Total number of protein in "GO:0004860" GO term: 69
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CAMK2N1 | CAMK2N1 | Q7Z7J9 | Calcium/calmodulin-dependent protein kinase II inhibitor 1 | chr1 | GO:0004860 | Not Cancer Driver | No | 10 | 0.128 | 72 | 9 | 0.125 | 0 |
CAMK2N2 | CAMK2N2 | Q96S95 | Calcium/calmodulin-dependent protein kinase II inhibitor 2 | chr3 | GO:0004860 | Not Cancer Driver | No | 6 | 0.076 | 74 | 5 | 0.068 | 0 |
CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0004860 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0004860 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0004860 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
CDKN1C | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | GO:0004860 | Not Cancer Driver | No | 2 | 0.006 | 256 | 1 | 0.004 | 7 |
CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | GO:0004860 | Census, Compendium | Yes | 166 | 1.064 | 83 | 88 | 1.06 | 36 |
CDKN2B | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | GO:0004860 | Not Cancer Driver | No | 15 | 0.109 | 67 | 3 | 0.045 | 0 |
CDKN2C_ENST00000371761 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | GO:0004860 | Census, Compendium | Yes | 23 | 0.137 | 49 | 6 | 0.122 | 0 |
CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:0004860 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
CHP1 | CHP1 | Q99653 | Calcineurin B homologous protein 1 | chr15 | GO:0004860 | Not Cancer Driver | No | 27 | 0.138 | 70 | 12 | 0.171 | 0 |
CIB1_ENST00000328649 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0004860 | Not Cancer Driver | No | 24 | 0.126 | 6 | 1 | 0.167 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | GO:0004860 | Not Cancer Driver | No | 284 | 0.14 | 1017 | 160 | 0.157 | 3 |
DNAJC3 | DNAJC3 | Q13217 | DnaJ homolog subfamily C member 3 | chr13 | GO:0004860 | Not Cancer Driver | No | 60 | 0.119 | 131 | 17 | 0.13 | 0 |
DUS2 | DUS2 | Q9NX74 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | chr16 | GO:0004860 | Not Cancer Driver | No | 48 | 0.097 | 117 | 10 | 0.085 | 0 |
DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0004860 | Not Cancer Driver | No | 34 | 0.157 | 15 | 5 | 0.333 | 0 |
FGFR1OP | CEP43 | O95684 | Centrosomal protein 43 | chr6 | GO:0004860 | Not Cancer Driver | No | 43 | 0.108 | 272 | 33 | 0.121 | 0 |
GMFB | GMFB | P60983 | Glia maturation factor beta | chr14 | GO:0004860 | Not Cancer Driver | No | 18 | 0.127 | 11 | 0 | 0.0 | 0 |
GMFG | GMFG | O60234 | Glia maturation factor gamma | chr19 | GO:0004860 | Not Cancer Driver | No | 22 | 0.155 | 10 | 0 | 0.0 | 0 |
GSKIP_ENST00000438650 | GSKIP | Q9P0R6 | GSK3B-interacting protein | chr14 | GO:0004860 | Not Cancer Driver | No | 11 | 0.079 | 32 | 1 | 0.031 | 0 |
H2AFY | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:0004860 | Not Cancer Driver | No | 46 | 0.124 | 125 | 19 | 0.152 | 0 |
HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | GO:0004860 | Not Cancer Driver | No | 40 | 0.111 | 352 | 40 | 0.114 | 0 |
HEXIM2_ENST00000592695 | HEXIM2 | Q96MH2 | Protein HEXIM2 | chr17 | GO:0004860 | Not Cancer Driver | No | 35 | 0.122 | 286 | 35 | 0.122 | 0 |
HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0004860 | Not Cancer Driver | No | 10 | 0.049 | 118 | 8 | 0.068 | 20 |
HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0004860 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
IBTK | IBTK | Q9P2D0 | Inhibitor of Bruton tyrosine kinase | chr6 | GO:0004860 | Not Cancer Driver | No | 146 | 0.108 | 364 | 39 | 0.107 | 0 |
INCA1_ENST00000576820 | INCA1 | Q0VD86 | Protein INCA1 | chr17 | GO:0004860 | Not Cancer Driver | No | 18 | 0.076 | 195 | 14 | 0.072 | 0 |
INKA1 | INKA1 | Q96EL1 | PAK4-inhibitor INKA1 | chr3 | GO:0004860 | Not Cancer Driver | No | 40 | 0.139 | 227 | 36 | 0.159 | 0 |
INKA2 | INKA2 | Q9NTI7 | PAK4-inhibitor INKA2 | chr1 | GO:0004860 | Not Cancer Driver | No | 41 | 0.138 | 271 | 38 | 0.14 | 0 |
ITPRIP_ENST00000358187 | ITPRIP | Q8IWB1 | Inositol 1,4,5-trisphosphate receptor-interacting protein | chr10 | GO:0004860 | Not Cancer Driver | No | 62 | 0.113 | 66 | 10 | 0.152 | 0 |
KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0004860 | Not Cancer Driver | No | 107 | 0.129 | 266 | 27 | 0.102 | 0 |
LILRB4 | LILRB4 | Q8NHJ6 | Leukocyte immunoglobulin-like receptor subfamily B member 4 | chr19 | GO:0004860 | Not Cancer Driver | No | 162 | 0.362 | 277 | 115 | 0.415 | 0 |
MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0004860 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
MBIP | MBIP | Q9NS73 | MAP3K12-binding inhibitory protein 1 | chr14 | GO:0004860 | Not Cancer Driver | No | 47 | 0.137 | 190 | 20 | 0.105 | 0 |
NCAPG2_ENST00000356309 | NCAPG2 | Q86XI2 | Condensin-2 complex subunit G2 | chr7 | GO:0004860 | Not Cancer Driver | No | 113 | 0.099 | 72 | 8 | 0.111 | 3 |
NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:0004860 | Not Cancer Driver | No | 48 | 0.127 | 111 | 17 | 0.153 | 0 |
NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | GO:0004860 | Census, Compendium | Yes | 29 | 0.099 | 249 | 22 | 0.088 | 0 |
PKIA | PKIA | P61925 | cAMP-dependent protein kinase inhibitor alpha | chr8 | GO:0004860 | Not Cancer Driver | No | 18 | 0.237 | 76 | 18 | 0.237 | 0 |
PKIB_ENST00000368448 | PKIB | Q9C010 | cAMP-dependent protein kinase inhibitor beta | chr6 | GO:0004860 | Not Cancer Driver | No | 13 | 0.167 | 78 | 13 | 0.167 | 0 |
PKIG_ENST00000372891 | PKIG | Q9Y2B9 | cAMP-dependent protein kinase inhibitor gamma | chr20 | GO:0004860 | Not Cancer Driver | No | 15 | 0.197 | 76 | 15 | 0.197 | 0 |
PPP1R1B | PPP1R1B | Q9UD71 | Protein phosphatase 1 regulatory subunit 1B | chr17 | GO:0004860 | Not Cancer Driver | No | 30 | 0.147 | 204 | 30 | 0.147 | 0 |
PRKAG2 | PRKAG2 | Q9UGJ0 | 5'-AMP-activated protein kinase subunit gamma-2 | chr7 | GO:0004860 | Not Cancer Driver | No | 76 | 0.134 | 240 | 45 | 0.188 | 7 |
PRKAR1A_ENST00000536854 | PRKAR1A | P10644 | cAMP-dependent protein kinase type I-alpha regulatory subunit | chr17 | GO:0004860 | Census, Compendium | Yes | 39 | 0.102 | 66 | 11 | 0.167 | 17 |
PRKAR1B_ENST00000403562 | PRKAR1B | P31321 | cAMP-dependent protein kinase type I-beta regulatory subunit | chr7 | GO:0004860 | Not Cancer Driver | No | 53 | 0.139 | 71 | 13 | 0.183 | 0 |
PRKAR2A | PRKAR2A | P13861 | cAMP-dependent protein kinase type II-alpha regulatory subunit | chr3 | GO:0004860 | Not Cancer Driver | No | 37 | 0.092 | 149 | 13 | 0.087 | 0 |
PRKAR2B | PRKAR2B | P31323 | cAMP-dependent protein kinase type II-beta regulatory subunit | chr7 | GO:0004860 | Not Cancer Driver | No | 60 | 0.144 | 125 | 4 | 0.032 | 0 |
PRKRIP1_ENST00000397912 | PRKRIP1 | Q9H875 | PRKR-interacting protein 1 | chr7 | GO:0004860 | Not Cancer Driver | No | 22 | 0.12 | 184 | 22 | 0.12 | 0 |
QARS | QARS1 | P47897 | Glutamine--tRNA ligase | chr3 | GO:0004860 | Not Cancer Driver | No | 101 | 0.13 | 106 | 16 | 0.151 | 4 |
RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0004860 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0004860 | Not Cancer Driver | No | 176 | 0.132 | 241 | 21 | 0.087 | 0 |
SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0004860 | Not Cancer Driver | No | 27 | 0.109 | 75 | 9 | 0.12 | 0 |
SH3BP5 | SH3BP5 | O60239 | SH3 domain-binding protein 5 | chr3 | GO:0004860 | Not Cancer Driver | No | 46 | 0.101 | 378 | 35 | 0.093 | 0 |
SH3BP5L | SH3BP5L | Q7L8J4 | SH3 domain-binding protein 5-like | chr1 | GO:0004860 | Not Cancer Driver | No | 62 | 0.158 | 376 | 57 | 0.152 | 0 |
SMCR8 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | GO:0004860 | Not Cancer Driver | No | 107 | 0.114 | 357 | 38 | 0.106 | 0 |
SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0004860 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
SOCS1 | SOCS1 | O15524 | Suppressor of cytokine signaling 1 | chr16 | GO:0004860 | Census, Compendium | Yes | 22 | 0.104 | 66 | 3 | 0.045 | 2 |
SOCS3 | SOCS3 | O14543 | Suppressor of cytokine signaling 3 | chr17 | GO:0004860 | Not Cancer Driver | No | 27 | 0.12 | 111 | 14 | 0.126 | 0 |
SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | GO:0004860 | Not Cancer Driver | No | 71 | 0.16 | 194 | 35 | 0.18 | 2 |
SPRED2 | SPRED2 | Q7Z698 | Sprouty-related, EVH1 domain-containing protein 2 | chr2 | GO:0004860 | Not Cancer Driver | No | 73 | 0.175 | 228 | 43 | 0.189 | 0 |
SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0004860 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
SPRY4_ENST00000434127 | SPRY4 | Q9C004 | Protein sprouty homolog 4 | chr5 | GO:0004860 | Not Cancer Driver | No | 34 | 0.114 | 134 | 20 | 0.149 | 7 |
TAOK3 | TAOK3 | Q9H2K8 | Serine/threonine-protein kinase TAO3 | chr12 | GO:0004860 | Not Cancer Driver | No | 123 | 0.137 | 494 | 64 | 0.13 | 0 |
TESC | TESC | Q96BS2 | Calcineurin B homologous protein 3 | chr12 | GO:0004860 | Not Cancer Driver | No | 31 | 0.145 | 73 | 6 | 0.082 | 0 |
TRIB1 | TRIB1 | Q96RU8 | Tribbles homolog 1 | chr8 | GO:0004860 | Not Cancer Driver | No | 47 | 0.126 | 91 | 5 | 0.055 | 0 |
TRIB2 | TRIB2 | Q92519 | Tribbles homolog 2 | chr2 | GO:0004860 | Not Cancer Driver | No | 64 | 0.187 | 43 | 5 | 0.116 | 0 |
TRIB3_ENST00000217233 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0004860 | Not Cancer Driver | No | 65 | 0.182 | 114 | 24 | 0.211 | 0 |
WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | GO:0004860 | Not Cancer Driver | No | 278 | 0.117 | 1959 | 223 | 0.114 | 0 |
YWHAB_ENST00000353703 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | GO:0004860 | Not Cancer Driver | No | 22 | 0.089 | 109 | 4 | 0.037 | 0 |
YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | GO:0004860 | Not Cancer Driver | No | 26 | 0.105 | 77 | 9 | 0.117 | 2 |