hydrolase 3 | chr15 | GO:0006281 | Not Cancer Driver | No | 60 | 0.115 | 45 | 4 | 0.089 | 0 |
USP45 | USP45 | Q70EL2 | Ubiquitin carboxyl-terminal hydrolase 45 | chr6 | GO:0006281 | Not Cancer Driver | No | 96 | 0.118 | 275 | 28 | 0.102 | 0 |
USP51 | USP51 | Q70EK9 | Ubiquitin carboxyl-terminal hydrolase 51 | chrX | GO:0006281 | Not Cancer Driver | No | 100 | 0.141 | 246 | 34 | 0.138 | 0 |
USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | GO:0006281 | Not Cancer Driver | No | 170 | 0.154 | 215 | 45 | 0.209 | 0 |
UVRAG | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0006281 | Not Cancer Driver | No | 89 | 0.127 | 243 | 28 | 0.115 | 0 |
UVSSA | UVSSA | Q2YD98 | UV-stimulated scaffold protein A | chr4 | GO:0006281 | Not Cancer Driver | No | 101 | 0.142 | 519 | 70 | 0.135 | 1 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0006281 | Not Cancer Driver | No | 88 | 0.109 | 186 | 16 | 0.086 | 16 |
VCPIP1 | VCPIP1 | Q96JH7 | Deubiquitinating protein VCPIP1 | chr8 | GO:0006281 | Not Cancer Driver | No | 133 | 0.109 | 543 | 61 | 0.112 | 0 |
WDHD1 | WDHD1 | O75717 | WD repeat and HMG-box DNA-binding protein 1 | chr14 | GO:0006281 | Not Cancer Driver | No | 100 | 0.089 | 474 | 31 | 0.065 | 0 |
WRAP53 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:0006281 | Not Cancer Driver | No | 66 | 0.12 | 232 | 29 | 0.125 | 4 |
WRN | WRN | Q14191 | Werner syndrome ATP-dependent helicase | chr8 | GO:0006281 | Census, Compendium | Yes | 164 | 0.115 | 373 | 41 | 0.11 | 2 |
XAB2 | XAB2 | Q9HCS7 | Pre-mRNA-splicing factor SYF1 | chr19 | GO:0006281 | Not Cancer Driver | No | 128 | 0.15 | 127 | 17 | 0.134 | 0 |
XPA | XPA | P23025 | DNA repair protein complementing XP-A cells | chr9 | GO:0006281 | Census | Yes | 27 | 0.099 | 121 | 13 | 0.107 | 5 |
XPC | XPC | Q01831 | DNA repair protein complementing XP-C cells | chr3 | GO:0006281 | Census, Compendium | Yes | 88 | 0.094 | 479 | 48 | 0.1 | 2 |
XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0006281 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
XRCC2 | XRCC2 | O43543 | DNA repair protein XRCC2 | chr7 | GO:0006281 | Not Cancer Driver | No | 36 | 0.129 | 9 | 1 | 0.111 | 2 |
XRCC3_ENST00000352127 | XRCC3 | O43542 | DNA repair protein XRCC3 | chr14 | GO:0006281 | Not Cancer Driver | No | 24 | 0.069 | 35 | 2 | 0.057 | 1 |
XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0006281 | Not Cancer Driver | No | 66 | 0.108 | 140 | 12 | 0.086 | 0 |
ZBTB1 | ZBTB1 | Q9Y2K1 | Zinc finger and BTB domain-containing protein 1 | chr14 | GO:0006281 | Not Cancer Driver | No | 70 | 0.098 | 271 | 27 | 0.1 | 0 |
ZBTB7A_ENST00000601588 | ZBTB7A | O95365 | Zinc finger and BTB domain-containing protein 7A | chr19 | GO:0006281 | Not Cancer Driver | No | 60 | 0.103 | 285 | 30 | 0.105 | 0 |
ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0006281 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |
ZRANB3 | ZRANB3 | Q5FWF4 | DNA annealing helicase and endonuclease ZRANB3 | chr2 | GO:0006281 | Not Cancer Driver | No | 126 | 0.117 | 261 | 31 | 0.119 | 0 |