Total number of protein in "GO:0004866" GO term: 80
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A2M | A2M | P01023 | Alpha-2-macroglobulin | chr12 | GO:0004866 | Not Cancer Driver | No | 260 | 0.176 | 144 | 22 | 0.153 | 0 |
A2ML1 | A2ML1 | A8K2U0 | Alpha-2-macroglobulin-like protein 1 | chr12 | GO:0004866 | Not Cancer Driver | No | 269 | 0.185 | 97 | 22 | 0.227 | 0 |
AHSG | AHSG | P02765 | Alpha-2-HS-glycoprotein | chr3 | GO:0004866 | Not Cancer Driver | No | 74 | 0.202 | 131 | 41 | 0.313 | 0 |
AVP | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0004866 | Not Cancer Driver | No | 14 | 0.085 | 26 | 0 | 0.0 | 39 |
BIN1 | BIN1 | O00499 | Myc box-dependent-interacting protein 1 | chr2 | GO:0004866 | Not Cancer Driver | No | 65 | 0.11 | 456 | 42 | 0.092 | 5 |
BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0004866 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | GO:0004866 | Census, Compendium | Yes | 77 | 0.127 | 98 | 16 | 0.163 | 0 |
BIRC5_ENST00000350051 | BIRC5 | O15392 | Baculoviral IAP repeat-containing protein 5 | chr17 | GO:0004866 | Not Cancer Driver | No | 20 | 0.141 | 49 | 6 | 0.122 | 0 |
BIRC7 | BIRC7 | Q96CA5 | Baculoviral IAP repeat-containing protein 7 | chr20 | GO:0004866 | Not Cancer Driver | No | 52 | 0.174 | 136 | 22 | 0.162 | 0 |
BIRC8 | BIRC8 | Q96P09 | Baculoviral IAP repeat-containing protein 8 | chr19 | GO:0004866 | Not Cancer Driver | No | 79 | 0.335 | 39 | 10 | 0.256 | 0 |
BST2 | BST2 | Q10589 | Bone marrow stromal antigen 2 | chr19 | GO:0004866 | Not Cancer Driver | No | 19 | 0.106 | 20 | 0 | 0.0 | 0 |
C3 | C3 | P01024 | Complement C3 | chr19 | GO:0004866 | Not Cancer Driver | No | 337 | 0.203 | 287 | 50 | 0.174 | 12 |
C4A | C4A | P0C0L4 | Complement C4-A | chr6 | GO:0004866 | Not Cancer Driver | No | 43 | 0.025 | 309 | 6 | 0.019 | 0 |
C5 | C5 | P01031 | Complement C5 | chr9 | GO:0004866 | Not Cancer Driver | No | 192 | 0.115 | 84 | 9 | 0.107 | 0 |
CAST_ENST00000395813 | CAST | P20810 | Calpastatin | chr5 | GO:0004866 | Not Cancer Driver | No | 73 | 0.103 | 708 | 73 | 0.103 | 0 |
CD27 | CD27 | P26842 | CD27 antigen | chr12 | GO:0004866 | Not Cancer Driver | No | 30 | 0.115 | 92 | 11 | 0.12 | 1 |
COL4A3 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | GO:0004866 | Not Cancer Driver | No | 310 | 0.186 | 1433 | 277 | 0.193 | 13 |
CRB2 | CRB2 | Q5IJ48 | Protein crumbs homolog 2 | chr9 | GO:0004866 | Not Cancer Driver | No | 155 | 0.121 | 72 | 0 | 0.0 | 5 |
CST3_ENST00000376925 | CST3 | P01034 | Cystatin-C | chr20 | GO:0004866 | Not Cancer Driver | No | 17 | 0.116 | 31 | 1 | 0.032 | 2 |
CST7 | CST7 | O76096 | Cystatin-F | chr20 | GO:0004866 | Not Cancer Driver | No | 12 | 0.083 | 15 | 2 | 0.133 | 0 |
CSTB | CSTB | P04080 | Cystatin-B | chr21 | GO:0004866 | Not Cancer Driver | No | 7 | 0.071 | 40 | 0 | 0.0 | 1 |
DPEP1 | DPEP1 | P16444 | Dipeptidase 1 | chr16 | GO:0004866 | Not Cancer Driver | No | 54 | 0.131 | 41 | 6 | 0.146 | 0 |
FETUB_ENST00000450521 | FETUB | Q9UGM5 | Fetuin-B | chr3 | GO:0004866 | Not Cancer Driver | No | 76 | 0.199 | 119 | 30 | 0.252 | 0 |
GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | GO:0004866 | Not Cancer Driver | No | 39 | 0.116 | 24 | 3 | 0.125 | 0 |
GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0004866 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
HRG | HRG | P04196 | Histidine-rich glycoprotein | chr3 | GO:0004866 | Not Cancer Driver | No | 121 | 0.23 | 277 | 75 | 0.271 | 2 |
ITIH2 | ITIH2 | P19823 | Inter-alpha-trypsin inhibitor heavy chain H2 | chr10 | GO:0004866 | Not Cancer Driver | No | 204 | 0.216 | 110 | 24 | 0.218 | 0 |
ITIH3 | ITIH3 | Q06033 | Inter-alpha-trypsin inhibitor heavy chain H3 | chr3 | GO:0004866 | Not Cancer Driver | No | 122 | 0.137 | 171 | 25 | 0.146 | 0 |
ITIH4 | ITIH4 | Q14624 | Inter-alpha-trypsin inhibitor heavy chain H4 | chr3 | GO:0004866 | Not Cancer Driver | No | 103 | 0.111 | 264 | 39 | 0.148 | 0 |
KNG1 | KNG1 | P01042 | Kininogen-1 | chr3 | GO:0004866 | Not Cancer Driver | No | 130 | 0.202 | 294 | 66 | 0.224 | 1 |
LPA | LPA | P08519 | Apolipoprotein(a) | chr6 | GO:0004866 | Not Cancer Driver | No | 365 | 0.179 | 884 | 148 | 0.167 | 0 |
LXN | LXN | Q9BS40 | Latexin | chr3 | GO:0004866 | Not Cancer Driver | No | 21 | 0.095 | 91 | 9 | 0.099 | 0 |
MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0004866 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
NAIP_ENST00000194097 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0004866 | Not Cancer Driver | No | 39 | 0.028 | 67 | 4 | 0.06 | 0 |
NGF | NGF | P01138 | Beta-nerve growth factor | chr1 | GO:0004866 | Not Cancer Driver | No | 66 | 0.274 | 93 | 25 | 0.269 | 1 |
NLRP7_ENST00000590030 | NLRP7 | Q8WX94 | NACHT, LRR and PYD domains-containing protein 7 | chr19 | GO:0004866 | Not Cancer Driver | No | 300 | 0.306 | 71 | 20 | 0.282 | 9 |
NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0004866 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
OPRPN | OPRPN | Q99935 | Opiorphin prepropeptide | chr4 | GO:0004866 | Not Cancer Driver | No | 90 | 0.363 | 87 | 29 | 0.333 | 0 |
PCSK1N | PCSK1N | Q9UHG2 | ProSAAS | chrX | GO:0004866 | Not Cancer Driver | No | 7 | 0.027 | 187 | 7 | 0.037 | 0 |
PI3 | PI3 | P19957 | Elafin | chr20 | GO:0004866 | Not Cancer Driver | No | 31 | 0.265 | 35 | 7 | 0.2 | 0 |
PRDX3 | PRDX3 | P30048 | Thioredoxin-dependent peroxide reductase, mitochondrial | chr10 | GO:0004866 | Not Cancer Driver | No | 23 | 0.09 | 23 | 3 | 0.13 | 0 |
PRDX5 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | GO:0004866 | Not Cancer Driver | No | 22 | 0.103 | 0 | 0 | 0.0 | 0 |
PRNP | PRNP | P04156 | Major prion protein | chr20 | GO:0004866 | Not Cancer Driver | No | 36 | 0.142 | 115 | 7 | 0.061 | 18 |
PROS1 | PROS1 | P07225 | Vitamin K-dependent protein S | chr3 | GO:0004866 | Not Cancer Driver | No | 178 | 0.263 | 11 | 3 | 0.273 | 89 |
PSMF1_ENST00000333082 | PSMF1 | Q92530 | Proteasome inhibitor PI31 subunit | chr20 | GO:0004866 | Not Cancer Driver | No | 45 | 0.166 | 140 | 26 | 0.186 | 0 |
PZP | PZP | P20742 | Pregnancy zone protein | chr12 | GO:0004866 | Not Cancer Driver | No | 279 | 0.188 | 101 | 21 | 0.208 | 0 |
RARRES1 | RARRES1 | P49788 | Retinoic acid receptor responder protein 1 | chr3 | GO:0004866 | Not Cancer Driver | No | 24 | 0.082 | 79 | 3 | 0.038 | 0 |
RECK | RECK | O95980 | Reversion-inducing cysteine-rich protein with Kazal motifs | chr9 | GO:0004866 | Not Cancer Driver | No | 115 | 0.118 | 9 | 2 | 0.222 | 0 |
RENBP | RENBP | P51606 | N-acylglucosamine 2-epimerase | chrX | GO:0004866 | Not Cancer Driver | No | 65 | 0.152 | 64 | 10 | 0.156 | 0 |
ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0004866 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
RPS6KA1_ENST00000374168 | RPS6KA1 | Q15418 | Ribosomal protein S6 kinase alpha-1 | chr1 | GO:0004866 | Not Cancer Driver | No | 94 | 0.128 | 178 | 32 | 0.18 | 0 |
RPS6KA3_ENST00000379565 | RPS6KA3 | P51812 | Ribosomal protein S6 kinase alpha-3 | chrX | GO:0004866 | Compendium | Yes | 106 | 0.143 | 145 | 18 | 0.124 | 13 |
SERPINB9 | SERPINB9 | P50453 | Serpin B9 | chr6 | GO:0004866 | Not Cancer Driver | No | 64 | 0.17 | 22 | 2 | 0.091 | 0 |
SERPIND1_ENST00000406799 | SERPIND1 | P05546 | Heparin cofactor 2 | chr22 | GO:0004866 | Not Cancer Driver | No | 69 | 0.138 | 50 | 7 | 0.14 | 3 |
SERPINF2_ENST00000382061 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0004866 | Not Cancer Driver | No | 62 | 0.126 | 112 | 21 | 0.188 | 1 |
SLPI | SLPI | P03973 | Antileukoproteinase | chr20 | GO:0004866 | Not Cancer Driver | No | 20 | 0.152 | 0 | 0 | 0.0 | 0 |
SMR3A | SMR3A | Q99954 | Submaxillary gland androgen-regulated protein 3A | chr4 | GO:0004866 | Not Cancer Driver | No | 57 | 0.425 | 119 | 54 | 0.454 | 0 |
SMR3B_ENST00000614072 | SMR3B | P02814 | Submaxillary gland androgen-regulated protein 3B | chr4 | GO:0004866 | Not Cancer Driver | No | 29 | 0.367 | 65 | 27 | 0.415 | 0 |
SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0004866 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
SPINK1 | SPINK1 | P00995 | Serine protease inhibitor Kazal-type 1 | chr5 | GO:0004866 | Not Cancer Driver | No | 14 | 0.177 | 0 | 0 | 0.0 | 3 |
SPINK2_ENST00000248701 | SPINK2 | P20155 | Serine protease inhibitor Kazal-type 2 | chr4 | GO:0004866 | Not Cancer Driver | No | 10 | 0.119 | 0 | 0 | 0.0 | 0 |
SPINT2 | SPINT2 | O43291 | Kunitz-type protease inhibitor 2 | chr19 | GO:0004866 | Not Cancer Driver | No | 46 | 0.183 | 25 | 3 | 0.12 | 1 |
SPOCK1 | SPOCK1 | Q08629 | Testican-1 | chr5 | GO:0004866 | Not Cancer Driver | No | 82 | 0.187 | 107 | 16 | 0.15 | 0 |
SPOCK2_ENST00000317376 | SPOCK2 | Q92563 | Testican-2 | chr10 | GO:0004866 | Not Cancer Driver | No | 48 | 0.113 | 113 | 8 | 0.071 | 0 |
SPOCK3_ENST00000511531 | SPOCK3 | Q9BQ16 | Testican-3 | chr4 | GO:0004866 | Not Cancer Driver | No | 132 | 0.303 | 68 | 38 | 0.559 | 0 |
SPP2 | SPP2 | Q13103 | Secreted phosphoprotein 24 | chr2 | GO:0004866 | Not Cancer Driver | No | 49 | 0.232 | 26 | 3 | 0.115 | 0 |
TFPI | TFPI | P10646 | Tissue factor pathway inhibitor | chr2 | GO:0004866 | Not Cancer Driver | No | 47 | 0.155 | 28 | 2 | 0.071 | 0 |
TIMP1 | TIMP1 | P01033 | Metalloproteinase inhibitor 1 | chrX | GO:0004866 | Not Cancer Driver | No | 25 | 0.121 | 0 | 0 | 0.0 | 0 |
TIMP2 | TIMP2 | P16035 | Metalloproteinase inhibitor 2 | chr17 | GO:0004866 | Not Cancer Driver | No | 31 | 0.141 | 6 | 2 | 0.333 | 0 |
TIMP3 | TIMP3 | P35625 | Metalloproteinase inhibitor 3 | chr22 | GO:0004866 | Not Cancer Driver | No | 43 | 0.204 | 3 | 1 | 0.333 | 5 |
TIMP4 | TIMP4 | Q99727 | Metalloproteinase inhibitor 4 | chr3 | GO:0004866 | Not Cancer Driver | No | 30 | 0.134 | 8 | 2 | 0.25 | 0 |
TNFAIP8_ENST00000504771 | TNFAIP8 | O95379 | Tumor necrosis factor alpha-induced protein 8 | chr5 | GO:0004866 | Not Cancer Driver | No | 21 | 0.106 | 13 | 1 | 0.077 | 0 |
TNFSF14 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:0004866 | Not Cancer Driver | No | 58 | 0.242 | 18 | 1 | 0.056 | 0 |
UCHL5 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | GO:0004866 | Not Cancer Driver | No | 33 | 0.1 | 41 | 7 | 0.171 | 0 |
USP14 | USP14 | P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | chr18 | GO:0004866 | Not Cancer Driver | No | 59 | 0.119 | 86 | 6 | 0.07 | 0 |
VIL1 | VIL1 | P09327 | Villin-1 | chr2 | GO:0004866 | Not Cancer Driver | No | 124 | 0.15 | 222 | 38 | 0.171 | 0 |
WFDC2 | WFDC2 | Q14508 | WAP four-disulfide core domain protein 2 | chr20 | GO:0004866 | Not Cancer Driver | No | 16 | 0.129 | 0 | 0 | 0.0 | 0 |
WFIKKN1 | WFIKKN1 | Q96NZ8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 | chr16 | GO:0004866 | Not Cancer Driver | No | 38 | 0.069 | 90 | 4 | 0.044 | 0 |
WFIKKN2 | WFIKKN2 | Q8TEU8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 | chr17 | GO:0004866 | Not Cancer Driver | No | 114 | 0.198 | 94 | 32 | 0.34 | 0 |
XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0004866 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |