Total number of protein in "GO:0006099" GO term: 31
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACO1_ENST00000541043 | ACO1 | P21399 | Cytoplasmic aconitate hydratase | chr9 | GO:0006099 | Not Cancer Driver | No | 108 | 0.121 | 44 | 14 | 0.318 | 0 |
ACO2 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | GO:0006099 | Not Cancer Driver | No | 94 | 0.121 | 172 | 19 | 0.11 | 5 |
CS | CS | O75390 | Citrate synthase, mitochondrial | chr12 | GO:0006099 | Not Cancer Driver | No | 50 | 0.107 | 13 | 2 | 0.154 | 0 |
DHTKD1 | DHTKD1 | Q96HY7 | 2-oxoadipate dehydrogenase complex component E1 | chr10 | GO:0006099 | Not Cancer Driver | No | 119 | 0.129 | 117 | 15 | 0.128 | 2 |
DLAT | DLAT | P10515 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | chr11 | GO:0006099 | Not Cancer Driver | No | 63 | 0.097 | 294 | 42 | 0.143 | 0 |
DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | GO:0006099 | Not Cancer Driver | No | 53 | 0.117 | 190 | 32 | 0.168 | 1 |
FH | FH | P07954 | Fumarate hydratase, mitochondrial | chr1 | GO:0006099 | Census, Compendium | Yes | 67 | 0.131 | 76 | 5 | 0.066 | 13 |
IDH1 | IDH1 | O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | chr2 | GO:0006099 | Census, Compendium | Yes | 553 | 1.336 | 37 | 3 | 0.081 | 0 |
IDH2 | IDH2 | P48735 | Isocitrate dehydrogenase [NADP], mitochondrial | chr15 | GO:0006099 | Census, Compendium | Yes | 74 | 0.164 | 59 | 1 | 0.017 | 7 |
IDH3A | IDH3A | P50213 | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | chr15 | GO:0006099 | Not Cancer Driver | No | 41 | 0.112 | 47 | 11 | 0.234 | 0 |
IDH3B_ENST00000380843 | IDH3B | O43837 | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial | chr20 | GO:0006099 | Not Cancer Driver | No | 32 | 0.083 | 49 | 3 | 0.061 | 1 |
IDH3G | IDH3G | P51553 | Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial | chrX | GO:0006099 | Not Cancer Driver | No | 48 | 0.122 | 77 | 9 | 0.117 | 0 |
IREB2 | IREB2 | P48200 | Iron-responsive element-binding protein 2 | chr15 | GO:0006099 | Not Cancer Driver | No | 126 | 0.131 | 107 | 13 | 0.121 | 0 |
MDH1B | MDH1B | Q5I0G3 | Putative malate dehydrogenase 1B | chr2 | GO:0006099 | Not Cancer Driver | No | 103 | 0.199 | 46 | 13 | 0.283 | 0 |
MDH1_ENST00000233114 | MDH1 | P40925 | Malate dehydrogenase, cytoplasmic | chr2 | GO:0006099 | Not Cancer Driver | No | 41 | 0.123 | 18 | 2 | 0.111 | 1 |
MDH2 | MDH2 | P40926 | Malate dehydrogenase, mitochondrial | chr7 | GO:0006099 | Not Cancer Driver | No | 39 | 0.115 | 8 | 1 | 0.125 | 3 |
MRPS36 | MRPS36 | P82909 | Alpha-ketoglutarate dehydrogenase component 4 | chr5 | GO:0006099 | Not Cancer Driver | No | 12 | 0.117 | 103 | 12 | 0.117 | 0 |
NNT_ENST00000344920 | NNT | Q13423 | NAD(P) transhydrogenase, mitochondrial | chr5 | GO:0006099 | Not Cancer Driver | No | 129 | 0.119 | 47 | 6 | 0.128 | 11 |
OGDH | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | GO:0006099 | Not Cancer Driver | No | 150 | 0.147 | 106 | 19 | 0.179 | 0 |
OGDHL | OGDHL | Q9ULD0 | 2-oxoglutarate dehydrogenase-like, mitochondrial | chr10 | GO:0006099 | Not Cancer Driver | No | 262 | 0.259 | 128 | 38 | 0.297 | 0 |
PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | GO:0006099 | Not Cancer Driver | No | 70 | 0.179 | 43 | 6 | 0.14 | 20 |
PDHA2 | PDHA2 | P29803 | Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial | chr4 | GO:0006099 | Not Cancer Driver | No | 163 | 0.42 | 41 | 17 | 0.415 | 0 |
PDHB | PDHB | P11177 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | chr3 | GO:0006099 | Not Cancer Driver | No | 32 | 0.089 | 4 | 0 | 0.0 | 2 |
SDHA | SDHA | P31040 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | chr5 | GO:0006099 | Census | Yes | 115 | 0.173 | 71 | 13 | 0.183 | 7 |
SDHAF2 | SDHAF2 | Q9NX18 | Succinate dehydrogenase assembly factor 2, mitochondrial | chr11 | GO:0006099 | Census | Yes | 29 | 0.175 | 22 | 5 | 0.227 | 1 |
SDHB | SDHB | P21912 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | chr1 | GO:0006099 | Census | Yes | 37 | 0.132 | 17 | 3 | 0.176 | 23 |
SDHC | SDHC | Q99643 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | chr1 | GO:0006099 | Census | Yes | 16 | 0.095 | 0 | 0 | 0.0 | 0 |
SDHD | SDHD | O14521 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | chr11 | GO:0006099 | Census | Yes | 22 | 0.138 | 0 | 0 | 0.0 | 10 |
SUCLA2 | SUCLA2 | Q9P2R7 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | chr13 | GO:0006099 | Not Cancer Driver | No | 51 | 0.11 | 46 | 6 | 0.13 | 3 |
SUCLG1 | SUCLG1 | P53597 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | chr2 | GO:0006099 | Not Cancer Driver | No | 48 | 0.139 | 57 | 8 | 0.14 | 3 |
SUCLG2_ENST00000307227 | SUCLG2 | Q96I99 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | chr3 | GO:0006099 | Not Cancer Driver | No | 48 | 0.111 | 12 | 2 | 0.167 | 0 |