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Total number of protein in "GO:0005911" GO term:  276

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0005911 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 GO:0005911 Not Cancer Driver No 243 0.189 74 14 0.189 72
ABCC2 ABCC2 Q92887 ATP-binding cassette sub-family C member 2 chr10 GO:0005911 Not Cancer Driver No 202 0.131 102 23 0.225 4
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0005911 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0005911 Not Cancer Driver No 73 0.195 42 10 0.238 16
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 GO:0005911 Not Cancer Driver No 108 0.121 195 30 0.154 6
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 GO:0005911 Not Cancer Driver No 32 0.077 16 2 0.125 0
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0005911 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADD3 ADD3 Q9UEY8 Gamma-adducin chr10 GO:0005911 Not Cancer Driver No 95 0.135 381 48 0.126 1
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0005911 Compendium Yes 213 0.134 485 47 0.097 0
ADGRL3 ADGRL3 Q9HAR2 Adhesion G protein-coupled receptor L3 chr4 GO:0005911 Not Cancer Driver No 440 0.304 517 130 0.251 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 GO:0005911 Census Yes 248 0.136 1247 180 0.144 0
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0005911 Not Cancer Driver No 120 0.1 500 56 0.112 6
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 GO:0005911 Compendium Yes 45 0.084 307 13 0.042 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0005911 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0005911 Census, Compendium Yes 108 0.225 158 24 0.152 4
AMTN AMTN Q6UX39 Amelotin chr4 GO:0005911 Not Cancer Driver No 39 0.187 126 28 0.222 0
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0005911 Not Cancer Driver No 770 0.195 2844 566 0.199 4
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0005911 Not Cancer Driver No 860 0.196 3054 579 0.19 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0005911 Not Cancer Driver No 128 0.166 418 71 0.17 17
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0005911 Not Cancer Driver No 34 0.116 12 0 0.0 0
AQP7 AQP7 O14520 Aquaporin-7 chr9 GO:0005911 Not Cancer Driver No 61 0.178 29 2 0.069 0
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0005911 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 GO:0005911 Not Cancer Driver No 38 0.125 55 9 0.164 0
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0005911 Not Cancer Driver No 38 0.095 129 13 0.101 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0005911 Not Cancer Driver No 106 0.24 103 28 0.272 0
CADM3_ENST00000368125 CADM3 Q8N126 Cell adhesion molecule 3 chr1 GO:0005911 Not Cancer Driver No 120 0.302 170 65 0.382 0
CALB2 CALB2 P22676 Calretinin chr16 GO:0005911 Not Cancer Driver No 54 0.199 39 8 0.205 0
CAMSAP3_ENST00000160298 CAMSAP3 Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 chr19 GO:0005911 Not Cancer Driver No 132 0.106 889 81 0.091 0
CASK_ENST00000378163 CASK O14936 Peripheral plasma membrane protein CASK chrX GO:0005911 Not Cancer Driver No 118 0.127 285 45 0.158 4
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0005911 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0005911 Not Cancer Driver No 66 0.185 19 1 0.053 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0005911 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0005911 Not Cancer Driver No 80 0.125 456 60 0.132 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0005911 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD53 CD53 P19397 Leukocyte surface antigen CD53 chr1 GO:0005911 Not Cancer Driver No 43 0.196 0 0 0.0 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 GO:0005911 Not Cancer Driver No 215 0.124 717 80 0.112 0
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 GO:0005911 Not Cancer Driver No 185 0.108 696 92 0.132 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0005911 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0005911 Not Cancer Driver No 238 0.263 461 130 0.282 7
CDH24_ENST00000267383 CDH24 Q86UP0 Cadherin-24 chr14 GO:0005911 Not Cancer Driver No 84 0.103 439 47 0.107 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0005911 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDSN CDSN Q15517 Corneodesmosin chr6 GO:0005911 Not Cancer Driver No 56 0.106 469 52 0.111 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0005911 Not Cancer Driver No 64 0.122 241 25 0.104 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0005911 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN11 CLDN11 O75508 Claudin-11 chr3 GO:0005911 Not Cancer Driver No 30 0.145 0 0 0.0 0
CLDN20 CLDN20 P56880 Claudin-20 chr6 GO:0005911 Not Cancer Driver No 21 0.096 19 3 0.158 0
CLDN25 CLDN25 C9JDP6 Putative claudin-25 chr11 GO:0005911 Not Cancer Driver No 38 0.166 0 0 0.0 0
CLDN2_ENST00000336803 CLDN2 P57739 Claudin-2 chrX GO:0005911 Not Cancer Driver No 33 0.143 13 0 0.0 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0005911 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0005911 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0005911 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 GO:0005911 Not Cancer Driver No 24 0.095 49 4 0.082 0
CNKSR1 CNKSR1 Q969H4 Connector enhancer of kinase suppressor of ras 1 chr1 GO:0005911 Not Cancer Driver No 118 0.164 405 68 0.168 0
CNN2_ENST00000263097 CNN2 Q99439 Calponin-2 chr19 GO:0005911 Not Cancer Driver No 35 0.113 166 23 0.139 0
CNTNAP1 CNTNAP1 P78357 Contactin-associated protein 1 chr17 GO:0005911 Not Cancer Driver No 173 0.125 141 15 0.106 6
CNTNAP2 CNTNAP2 Q9UHC6 Contactin-associated protein-like 2 chr7 GO:0005911 Census Yes 570 0.428 161 82 0.509 0
COL13A1 COL13A1 Q5TAT6 Collagen alpha-1(XIII) chain chr10 GO:0005911 Not Cancer Driver No 126 0.176 690 126 0.183 0
COL17A1 COL17A1 Q9UMD9 Collagen alpha-1(XVII) chain chr10 GO:0005911 Not Cancer Driver No 196 0.131 1275 164 0.129 5
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0005911 Not Cancer Driver No 51 0.111 126 15 0.119 1
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0005911 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0005911 Census Yes 126 0.139 268 35 0.131 4
CTNNA3 CTNNA3 Q9UI47 Catenin alpha-3 chr10 GO:0005911 Not Cancer Driver No 269 0.301 186 50 0.269 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0005911 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNND1 CTNND1 O60716 Catenin delta-1 chr11 GO:0005911 Census Yes 154 0.159 570 83 0.146 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 GO:0005911 Not Cancer Driver No 51 0.14 98 19 0.194 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0005911 Not Cancer Driver No 84 0.129 510 73 0.143 0
DES DES P17661 Desmin chr2 GO:0005911 Not Cancer Driver No 71 0.151 264 41 0.155 35
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0005911 Not Cancer Driver No 120 0.133 460 67 0.146 0
DNMBP DNMBP Q6XZF7 Dynamin-binding protein chr10 GO:0005911 Not Cancer Driver No 208 0.132 758 92 0.121 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0005911 Not Cancer Driver No 151 0.197 8 1 0.125 0
DSC1 DSC1 Q08554 Desmocollin-1 chr18 GO:0005911 Not Cancer Driver No 219 0.245 265 65 0.245 0
DSC2 DSC2 Q02487 Desmocollin-2 chr18 GO:0005911 Not Cancer Driver No 192 0.213 257 61 0.237 5
DSC3 DSC3 Q14574 Desmocollin-3 chr18 GO:0005911 Not Cancer Driver No 204 0.228 213 57 0.268 0
DSG1 DSG1 Q02413 Desmoglein-1 chr18 GO:0005911 Not Cancer Driver No 250 0.238 496 130 0.262 0
DSG2 DSG2 Q14126 Desmoglein-2 chr18 GO:0005911 Not Cancer Driver No 173 0.155 476 68 0.143 5
DSG3 DSG3 P32926 Desmoglein-3 chr18 GO:0005911 Not Cancer Driver No 270 0.27 264 64 0.242 0
DSG4_ENST00000308128 DSG4 Q86SJ6 Desmoglein-4 chr18 GO:0005911 Not Cancer Driver No 275 0.264 186 44 0.237 0
DSP DSP P15924 Desmoplakin chr6 GO:0005911 Not Cancer Driver No 483 0.168 1124 204 0.181 6
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0005911 Not Cancer Driver No 104 0.114 284 33 0.116 0
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 GO:0005911 Not Cancer Driver No 298 0.274 695 207 0.298 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0005911 Compendium Yes 171 0.175 187 39 0.209 3
ESAM ESAM Q96AP7 Endothelial cell-selective adhesion molecule chr11 GO:0005911 Not Cancer Driver No 54 0.138 154 30 0.195 0
EVPL_ENST00000301607 EVPL Q92817 Envoplakin chr17 GO:0005911 Not Cancer Driver No 290 0.143 1222 169 0.138 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0005911 Not Cancer Driver No 47 0.157 72 15 0.208 0
FAT1 FAT1 Q14517 Protocadherin Fat 1 chr4 GO:0005911 Census, Compendium Yes 663 0.145 1051 126 0.12 0
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0005911 Not Cancer Driver No 70 0.286 96 33 0.344 2
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0005911 Census, Compendium Yes 113 0.141 162 28 0.173 0
FHOD1 FHOD1 Q9Y613 FH1/FH2 domain-containing protein 1 chr16 GO:0005911 Not Cancer Driver No 151 0.13 575 82 0.143 0
FLNA FLNA P21333 Filamin-A chrX GO:0005911 Census Yes 416 0.157 1456 214 0.147 28
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0005911 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLRT1 FLRT1 Q9NZU1 Leucine-rich repeat transmembrane protein FLRT1 chr11 GO:0005911 Not Cancer Driver No 74 0.115 90 9 0.1 0
FLRT2_ENST00000554746 FLRT2 O43155 Leucine-rich repeat transmembrane protein FLRT2 chr14 GO:0005911 Not Cancer Driver No 225 0.341 80 21 0.263 0
FLRT3_ENST00000341420 FLRT3 Q9NZU0 Leucine-rich repeat transmembrane protein FLRT3 chr20 GO:0005911 Not Cancer Driver No 108 0.166 112 15 0.134 4
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0005911 Not Cancer Driver No 69 0.136 415 58 0.14 0
FSCN1 FSCN1 Q16658 Fascin chr7 GO:0005911 Not Cancer Driver No 58 0.118 81 5 0.062 0
FXYD1_ENST00000455515 FXYD1 O00168 Phospholemman chr19 GO:0005911 Not Cancer Driver No 10 0.109 22 4 0.182 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0005911 Not Cancer Driver No 57 0.106 33 5 0.152 19
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 GO:0005911 Not Cancer Driver No 79 0.114 570 68 0.119 1
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0005911 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJA4 GJA4 P35212 Gap junction alpha-4 protein chr1 GO:0005911 Not Cancer Driver No 48 0.144 74 14 0.189 0
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0005911 Not Cancer Driver No 74 0.207 92 21 0.228 5
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0005911 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJB3 GJB3 O75712 Gap junction beta-3 protein chr1 GO:0005911 Not Cancer Driver No 48 0.178 13 0 0.0 6
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0005911 Not Cancer Driver No 42 0.161 12 4 0.333 4
GJC1_ENST00000590758 GJC1 P36383 Gap junction gamma-1 protein chr17 GO:0005911 Not Cancer Driver No 63 0.159 150 30 0.2 0
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0005911 Not Cancer Driver No 33 0.075 225 10 0.044 6
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0005911 Not Cancer Driver No 28 0.129 10 1 0.1 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0005911 Not Cancer Driver No 95 0.152 258 43 0.167 2
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0005911 Not Cancer Driver No 7 0.083 4 0 0.0 4
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0005911 Not Cancer Driver No 173 0.125 974 135 0.139 0
HEPACAM HEPACAM Q14CZ8 Hepatocyte cell adhesion molecule chr11 GO:0005911 Not Cancer Driver No 62 0.149 159 14 0.088 11
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0005911 Not Cancer Driver No 60 0.144 12 0 0.0 0
IGSF11 IGSF11 Q5DX21 Immunoglobulin superfamily member 11 chr3 GO:0005911 Not Cancer Driver No 98 0.227 159 28 0.176 0
ILDR1_ENST00000344209 ILDR1 Q86SU0 Immunoglobulin-like domain-containing receptor 1 chr3 GO:0005911 Not Cancer Driver No 112 0.205 260 66 0.254 1
ILDR2 ILDR2 Q71H61 Immunoglobulin-like domain-containing receptor 2 chr1 GO:0005911 Not Cancer Driver No 117 0.183 355 49 0.138 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0005911 Not Cancer Driver No 183 0.11 351 35 0.1 0
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0005911 Not Cancer Driver No 233 0.143 257 36 0.14 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0005911 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0005911 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0005911 Not Cancer Driver No 124 0.157 66 5 0.076 30
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0005911 Census Yes 139 0.224 43 10 0.233 1
JAM2_ENST00000480456 JAM2 P57087 Junctional adhesion molecule B chr21 GO:0005911 Not Cancer Driver No 63 0.211 64 16 0.25 2
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0005911 Not Cancer Driver No 50 0.161 62 11 0.177 2
JUP JUP P14923 Junction plakoglobin chr17 GO:0005911 Not Cancer Driver No 112 0.15 241 37 0.154 0
KAZN KAZN Q674X7 Kazrin chr1 GO:0005911 Not Cancer Driver No 81 0.105 528 56 0.106 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0005911 Not Cancer Driver No 96 0.192 82 16 0.195 5
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0005911 Not Cancer Driver No 213 0.347 218 53 0.243 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 GO:0005911 Not Cancer Driver No 103 0.241 49 11 0.224 12
KIAA1210 KIAA1210 Q9ULL0 Acrosomal protein KIAA1210 chrX GO:0005911 Not Cancer Driver No 360 0.211 1528 314 0.205 0
KIFC3_ENST00000379655 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 GO:0005911 Not Cancer Driver No 84 0.101 487 42 0.086 0
KIRREL1 KIRREL1 Q96J84 Kin of IRRE-like protein 1 chr1 GO:0005911 Not Cancer Driver No 141 0.186 273 57 0.209 1
KIRREL2 KIRREL2 Q6UWL6 Kin of IRRE-like protein 2 chr19 GO:0005911 Not Cancer Driver No 139 0.196 303 68 0.224 0
KIRREL3 KIRREL3 Q8IZU9 Kin of IRRE-like protein 3 chr11 GO:0005911 Not Cancer Driver No 111 0.143 223 32 0.143 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0005911 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLHL24_ENST00000242810 KLHL24 Q6TFL4 Kelch-like protein 24 chr3 GO:0005911 Not Cancer Driver No 102 0.17 17 6 0.353 0
KRIT1_ENST00000394505 KRIT1 O00522 Krev interaction trapped protein 1 chr7 GO:0005911 Not Cancer Driver No 80 0.109 113 17 0.15 2
LAMA1 LAMA1 P25391 Laminin subunit alpha-1 chr18 GO:0005911 Not Cancer Driver No 600 0.195 329 71 0.216 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0005911 Not Cancer Driver No 37 0.141 213 29 0.136 0
LCP2 LCP2 Q13094 Lymphocyte cytosolic protein 2 chr5 GO:0005911 Not Cancer Driver No 107 0.201 390 80 0.205 0
LIMS1_ENST00000393310 LIMS1 P48059 LIM and senescent cell antigen-like-containing domain protein 1 chr2 GO:0005911 Not Cancer Driver No 34 0.105 0 0 0.0 0
LIMS2_ENST00000355119 LIMS2 Q7Z4I7 LIM and senescent cell antigen-like-containing domain protein 2 chr2 GO:0005911 Not Cancer Driver No 55 0.161 8 0 0.0 0
LIN7A LIN7A O14910 Protein lin-7 homolog A chr12 GO:0005911 Not Cancer Driver No 76 0.326 127 29 0.228 0
LIN7B LIN7B Q9HAP6 Protein lin-7 homolog B chr19 GO:0005911 Not Cancer Driver No 26 0.126 107 16 0.15 0
LIN7C LIN7C Q9NUP9 Protein lin-7 homolog C chr11 GO:0005911 Not Cancer Driver No 22 0.112 102 11 0.108 0
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 GO:0005911 Not Cancer Driver No 89 0.137 330 42 0.127 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 GO:0005911 Not Cancer Driver No 260 0.174 1212 220 0.182 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0005911 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAGI3 MAGI3 Q5TCQ9 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 chr1 GO:0005911 Not Cancer Driver No 154 0.104 1039 105 0.101 0
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0005911 Census Yes 58 0.145 105 14 0.133 4
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0005911 Not Cancer Driver No 81 0.149 235 37 0.157 0
MARVELD2_ENST00000325631 MARVELD2 Q8N4S9 MARVEL domain-containing protein 2 chr5 GO:0005911 Not Cancer Driver No 74 0.133 251 36 0.143 0
MICALL2 MICALL2 Q8IY33 MICAL-like protein 2 chr7 GO:0005911 Not Cancer Driver No 110 0.122 675 88 0.13 0
MIP MIP P30301 Lens fiber major intrinsic protein chr12 GO:0005911 Not Cancer Driver No 71 0.27 20 1 0.05 6
MPP1 MPP1 Q00013 55 kDa erythrocyte membrane protein chrX GO:0005911 Not Cancer Driver No 79 0.17 194 33 0.17 0
MPP2_ENST00000461854 MPP2 Q14168 MAGUK p55 subfamily member 2 chr17 GO:0005911 Not Cancer Driver No 109 0.189 112 18 0.161 0
MPP3_ENST00000398389 MPP3 Q13368 MAGUK p55 subfamily member 3 chr17 GO:0005911 Not Cancer Driver No 70 0.12 228 33 0.145 0
MPP4 MPP4 Q96JB8 MAGUK p55 subfamily member 4 chr2 GO:0005911 Not Cancer Driver No 100 0.157 111 16 0.144 0
MPP5 PALS1 Q8N3R9 Protein PALS1 chr14 GO:0005911 Not Cancer Driver No 70 0.104 337 33 0.098 0
MPP6_ENST00000396475 PALS2 Q9NZW5 Protein PALS2 chr7 GO:0005911 Not Cancer Driver No 98 0.181 78 13 0.167 0
MPP7 MPP7 Q5T2T1 MAGUK p55 subfamily member 7 chr10 GO:0005911 Not Cancer Driver No 132 0.229 199 72 0.362 0
MTDH MTDH Q86UE4 Protein LYRIC chr8 GO:0005911 Not Cancer Driver No 83 0.143 516 81 0.157 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0005911 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYH1 MYH1 P12882 Myosin-1 chr17 GO:0005911 Not Cancer Driver No 546 0.282 1153 335 0.291 0
MYH2_ENST00000397183 MYH2 Q9UKX2 Myosin-2 chr17 GO:0005911 Not Cancer Driver No 572 0.295 1073 338 0.315 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0005911 Not Cancer Driver No 48 0.127 111 17 0.153 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0005911 Not Cancer Driver No 63 0.117 296 29 0.098 0
NECTIN3 NECTIN3 Q9NQS3 Nectin-3 chr3 GO:0005911 Not Cancer Driver No 72 0.131 106 9 0.085 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0005911 Not Cancer Driver No 57 0.133 172 25 0.145 0
NPHP1_ENST00000393272 NPHP1 O15259 Nephrocystin-1 chr2 GO:0005911 Not Cancer Driver No 108 0.148 259 32 0.124 1
NPHP4 NPHP4 O75161 Nephrocystin-4 chr1 GO:0005911 Not Cancer Driver No 176 0.123 469 54 0.115 17
NPHS1 NPHS1 O60500 Nephrin chr19 GO:0005911 Not Cancer Driver No 230 0.185 484 108 0.223 62
NPHS2 NPHS2 Q9NP85 Podocin chr1 GO:0005911 Not Cancer Driver No 72 0.188 130 18 0.138 50
NRAP_ENST00000359988 NRAP Q86VF7 Nebulin-related-anchoring protein chr10 GO:0005911 Not Cancer Driver No 302 0.175 706 139 0.197 0
OBSCN_ENST00000422127 OBSCN Q5VST9 Obscurin chr1 GO:0005911 Not Cancer Driver No 1208 0.152 2623 368 0.14 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 GO:0005911 Not Cancer Driver No 233 0.123 553 60 0.108 0
OCLN OCLN Q16625 Occludin chr5 GO:0005911 Not Cancer Driver No 54 0.103 244 21 0.086 1
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0005911 Not Cancer Driver No 51 0.086 14 2 0.143 0
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 GO:0005911 Not Cancer Driver No 51 0.105 301 27 0.09 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0005911 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0005911 Compendium Yes 89 0.17 242 49 0.202 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0005911 Not Cancer Driver No 54 0.127 45 7 0.156 2
PANX2 PANX2 Q96RD6 Pannexin-2 chr22 GO:0005911 Not Cancer Driver No 73 0.108 293 14 0.048 0
PANX3 PANX3 Q96QZ0 Pannexin-3 chr11 GO:0005911 Not Cancer Driver No 92 0.235 10 4 0.4 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 GO:0005911 Not Cancer Driver No 200 0.147 1144 170 0.149 2
PCDH12 PCDH12 Q9NPG4 Protocadherin-12 chr5 GO:0005911 Not Cancer Driver No 158 0.133 582 80 0.137 0
PCDH1_ENST00000394536 PCDH1 Q08174 Protocadherin-1 chr5 GO:0005911 Not Cancer Driver No 140 0.132 676 90 0.133 0
PCDHGA12 PCDHGA12 O60330 Protocadherin gamma-A12 chr5 GO:0005911 Not Cancer Driver No 201 0.216 323 62 0.192 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0005911 Not Cancer Driver No 14 0.047 38 4 0.105 0
PDZD11_ENST00000374454 PDZD11 Q5EBL8 PDZ domain-containing protein 11 chrX GO:0005911 Not Cancer Driver No 20 0.143 46 8 0.174 0
PDZD2 PDZD2 O15018 PDZ domain-containing protein 2 chr5 GO:0005911 Not Cancer Driver No 449 0.158 2296 360 0.157 0
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 GO:0005911 Not Cancer Driver No 2 0.003 153 2 0.013 0
PERP PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0005911 Not Cancer Driver No 28 0.145 0 0 0.0 1
PGM5 PGM5 Q15124 Phosphoglucomutase-like protein 5 chr9 GO:0005911 Not Cancer Driver No 165 0.291 54 4 0.074 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0005911 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0005911 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0005911 Not Cancer Driver No 278 0.133 848 101 0.119 1
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0005911 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKP1 PKP1 Q13835 Plakophilin-1 chr1 GO:0005911 Not Cancer Driver No 106 0.142 190 26 0.137 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 GO:0005911 Not Cancer Driver No 176 0.2 434 98 0.226 8
PKP3 PKP3 Q9Y446 Plakophilin-3 chr11 GO:0005911 Not Cancer Driver No 72 0.09 357 22 0.062 0
PKP4 PKP4 Q99569 Plakophilin-4 chr2 GO:0005911 Not Cancer Driver No 172 0.144 756 119 0.157 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 GO:0005911 Not Cancer Driver No 152 0.136 919 121 0.132 0
PLEKHG5_ENST00000400913 PLEKHG5 O94827 Pleckstrin homology domain-containing family G member 5 chr1 GO:0005911 Not Cancer Driver No 93 0.092 537 54 0.101 3
PNN PNN Q9H307 Pinin chr14 GO:0005911 Not Cancer Driver No 94 0.131 700 90 0.129 0
PODXL PODXL O00592 Podocalyxin chr7 GO:0005911 Not Cancer Driver No 69 0.124 432 56 0.13 0
POF1B_ENST00000262753 POF1B Q8WVV4 Protein POF1B chrX GO:0005911 Not Cancer Driver No 154 0.261 391 104 0.266 1
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0005911 Not Cancer Driver No 36 0.098 94 13 0.138 0
PPL PPL O60437 Periplakin chr16 GO:0005911 Not Cancer Driver No 219 0.125 1133 133 0.117 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0005911 Compendium Yes 85 0.163 140 27 0.193 7
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0005911 Compendium Yes 79 0.117 43 9 0.209 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0005911 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0005911 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0005911 Census Yes 201 0.22 189 33 0.175 2
PTK7_ENST00000230419 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 GO:0005911 Not Cancer Driver No 153 0.143 359 58 0.162 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0005911 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0005911 Not Cancer Driver No 184 0.138 401 61 0.152 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0005911 Census, Compendium Yes 292 0.203 302 57 0.189 0
PTPRM_ENST00000332175 PTPRM P28827 Receptor-type tyrosine-protein phosphatase mu chr18 GO:0005911 Not Cancer Driver No 256 0.176 365 60 0.164 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0005911 Not Cancer Driver No 248 0.172 325 64 0.197 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0005911 Not Cancer Driver No 62 0.105 341 24 0.07 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0005911 Not Cancer Driver No 10 0.054 42 5 0.119 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0005911 Not Cancer Driver No 26 0.141 14 3 0.214 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0005911 Not Cancer Driver No 216 0.144 803 116 0.144 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0005911 Not Cancer Driver No 73 0.076 505 48 0.095 0
RHO RHO P08100 Rhodopsin chr3 GO:0005911 Not Cancer Driver No 68 0.195 18 3 0.167 69
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 GO:0005911 Not Cancer Driver No 177 0.135 586 94 0.16 8
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 GO:0005911 Not Cancer Driver No 42 0.11 243 17 0.07 0
SCN1A_ENST00000423058 SCN1A P35498 Sodium channel protein type 1 subunit alpha chr2 GO:0005911 Not Cancer Driver No 497 0.247 455 121 0.266 396
SCN1B_ENST00000262631 SCN1B Q07699 Sodium channel subunit beta-1 chr19 GO:0005911 Not Cancer Driver No 35 0.161 4 1 0.25 5
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0005911 Not Cancer Driver No 502 0.25 435 133 0.306 65
SCN4B SCN4B Q8IWT1 Sodium channel subunit beta-4 chr11 GO:0005911 Not Cancer Driver No 23 0.101 46 4 0.087 3
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0005911 Not Cancer Driver No 491 0.244 550 144 0.262 190
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0005911 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SDCCAG8 SDCCAG8 Q86SQ7 Serologically defined colon cancer antigen 8 chr1 GO:0005911 Not Cancer Driver No 110 0.154 487 73 0.15 0
SGCA SGCA Q16586 Alpha-sarcoglycan chr17 GO:0005911 Not Cancer Driver No 58 0.15 82 9 0.11 29
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 GO:0005911 Not Cancer Driver No 83 0.111 77 9 0.117 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX GO:0005911 Not Cancer Driver No 102 0.153 530 82 0.155 0
SIPA1L3 SIPA1L3 O60292 Signal-induced proliferation-associated 1-like protein 3 chr19 GO:0005911 Not Cancer Driver No 273 0.153 1257 190 0.151 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0005911 Not Cancer Driver No 56 0.144 85 17 0.2 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 GO:0005911 Not Cancer Driver No 67 0.187 130 27 0.208 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0005911 Not Cancer Driver No 51 0.104 13 2 0.154 48
SLC2A2 SLC2A2 P11168 Solute carrier family 2, facilitated glucose transporter member 2 chr3 GO:0005911 Not Cancer Driver No 102 0.195 15 4 0.267 3
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0005911 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0005911 Not Cancer Driver No 89 0.109 251 29 0.116 1
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0005911 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SPECC1L SPECC1L Q69YQ0 Cytospin-A chr22 GO:0005911 Not Cancer Driver No 113 0.101 928 93 0.1 3
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 GO:0005911 Not Cancer Driver No 317 0.133 877 126 0.144 2
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0005911 Not Cancer Driver No 312 0.122 866 103 0.119 0
STARD10_ENST00000543304 STARD10 Q9Y365 START domain-containing protein 10 chr11 GO:0005911 Not Cancer Driver No 39 0.134 75 6 0.08 0
STEAP1 STEAP1 Q9UHE8 Metalloreductase STEAP1 chr7 GO:0005911 Not Cancer Driver No 45 0.133 26 3 0.115 0
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0005911 Not Cancer Driver No 51 0.176 129 30 0.233 0
SV2A SV2A Q7L0J3 Synaptic vesicle glycoprotein 2A chr1 GO:0005911 Not Cancer Driver No 134 0.181 150 31 0.207 0
TCHP_ENST00000405876 TCHP Q9BT92 Trichoplein keratin filament-binding protein chr12 GO:0005911 Not Cancer Driver No 60 0.12 356 50 0.14 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0005911 Not Cancer Driver No 219 0.195 126 22 0.175 10
THEMIS_ENST00000368250 THEMIS Q8N1K5 Protein THEMIS chr6 GO:0005911 Not Cancer Driver No 208 0.324 111 34 0.306 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0005911 Not Cancer Driver No 370 0.233 810 194 0.24 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0005911 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TMEM47 TMEM47 Q9BQJ4 Transmembrane protein 47 chrX GO:0005911 Not Cancer Driver No 42 0.232 0 0 0.0 0
TMEM65 TMEM65 Q6PI78 Transmembrane protein 65 chr8 GO:0005911 Not Cancer Driver No 23 0.096 50 1 0.02 0
TRPC4_ENST00000379705 TRPC4 Q9UBN4 Short transient receptor potential channel 4 chr13 GO:0005911 Not Cancer Driver No 322 0.33 195 66 0.338 0
TRPC6 TRPC6 Q9Y210 Short transient receptor potential channel 6 chr11 GO:0005911 Not Cancer Driver No 202 0.217 165 46 0.279 10
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0005911 Not Cancer Driver No 50 0.143 52 3 0.058 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX GO:0005911 Not Cancer Driver No 117 0.111 165 22 0.133 6
USP53 USP53 Q70EK8 Inactive ubiquitin carboxyl-terminal hydrolase 53 chr4 GO:0005911 Not Cancer Driver No 119 0.111 582 64 0.11 0
VAMP5 VAMP5 O95183 Vesicle-associated membrane protein 5 chr2 GO:0005911 Not Cancer Driver No 17 0.147 19 1 0.053 0
VANGL2 VANGL2 Q9ULK5 Vang-like protein 2 chr1 GO:0005911 Not Cancer Driver No 122 0.234 150 37 0.247 3
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0005911 Census, Compendium Yes 165 0.195 113 19 0.168 0
VCL VCL P18206 Vinculin chr10 GO:0005911 Not Cancer Driver No 114 0.101 673 80 0.119 2
VSIG10 VSIG10 Q8N0Z9 V-set and immunoglobulin domain-containing protein 10 chr12 GO:0005911 Not Cancer Driver No 71 0.131 92 9 0.098 0
VSIG10L2 VSIG10L2 P0DP72 V-set and immunoglobulin domain-containing protein 10-like 2 chr11 GO:0005911 Not Cancer Driver No 2 0.003 238 2 0.008 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0005911 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 GO:0005911 Not Cancer Driver No 61 0.122 400 43 0.107 0
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0005911 Not Cancer Driver No 66 0.109 30 7 0.233 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 GO:0005911 Not Cancer Driver No 15 0.061 55 3 0.055 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0005911 Not Cancer Driver No 126 0.204 117 17 0.145 8