Total number of protein in "GO:0006006" GO term: 98
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0006006 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
| ADPGK | ADPGK | Q9BRR6 | ADP-dependent glucokinase | chr15 | GO:0006006 | Not Cancer Driver | No | 38 | 0.076 | 24 | 0 | 0.0 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0006006 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | GO:0006006 | Census | Yes | 77 | 0.16 | 84 | 9 | 0.107 | 2 |
| APOD | APOD | P05090 | Apolipoprotein D | chr3 | GO:0006006 | Not Cancer Driver | No | 34 | 0.18 | 13 | 2 | 0.154 | 0 |
| ATF3_ENST00000366987 | ATF3 | P18847 | Cyclic AMP-dependent transcription factor ATF-3 | chr1 | GO:0006006 | Not Cancer Driver | No | 23 | 0.127 | 118 | 14 | 0.119 | 0 |
| ATF4_ENST00000404241 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0006006 | Not Cancer Driver | No | 53 | 0.151 | 259 | 38 | 0.147 | 0 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0006006 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BRAT1 | BRAT1 | Q6PJG6 | BRCA1-associated ATM activator 1 | chr7 | GO:0006006 | Not Cancer Driver | No | 112 | 0.136 | 101 | 13 | 0.129 | 0 |
| BRS3 | BRS3 | P32247 | Bombesin receptor subtype-3 | chrX | GO:0006006 | Not Cancer Driver | No | 72 | 0.18 | 32 | 8 | 0.25 | 0 |
| CPT1A_ENST00000539743 | CPT1A | P50416 | Carnitine O-palmitoyltransferase 1, liver isoform | chr11 | GO:0006006 | Not Cancer Driver | No | 144 | 0.186 | 62 | 10 | 0.161 | 15 |
| CRTC2 | CRTC2 | Q53ET0 | CREB-regulated transcription coactivator 2 | chr1 | GO:0006006 | Not Cancer Driver | No | 92 | 0.133 | 674 | 88 | 0.131 | 0 |
| CRY1 | CRY1 | Q16526 | Cryptochrome-1 | chr12 | GO:0006006 | Not Cancer Driver | No | 76 | 0.13 | 91 | 5 | 0.055 | 0 |
| DCXR | DCXR | Q7Z4W1 | L-xylulose reductase | chr17 | GO:0006006 | Not Cancer Driver | No | 14 | 0.057 | 10 | 1 | 0.1 | 0 |
| DLAT | DLAT | P10515 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | chr11 | GO:0006006 | Not Cancer Driver | No | 63 | 0.097 | 294 | 42 | 0.143 | 0 |
| ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | GO:0006006 | Not Cancer Driver | No | 51 | 0.118 | 21 | 2 | 0.095 | 0 |
| ENO2 | ENO2 | P09104 | Gamma-enolase | chr12 | GO:0006006 | Not Cancer Driver | No | 48 | 0.111 | 12 | 2 | 0.167 | 0 |
| FABP5 | FABP5 | Q01469 | Fatty acid-binding protein 5 | chr8 | GO:0006006 | Not Cancer Driver | No | 15 | 0.111 | 4 | 4 | 1.0 | 0 |
| FBP1_ENST00000375326 | FBP1 | P09467 | Fructose-1,6-bisphosphatase 1 | chr9 | GO:0006006 | Not Cancer Driver | No | 33 | 0.098 | 19 | 0 | 0.0 | 4 |
| FBP2 | FBP2 | O00757 | Fructose-1,6-bisphosphatase isozyme 2 | chr9 | GO:0006006 | Not Cancer Driver | No | 54 | 0.159 | 15 | 3 | 0.2 | 0 |
| FOXK1 | FOXK1 | P85037 | Forkhead box protein K1 | chr7 | GO:0006006 | Not Cancer Driver | No | 97 | 0.132 | 511 | 65 | 0.127 | 0 |
| FOXK2 | FOXK2 | Q01167 | Forkhead box protein K2 | chr17 | GO:0006006 | Not Cancer Driver | No | 79 | 0.12 | 548 | 64 | 0.117 | 0 |
| G6PC | G6PC1 | P35575 | Glucose-6-phosphatase catalytic subunit 1 | chr17 | GO:0006006 | Not Cancer Driver | No | 67 | 0.188 | 0 | 0 | 0.0 | 54 |
| G6PC2 | G6PC2 | Q9NQR9 | Glucose-6-phosphatase 2 | chr2 | GO:0006006 | Not Cancer Driver | No | 68 | 0.192 | 0 | 0 | 0.0 | 0 |
| G6PC3 | G6PC3 | Q9BUM1 | Glucose-6-phosphatase 3 | chr17 | GO:0006006 | Not Cancer Driver | No | 21 | 0.061 | 2 | 0 | 0.0 | 21 |
| G6PD_ENST00000621232 | G6PD | P11413 | Glucose-6-phosphate 1-dehydrogenase | chrX | GO:0006006 | Not Cancer Driver | No | 86 | 0.167 | 28 | 3 | 0.107 | 58 |
| GAA_ENST00000390015 | GAA | P10253 | Lysosomal alpha-glucosidase | chr17 | GO:0006006 | Not Cancer Driver | No | 101 | 0.106 | 147 | 18 | 0.122 | 131 |
| GALM | GALM | Q96C23 | Galactose mutarotase | chr2 | GO:0006006 | Not Cancer Driver | No | 31 | 0.091 | 35 | 2 | 0.057 | 1 |
| GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | GO:0006006 | Not Cancer Driver | No | 39 | 0.116 | 24 | 3 | 0.125 | 0 |
| GAPDHS | GAPDHS | O14556 | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | chr19 | GO:0006006 | Not Cancer Driver | No | 71 | 0.174 | 111 | 19 | 0.171 | 0 |
| GCK_ENST00000403799 | GCK | P35557 | Hexokinase-4 | chr7 | GO:0006006 | Not Cancer Driver | No | 88 | 0.189 | 73 | 14 | 0.192 | 107 |
| GDPGP1 | GDPGP1 | Q6ZNW5 | GDP-D-glucose phosphorylase 1 | chr15 | GO:0006006 | Not Cancer Driver | No | 44 | 0.114 | 83 | 9 | 0.108 | 0 |
| GHRL_ENST00000457360 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0006006 | Not Cancer Driver | No | 20 | 0.171 | 52 | 11 | 0.212 | 0 |
| GPD1 | GPD1 | P21695 | Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic | chr12 | GO:0006006 | Not Cancer Driver | No | 59 | 0.169 | 2 | 0 | 0.0 | 1 |
| GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | GO:0006006 | Not Cancer Driver | No | 77 | 0.138 | 73 | 11 | 0.151 | 24 |
| H6PD_ENST00000377403 | H6PD | O95479 | GDH/6PGL endoplasmic bifunctional protein | chr1 | GO:0006006 | Not Cancer Driver | No | 96 | 0.121 | 39 | 3 | 0.077 | 2 |
| HK1_ENST00000359426 | HK1 | P19367 | Hexokinase-1 | chr10 | GO:0006006 | Not Cancer Driver | No | 127 | 0.138 | 75 | 16 | 0.213 | 6 |
| HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:0006006 | Not Cancer Driver | No | 138 | 0.15 | 77 | 7 | 0.091 | 0 |
| HK3 | HK3 | P52790 | Hexokinase-3 | chr5 | GO:0006006 | Not Cancer Driver | No | 164 | 0.178 | 71 | 17 | 0.239 | 0 |
| IGF2_ENST00000641326 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0006006 | Not Cancer Driver | No | 39 | 0.217 | 44 | 12 | 0.273 | 0 |
| INPPL1 | INPPL1 | O15357 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | chr11 | GO:0006006 | Not Cancer Driver | No | 174 | 0.138 | 566 | 76 | 0.134 | 4 |
| INS | INS | P01308 | Insulin | chr11 | GO:0006006 | Not Cancer Driver | No | 15 | 0.136 | 5 | 1 | 0.2 | 22 |
| IRS2 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | GO:0006006 | Not Cancer Driver | No | 69 | 0.052 | 1112 | 57 | 0.051 | 0 |
| KBTBD2 | KBTBD2 | Q8IY47 | Kelch repeat and BTB domain-containing protein 2 | chr7 | GO:0006006 | Not Cancer Driver | No | 72 | 0.116 | 25 | 4 | 0.16 | 0 |
| KCNJ11 | KCNJ11 | Q14654 | ATP-sensitive inward rectifier potassium channel 11 | chr11 | GO:0006006 | Not Cancer Driver | No | 48 | 0.123 | 19 | 3 | 0.158 | 46 |
| KCNQ1 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0006006 | Not Cancer Driver | No | 78 | 0.115 | 219 | 20 | 0.091 | 132 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0006006 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LRP5 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0006006 | Not Cancer Driver | No | 253 | 0.157 | 188 | 28 | 0.149 | 55 |
| MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0006006 | Not Cancer Driver | No | 39 | 0.108 | 25 | 1 | 0.04 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0006006 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| NPY1R | NPY1R | P25929 | Neuropeptide Y receptor type 1 | chr4 | GO:0006006 | Not Cancer Driver | No | 114 | 0.297 | 4 | 0 | 0.0 | 0 |
| OAS1_ENST00000202917 | OAS1 | P00973 | 2'-5'-oligoadenylate synthase 1 | chr12 | GO:0006006 | Not Cancer Driver | No | 67 | 0.168 | 71 | 12 | 0.169 | 0 |
| OMA1 | OMA1 | Q96E52 | Metalloendopeptidase OMA1, mitochondrial | chr1 | GO:0006006 | Not Cancer Driver | No | 52 | 0.099 | 34 | 4 | 0.118 | 0 |
| ONECUT1 | ONECUT1 | Q9UBC0 | Hepatocyte nuclear factor 6 | chr15 | GO:0006006 | Not Cancer Driver | No | 78 | 0.168 | 405 | 65 | 0.16 | 0 |
| PC | PC | P11498 | Pyruvate carboxylase, mitochondrial | chr11 | GO:0006006 | Not Cancer Driver | No | 185 | 0.157 | 172 | 27 | 0.157 | 9 |
| PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0006006 | Not Cancer Driver | No | 142 | 0.228 | 110 | 28 | 0.255 | 1 |
| PCK2 | PCK2 | Q16822 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | chr14 | GO:0006006 | Not Cancer Driver | No | 91 | 0.142 | 139 | 13 | 0.094 | 0 |
| PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | GO:0006006 | Not Cancer Driver | No | 70 | 0.179 | 43 | 6 | 0.14 | 20 |
| PDHA2 | PDHA2 | P29803 | Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial | chr4 | GO:0006006 | Not Cancer Driver | No | 163 | 0.42 | 41 | 17 | 0.415 | 0 |
| PDHB | PDHB | P11177 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | chr3 | GO:0006006 | Not Cancer Driver | No | 32 | 0.089 | 4 | 0 | 0.0 | 2 |
| PDK1_ENST00000282077 | PDK1 | Q15118 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | chr2 | GO:0006006 | Not Cancer Driver | No | 52 | 0.119 | 50 | 10 | 0.2 | 0 |
| PDK2 | PDK2 | Q15119 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | chr17 | GO:0006006 | Not Cancer Driver | No | 45 | 0.111 | 35 | 4 | 0.114 | 0 |
| PDK3_ENST00000379162 | PDK3 | Q15120 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial | chrX | GO:0006006 | Not Cancer Driver | No | 61 | 0.15 | 28 | 6 | 0.214 | 1 |
| PDK4 | PDK4 | Q16654 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | chr7 | GO:0006006 | Not Cancer Driver | No | 70 | 0.17 | 14 | 2 | 0.143 | 0 |
| PDX1 | PDX1 | P52945 | Pancreas/duodenum homeobox protein 1 | chr13 | GO:0006006 | Not Cancer Driver | No | 32 | 0.113 | 238 | 23 | 0.097 | 0 |
| PER2 | PER2 | O15055 | Period circadian protein homolog 2 | chr2 | GO:0006006 | Not Cancer Driver | No | 166 | 0.132 | 782 | 101 | 0.129 | 1 |
| PFKFB1 | PFKFB1 | P16118 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 | chrX | GO:0006006 | Not Cancer Driver | No | 81 | 0.172 | 48 | 11 | 0.229 | 0 |
| PFKFB2 | PFKFB2 | O60825 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 | chr1 | GO:0006006 | Not Cancer Driver | No | 68 | 0.135 | 97 | 18 | 0.186 | 0 |
| PFKL | PFKL | P17858 | ATP-dependent 6-phosphofructokinase, liver type | chr21 | GO:0006006 | Not Cancer Driver | No | 91 | 0.117 | 29 | 4 | 0.138 | 0 |
| PFKM_ENST00000550924 | PFKM | P08237 | ATP-dependent 6-phosphofructokinase, muscle type | chr12 | GO:0006006 | Not Cancer Driver | No | 80 | 0.103 | 70 | 8 | 0.114 | 9 |
| PFKP | PFKP | Q01813 | ATP-dependent 6-phosphofructokinase, platelet type | chr10 | GO:0006006 | Not Cancer Driver | No | 133 | 0.17 | 43 | 10 | 0.233 | 0 |
| PGAM2 | PGAM2 | P15259 | Phosphoglycerate mutase 2 | chr7 | GO:0006006 | Not Cancer Driver | No | 46 | 0.182 | 81 | 14 | 0.173 | 3 |
| PGK1 | PGK1 | P00558 | Phosphoglycerate kinase 1 | chrX | GO:0006006 | Not Cancer Driver | No | 61 | 0.146 | 40 | 5 | 0.125 | 9 |
| PGK2 | PGK2 | P07205 | Phosphoglycerate kinase 2 | chr6 | GO:0006006 | Not Cancer Driver | No | 145 | 0.348 | 37 | 13 | 0.351 | 0 |
| PGM1_ENST00000371084 | PGM1 | P36871 | Phosphoglucomutase-1 | chr1 | GO:0006006 | Not Cancer Driver | No | 62 | 0.11 | 31 | 3 | 0.097 | 13 |
| PGM2 | PGM2 | Q96G03 | Phosphopentomutase | chr4 | GO:0006006 | Not Cancer Driver | No | 79 | 0.129 | 108 | 13 | 0.12 | 0 |
| PGM2L1 | PGM2L1 | Q6PCE3 | Glucose 1,6-bisphosphate synthase | chr11 | GO:0006006 | Not Cancer Driver | No | 62 | 0.1 | 66 | 6 | 0.091 | 0 |
| PGM5 | PGM5 | Q15124 | Phosphoglucomutase-like protein 5 | chr9 | GO:0006006 | Not Cancer Driver | No | 165 | 0.291 | 54 | 4 | 0.074 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0006006 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | GO:0006006 | Not Cancer Driver | No | 72 | 0.163 | 69 | 7 | 0.101 | 0 |
| PPARGC1A | PPARGC1A | Q9UBK2 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | chr4 | GO:0006006 | Not Cancer Driver | No | 181 | 0.227 | 609 | 148 | 0.243 | 0 |
| PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0006006 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
| RBP4 | RBP4 | P02753 | Retinol-binding protein 4 | chr10 | GO:0006006 | Not Cancer Driver | No | 30 | 0.149 | 8 | 1 | 0.125 | 4 |
| SDS | SDS | P20132 | L-serine dehydratase/L-threonine deaminase | chr12 | GO:0006006 | Not Cancer Driver | No | 40 | 0.122 | 17 | 1 | 0.059 | 0 |
| SERP1_ENST00000239944 | SERP1 | Q9Y6X1 | Stress-associated endoplasmic reticulum protein 1 | chr3 | GO:0006006 | Not Cancer Driver | No | 6 | 0.091 | 30 | 2 | 0.067 | 0 |
| SLC25A1 | SLC25A1 | P53007 | Tricarboxylate transport protein, mitochondrial | chr22 | GO:0006006 | Not Cancer Driver | No | 22 | 0.071 | 34 | 2 | 0.059 | 17 |
| SLC25A10_ENST00000350690 | SLC25A10 | Q9UBX3 | Mitochondrial dicarboxylate carrier | chr17 | GO:0006006 | Not Cancer Driver | No | 33 | 0.115 | 0 | 0 | 0.0 | 0 |
| SLC25A12 | SLC25A12 | O75746 | Calcium-binding mitochondrial carrier protein Aralar1 | chr2 | GO:0006006 | Not Cancer Driver | No | 110 | 0.162 | 21 | 7 | 0.333 | 2 |
| SLC25A13_ENST00000265631 | SLC25A13 | Q9UJS0 | Calcium-binding mitochondrial carrier protein Aralar2 | chr7 | GO:0006006 | Not Cancer Driver | No | 111 | 0.164 | 23 | 2 | 0.087 | 1 |
| SLC37A4_ENST00000545985 | SLC37A4 | O43826 | Glucose-6-phosphate exchanger SLC37A4 | chr11 | GO:0006006 | Not Cancer Driver | No | 41 | 0.096 | 17 | 1 | 0.059 | 32 |
| SLC39A14_ENST00000381237 | SLC39A14 | Q15043 | Metal cation symporter ZIP14 | chr8 | GO:0006006 | Not Cancer Driver | No | 34 | 0.069 | 42 | 3 | 0.071 | 4 |
| SORD | SORD | Q00796 | Sorbitol dehydrogenase | chr15 | GO:0006006 | Not Cancer Driver | No | 29 | 0.081 | 41 | 7 | 0.171 | 3 |
| TFAP2B | TFAP2B | Q92481 | Transcription factor AP-2-beta | chr6 | GO:0006006 | Not Cancer Driver | No | 114 | 0.248 | 306 | 75 | 0.245 | 6 |
| TKTL1 | TKTL1 | P51854 | Transketolase-like protein 1 | chrX | GO:0006006 | Not Cancer Driver | No | 94 | 0.158 | 88 | 16 | 0.182 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0006006 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TPI1_ENST00000396705 | TPI1 | P60174 | Triosephosphate isomerase | chr12 | GO:0006006 | Not Cancer Driver | No | 40 | 0.161 | 15 | 2 | 0.133 | 7 |
| TSTD1 | TSTD1 | Q8NFU3 | Thiosulfate:glutathione sulfurtransferase | chr1 | GO:0006006 | Not Cancer Driver | No | 4 | 0.035 | 4 | 0 | 0.0 | 0 |
| WDTC1 | WDTC1 | Q8N5D0 | WD and tetratricopeptide repeats protein 1 | chr1 | GO:0006006 | Not Cancer Driver | No | 81 | 0.12 | 154 | 21 | 0.136 | 0 |