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Total number of protein in "GO:0006066" GO term:  219

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0006066 Not Cancer Driver No 240 0.099 497 44 0.089 0
ACER1 ACER1 Q8TDN7 Alkaline ceramidase 1 chr19 GO:0006066 Not Cancer Driver No 54 0.205 0 0 0.0 0
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0006066 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACER3 ACER3 Q9NUN7 Alkaline ceramidase 3 chr11 GO:0006066 Not Cancer Driver No 28 0.105 0 0 0.0 1
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 GO:0006066 Not Cancer Driver No 94 0.121 172 19 0.11 5
ACPP_ENST00000336375 ACP3 P15309 Prostatic acid phosphatase chr3 GO:0006066 Not Cancer Driver No 81 0.21 24 5 0.208 0
ACSS1 ACSS1 Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial chr20 GO:0006066 Not Cancer Driver No 79 0.115 76 6 0.079 0
ACSS2_ENST00000360596 ACSS2 Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic chr20 GO:0006066 Not Cancer Driver No 62 0.088 111 6 0.054 0
ADH1A ADH1A P07327 Alcohol dehydrogenase 1A chr4 GO:0006066 Not Cancer Driver No 73 0.195 6 3 0.5 0
ADH1B ADH1B P00325 All-trans-retinol dehydrogenase [NAD(+)] ADH1B chr4 GO:0006066 Not Cancer Driver No 108 0.288 6 4 0.667 0
ADH1C ADH1C P00326 Alcohol dehydrogenase 1C chr4 GO:0006066 Not Cancer Driver No 116 0.309 6 5 0.833 0
ADH4_ENST00000265512 ADH4 P08319 All-trans-retinol dehydrogenase [NAD(+)] ADH4 chr4 GO:0006066 Not Cancer Driver No 49 0.129 5 1 0.2 0
ADH5 ADH5 P11766 Alcohol dehydrogenase class-3 chr4 GO:0006066 Not Cancer Driver No 36 0.096 2 1 0.5 0
ADH6_ENST00000237653 ADH6 P28332 Alcohol dehydrogenase 6 chr4 GO:0006066 Not Cancer Driver No 71 0.193 0 0 0.0 0
ADH7_ENST00000209665 ADH7 P40394 All-trans-retinol dehydrogenase [NAD(+)] ADH7 chr4 GO:0006066 Not Cancer Driver No 74 0.192 15 2 0.133 0
AKR1A1_ENST00000621846 AKR1A1 P14550 Aldo-keto reductase family 1 member A1 chr1 GO:0006066 Not Cancer Driver No 40 0.123 26 4 0.154 0
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 GO:0006066 Not Cancer Driver No 52 0.165 19 1 0.053 0
AKR1B10 AKR1B10 O60218 Aldo-keto reductase family 1 member B10 chr7 GO:0006066 Not Cancer Driver No 58 0.184 28 4 0.143 0
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0006066 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0006066 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0006066 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0006066 Not Cancer Driver No 78 0.241 9 3 0.333 0
AKR1D1 AKR1D1 P51857 Aldo-keto reductase family 1 member D1 chr7 GO:0006066 Not Cancer Driver No 89 0.273 15 3 0.2 5
AKR7A2 AKR7A2 O43488 Aflatoxin B1 aldehyde reductase member 2 chr1 GO:0006066 Not Cancer Driver No 35 0.097 90 3 0.033 0
ALDH1A1 ALDH1A1 P00352 Aldehyde dehydrogenase 1A1 chr9 GO:0006066 Not Cancer Driver No 65 0.13 29 3 0.103 0
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0006066 Not Cancer Driver No 100 0.193 56 13 0.232 0
ALDH1A3 ALDH1A3 P47895 Aldehyde dehydrogenase family 1 member A3 chr15 GO:0006066 Not Cancer Driver No 74 0.145 73 7 0.096 10
ALDH1B1 ALDH1B1 P30837 Aldehyde dehydrogenase X, mitochondrial chr9 GO:0006066 Not Cancer Driver No 94 0.182 54 11 0.204 0
ALDH2 ALDH2 P05091 Aldehyde dehydrogenase, mitochondrial chr12 GO:0006066 Census Yes 60 0.116 44 1 0.023 0
ALDH3A2_ENST00000579855 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 GO:0006066 Not Cancer Driver No 47 0.097 5 2 0.4 26
ALDH3B1 ALDH3B1 P43353 Aldehyde dehydrogenase family 3 member B1 chr11 GO:0006066 Not Cancer Driver No 36 0.077 23 6 0.261 0
ALDH3B2 ALDH3B2 P48448 Aldehyde dehydrogenase family 3 member B2 chr11 GO:0006066 Not Cancer Driver No 71 0.184 17 4 0.235 0
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0006066 Not Cancer Driver No 52 0.113 154 26 0.169 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0006066 Not Cancer Driver No 25 0.079 124 6 0.048 12
ASAH1_ENST00000262097 ASAH1 Q13510 Acid ceramidase chr8 GO:0006066 Not Cancer Driver No 47 0.119 10 3 0.3 14
ASAH2 ASAH2 Q9NR71 Neutral ceramidase chr10 GO:0006066 Not Cancer Driver No 71 0.091 140 24 0.171 0
ASAH2B_ENST00000374006 ASAH2B P0C7U1 Putative inactive neutral ceramidase B chr10 GO:0006066 Not Cancer Driver No 9 0.055 14 1 0.071 0
AWAT2 AWAT2 Q6E213 Acyl-CoA wax alcohol acyltransferase 2 chrX GO:0006066 Not Cancer Driver No 58 0.174 4 0 0.0 0
BCO1 BCO1 Q9HAY6 Beta,beta-carotene 15,15'-dioxygenase chr16 GO:0006066 Not Cancer Driver No 78 0.143 37 5 0.135 1
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 GO:0006066 Not Cancer Driver No 44 0.143 9 0 0.0 0
CACNA1H CACNA1H O95180 Voltage-dependent T-type calcium channel subunit alpha-1H chr16 GO:0006066 Not Cancer Driver No 323 0.137 1045 141 0.135 18
CBR4 CBR4 Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase chr4 GO:0006066 Not Cancer Driver No 15 0.063 4 0 0.0 0
CEL CEL P19835 Bile salt-activated lipase chr9 GO:0006066 Not Cancer Driver No 101 0.134 280 40 0.143 0
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0006066 Not Cancer Driver No 138 0.243 41 2 0.049 0
COQ2_ENST00000647002 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 GO:0006066 Not Cancer Driver No 23 0.062 25 0 0.0 17
COQ3 COQ3 Q9NZJ6 Ubiquinone biosynthesis O-methyltransferase, mitochondrial chr6 GO:0006066 Not Cancer Driver No 47 0.127 22 5 0.227 0
CYP11A1 CYP11A1 P05108 Cholesterol side-chain cleavage enzyme, mitochondrial chr15 GO:0006066 Not Cancer Driver No 92 0.177 27 6 0.222 6
CYP11B1 CYP11B1 P15538 Cytochrome P450 11B1, mitochondrial chr8 GO:0006066 Not Cancer Driver No 177 0.352 7 1 0.143 50
CYP11B2 CYP11B2 P19099 Cytochrome P450 11B2, mitochondrial chr8 GO:0006066 Not Cancer Driver No 148 0.294 6 0 0.0 6
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0006066 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1A2 CYP1A2 P05177 Cytochrome P450 1A2 chr15 GO:0006066 Not Cancer Driver No 93 0.18 23 3 0.13 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0006066 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP27A1 CYP27A1 Q02318 Sterol 26-hydroxylase, mitochondrial chr2 GO:0006066 Not Cancer Driver No 69 0.13 47 11 0.234 7
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0006066 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP2C18 CYP2C18 P33260 Cytochrome P450 2C18 chr10 GO:0006066 Not Cancer Driver No 114 0.233 11 1 0.091 0
CYP2C8 CYP2C8 P10632 Cytochrome P450 2C8 chr10 GO:0006066 Census, Compendium Yes 113 0.231 30 11 0.367 0
CYP2D6_ENST00000645361 CYP2D6 P10635 Cytochrome P450 2D6 chr22 GO:0006066 Not Cancer Driver No 76 0.153 66 8 0.121 0
CYP2R1 CYP2R1 Q6VVX0 Vitamin D 25-hydroxylase chr11 GO:0006066 Not Cancer Driver No 53 0.106 5 1 0.2 1
CYP39A1 CYP39A1 Q9NYL5 24-hydroxycholesterol 7-alpha-hydroxylase chr6 GO:0006066 Not Cancer Driver No 61 0.13 3 0 0.0 0
CYP3A4 CYP3A4 P08684 Cytochrome P450 3A4 chr7 GO:0006066 Not Cancer Driver No 91 0.181 22 2 0.091 1
CYP3A5 CYP3A5 P20815 Cytochrome P450 3A5 chr7 GO:0006066 Not Cancer Driver No 67 0.133 38 5 0.132 0
CYP3A7 CYP3A7 P24462 Cytochrome P450 3A7 chr7 GO:0006066 Not Cancer Driver No 91 0.181 17 6 0.353 0
CYP46A1 CYP46A1 Q9Y6A2 Cholesterol 24-hydroxylase chr14 GO:0006066 Not Cancer Driver No 92 0.184 23 4 0.174 0
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0006066 Not Cancer Driver No 109 0.216 48 8 0.167 0
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0006066 Not Cancer Driver No 125 0.203 71 17 0.239 3
DEGS2 DEGS2 Q6QHC5 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 chr14 GO:0006066 Not Cancer Driver No 43 0.133 0 0 0.0 0
DGAT1 DGAT1 O75907 Diacylglycerol O-acyltransferase 1 chr8 GO:0006066 Not Cancer Driver No 52 0.107 62 0 0.0 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0006066 Not Cancer Driver No 56 0.144 17 2 0.118 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0006066 Not Cancer Driver No 55 0.107 0 0 0.0 6
DHCR7 DHCR7 Q9UBM7 7-dehydrocholesterol reductase chr11 GO:0006066 Not Cancer Driver No 85 0.179 7 1 0.143 53
DHDDS_ENST00000236342 DHDDS Q86SQ9 Dehydrodolichyl diphosphate synthase complex subunit DHDDS chr1 GO:0006066 Not Cancer Driver No 38 0.114 19 1 0.053 1
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0006066 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHRS13 DHRS13 Q6UX07 Dehydrogenase/reductase SDR family member 13 chr17 GO:0006066 Not Cancer Driver No 26 0.069 101 8 0.079 0
DHRS3 DHRS3 O75911 Short-chain dehydrogenase/reductase 3 chr1 GO:0006066 Not Cancer Driver No 33 0.109 0 0 0.0 0
DHRS4 DHRS4 Q9BTZ2 Dehydrogenase/reductase SDR family member 4 chr14 GO:0006066 Not Cancer Driver No 30 0.108 38 4 0.105 0
DHRS7_ENST00000557185 DHRS7 Q9Y394 Dehydrogenase/reductase SDR family member 7 chr14 GO:0006066 Not Cancer Driver No 37 0.109 10 0 0.0 0
DHRS9_ENST00000602501 DHRS9 Q9BPW9 Dehydrogenase/reductase SDR family member 9 chr2 GO:0006066 Not Cancer Driver No 67 0.21 3 0 0.0 0
DPAGT1_ENST00000354202 DPAGT1 Q9H3H5 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase chr11 GO:0006066 Not Cancer Driver No 43 0.105 0 0 0.0 7
DPM1_ENST00000371588 DPM1 O60762 Dolichol-phosphate mannosyltransferase subunit 1 chr20 GO:0006066 Not Cancer Driver No 38 0.146 29 6 0.207 3
DPM2 DPM2 O94777 Dolichol phosphate-mannose biosynthesis regulatory protein chr9 GO:0006066 Not Cancer Driver No 9 0.107 0 0 0.0 1
EBP EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX GO:0006066 Not Cancer Driver No 30 0.13 9 0 0.0 9
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0006066 Not Cancer Driver No 112 0.253 56 19 0.339 6
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0006066 Not Cancer Driver No 18 0.062 183 5 0.027 0
GALK1 GALK1 P51570 Galactokinase chr17 GO:0006066 Not Cancer Driver No 31 0.079 43 5 0.116 11
GALR2 GALR2 O43603 Galanin receptor type 2 chr17 GO:0006066 Not Cancer Driver No 40 0.103 0 0 0.0 0
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0006066 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0006066 Not Cancer Driver No 20 0.08 99 5 0.051 38
GDE1 GDE1 Q9NZC3 Glycerophosphodiester phosphodiesterase 1 chr16 GO:0006066 Not Cancer Driver No 36 0.109 37 1 0.027 0
GDPD1 GDPD1 Q8N9F7 Lysophospholipase D GDPD1 chr17 GO:0006066 Not Cancer Driver No 47 0.15 6 0 0.0 0
GDPD3 GDPD3 Q7L5L3 Lysophospholipase D GDPD3 chr16 GO:0006066 Not Cancer Driver No 50 0.157 12 2 0.167 0
GK GK P32189 Glycerol kinase chrX GO:0006066 Not Cancer Driver No 85 0.152 15 3 0.2 3
GK2 GK2 Q14410 Glycerol kinase 2 chr4 GO:0006066 Not Cancer Driver No 175 0.316 14 3 0.214 0
GK3P GK3P Q14409 Glycerol kinase 3 chr4 GO:0006066 Not Cancer Driver No 9 0.016 17 1 0.059 0
GK5 GK5 Q6ZS86 Putative glycerol kinase 5 chr3 GO:0006066 Not Cancer Driver No 42 0.079 9 1 0.111 0
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 GO:0006066 Not Cancer Driver No 56 0.136 35 5 0.143 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0006066 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPD2_ENST00000438166 GPD2 P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial chr2 GO:0006066 Not Cancer Driver No 88 0.121 67 7 0.104 0
HAO1 HAO1 Q9UJM8 2-Hydroxyacid oxidase 1 chr20 GO:0006066 Not Cancer Driver No 117 0.316 7 2 0.286 0
HSD11B2 HSD11B2 P80365 11-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0006066 Not Cancer Driver No 27 0.067 30 0 0.0 14
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 GO:0006066 Census, Compendium Yes 553 1.336 37 3 0.081 0
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 GO:0006066 Census, Compendium Yes 74 0.164 59 1 0.017 7
IDH3A IDH3A P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial chr15 GO:0006066 Not Cancer Driver No 41 0.112 47 11 0.234 0
IDH3B_ENST00000380843 IDH3B O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial chr20 GO:0006066 Not Cancer Driver No 32 0.083 49 3 0.061 1
IDH3G IDH3G P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial chrX GO:0006066 Not Cancer Driver No 48 0.122 77 9 0.117 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0006066 Not Cancer Driver No 45 0.231 87 23 0.264 0
IMPA1_ENST00000256108 IMPA1 P29218 Inositol monophosphatase 1 chr8 GO:0006066 Not Cancer Driver No 36 0.13 3 0 0.0 0
IMPA2 IMPA2 O14732 Inositol monophosphatase 2 chr18 GO:0006066 Not Cancer Driver No 44 0.153 21 1 0.048 0
IMPAD1 BPNT2 Q9NX62 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase chr8 GO:0006066 Not Cancer Driver No 45 0.125 86 10 0.116 2
INPP1 INPP1 P49441 Inositol polyphosphate 1-phosphatase chr2 GO:0006066 Not Cancer Driver No 44 0.11 23 1 0.043 0
INPP4A INPP4A Q96PE3 Inositol polyphosphate-4-phosphatase type I A chr2 GO:0006066 Not Cancer Driver No 114 0.117 153 20 0.131 0
INPP4B_ENST00000513000 INPP4B O15327 Inositol polyphosphate 4-phosphatase type II chr4 GO:0006066 Not Cancer Driver No 145 0.157 191 36 0.188 0
INPP5A INPP5A Q14642 Inositol polyphosphate-5-phosphatase A chr10 GO:0006066 Not Cancer Driver No 59 0.143 7 4 0.571 0
INPP5B_ENST00000373026 INPP5B P32019 Type II inositol 1,4,5-trisphosphate 5-phosphatase chr1 GO:0006066 Not Cancer Driver No 108 0.109 114 11 0.096 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:0006066 Not Cancer Driver No 43 0.067 272 16 0.059 15
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0006066 Not Cancer Driver No 102 0.101 629 42 0.067 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0006066 Not Cancer Driver No 42 0.094 34 2 0.059 7
IP6K1 IP6K1 Q92551 Inositol hexakisphosphate kinase 1 chr3 GO:0006066 Not Cancer Driver No 50 0.113 216 29 0.134 0
IP6K2 IP6K2 Q9UHH9 Inositol hexakisphosphate kinase 2 chr3 GO:0006066 Not Cancer Driver No 45 0.106 96 10 0.104 0
IP6K3 IP6K3 Q96PC2 Inositol hexakisphosphate kinase 3 chr6 GO:0006066 Not Cancer Driver No 85 0.207 149 34 0.228 0
IPMK IPMK Q8NFU5 Inositol polyphosphate multikinase chr10 GO:0006066 Not Cancer Driver No 50 0.12 108 9 0.083 0
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:0006066 Not Cancer Driver No 55 0.112 43 3 0.07 0
ISYNA1 ISYNA1 Q9NPH2 Inositol-3-phosphate synthase 1 chr19 GO:0006066 Not Cancer Driver No 40 0.072 83 2 0.024 0
ITPK1 ITPK1 Q13572 Inositol-tetrakisphosphate 1-kinase chr14 GO:0006066 Not Cancer Driver No 74 0.179 24 1 0.042 0
ITPKA ITPKA P23677 Inositol-trisphosphate 3-kinase A chr15 GO:0006066 Not Cancer Driver No 28 0.061 216 7 0.032 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0006066 Not Cancer Driver No 148 0.156 719 119 0.166 0
ITPKC ITPKC Q96DU7 Inositol-trisphosphate 3-kinase C chr19 GO:0006066 Not Cancer Driver No 78 0.114 452 38 0.084 0
LEP LEP P41159 Leptin chr7 GO:0006066 Not Cancer Driver No 29 0.174 0 0 0.0 2
LIPE LIPE Q05469 Hormone-sensitive lipase chr19 GO:0006066 Not Cancer Driver No 123 0.114 496 65 0.131 0
LRAT LRAT O95237 Lecithin retinol acyltransferase chr4 GO:0006066 Not Cancer Driver No 54 0.235 2 0 0.0 1
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0006066 Not Cancer Driver No 75 0.154 483 74 0.153 46
MINPP1 MINPP1 Q9UNW1 Multiple inositol polyphosphate phosphatase 1 chr10 GO:0006066 Not Cancer Driver No 52 0.107 46 2 0.043 2
MIOX MIOX Q9UGB7 Inositol oxygenase chr22 GO:0006066 Not Cancer Driver No 48 0.168 21 4 0.19 0
MOGAT1 MOGAT1 Q96PD6 2-acylglycerol O-acyltransferase 1 chr2 GO:0006066 Not Cancer Driver No 40 0.119 16 2 0.125 0
MOGAT2 MOGAT2 Q3SYC2 2-acylglycerol O-acyltransferase 2 chr11 GO:0006066 Not Cancer Driver No 77 0.231 8 1 0.125 0
MOGAT3 MOGAT3 Q86VF5 2-acylglycerol O-acyltransferase 3 chr7 GO:0006066 Not Cancer Driver No 77 0.226 7 2 0.286 0
MOXD1 MOXD1 Q6UVY6 DBH-like monooxygenase protein 1 chr6 GO:0006066 Not Cancer Driver No 99 0.162 29 7 0.241 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0006066 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0006066 Not Cancer Driver No 70 0.109 140 16 0.114 1
MTMR7 MTMR7 Q9Y216 Myotubularin-related protein 7 chr8 GO:0006066 Not Cancer Driver No 98 0.148 160 26 0.163 0
NAAA NAAA Q02083 N-acylethanolamine-hydrolyzing acid amidase chr4 GO:0006066 Not Cancer Driver No 42 0.117 43 3 0.07 0
NAPEPLD NAPEPLD Q6IQ20 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D chr7 GO:0006066 Not Cancer Driver No 55 0.14 76 7 0.092 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0006066 Not Cancer Driver No 85 0.203 23 1 0.043 0
NUDT10_ENST00000356450 NUDT10 Q8NFP7 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha chrX GO:0006066 Not Cancer Driver No 29 0.177 68 8 0.118 0
NUDT11 NUDT11 Q96G61 Diphosphoinositol polyphosphate phosphohydrolase 3-beta chrX GO:0006066 Not Cancer Driver No 30 0.183 65 13 0.2 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 GO:0006066 Not Cancer Driver No 22 0.128 38 5 0.132 0
NUDT4B NUDT4B A0A024RBG1 Diphosphoinositol polyphosphate phosphohydrolase NUDT4B chr1 GO:0006066 Not Cancer Driver No 2 0.011 53 0 0.0 0
NUDT4_ENST00000415493 NUDT4 Q9NZJ9 Diphosphoinositol polyphosphate phosphohydrolase 2 chr12 GO:0006066 Not Cancer Driver No 20 0.111 53 9 0.17 0
NUS1 NUS1 Q96E22 Dehydrodolichyl diphosphate synthase complex subunit NUS1 chr6 GO:0006066 Not Cancer Driver No 21 0.072 13 0 0.0 1
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX GO:0006066 Not Cancer Driver No 151 0.168 126 24 0.19 41
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0006066 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCBD1 PCBD1 P61457 Pterin-4-alpha-carbinolamine dehydratase chr10 GO:0006066 Not Cancer Driver No 8 0.077 7 0 0.0 3
PCBD2_ENST00000254908 PCBD2 Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 chr5 GO:0006066 Not Cancer Driver No 6 0.046 3 0 0.0 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0006066 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0006066 Not Cancer Driver No 91 0.142 139 13 0.094 0
PECR PECR Q9BY49 Peroxisomal trans-2-enoyl-CoA reductase chr2 GO:0006066 Not Cancer Driver No 29 0.096 8 0 0.0 0
PGP PGP A6NDG6 Glycerol-3-phosphate phosphatase chr16 GO:0006066 Not Cancer Driver No 10 0.031 21 0 0.0 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0006066 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLB1 PLB1 Q6P1J6 Phospholipase B1, membrane-associated chr2 GO:0006066 Not Cancer Driver No 223 0.153 399 57 0.143 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0006066 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0006066 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLPP1_ENST00000307259 PLPP1 O14494 Phospholipid phosphatase 1 chr5 GO:0006066 Not Cancer Driver No 28 0.099 27 1 0.037 0
PLPP2_ENST00000434325 PLPP2 O43688 Phospholipid phosphatase 2 chr19 GO:0006066 Not Cancer Driver No 47 0.163 0 0 0.0 0
PLPP3 PLPP3 O14495 Phospholipid phosphatase 3 chr1 GO:0006066 Not Cancer Driver No 48 0.154 10 1 0.1 0
PNLIP PNLIP P16233 Pancreatic triacylglycerol lipase chr10 GO:0006066 Not Cancer Driver No 124 0.267 32 11 0.344 1
PNPLA2 PNPLA2 Q96AD5 Patatin-like phospholipase domain-containing protein 2 chr11 GO:0006066 Not Cancer Driver No 35 0.069 101 4 0.04 1
PNPLA4_ENST00000444736 PNPLA4 P41247 Patatin-like phospholipase domain-containing protein 4 chrX GO:0006066 Not Cancer Driver No 41 0.162 3 0 0.0 0
PPIP5K1 PPIP5K1 Q6PFW1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 chr15 GO:0006066 Not Cancer Driver No 58 0.04 544 25 0.046 0
PPIP5K2_ENST00000358359 PPIP5K2 O43314 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 chr5 GO:0006066 Not Cancer Driver No 146 0.117 419 54 0.129 1
PRKG2 PRKG2 Q13237 cGMP-dependent protein kinase 2 chr4 GO:0006066 Not Cancer Driver No 138 0.181 217 48 0.221 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0006066 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0006066 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTS PTS Q03393 6-pyruvoyl tetrahydrobiopterin synthase chr11 GO:0006066 Not Cancer Driver No 9 0.062 22 1 0.045 24
QDPR QDPR P09417 Dihydropteridine reductase chr4 GO:0006066 Not Cancer Driver No 41 0.168 25 3 0.12 16
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 GO:0006066 Not Cancer Driver No 30 0.149 8 1 0.125 4
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0006066 Not Cancer Driver No 33 0.097 8 0 0.0 0
RDH11 RDH11 Q8TC12 Retinol dehydrogenase 11 chr14 GO:0006066 Not Cancer Driver No 25 0.079 2 0 0.0 0
RDH12_ENST00000267502 RDH12 Q96NR8 Retinol dehydrogenase 12 chr14 GO:0006066 Not Cancer Driver No 41 0.13 0 0 0.0 10
RDH13 RDH13 Q8NBN7 Retinol dehydrogenase 13 chr19 GO:0006066 Not Cancer Driver No 42 0.127 48 7 0.146 0
RDH14 RDH14 Q9HBH5 Retinol dehydrogenase 14 chr2 GO:0006066 Not Cancer Driver No 22 0.065 21 0 0.0 0
RDH16 RDH16 O75452 Retinol dehydrogenase 16 chr12 GO:0006066 Not Cancer Driver No 46 0.145 0 0 0.0 0
RDH5_ENST00000548082 RDH5 Q92781 Retinol dehydrogenase 5 chr12 GO:0006066 Not Cancer Driver No 39 0.123 0 0 0.0 18
RETSAT RETSAT Q6NUM9 All-trans-retinol 13,14-reductase chr2 GO:0006066 Not Cancer Driver No 98 0.161 25 5 0.2 0
RPE65 RPE65 Q16518 Retinoid isomerohydrolase chr1 GO:0006066 Not Cancer Driver No 109 0.205 10 1 0.1 44
SC5D_ENST00000392789 SC5D O75845 Lathosterol oxidase chr11 GO:0006066 Not Cancer Driver No 43 0.144 21 3 0.143 3
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0006066 Not Cancer Driver No 53 0.096 6 1 0.167 0
SCARF1 SCARF1 Q14162 Scavenger receptor class F member 1 chr17 GO:0006066 Not Cancer Driver No 90 0.108 340 61 0.179 0
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0006066 Not Cancer Driver No 90 0.141 62 4 0.065 13
SDR16C5_ENST00000303749 SDR16C5 Q8N3Y7 Epidermal retinol dehydrogenase 2 chr8 GO:0006066 Not Cancer Driver No 81 0.262 4 0 0.0 0
SGPP1 SGPP1 Q9BX95 Sphingosine-1-phosphate phosphatase 1 chr14 GO:0006066 Not Cancer Driver No 48 0.109 116 1 0.009 0
SGPP2 SGPP2 Q8IWX5 Sphingosine-1-phosphate phosphatase 2 chr2 GO:0006066 Not Cancer Driver No 44 0.11 42 0 0.0 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0006066 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC5A3 SLC5A3 P53794 Sodium/myo-inositol cotransporter chr21 GO:0006066 Not Cancer Driver No 81 0.113 73 6 0.082 0
SNX17 SNX17 Q15036 Sorting nexin-17 chr2 GO:0006066 Not Cancer Driver No 55 0.117 118 10 0.085 0
SORD SORD Q00796 Sorbitol dehydrogenase chr15 GO:0006066 Not Cancer Driver No 29 0.081 41 7 0.171 3
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0006066 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0006066 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPR SPR P35270 Sepiapterin reductase chr2 GO:0006066 Not Cancer Driver No 23 0.088 19 4 0.211 2
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 GO:0006066 Not Cancer Driver No 50 0.106 27 5 0.185 5
SPTLC2 SPTLC2 O15270 Serine palmitoyltransferase 2 chr14 GO:0006066 Not Cancer Driver No 72 0.128 9 2 0.222 5
SPTLC3 SPTLC3 Q9NUV7 Serine palmitoyltransferase 3 chr20 GO:0006066 Not Cancer Driver No 135 0.245 40 12 0.3 0
SPTSSA SPTSSA Q969W0 Serine palmitoyltransferase small subunit A chr14 GO:0006066 Not Cancer Driver No 9 0.127 0 0 0.0 0
SPTSSB_ENST00000620149 SPTSSB Q8NFR3 Serine palmitoyltransferase small subunit B chr3 GO:0006066 Not Cancer Driver No 15 0.197 0 0 0.0 0
SRD5A3 SRD5A3 Q9H8P0 Polyprenol reductase chr4 GO:0006066 Not Cancer Driver No 35 0.11 0 0 0.0 0
SULT1A1_ENST00000314752 SULT1A1 P50225 Sulfotransferase 1A1 chr16 GO:0006066 Not Cancer Driver No 69 0.234 14 3 0.214 0
SULT1A2 SULT1A2 P50226 Sulfotransferase 1A2 chr16 GO:0006066 Not Cancer Driver No 46 0.156 3 0 0.0 0
SULT1B1 SULT1B1 O43704 Sulfotransferase 1B1 chr4 GO:0006066 Not Cancer Driver No 82 0.277 15 7 0.467 0
SULT1C4 SULT1C4 O75897 Sulfotransferase 1C4 chr2 GO:0006066 Not Cancer Driver No 57 0.189 19 5 0.263 0
SULT1E1 SULT1E1 P49888 Sulfotransferase 1E1 chr4 GO:0006066 Not Cancer Driver No 76 0.259 15 5 0.333 0
SULT2A1 SULT2A1 Q06520 Sulfotransferase 2A1 chr19 GO:0006066 Not Cancer Driver No 50 0.175 0 0 0.0 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0006066 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0006066 Not Cancer Driver No 189 0.126 545 70 0.128 0
THTPA THTPA Q9BU02 Thiamine-triphosphatase chr14 GO:0006066 Not Cancer Driver No 19 0.083 56 4 0.071 0
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 GO:0006066 Not Cancer Driver No 66 0.115 91 14 0.154 2
TKTL1 TKTL1 P51854 Transketolase-like protein 1 chrX GO:0006066 Not Cancer Driver No 94 0.158 88 16 0.182 0
TPI1_ENST00000396705 TPI1 P60174 Triosephosphate isomerase chr12 GO:0006066 Not Cancer Driver No 40 0.161 15 2 0.133 7
TPK1 TPK1 Q9H3S4 Thiamin pyrophosphokinase 1 chr7 GO:0006066 Not Cancer Driver No 56 0.23 0 0 0.0 3
TTR TTR P02766 Transthyretin chr18 GO:0006066 Not Cancer Driver No 28 0.19 25 8 0.32 75
UGT1A3 UGT1A3 P35503 UDP-glucuronosyltransferase 1A3 chr2 GO:0006066 Not Cancer Driver No 98 0.184 11 2 0.182 0
UGT1A4 UGT1A4 P22310 UDP-glucuronosyltransferase 1A4 chr2 GO:0006066 Not Cancer Driver No 99 0.185 11 2 0.182 0