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Total number of protein in "GO:0006139" GO term:  1113

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A1CF_ENST00000373993 A1CF Q9NQ94 APOBEC1 complementation factor chr10 GO:0006139 Census Yes 150 0.253 63 20 0.317 0
AADAT_ENST00000515480 AADAT Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial chr4 GO:0006139 Not Cancer Driver No 48 0.113 71 10 0.141 0
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0006139 Not Cancer Driver No 97 0.1 140 14 0.1 5
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 GO:0006139 Not Cancer Driver No 123 0.125 203 25 0.123 5
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 GO:0006139 Not Cancer Driver No 40 0.097 157 20 0.127 0
AASS AASS Q9UDR5 Alpha-aminoadipic semialdehyde synthase, mitochondrial chr7 GO:0006139 Not Cancer Driver No 161 0.174 18 3 0.167 0
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0006139 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABHD14B_ENST00000525795 ABHD14B Q96IU4 Putative protein-lysine deacylase ABHD14B chr3 GO:0006139 Not Cancer Driver No 12 0.057 17 2 0.118 0
ABT1 ABT1 Q9ULW3 Activator of basal transcription 1 chr6 GO:0006139 Not Cancer Driver No 56 0.206 157 30 0.191 0
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0006139 Not Cancer Driver No 388 0.158 342 62 0.181 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0006139 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0006139 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 GO:0006139 Not Cancer Driver No 120 0.109 114 12 0.105 0
ACOT12 ACOT12 Q8WYK0 Acetyl-coenzyme A thioesterase chr5 GO:0006139 Not Cancer Driver No 93 0.168 41 3 0.073 0
ACOT4 ACOT4 Q8N9L9 Peroxisomal succinyl-coenzyme A thioesterase chr14 GO:0006139 Not Cancer Driver No 53 0.126 13 1 0.077 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0006139 Not Cancer Driver No 43 0.113 77 16 0.208 0
ACPP_ENST00000336375 ACP3 P15309 Prostatic acid phosphatase chr3 GO:0006139 Not Cancer Driver No 81 0.21 24 5 0.208 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0006139 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACSBG2_ENST00000591403 ACSBG2 Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 chr19 GO:0006139 Not Cancer Driver No 119 0.179 37 9 0.243 0
ACSF3_ENST00000406948 ACSF3 Q4G176 Malonate--CoA ligase ACSF3, mitochondrial chr16 GO:0006139 Not Cancer Driver No 87 0.151 48 11 0.229 9
ACSL1_ENST00000281455 ACSL1 P33121 Long-chain-fatty-acid--CoA ligase 1 chr4 GO:0006139 Not Cancer Driver No 85 0.122 27 1 0.037 0
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0006139 Census, Compendium Yes 89 0.124 47 7 0.149 0
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0006139 Not Cancer Driver No 97 0.136 77 12 0.156 1
ACSL5_ENST00000354655 ACSL5 Q9ULC5 Long-chain-fatty-acid--CoA ligase 5 chr10 GO:0006139 Not Cancer Driver No 98 0.143 22 5 0.227 0
ACSL6_ENST00000379240 ACSL6 Q9UKU0 Long-chain-fatty-acid--CoA ligase 6 chr5 GO:0006139 Census Yes 120 0.172 34 3 0.088 0
ACSM2A_ENST00000219054 ACSM2A Q08AH3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial chr16 GO:0006139 Not Cancer Driver No 200 0.347 48 24 0.5 0
ACSS1 ACSS1 Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial chr20 GO:0006139 Not Cancer Driver No 79 0.115 76 6 0.079 0
ACSS2_ENST00000360596 ACSS2 Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic chr20 GO:0006139 Not Cancer Driver No 62 0.088 111 6 0.054 0
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 GO:0006139 Not Cancer Driver No 63 0.104 163 23 0.141 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0006139 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADA2 ADA2 Q9NZK5 Adenosine deaminase 2 chr22 GO:0006139 Not Cancer Driver No 97 0.19 1 0 0.0 10
ADAD1 ADAD1 Q96M93 Adenosine deaminase domain-containing protein 1 chr4 GO:0006139 Not Cancer Driver No 158 0.274 78 24 0.308 0
ADAD2_ENST00000315906 ADAD2 Q8NCV1 Adenosine deaminase domain-containing protein 2 chr16 GO:0006139 Not Cancer Driver No 87 0.149 191 39 0.204 0
ADAL ADAL Q6DHV7 Adenosine deaminase-like protein chr15 GO:0006139 Not Cancer Driver No 33 0.093 57 9 0.158 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0006139 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0006139 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADARB2 ADARB2 Q9NS39 Double-stranded RNA-specific editase B2 chr10 GO:0006139 Not Cancer Driver No 154 0.208 331 69 0.208 0
ADAT2 ADAT2 Q7Z6V5 tRNA-specific adenosine deaminase 2 chr6 GO:0006139 Not Cancer Driver No 26 0.136 69 9 0.13 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0006139 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY10 ADCY10 Q96PN6 Adenylate cyclase type 10 chr1 GO:0006139 Not Cancer Driver No 249 0.155 24 4 0.167 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0006139 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0006139 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY4_ENST00000554068 ADCY4 Q8NFM4 Adenylate cyclase type 4 chr14 GO:0006139 Not Cancer Driver No 137 0.127 94 23 0.245 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0006139 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0006139 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY7_ENST00000254235 ADCY7 P51828 Adenylate cyclase type 7 chr16 GO:0006139 Not Cancer Driver No 144 0.133 121 17 0.14 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0006139 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCY9 ADCY9 O60503 Adenylate cyclase type 9 chr16 GO:0006139 Not Cancer Driver No 195 0.144 271 42 0.155 0
ADK ADK P55263 Adenosine kinase chr10 GO:0006139 Not Cancer Driver No 29 0.08 33 2 0.061 3
ADPGK ADPGK Q9BRR6 ADP-dependent glucokinase chr15 GO:0006139 Not Cancer Driver No 38 0.076 24 0 0.0 0
ADPRHL2 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0006139 Not Cancer Driver No 32 0.088 49 4 0.082 1
ADSL ADSL P30566 Adenylosuccinate lyase chr22 GO:0006139 Not Cancer Driver No 68 0.14 36 9 0.25 27
ADSS ADSS2 P30520 Adenylosuccinate synthetase isozyme 2 chr1 GO:0006139 Not Cancer Driver No 49 0.107 48 4 0.083 0
ADSSL1_ENST00000330877 ADSS1 Q8N142 Adenylosuccinate synthetase isozyme 1 chr14 GO:0006139 Not Cancer Driver No 74 0.162 68 6 0.088 1
AFMID_ENST00000409257 AFMID Q63HM1 Kynurenine formamidase chr17 GO:0006139 Not Cancer Driver No 46 0.152 12 1 0.083 0
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 GO:0006139 Not Cancer Driver No 126 0.147 87 11 0.126 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0006139 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 GO:0006139 Not Cancer Driver No 110 0.128 143 19 0.133 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 GO:0006139 Not Cancer Driver No 100 0.116 183 24 0.131 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0006139 Not Cancer Driver No 56 0.283 0 0 0.0 8
AK1_ENST00000373176 AK1 P00568 Adenylate kinase isoenzyme 1 chr9 GO:0006139 Not Cancer Driver No 19 0.098 55 3 0.055 4
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 GO:0006139 Not Cancer Driver No 23 0.096 76 12 0.158 2
AK3 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 GO:0006139 Not Cancer Driver No 23 0.101 33 3 0.091 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 GO:0006139 Not Cancer Driver No 26 0.117 24 3 0.125 0
AK5 AK5 Q9Y6K8 Adenylate kinase isoenzyme 5 chr1 GO:0006139 Not Cancer Driver No 116 0.206 161 44 0.273 0
AK6 AK6 Q9Y3D8 Adenylate kinase isoenzyme 6 chr5 GO:0006139 Not Cancer Driver No 6 0.035 13 0 0.0 0
AK7 AK7 Q96M32 Adenylate kinase 7 chr14 GO:0006139 Not Cancer Driver No 126 0.174 181 42 0.232 1
AK8 AK8 Q96MA6 Adenylate kinase 8 chr9 GO:0006139 Not Cancer Driver No 74 0.154 53 8 0.151 0
AK9 AK9 Q5TCS8 Adenylate kinase 9 chr6 GO:0006139 Not Cancer Driver No 235 0.123 589 58 0.098 0
ALDH6A1 ALDH6A1 Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial chr14 GO:0006139 Not Cancer Driver No 54 0.101 83 11 0.133 1
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0006139 Not Cancer Driver No 55 0.141 77 11 0.143 0
ALKBH2_ENST00000343075 ALKBH2 Q6NS38 DNA oxidative demethylase ALKBH2 chr12 GO:0006139 Not Cancer Driver No 34 0.13 73 14 0.192 0
ALKBH3 ALKBH3 Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 chr11 GO:0006139 Not Cancer Driver No 42 0.147 157 25 0.159 0
ALKBH4 ALKBH4 Q9NXW9 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 chr7 GO:0006139 Not Cancer Driver No 39 0.129 14 2 0.143 0
ALKBH5 ALKBH5 Q6P6C2 RNA demethylase ALKBH5 chr17 GO:0006139 Not Cancer Driver No 41 0.104 200 23 0.115 0
AMD1 AMD1 P17707 S-adenosylmethionine decarboxylase proenzyme chr6 GO:0006139 Not Cancer Driver No 42 0.126 9 1 0.111 0
AMDHD2_ENST00000293971 AMDHD2 Q9Y303 N-acetylglucosamine-6-phosphate deacetylase chr16 GO:0006139 Not Cancer Driver No 44 0.108 25 6 0.24 0
AMPD1 AMPD1 P23109 AMP deaminase 1 chr1 GO:0006139 Not Cancer Driver No 218 0.292 112 25 0.223 2
AMPD2_ENST00000528667 AMPD2 Q01433 AMP deaminase 2 chr1 GO:0006139 Not Cancer Driver No 93 0.106 275 27 0.098 3
AMPD3_ENST00000529507 AMPD3 Q01432 AMP deaminase 3 chr11 GO:0006139 Not Cancer Driver No 132 0.172 207 38 0.184 10
ANG ANG P03950 Angiogenin chr14 GO:0006139 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGEL1 ANGEL1 Q9UNK9 Protein angel homolog 1 chr14 GO:0006139 Not Cancer Driver No 85 0.127 160 21 0.131 0
ANGEL2 ANGEL2 Q5VTE6 Protein angel homolog 2 chr1 GO:0006139 Not Cancer Driver No 56 0.103 48 6 0.125 0
ANKRD31 ANKRD31 Q8N7Z5 Ankyrin repeat domain-containing protein 31 chr5 GO:0006139 Not Cancer Driver No 62 0.033 1144 34 0.03 0
AP000311.1 AP000311.1 H7C0C1 ATP synthase subunit O, mitochondrial (Fragment) chr21 GO:0006139 Not Cancer Driver No 27 0.112 27 5 0.185 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0006139 Not Cancer Driver No 126 0.115 316 31 0.098 1
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0006139 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0006139 Not Cancer Driver No 64 0.125 407 57 0.14 0
APOBEC1 APOBEC1 P41238 C->U-editing enzyme APOBEC-1 chr12 GO:0006139 Not Cancer Driver No 62 0.263 13 1 0.077 0
APOBEC2 APOBEC2 Q9Y235 C->U-editing enzyme APOBEC-2 chr6 GO:0006139 Not Cancer Driver No 38 0.17 36 3 0.083 0
APOBEC3A_ENST00000249116 APOBEC3A P31941 DNA dC->dU-editing enzyme APOBEC-3A chr22 GO:0006139 Not Cancer Driver No 27 0.136 8 1 0.125 0
APOBEC3B APOBEC3B Q9UH17 DNA dC->dU-editing enzyme APOBEC-3B chr22 GO:0006139 Census Yes 61 0.16 1 0 0.0 0
APOBEC3C APOBEC3C Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C chr22 GO:0006139 Not Cancer Driver No 28 0.147 2 0 0.0 0
APOBEC3D APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 GO:0006139 Not Cancer Driver No 43 0.111 3 0 0.0 0
APOBEC3F APOBEC3F Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F chr22 GO:0006139 Not Cancer Driver No 49 0.131 0 0 0.0 0
APOBEC3G APOBEC3G Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G chr22 GO:0006139 Not Cancer Driver No 61 0.159 0 0 0.0 0
APOBEC3H_ENST00000613677 APOBEC3H Q6NTF7 DNA dC->dU-editing enzyme APOBEC-3H chr22 GO:0006139 Not Cancer Driver No 39 0.195 0 0 0.0 0
APRT APRT P07741 Adenine phosphoribosyltransferase chr16 GO:0006139 Not Cancer Driver No 16 0.089 0 0 0.0 8
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0006139 Not Cancer Driver No 36 0.101 101 6 0.059 9
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 GO:0006139 Not Cancer Driver No 279 0.127 87 8 0.092 0
ASPDH ASPDH A6ND91 Aspartate dehydrogenase domain-containing protein chr19 GO:0006139 Not Cancer Driver No 27 0.095 81 5 0.062 0
ASZ1 ASZ1 Q8WWH4 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 chr7 GO:0006139 Not Cancer Driver No 86 0.181 53 10 0.189 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0006139 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0006139 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0006139 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 GO:0006139 Compendium Yes 160 0.126 1136 139 0.122 0
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 GO:0006139 Census Yes 74 0.125 25 1 0.04 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0006139 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0006139 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0006139 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 GO:0006139 Not Cancer Driver No 39 0.131 11 0 0.0 0
ATP5F1D_ENST00000591660 ATP5F1D P30049 ATP synthase subunit delta, mitochondrial chr19 GO:0006139 Not Cancer Driver No 7 0.042 5 1 0.2 2
ATP5F1E_ENST00000395663 ATP5F1E P56381 ATP synthase subunit epsilon, mitochondrial chr20 GO:0006139 Not Cancer Driver No 3 0.059 1 0 0.0 1
ATP5ME ATP5ME P56385 ATP synthase subunit e, mitochondrial chr4 GO:0006139 Not Cancer Driver No 6 0.087 18 2 0.111 0
ATP5MF ATP5MF P56134 ATP synthase subunit f, mitochondrial chr7 GO:0006139 Not Cancer Driver No 22 0.234 0 0 0.0 0
ATP5MG ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 GO:0006139 Not Cancer Driver No 16 0.155 0 0 0.0 0
ATP5PB ATP5PB P24539 ATP synthase F(0) complex subunit B1, mitochondrial chr1 GO:0006139 Not Cancer Driver No 37 0.145 2 0 0.0 0
ATP5PD ATP5PD O75947 ATP synthase subunit d, mitochondrial chr17 GO:0006139 Not Cancer Driver No 12 0.075 15 0 0.0 0
ATP5PF_ENST00000400090 ATP5PF P18859 ATP synthase-coupling factor 6, mitochondrial chr21 GO:0006139 Not Cancer Driver No 14 0.13 15 1 0.067 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 GO:0006139 Not Cancer Driver No 19 0.089 9 2 0.222 0
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0006139 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0006139 Census, Compendium Yes 114 0.135 547 77 0.141 0
B4GALNT2 B4GALNT2 Q8NHY0 Beta-1,4 N-acetylgalactosaminyltransferase 2 chr17 GO:0006139 Not Cancer Driver No 109 0.193 22 5 0.227 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0006139 Not Cancer Driver No 10 0.112 11 2 0.182 1
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0006139 Not Cancer Driver No 28 0.224 119 25 0.21 0
BAZ2A BAZ2A Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A chr12 GO:0006139 Not Cancer Driver No 186 0.098 1283 118 0.092 0
BCDIN3D BCDIN3D Q7Z5W3 RNA 5'-monophosphate methyltransferase chr12 GO:0006139 Not Cancer Driver No 27 0.092 44 2 0.045 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0006139 Census, Compendium Yes 156 0.174 699 114 0.163 2
BEND3_ENST00000369042 BEND3 Q5T5X7 BEN domain-containing protein 3 chr6 GO:0006139 Not Cancer Driver No 104 0.126 311 44 0.141 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0006139 Census Yes 153 0.108 667 70 0.105 8
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0006139 Not Cancer Driver No 12 0.07 111 11 0.099 0
BOP1 BOP1 Q14137 Ribosome biogenesis protein BOP1 chr8 GO:0006139 Not Cancer Driver No 20 0.027 304 19 0.062 0
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 GO:0006139 Not Cancer Driver No 44 0.143 9 0 0.0 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0006139 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0006139 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0006139 Census Yes 174 0.139 397 59 0.149 6
BTBD18 BTBD18 B2RXH4 BTB/POZ domain-containing protein 18 chr11 GO:0006139 Not Cancer Driver No 29 0.041 567 25 0.044 0
BUD23_ENST00000265758 BUD23 O43709 Probable 18S rRNA (guanine-N(7))-methyltransferase chr7 GO:0006139 Not Cancer Driver No 41 0.146 83 11 0.133 0
C14orf39 SIX6OS1 Q8N1H7 Protein SIX6OS1 chr14 GO:0006139 Not Cancer Driver No 128 0.218 326 76 0.233 0
C19orf57_ENST00000586783 BRME1 Q0VDD7 Break repair meiotic recombinase recruitment factor 1 chr19 GO:0006139 Not Cancer Driver No 91 0.136 632 88 0.139 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0006139 Not Cancer Driver No 71 0.203 0 0 0.0 0
C9orf64 C9orf64 Q5T6V5 Queuosine salvage protein chr9 GO:0006139 Not Cancer Driver No 43 0.126 1 0 0.0 0
CAD CAD P27708 CAD protein chr2 GO:0006139 Not Cancer Driver No 287 0.129 368 52 0.141 1
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0006139 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARS2 CARS2 Q9HA77 Probable cysteine--tRNA ligase, mitochondrial chr13 GO:0006139 Not Cancer Driver No 51 0.09 87 8 0.092 1
CARS_ENST00000397111 CARS1 P49589 Cysteine--tRNA ligase, cytoplasmic chr11 GO:0006139 Not Cancer Driver No 97 0.13 184 35 0.19 3
CASK_ENST00000378163 CASK O14936 Peripheral plasma membrane protein CASK chrX GO:0006139 Not Cancer Driver No 118 0.127 285 45 0.158 4
CAVIN1 CAVIN1 Q6NZI2 Caveolae-associated protein 1 chr17 GO:0006139 Not Cancer Driver No 66 0.169 280 50 0.179 0
CBLL1 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 GO:0006139 Not Cancer Driver No 72 0.147 373 49 0.131 0
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 GO:0006139 Not Cancer Driver No 61 0.111 160 19 0.119 103
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0006139 Not Cancer Driver No 56 0.15 13 2 0.154 0
CD3EAP_ENST00000309424 POLR1G O15446 DNA-directed RNA polymerase I subunit RPA34 chr19 GO:0006139 Not Cancer Driver No 52 0.102 491 50 0.102 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0006139 Not Cancer Driver No 56 0.215 24 7 0.292 32
CDA CDA P32320 Cytidine deaminase chr1 GO:0006139 Not Cancer Driver No 21 0.144 8 0 0.0 0
CDADC1 CDADC1 Q9BWV3 Cytidine and dCMP deaminase domain-containing protein 1 chr13 GO:0006139 Not Cancer Driver No 52 0.101 122 13 0.107 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0006139 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK7 CDK7 P50613 Cyclin-dependent kinase 7 chr5 GO:0006139 Not Cancer Driver No 41 0.118 38 5 0.132 0
CDKAL1 CDKAL1 Q5VV42 Threonylcarbamoyladenosine tRNA methylthiotransferase chr6 GO:0006139 Not Cancer Driver No 80 0.138 120 14 0.117 0
CECR2_ENST00000342247 CECR2 Q9BXF3 Cat eye syndrome critical region protein 2 chr22 GO:0006139 Not Cancer Driver No 222 0.15 1192 183 0.154 0
CELF3 CELF3 Q5SZQ8 CUGBP Elav-like family member 3 chr1 GO:0006139 Not Cancer Driver No 82 0.176 201 33 0.164 0
CMPK2 CMPK2 Q5EBM0 UMP-CMP kinase 2, mitochondrial chr2 GO:0006139 Not Cancer Driver No 41 0.091 99 8 0.081 0
CMTR1 CMTR1 Q8N1G2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 chr6 GO:0006139 Not Cancer Driver No 81 0.097 176 20 0.114 0
CMTR2 CMTR2 Q8IYT2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 chr16 GO:0006139 Compendium Yes 101 0.131 10 2 0.2 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:0006139 Census Yes 11 0.062 19 0 0.0 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0006139 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 GO:0006139 Not Cancer Driver No 84 0.156 354 66 0.186 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 GO:0006139 Not Cancer Driver No 58 0.105 37 3 0.081 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0006139 Not Cancer Driver No 65 0.117 66 4 0.061 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0006139 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0006139 Not Cancer Driver No 30 0.103 6 0 0.0 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0006139 Not Cancer Driver No 36 0.086 71 2 0.028 0
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 GO:0006139 Not Cancer Driver No 57 0.101 50 4 0.08 1
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0006139 Not Cancer Driver No 368 0.245 73 22 0.301 140
CPSF1 CPSF1 Q10570 Cleavage and polyadenylation specificity factor subunit 1 chr8 GO:0006139 Not Cancer Driver No 177 0.123 298 42 0.141 0
CPSF2 CPSF2 Q9P2I0 Cleavage and polyadenylation specificity factor subunit 2 chr14 GO:0006139 Not Cancer Driver No 76 0.097 231 22 0.095 0
CPSF3 CPSF3 Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 chr2 GO:0006139 Not Cancer Driver No 78 0.114 56 9 0.161 0
CPSF4 CPSF4 O95639 Cleavage and polyadenylation specificity factor subunit 4 chr7 GO:0006139 Not Cancer Driver No 36 0.134 89 11 0.124 0
CPSF4L CPSF4L A6NMK7 Putative cleavage and polyadenylation specificity factor subunit 4-like protein chr17 GO:0006139 Not Cancer Driver No 7 0.039 0 0 0.0 0
CPSF6_ENST00000435070 CPSF6 Q16630 Cleavage and polyadenylation specificity factor subunit 6 chr12 GO:0006139 Not Cancer Driver No 85 0.154 484 75 0.155 0
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 GO:0006139 Not Cancer Driver No 55 0.117 398 52 0.131 0
CRCP CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 GO:0006139 Not Cancer Driver No 11 0.074 113 4 0.035 0
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 GO:0006139 Not Cancer Driver No 122 0.213 96 15 0.156 0
CROT_ENST00000331536 CROT Q9UKG9 Peroxisomal carnitine O-octanoyltransferase chr7 GO:0006139 Not Cancer Driver No 107 0.175 32 2 0.062 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0006139 Not Cancer Driver No 72 0.121 100 12 0.12 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0006139 Not Cancer Driver No 118 0.148 204 29 0.142 0
CSGALNACT1_ENST00000332246 CSGALNACT1 Q8TDX6 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 chr8 GO:0006139 Not Cancer Driver No 91 0.171 131 28 0.214 0
CSTF2T CSTF2T Q9H0L4 Cleavage stimulation factor subunit 2 tau variant chr10 GO:0006139 Not Cancer Driver No 87 0.141 507 75 0.148 0
CSTF2_ENST00000372972 CSTF2 P33240 Cleavage stimulation factor subunit 2 chrX GO:0006139 Not Cancer Driver No 85 0.147 484 72 0.149 0
CSTF3 CSTF3 Q12996 Cleavage stimulation factor subunit 3 chr11 GO:0006139 Not Cancer Driver No 82 0.114 122 15 0.123 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 GO:0006139 Census, Compendium Yes 151 0.208 481 83 0.173 1
CTCFL_ENST00000371196 CTCFL Q8NI51 Transcriptional repressor CTCFL chr20 GO:0006139 Not Cancer Driver No 136 0.205 266 61 0.229 0
CTPS1 CTPS1 P17812 CTP synthase 1 chr1 GO:0006139 Not Cancer Driver No 70 0.118 83 10 0.12 0
CTPS2_ENST00000380241 CTPS2 Q9NRF8 CTP synthase 2 chrX GO:0006139 Not Cancer Driver No 57 0.097 65 9 0.138 0
CTU1 CTU1 Q7Z7A3 Cytoplasmic tRNA 2-thiolation protein 1 chr19 GO:0006139 Not Cancer Driver No 12 0.034 60 1 0.017 0
CTU2_ENST00000453996 CTU2 Q2VPK5 Cytoplasmic tRNA 2-thiolation protein 2 chr16 GO:0006139 Not Cancer Driver No 46 0.089 137 11 0.08 0
CUL4B CUL4B Q13620 Cullin-4B chrX GO:0006139 Not Cancer Driver No 138 0.151 207 38 0.184 2
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0006139 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0006139 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYREN CYREN Q9BWK5 Cell cycle regulator of non-homologous end joining chr7 GO:0006139 Not Cancer Driver No 24 0.153 128 19 0.148 0
DALRD3 DALRD3 Q5D0E6 DALR anticodon-binding domain-containing protein 3 chr3 GO:0006139 Not Cancer Driver No 49 0.09 40 4 0.1 0
DARS DARS1 P14868 Aspartate--tRNA ligase, cytoplasmic chr2 GO:0006139 Not Cancer Driver No 55 0.11 110 21 0.191 8
DARS2 DARS2 Q6PI48 Aspartate--tRNA ligase, mitochondrial chr1 GO:0006139 Not Cancer Driver No 63 0.098 91 11 0.121 11
DCAKD DCAKD Q8WVC6 Dephospho-CoA kinase domain-containing protein chr17 GO:0006139 Not Cancer Driver No 31 0.134 2 0 0.0 0
DCK DCK P27707 Deoxycytidine kinase chr4 GO:0006139 Not Cancer Driver No 29 0.112 22 4 0.182 0
DCLRE1A DCLRE1A Q6PJP8 DNA cross-link repair 1A protein chr10 GO:0006139 Not Cancer Driver No 92 0.088 514 45 0.088 0
DCLRE1B DCLRE1B Q9H816 5' exonuclease Apollo chr1 GO:0006139 Not Cancer Driver No 65 0.122 127 17 0.134 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:0006139 Not Cancer Driver No 76 0.11 277 26 0.094 3
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 GO:0006139 Not Cancer Driver No 46 0.079 382 31 0.081 0
DCP1B DCP1B Q8IZD4 mRNA-decapping enzyme 1B chr12 GO:0006139 Not Cancer Driver No 82 0.133 406 63 0.155 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0006139 Not Cancer Driver No 57 0.136 167 24 0.144 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0006139 Not Cancer Driver No 48 0.142 53 6 0.113 1
DCTD_ENST00000438320 DCTD P32321 Deoxycytidylate deaminase chr4 GO:0006139 Not Cancer Driver No 33 0.185 3 0 0.0 0
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 GO:0006139 Not Cancer Driver No 14 0.082 88 9 0.102 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0006139 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0006139 Census, Compendium Yes 45 0.105 70 5 0.071 2
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 GO:0006139 Not Cancer Driver No 91 0.125 362 48 0.133 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0006139 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX23 DDX23 Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 chr12 GO:0006139 Not Cancer Driver No 121 0.148 426 71 0.167 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 GO:0006139 Not Cancer Driver No 49 0.114 34 8 0.235 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0006139 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX4 DDX4 Q9NQI0 Probable ATP-dependent RNA helicase DDX4 chr5 GO:0006139 Not Cancer Driver No 115 0.159 315 49 0.156 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0006139 Census Yes 74 0.121 225 23 0.102 0
DEDD2 DEDD2 Q8WXF8 DNA-binding death effector domain-containing protein 2 chr19 GO:0006139 Not Cancer Driver No 42 0.129 133 25 0.188 0
DERA DERA Q9Y315 Deoxyribose-phosphate aldolase chr12 GO:0006139 Not Cancer Driver No 33 0.104 2 0 0.0 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0006139 Not Cancer Driver No 47 0.142 113 18 0.159 0
DFFB_ENST00000378209 DFFB O76075 DNA fragmentation factor subunit beta chr1 GO:0006139 Not Cancer Driver No 37 0.109 27 1 0.037 0
DGAT1 DGAT1 O75907 Diacylglycerol O-acyltransferase 1 chr8 GO:0006139 Not Cancer Driver No 52 0.107 62 0 0.0 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0006139 Not Cancer Driver No 56 0.144 17 2 0.118 0
DGCR8 DGCR8 Q8WYQ5 Microprocessor complex subunit DGCR8 chr22 GO:0006139 Census, Compendium Yes 102 0.132 466 57 0.122 0
DGUOK DGUOK Q16854 Deoxyguanosine kinase, mitochondrial chr2 GO:0006139 Not Cancer Driver No 25 0.09 17 1 0.059 6
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 GO:0006139 Not Cancer Driver No 25 0.134 20 0 0.0 0
DHODH DHODH Q02127 Dihydroorotate dehydrogenase (quinone), mitochondrial chr16 GO:0006139 Not Cancer Driver No 44 0.111 96 11 0.115 10
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0006139 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0006139 Compendium Yes 182 0.143 331 42 0.127 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0006139 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 GO:0006139 Not Cancer Driver No 204 0.13 396 53 0.134 0
DIS3 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 GO:0006139 Compendium Yes 121 0.126 235 32 0.136 0
DIS3L DIS3L Q8TF46 DIS3-like exonuclease 1 chr15 GO:0006139 Not Cancer Driver No 111 0.105 139 20 0.144 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0006139 Not Cancer Driver No 114 0.129 264 22 0.083 1
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0006139 Not Cancer Driver No 62 0.121 145 29 0.2 24
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 GO:0006139 Not Cancer Driver No 63 0.097 294 42 0.143 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 GO:0006139 Not Cancer Driver No 67 0.132 17 0 0.0 10
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0006139 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG2_ENST00000398309 DLG2 Q15700 Disks large homolog 2 chr11 GO:0006139 Not Cancer Driver No 224 0.257 303 107 0.353 0
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 GO:0006139 Not Cancer Driver No 53 0.117 190 32 0.168 1
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:0006139 Not Cancer Driver No 49 0.105 269 28 0.104 0
DMC1 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 GO:0006139 Not Cancer Driver No 39 0.115 49 5 0.102 0
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0006139 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 GO:0006139 Not Cancer Driver No 52 0.145 141 21 0.149 2
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0006139 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE2 DNASE2 O00115 Deoxyribonuclease-2-alpha chr19 GO:0006139 Not Cancer Driver No 46 0.128 48 7 0.146 0
DNASE2B DNASE2B Q8WZ79 Deoxyribonuclease-2-beta chr1 GO:0006139 Not Cancer Driver No 53 0.147 14 1 0.071 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0006139 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0006139 Census, Compendium Yes 194 0.213 371 59 0.159 16
DNMT3B DNMT3B Q9UBC3 DNA (cytosine-5)-methyltransferase 3B chr20 GO:0006139 Not Cancer Driver No 153 0.179 328 71 0.216 16
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:0006139 Not Cancer Driver No 83 0.215 10 1 0.1 0
DNPH1 DNPH1 O43598 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 chr6 GO:0006139 Not Cancer Driver No 15 0.086 49 3 0.061 0
DNTT DNTT P04053 DNA nucleotidylexotransferase chr10 GO:0006139 Not Cancer Driver No 106 0.208 66 16 0.242 0
DONSON DONSON Q9NYP3 Protein downstream neighbor of Son chr21 GO:0006139 Not Cancer Driver No 50 0.088 217 13 0.06 6
DPM1_ENST00000371588 DPM1 O60762 Dolichol-phosphate mannosyltransferase subunit 1 chr20 GO:0006139 Not Cancer Driver No 38 0.146 29 6 0.207 3
DPYD DPYD Q12882 Dihydropyrimidine dehydrogenase [NADP(+)] chr1 GO:0006139 Not Cancer Driver No 303 0.296 77 23 0.299 3
DPYS DPYS Q14117 Dihydropyrimidinase chr8 GO:0006139 Not Cancer Driver No 148 0.285 103 28 0.272 5
DPYSL2_ENST00000311151 DPYSL2 Q16555 Dihydropyrimidinase-related protein 2 chr8 GO:0006139 Not Cancer Driver No 86 0.15 146 32 0.219 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0006139 Census, Compendium Yes 175 0.127 682 100 0.147 0
DTD1 DTD1 Q8TEA8 D-aminoacyl-tRNA deacylase 1 chr20 GO:0006139 Not Cancer Driver No 45 0.215 93 26 0.28 0
DTD2_ENST00000356180 DTD2 Q96FN9 D-aminoacyl-tRNA deacylase 2 chr14 GO:0006139 Not Cancer Driver No 12 0.071 11 1 0.091 0
DTYMK DTYMK P23919 Thymidylate kinase chr2 GO:0006139 Not Cancer Driver No 10 0.047 0 0 0.0 0
DUS1L_ENST00000306796 DUS1L Q6P1R4 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like chr17 GO:0006139 Not Cancer Driver No 52 0.11 110 10 0.091 0
DUS2 DUS2 Q9NX74 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like chr16 GO:0006139 Not Cancer Driver No 48 0.097 117 10 0.085 0
DUS3L DUS3L Q96G46 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like chr19 GO:0006139 Not Cancer Driver No 82 0.126 234 27 0.115 0
DUS4L DUS4L O95620 tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like chr7 GO:0006139 Not Cancer Driver No 38 0.12 3 0 0.0 0
DUT DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 GO:0006139 Not Cancer Driver No 19 0.075 128 8 0.062 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0006139 Not Cancer Driver No 46 0.116 143 17 0.119 0
EARS2_ENST00000449606 EARS2 Q5JPH6 Probable glutamate--tRNA ligase, mitochondrial chr16 GO:0006139 Not Cancer Driver No 56 0.107 99 14 0.141 14
EDC3 EDC3 Q96F86 Enhancer of mRNA-decapping protein 3 chr15 GO:0006139 Not Cancer Driver No 43 0.085 185 22 0.119 1
EDC4 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 GO:0006139 Not Cancer Driver No 144 0.103 702 69 0.098 0
EFL1 EFL1 Q7Z2Z2 Elongation factor-like GTPase 1 chr15 GO:0006139 Not Cancer Driver No 128 0.114 329 37 0.112 0
EHMT1 EHMT1 Q9H9B1 Histone-lysine N-methyltransferase EHMT1 chr9 GO:0006139 Not Cancer Driver No 182 0.14 701 97 0.138 1
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0006139 Not Cancer Driver No 142 0.117 585 71 0.121 0
ELAC1 ELAC1 Q9H777 Zinc phosphodiesterase ELAC protein 1 chr18 GO:0006139 Not Cancer Driver No 40 0.11 47 4 0.085 0
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 GO:0006139 Not Cancer Driver No 86 0.104 208 30 0.144 10
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0006139 Census, Compendium Yes 67 0.108 446 53 0.119 0
ELL2 ELL2 O00472 RNA polymerase II elongation factor ELL2 chr5 GO:0006139 Not Cancer Driver No 90 0.141 421 63 0.15 0
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0006139 Not Cancer Driver No 50 0.126 186 13 0.07 0
ELOVL1_ENST00000372458 ELOVL1 Q9BW60 Elongation of very long chain fatty acids protein 1 chr1 GO:0006139 Not Cancer Driver No 32 0.115 0 0 0.0 1
ELOVL2 ELOVL2 Q9NXB9 Elongation of very long chain fatty acids protein 2 chr6 GO:0006139 Not Cancer Driver No 57 0.193 8 2 0.25 0
ELOVL3 ELOVL3 Q9HB03 Elongation of very long chain fatty acids protein 3 chr10 GO:0006139 Not Cancer Driver No 42 0.156 1 1 1.0 0
ELOVL4 ELOVL4 Q9GZR5 Elongation of very long chain fatty acids protein 4 chr6 GO:0006139 Not Cancer Driver No 68 0.217 23 6 0.261 1
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 GO:0006139 Not Cancer Driver No 34 0.114 25 4 0.16 2
ELOVL6 ELOVL6 Q9H5J4 Elongation of very long chain fatty acids protein 6 chr4 GO:0006139 Not Cancer Driver No 40 0.151 0 0 0.0 0
ELOVL7_ENST00000425382 ELOVL7 A1L3X0 Elongation of very long chain fatty acids protein 7 chr5 GO:0006139 Not Cancer Driver No 41 0.146 10 2 0.2 0
ELP1 ELP1 O95163 Elongator complex protein 1 chr9 GO:0006139 Not Cancer Driver No 143 0.107 157 23 0.146 2
ELP3 ELP3 Q9H9T3 Elongator complex protein 3 chr8 GO:0006139 Not Cancer Driver No 60 0.11 19 4 0.211 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0006139 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0006139 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENO2 ENO2 P09104 Gamma-enolase chr12 GO:0006139 Not Cancer Driver No 48 0.111 12 2 0.167 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0006139 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENPP4 ENPP4 Q9Y6X5 Bis(5'-adenosyl)-triphosphatase ENPP4 chr6 GO:0006139 Not Cancer Driver No 79 0.174 20 4 0.2 0
ENTPD1_ENST00000371205 ENTPD1 P49961 Ectonucleoside triphosphate diphosphohydrolase 1 chr10 GO:0006139 Not Cancer Driver No 63 0.124 16 2 0.125 1
ENTPD2 ENTPD2 Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 chr9 GO:0006139 Not Cancer Driver No 36 0.073 32 0 0.0 0
ENTPD3 ENTPD3 O75355 Ectonucleoside triphosphate diphosphohydrolase 3 chr3 GO:0006139 Not Cancer Driver No 64 0.121 14 2 0.143 0
ENTPD4 ENTPD4 Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 chr8 GO:0006139 Not Cancer Driver No 67 0.109 26 2 0.077 0
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0006139 Not Cancer Driver No 41 0.096 6 1 0.167 0
ENTPD6 ENTPD6 O75354 Ectonucleoside triphosphate diphosphohydrolase 6 chr20 GO:0006139 Not Cancer Driver No 68 0.14 41 6 0.146 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0006139 Not Cancer Driver No 90 0.149 26 3 0.115 0
ENTPD8 ENTPD8 Q5MY95 Ectonucleoside triphosphate diphosphohydrolase 8 chr9 GO:0006139 Not Cancer Driver No 46 0.093 5 0 0.0 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0006139 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0006139 Compendium Yes 171 0.175 187 39 0.209 3
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 GO:0006139 Not Cancer Driver No 204 0.135 372 62 0.167 1
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0006139 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0006139 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0006139 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0006139 Census Yes 120 0.131 225 27 0.12 15
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0006139 Census Yes 175 0.148 816 121 0.148 6
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0006139 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0006139 Not Cancer Driver No 25 0.063 53 8 0.151 7
EREG EREG O14944 Proepiregulin chr4 GO:0006139 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERH ERH P84090 Enhancer of rudimentary homolog chr14 GO:0006139 Not Cancer Driver No 7 0.067 11 0 0.0 0
ERI1_ENST00000519292 ERI1 Q8IV48 3'-5' exoribonuclease 1 chr8 GO:0006139 Not Cancer Driver No 40 0.115 78 13 0.167 0
ERI2 ERI2 A8K979 ERI1 exoribonuclease 2 chr16 GO:0006139 Not Cancer Driver No 34 0.049 288 8 0.028 0
ERI3 ERI3 O43414 ERI1 exoribonuclease 3 chr1 GO:0006139 Not Cancer Driver No 49 0.145 29 0 0.0 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0006139 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0006139 Not Cancer Driver No 192 0.207 213 45 0.211 0
EXD1_ENST00000314992 EXD1 Q8NHP7 piRNA biogenesis protein EXD1 chr15 GO:0006139 Not Cancer Driver No 85 0.165 173 26 0.15 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 GO:0006139 Not Cancer Driver No 58 0.093 176 15 0.085 0
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0006139 Not Cancer Driver No 123 0.145 472 76 0.161 0
EXOG EXOG Q9Y2C4 Nuclease EXOG, mitochondrial chr3 GO:0006139 Not Cancer Driver No 42 0.114 52 1 0.019 0
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0006139 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 GO:0006139 Not Cancer Driver No 21 0.072 47 6 0.128 2
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0006139 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:0006139 Not Cancer Driver No 34 0.139 23 0 0.0 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 GO:0006139 Not Cancer Driver No 43 0.183 31 3 0.097 0
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0006139 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0006139 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0006139 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0006139 Not Cancer Driver No 58 0.132 154 18 0.117 1
EXTL2 EXTL2 Q9UBQ6 Exostosin-like 2 chr1 GO:0006139 Not Cancer Driver No 50 0.152 0 0 0.0 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0006139 Census, Compendium Yes 120 0.161 284 44 0.155 11
FAM111A FAM111A Q96PZ2 Serine protease FAM111A chr11 GO:0006139 Not Cancer Driver No 78 0.128 169 23 0.136 5
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0006139 Not Cancer Driver No 109 0.127 24 5 0.208 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0006139 Census, Compendium Yes 176 0.121 181 14 0.077 3
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0006139 Not Cancer Driver No 268 0.131 898 128 0.143 0
FAR1 FAR1 Q8WVX9 Fatty acyl-CoA reductase 1 chr11 GO:0006139 Not Cancer Driver No 66 0.128 0 0 0.0 4
FAR2 FAR2 Q96K12 Fatty acyl-CoA reductase 2 chr12 GO:0006139 Not Cancer Driver No 63 0.122 0 0 0.0 0
FARS2_ENST00000274680 FARS2 O95363 Phenylalanine--tRNA ligase, mitochondrial chr6 GO:0006139 Not Cancer Driver No 66 0.146 73 17 0.233 4
FARSA FARSA Q9Y285 Phenylalanine--tRNA ligase alpha subunit chr19 GO:0006139 Not Cancer Driver No 75 0.148 120 25 0.208 0
FARSB FARSB Q9NSD9 Phenylalanine--tRNA ligase beta subunit chr2 GO:0006139 Not Cancer Driver No 71 0.121 0 0 0.0 8
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0006139 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBL FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 GO:0006139 Not Cancer Driver No 46 0.143 145 22 0.152 0
FBLL1 FBLL1 A6NHQ2 rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 chr5 GO:0006139 Not Cancer Driver No 18 0.054 140 1 0.007 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0006139 Census Yes 35 0.092 111 11 0.099 0
FHIT_ENST00000492590 FHIT P49789 Bis(5'-adenosyl)-triphosphatase chr3 GO:0006139 Census, Compendium Yes 35 0.238 45 9 0.2 0
FIP1L1 FIP1L1 Q6UN15 Pre-mRNA 3'-end-processing factor FIP1 chr4 GO:0006139 Census Yes 88 0.148 572 85 0.149 0
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0006139 Not Cancer Driver No 28 0.107 0 0 0.0 1
FKBP6 FKBP6 O75344 Inactive peptidyl-prolyl cis-trans isomerase FKBP6 chr7 GO:0006139 Not Cancer Driver No 75 0.229 17 1 0.059 0
FLAD1 FLAD1 Q8NFF5 FAD synthase chr1 GO:0006139 Not Cancer Driver No 81 0.138 59 6 0.102 1
FOS FOS P01100 Protein c-Fos chr14 GO:0006139 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXE3 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0006139 Not Cancer Driver No 12 0.038 186 4 0.022 6
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 GO:0006139 Not Cancer Driver No 97 0.132 511 65 0.127 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0006139 Not Cancer Driver No 79 0.12 548 64 0.117 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0006139 Census, Compendium Yes 39 0.104 257 20 0.078 26
FPGS FPGS Q05932 Folylpolyglutamate synthase, mitochondrial chr9 GO:0006139 Not Cancer Driver No 68 0.116 141 18 0.128 0
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0006139 Not Cancer Driver No 67 0.133 53 10 0.189 3
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX GO:0006139 Not Cancer Driver No 44 0.134 89 14 0.157 0
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 GO:0006139 Not Cancer Driver No 103 0.122 533 66 0.124 0
FUK FCSK Q8N0W3 L-fucose kinase chr16 GO:0006139 Not Cancer Driver No 102 0.094 26 1 0.038 0
FUT8_ENST00000394586 FUT8 Q9BYC5 Alpha-(1,6)-fucosyltransferase chr14 GO:0006139 Not Cancer Driver No 79 0.137 80 19 0.237 1
GALK1 GALK1 P51570 Galactokinase chr17 GO:0006139 Not Cancer Driver No 31 0.079 43 5 0.116 11
GALT GALT P07902 Galactose-1-phosphate uridylyltransferase chr9 GO:0006139 Not Cancer Driver No 42 0.111 149 9 0.06 134
GAR1 GAR1 Q9NY12 H/ACA ribonucleoprotein complex subunit 1 chr4 GO:0006139 Not Cancer Driver No 23 0.106 141 14 0.099 0
GARS GARS1 P41250 Glycine--tRNA ligase chr7 GO:0006139 Not Cancer Driver No 61 0.083 75 9 0.12 17
GART_ENST00000381815 GART P22102 Trifunctional purine biosynthetic protein adenosine-3 chr21 GO:0006139 Not Cancer Driver No 96 0.095 50 6 0.12 0
GATAD2A_ENST00000360315 GATAD2A Q86YP4 Transcriptional repressor p66-alpha chr19 GO:0006139 Not Cancer Driver No 88 0.139 548 77 0.141 0
GATB GATB O75879 Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial chr4 GO:0006139 Not Cancer Driver No 79 0.142 138 26 0.188 0
GATC GATC O43716 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial chr12 GO:0006139 Not Cancer Driver No 18 0.132 27 4 0.148 1
GCDH_ENST00000591470 GCDH Q92947 Glutaryl-CoA dehydrogenase, mitochondrial chr19 GO:0006139 Not Cancer Driver No 57 0.13 37 5 0.135 58
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0006139 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCNA GCNA Q96QF7 Germ cell nuclear acidic protein chrX GO:0006139 Not Cancer Driver No 155 0.224 513 122 0.238 0
GDA_ENST00000358399 GDA Q9Y2T3 Guanine deaminase chr9 GO:0006139 Not Cancer Driver No 86 0.189 22 7 0.318 0
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:0006139 Not Cancer Driver No 109 0.12 339 52 0.153 0
GFPT1 GFPT1 Q06210 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 chr2 GO:0006139 Not Cancer Driver No 81 0.116 75 8 0.107 13
GFPT2 GFPT2 O94808 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 chr5 GO:0006139 Not Cancer Driver No 121 0.177 42 8 0.19 0
GIMAP7 GIMAP7 Q8NHV1 GTPase IMAP family member 7 chr7 GO:0006139 Not Cancer Driver No 90 0.3 11 2 0.182 0
GIN1 GIN1 Q9NXP7 Gypsy retrotransposon integrase-like protein 1 chr5 GO:0006139 Not Cancer Driver No 66 0.126 87 12 0.138 0
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0006139 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0006139 Not Cancer Driver No 36 0.167 14 0 0.0 0
GLRX2_ENST00000367439 GLRX2 Q9NS18 Glutaredoxin-2, mitochondrial chr1 GO:0006139 Not Cancer Driver No 12 0.073 10 1 0.1 0
GLRX_ENST00000505427 GLRX P35754 Glutaredoxin-1 chr5 GO:0006139 Not Cancer Driver No 14 0.132 0 0 0.0 0
GLYAT GLYAT Q6IB77 Glycine N-acyltransferase chr11 GO:0006139 Not Cancer Driver No 75 0.253 9 2 0.222 0
GMDS GMDS O60547 GDP-mannose 4,6 dehydratase chr6 GO:0006139 Not Cancer Driver No 51 0.137 53 6 0.113 0
GMPPB_ENST00000480687 GMPPB Q9Y5P6 Mannose-1-phosphate guanyltransferase beta chr3 GO:0006139 Not Cancer Driver No 39 0.108 10 1 0.1 19
GMPR GMPR P36959 GMP reductase 1 chr6 GO:0006139 Not Cancer Driver No 52 0.151 17 3 0.176 0
GMPR2_ENST00000399440 GMPR2 Q9P2T1 GMP reductase 2 chr14 GO:0006139 Not Cancer Driver No 30 0.086 9 1 0.111 0
GMPS GMPS P49915 GMP synthase [glutamine-hydrolyzing] chr3 GO:0006139 Census, Compendium Yes 88 0.127 76 10 0.132 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0006139 Not Cancer Driver No 42 0.119 11 0 0.0 1
GNMT GNMT Q14749 Glycine N-methyltransferase chr6 GO:0006139 Not Cancer Driver No 25 0.085 0 0 0.0 3
GNPNAT1 GNPNAT1 Q96EK6 Glucosamine 6-phosphate N-acetyltransferase chr14 GO:0006139 Not Cancer Driver No 19 0.103 24 5 0.208 0
GPAT2_ENST00000359548 GPAT2 Q6NUI2 Glycerol-3-phosphate acyltransferase 2, mitochondrial chr2 GO:0006139 Not Cancer Driver No 75 0.094 34 6 0.176 0
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 GO:0006139 Not Cancer Driver No 33 0.104 80 6 0.075 0
GTF2H5 GTF2H5 Q6ZYL4 General transcription factor IIH subunit 5 chr6 GO:0006139 Not Cancer Driver No 7 0.099 0 0 0.0 1
GTF2I GTF2I P78347 General transcription factor II-I chr7 GO:0006139 Compendium Yes 74 0.074 365 27 0.074 0
GTF3A GTF3A Q92664 Transcription factor IIIA chr13 GO:0006139 Not Cancer Driver No 20 0.055 73 7 0.096 0
GTF3C1 GTF3C1 Q12789 General transcription factor 3C polypeptide 1 chr16 GO:0006139 Not Cancer Driver No 323 0.153 735 114 0.155 0
GTF3C2 GTF3C2 Q8WUA4 General transcription factor 3C polypeptide 2 chr2 GO:0006139 Not Cancer Driver No 111 0.122 394 45 0.114 0
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 GO:0006139 Not Cancer Driver No 109 0.123 195 22 0.113 0
GTF3C4 GTF3C4 Q9UKN8 General transcription factor 3C polypeptide 4 chr9 GO:0006139 Not Cancer Driver No 76 0.092 164 13 0.079 0
GTF3C5_ENST00000372097 GTF3C5 Q9Y5Q8 General transcription factor 3C polypeptide 5 chr9 GO:0006139 Not Cancer Driver No 75 0.145 157 21 0.134 0
GTF3C6 GTF3C6 Q969F1 General transcription factor 3C polypeptide 6 chr6 GO:0006139 Not Cancer Driver No 19 0.089 130 11 0.085 0
GTPBP1 GTPBP1 O00178 GTP-binding protein 1 chr22 GO:0006139 Not Cancer Driver No 75 0.112 263 26 0.099 0
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 GO:0006139 Not Cancer Driver No 181 0.262 54 8 0.148 0
GUCY1A2_ENST00000526355 GUCY1A2 P33402 Guanylate cyclase soluble subunit alpha-2 chr11 GO:0006139 Not Cancer Driver No 191 0.261 187 48 0.257 0
GUCY1B1_ENST00000264424 GUCY1B1 Q02153 Guanylate cyclase soluble subunit beta-1 chr4 GO:0006139 Not Cancer Driver No 103 0.166 83 20 0.241 0
GUCY2C GUCY2C P25092 Guanylyl cyclase C chr12 GO:0006139 Not Cancer Driver No 209 0.195 51 7 0.137 2
GUCY2D GUCY2D Q02846 Retinal guanylyl cyclase 1 chr17 GO:0006139 Not Cancer Driver No 138 0.125 205 34 0.166 32
GUCY2F GUCY2F P51841 Retinal guanylyl cyclase 2 chrX GO:0006139 Not Cancer Driver No 230 0.208 88 15 0.17 0
GUK1_ENST00000366718 GUK1 Q16774 Guanylate kinase chr1 GO:0006139 Not Cancer Driver No 28 0.142 71 9 0.127 0
HAAO HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase chr2 GO:0006139 Not Cancer Driver No 40 0.14 30 2 0.067 0
HACD1 HACD1 B0YJ81 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 chr10 GO:0006139 Not Cancer Driver No 74 0.257 63 21 0.333 0
HACD2 HACD2 Q6Y1H2 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 chr3 GO:0006139 Not Cancer Driver No 16 0.063 14 0 0.0 0
HARS2_ENST00000642231 HARS2 P49590 Histidine--tRNA ligase, mitochondrial chr5 GO:0006139 Not Cancer Driver No 48 0.095 34 4 0.118 2
HARS_ENST00000644191 HARS1 P12081 Histidine--tRNA ligase, cytoplasmic chr5 GO:0006139 Not Cancer Driver No 65 0.128 17 2 0.118 7
HELB HELB Q8NG08 DNA helicase B chr12 GO:0006139 Not Cancer Driver No 140 0.129 300 38 0.127 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0006139 Not Cancer Driver No 78 0.093 227 25 0.11 0
HEMK1_ENST00000455834 HEMK1 Q9Y5R4 MTRF1L release factor glutamine methyltransferase chr3 GO:0006139 Not Cancer Driver No 36 0.107 14 0 0.0 0
HENMT1 HENMT1 Q5T8I9 Small RNA 2'-O-methyltransferase chr1 GO:0006139 Not Cancer Driver No 55 0.14 32 6 0.188 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0006139 Not Cancer Driver No 128 0.105 559 51 0.091 0
HIST3H2A H2AW Q7L7L0 Histone H2A type 3 chr1 GO:0006139 Not Cancer Driver No 21 0.162 61 10 0.164 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0006139 Not Cancer Driver No 127 0.138 75 16 0.213 6
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0006139 Not Cancer Driver No 138 0.15 77 7 0.091 0
HK3 HK3 P52790 Hexokinase-3 chr5 GO:0006139 Not Cancer Driver No 164 0.178 71 17 0.239 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0006139 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0006139 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0006139 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMGCR_ENST00000511206 HMGCR P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase chr5 GO:0006139 Not Cancer Driver No 84 0.095 112 12 0.107 0
HMGCS1_ENST00000433297 HMGCS1 Q01581 Hydroxymethylglutaryl-CoA synthase, cytoplasmic chr5 GO:0006139 Not Cancer Driver No 64 0.123 74 10 0.135 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0006139 Not Cancer Driver No 92 0.181 29 4 0.138 19
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0006139 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 GO:0006139 Not Cancer Driver No 31 0.093 202 11 0.054 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0006139 Not Cancer Driver No 22 0.101 3 0 0.0 62
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX GO:0006139 Not Cancer Driver No 27 0.103 15 3 0.2 11
HSD17B12 HSD17B12 Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase chr11 GO:0006139 Not Cancer Driver No 32 0.103 9 0 0.0 0
HSD17B4_ENST00000256216 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 GO:0006139 Not Cancer Driver No 99 0.135 82 12 0.146 4
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0006139 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 GO:0006139 Not Cancer Driver No 52 0.156 23 3 0.13 1
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0006139 Not Cancer Driver No 61 0.106 82 6 0.073 2
HTD2_ENST00000461393 HTD2 P86397 Hydroxyacyl-thioester dehydratase type 2, mitochondrial chr3 GO:0006139 Not Cancer Driver No 1 0.006 0 0 0.0 0
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 GO:0006139 Not Cancer Driver No 130 0.103 28 4 0.143 4
IARS2 IARS2 Q9NSE4 Isoleucine--tRNA ligase, mitochondrial chr1 GO:0006139 Not Cancer Driver No 149 0.147 145 22 0.152 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0006139 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:0006139 Not Cancer Driver No 107 0.109 399 45 0.113 0
ICMT ICMT O60725 Protein-S-isoprenylcysteine O-methyltransferase chr1 GO:0006139 Not Cancer Driver No 24 0.085 0 0 0.0 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0006139 Not Cancer Driver No 82 0.203 41 8 0.195 0
IDO2 IDO2 Q6ZQW0 Indoleamine 2,3-dioxygenase 2 chr8 GO:0006139 Not Cancer Driver No 93 0.221 35 5 0.143 0
IMPDH1_ENST00000626419 IMPDH1 P20839 Inosine-5'-monophosphate dehydrogenase 1 chr7 GO:0006139 Not Cancer Driver No 75 0.146 13 1 0.077 7
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 GO:0006139 Not Cancer Driver No 70 0.136 6 1 0.167 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0006139 Compendium Yes 173 0.111 682 76 0.111 0
INTS1 INTS1 Q8N201 Integrator complex subunit 1 chr7 GO:0006139 Not Cancer Driver No 234 0.107 368 43 0.117 1
ISG20 ISG20 Q96AZ6 Interferon-stimulated gene 20 kDa protein chr15 GO:0006139 Not Cancer Driver No 20 0.11 6 0 0.0 0
ISG20L2 ISG20L2 Q9H9L3 Interferon-stimulated 20 kDa exonuclease-like 2 chr1 GO:0006139 Not Cancer Driver No 46 0.13 232 33 0.142 0
ITPA ITPA Q9BY32 Inosine triphosphate pyrophosphatase chr20 GO:0006139 Not Cancer Driver No 21 0.108 10 1 0.1 1
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0006139 Not Cancer Driver No 51 0.127 133 21 0.158 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0006139 Not Cancer Driver No 88 0.147 160 15 0.094 12
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0006139 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM1B_ENST00000449850 KDM1B Q8NB78 Lysine-specific histone demethylase 1B chr6 GO:0006139 Not Cancer Driver No 81 0.099 74 11 0.149 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 GO:0006139 Not Cancer Driver No 84 0.118 684 81 0.118 0
KIAA0391 PRORP O15091 Mitochondrial ribonuclease P catalytic subunit chr14 GO:0006139 Not Cancer Driver No 62 0.106 60 12 0.2 0
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0006139 Not Cancer Driver No 77 0.158 0 0 0.0 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 GO:0006139 Not Cancer Driver No 233 0.125 1613 198 0.123 4
KRBA2_ENST00000331336 KRBA2 Q6ZNG9 KRAB-A domain-containing protein 2 chr17 GO:0006139 Not Cancer Driver No 56 0.114 150 18 0.12 0
KYNU_ENST00000409512 KYNU Q16719 Kynureninase chr2 GO:0006139 Not Cancer Driver No 103 0.222 20 5 0.25 1
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:0006139 Not Cancer Driver No 58 0.1 350 44 0.126 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0006139 Not Cancer Driver No 133 0.113 97 10 0.103 1
LARS2_ENST00000645846 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 GO:0006139 Not Cancer Driver No 74 0.082 80 8 0.1 3
LCMT2 LCMT2 O60294 tRNA wybutosine-synthesizing protein 4 chr15 GO:0006139 Not Cancer Driver No 101 0.147 33 2 0.061 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0006139 Census Yes 64 0.16 370 57 0.154 0
LIG1 LIG1 P18858 DNA ligase 1 chr19 GO:0006139 Not Cancer Driver No 137 0.149 397 62 0.156 0
LIG3 LIG3 P49916 DNA ligase 3 chr17 GO:0006139 Not Cancer Driver No 125 0.124 280 36 0.129 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0006139 Not Cancer Driver No 134 0.147 63 10 0.159 2
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0006139 Not Cancer Driver No 37 0.177 86 12 0.14 0
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0006139 Not Cancer Driver No 60 0.24 179 32 0.179 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0006139 Not Cancer Driver No 99 0.103 175 15 0.086 10
LRGUK LRGUK Q96M69 Leucine-rich repeat and guanylate kinase domain-containing protein chr7 GO:0006139 Not Cancer Driver No 145 0.176 204 37 0.181 0
LRRC47 LRRC47 Q8N1G4 Leucine-rich repeat-containing protein 47 chr1 GO:0006139 Not Cancer Driver No 65 0.111 291 30 0.103 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0006139 Not Cancer Driver No 519 0.205 90 17 0.189 23
LSM1 LSM1 O15116 U6 snRNA-associated Sm-like protein LSm1 chr8 GO:0006139 Not Cancer Driver No 21 0.158 6 1 0.167 0
LSM10 LSM10 Q969L4 U7 snRNA-associated Sm-like protein LSm10 chr1 GO:0006139 Not Cancer Driver No 21 0.171 12 5 0.417 0
LSM11 LSM11 P83369 U7 snRNA-associated Sm-like protein LSm11 chr5 GO:0006139 Not Cancer Driver No 34 0.094 266 17 0.064 1
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0006139 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAEL MAEL Q96JY0 Protein maelstrom homolog chr1 GO:0006139 Not Cancer Driver No 126 0.29 114 35 0.307 0
MAGI3 MAGI3 Q5TCQ9 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 chr1 GO:0006139 Not Cancer Driver No 154 0.104 1039 105 0.101 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0006139 Census, Compendium Yes 62 0.172 2 0 0.0 7
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0006139 Not Cancer Driver No 91 0.101 151 16 0.106 8
MARS2 MARS2 Q96GW9 Methionine--tRNA ligase, mitochondrial chr2 GO:0006139 Not Cancer Driver No 75 0.126 34 6 0.176 1
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0006139 Not Cancer Driver No 46 0.096 249 22 0.088 0
MBD4 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 GO:0006139 Not Cancer Driver No 61 0.105 268 27 0.101 0
MBLAC1 MBLAC1 A4D2B0 Metallo-beta-lactamase domain-containing protein 1 chr7 GO:0006139 Not Cancer Driver No 26 0.098 175 22 0.126 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0006139 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCCC2 MCCC2 Q9HCC0 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial chr5 GO:0006139 Not Cancer Driver No 60 0.107 25 2 0.08 52
MCEE MCEE Q96PE7 Methylmalonyl-CoA epimerase, mitochondrial chr2 GO:0006139 Not Cancer Driver No 19 0.108 9 0 0.0 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0006139 Not Cancer Driver No 104 0.115 275 38 0.138 1
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 GO:0006139 Not Cancer Driver No 92 0.114 310 47 0.152 0
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 GO:0006139 Not Cancer Driver No 121 0.14 215 35 0.163 0
MCM8_ENST00000378896 MCM8 Q9UJA3 DNA helicase MCM8 chr20 GO:0006139 Not Cancer Driver No 94 0.112 188 19 0.101 1
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 GO:0006139 Not Cancer Driver No 56 0.049 523 13 0.025 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0006139 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MED18_ENST00000398997 MED18 Q9BUE0 Mediator of RNA polymerase II transcription subunit 18 chr1 GO:0006139 Not Cancer Driver No 35 0.168 10 2 0.2 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 GO:0006139 Not Cancer Driver No 76 0.11 446 42 0.094 0
METTL1 METTL1 Q9UBP6 tRNA (guanine-N(7)-)-methyltransferase chr12 GO:0006139 Not Cancer Driver No 43 0.156 89 11 0.124 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0006139 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL16 METTL16 Q86W50 RNA N6-adenosine-methyltransferase METTL16 chr17 GO:0006139 Not Cancer Driver No 55 0.098 172 22 0.128 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0006139 Not Cancer Driver No 74 0.128 274 29 0.106 0
METTL4 METTL4 Q8N3J2 N(6)-adenine-specific methyltransferase METTL4 chr18 GO:0006139 Not Cancer Driver No 61 0.129 34 4 0.118 0
METTL8_ENST00000638989 METTL8 Q9H825 tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial chr2 GO:0006139 Not Cancer Driver No 32 0.11 95 11 0.116 0
MFN1 MFN1 Q8IWA4 Mitofusin-1 chr3 GO:0006139 Not Cancer Driver No 90 0.121 64 5 0.078 0
MGAT1_ENST00000446023 MGAT1 P26572 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase chr5 GO:0006139 Not Cancer Driver No 67 0.151 44 2 0.045 0
MGME1 MGME1 Q9BQP7 Mitochondrial genome maintenance exonuclease 1 chr20 GO:0006139 Not Cancer Driver No 33 0.096 95 7 0.074 1
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0006139 Census Yes 92 0.122 208 22 0.106 85
MLYCD MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0006139 Not Cancer Driver No 41 0.083 82 0 0.0 0
MOCS3 MOCS3 O95396 Adenylyltransferase and sulfurtransferase MOCS3 chr20 GO:0006139 Not Cancer Driver No 61 0.133 15 5 0.333 0
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 GO:0006139 Not Cancer Driver No 300 0.305 252 77 0.306 0
MOV10L1_ENST00000545383 MOV10L1 Q9BXT6 RNA helicase Mov10l1 chr22 GO:0006139 Not Cancer Driver No 184 0.152 178 21 0.118 0
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 GO:0006139 Not Cancer Driver No 13 0.102 0 0 0.0 0
MPG MPG P29372 DNA-3-methyladenine glycosylase chr16 GO:0006139 Not Cancer Driver No 35 0.117 141 21 0.149 0
MPI MPI P34949 Mannose-6-phosphate isomerase chr15 GO:0006139 Not Cancer Driver No 35 0.083 61 10 0.164 13
MPP1 MPP1 Q00013 55 kDa erythrocyte membrane protein chrX GO:0006139 Not Cancer Driver No 79 0.17 194 33 0.17 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0006139 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRM2_ENST00000440306 MRM2 Q9UI43 rRNA methyltransferase 2, mitochondrial chr7 GO:0006139 Not Cancer Driver No 37 0.15 15 1 0.067 1
MRM3 MRM3 Q9HC36 rRNA methyltransferase 3, mitochondrial chr17 GO:0006139 Not Cancer Driver No 45 0.107 83 8 0.096 0
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 GO:0006139 Not Cancer Driver No 37 0.111 45 2 0.044 1
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0006139 Census Yes 92 0.099 37 4 0.108 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0006139 Not Cancer Driver No 100 0.088 211 20 0.095 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0006139 Census Yes 154 0.113 386 41 0.106 6
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 GO:0006139 Not Cancer Driver No 78 0.117 283 32 0.113 0
MTAP MTAP Q13126 S-methyl-5'-thioadenosine phosphorylase chr9 GO:0006139 Not Cancer Driver No 37 0.131 15 0 0.0 0
MTERF1 MTERF1 Q99551 Transcription termination factor 1, mitochondrial chr7 GO:0006139 Not Cancer Driver No 48 0.12 0 0 0.0 0
MTERF2 MTERF2 Q49AM1 Transcription termination factor 2, mitochondrial chr12 GO:0006139 Not Cancer Driver No 49 0.127 0 0 0.0 0
MTFMT MTFMT Q96DP5 Methionyl-tRNA formyltransferase, mitochondrial chr15 GO:0006139 Not Cancer Driver No 35 0.09 56 3 0.054 3
MTO1_ENST00000370300 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 GO:0006139 Not Cancer Driver No 70 0.098 61 2 0.033 1
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0006139 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 GO:0006139 Not Cancer Driver No 73 0.125 136 22 0.162 1
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 GO:0006139 Not Cancer Driver No 117 0.112 160 15 0.094 0
MTRR_ENST00000440940 MTRR Q9UBK8 Methionine synthase reductase chr5 GO:0006139 Not Cancer Driver No 101 0.145 84 13 0.155 5
MUTYH MUTYH Q9UIF7 Adenine DNA glycosylase chr1 GO:0006139 Census Yes 90 0.165 198 29 0.146 23
MVD MVD P53602 Diphosphomevalonate decarboxylase chr16 GO:0006139 Not Cancer Driver No 47 0.117 49 10 0.204 3
MVK MVK Q03426 Mevalonate kinase chr12 GO:0006139 Not Cancer Driver No 50 0.126 25 0 0.0 38
MYBL1 MYBL1 P10243 Myb-related protein A chr8 GO:0006139 Not Cancer Driver No 78 0.104 501 58 0.116 0
N6AMT1 N6AMT1 Q9Y5N5 Methyltransferase N6AMT1 chr21 GO:0006139 Not Cancer Driver No 44 0.206 20 3 0.15 0
NADK2 NADK2 Q4G0N4 NAD kinase 2, mitochondrial chr5 GO:0006139 Not Cancer Driver No 42 0.095 89 3 0.034 0
NADK_ENST00000341991 NADK O95544 NAD kinase chr1 GO:0006139 Not Cancer Driver No 59 0.132 91 18 0.198 0
NADSYN1 NADSYN1 Q6IA69 Glutamine-dependent NAD(+) synthetase chr11 GO:0006139 Not Cancer Driver No 82 0.116 27 8 0.296 3
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0006139 Not Cancer Driver No 61 0.123 386 44 0.114 0
NAMPT NAMPT P43490 Nicotinamide phosphoribosyltransferase chr7 GO:0006139 Not Cancer Driver No 50 0.102 27 5 0.185 0
NANS NANS Q9NR45 Sialic acid synthase chr9 GO:0006139 Not Cancer Driver No 29 0.081 45 1 0.022 6
NAPRT NAPRT Q6XQN6 Nicotinate phosphoribosyltransferase chr8 GO:0006139 Not Cancer Driver No 38 0.071 98 11 0.112 0
NARS NARS1 O43776 Asparagine--tRNA ligase, cytoplasmic chr18 GO:0006139 Not Cancer Driver No 50 0.091 103 16 0.155 4
NARS2 NARS2 Q96I59 Probable asparagine--tRNA ligase, mitochondrial chr11 GO:0006139 Not Cancer Driver No 79 0.166 22 2 0.091 3
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0006139 Not Cancer Driver No 109 0.106 142 18 0.127 0
NAXE NAXE Q8NCW5 NAD(P)H-hydrate epimerase chr1 GO:0006139 Not Cancer Driver No 22 0.076 5 0 0.0 2
NBN NBN O60934 Nibrin chr8 GO:0006139 Census Yes 90 0.119 417 54 0.129 1
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0006139 Not Cancer Driver No 88 0.111 89 8 0.09 0
NCBP3 NCBP3 Q53F19 Nuclear cap-binding protein subunit 3 chr17 GO:0006139 Not Cancer Driver No 52 0.084 507 42 0.083 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0006139 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0006139 Not Cancer Driver No 41 0.105 165 14 0.085 0
NEIL2 NEIL2 Q969S2 Endonuclease 8-like 2 chr8 GO:0006139 Not Cancer Driver No 31 0.093 145 14 0.097 0
NEIL3 NEIL3 Q8TAT5 Endonuclease 8-like 3 chr4 GO:0006139 Not Cancer Driver No 80 0.132 131 18 0.137 0
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0006139 Not Cancer Driver No 35 0.117 83 8 0.096 2
NHP2 NHP2 Q9NX24 H/ACA ribonucleoprotein complex subunit 2 chr5 GO:0006139 Not Cancer Driver No 26 0.17 20 4 0.2 2
NIFK NIFK Q9BYG3 MKI67 FHA domain-interacting nucleolar phosphoprotein chr2 GO:0006139 Not Cancer Driver No 32 0.109 148 15 0.101 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0006139 Compendium Yes 353 0.126 1528 184 0.12 37
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 GO:0006139 Not Cancer Driver No 11 0.072 10 0 0.0 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0006139 Not Cancer Driver No 13 0.086 11 1 0.091 0
NME3 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 GO:0006139 Not Cancer Driver No 10 0.059 4 0 0.0 0
NME4 NME4 O00746 Nucleoside diphosphate kinase, mitochondrial chr16 GO:0006139 Not Cancer Driver No 13 0.07 41 4 0.098 0
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:0006139 Not Cancer Driver No 17 0.08 6 0 0.0 0
NME6_ENST00000415053 NME6 O75414 Nucleoside diphosphate kinase 6 chr3 GO:0006139 Not Cancer Driver No 23 0.124 22 3 0.136 0
NME7 NME7 Q9Y5B8 Nucleoside diphosphate kinase 7 chr1 GO:0006139 Not Cancer Driver No 53 0.141 0 0 0.0 0
NME9_ENST00000333911 NME9 Q86XW9 Thioredoxin domain-containing protein 6 chr3 GO:0006139 Not Cancer Driver No 51 0.155 145 27 0.186 0
NMNAT1 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 GO:0006139 Not Cancer Driver No 39 0.14 49 7 0.143 28
NMNAT2 NMNAT2 Q9BZQ4 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 chr1 GO:0006139 Not Cancer Driver No 54 0.176 22 1 0.045 0
NMNAT3 NMNAT3 Q96T66 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 chr3 GO:0006139 Not Cancer Driver No 32 0.127 53 6 0.113 0
NMRK1_ENST00000361092 NMRK1 Q9NWW6 Nicotinamide riboside kinase 1 chr9 GO:0006139 Not Cancer Driver No 23 0.116 6 0 0.0 0
NMRK2_ENST00000168977 NMRK2 Q9NPI5 Nicotinamide riboside kinase 2 chr19 GO:0006139 Not Cancer Driver No 25 0.109 53 9 0.17 0
NNMT NNMT P40261 Nicotinamide N-methyltransferase chr11 GO:0006139 Not Cancer Driver No 51 0.193 5 1 0.2 0
NOCT NOCT Q9UK39 Nocturnin chr4 GO:0006139 Not Cancer Driver No 33 0.077 89 3 0.034 0
NOL9 NOL9 Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 chr1 GO:0006139 Not Cancer Driver No 73 0.104 102 8 0.078 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 GO:0006139 Not Cancer Driver No 74 0.106 662 69 0.104 0
NOP10 NOP10 Q9NPE3 H/ACA ribonucleoprotein complex subunit 3 chr15 GO:0006139 Not Cancer Driver No 12 0.188 20 2 0.1 1
NOP14 NOP14 P78316 Nucleolar protein 14 chr4 GO:0006139 Not Cancer Driver No 87 0.102 521 46 0.088 0
NOP9 NOP9 Q86U38 Nucleolar protein 9 chr14 GO:0006139 Not Cancer Driver No 53 0.083 166 14 0.084 0
NPM3 NPM3 O75607 Nucleoplasmin-3 chr10 GO:0006139 Not Cancer Driver No 23 0.129 78 11 0.141 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0006139 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPPB NPPB P16860 Natriuretic peptides B chr1 GO:0006139 Not Cancer Driver No 31 0.231 104 28 0.269 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0006139 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0006139 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0006139 Not Cancer Driver No 144 0.138 89 18 0.202 20
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0006139 Not Cancer Driver No 56 0.125 146 13 0.089 0
NSMCE2_ENST00000522563 NSMCE2 Q96MF7 E3 SUMO-protein ligase NSE2 chr8 GO:0006139 Not Cancer Driver No 30 0.121 119 12 0.101 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 GO:0006139 Not Cancer Driver No 112 0.146 221 21 0.095 1
NSUN3 NSUN3 Q9H649 tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial chr3 GO:0006139 Not Cancer Driver No 34 0.1 0 0 0.0 0
NSUN6 NSUN6 Q8TEA1 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 chr10 GO:0006139 Not Cancer Driver No 68 0.145 50 10 0.2 0
NT5C NT5C Q8TCD5 5'(3')-deoxyribonucleotidase, cytosolic type chr17 GO:0006139 Not Cancer Driver No 19 0.095 4 0 0.0 0
NT5C1A NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 GO:0006139 Not Cancer Driver No 86 0.234 95 16 0.168 0
NT5C1B NT5C1B Q96P26 Cytosolic 5'-nucleotidase 1B chr2 GO:0006139 Not Cancer Driver No 136 0.223 253 58 0.229 0
NT5C2_ENST00000404739 NT5C2 P49902 Cytosolic purine 5'-nucleotidase chr10 GO:0006139 Census Yes 57 0.102 85 8 0.094 0
NT5C3A NT5C3A Q9H0P0 Cytosolic 5'-nucleotidase 3A chr7 GO:0006139 Compendium Yes 44 0.131 0 0 0.0 8
NT5C3B NT5C3B Q969T7 7-methylguanosine phosphate-specific 5'-nucleotidase chr17 GO:0006139 Not Cancer Driver No 25 0.083 2 0 0.0 0
NT5E NT5E P21589 5'-nucleotidase chr6 GO:0006139 Not Cancer Driver No 61 0.106 26 2 0.077 1
NT5M NT5M Q9NPB1 5'(3')-deoxyribonucleotidase, mitochondrial chr17 GO:0006139 Not Cancer Driver No 20 0.088 0 0 0.0 0
NTHL1 NTHL1 P78549 Endonuclease III-like protein 1 chr16 GO:0006139 Census Yes 38 0.122 147 18 0.122 0
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0006139 Not Cancer Driver No 30 0.123 243 30 0.123 0
NUDT10_ENST00000356450 NUDT10 Q8NFP7 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha chrX GO:0006139 Not Cancer Driver No 29 0.177 68 8 0.118 0
NUDT11 NUDT11 Q96G61 Diphosphoinositol polyphosphate phosphohydrolase 3-beta chrX GO:0006139 Not Cancer Driver No 30 0.183 65 13 0.2 0
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0006139 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT13 NUDT13 Q86X67 NAD(P)H pyrophosphatase NUDT13, mitochondrial chr10 GO:0006139 Not Cancer Driver No 40 0.114 19 0 0.0 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0006139 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0006139 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0006139 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT17 NUDT17 P0C025 Nucleoside diphosphate-linked moiety X motif 17 chr1 GO:0006139 Not Cancer Driver No 33 0.101 91 15 0.165 0
NUDT18 NUDT18 Q6ZVK8 8-oxo-dGDP phosphatase NUDT18 chr8 GO:0006139 Not Cancer Driver No 22 0.068 39 3 0.077 0
NUDT19 NUDT19 A8MXV4 Acyl-coenzyme A diphosphatase NUDT19 chr19 GO:0006139 Not Cancer Driver No 27 0.072 131 5 0.038 0
NUDT1_ENST00000397046 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0006139 Not Cancer Driver No 25 0.16 17 4 0.235 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 GO:0006139 Not Cancer Driver No 21 0.093 37 3 0.081 0
NUDT2_ENST00000346365 NUDT2 P50583 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] chr9 GO:0006139 Not Cancer Driver No 16 0.109 24 1 0.042 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 GO:0006139 Not Cancer Driver No 22 0.128 38 5 0.132 0
NUDT4B NUDT4B A0A024RBG1 Diphosphoinositol polyphosphate phosphohydrolase NUDT4B chr1 GO:0006139 Not Cancer Driver No 2 0.011 53 0 0.0 0
NUDT4_ENST00000415493 NUDT4 Q9NZJ9 Diphosphoinositol polyphosphate phosphohydrolase 2 chr12 GO:0006139 Not Cancer Driver No 20 0.111 53 9 0.17 0
NUDT5_ENST00000537776 NUDT5 Q9UKK9 ADP-sugar pyrophosphatase chr10 GO:0006139 Not Cancer Driver No 27 0.123 90 11 0.122 0
NUDT7 NUDT7 P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 chr16 GO:0006139 Not Cancer Driver No 45 0.189 42 4 0.095 0
NUDT8 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 GO:0006139 Not Cancer Driver No 22 0.093 69 10 0.145 0
NUDT9 NUDT9 Q9BW91 ADP-ribose pyrophosphatase, mitochondrial chr4 GO:0006139 Not Cancer Driver No 27 0.077 177 16 0.09 0
NYNRIN NYNRIN Q9P2P1 Protein NYNRIN chr14 GO:0006139 Not Cancer Driver No 250 0.132 636 70 0.11 0
OAS2 OAS2 P29728 2'-5'-oligoadenylate synthase 2 chr12 GO:0006139 Not Cancer Driver No 141 0.196 47 14 0.298 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0006139 Not Cancer Driver No 139 0.128 147 17 0.116 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 GO:0006139 Not Cancer Driver No 150 0.147 106 19 0.179 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0006139 Not Cancer Driver No 37 0.107 71 12 0.169 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0006139 Not Cancer Driver No 114 0.119 131 17 0.13 60
OSGEP OSGEP Q9NPF4 tRNA N6-adenosine threonylcarbamoyltransferase chr14 GO:0006139 Not Cancer Driver No 46 0.137 32 4 0.125 14
OSGEPL1_ENST00000522700 OSGEPL1 Q9H4B0 tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial chr2 GO:0006139 Not Cancer Driver No 43 0.104 1 0 0.0 0
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 GO:0006139 Not Cancer Driver No 23 0.054 35 3 0.086 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 GO:0006139 Not Cancer Driver No 139 0.116 78 10 0.128 0
PAN3 PAN3 Q58A45 PAN2-PAN3 deadenylation complex subunit PAN3 chr13 GO:0006139 Not Cancer Driver No 104 0.117 323 35 0.108 0
PANK1 PANK1 Q8TE04 Pantothenate kinase 1 chr10 GO:0006139 Not Cancer Driver No 62 0.104 248 17 0.069 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 GO:0006139 Not Cancer Driver No 46 0.081 206 14 0.068 30
PANK3 PANK3 Q9H999 Pantothenate kinase 3 chr5 GO:0006139 Not Cancer Driver No 41 0.111 0 0 0.0 0
PANK4 PANK4 Q9NVE7 4'-phosphopantetheine phosphatase chr1 GO:0006139 Not Cancer Driver No 92 0.119 71 15 0.211 0
PAPOLA PAPOLA P51003 Poly(A) polymerase alpha chr14 GO:0006139 Not Cancer Driver No 97 0.13 293 28 0.096 0
PAPOLG PAPOLG Q9BWT3 Poly(A) polymerase gamma chr2 GO:0006139 Not Cancer Driver No 94 0.128 303 35 0.116 0
PAPSS1 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 GO:0006139 Not Cancer Driver No 94 0.151 82 14 0.171 0
PAPSS2_ENST00000361175 PAPSS2 O95340 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 chr10 GO:0006139 Not Cancer Driver No 81 0.132 100 7 0.07 4
PARG_ENST00000616448 PARG Q86W56 Poly(ADP-ribose) glycohydrolase chr10 GO:0006139 Not Cancer Driver No 60 0.061 519 1 0.002 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0006139 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0006139 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0006139 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP10_ENST00000313028 PARP10 Q53GL7 Protein mono-ADP-ribosyltransferase PARP10 chr8 GO:0006139 Not Cancer Driver No 122 0.119 552 68 0.123 0
PARP16 PARP16 Q8N5Y8 Protein mono-ADP-ribosyltransferase PARP16 chr15 GO:0006139 Not Cancer Driver No 37 0.115 33 3 0.091 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 GO:0006139 Not Cancer Driver No 74 0.127 172 23 0.134 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0006139 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0006139 Not Cancer Driver No 110 0.129 45 3 0.067 0
PARS2 PARS2 Q7L3T8 Probable proline--tRNA ligase, mitochondrial chr1 GO:0006139 Not Cancer Driver No 50 0.105 8 2 0.25 0
PCF11 PCF11 O94913 Pre-mRNA cleavage complex 2 protein Pcf11 chr11 GO:0006139 Not Cancer Driver No 211 0.136 1250 189 0.151 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0006139 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCIF1 PCIF1 Q9H4Z3 mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase chr20 GO:0006139 Not Cancer Driver No 77 0.109 288 37 0.128 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0006139 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:0006139 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0006139 Not Cancer Driver No 59 0.097 129 8 0.062 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0006139 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE4A PDE4A P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A chr19 GO:0006139 Not Cancer Driver No 123 0.139 559 67 0.12 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0006139 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE4C PDE4C Q08493 cAMP-specific 3',5'-cyclic phosphodiesterase 4C chr19 GO:0006139 Not Cancer Driver No 122 0.171 362 61 0.169 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0006139 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:0006139 Not Cancer Driver No 113 0.129 163 23 0.141 0
PDE7A PDE7A Q13946 High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A chr8 GO:0006139 Not Cancer Driver No 49 0.102 30 7 0.233 0
PDE7B PDE7B Q9NP56 cAMP-specific 3',5'-cyclic phosphodiesterase 7B chr6 GO:0006139 Not Cancer Driver No 74 0.164 47 7 0.149 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0006139 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDE8B PDE8B O95263 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B chr5 GO:0006139 Not Cancer Driver No 144 0.163 208 19 0.091 1
PDE9A PDE9A O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A chr21 GO:0006139 Not Cancer Driver No 91 0.153 160 34 0.212 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX GO:0006139 Not Cancer Driver No 70 0.179 43 6 0.14 20
PDHA2 PDHA2 P29803 Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial chr4 GO:0006139 Not Cancer Driver No 163 0.42 41 17 0.415 0
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 GO:0006139 Not Cancer Driver No 32 0.089 4 0 0.0 2
PDHX PDHX O00330 Pyruvate dehydrogenase protein X component, mitochondrial chr11 GO:0006139 Not Cancer Driver No 62 0.124 179 28 0.156 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 GO:0006139 Not Cancer Driver No 38 0.099 67 10 0.149 0
PFAS PFAS O15067 Phosphoribosylformylglycinamidine synthase chr17 GO:0006139 Not Cancer Driver No 157 0.117 380 36 0.095 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:0006139 Not Cancer Driver No 91 0.117 29 4 0.138 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0006139 Not Cancer Driver No 80 0.103 70 8 0.114 9
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 GO:0006139 Not Cancer Driver No 133 0.17 43 10 0.233 0
PGBD5 PGBD5 Q8N414 PiggyBac transposable element-derived protein 5 chr1 GO:0006139 Not Cancer Driver No 73 0.139 126 1 0.008 0
PGM2 PGM2 Q96G03 Phosphopentomutase chr4 GO:0006139 Not Cancer Driver No 79 0.129 108 13 0.12 0
PGM3_ENST00000513973 PGM3 O95394 Phosphoacetylglucosamine mutase chr6 GO:0006139 Not Cancer Driver No 78 0.144 77 8 0.104 7
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0006139 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIPOX PIPOX Q9P0Z9 Peroxisomal sarcosine oxidase chr17 GO:0006139 Not Cancer Driver No 52 0.133 21 3 0.143 0
PIWIL1 PIWIL1 Q96J94 Piwi-like protein 1 chr12 GO:0006139 Not Cancer Driver No 202 0.235 172 37 0.215 0
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0006139 Not Cancer Driver No 138 0.142 232 38 0.164 0
PIWIL4 PIWIL4 Q7Z3Z4 Piwi-like protein 4 chr11 GO:0006139 Not Cancer Driver No 115 0.135 89 11 0.124 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 GO:0006139 Not Cancer Driver No 27 0.107 24 6 0.25 0
PMM1 PMM1 Q92871 Phosphomannomutase 1 chr22 GO:0006139 Not Cancer Driver No 37 0.141 15 0 0.0 0
PMM2 PMM2 O15305 Phosphomannomutase 2 chr16 GO:0006139 Not Cancer Driver No 25 0.102 16 1 0.062 66
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 GO:0006139 Not Cancer Driver No 38 0.198 3 0 0.0 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0006139 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNLDC1_ENST00000610273 PNLDC1 Q8NA58 Poly(A)-specific ribonuclease PNLDC1 chr6 GO:0006139 Not Cancer Driver No 105 0.202 6 0 0.0 1
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0006139 Not Cancer Driver No 38 0.131 29 2 0.069 5
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0006139 Not Cancer Driver No 86 0.11 115 10 0.087 2
PNRC2_ENST00000374468 PNRC2 Q9NPJ4 Proline-rich nuclear receptor coactivator 2 chr1 GO:0006139 Not Cancer Driver No 1 0.007 122 1 0.008 0
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX GO:0006139 Not Cancer Driver No 185 0.127 347 45 0.13 3
POLA2 POLA2 Q14181 DNA polymerase alpha subunit B chr11 GO:0006139 Not Cancer Driver No 63 0.105 102 16 0.157 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0006139 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0006139 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLD2_ENST00000452185 POLD2 P49005 DNA polymerase delta subunit 2 chr7 GO:0006139 Not Cancer Driver No 49 0.104 65 3 0.046 0
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 GO:0006139 Not Cancer Driver No 51 0.109 326 39 0.12 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0006139 Not Cancer Driver No 36 0.098 94 13 0.138 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 GO:0006139 Census, Compendium Yes 409 0.179 239 44 0.184 3
POLE2 POLE2 P56282 DNA polymerase epsilon subunit 2 chr14 GO:0006139 Not Cancer Driver No 53 0.101 32 2 0.062 0
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 GO:0006139 Not Cancer Driver No 11 0.075 117 9 0.077 0
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0006139 Not Cancer Driver No 64 0.132 46 4 0.087 3
POLG_ENST00000442287 POLG P54098 DNA polymerase subunit gamma-1 chr15 GO:0006139 Census Yes 139 0.112 421 42 0.1 73
POLH POLH Q9Y253 DNA polymerase eta chr6 GO:0006139 Not Cancer Driver No 72 0.101 291 20 0.069 10
POLI POLI Q9UNA4 DNA polymerase iota chr18 GO:0006139 Not Cancer Driver No 82 0.111 300 32 0.107 0
POLK POLK Q9UBT6 DNA polymerase kappa chr5 GO:0006139 Not Cancer Driver No 97 0.111 293 36 0.123 0
POLL_ENST00000370169 POLL Q9UGP5 DNA polymerase lambda chr10 GO:0006139 Not Cancer Driver No 69 0.12 215 16 0.074 0
POLQ POLQ O75417 DNA polymerase theta chr3 GO:0006139 Census, Compendium Yes 364 0.141 949 135 0.142 0
POLR1B_ENST00000263331 POLR1B Q9H9Y6 DNA-directed RNA polymerase I subunit RPA2 chr2 GO:0006139 Not Cancer Driver No 120 0.106 69 10 0.145 2
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 GO:0006139 Not Cancer Driver No 39 0.093 85 6 0.071 0
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 GO:0006139 Not Cancer Driver No 15 0.087 15 1 0.067 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 GO:0006139 Not Cancer Driver No 21 0.168 22 5 0.227 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 GO:0006139 Not Cancer Driver No 10 0.149 0 0 0.0 0
POLR3H_ENST00000396504 POLR3H Q9Y535 DNA-directed RNA polymerase III subunit RPC8 chr22 GO:0006139 Not Cancer Driver No 23 0.113 33 6 0.182 0
POLR3K POLR3K Q9Y2Y1 DNA-directed RNA polymerase III subunit RPC10 chr16 GO:0006139 Not Cancer Driver No 10 0.093 0 0 0.0 1
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 GO:0006139 Not Cancer Driver No 161 0.157 495 75 0.152 3
POP4 POP4 O95707 Ribonuclease P protein subunit p29 chr19 GO:0006139 Not Cancer Driver No 25 0.114 53 9 0.17 0
POP5 POP5 Q969H6 Ribonuclease P/MRP protein subunit POP5 chr12 GO:0006139 Not Cancer Driver No 17 0.104 9 2 0.222 0
POP7 POP7 O75817 Ribonuclease P protein subunit p20 chr7 GO:0006139 Not Cancer Driver No 20 0.143 59 13 0.22 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0006139 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0006139 Census Yes 72 0.143 44 4 0.091 3
PPAT PPAT Q06203 Amidophosphoribosyltransferase chr4 GO:0006139 Not Cancer Driver No 66 0.128 48 4 0.083 0
PPCDC PPCDC Q96CD2 Phosphopantothenoylcysteine decarboxylase chr15 GO:0006139 Not Cancer Driver No 13 0.064 6 0 0.0 0
PPCS PPCS Q9HAB8 Phosphopantothenate--cysteine ligase chr1 GO:0006139 Not Cancer Driver No 39 0.125 13 0 0.0 2
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 GO:0006139 Census, Compendium Yes 54 0.089 370 32 0.086 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0006139 Not Cancer Driver No 37 0.121 0 0 0.0 23
PPT2_ENST00000395523 PPT2 Q9UMR5 Lysosomal thioesterase PPT2 chr6 GO:0006139 Compendium Yes 45 0.149 0 0 0.0 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0006139 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRIM1 PRIM1 P49642 DNA primase small subunit chr12 GO:0006139 Not Cancer Driver No 31 0.074 22 1 0.045 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0006139 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRIMPOL_ENST00000503752 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 GO:0006139 Not Cancer Driver No 50 0.089 92 7 0.076 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0006139 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:0006139 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0006139 Not Cancer Driver No 83 0.13 72 6 0.083 0
PRMT7_ENST00000441236 PRMT7 Q9NVM4 Protein arginine N-methyltransferase 7 chr16 GO:0006139 Not Cancer Driver No 71 0.103 39 1 0.026 3
PRPF18 PRPF18 Q99633 Pre-mRNA-splicing factor 18 chr10 GO:0006139 Not Cancer Driver No 52 0.152 93 18 0.194 0
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX GO:0006139 Not Cancer Driver No 50 0.157 0 0 0.0 14
PRPS1L1_ENST00000638645 PRPS1L1 P21108 Ribose-phosphate pyrophosphokinase 3 chr7 GO:0006139 Not Cancer Driver No 83 0.261 0 0 0.0 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX GO:0006139 Not Cancer Driver No 56 0.176 4 1 0.25 0
PRPSAP2 PRPSAP2 O60256 Phosphoribosyl pyrophosphate synthase-associated protein 2 chr17 GO:0006139 Not Cancer Driver No 54 0.146 19 3 0.158 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0006139 Census, Compendium Yes 69 0.282 205 49 0.239 1
PRTFDC1 PRTFDC1 Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 chr10 GO:0006139 Not Cancer Driver No 29 0.129 3 0 0.0 0
PSMC3IP PSMC3IP Q9P2W1 Homologous-pairing protein 2 homolog chr17 GO:0006139 Not Cancer Driver No 25 0.115 73 8 0.11 0
PSTK PSTK Q8IV42 L-seryl-tRNA(Sec) kinase chr10 GO:0006139 Not Cancer Driver No 48 0.138 79 15 0.19 0
PTCD1 PTCD1 O75127 Pentatricopeptide repeat-containing protein 1, mitochondrial chr7 GO:0006139 Not Cancer Driver No 99 0.141 224 42 0.188 0
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0006139 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0006139 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0006139 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTHLH_ENST00000539239 PTHLH P12272 Parathyroid hormone-related protein chr12 GO:0006139 Not Cancer Driver No 44 0.249 132 40 0.303 2
PUS1 PUS1 Q9Y606 Pseudouridylate synthase 1 homolog chr12 GO:0006139 Not Cancer Driver No 48 0.112 157 18 0.115 1
PUS10_ENST00000407787 PUS10 Q3MIT2 tRNA pseudouridine synthase Pus10 chr2 GO:0006139 Not Cancer Driver No 59 0.112 43 5 0.116 0
PUS3_ENST00000530811 PUS3 Q9BZE2 tRNA pseudouridine(38/39) synthase chr11 GO:0006139 Not Cancer Driver No 55 0.114 150 15 0.1 0
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 GO:0006139 Not Cancer Driver No 73 0.11 162 17 0.105 1
PUSL1 PUSL1 Q8N0Z8 tRNA pseudouridine synthase-like 1 chr1 GO:0006139 Not Cancer Driver No 15 0.05 76 1 0.013 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:0006139 Not Cancer Driver No 101 0.13 106 16 0.151 4
QPRT QPRT Q15274 Nicotinate-nucleotide pyrophosphorylase [carboxylating] chr16 GO:0006139 Not Cancer Driver No 29 0.098 7 1 0.143 0
QRSL1 QRSL1 Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial chr6 GO:0006139 Not Cancer Driver No 63 0.119 63 4 0.063 2
QTRT1 QTRT1 Q9BXR0 Queuine tRNA-ribosyltransferase catalytic subunit 1 chr19 GO:0006139 Not Cancer Driver No 55 0.136 36 9 0.25 0
QTRT2_ENST00000281273 QTRT2 Q9H974 Queuine tRNA-ribosyltransferase accessory subunit 2 chr3 GO:0006139 Not Cancer Driver No 51 0.123 30 6 0.2 0
RAB23_ENST00000317483 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 GO:0006139 Not Cancer Driver No 28 0.118 62 6 0.097 2
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0006139 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAD21L1 RAD21L1 Q9H4I0 Double-strand-break repair protein rad21-like protein 1 chr20 GO:0006139 Not Cancer Driver No 37 0.067 186 5 0.027 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0006139 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:0006139 Not Cancer Driver No 47 0.125 18 2 0.111 6
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 GO:0006139 Not Cancer Driver No 34 0.104 49 10 0.204 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0006139 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 GO:0006139 Not Cancer Driver No 41 0.098 251 30 0.12 0
RAD54L_ENST00000442598 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0006139 Not Cancer Driver No 79 0.106 124 13 0.105 0
RAMAC RAMAC Q9BTL3 RNA guanine-N7 methyltransferase activating subunit chr15 GO:0006139 Not Cancer Driver No 14 0.119 118 14 0.119 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0006139 Not Cancer Driver No 20 0.093 14 1 0.071 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0006139 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARS RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 GO:0006139 Not Cancer Driver No 72 0.109 41 3 0.073 2
RARS2 RARS2 Q5T160 Probable arginine--tRNA ligase, mitochondrial chr6 GO:0006139 Not Cancer Driver No 88 0.152 20 1 0.05 0
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0006139 Not Cancer Driver No 99 0.11 750 76 0.101 1
RBM47_ENST00000295971 RBM47 A0AV96 RNA-binding protein 47 chr4 GO:0006139 Not Cancer Driver No 143 0.241 131 28 0.214 0
RBM7_ENST00000540163 RBM7 Q9Y580 RNA-binding protein 7 chr11 GO:0006139 Not Cancer Driver No 36 0.135 194 27 0.139 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0006139 Not Cancer Driver No 33 0.126 23 0 0.0 0
RCL1 RCL1 Q9Y2P8 RNA 3'-terminal phosphate cyclase-like protein chr9 GO:0006139 Not Cancer Driver No 40 0.107 12 0 0.0 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:0006139 Not Cancer Driver No 60 0.11 244 26 0.107 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 GO:0006139 Census, Compendium Yes 138 0.114 608 71 0.117 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0006139 Not Cancer Driver No 132 0.133 495 71 0.143 0
REV1 REV1 Q9UBZ9 DNA repair protein REV1 chr2 GO:0006139 Not Cancer Driver No 122 0.098 660 67 0.102 0
REV3L_ENST00000368802 REV3L O60673 DNA polymerase zeta catalytic subunit chr6 GO:0006139 Not Cancer Driver No 379 0.121 1665 211 0.127 0
REXO2 REXO2 Q9Y3B8 Oligoribonuclease, mitochondrial chr11 GO:0006139 Not Cancer Driver No 19 0.08 43 4 0.093 0
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 GO:0006139 Not Cancer Driver No 34 0.081 298 26 0.087 0
RFK RFK Q969G6 Riboflavin kinase chr9 GO:0006139 Not Cancer Driver No 15 0.097 1 0 0.0 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0006139 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 GO:0006139 Not Cancer Driver No 25 0.122 0 0 0.0 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0006139 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RMI1 RMI1 Q9H9A7 RecQ-mediated genome instability protein 1 chr9 GO:0006139 Not Cancer Driver No 67 0.107 243 26 0.107 0
RMI2 RMI2 Q96E14 RecQ-mediated genome instability protein 2 chr16 GO:0006139 Census Yes 12 0.082 86 5 0.058 0
RNASE4_ENST00000555597 RNASE4 P34096 Ribonuclease 4 chr14 GO:0006139 Not Cancer Driver No 24 0.163 9 2 0.222 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 GO:0006139 Not Cancer Driver No 33 0.115 124 20 0.161 2
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 GO:0006139 Not Cancer Driver No 42 0.14 31 3 0.097 7
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0006139 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF113A RNF113A O15541 E3 ubiquitin-protein ligase RNF113A chrX GO:0006139 Not Cancer Driver No 61 0.178 226 51 0.226 0
RNF113B RNF113B Q8IZP6 RING finger protein 113B chr13 GO:0006139 Not Cancer Driver No 56 0.174 170 34 0.2 0
RNF138 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 GO:0006139 Not Cancer Driver No 44 0.18 34 6 0.176 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0006139 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF212 RNF212 Q495C1 Probable E3 SUMO-protein ligase RNF212 chr4 GO:0006139 Not Cancer Driver No 36 0.121 58 12 0.207 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0006139 Not Cancer Driver No 56 0.115 226 29 0.128 0
RNGTT RNGTT O60942 mRNA-capping enzyme chr6 GO:0006139 Not Cancer Driver No 69 0.116 112 12 0.107 0
RNMT_ENST00000543302 RNMT O43148 mRNA cap guanine-N7 methyltransferase chr18 GO:0006139 Not Cancer Driver No 67 0.141 159 23 0.145 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0006139 Not Cancer Driver No 57 0.109 182 17 0.093 4
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 GO:0006139 Not Cancer Driver No 56 0.092 293 25 0.085 0
RPP14_ENST00000295959 RPP14 O95059 Ribonuclease P protein subunit p14 chr3 GO:0006139 Not Cancer Driver No 8 0.065 0 0 0.0 0
RPP21_ENST00000442966 RPP21 Q9H633 Ribonuclease P protein subunit p21 chr6 GO:0006139 Not Cancer Driver No 16 0.104 51 4 0.078 0
RPP25 RPP25 Q9BUL9 Ribonuclease P protein subunit p25 chr15 GO:0006139 Not Cancer Driver No 11 0.055 162 11 0.068 0
RPP25L RPP25L Q8N5L8 Ribonuclease P protein subunit p25-like protein chr9 GO:0006139 Not Cancer Driver No 31 0.19 113 18 0.159 0
RPP30_ENST00000371703 RPP30 P78346 Ribonuclease P protein subunit p30 chr10 GO:0006139 Not Cancer Driver No 28 0.104 21 2 0.095 0
RPP38_ENST00000378202 RPP38 P78345 Ribonuclease P protein subunit p38 chr10 GO:0006139 Not Cancer Driver No 36 0.127 118 19 0.161 0
RPP40 RPP40 O75818 Ribonuclease P protein subunit p40 chr6 GO:0006139 Not Cancer Driver No 51 0.14 5 0 0.0 0
RPS21 RPS21 P63220 40S ribosomal protein S21 chr20 GO:0006139 Not Cancer Driver No 8 0.096 0 0 0.0 0
RPUSD1_ENST00000007264 RPUSD1 Q9UJJ7 RNA pseudouridylate synthase domain-containing protein 1 chr16 GO:0006139 Not Cancer Driver No 30 0.096 88 3 0.034 0
RPUSD2 RPUSD2 Q8IZ73 Pseudouridylate synthase RPUSD2 chr15 GO:0006139 Not Cancer Driver No 49 0.09 231 22 0.095 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 GO:0006139 Not Cancer Driver No 33 0.094 85 5 0.059 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:0006139 Not Cancer Driver No 54 0.143 97 15 0.155 0
RRM1 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 GO:0006139 Not Cancer Driver No 74 0.093 41 7 0.171 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0006139 Not Cancer Driver No 46 0.131 32 5 0.156 9
RRM2_ENST00000641198 RRM2 P31350 Ribonucleoside-diphosphate reductase subunit M2 chr2 GO:0006139 Not Cancer Driver No 40 0.103 48 0 0.0 0
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0006139 Not Cancer Driver No 66 0.101 115 15 0.13 0
RTCB RTCB Q9Y3I0 RNA-splicing ligase RtcB homolog chr22 GO:0006139 Not Cancer Driver No 57 0.113 74 7 0.095 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0006139 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTF2_ENST00000357348 RTF2 Q9BY42 Replication termination factor 2 chr20 GO:0006139 Not Cancer Driver No 44 0.144 170 22 0.129 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0006139 Compendium Yes 90 0.195 184 26 0.141 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0006139 Not Cancer Driver No 104 0.166 91 14 0.154 13
SARM1 SARM1 Q6SZW1 NAD(+) hydrolase SARM1 chr17 GO:0006139 Not Cancer Driver No 36 0.05 80 4 0.05 0
SARS2_ENST00000221431 SARS2 Q9NP81 Serine--tRNA ligase, mitochondrial chr19 GO:0006139 Not Cancer Driver No 64 0.124 111 14 0.126 1
SARS_ENST00000234677 SARS1 P49591 Serine--tRNA ligase, cytoplasmic chr1 GO:0006139 Not Cancer Driver No 56 0.109 83 4 0.048 1
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:0006139 Not Cancer Driver No 71 0.089 685 63 0.092 0
SCAF8_ENST00000367178 SCAF8 Q9UPN6 SR-related and CTD-associated factor 8 chr6 GO:0006139 Not Cancer Driver No 155 0.122 939 118 0.126 0
SEPSECS SEPSECS Q9HD40 O-phosphoseryl-tRNA(Sec) selenium transferase chr4 GO:0006139 Not Cancer Driver No 47 0.094 22 7 0.318 3
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0006139 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0006139 Not Cancer Driver No 62 0.091 154 12 0.078 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0006139 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 GO:0006139 Not Cancer Driver No 51 0.106 32 7 0.219 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0006139 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0006139 Not Cancer Driver No 48 0.12 163 15 0.092 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 GO:0006139 Not Cancer Driver No 140 0.112 390 54 0.138 1
SLBP SLBP Q14493 Histone RNA hairpin-binding protein chr4 GO:0006139 Not Cancer Driver No 21 0.078 236 17 0.072 0
SLC22A13 SLC22A13 Q9Y226 Solute carrier family 22 member 13 chr3 GO:0006139 Not Cancer Driver No 55 0.1 32 3 0.094 0
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 GO:0006139 Not Cancer Driver No 22 0.071 34 2 0.059 17
SLC25A16 SLC25A16 P16260 Graves disease carrier protein chr10 GO:0006139 Not Cancer Driver No 37 0.111 9 0 0.0 0
SLC26A1 SLC26A1 Q9H2B4 Sulfate anion transporter 1 chr4 GO:0006139 Not Cancer Driver No 54 0.077 86 7 0.081 2
SLC26A2 SLC26A2 P50443 Sulfate transporter chr5 GO:0006139 Not Cancer Driver No 71 0.096 41 3 0.073 9
SLC28A1_ENST00000286749 SLC28A1 O00337 Sodium/nucleoside cotransporter 1 chr15 GO:0006139 Not Cancer Driver No 121 0.186 15 7 0.467 3
SLC28A2 SLC28A2 O43868 Sodium/nucleoside cotransporter 2 chr15 GO:0006139 Not Cancer Driver No 93 0.141 36 6 0.167 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0006139 Not Cancer Driver No 51 0.112 27 4 0.148 0
SLC35B2 SLC35B2 Q8TB61 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 chr6 GO:0006139 Not Cancer Driver No 49 0.113 13 3 0.231 0
SLC35B3 SLC35B3 Q9H1N7 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 chr6 GO:0006139 Not Cancer Driver No 33 0.082 6 0 0.0 0
SLC5A8 SLC5A8 Q8N695 Sodium-coupled monocarboxylate transporter 1 chr12 GO:0006139 Not Cancer Driver No 156 0.256 33 10 0.303 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:0006139 Not Cancer Driver No 177 0.196 34 8 0.235 0
SLFN13 SLFN13 Q68D06 Schlafen family member 13 chr17 GO:0006139 Not Cancer Driver No 152 0.169 45 5 0.111 0
SLFN14 SLFN14 P0C7P3 Protein SLFN14 chr17 GO:0006139 Not Cancer Driver No 66 0.072 61 3 0.049 4
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0006139 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0006139 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0006139 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0006139 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0006139 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0006139 Not Cancer Driver No 128 0.134 335 49 0.146 11
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0006139 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0006139 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0006139 Not Cancer Driver No 128 0.117 458 57 0.124 0
SMN2_ENST00000380741 SMN2 Q16637 Survival motor neuron protein chr5 GO:0006139 Not Cancer Driver No 1 0.003 220 1 0.005 18
SMUG1 SMUG1 Q53HV7 Single-strand selective monofunctional uracil DNA glycosylase chr12 GO:0006139 Not Cancer Driver No 33 0.122 46 2 0.043 0
SNAPC1 SNAPC1 Q16533 snRNA-activating protein complex subunit 1 chr14 GO:0006139 Not Cancer Driver No 36 0.098 158 16 0.101 0
SNAPC2 SNAPC2 Q13487 snRNA-activating protein complex subunit 2 chr19 GO:0006139 Not Cancer Driver No 33 0.099 260 24 0.092 0
SNAPC3_ENST00000610884 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 GO:0006139 Not Cancer Driver No 30 0.073 99 2 0.02 0
SNAPC4 SNAPC4 Q5SXM2 snRNA-activating protein complex subunit 4 chr9 GO:0006139 Not Cancer Driver No 143 0.097 1094 96 0.088 0
SNAPC5_ENST00000395589 SNAPC5 O75971 snRNA-activating protein complex subunit 5 chr15 GO:0006139 Not Cancer Driver No 9 0.092 95 9 0.095 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 GO:0006139 Census Yes 127 0.14 258 48 0.186 0
SPATA22_ENST00000397168 SPATA22 Q8NHS9 Spermatogenesis-associated protein 22 chr17 GO:0006139 Not Cancer Driver No 71 0.196 220 40 0.182 0
SPIN1 SPIN1 Q9Y657 Spindlin-1 chr9 GO:0006139 Not Cancer Driver No 31 0.118 132 18 0.136 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0006139 Not Cancer Driver No 59 0.149 26 5 0.192 0
SPOCD1 SPOCD1 Q6ZMY3 SPOC domain-containing protein 1 chr1 GO:0006139 Not Cancer Driver No 158 0.13 877 113 0.129 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0006139 Not Cancer Driver No 73 0.149 252 38 0.151 1
SRBD1 SRBD1 Q8N5C6 S1 RNA-binding domain-containing protein 1 chr2 GO:0006139 Not Cancer Driver No 110 0.111 279 29 0.104 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0006139 Not Cancer Driver No 127 0.111 528 64 0.121 4
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 GO:0006139 Not Cancer Driver No 78 0.113 343 46 0.134 0
SRRT SRRT Q9BXP5 Serrate RNA effector molecule homolog chr7 GO:0006139 Not Cancer Driver No 146 0.167 595 108 0.182 0
SSB SSB P05455 Lupus La protein chr2 GO:0006139 Not Cancer Driver No 39 0.096 181 18 0.099 0
SSU72 SSU72 Q9NP77 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr1 GO:0006139 Not Cancer Driver No 18 0.093 65 3 0.046 0
SSU72P2 SSU72P2 A0A1W2PQD8 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0006139 Not Cancer Driver No 3 0.015 15 0 0.0 0
SSU72P3 SSU72P3 A0A1W2PQJ5 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0006139 Not Cancer Driver No 2 0.01 17 0 0.0 0
SSU72P8 SSU72P8 A0A1W2PR75 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr7 GO:0006139 Not Cancer Driver No 8 0.041 8 0 0.0 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0006139 Census, Compendium Yes 110 0.143 152 15 0.099 19
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0006139 Not Cancer Driver No 40 0.112 117 9 0.077 0
STPG4 STPG4 Q8N801 Protein STPG4 chr2 GO:0006139 Not Cancer Driver No 32 0.129 132 17 0.129 0
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 GO:0006139 Not Cancer Driver No 13 0.102 108 6 0.056 0
SUCLA2 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 GO:0006139 Not Cancer Driver No 51 0.11 46 6 0.13 3
SUCLG2_ENST00000307227 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 GO:0006139 Not Cancer Driver No 48 0.111 12 2 0.167 0
SULT1A1_ENST00000314752 SULT1A1 P50225 Sulfotransferase 1A1 chr16 GO:0006139 Not Cancer Driver No 69 0.234 14 3 0.214 0
SULT1A2 SULT1A2 P50226 Sulfotransferase 1A2 chr16 GO:0006139 Not Cancer Driver No 46 0.156 3 0 0.0 0
SULT1B1 SULT1B1 O43704 Sulfotransferase 1B1 chr4 GO:0006139 Not Cancer Driver No 82 0.277 15 7 0.467 0
SULT1C3 SULT1C3 Q6IMI6 Sulfotransferase 1C3 chr2 GO:0006139 Not Cancer Driver No 77 0.253 14 5 0.357 0
SULT1C4 SULT1C4 O75897 Sulfotransferase 1C4 chr2 GO:0006139 Not Cancer Driver No 57 0.189 19 5 0.263 0
SULT1E1 SULT1E1 P49888 Sulfotransferase 1E1 chr4 GO:0006139 Not Cancer Driver No 76 0.259 15 5 0.333 0
SULT2A1 SULT2A1 Q06520 Sulfotransferase 2A1 chr19 GO:0006139 Not Cancer Driver No 50 0.175 0 0 0.0 0
SULT2B1 SULT2B1 O00204 Sulfotransferase 2B1 chr19 GO:0006139 Not Cancer Driver No 42 0.115 100 11 0.11 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 GO:0006139 Not Cancer Driver No 222 0.129 761 107 0.141 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0006139 Not Cancer Driver No 72 0.092 140 12 0.086 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0006139 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYCP1_ENST00000618516 SYCP1 Q15431 Synaptonemal complex protein 1 chr1 GO:0006139 Not Cancer Driver No 207 0.212 602 124 0.206 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:0006139 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAF11 TAF11 Q15544 Transcription initiation factor TFIID subunit 11 chr6 GO:0006139 Not Cancer Driver No 22 0.104 137 16 0.117 0
TAF12_ENST00000373824 TAF12 Q16514 Transcription initiation factor TFIID subunit 12 chr1 GO:0006139 Not Cancer Driver No 11 0.068 107 7 0.065 0
TAF13 TAF13 Q15543 Transcription initiation factor TFIID subunit 13 chr1 GO:0006139 Not Cancer Driver No 11 0.089 34 3 0.088 2
TAF1C TAF1C Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C chr16 GO:0006139 Not Cancer Driver No 114 0.131 312 35 0.112 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0006139 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 GO:0006139 Not Cancer Driver No 129 0.108 241 34 0.141 1
TAF3 TAF3 Q5VWG9 Transcription initiation factor TFIID subunit 3 chr10 GO:0006139 Not Cancer Driver No 113 0.122 750 90 0.12 0
TAF4 TAF4 O00268 Transcription initiation factor TFIID subunit 4 chr20 GO:0006139 Not Cancer Driver No 112 0.103 975 96 0.098 0
TAF4B_ENST00000269142 TAF4B Q92750 Transcription initiation factor TFIID subunit 4B chr18 GO:0006139 Not Cancer Driver No 86 0.1 482 46 0.095 0
TAF5 TAF5 Q15542 Transcription initiation factor TFIID subunit 5 chr10 GO:0006139 Not Cancer Driver No 61 0.076 294 12 0.041 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 GO:0006139 Not Cancer Driver No 79 0.117 288 32 0.111 2
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 GO:0006139 Not Cancer Driver No 40 0.115 258 31 0.12 0
TAF8 TAF8 Q7Z7C8 Transcription initiation factor TFIID subunit 8 chr6 GO:0006139 Not Cancer Driver No 35 0.113 255 30 0.118 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0006139 Not Cancer Driver No 25 0.095 203 19 0.094 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0006139 Not Cancer Driver No 45 0.123 203 22 0.108 0
TARS2 TARS2 Q9BW92 Threonine--tRNA ligase, mitochondrial chr1 GO:0006139 Not Cancer Driver No 112 0.156 53 10 0.189 1
TARSL2 TARS3 A2RTX5 Threonine--tRNA ligase 2, cytoplasmic chr15 GO:0006139 Not Cancer Driver No 90 0.112 77 14 0.182 0
TARS_ENST00000265112 TARS1 P26639 Threonine--tRNA ligase 1, cytoplasmic chr5 GO:0006139 Not Cancer Driver No 112 0.155 112 22 0.196 2
TBL3 TBL3 Q12788 Transducin beta-like protein 3 chr16 GO:0006139 Not Cancer Driver No 82 0.101 48 8 0.167 0
TBP TBP P20226 TATA-box-binding protein chr6 GO:0006139 Not Cancer Driver No 40 0.118 164 14 0.085 0
TBPL1 TBPL1 P62380 TATA box-binding protein-like 1 chr6 GO:0006139 Not Cancer Driver No 27 0.145 6 0 0.0 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 GO:0006139 Not Cancer Driver No 74 0.117 60 2 0.033 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0006139 Census Yes 52 0.08 649 52 0.08 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0006139 Census, Compendium Yes 122 0.197 516 93 0.18 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0006139 Not Cancer Driver No 75 0.183 185 31 0.168 0
TDO2 TDO2 P48775 Tryptophan 2,3-dioxygenase chr4 GO:0006139 Not Cancer Driver No 64 0.158 31 9 0.29 1
TDP1_ENST00000393454 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0006139 Not Cancer Driver No 81 0.133 179 25 0.14 1
TDRD1 TDRD1 Q9BXT4 Tudor domain-containing protein 1 chr10 GO:0006139 Not Cancer Driver No 200 0.169 216 27 0.125 0
TDRD10 TDRD10 Q5VZ19 Tudor domain-containing protein 10 chr1 GO:0006139 Not Cancer Driver No 85 0.232 31 6 0.194 0
TDRD12_ENST00000444215 TDRD12 Q587J7 Putative ATP-dependent RNA helicase TDRD12 chr19 GO:0006139 Not Cancer Driver No 36 0.031 220 10 0.045 0
TDRD15_ENST00000622654 TDRD15 B5MCY1 Tudor domain-containing protein 15 chr2 GO:0006139 Not Cancer Driver No 8 0.004 99 1 0.01 0
TDRD5_ENST00000294848 TDRD5 Q8NAT2 Tudor domain-containing protein 5 chr1 GO:0006139 Not Cancer Driver No 231 0.235 343 74 0.216 0
TDRD6 TDRD6 O60522 Tudor domain-containing protein 6 chr6 GO:0006139 Not Cancer Driver No 290 0.138 455 50 0.11 0
TDRD7 TDRD7 Q8NHU6 Tudor domain-containing protein 7 chr9 GO:0006139 Not Cancer Driver No 126 0.115 266 38 0.143 0
TDRD9 TDRD9 Q8NDG6 ATP-dependent RNA helicase TDRD9 chr14 GO:0006139 Not Cancer Driver No 156 0.113 108 0 0.0 0
TDRKH_ENST00000368827 TDRKH Q9Y2W6 Tudor and KH domain-containing protein chr1 GO:0006139 Not Cancer Driver No 76 0.135 185 27 0.146 0
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 GO:0006139 Not Cancer Driver No 41 0.133 0 0 0.0 1
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 GO:0006139 Not Cancer Driver No 37 0.103 26 5 0.192 0
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0006139 Not Cancer Driver No 65 0.134 75 15 0.2 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0006139 Not Cancer Driver No 106 0.137 442 43 0.097 0
TEP1 TEP1 Q99973 Telomerase protein component 1 chr14 GO:0006139 Not Cancer Driver No 332 0.126 396 67 0.169 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0006139 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0006139 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0006139 Not Cancer Driver No 28 0.07 310 16 0.052 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0006139 Census Yes 110 0.097 212 16 0.075 31
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0006139 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 GO:0006139 Census, Compendium Yes 191 0.095 1663 176 0.106 1
TET3 TET3 O43151 Methylcytosine dioxygenase TET3 chr2 GO:0006139 Not Cancer Driver No 208 0.116 1272 152 0.119 6
TEX11_ENST00000344304 TEX11 Q8IYF3 Testis-expressed protein 11 chrX GO:0006139 Not Cancer Driver No 139 0.148 30 3 0.1 2
TEX12 TEX12 Q9BXU0 Testis-expressed protein 12 chr11 GO:0006139 Not Cancer Driver No 10 0.081 35 3 0.086 0
TEX15_ENST00000256246 TEX15 Q9BXT5 Testis-expressed protein 15 chr8 GO:0006139 Not Cancer Driver No 479 0.172 1258 223 0.177 0
TEX264_ENST00000416589 TEX264 Q9Y6I9 Testis-expressed protein 264 chr3 GO:0006139 Not Cancer Driver No 40 0.128 107 11 0.103 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 GO:0006139 Not Cancer Driver No 25 0.102 110 15 0.136 1
TFB1M TFB1M Q8WVM0 Dimethyladenosine transferase 1, mitochondrial chr6 GO:0006139 Not Cancer Driver No 50 0.145 26 3 0.115 0
TFB2M TFB2M Q9H5Q4 Dimethyladenosine transferase 2, mitochondrial chr1 GO:0006139 Not Cancer Driver No 60 0.152 36 6 0.167 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 GO:0006139 Not Cancer Driver No 68 0.135 169 23 0.136 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0006139 Not Cancer Driver No 87 0.104 331 39 0.118 0
TGS1 TGS1 Q96RS0 Trimethylguanosine synthase chr8 GO:0006139 Not Cancer Driver No 100 0.117 483 56 0.116 0
THAP9 THAP9 Q9H5L6 DNA transposase THAP9 chr4 GO:0006139 Not Cancer Driver No 82 0.091 46 6 0.13 0
THEM5 THEM5 Q8N1Q8 Acyl-coenzyme A thioesterase THEM5 chr1 GO:0006139 Not Cancer Driver No 39 0.158 1 0 0.0 0
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0006139 Not Cancer Driver No 32 0.107 22 2 0.091 1
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0006139 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0006139 Not Cancer Driver No 154 0.127 367 51 0.139 0
TIPIN TIPIN Q9BVW5 TIMELESS-interacting protein chr15 GO:0006139 Not Cancer Driver No 26 0.086 242 19 0.079 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 GO:0006139 Not Cancer Driver No 149 0.125 919 113 0.123 1
TK1 TK1 P04183 Thymidine kinase, cytosolic chr17 GO:0006139 Not Cancer Driver No 26 0.111 13 4 0.308 0
TK2 TK2 O00142 Thymidine kinase 2, mitochondrial chr16 GO:0006139 Not Cancer Driver No 23 0.087 44 3 0.068 11
TNP1 TNP1 P09430 Spermatid nuclear transition protein 1 chr2 GO:0006139 Not Cancer Driver No 21 0.382 55 21 0.382 0
TOE1 TOE1 Q96GM8 Target of EGR1 protein 1 chr1 GO:0006139 Not Cancer Driver No 44 0.086 210 22 0.105 10
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 GO:0006139 Census, Compendium Yes 93 0.122 391 53 0.136 0
TOP1MT TOP1MT Q969P6 DNA topoisomerase I, mitochondrial chr8 GO:0006139 Not Cancer Driver No 102 0.17 171 32 0.187 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0006139 Compendium Yes 150 0.098 508 59 0.116 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 GO:0006139 Not Cancer Driver No 154 0.095 543 46 0.085 0
TOP3A TOP3A Q13472 DNA topoisomerase 3-alpha chr17 GO:0006139 Not Cancer Driver No 103 0.103 293 31 0.106 2
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 GO:0006139 Not Cancer Driver No 102 0.118 151 17 0.113 0
TOPAZ1 TOPAZ1 Q8N9V7 Protein TOPAZ1 chr3 GO:0006139 Not Cancer Driver No 110 0.065 814 61 0.075 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0006139 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPMT TPMT P51580 Thiopurine S-methyltransferase chr6 GO:0006139 Not Cancer Driver No 23 0.094 13 1 0.077 0
TPRKB_ENST00000272424 TPRKB Q9Y3C4 EKC/KEOPS complex subunit TPRKB chr2 GO:0006139 Not Cancer Driver No 20 0.114 0 0 0.0 2
TPST1 TPST1 O60507 Protein-tyrosine sulfotransferase 1 chr7 GO:0006139 Not Cancer Driver No 50 0.135 49 5 0.102 0
TPST2 TPST2 O60704 Protein-tyrosine sulfotransferase 2 chr22 GO:0006139 Not Cancer Driver No 47 0.125 48 6 0.125 0
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0006139 Not Cancer Driver No 63 0.134 240 33 0.138 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0006139 Not Cancer Driver No 26 0.083 98 10 0.102 18
TREX2_ENST00000370231 TREX2 Q9BQ50 Three prime repair exonuclease 2 chrX GO:0006139 Not Cancer Driver No 33 0.14 23 6 0.261 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0006139 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0006139 Not Cancer Driver No 124 0.143 163 21 0.129 2
TRIR TRIR Q9BQ61 Telomerase RNA component interacting RNase chr19 GO:0006139 Not Cancer Driver No 17 0.097 176 17 0.097 0
TRIT1 TRIT1 Q9H3H1 tRNA dimethylallyltransferase chr1 GO:0006139 Not Cancer Driver No 61 0.131 121 19 0.157 1
TRMT10A_ENST00000394876 TRMT10A Q8TBZ6 tRNA methyltransferase 10 homolog A chr4 GO:0006139 Not Cancer Driver No 49 0.145 182 28 0.154 1
TRMT10B TRMT10B Q6PF06 tRNA methyltransferase 10 homolog B chr9 GO:0006139 Not Cancer Driver No 35 0.111 75 13 0.173 0
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:0006139 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRMT112 TRMT112 Q9UI30 Multifunctional methyltransferase subunit TRM112-like protein chr11 GO:0006139 Not Cancer Driver No 15 0.12 17 2 0.118 0
TRMT1L TRMT1L Q7Z2T5 TRMT1-like protein chr1 GO:0006139 Not Cancer Driver No 71 0.097 241 19 0.079 0
TRMT1_ENST00000357720 TRMT1 Q9NXH9 tRNA (guanine(26)-N(2))-dimethyltransferase chr19 GO:0006139 Not Cancer Driver No 82 0.124 200 24 0.12 0
TRMT5 TRMT5 Q32P41 tRNA (guanine(37)-N1)-methyltransferase chr14 GO:0006139 Not Cancer Driver No 46 0.09 67 5 0.075 2
TRMT6 TRMT6 Q9UJA5 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 chr20 GO:0006139 Not Cancer Driver No 42 0.085 208 17 0.082 0
TRMT61A TRMT61A Q96FX7 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A chr14 GO:0006139 Not Cancer Driver No 16 0.055 74 9 0.122 0
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 GO:0006139 Not Cancer Driver No 48 0.101 123 10 0.081 0
TRMU TRMU O75648 Mitochondrial tRNA-specific 2-thiouridylase 1 chr22 GO:0006139 Not Cancer Driver No 40 0.095 28 5 0.179 2
TRNT1 TRNT1 Q96Q11 CCA tRNA nucleotidyltransferase 1, mitochondrial chr3 GO:0006139 Not Cancer Driver No 60 0.138 49 8 0.163 7
TRUB1 TRUB1 Q8WWH5 Pseudouridylate synthase TRUB1 chr10 GO:0006139 Not Cancer Driver No 42 0.12 120 15 0.125 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 GO:0006139 Not Cancer Driver No 37 0.112 73 7 0.096 0
TSEN2 TSEN2 Q8NCE0 tRNA-splicing endonuclease subunit Sen2 chr3 GO:0006139 Not Cancer Driver No 54 0.116 153 17 0.111 1
TSEN34_ENST00000396383 TSEN34 Q9BSV6 tRNA-splicing endonuclease subunit Sen34 chr19 GO:0006139 Not Cancer Driver No 40 0.129 176 22 0.125 1
TSEN54 TSEN54 Q7Z6J9 tRNA-splicing endonuclease subunit Sen54 chr17 GO:0006139 Not Cancer Driver No 44 0.084 279 29 0.104 4
TSN TSN Q15631 Translin chr2 GO:0006139 Not Cancer Driver No 30 0.132 0 0 0.0 0
TSNAX TSNAX Q99598 Translin-associated protein X chr1 GO:0006139 Not Cancer Driver No 23 0.079 68 3 0.044 0
TSR3 TSR3 Q9UJK0 18S rRNA aminocarboxypropyltransferase chr16 GO:0006139 Not Cancer Driver No 31 0.099 144 13 0.09 0
TSTA3_ENST00000529064 GFUS Q13630 GDP-L-fucose synthase chr8 GO:0006139 Not Cancer Driver No 38 0.118 19 2 0.105 0
TTC37 TTC37 Q6PGP7 Tetratricopeptide repeat protein 37 chr5 GO:0006139 Not Cancer Driver No 164 0.105 59 3 0.051 3
TTF1 TTF1 Q15361 Transcription termination factor 1 chr9 GO:0006139 Not Cancer Driver No 105 0.116 535 59 0.11 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 GO:0006139 Not Cancer Driver No 118 0.102 550 50 0.091 0
TTR TTR P02766 Transthyretin chr18 GO:0006139 Not Cancer Driver No 28 0.19 25 8 0.32 75
TUT1_ENST00000476907 TUT1 Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase chr11 GO:0006139 Not Cancer Driver No 97 0.111 410 50 0.122 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0006139 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0006139 Not Cancer Driver No 159 0.106 659 74 0.112 0
TYMP_ENST00000395680 TYMP P19971 Thymidine phosphorylase chr22 GO:0006139 Not Cancer Driver No 28 0.058 143 7 0.049 5
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0006139 Not Cancer Driver No 22 0.07 41 0 0.0 0
TYW1 TYW1 Q9NV66 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 chr7 GO:0006139 Not Cancer Driver No 102 0.139 152 21 0.138 0
TYW1B TYW1B Q6NUM6 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B chr7 GO:0006139 Not Cancer Driver No 108 0.162 161 28 0.174 0
TYW5 TYW5 A2RUC4 tRNA wybutosine-synthesizing protein 5 chr2 GO:0006139 Not Cancer Driver No 32 0.102 11 1 0.091 0
UAP1 UAP1 Q16222 UDP-N-acetylhexosamine pyrophosphorylase chr1 GO:0006139 Not Cancer Driver No 67 0.128 78 7 0.09 0
UAP1L1 UAP1L1 Q3KQV9 UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 chr9 GO:0006139 Not Cancer Driver No 36 0.071 120 5 0.042 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0006139 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0006139 Not Cancer Driver No 100 0.131 567 77 0.136 1
UCK1_ENST00000372215 UCK1 Q9HA47 Uridine-cytidine kinase 1 chr9 GO:0006139 Not Cancer Driver No 35 0.126 70 3 0.043 0
UCK2 UCK2 Q9BZX2 Uridine-cytidine kinase 2 chr1 GO:0006139 Not Cancer Driver No 43 0.165 61 10 0.164 0
UCKL1 UCKL1 Q9NWZ5 Uridine-cytidine kinase-like 1 chr20 GO:0006139 Not Cancer Driver No 54 0.099 134 15 0.112 0
UGDH_ENST00000506179 UGDH O60701 UDP-glucose 6-dehydrogenase chr4 GO:0006139 Not Cancer Driver No 54 0.109 39 4 0.103 5
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 GO:0006139 Not Cancer Driver No 169 0.109 161 20 0.124 0
UGGT2 UGGT2 Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 chr13 GO:0006139 Not Cancer Driver No 190 0.125 64 6 0.094 0
UGP2 UGP2 Q16851 UTP--glucose-1-phosphate uridylyltransferase chr2 GO:0006139 Not Cancer Driver No 65 0.128 55 7 0.127 1
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0006139 Not Cancer Driver No 97 0.122 353 49 0.139 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 GO:0006139 Not Cancer Driver No 88 0.11 253 22 0.087 0
UMPS UMPS P11172 Uridine 5'-monophosphate synthase chr3 GO:0006139 Not Cancer Driver No 58 0.121 18 2 0.111 3
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0006139 Not Cancer Driver No 34 0.109 96 13 0.135 1
UPB1 UPB1 Q9UBR1 Beta-ureidopropionase chr22 GO:0006139 Not Cancer Driver No 66 0.172 22 7 0.318 8
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0006139 Not Cancer Driver No 146 0.129 329 36 0.109 0
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 GO:0006139 Not Cancer Driver No 47 0.152 13 3 0.231 0
UPP2_ENST00000005756 UPP2 O95045 Uridine phosphorylase 2 chr2 GO:0006139 Not Cancer Driver No 55 0.174 5 1 0.2 0
UPRT UPRT Q96BW1 Uracil phosphoribosyltransferase homolog chrX GO:0006139 Not Cancer Driver No 64 0.207 76 15 0.197 0
URAD URAD A6NGE7 Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase chr13 GO:0006139 Not Cancer Driver No 14 0.081 21 0 0.0 0
URM1_ENST00000372853 URM1 Q9BTM9 Ubiquitin-related modifier 1 chr9 GO:0006139 Not Cancer Driver No 7 0.069 0 0 0.0 0
USB1 USB1 Q9BQ65 U6 snRNA phosphodiesterase 1 chr16 GO:0006139 Not Cancer Driver No 28 0.106 76 5 0.066 0
USP45 USP45 Q70EL2 Ubiquitin carboxyl-terminal hydrolase 45 chr6 GO:0006139 Not Cancer Driver No 96 0.118 275 28 0.102 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0006139 Not Cancer Driver No 170 0.154 215 45 0.209 0
USPL1 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 GO:0006139 Not Cancer Driver No 107 0.098 578 55 0.095 0
UTP20 UTP20 O75691 Small subunit processome component 20 homolog chr12 GO:0006139 Not Cancer Driver No 324 0.116 314 35 0.111 0
UTP23 UTP23 Q9BRU9 rRNA-processing protein UTP23 homolog chr8 GO:0006139 Not Cancer Driver No 35 0.141 97 16 0.165 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0006139 Not Cancer Driver No 89 0.127 243 28 0.115 0
UVSSA UVSSA Q2YD98 UV-stimulated scaffold protein A chr4 GO:0006139 Not Cancer Driver No 101 0.142 519 70 0.135 1
UXS1_ENST00000409501 UXS1 Q8NBZ7 UDP-glucuronic acid decarboxylase 1 chr2 GO:0006139 Not Cancer Driver No 70 0.167 69 9 0.13 0
VARS VARS1 P26640 Valine--tRNA ligase chr6 GO:0006139 Not Cancer Driver No 145 0.115 251 26 0.104 0
VARS2_ENST00000321897 VARS2 Q5ST30 Valine--tRNA ligase, mitochondrial chr6 GO:0006139 Not Cancer Driver No 111 0.104 253 21 0.083 3
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0006139 Not Cancer Driver No 88 0.109 186 16 0.086 16
VCPIP1 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 GO:0006139 Not Cancer Driver No 133 0.109 543 61 0.112 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0006139 Not Cancer Driver No 64 0.15 102 16 0.157 14
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 GO:0006139 Not Cancer Driver No 211 0.116 631 93 0.147 0
VRTN VRTN Q9H8Y1 Vertnin chr14 GO:0006139 Not Cancer Driver No 153 0.218 132 27 0.205 0
WARS WARS1 P23381 Tryptophan--tRNA ligase, cytoplasmic chr14 GO:0006139 Not Cancer Driver No 62 0.132 90 13 0.144 1
WARS2 WARS2 Q9UGM6 Tryptophan--tRNA ligase, mitochondrial chr1 GO:0006139 Not Cancer Driver No 67 0.186 31 4 0.129 5
WDR4 WDR4 P57081 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 chr21 GO:0006139 Not Cancer Driver No 37 0.09 49 4 0.082 2
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0006139 Census, Compendium Yes 164 0.115 373 41 0.11 2
WTAP_ENST00000621533 WTAP Q15007 Pre-mRNA-splicing regulator WTAP chr6 GO:0006139 Not Cancer Driver No 60 0.152 305 50 0.164 0
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 GO:0006139 Not Cancer Driver No 128 0.15 127 17 0.134 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0006139 Not Cancer Driver No 279 0.209 134 24 0.179 1
XPA XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:0006139 Census Yes 27 0.099 121 13 0.107 5
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:0006139 Census, Compendium Yes 88 0.094 479 48 0.1 2
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 GO:0006139 Not Cancer Driver No 112 0.093 64 7 0.109 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0006139 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0006139 Not Cancer Driver No 36 0.129 9 1 0.111 2
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0006139 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 GO:0006139 Not Cancer Driver No 47 0.14 171 31 0.181 3
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0006139 Not Cancer Driver No 66 0.108 140 12 0.086 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0006139 Not Cancer Driver No 213 0.125 577 65 0.113 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0006139 Not Cancer Driver No 129 0.136 427 63 0.148 0
YARS YARS1 P54577 Tyrosine--tRNA ligase, cytoplasmic chr1 GO:0006139 Not Cancer Driver No 62 0.117 109 9 0.083 3
YARS2 YARS2 Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial chr12 GO:0006139 Not Cancer Driver No 59 0.124 62 11 0.177 2
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0006139 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBED9 ZBED9 Q6R2W3 SCAN domain-containing protein 3 chr6 GO:0006139 Not Cancer Driver No 333 0.251 317 84 0.265 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0006139 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0006139 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0006139 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H13 ZC3H13 Q5T200 Zinc finger CCCH domain-containing protein 13 chr13 GO:0006139 Not Cancer Driver No 250 0.15 1443 224 0.155 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0006139 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZCCHC8 ZCCHC8 Q6NZY4 Zinc finger CCHC domain-containing protein 8 chr12 GO:0006139 Census Yes 81 0.115 503 56 0.111 1
ZDBF2 ZDBF2 Q9HCK1 DBF4-type zinc finger-containing protein 2 chr2 GO:0006139 Not Cancer Driver No 510 0.217 1664 380 0.228 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0006139 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0006139 Compendium Yes 57 0.169 212 30 0.142 0
ZFP57_ENST00000376881 ZFP57 Q9NU63 Zinc finger protein 57 homolog chr6 GO:0006139 Not Cancer Driver No 82 0.181 153 33 0.216 3
ZGRF1 ZGRF1 Q86YA3 Protein ZGRF1 chr4 GO:0006139 Not Cancer Driver No 216 0.103 881 95 0.108 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0006139 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF445_ENST00000425708 ZNF445 P59923 Zinc finger protein 445 chr3 GO:0006139 Not Cancer Driver No 136 0.132 398 61 0.153 0
ZNF473_ENST00000270617 ZNF473 Q8WTR7 Zinc finger protein 473 chr19 GO:0006139 Not Cancer Driver No 104 0.119 282 27 0.096 0
ZNF830 ZNF830 Q96NB3 Zinc finger protein 830 chr17 GO:0006139 Not Cancer Driver No 39 0.105 312 37 0.119 0
ZNRD1 POLR1H Q9P1U0 DNA-directed RNA polymerase I subunit RPA12 chr6 GO:0006139 Not Cancer Driver No 6 0.048 14 1 0.071 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0006139 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZRANB3 ZRANB3 Q5FWF4 DNA annealing helicase and endonuclease ZRANB3 chr2 GO:0006139 Not Cancer Driver No 126 0.117 261 31 0.119 0