Total number of protein in "GO:0005539" GO term: 78
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAN | ACAN | P16112 | Aggrecan core protein | chr15 | GO:0005539 | Not Cancer Driver | No | 477 | 0.189 | 1868 | 323 | 0.173 | 2 |
| ADGRE2 | ADGRE2 | Q9UHX3 | Adhesion G protein-coupled receptor E2 | chr19 | GO:0005539 | Not Cancer Driver | No | 134 | 0.163 | 104 | 22 | 0.212 | 1 |
| AGRN | AGRN | O00468 | Agrin | chr1 | GO:0005539 | Not Cancer Driver | No | 188 | 0.091 | 490 | 40 | 0.082 | 5 |
| ANXA6 | ANXA6 | P08133 | Annexin A6 | chr5 | GO:0005539 | Not Cancer Driver | No | 95 | 0.141 | 107 | 15 | 0.14 | 0 |
| BCAN | BCAN | Q96GW7 | Brevican core protein | chr1 | GO:0005539 | Not Cancer Driver | No | 198 | 0.217 | 341 | 75 | 0.22 | 0 |
| BGN | BGN | P21810 | Biglycan | chrX | GO:0005539 | Not Cancer Driver | No | 63 | 0.171 | 26 | 3 | 0.115 | 2 |
| C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | GO:0005539 | Not Cancer Driver | No | 14 | 0.05 | 103 | 6 | 0.058 | 2 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | GO:0005539 | Not Cancer Driver | No | 75 | 0.101 | 542 | 60 | 0.111 | 0 |
| CEMIP_ENST00000356249 | CEMIP | Q8WUJ3 | Cell migration-inducing and hyaluronan-binding protein | chr15 | GO:0005539 | Not Cancer Driver | No | 207 | 0.152 | 105 | 10 | 0.095 | 0 |
| CHODL | CHODL | Q9H9P2 | Chondrolectin | chr21 | GO:0005539 | Not Cancer Driver | No | 50 | 0.183 | 45 | 7 | 0.156 | 0 |
| COL11A1 | COL11A1 | P12107 | Collagen alpha-1(XI) chain | chr1 | GO:0005539 | Not Cancer Driver | No | 749 | 0.415 | 1436 | 617 | 0.43 | 8 |
| CRISPLD2 | CRISPLD2 | Q9H0B8 | Cysteine-rich secretory protein LCCL domain-containing 2 | chr16 | GO:0005539 | Not Cancer Driver | No | 68 | 0.137 | 79 | 10 | 0.127 | 0 |
| DCN | DCN | P07585 | Decorin | chr12 | GO:0005539 | Not Cancer Driver | No | 96 | 0.267 | 81 | 26 | 0.321 | 0 |
| DPYSL3_ENST00000398514 | DPYSL3 | Q14195 | Dihydropyrimidinase-related protein 3 | chr5 | GO:0005539 | Not Cancer Driver | No | 93 | 0.163 | 128 | 14 | 0.109 | 0 |
| EGFLAM | EGFLAM | Q63HQ2 | Pikachurin | chr5 | GO:0005539 | Not Cancer Driver | No | 283 | 0.278 | 193 | 83 | 0.43 | 0 |
| ENG | ENG | P17813 | Endoglin | chr9 | GO:0005539 | Not Cancer Driver | No | 60 | 0.091 | 114 | 15 | 0.132 | 32 |
| EPYC | EPYC | Q99645 | Epiphycan | chr12 | GO:0005539 | Not Cancer Driver | No | 61 | 0.189 | 80 | 20 | 0.25 | 0 |
| EXTL2 | EXTL2 | Q9UBQ6 | Exostosin-like 2 | chr1 | GO:0005539 | Not Cancer Driver | No | 50 | 0.152 | 0 | 0 | 0.0 | 0 |
| GNS | GNS | P15586 | N-acetylglucosamine-6-sulfatase | chr12 | GO:0005539 | Not Cancer Driver | No | 48 | 0.087 | 22 | 0 | 0.0 | 3 |
| HABP2 | HABP2 | Q14520 | Hyaluronan-binding protein 2 | chr10 | GO:0005539 | Not Cancer Driver | No | 97 | 0.173 | 55 | 8 | 0.145 | 1 |
| HAPLN1 | HAPLN1 | P10915 | Hyaluronan and proteoglycan link protein 1 | chr5 | GO:0005539 | Not Cancer Driver | No | 107 | 0.302 | 8 | 2 | 0.25 | 0 |
| HAPLN2 | HAPLN2 | Q9GZV7 | Hyaluronan and proteoglycan link protein 2 | chr1 | GO:0005539 | Not Cancer Driver | No | 27 | 0.079 | 35 | 1 | 0.029 | 0 |
| HAPLN3_ENST00000359595 | HAPLN3 | Q96S86 | Hyaluronan and proteoglycan link protein 3 | chr15 | GO:0005539 | Not Cancer Driver | No | 61 | 0.169 | 31 | 5 | 0.161 | 0 |
| HAPLN4 | HAPLN4 | Q86UW8 | Hyaluronan and proteoglycan link protein 4 | chr19 | GO:0005539 | Not Cancer Driver | No | 60 | 0.149 | 54 | 16 | 0.296 | 0 |
| HK1_ENST00000359426 | HK1 | P19367 | Hexokinase-1 | chr10 | GO:0005539 | Not Cancer Driver | No | 127 | 0.138 | 75 | 16 | 0.213 | 6 |
| HMMR_ENST00000358715 | HMMR | O75330 | Hyaluronan mediated motility receptor | chr5 | GO:0005539 | Not Cancer Driver | No | 81 | 0.112 | 454 | 47 | 0.104 | 0 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0005539 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| IMPG1 | IMPG1 | Q17R60 | Interphotoreceptor matrix proteoglycan 1 | chr6 | GO:0005539 | Not Cancer Driver | No | 238 | 0.299 | 359 | 92 | 0.256 | 1 |
| IMPG2 | IMPG2 | Q9BZV3 | Interphotoreceptor matrix proteoglycan 2 | chr3 | GO:0005539 | Not Cancer Driver | No | 202 | 0.163 | 451 | 64 | 0.142 | 2 |
| ITIH1 | ITIH1 | P19827 | Inter-alpha-trypsin inhibitor heavy chain H1 | chr3 | GO:0005539 | Not Cancer Driver | No | 166 | 0.182 | 180 | 48 | 0.267 | 0 |
| ITIH2 | ITIH2 | P19823 | Inter-alpha-trypsin inhibitor heavy chain H2 | chr10 | GO:0005539 | Not Cancer Driver | No | 204 | 0.216 | 110 | 24 | 0.218 | 0 |
| JCHAIN | JCHAIN | P01591 | Immunoglobulin J chain | chr4 | GO:0005539 | Not Cancer Driver | No | 37 | 0.233 | 9 | 3 | 0.333 | 0 |
| LAYN | LAYN | Q6UX15 | Layilin | chr11 | GO:0005539 | Not Cancer Driver | No | 59 | 0.154 | 116 | 21 | 0.181 | 0 |
| LTBP4 | LTBP4 | Q8N2S1 | Latent-transforming growth factor beta-binding protein 4 | chr19 | GO:0005539 | Not Cancer Driver | No | 191 | 0.118 | 432 | 42 | 0.097 | 1 |
| LYVE1 | LYVE1 | Q9Y5Y7 | Lymphatic vessel endothelial hyaluronic acid receptor 1 | chr11 | GO:0005539 | Not Cancer Driver | No | 34 | 0.106 | 77 | 13 | 0.169 | 0 |
| MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0005539 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
| NCAN | NCAN | O14594 | Neurocan core protein | chr19 | GO:0005539 | Not Cancer Driver | No | 267 | 0.202 | 790 | 158 | 0.2 | 0 |
| NDNF | NDNF | Q8TB73 | Protein NDNF | chr4 | GO:0005539 | Not Cancer Driver | No | 125 | 0.22 | 129 | 29 | 0.225 | 1 |
| NLRP3_ENST00000391828 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:0005539 | Not Cancer Driver | No | 339 | 0.327 | 64 | 33 | 0.516 | 37 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0005539 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0005539 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| PGLYRP1 | PGLYRP1 | O75594 | Peptidoglycan recognition protein 1 | chr19 | GO:0005539 | Not Cancer Driver | No | 34 | 0.173 | 4 | 0 | 0.0 | 0 |
| PGLYRP2 | PGLYRP2 | Q96PD5 | N-acetylmuramoyl-L-alanine amidase | chr19 | GO:0005539 | Not Cancer Driver | No | 111 | 0.193 | 160 | 28 | 0.175 | 0 |
| PGLYRP3 | PGLYRP3 | Q96LB9 | Peptidoglycan recognition protein 3 | chr1 | GO:0005539 | Not Cancer Driver | No | 81 | 0.238 | 0 | 0 | 0.0 | 0 |
| PGLYRP4 | PGLYRP4 | Q96LB8 | Peptidoglycan recognition protein 4 | chr1 | GO:0005539 | Not Cancer Driver | No | 81 | 0.217 | 4 | 1 | 0.25 | 0 |
| PODXL2 | PODXL2 | Q9NZ53 | Podocalyxin-like protein 2 | chr3 | GO:0005539 | Not Cancer Driver | No | 63 | 0.104 | 417 | 48 | 0.115 | 0 |
| PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:0005539 | Not Cancer Driver | No | 11 | 0.067 | 24 | 3 | 0.125 | 0 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | GO:0005539 | Not Cancer Driver | No | 36 | 0.142 | 115 | 7 | 0.061 | 18 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0005539 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
| PTPRF | PTPRF | P10586 | Receptor-type tyrosine-protein phosphatase F | chr1 | GO:0005539 | Not Cancer Driver | No | 268 | 0.141 | 696 | 96 | 0.138 | 0 |
| PTPRS | PTPRS | Q13332 | Receptor-type tyrosine-protein phosphatase S | chr19 | GO:0005539 | Not Cancer Driver | No | 250 | 0.128 | 829 | 111 | 0.134 | 0 |
| REG1A | REG1A | P05451 | Lithostathine-1-alpha | chr2 | GO:0005539 | Not Cancer Driver | No | 97 | 0.584 | 9 | 5 | 0.556 | 0 |
| REG1B | REG1B | P48304 | Lithostathine-1-beta | chr2 | GO:0005539 | Not Cancer Driver | No | 91 | 0.548 | 14 | 8 | 0.571 | 0 |
| REG3A_ENST00000305165 | REG3A | Q06141 | Regenerating islet-derived protein 3-alpha | chr2 | GO:0005539 | Not Cancer Driver | No | 93 | 0.531 | 19 | 10 | 0.526 | 0 |
| REG3G | REG3G | Q6UW15 | Regenerating islet-derived protein 3-gamma | chr2 | GO:0005539 | Not Cancer Driver | No | 81 | 0.463 | 17 | 4 | 0.235 | 0 |
| RNASE7 | RNASE7 | Q9H1E1 | Ribonuclease 7 | chr14 | GO:0005539 | Not Cancer Driver | No | 27 | 0.173 | 42 | 4 | 0.095 | 0 |
| RTN4R | RTN4R | Q9BZR6 | Reticulon-4 receptor | chr22 | GO:0005539 | Not Cancer Driver | No | 38 | 0.08 | 148 | 17 | 0.115 | 5 |
| RTN4RL1 | RTN4RL1 | Q86UN2 | Reticulon-4 receptor-like 1 | chr17 | GO:0005539 | Not Cancer Driver | No | 56 | 0.127 | 142 | 12 | 0.085 | 0 |
| SEMA5A | SEMA5A | Q13591 | Semaphorin-5A | chr5 | GO:0005539 | Not Cancer Driver | No | 266 | 0.248 | 23 | 4 | 0.174 | 0 |
| SERPINA5_ENST00000554276 | SERPINA5 | P05154 | Plasma serine protease inhibitor | chr14 | GO:0005539 | Not Cancer Driver | No | 103 | 0.254 | 24 | 17 | 0.708 | 0 |
| SERPINE2_ENST00000258405 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0005539 | Not Cancer Driver | No | 62 | 0.156 | 0 | 0 | 0.0 | 0 |
| SGSH | SGSH | P51688 | N-sulphoglucosamine sulphohydrolase | chr17 | GO:0005539 | Not Cancer Driver | No | 45 | 0.09 | 44 | 2 | 0.045 | 56 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0005539 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SPOCK2_ENST00000317376 | SPOCK2 | Q92563 | Testican-2 | chr10 | GO:0005539 | Not Cancer Driver | No | 48 | 0.113 | 113 | 8 | 0.071 | 0 |
| SPOCK3_ENST00000511531 | SPOCK3 | Q9BQ16 | Testican-3 | chr4 | GO:0005539 | Not Cancer Driver | No | 132 | 0.303 | 68 | 38 | 0.559 | 0 |
| STAB1 | STAB1 | Q9NY15 | Stabilin-1 | chr3 | GO:0005539 | Not Cancer Driver | No | 341 | 0.133 | 91 | 13 | 0.143 | 0 |
| STAB2 | STAB2 | Q8WWQ8 | Stabilin-2 | chr12 | GO:0005539 | Not Cancer Driver | No | 482 | 0.189 | 101 | 16 | 0.158 | 0 |
| SULF1_ENST00000458141 | SULF1 | Q8IWU6 | Extracellular sulfatase Sulf-1 | chr8 | GO:0005539 | Not Cancer Driver | No | 246 | 0.282 | 269 | 71 | 0.264 | 0 |
| SULF2_ENST00000484875 | SULF2 | Q8IWU5 | Extracellular sulfatase Sulf-2 | chr20 | GO:0005539 | Not Cancer Driver | No | 145 | 0.167 | 142 | 18 | 0.127 | 0 |
| SUSD5 | SUSD5 | O60279 | Sushi domain-containing protein 5 | chr3 | GO:0005539 | Not Cancer Driver | No | 82 | 0.13 | 358 | 57 | 0.159 | 0 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0005539 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| TGFBR3_ENST00000525962 | TGFBR3 | Q03167 | Transforming growth factor beta receptor type 3 | chr1 | GO:0005539 | Not Cancer Driver | No | 129 | 0.152 | 268 | 41 | 0.153 | 0 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0005539 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TNFAIP6 | TNFAIP6 | P98066 | Tumor necrosis factor-inducible gene 6 protein | chr2 | GO:0005539 | Not Cancer Driver | No | 62 | 0.224 | 13 | 5 | 0.385 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0005539 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| VCAN | VCAN | P13611 | Versican core protein | chr5 | GO:0005539 | Not Cancer Driver | No | 647 | 0.191 | 2643 | 483 | 0.183 | 0 |
| VIT_ENST00000389975 | VIT | Q6UXI7 | Vitrin | chr2 | GO:0005539 | Not Cancer Driver | No | 157 | 0.232 | 178 | 31 | 0.174 | 0 |
| ZG16 | ZG16 | O60844 | Zymogen granule membrane protein 16 | chr16 | GO:0005539 | Not Cancer Driver | No | 5 | 0.03 | 7 | 1 | 0.143 | 0 |