Total number of protein in "GO:0004867" GO term: 94
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A2M | A2M | P01023 | Alpha-2-macroglobulin | chr12 | GO:0004867 | Not Cancer Driver | No | 260 | 0.176 | 144 | 22 | 0.153 | 0 |
| A2ML1 | A2ML1 | A8K2U0 | Alpha-2-macroglobulin-like protein 1 | chr12 | GO:0004867 | Not Cancer Driver | No | 269 | 0.185 | 97 | 22 | 0.227 | 0 |
| AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0004867 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
| AMBP | AMBP | P02760 | Protein AMBP | chr9 | GO:0004867 | Not Cancer Driver | No | 57 | 0.162 | 61 | 15 | 0.246 | 0 |
| ANOS1 | ANOS1 | P23352 | Anosmin-1 | chrX | GO:0004867 | Not Cancer Driver | No | 124 | 0.182 | 195 | 44 | 0.226 | 14 |
| ANXA2_ENST00000396024 | ANXA2 | P07355 | Annexin A2 | chr15 | GO:0004867 | Not Cancer Driver | No | 49 | 0.145 | 20 | 4 | 0.2 | 0 |
| APLP2 | APLP2 | Q06481 | Amyloid beta precursor like protein 2 | chr11 | GO:0004867 | Not Cancer Driver | No | 96 | 0.126 | 393 | 48 | 0.122 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0004867 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| CD109 | CD109 | Q6YHK3 | CD109 antigen | chr6 | GO:0004867 | Not Cancer Driver | No | 204 | 0.141 | 54 | 11 | 0.204 | 0 |
| COL28A1 | COL28A1 | Q2UY09 | Collagen alpha-1(XXVIII) chain | chr7 | GO:0004867 | Not Cancer Driver | No | 196 | 0.174 | 671 | 146 | 0.218 | 0 |
| COL6A3 | COL6A3 | P12111 | Collagen alpha-3(VI) chain | chr2 | GO:0004867 | Not Cancer Driver | No | 690 | 0.217 | 696 | 146 | 0.21 | 14 |
| COL7A1 | COL7A1 | Q02388 | Collagen alpha-1(VII) chain | chr3 | GO:0004867 | Not Cancer Driver | No | 462 | 0.157 | 2303 | 397 | 0.172 | 77 |
| CPAMD8 | CPAMD8 | Q8IZJ3 | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 | chr19 | GO:0004867 | Not Cancer Driver | No | 349 | 0.185 | 354 | 56 | 0.158 | 1 |
| CRIM1 | CRIM1 | Q9NZV1 | Cysteine-rich motor neuron 1 protein | chr2 | GO:0004867 | Not Cancer Driver | No | 133 | 0.128 | 35 | 4 | 0.114 | 0 |
| EPPIN | EPPIN | O95925 | Eppin | chr20 | GO:0004867 | Not Cancer Driver | No | 18 | 0.135 | 0 | 0 | 0.0 | 0 |
| FURIN_ENST00000610579 | FURIN | P09958 | Furin | chr15 | GO:0004867 | Not Cancer Driver | No | 93 | 0.117 | 283 | 35 | 0.124 | 0 |
| HRG | HRG | P04196 | Histidine-rich glycoprotein | chr3 | GO:0004867 | Not Cancer Driver | No | 121 | 0.23 | 277 | 75 | 0.271 | 2 |
| ITIH1 | ITIH1 | P19827 | Inter-alpha-trypsin inhibitor heavy chain H1 | chr3 | GO:0004867 | Not Cancer Driver | No | 166 | 0.182 | 180 | 48 | 0.267 | 0 |
| ITIH2 | ITIH2 | P19823 | Inter-alpha-trypsin inhibitor heavy chain H2 | chr10 | GO:0004867 | Not Cancer Driver | No | 204 | 0.216 | 110 | 24 | 0.218 | 0 |
| ITIH3 | ITIH3 | Q06033 | Inter-alpha-trypsin inhibitor heavy chain H3 | chr3 | GO:0004867 | Not Cancer Driver | No | 122 | 0.137 | 171 | 25 | 0.146 | 0 |
| ITIH4 | ITIH4 | Q14624 | Inter-alpha-trypsin inhibitor heavy chain H4 | chr3 | GO:0004867 | Not Cancer Driver | No | 103 | 0.111 | 264 | 39 | 0.148 | 0 |
| ITIH5_ENST00000397146 | ITIH5 | Q86UX2 | Inter-alpha-trypsin inhibitor heavy chain H5 | chr10 | GO:0004867 | Not Cancer Driver | No | 224 | 0.238 | 238 | 73 | 0.307 | 0 |
| ITIH6 | ITIH6 | Q6UXX5 | Inter-alpha-trypsin inhibitor heavy chain H6 | chrX | GO:0004867 | Not Cancer Driver | No | 257 | 0.196 | 528 | 119 | 0.225 | 0 |
| PAPLN_ENST00000644200 | PAPLN | O95428 | Papilin | chr14 | GO:0004867 | Not Cancer Driver | No | 175 | 0.137 | 572 | 74 | 0.129 | 0 |
| PCSK1N | PCSK1N | Q9UHG2 | ProSAAS | chrX | GO:0004867 | Not Cancer Driver | No | 7 | 0.027 | 187 | 7 | 0.037 | 0 |
| PEBP1 | PEBP1 | P30086 | Phosphatidylethanolamine-binding protein 1 | chr12 | GO:0004867 | Not Cancer Driver | No | 23 | 0.123 | 76 | 13 | 0.171 | 0 |
| PI3 | PI3 | P19957 | Elafin | chr20 | GO:0004867 | Not Cancer Driver | No | 31 | 0.265 | 35 | 7 | 0.2 | 0 |
| PZP | PZP | P20742 | Pregnancy zone protein | chr12 | GO:0004867 | Not Cancer Driver | No | 279 | 0.188 | 101 | 21 | 0.208 | 0 |
| RECK | RECK | O95980 | Reversion-inducing cysteine-rich protein with Kazal motifs | chr9 | GO:0004867 | Not Cancer Driver | No | 115 | 0.118 | 9 | 2 | 0.222 | 0 |
| SERPINA1 | SERPINA1 | P01009 | Alpha-1-antitrypsin | chr14 | GO:0004867 | Not Cancer Driver | No | 66 | 0.158 | 38 | 7 | 0.184 | 0 |
| SERPINA10 | SERPINA10 | Q9UK55 | Protein Z-dependent protease inhibitor | chr14 | GO:0004867 | Not Cancer Driver | No | 108 | 0.243 | 74 | 18 | 0.243 | 0 |
| SERPINA11 | SERPINA11 | Q86U17 | Serpin A11 | chr14 | GO:0004867 | Not Cancer Driver | No | 91 | 0.216 | 58 | 15 | 0.259 | 0 |
| SERPINA12 | SERPINA12 | Q8IW75 | Serpin A12 | chr14 | GO:0004867 | Not Cancer Driver | No | 90 | 0.217 | 22 | 3 | 0.136 | 0 |
| SERPINA3_ENST00000393080 | SERPINA3 | P01011 | Alpha-1-antichymotrypsin | chr14 | GO:0004867 | Not Cancer Driver | No | 117 | 0.277 | 18 | 10 | 0.556 | 0 |
| SERPINA4_ENST00000298841 | SERPINA4 | P29622 | Kallistatin | chr14 | GO:0004867 | Not Cancer Driver | No | 114 | 0.267 | 19 | 4 | 0.211 | 0 |
| SERPINA5_ENST00000554276 | SERPINA5 | P05154 | Plasma serine protease inhibitor | chr14 | GO:0004867 | Not Cancer Driver | No | 103 | 0.254 | 24 | 17 | 0.708 | 0 |
| SERPINA6 | SERPINA6 | P08185 | Corticosteroid-binding globulin | chr14 | GO:0004867 | Not Cancer Driver | No | 85 | 0.21 | 0 | 0 | 0.0 | 2 |
| SERPINA7 | SERPINA7 | P05543 | Thyroxine-binding globulin | chrX | GO:0004867 | Not Cancer Driver | No | 108 | 0.26 | 11 | 2 | 0.182 | 0 |
| SERPINA9_ENST00000380365 | SERPINA9 | Q86WD7 | Serpin A9 | chr14 | GO:0004867 | Not Cancer Driver | No | 96 | 0.23 | 25 | 6 | 0.24 | 0 |
| SERPINB1 | SERPINB1 | P30740 | Leukocyte elastase inhibitor | chr6 | GO:0004867 | Not Cancer Driver | No | 39 | 0.103 | 14 | 0 | 0.0 | 0 |
| SERPINB10_ENST00000619595 | SERPINB10 | P48595 | Serpin B10 | chr18 | GO:0004867 | Not Cancer Driver | No | 65 | 0.164 | 43 | 8 | 0.186 | 0 |
| SERPINB11_ENST00000544088 | SERPINB11 | Q96P15 | Serpin B11 | chr18 | GO:0004867 | Not Cancer Driver | No | 97 | 0.247 | 17 | 2 | 0.118 | 0 |
| SERPINB12_ENST00000269491 | SERPINB12 | Q96P63 | Serpin B12 | chr18 | GO:0004867 | Not Cancer Driver | No | 82 | 0.202 | 21 | 6 | 0.286 | 0 |
| SERPINB13_ENST00000344731 | SERPINB13 | Q9UIV8 | Serpin B13 | chr18 | GO:0004867 | Not Cancer Driver | No | 84 | 0.215 | 55 | 16 | 0.291 | 0 |
| SERPINB2_ENST00000299502 | SERPINB2 | P05120 | Plasminogen activator inhibitor 2 | chr18 | GO:0004867 | Not Cancer Driver | No | 100 | 0.241 | 29 | 7 | 0.241 | 0 |
| SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | GO:0004867 | Not Cancer Driver | No | 142 | 0.364 | 47 | 28 | 0.596 | 0 |
| SERPINB4 | SERPINB4 | P48594 | Serpin B4 | chr18 | GO:0004867 | Not Cancer Driver | No | 120 | 0.308 | 48 | 18 | 0.375 | 0 |
| SERPINB5 | SERPINB5 | P36952 | Serpin B5 | chr18 | GO:0004867 | Not Cancer Driver | No | 57 | 0.152 | 50 | 7 | 0.14 | 0 |
| SERPINB6_ENST00000644388 | SERPINB6 | P35237 | Serpin B6 | chr6 | GO:0004867 | Not Cancer Driver | No | 47 | 0.125 | 8 | 0 | 0.0 | 0 |
| SERPINB7 | SERPINB7 | O75635 | Serpin B7 | chr18 | GO:0004867 | Not Cancer Driver | No | 100 | 0.263 | 30 | 8 | 0.267 | 0 |
| SERPINB8 | SERPINB8 | P50452 | Serpin B8 | chr18 | GO:0004867 | Not Cancer Driver | No | 74 | 0.198 | 4 | 0 | 0.0 | 0 |
| SERPINB9 | SERPINB9 | P50453 | Serpin B9 | chr6 | GO:0004867 | Not Cancer Driver | No | 64 | 0.17 | 22 | 2 | 0.091 | 0 |
| SERPINC1 | SERPINC1 | P01008 | Antithrombin-III | chr1 | GO:0004867 | Not Cancer Driver | No | 84 | 0.181 | 29 | 8 | 0.276 | 84 |
| SERPIND1_ENST00000406799 | SERPIND1 | P05546 | Heparin cofactor 2 | chr22 | GO:0004867 | Not Cancer Driver | No | 69 | 0.138 | 50 | 7 | 0.14 | 3 |
| SERPINE1 | SERPINE1 | P05121 | Plasminogen activator inhibitor 1 | chr7 | GO:0004867 | Not Cancer Driver | No | 78 | 0.194 | 7 | 2 | 0.286 | 0 |
| SERPINE2_ENST00000258405 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0004867 | Not Cancer Driver | No | 62 | 0.156 | 0 | 0 | 0.0 | 0 |
| SERPINE3 | SERPINE3 | A8MV23 | Serpin E3 | chr13 | GO:0004867 | Not Cancer Driver | No | 60 | 0.142 | 41 | 7 | 0.171 | 0 |
| SERPINF1 | SERPINF1 | P36955 | Pigment epithelium-derived factor | chr17 | GO:0004867 | Not Cancer Driver | No | 51 | 0.122 | 57 | 5 | 0.088 | 0 |
| SERPINF2_ENST00000382061 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0004867 | Not Cancer Driver | No | 62 | 0.126 | 112 | 21 | 0.188 | 1 |
| SERPING1 | SERPING1 | P05155 | Plasma protease C1 inhibitor | chr11 | GO:0004867 | Not Cancer Driver | No | 74 | 0.148 | 113 | 13 | 0.115 | 40 |
| SERPINH1_ENST00000358171 | SERPINH1 | P50454 | Serpin H1 | chr11 | GO:0004867 | Not Cancer Driver | No | 51 | 0.122 | 52 | 6 | 0.115 | 1 |
| SERPINI1 | SERPINI1 | Q99574 | Neuroserpin | chr3 | GO:0004867 | Not Cancer Driver | No | 77 | 0.188 | 21 | 6 | 0.286 | 2 |
| SERPINI2_ENST00000476257 | SERPINI2 | O75830 | Serpin I2 | chr3 | GO:0004867 | Not Cancer Driver | No | 116 | 0.286 | 21 | 10 | 0.476 | 0 |
| SLPI | SLPI | P03973 | Antileukoproteinase | chr20 | GO:0004867 | Not Cancer Driver | No | 20 | 0.152 | 0 | 0 | 0.0 | 0 |
| SPINK1 | SPINK1 | P00995 | Serine protease inhibitor Kazal-type 1 | chr5 | GO:0004867 | Not Cancer Driver | No | 14 | 0.177 | 0 | 0 | 0.0 | 3 |
| SPINK13 | SPINK13 | Q1W4C9 | Serine protease inhibitor Kazal-type 13 | chr5 | GO:0004867 | Not Cancer Driver | No | 24 | 0.255 | 0 | 0 | 0.0 | 0 |
| SPINK14 | SPINK14 | Q6IE38 | Serine protease inhibitor Kazal-type 14 | chr5 | GO:0004867 | Not Cancer Driver | No | 19 | 0.196 | 0 | 0 | 0.0 | 0 |
| SPINK2_ENST00000248701 | SPINK2 | P20155 | Serine protease inhibitor Kazal-type 2 | chr4 | GO:0004867 | Not Cancer Driver | No | 10 | 0.119 | 0 | 0 | 0.0 | 0 |
| SPINK4 | SPINK4 | O60575 | Serine protease inhibitor Kazal-type 4 | chr9 | GO:0004867 | Not Cancer Driver | No | 19 | 0.221 | 0 | 0 | 0.0 | 0 |
| SPINK5_ENST00000256084 | SPINK5 | Q9NQ38 | Serine protease inhibitor Kazal-type 5 | chr5 | GO:0004867 | Not Cancer Driver | No | 168 | 0.158 | 590 | 102 | 0.173 | 0 |
| SPINK6_ENST00000621437 | SPINK6 | Q6UWN8 | Serine protease inhibitor Kazal-type 6 | chr5 | GO:0004867 | Not Cancer Driver | No | 17 | 0.212 | 0 | 0 | 0.0 | 0 |
| SPINK7 | SPINK7 | P58062 | Serine protease inhibitor Kazal-type 7 | chr5 | GO:0004867 | Not Cancer Driver | No | 16 | 0.188 | 0 | 0 | 0.0 | 0 |
| SPINK8 | SPINK8 | P0C7L1 | Serine protease inhibitor Kazal-type 8 | chr3 | GO:0004867 | Not Cancer Driver | No | 8 | 0.082 | 0 | 0 | 0.0 | 0 |
| SPINK9 | SPINK9 | Q5DT21 | Serine protease inhibitor Kazal-type 9 | chr5 | GO:0004867 | Not Cancer Driver | No | 13 | 0.151 | 0 | 0 | 0.0 | 0 |
| SPINT1 | SPINT1 | O43278 | Kunitz-type protease inhibitor 1 | chr15 | GO:0004867 | Not Cancer Driver | No | 63 | 0.119 | 75 | 12 | 0.16 | 0 |
| SPINT2 | SPINT2 | O43291 | Kunitz-type protease inhibitor 2 | chr19 | GO:0004867 | Not Cancer Driver | No | 46 | 0.183 | 25 | 3 | 0.12 | 1 |
| SPINT3 | SPINT3 | P49223 | Kunitz-type protease inhibitor 3 | chr20 | GO:0004867 | Not Cancer Driver | No | 7 | 0.079 | 0 | 0 | 0.0 | 0 |
| SPINT4 | SPINT4 | Q6UDR6 | Kunitz-type protease inhibitor 4 | chr20 | GO:0004867 | Not Cancer Driver | No | 13 | 0.131 | 0 | 0 | 0.0 | 0 |
| SPOCK1 | SPOCK1 | Q08629 | Testican-1 | chr5 | GO:0004867 | Not Cancer Driver | No | 82 | 0.187 | 107 | 16 | 0.15 | 0 |
| TFPI | TFPI | P10646 | Tissue factor pathway inhibitor | chr2 | GO:0004867 | Not Cancer Driver | No | 47 | 0.155 | 28 | 2 | 0.071 | 0 |
| TFPI2 | TFPI2 | P48307 | Tissue factor pathway inhibitor 2 | chr7 | GO:0004867 | Not Cancer Driver | No | 54 | 0.23 | 5 | 11 | 2.2 | 0 |
| WFDC10A | WFDC10A | Q9H1F0 | WAP four-disulfide core domain protein 10A | chr20 | GO:0004867 | Not Cancer Driver | No | 16 | 0.203 | 0 | 0 | 0.0 | 0 |
| WFDC10B_ENST00000330523 | WFDC10B | Q8IUB3 | Protein WFDC10B | chr20 | GO:0004867 | Not Cancer Driver | No | 9 | 0.123 | 0 | 0 | 0.0 | 0 |
| WFDC11_ENST00000324384 | WFDC11 | Q8NEX6 | Protein WFDC11 | chr20 | GO:0004867 | Not Cancer Driver | No | 10 | 0.115 | 0 | 0 | 0.0 | 0 |
| WFDC12 | WFDC12 | Q8WWY7 | WAP four-disulfide core domain protein 12 | chr20 | GO:0004867 | Not Cancer Driver | No | 14 | 0.126 | 17 | 1 | 0.059 | 0 |
| WFDC13 | WFDC13 | Q8IUB5 | WAP four-disulfide core domain protein 13 | chr20 | GO:0004867 | Not Cancer Driver | No | 10 | 0.108 | 2 | 0 | 0.0 | 0 |
| WFDC1_ENST00000568638 | WFDC1 | Q9HC57 | WAP four-disulfide core domain protein 1 | chr16 | GO:0004867 | Not Cancer Driver | No | 17 | 0.077 | 92 | 6 | 0.065 | 0 |
| WFDC2 | WFDC2 | Q14508 | WAP four-disulfide core domain protein 2 | chr20 | GO:0004867 | Not Cancer Driver | No | 16 | 0.129 | 0 | 0 | 0.0 | 0 |
| WFDC3 | WFDC3 | Q8IUB2 | WAP four-disulfide core domain protein 3 | chr20 | GO:0004867 | Not Cancer Driver | No | 32 | 0.139 | 18 | 8 | 0.444 | 0 |
| WFDC5_ENST00000307971 | WFDC5 | Q8TCV5 | WAP four-disulfide core domain protein 5 | chr20 | GO:0004867 | Not Cancer Driver | No | 42 | 0.188 | 22 | 2 | 0.091 | 0 |
| WFDC8 | WFDC8 | Q8IUA0 | WAP four-disulfide core domain protein 8 | chr20 | GO:0004867 | Not Cancer Driver | No | 51 | 0.212 | 0 | 0 | 0.0 | 0 |
| WFDC9 | WFDC9 | Q8NEX5 | Protein WFDC9 | chr20 | GO:0004867 | Not Cancer Driver | No | 6 | 0.067 | 1 | 0 | 0.0 | 0 |
| WFIKKN1 | WFIKKN1 | Q96NZ8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 | chr16 | GO:0004867 | Not Cancer Driver | No | 38 | 0.069 | 90 | 4 | 0.044 | 0 |
| WFIKKN2 | WFIKKN2 | Q8TEU8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 | chr17 | GO:0004867 | Not Cancer Driver | No | 114 | 0.198 | 94 | 32 | 0.34 | 0 |