Total number of protein in "GO:0005262" GO term: 95
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ANXA2_ENST00000396024 | ANXA2 | P07355 | Annexin A2 | chr15 | GO:0005262 | Not Cancer Driver | No | 49 | 0.145 | 20 | 4 | 0.2 | 0 |
| ANXA6 | ANXA6 | P08133 | Annexin A6 | chr5 | GO:0005262 | Not Cancer Driver | No | 95 | 0.141 | 107 | 15 | 0.14 | 0 |
| ANXA9 | ANXA9 | O76027 | Annexin A9 | chr1 | GO:0005262 | Not Cancer Driver | No | 52 | 0.151 | 42 | 7 | 0.167 | 0 |
| CACNA1A_ENST00000360228 | CACNA1A | O00555 | Voltage-dependent P/Q-type calcium channel subunit alpha-1A | chr19 | GO:0005262 | Not Cancer Driver | No | 436 | 0.174 | 1144 | 132 | 0.115 | 46 |
| CACNA1B | CACNA1B | Q00975 | Voltage-dependent N-type calcium channel subunit alpha-1B | chr9 | GO:0005262 | Not Cancer Driver | No | 416 | 0.178 | 917 | 115 | 0.125 | 0 |
| CACNA1C | CACNA1C | Q13936 | Voltage-dependent L-type calcium channel subunit alpha-1C | chr12 | GO:0005262 | Not Cancer Driver | No | 455 | 0.205 | 744 | 146 | 0.196 | 14 |
| CACNA1D_ENST00000350061 | CACNA1D | Q01668 | Voltage-dependent L-type calcium channel subunit alpha-1D | chr3 | GO:0005262 | Census, Compendium | Yes | 342 | 0.158 | 736 | 126 | 0.171 | 2 |
| CACNA1E_ENST00000621551 | CACNA1E | Q15878 | Voltage-dependent R-type calcium channel subunit alpha-1E | chr1 | GO:0005262 | Not Cancer Driver | No | 778 | 0.336 | 917 | 339 | 0.37 | 14 |
| CACNA1F | CACNA1F | O60840 | Voltage-dependent L-type calcium channel subunit alpha-1F | chrX | GO:0005262 | Not Cancer Driver | No | 284 | 0.144 | 530 | 78 | 0.147 | 20 |
| CACNA1G | CACNA1G | O43497 | Voltage-dependent T-type calcium channel subunit alpha-1G | chr17 | GO:0005262 | Not Cancer Driver | No | 367 | 0.154 | 1022 | 149 | 0.146 | 3 |
| CACNA1H | CACNA1H | O95180 | Voltage-dependent T-type calcium channel subunit alpha-1H | chr16 | GO:0005262 | Not Cancer Driver | No | 323 | 0.137 | 1045 | 141 | 0.135 | 18 |
| CACNA1I | CACNA1I | Q9P0X4 | Voltage-dependent T-type calcium channel subunit alpha-1I | chr22 | GO:0005262 | Not Cancer Driver | No | 272 | 0.122 | 870 | 73 | 0.084 | 0 |
| CACNA1S | CACNA1S | Q13698 | Voltage-dependent L-type calcium channel subunit alpha-1S | chr1 | GO:0005262 | Not Cancer Driver | No | 389 | 0.208 | 382 | 76 | 0.199 | 6 |
| CACNA2D1_ENST00000356253 | CACNA2D1 | P54289 | Voltage-dependent calcium channel subunit alpha-2/delta-1 | chr7 | GO:0005262 | Not Cancer Driver | No | 277 | 0.251 | 99 | 25 | 0.253 | 0 |
| CACNB1 | CACNB1 | Q02641 | Voltage-dependent L-type calcium channel subunit beta-1 | chr17 | GO:0005262 | Not Cancer Driver | No | 75 | 0.125 | 396 | 47 | 0.119 | 0 |
| CACNB2 | CACNB2 | Q08289 | Voltage-dependent L-type calcium channel subunit beta-2 | chr10 | GO:0005262 | Not Cancer Driver | No | 155 | 0.235 | 478 | 106 | 0.222 | 0 |
| CACNB3 | CACNB3 | P54284 | Voltage-dependent L-type calcium channel subunit beta-3 | chr12 | GO:0005262 | Not Cancer Driver | No | 58 | 0.12 | 258 | 30 | 0.116 | 0 |
| CACNB4 | CACNB4 | O00305 | Voltage-dependent L-type calcium channel subunit beta-4 | chr2 | GO:0005262 | Not Cancer Driver | No | 82 | 0.158 | 295 | 49 | 0.166 | 1 |
| CATSPER2_ENST00000396879 | CATSPER2 | Q96P56 | Cation channel sperm-associated protein 2 | chr15 | GO:0005262 | Not Cancer Driver | No | 73 | 0.138 | 103 | 10 | 0.097 | 0 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0005262 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CHRNA10 | CHRNA10 | Q9GZZ6 | Neuronal acetylcholine receptor subunit alpha-10 | chr11 | GO:0005262 | Not Cancer Driver | No | 65 | 0.144 | 34 | 5 | 0.147 | 0 |
| CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0005262 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
| CHRNA9 | CHRNA9 | Q9UGM1 | Neuronal acetylcholine receptor subunit alpha-9 | chr4 | GO:0005262 | Not Cancer Driver | No | 76 | 0.159 | 23 | 6 | 0.261 | 0 |
| CNR1_ENST00000549890 | CNR1 | P21554 | Cannabinoid receptor 1 | chr6 | GO:0005262 | Not Cancer Driver | No | 129 | 0.273 | 9 | 1 | 0.111 | 0 |
| CUL5 | CUL5 | Q93034 | Cullin-5 | chr11 | GO:0005262 | Not Cancer Driver | No | 97 | 0.124 | 5 | 1 | 0.2 | 0 |
| FAM155A | NALF1 | B1AL88 | NALCN channel auxiliary factor 1 | chr13 | GO:0005262 | Not Cancer Driver | No | 121 | 0.264 | 162 | 51 | 0.315 | 0 |
| FAM155B | NALF2 | O75949 | NALCN channel auxiliary factor 2 | chrX | GO:0005262 | Not Cancer Driver | No | 56 | 0.119 | 160 | 26 | 0.163 | 0 |
| FKBP1B | FKBP1B | P68106 | Peptidyl-prolyl cis-trans isomerase FKBP1B | chr2 | GO:0005262 | Not Cancer Driver | No | 10 | 0.093 | 58 | 4 | 0.069 | 0 |
| GPM6A_ENST00000393658 | GPM6A | P51674 | Neuronal membrane glycoprotein M6-a | chr4 | GO:0005262 | Not Cancer Driver | No | 83 | 0.299 | 15 | 5 | 0.333 | 0 |
| GRIN1_ENST00000371561 | GRIN1 | Q05586 | Glutamate receptor ionotropic, NMDA 1 | chr9 | GO:0005262 | Not Cancer Driver | No | 88 | 0.094 | 190 | 15 | 0.079 | 13 |
| GRIN2A_ENST00000330684 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0005262 | Census, Compendium | Yes | 528 | 0.361 | 506 | 207 | 0.409 | 31 |
| GRIN2B | GRIN2B | Q13224 | Glutamate receptor ionotropic, NMDA 2B | chr12 | GO:0005262 | Not Cancer Driver | No | 413 | 0.278 | 426 | 147 | 0.345 | 11 |
| GRIN2C | GRIN2C | Q14957 | Glutamate receptor ionotropic, NMDA 2C | chr17 | GO:0005262 | Not Cancer Driver | No | 111 | 0.09 | 276 | 6 | 0.022 | 0 |
| GRIN2D | GRIN2D | O15399 | Glutamate receptor ionotropic, NMDA 2D | chr19 | GO:0005262 | Not Cancer Driver | No | 125 | 0.094 | 467 | 15 | 0.032 | 1 |
| GRIN3A | GRIN3A | Q8TCU5 | Glutamate receptor ionotropic, NMDA 3A | chr9 | GO:0005262 | Not Cancer Driver | No | 308 | 0.276 | 179 | 22 | 0.123 | 0 |
| GRIN3B | GRIN3B | O60391 | Glutamate receptor ionotropic, NMDA 3B | chr19 | GO:0005262 | Not Cancer Driver | No | 90 | 0.086 | 299 | 23 | 0.077 | 0 |
| HTR1B | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | GO:0005262 | Not Cancer Driver | No | 91 | 0.233 | 33 | 15 | 0.455 | 0 |
| ITPR1_ENST00000354582 | ITPR1 | Q14643 | Inositol 1,4,5-trisphosphate receptor type 1 | chr3 | GO:0005262 | Not Cancer Driver | No | 390 | 0.141 | 581 | 76 | 0.131 | 6 |
| ITPR2 | ITPR2 | Q14571 | Inositol 1,4,5-trisphosphate receptor type 2 | chr12 | GO:0005262 | Not Cancer Driver | No | 359 | 0.133 | 394 | 57 | 0.145 | 1 |
| ITPR3 | ITPR3 | Q14573 | Inositol 1,4,5-trisphosphate receptor type 3 | chr6 | GO:0005262 | Not Cancer Driver | No | 336 | 0.126 | 385 | 44 | 0.114 | 0 |
| MCOLN1 | MCOLN1 | Q9GZU1 | Mucolipin-1 | chr19 | GO:0005262 | Not Cancer Driver | No | 77 | 0.133 | 63 | 15 | 0.238 | 7 |
| MCOLN2 | MCOLN2 | Q8IZK6 | Mucolipin-2 | chr1 | GO:0005262 | Not Cancer Driver | No | 93 | 0.164 | 0 | 0 | 0.0 | 0 |
| MCOLN3 | MCOLN3 | Q8TDD5 | Mucolipin-3 | chr1 | GO:0005262 | Not Cancer Driver | No | 102 | 0.184 | 9 | 2 | 0.222 | 0 |
| MCU | MCU | Q8NE86 | Calcium uniporter protein, mitochondrial | chr10 | GO:0005262 | Not Cancer Driver | No | 41 | 0.117 | 13 | 0 | 0.0 | 0 |
| ORAI1 | ORAI1 | Q96D31 | Calcium release-activated calcium channel protein 1 | chr12 | GO:0005262 | Not Cancer Driver | No | 26 | 0.086 | 101 | 9 | 0.089 | 5 |
| ORAI2 | ORAI2 | Q96SN7 | Protein orai-2 | chr7 | GO:0005262 | Not Cancer Driver | No | 34 | 0.134 | 23 | 3 | 0.13 | 0 |
| ORAI3 | ORAI3 | Q9BRQ5 | Protein orai-3 | chr16 | GO:0005262 | Not Cancer Driver | No | 31 | 0.105 | 93 | 12 | 0.129 | 0 |
| P2RX4_ENST00000337233 | P2RX4 | Q99571 | P2X purinoceptor 4 | chr12 | GO:0005262 | Not Cancer Driver | No | 36 | 0.093 | 0 | 0 | 0.0 | 0 |
| PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | GO:0005262 | Not Cancer Driver | No | 54 | 0.127 | 45 | 7 | 0.156 | 2 |
| PKD1 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0005262 | Not Cancer Driver | No | 393 | 0.091 | 690 | 66 | 0.096 | 92 |
| PKD1L1 | PKD1L1 | Q8TDX9 | Polycystic kidney disease protein 1-like 1 | chr7 | GO:0005262 | Not Cancer Driver | No | 492 | 0.173 | 518 | 97 | 0.187 | 1 |
| PKD1L3 | PKD1L3 | Q7Z443 | Polycystic kidney disease protein 1-like 3 | chr16 | GO:0005262 | Not Cancer Driver | No | 97 | 0.056 | 145 | 9 | 0.062 | 0 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0005262 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| PKD2L1 | PKD2L1 | Q9P0L9 | Polycystic kidney disease 2-like 1 protein | chr10 | GO:0005262 | Not Cancer Driver | No | 135 | 0.168 | 180 | 32 | 0.178 | 0 |
| PKD2L2 | PKD2L2 | Q9NZM6 | Polycystic kidney disease 2-like 2 protein | chr5 | GO:0005262 | Not Cancer Driver | No | 88 | 0.141 | 25 | 8 | 0.32 | 0 |
| PKDREJ | PKDREJ | Q9NTG1 | Polycystic kidney disease and receptor for egg jelly-related protein | chr22 | GO:0005262 | Not Cancer Driver | No | 287 | 0.127 | 195 | 35 | 0.179 | 0 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0005262 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
| RASA3 | RASA3 | Q14644 | Ras GTPase-activating protein 3 | chr13 | GO:0005262 | Not Cancer Driver | No | 118 | 0.141 | 101 | 19 | 0.188 | 0 |
| RYR1 | RYR1 | P21817 | Ryanodine receptor 1 | chr19 | GO:0005262 | Not Cancer Driver | No | 1003 | 0.199 | 1186 | 233 | 0.196 | 154 |
| RYR2 | RYR2 | Q92736 | Ryanodine receptor 2 | chr1 | GO:0005262 | Not Cancer Driver | No | 1703 | 0.343 | 782 | 281 | 0.359 | 51 |
| RYR3 | RYR3 | Q15413 | Ryanodine receptor 3 | chr15 | GO:0005262 | Not Cancer Driver | No | 1079 | 0.222 | 649 | 162 | 0.25 | 0 |
| SEC61A1 | SEC61A1 | P61619 | Protein transport protein Sec61 subunit alpha isoform 1 | chr3 | GO:0005262 | Not Cancer Driver | No | 57 | 0.12 | 0 | 0 | 0.0 | 2 |
| SLC24A1 | SLC24A1 | O60721 | Sodium/potassium/calcium exchanger 1 | chr15 | GO:0005262 | Not Cancer Driver | No | 105 | 0.096 | 595 | 53 | 0.089 | 0 |
| SLC24A2 | SLC24A2 | Q9UI40 | Sodium/potassium/calcium exchanger 2 | chr9 | GO:0005262 | Not Cancer Driver | No | 120 | 0.182 | 144 | 24 | 0.167 | 0 |
| SLC24A3 | SLC24A3 | Q9HC58 | Sodium/potassium/calcium exchanger 3 | chr20 | GO:0005262 | Not Cancer Driver | No | 143 | 0.222 | 120 | 45 | 0.375 | 0 |
| SLC24A4 | SLC24A4 | Q8NFF2 | Sodium/potassium/calcium exchanger 4 | chr14 | GO:0005262 | Not Cancer Driver | No | 121 | 0.195 | 85 | 14 | 0.165 | 2 |
| SLC24A5 | SLC24A5 | Q71RS6 | Sodium/potassium/calcium exchanger 5 | chr15 | GO:0005262 | Not Cancer Driver | No | 79 | 0.158 | 7 | 2 | 0.286 | 0 |
| STIM2_ENST00000467087 | STIM2 | Q9P246 | Stromal interaction molecule 2 | chr4 | GO:0005262 | Not Cancer Driver | No | 82 | 0.11 | 387 | 45 | 0.116 | 0 |
| TMCO1 | TMCO1 | Q9UM00 | Calcium load-activated calcium channel | chr1 | GO:0005262 | Not Cancer Driver | No | 31 | 0.13 | 49 | 5 | 0.102 | 0 |
| TMEM37 | TMEM37 | Q8WXS4 | Voltage-dependent calcium channel gamma-like subunit | chr2 | GO:0005262 | Not Cancer Driver | No | 34 | 0.179 | 0 | 0 | 0.0 | 0 |
| TPCN1_ENST00000335509 | TPCN1 | Q9ULQ1 | Two pore channel protein 1 | chr12 | GO:0005262 | Not Cancer Driver | No | 114 | 0.14 | 99 | 18 | 0.182 | 0 |
| TPCN2 | TPCN2 | Q8NHX9 | Two pore channel protein 2 | chr11 | GO:0005262 | Not Cancer Driver | No | 73 | 0.097 | 16 | 0 | 0.0 | 0 |
| TRPA1 | TRPA1 | O75762 | Transient receptor potential cation channel subfamily A member 1 | chr8 | GO:0005262 | Not Cancer Driver | No | 324 | 0.29 | 62 | 14 | 0.226 | 1 |
| TRPC1 | TRPC1 | P48995 | Short transient receptor potential channel 1 | chr3 | GO:0005262 | Not Cancer Driver | No | 143 | 0.18 | 52 | 11 | 0.212 | 0 |
| TRPC3_ENST00000264811 | TRPC3 | Q13507 | Short transient receptor potential channel 3 | chr4 | GO:0005262 | Not Cancer Driver | No | 200 | 0.239 | 23 | 2 | 0.087 | 1 |
| TRPC4AP | TRPC4AP | Q8TEL6 | Short transient receptor potential channel 4-associated protein | chr20 | GO:0005262 | Not Cancer Driver | No | 84 | 0.105 | 70 | 7 | 0.1 | 0 |
| TRPC4_ENST00000379705 | TRPC4 | Q9UBN4 | Short transient receptor potential channel 4 | chr13 | GO:0005262 | Not Cancer Driver | No | 322 | 0.33 | 195 | 66 | 0.338 | 0 |
| TRPC5 | TRPC5 | Q9UL62 | Short transient receptor potential channel 5 | chrX | GO:0005262 | Not Cancer Driver | No | 255 | 0.262 | 148 | 32 | 0.216 | 0 |
| TRPC6 | TRPC6 | Q9Y210 | Short transient receptor potential channel 6 | chr11 | GO:0005262 | Not Cancer Driver | No | 202 | 0.217 | 165 | 46 | 0.279 | 10 |
| TRPC7 | TRPC7 | Q9HCX4 | Short transient receptor potential channel 7 | chr5 | GO:0005262 | Not Cancer Driver | No | 224 | 0.26 | 106 | 39 | 0.368 | 0 |
| TRPM1_ENST00000397795 | TRPM1 | Q7Z4N2 | Transient receptor potential cation channel subfamily M member 1 | chr15 | GO:0005262 | Not Cancer Driver | No | 254 | 0.158 | 516 | 74 | 0.143 | 12 |
| TRPM2_ENST00000397928 | TRPM2 | O94759 | Transient receptor potential cation channel subfamily M member 2 | chr21 | GO:0005262 | Not Cancer Driver | No | 286 | 0.19 | 266 | 44 | 0.165 | 0 |
| TRPM3 | TRPM3 | Q9HCF6 | Transient receptor potential cation channel subfamily M member 3 | chr9 | GO:0005262 | Not Cancer Driver | No | 369 | 0.213 | 480 | 108 | 0.225 | 0 |
| TRPM4 | TRPM4 | Q8TD43 | Transient receptor potential cation channel subfamily M member 4 | chr19 | GO:0005262 | Not Cancer Driver | No | 152 | 0.125 | 149 | 18 | 0.121 | 12 |
| TRPM5 | TRPM5 | Q9NZQ8 | Transient receptor potential cation channel subfamily M member 5 | chr11 | GO:0005262 | Not Cancer Driver | No | 123 | 0.106 | 186 | 19 | 0.102 | 0 |
| TRPM6 | TRPM6 | Q9BX84 | Transient receptor potential cation channel subfamily M member 6 | chr9 | GO:0005262 | Not Cancer Driver | No | 431 | 0.213 | 458 | 99 | 0.216 | 6 |
| TRPM7 | TRPM7 | Q96QT4 | Transient receptor potential cation channel subfamily M member 7 | chr15 | GO:0005262 | Not Cancer Driver | No | 199 | 0.107 | 455 | 60 | 0.132 | 0 |
| TRPM8 | TRPM8 | Q7Z2W7 | Transient receptor potential cation channel subfamily M member 8 | chr2 | GO:0005262 | Not Cancer Driver | No | 206 | 0.187 | 43 | 11 | 0.256 | 0 |
| TRPV1_ENST00000399756 | TRPV1 | Q8NER1 | Transient receptor potential cation channel subfamily V member 1 | chr17 | GO:0005262 | Not Cancer Driver | No | 93 | 0.111 | 155 | 18 | 0.116 | 0 |
| TRPV2 | TRPV2 | Q9Y5S1 | Transient receptor potential cation channel subfamily V member 2 | chr17 | GO:0005262 | Not Cancer Driver | No | 105 | 0.137 | 175 | 23 | 0.131 | 0 |
| TRPV3_ENST00000576742 | TRPV3 | Q8NET8 | Transient receptor potential cation channel subfamily V member 3 | chr17 | GO:0005262 | Not Cancer Driver | No | 127 | 0.161 | 177 | 36 | 0.203 | 4 |
| TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0005262 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |
| TRPV5 | TRPV5 | Q9NQA5 | Transient receptor potential cation channel subfamily V member 5 | chr7 | GO:0005262 | Not Cancer Driver | No | 206 | 0.283 | 68 | 14 | 0.206 | 0 |
| TRPV6 | TRPV6 | Q9H1D0 | Transient receptor potential cation channel subfamily V member 6 | chr7 | GO:0005262 | Not Cancer Driver | No | 183 | 0.239 | 77 | 20 | 0.26 | 6 |
| TSPOAP1 | TSPOAP1 | O95153 | Peripheral-type benzodiazepine receptor-associated protein 1 | chr17 | GO:0005262 | Not Cancer Driver | No | 268 | 0.144 | 1522 | 213 | 0.14 | 0 |