Total number of protein in "GO:0006091" GO term: 103
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AACS | AACS | Q86V21 | Acetoacetyl-CoA synthetase | chr12 | GO:0006091 | Not Cancer Driver | No | 92 | 0.137 | 16 | 0 | 0.0 | 0 |
| ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | GO:0006091 | Not Cancer Driver | No | 45 | 0.105 | 32 | 1 | 0.031 | 10 |
| ACO2 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | GO:0006091 | Not Cancer Driver | No | 94 | 0.121 | 172 | 19 | 0.11 | 5 |
| ACOX1_ENST00000301608 | ACOX1 | Q15067 | Peroxisomal acyl-coenzyme A oxidase 1 | chr17 | GO:0006091 | Not Cancer Driver | No | 71 | 0.108 | 63 | 11 | 0.175 | 7 |
| ACSS1 | ACSS1 | Q9NUB1 | Acetyl-coenzyme A synthetase 2-like, mitochondrial | chr20 | GO:0006091 | Not Cancer Driver | No | 79 | 0.115 | 76 | 6 | 0.079 | 0 |
| ACSS2_ENST00000360596 | ACSS2 | Q9NR19 | Acetyl-coenzyme A synthetase, cytoplasmic | chr20 | GO:0006091 | Not Cancer Driver | No | 62 | 0.088 | 111 | 6 | 0.054 | 0 |
| ACSS3 | ACSS3 | Q9H6R3 | Acyl-CoA synthetase short-chain family member 3, mitochondrial | chr12 | GO:0006091 | Not Cancer Driver | No | 194 | 0.283 | 63 | 10 | 0.159 | 0 |
| ADH1A | ADH1A | P07327 | Alcohol dehydrogenase 1A | chr4 | GO:0006091 | Not Cancer Driver | No | 73 | 0.195 | 6 | 3 | 0.5 | 0 |
| ADH1B | ADH1B | P00325 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B | chr4 | GO:0006091 | Not Cancer Driver | No | 108 | 0.288 | 6 | 4 | 0.667 | 0 |
| ADH1C | ADH1C | P00326 | Alcohol dehydrogenase 1C | chr4 | GO:0006091 | Not Cancer Driver | No | 116 | 0.309 | 6 | 5 | 0.833 | 0 |
| ADH4_ENST00000265512 | ADH4 | P08319 | All-trans-retinol dehydrogenase [NAD(+)] ADH4 | chr4 | GO:0006091 | Not Cancer Driver | No | 49 | 0.129 | 5 | 1 | 0.2 | 0 |
| ADH5 | ADH5 | P11766 | Alcohol dehydrogenase class-3 | chr4 | GO:0006091 | Not Cancer Driver | No | 36 | 0.096 | 2 | 1 | 0.5 | 0 |
| ADH6_ENST00000237653 | ADH6 | P28332 | Alcohol dehydrogenase 6 | chr4 | GO:0006091 | Not Cancer Driver | No | 71 | 0.193 | 0 | 0 | 0.0 | 0 |
| ADH7_ENST00000209665 | ADH7 | P40394 | All-trans-retinol dehydrogenase [NAD(+)] ADH7 | chr4 | GO:0006091 | Not Cancer Driver | No | 74 | 0.192 | 15 | 2 | 0.133 | 0 |
| ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0006091 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
| ADPGK | ADPGK | Q9BRR6 | ADP-dependent glucokinase | chr15 | GO:0006091 | Not Cancer Driver | No | 38 | 0.076 | 24 | 0 | 0.0 | 0 |
| ADRB3 | ADRB3 | P13945 | Beta-3 adrenergic receptor | chr8 | GO:0006091 | Not Cancer Driver | No | 40 | 0.098 | 44 | 6 | 0.136 | 0 |
| AGL_ENST00000361915 | AGL | P35573 | Glycogen debranching enzyme | chr1 | GO:0006091 | Not Cancer Driver | No | 182 | 0.119 | 143 | 23 | 0.161 | 1 |
| ALDH1L1_ENST00000393434 | ALDH1L1 | O75891 | Cytosolic 10-formyltetrahydrofolate dehydrogenase | chr3 | GO:0006091 | Not Cancer Driver | No | 159 | 0.176 | 87 | 19 | 0.218 | 0 |
| ALDH1L2 | ALDH1L2 | Q3SY69 | Mitochondrial 10-formyltetrahydrofolate dehydrogenase | chr12 | GO:0006091 | Not Cancer Driver | No | 108 | 0.117 | 81 | 12 | 0.148 | 0 |
| ASIP_ENST00000374954 | ASIP | P42127 | Agouti-signaling protein | chr20 | GO:0006091 | Not Cancer Driver | No | 16 | 0.121 | 36 | 9 | 0.25 | 0 |
| ATP5F1B | ATP5F1B | P06576 | ATP synthase subunit beta, mitochondrial | chr12 | GO:0006091 | Not Cancer Driver | No | 60 | 0.113 | 85 | 8 | 0.094 | 0 |
| ATP5IF1 | ATP5IF1 | Q9UII2 | ATPase inhibitor, mitochondrial | chr1 | GO:0006091 | Not Cancer Driver | No | 8 | 0.075 | 85 | 7 | 0.082 | 0 |
| AVP | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0006091 | Not Cancer Driver | No | 14 | 0.085 | 26 | 0 | 0.0 | 39 |
| AVPR1A | AVPR1A | P37288 | Vasopressin V1a receptor | chr12 | GO:0006091 | Not Cancer Driver | No | 105 | 0.251 | 68 | 25 | 0.368 | 0 |
| CEBPA | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0006091 | Census, Compendium | Yes | 12 | 0.034 | 342 | 12 | 0.035 | 1 |
| COA6_ENST00000366613 | COA6 | Q5JTJ3 | Cytochrome c oxidase assembly factor 6 homolog | chr1 | GO:0006091 | Not Cancer Driver | No | 19 | 0.152 | 13 | 2 | 0.154 | 2 |
| COX17_ENST00000497116 | COX17 | Q14061 | Cytochrome c oxidase copper chaperone | chr3 | GO:0006091 | Not Cancer Driver | No | 7 | 0.111 | 15 | 2 | 0.133 | 0 |
| COX4I1 | COX4I1 | P13073 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | chr16 | GO:0006091 | Not Cancer Driver | No | 17 | 0.101 | 5 | 1 | 0.2 | 1 |
| COX4I2 | COX4I2 | Q96KJ9 | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial | chr20 | GO:0006091 | Not Cancer Driver | No | 26 | 0.152 | 36 | 4 | 0.111 | 1 |
| COX6A1 | COX6A1 | P12074 | Cytochrome c oxidase subunit 6A1, mitochondrial | chr12 | GO:0006091 | Not Cancer Driver | No | 17 | 0.156 | 48 | 5 | 0.104 | 0 |
| COX6A2 | COX6A2 | Q02221 | Cytochrome c oxidase subunit 6A2, mitochondrial | chr16 | GO:0006091 | Not Cancer Driver | No | 14 | 0.144 | 42 | 8 | 0.19 | 2 |
| COX6C_ENST00000522940 | COX6C | P09669 | Cytochrome c oxidase subunit 6C | chr8 | GO:0006091 | Census | Yes | 14 | 0.187 | 0 | 0 | 0.0 | 0 |
| COX7A1 | COX7A1 | P24310 | Cytochrome c oxidase subunit 7A1, mitochondrial | chr19 | GO:0006091 | Not Cancer Driver | No | 10 | 0.127 | 0 | 0 | 0.0 | 0 |
| COX7C | COX7C | P15954 | Cytochrome c oxidase subunit 7C, mitochondrial | chr5 | GO:0006091 | Not Cancer Driver | No | 7 | 0.111 | 0 | 0 | 0.0 | 0 |
| COX8A | COX8A | P10176 | Cytochrome c oxidase subunit 8A, mitochondrial | chr11 | GO:0006091 | Not Cancer Driver | No | 10 | 0.145 | 1 | 0 | 0.0 | 0 |
| CROT_ENST00000331536 | CROT | Q9UKG9 | Peroxisomal carnitine O-octanoyltransferase | chr7 | GO:0006091 | Not Cancer Driver | No | 107 | 0.175 | 32 | 2 | 0.062 | 0 |
| CYB5R4 | CYB5R4 | Q7L1T6 | Cytochrome b5 reductase 4 | chr6 | GO:0006091 | Not Cancer Driver | No | 73 | 0.14 | 56 | 10 | 0.179 | 0 |
| DERA | DERA | Q9Y315 | Deoxyribose-phosphate aldolase | chr12 | GO:0006091 | Not Cancer Driver | No | 33 | 0.104 | 2 | 0 | 0.0 | 0 |
| DHTKD1 | DHTKD1 | Q96HY7 | 2-oxoadipate dehydrogenase complex component E1 | chr10 | GO:0006091 | Not Cancer Driver | No | 119 | 0.129 | 117 | 15 | 0.128 | 2 |
| DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | GO:0006091 | Not Cancer Driver | No | 53 | 0.117 | 190 | 32 | 0.168 | 1 |
| ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | GO:0006091 | Not Cancer Driver | No | 51 | 0.118 | 21 | 2 | 0.095 | 0 |
| ENO2 | ENO2 | P09104 | Gamma-enolase | chr12 | GO:0006091 | Not Cancer Driver | No | 48 | 0.111 | 12 | 2 | 0.167 | 0 |
| ENPP1 | ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | chr6 | GO:0006091 | Not Cancer Driver | No | 148 | 0.16 | 101 | 5 | 0.05 | 33 |
| FDXR_ENST00000293195 | FDXR | P22570 | NADPH:adrenodoxin oxidoreductase, mitochondrial | chr17 | GO:0006091 | Not Cancer Driver | No | 68 | 0.138 | 102 | 14 | 0.137 | 4 |
| FECH_ENST00000262093 | FECH | P22830 | Ferrochelatase, mitochondrial | chr18 | GO:0006091 | Not Cancer Driver | No | 52 | 0.123 | 57 | 8 | 0.14 | 23 |
| FOXK1 | FOXK1 | P85037 | Forkhead box protein K1 | chr7 | GO:0006091 | Not Cancer Driver | No | 97 | 0.132 | 511 | 65 | 0.127 | 0 |
| FOXK2 | FOXK2 | Q01167 | Forkhead box protein K2 | chr17 | GO:0006091 | Not Cancer Driver | No | 79 | 0.12 | 548 | 64 | 0.117 | 0 |
| G6PC | G6PC1 | P35575 | Glucose-6-phosphatase catalytic subunit 1 | chr17 | GO:0006091 | Not Cancer Driver | No | 67 | 0.188 | 0 | 0 | 0.0 | 54 |
| G6PD_ENST00000621232 | G6PD | P11413 | Glucose-6-phosphate 1-dehydrogenase | chrX | GO:0006091 | Not Cancer Driver | No | 86 | 0.167 | 28 | 3 | 0.107 | 58 |
| GAA_ENST00000390015 | GAA | P10253 | Lysosomal alpha-glucosidase | chr17 | GO:0006091 | Not Cancer Driver | No | 101 | 0.106 | 147 | 18 | 0.122 | 131 |
| GALK1 | GALK1 | P51570 | Galactokinase | chr17 | GO:0006091 | Not Cancer Driver | No | 31 | 0.079 | 43 | 5 | 0.116 | 11 |
| GBE1 | GBE1 | Q04446 | 1,4-alpha-glucan-branching enzyme | chr3 | GO:0006091 | Not Cancer Driver | No | 101 | 0.144 | 8 | 0 | 0.0 | 9 |
| GCGR | GCGR | P47871 | Glucagon receptor | chr17 | GO:0006091 | Not Cancer Driver | No | 16 | 0.034 | 56 | 2 | 0.036 | 4 |
| GCK_ENST00000403799 | GCK | P35557 | Hexokinase-4 | chr7 | GO:0006091 | Not Cancer Driver | No | 88 | 0.189 | 73 | 14 | 0.192 | 107 |
| GIPR | GIPR | P48546 | Gastric inhibitory polypeptide receptor | chr19 | GO:0006091 | Not Cancer Driver | No | 45 | 0.097 | 41 | 0 | 0.0 | 0 |
| GNPDA1_ENST00000311337 | GNPDA1 | P46926 | Glucosamine-6-phosphate isomerase 1 | chr5 | GO:0006091 | Not Cancer Driver | No | 23 | 0.08 | 17 | 3 | 0.176 | 0 |
| GYS2 | GYS2 | P54840 | Glycogen [starch] synthase, liver | chr12 | GO:0006091 | Not Cancer Driver | No | 153 | 0.218 | 99 | 21 | 0.212 | 6 |
| H6PD_ENST00000377403 | H6PD | O95479 | GDH/6PGL endoplasmic bifunctional protein | chr1 | GO:0006091 | Not Cancer Driver | No | 96 | 0.121 | 39 | 3 | 0.077 | 2 |
| HK1_ENST00000359426 | HK1 | P19367 | Hexokinase-1 | chr10 | GO:0006091 | Not Cancer Driver | No | 127 | 0.138 | 75 | 16 | 0.213 | 6 |
| HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:0006091 | Not Cancer Driver | No | 138 | 0.15 | 77 | 7 | 0.091 | 0 |
| HK3 | HK3 | P52790 | Hexokinase-3 | chr5 | GO:0006091 | Not Cancer Driver | No | 164 | 0.178 | 71 | 17 | 0.239 | 0 |
| HMGCL | HMGCL | P35914 | Hydroxymethylglutaryl-CoA lyase, mitochondrial | chr1 | GO:0006091 | Not Cancer Driver | No | 17 | 0.052 | 8 | 2 | 0.25 | 19 |
| HMGCLL1 | HMGCLL1 | Q8TB92 | 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic | chr6 | GO:0006091 | Not Cancer Driver | No | 113 | 0.305 | 2 | 1 | 0.5 | 0 |
| HMGCS2 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0006091 | Not Cancer Driver | No | 92 | 0.181 | 29 | 4 | 0.138 | 19 |
| MCHR1 | MCHR1 | Q99705 | Melanin-concentrating hormone receptor 1 | chr22 | GO:0006091 | Not Cancer Driver | No | 64 | 0.152 | 100 | 12 | 0.12 | 0 |
| NNT_ENST00000344920 | NNT | Q13423 | NAD(P) transhydrogenase, mitochondrial | chr5 | GO:0006091 | Not Cancer Driver | No | 129 | 0.119 | 47 | 6 | 0.128 | 11 |
| OGDH | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | GO:0006091 | Not Cancer Driver | No | 150 | 0.147 | 106 | 19 | 0.179 | 0 |
| OXCT1 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | GO:0006091 | Not Cancer Driver | No | 80 | 0.154 | 39 | 5 | 0.128 | 11 |
| OXCT2 | OXCT2 | Q9BYC2 | Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial | chr1 | GO:0006091 | Not Cancer Driver | No | 55 | 0.106 | 56 | 6 | 0.107 | 0 |
| PDX1 | PDX1 | P52945 | Pancreas/duodenum homeobox protein 1 | chr13 | GO:0006091 | Not Cancer Driver | No | 32 | 0.113 | 238 | 23 | 0.097 | 0 |
| PFKL | PFKL | P17858 | ATP-dependent 6-phosphofructokinase, liver type | chr21 | GO:0006091 | Not Cancer Driver | No | 91 | 0.117 | 29 | 4 | 0.138 | 0 |
| PFKM_ENST00000550924 | PFKM | P08237 | ATP-dependent 6-phosphofructokinase, muscle type | chr12 | GO:0006091 | Not Cancer Driver | No | 80 | 0.103 | 70 | 8 | 0.114 | 9 |
| PFKP | PFKP | Q01813 | ATP-dependent 6-phosphofructokinase, platelet type | chr10 | GO:0006091 | Not Cancer Driver | No | 133 | 0.17 | 43 | 10 | 0.233 | 0 |
| PGD | PGD | P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | chr1 | GO:0006091 | Not Cancer Driver | No | 73 | 0.151 | 19 | 3 | 0.158 | 0 |
| PGLS | PGLS | O95336 | 6-phosphogluconolactonase | chr19 | GO:0006091 | Not Cancer Driver | No | 20 | 0.078 | 36 | 4 | 0.111 | 0 |
| PHKA1 | PHKA1 | P46020 | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform | chrX | GO:0006091 | Not Cancer Driver | No | 228 | 0.186 | 188 | 43 | 0.229 | 1 |
| PHKA2 | PHKA2 | P46019 | Phosphorylase b kinase regulatory subunit alpha, liver isoform | chrX | GO:0006091 | Not Cancer Driver | No | 199 | 0.161 | 193 | 37 | 0.192 | 17 |
| PHKB | PHKB | Q93100 | Phosphorylase b kinase regulatory subunit beta | chr16 | GO:0006091 | Not Cancer Driver | No | 147 | 0.134 | 98 | 9 | 0.092 | 1 |
| PHKG2 | PHKG2 | P15735 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | chr16 | GO:0006091 | Not Cancer Driver | No | 48 | 0.118 | 50 | 6 | 0.12 | 4 |
| POMC | POMC | P01189 | Pro-opiomelanocortin | chr2 | GO:0006091 | Not Cancer Driver | No | 50 | 0.187 | 198 | 38 | 0.192 | 0 |
| PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | GO:0006091 | Not Cancer Driver | No | 72 | 0.163 | 69 | 7 | 0.101 | 0 |
| PPP1R2 | PPP1R2 | P41236 | Protein phosphatase inhibitor 2 | chr3 | GO:0006091 | Not Cancer Driver | No | 19 | 0.093 | 205 | 19 | 0.093 | 0 |
| PYGB | PYGB | P11216 | Glycogen phosphorylase, brain form | chr20 | GO:0006091 | Not Cancer Driver | No | 118 | 0.14 | 29 | 5 | 0.172 | 0 |
| PYGL | PYGL | P06737 | Glycogen phosphorylase, liver form | chr14 | GO:0006091 | Not Cancer Driver | No | 98 | 0.116 | 23 | 2 | 0.087 | 2 |
| PYGM | PYGM | P11217 | Glycogen phosphorylase, muscle form | chr11 | GO:0006091 | Not Cancer Driver | No | 153 | 0.182 | 39 | 4 | 0.103 | 17 |
| RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | GO:0006091 | Not Cancer Driver | No | 202 | 0.127 | 578 | 75 | 0.13 | 0 |
| RBKS | RBKS | Q9H477 | Ribokinase | chr2 | GO:0006091 | Not Cancer Driver | No | 27 | 0.084 | 28 | 5 | 0.179 | 0 |
| RPE | RPE | Q96AT9 | Ribulose-phosphate 3-epimerase | chr2 | GO:0006091 | Not Cancer Driver | No | 31 | 0.136 | 28 | 6 | 0.214 | 0 |
| RPEL1 | RPEL1 | Q2QD12 | Ribulose-phosphate 3-epimerase-like protein 1 | chr10 | GO:0006091 | Not Cancer Driver | No | 29 | 0.127 | 44 | 5 | 0.114 | 0 |
| RPIA | RPIA | P49247 | Ribose-5-phosphate isomerase | chr2 | GO:0006091 | Not Cancer Driver | No | 37 | 0.119 | 97 | 4 | 0.041 | 1 |
| SHPK | SHPK | Q9UHJ6 | Sedoheptulokinase | chr17 | GO:0006091 | Not Cancer Driver | No | 44 | 0.092 | 31 | 1 | 0.032 | 0 |
| SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | GO:0006091 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 9 |
| SLC27A5 | SLC27A5 | Q9Y2P5 | Bile acyl-CoA synthetase | chr19 | GO:0006091 | Not Cancer Driver | No | 107 | 0.155 | 7 | 2 | 0.286 | 0 |
| STBD1 | STBD1 | O95210 | Starch-binding domain-containing protein 1 | chr4 | GO:0006091 | Not Cancer Driver | No | 47 | 0.131 | 229 | 31 | 0.135 | 0 |
| TALDO1 | TALDO1 | P37837 | Transaldolase | chr11 | GO:0006091 | Not Cancer Driver | No | 51 | 0.151 | 31 | 4 | 0.129 | 0 |
| THTPA | THTPA | Q9BU02 | Thiamine-triphosphatase | chr14 | GO:0006091 | Not Cancer Driver | No | 19 | 0.083 | 56 | 4 | 0.071 | 0 |
| TKT_ENST00000462138 | TKT | P29401 | Transketolase | chr3 | GO:0006091 | Not Cancer Driver | No | 66 | 0.106 | 86 | 7 | 0.081 | 1 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0006091 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TYRP1 | TYRP1 | P17643 | 5,6-dihydroxyindole-2-carboxylic acid oxidase | chr9 | GO:0006091 | Not Cancer Driver | No | 81 | 0.151 | 87 | 13 | 0.149 | 2 |
| UQCR11 | UQCR11 | O14957 | Cytochrome b-c1 complex subunit 10 | chr19 | GO:0006091 | Not Cancer Driver | No | 7 | 0.125 | 0 | 0 | 0.0 | 0 |
| VGF | VGF | O15240 | Neurosecretory protein VGF | chr7 | GO:0006091 | Not Cancer Driver | No | 48 | 0.078 | 593 | 47 | 0.079 | 0 |
| XYLB | XYLB | O75191 | Xylulose kinase | chr3 | GO:0006091 | Not Cancer Driver | No | 90 | 0.168 | 22 | 4 | 0.182 | 0 |