Total number of protein in "GO:0005546" GO term: 81
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTN2_ENST00000366578 | ACTN2 | P35609 | Alpha-actinin-2 | chr1 | GO:0005546 | Not Cancer Driver | No | 227 | 0.254 | 131 | 29 | 0.221 | 9 |
| ADAP2 | ADAP2 | Q9NPF8 | Arf-GAP with dual PH domain-containing protein 2 | chr17 | GO:0005546 | Not Cancer Driver | No | 42 | 0.11 | 30 | 5 | 0.167 | 0 |
| ALOX15_ENST00000293761 | ALOX15 | P16050 | Polyunsaturated fatty acid lipoxygenase ALOX15 | chr17 | GO:0005546 | Not Cancer Driver | No | 84 | 0.127 | 46 | 7 | 0.152 | 0 |
| AMER1 | AMER1 | Q5JTC6 | APC membrane recruitment protein 1 | chrX | GO:0005546 | Census, Compendium | Yes | 234 | 0.206 | 1039 | 219 | 0.211 | 0 |
| AMER2 | AMER2 | Q8N7J2 | APC membrane recruitment protein 2 | chr13 | GO:0005546 | Not Cancer Driver | No | 118 | 0.176 | 663 | 116 | 0.175 | 0 |
| AMER3_ENST00000321420 | AMER3 | Q8N944 | APC membrane recruitment protein 3 | chr2 | GO:0005546 | Not Cancer Driver | No | 244 | 0.283 | 736 | 211 | 0.287 | 0 |
| ANXA2_ENST00000396024 | ANXA2 | P07355 | Annexin A2 | chr15 | GO:0005546 | Not Cancer Driver | No | 49 | 0.145 | 20 | 4 | 0.2 | 0 |
| ANXA9 | ANXA9 | O76027 | Annexin A9 | chr1 | GO:0005546 | Not Cancer Driver | No | 52 | 0.151 | 42 | 7 | 0.167 | 0 |
| ASAP1 | ASAP1 | Q9ULH1 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 | chr8 | GO:0005546 | Not Cancer Driver | No | 183 | 0.162 | 584 | 108 | 0.185 | 0 |
| AVIL | AVIL | O75366 | Advillin | chr12 | GO:0005546 | Not Cancer Driver | No | 91 | 0.111 | 138 | 17 | 0.123 | 2 |
| CAPG_ENST00000409724 | CAPG | P40121 | Macrophage-capping protein | chr2 | GO:0005546 | Not Cancer Driver | No | 45 | 0.129 | 95 | 7 | 0.074 | 0 |
| CGAS | CGAS | Q8N884 | Cyclic GMP-AMP synthase | chr6 | GO:0005546 | Not Cancer Driver | No | 50 | 0.096 | 173 | 7 | 0.04 | 0 |
| COMMD1 | COMMD1 | Q8N668 | COMM domain-containing protein 1 | chr2 | GO:0005546 | Not Cancer Driver | No | 21 | 0.111 | 17 | 0 | 0.0 | 0 |
| EXOC1 | EXOC1 | Q9NV70 | Exocyst complex component 1 | chr4 | GO:0005546 | Not Cancer Driver | No | 128 | 0.143 | 154 | 22 | 0.143 | 0 |
| EXOC1L | EXOC1L | A0A1B0GW35 | Exocyst complex component 1-like | chr4 | GO:0005546 | Not Cancer Driver | No | 3 | 0.017 | 0 | 0 | 0.0 | 0 |
| FCHO2 | FCHO2 | Q0JRZ9 | F-BAR domain only protein 2 | chr5 | GO:0005546 | Not Cancer Driver | No | 79 | 0.098 | 373 | 45 | 0.121 | 0 |
| FLII | FLII | Q13045 | Protein flightless-1 homolog | chr17 | GO:0005546 | Not Cancer Driver | No | 128 | 0.101 | 206 | 32 | 0.155 | 0 |
| FRMPD4 | FRMPD4 | Q14CM0 | FERM and PDZ domain-containing protein 4 | chrX | GO:0005546 | Not Cancer Driver | No | 282 | 0.213 | 793 | 184 | 0.232 | 1 |
| FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:0005546 | Not Cancer Driver | No | 90 | 0.157 | 22 | 2 | 0.091 | 0 |
| GRAMD2A | GRAMD2A | Q8IUY3 | GRAM domain-containing protein 2A | chr15 | GO:0005546 | Not Cancer Driver | No | 49 | 0.138 | 106 | 8 | 0.075 | 0 |
| GSDMA | GSDMA | Q96QA5 | Gasdermin-A | chr17 | GO:0005546 | Not Cancer Driver | No | 67 | 0.151 | 87 | 15 | 0.172 | 0 |
| GSDMB | GSDMB | Q8TAX9 | Gasdermin-B | chr17 | GO:0005546 | Not Cancer Driver | No | 50 | 0.12 | 84 | 11 | 0.131 | 0 |
| GSDMC | GSDMC | Q9BYG8 | Gasdermin-C | chr8 | GO:0005546 | Not Cancer Driver | No | 125 | 0.246 | 0 | 0 | 0.0 | 0 |
| GSDMD_ENST00000262580 | GSDMD | P57764 | Gasdermin-D | chr8 | GO:0005546 | Not Cancer Driver | No | 47 | 0.097 | 156 | 16 | 0.103 | 0 |
| GSDME_ENST00000409775 | GSDME | O60443 | Gasdermin-E | chr7 | GO:0005546 | Not Cancer Driver | No | 81 | 0.163 | 14 | 3 | 0.214 | 0 |
| GSN | GSN | P06396 | Gelsolin | chr9 | GO:0005546 | Not Cancer Driver | No | 76 | 0.097 | 316 | 28 | 0.089 | 2 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0005546 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0005546 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| JPH2 | JPH2 | Q9BR39 | Junctophilin-2 | chr20 | GO:0005546 | Not Cancer Driver | No | 137 | 0.197 | 542 | 97 | 0.179 | 4 |
| KCNJ1 | KCNJ1 | P48048 | ATP-sensitive inward rectifier potassium channel 1 | chr11 | GO:0005546 | Not Cancer Driver | No | 83 | 0.212 | 10 | 0 | 0.0 | 13 |
| KCNJ2_ENST00000535240 | KCNJ2 | P63252 | Inward rectifier potassium channel 2 | chr17 | GO:0005546 | Not Cancer Driver | No | 103 | 0.241 | 49 | 11 | 0.224 | 12 |
| KCNQ1 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0005546 | Not Cancer Driver | No | 78 | 0.115 | 219 | 20 | 0.091 | 132 |
| KRIT1_ENST00000394505 | KRIT1 | O00522 | Krev interaction trapped protein 1 | chr7 | GO:0005546 | Not Cancer Driver | No | 80 | 0.109 | 113 | 17 | 0.15 | 2 |
| LDLRAP1 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0005546 | Not Cancer Driver | No | 36 | 0.117 | 119 | 17 | 0.143 | 1 |
| MAPKAP1 | MAPKAP1 | Q9BPZ7 | Target of rapamycin complex 2 subunit MAPKAP1 | chr9 | GO:0005546 | Not Cancer Driver | No | 70 | 0.134 | 173 | 25 | 0.145 | 0 |
| MARK1_ENST00000366917 | MARK1 | Q9P0L2 | Serine/threonine-protein kinase MARK1 | chr1 | GO:0005546 | Not Cancer Driver | No | 161 | 0.203 | 454 | 108 | 0.238 | 0 |
| MTSS1L | MTSS2 | Q765P7 | Protein MTSS 2 | chr16 | GO:0005546 | Not Cancer Driver | No | 62 | 0.083 | 582 | 49 | 0.084 | 0 |
| MYO1B | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | GO:0005546 | Not Cancer Driver | No | 144 | 0.127 | 34 | 4 | 0.118 | 0 |
| MYO1G | MYO1G | B0I1T2 | Unconventional myosin-Ig | chr7 | GO:0005546 | Not Cancer Driver | No | 125 | 0.123 | 117 | 12 | 0.103 | 0 |
| OBSCN_ENST00000422127 | OBSCN | Q5VST9 | Obscurin | chr1 | GO:0005546 | Not Cancer Driver | No | 1208 | 0.152 | 2623 | 368 | 0.14 | 0 |
| OSBPL2_ENST00000643981 | OSBPL2 | Q9H1P3 | Oxysterol-binding protein-related protein 2 | chr20 | GO:0005546 | Not Cancer Driver | No | 57 | 0.119 | 173 | 18 | 0.104 | 0 |
| PARD3 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | GO:0005546 | Not Cancer Driver | No | 200 | 0.147 | 1144 | 170 | 0.149 | 2 |
| PFN1 | PFN1 | P07737 | Profilin-1 | chr17 | GO:0005546 | Not Cancer Driver | No | 16 | 0.114 | 7 | 1 | 0.143 | 3 |
| PFN2 | PFN2 | P35080 | Profilin-2 | chr3 | GO:0005546 | Not Cancer Driver | No | 20 | 0.143 | 0 | 0 | 0.0 | 0 |
| PHLDA3 | PHLDA3 | Q9Y5J5 | Pleckstrin homology-like domain family A member 3 | chr1 | GO:0005546 | Not Cancer Driver | No | 20 | 0.157 | 0 | 0 | 0.0 | 0 |
| PICALM | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0005546 | Census | Yes | 89 | 0.137 | 320 | 42 | 0.131 | 0 |
| PLA2G4E | PLA2G4E | Q3MJ16 | Cytosolic phospholipase A2 epsilon | chr15 | GO:0005546 | Not Cancer Driver | No | 71 | 0.082 | 123 | 6 | 0.049 | 0 |
| PLCB1 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0005546 | Not Cancer Driver | No | 313 | 0.257 | 481 | 104 | 0.216 | 0 |
| PLCD1_ENST00000334661 | PLCD1 | P51178 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | chr3 | GO:0005546 | Not Cancer Driver | No | 94 | 0.124 | 111 | 13 | 0.117 | 2 |
| PLCZ1 | PLCZ1 | Q86YW0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 | chr12 | GO:0005546 | Not Cancer Driver | No | 151 | 0.248 | 37 | 20 | 0.541 | 1 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | GO:0005546 | Not Cancer Driver | No | 136 | 0.175 | 687 | 128 | 0.186 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | GO:0005546 | Not Cancer Driver | No | 25 | 0.124 | 25 | 2 | 0.08 | 0 |
| RAG2 | RAG2 | P55895 | V(D)J recombination-activating protein 2 | chr11 | GO:0005546 | Not Cancer Driver | No | 118 | 0.224 | 85 | 23 | 0.271 | 6 |
| RPH3A | RPH3A | Q9Y2J0 | Rabphilin-3A | chr12 | GO:0005546 | Not Cancer Driver | No | 155 | 0.223 | 427 | 105 | 0.246 | 0 |
| SCIN | SCIN | Q9Y6U3 | Scinderin | chr7 | GO:0005546 | Not Cancer Driver | No | 100 | 0.14 | 170 | 35 | 0.206 | 0 |
| SDCBP2_ENST00000360779 | SDCBP2 | Q9H190 | Syntenin-2 | chr20 | GO:0005546 | Not Cancer Driver | No | 49 | 0.168 | 69 | 9 | 0.13 | 0 |
| SDCBP_ENST00000260130 | SDCBP | O00560 | Syntenin-1 | chr8 | GO:0005546 | Not Cancer Driver | No | 39 | 0.131 | 17 | 2 | 0.118 | 0 |
| SESTD1 | SESTD1 | Q86VW0 | SEC14 domain and spectrin repeat-containing protein 1 | chr2 | GO:0005546 | Not Cancer Driver | No | 100 | 0.144 | 126 | 18 | 0.143 | 0 |
| SH3PXD2A_ENST00000369774 | SH3PXD2A | Q5TCZ1 | SH3 and PX domain-containing protein 2A | chr10 | GO:0005546 | Not Cancer Driver | No | 141 | 0.124 | 797 | 101 | 0.127 | 0 |
| SLC9A1 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0005546 | Not Cancer Driver | No | 89 | 0.109 | 251 | 29 | 0.116 | 1 |
| SNAP91_ENST00000369694 | SNAP91 | O60641 | Clathrin coat assembly protein AP180 | chr6 | GO:0005546 | Not Cancer Driver | No | 203 | 0.224 | 636 | 118 | 0.186 | 0 |
| SNX18 | SNX18 | Q96RF0 | Sorting nexin-18 | chr5 | GO:0005546 | Not Cancer Driver | No | 54 | 0.086 | 236 | 7 | 0.03 | 0 |
| SNX20 | SNX20 | Q7Z614 | Sorting nexin-20 | chr16 | GO:0005546 | Not Cancer Driver | No | 56 | 0.177 | 72 | 12 | 0.167 | 0 |
| SNX21 | SNX21 | Q969T3 | Sorting nexin-21 | chr20 | GO:0005546 | Not Cancer Driver | No | 29 | 0.078 | 174 | 14 | 0.08 | 0 |
| STXBP6_ENST00000419632 | STXBP6 | Q8NFX7 | Syntaxin-binding protein 6 | chr14 | GO:0005546 | Not Cancer Driver | No | 33 | 0.157 | 51 | 6 | 0.118 | 0 |
| SVIL | SVIL | O95425 | Supervillin | chr10 | GO:0005546 | Not Cancer Driver | No | 308 | 0.139 | 1423 | 192 | 0.135 | 0 |
| SYT10 | SYT10 | Q6XYQ8 | Synaptotagmin-10 | chr12 | GO:0005546 | Not Cancer Driver | No | 155 | 0.296 | 163 | 56 | 0.344 | 0 |
| SYT1_ENST00000393240 | SYT1 | P21579 | Synaptotagmin-1 | chr12 | GO:0005546 | Not Cancer Driver | No | 104 | 0.246 | 103 | 36 | 0.35 | 5 |
| SYT5 | SYT5 | O00445 | Synaptotagmin-5 | chr19 | GO:0005546 | Not Cancer Driver | No | 60 | 0.155 | 110 | 11 | 0.1 | 0 |
| SYT7_ENST00000263846 | SYT7 | O43581 | Synaptotagmin-7 | chr11 | GO:0005546 | Not Cancer Driver | No | 63 | 0.156 | 132 | 25 | 0.189 | 0 |
| SYT9 | SYT9 | Q86SS6 | Synaptotagmin-9 | chr11 | GO:0005546 | Not Cancer Driver | No | 120 | 0.244 | 148 | 42 | 0.284 | 0 |
| SYTL2_ENST00000528231 | SYTL2 | Q9HCH5 | Synaptotagmin-like protein 2 | chr11 | GO:0005546 | Not Cancer Driver | No | 137 | 0.147 | 635 | 104 | 0.164 | 0 |
| TIRAP_ENST00000392680 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0005546 | Not Cancer Driver | No | 28 | 0.127 | 80 | 6 | 0.075 | 0 |
| TTPA | TTPA | P49638 | Alpha-tocopherol transfer protein | chr8 | GO:0005546 | Not Cancer Driver | No | 53 | 0.191 | 20 | 1 | 0.05 | 7 |
| TULP1 | TULP1 | O00294 | Tubby-related protein 1 | chr6 | GO:0005546 | Not Cancer Driver | No | 101 | 0.186 | 377 | 76 | 0.202 | 12 |
| TULP3_ENST00000448120 | TULP3 | O75386 | Tubby-related protein 3 | chr12 | GO:0005546 | Not Cancer Driver | No | 66 | 0.149 | 218 | 29 | 0.133 | 0 |
| TWF1_ENST00000395510 | TWF1 | Q12792 | Twinfilin-1 | chr12 | GO:0005546 | Not Cancer Driver | No | 50 | 0.143 | 52 | 3 | 0.058 | 0 |
| TWF2 | TWF2 | Q6IBS0 | Twinfilin-2 | chr3 | GO:0005546 | Not Cancer Driver | No | 34 | 0.097 | 59 | 8 | 0.136 | 0 |
| VIL1 | VIL1 | P09327 | Villin-1 | chr2 | GO:0005546 | Not Cancer Driver | No | 124 | 0.15 | 222 | 38 | 0.171 | 0 |
| VILL_ENST00000383759 | VILL | O15195 | Villin-like protein | chr3 | GO:0005546 | Not Cancer Driver | No | 100 | 0.117 | 222 | 28 | 0.126 | 0 |
| WASHC2C_ENST00000374362 | WASHC2C | Q9Y4E1 | WASH complex subunit 2C | chr10 | GO:0005546 | Not Cancer Driver | No | 90 | 0.068 | 1204 | 89 | 0.074 | 0 |