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Total number of protein in "GO:0004714" GO term:  62

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0004714 Census, Compendium Yes 303 0.187 575 114 0.198 16
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0004714 Not Cancer Driver No 168 0.188 341 64 0.188 0
CRIM1 CRIM1 Q9NZV1 Cysteine-rich motor neuron 1 protein chr2 GO:0004714 Not Cancer Driver No 133 0.128 35 4 0.114 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0004714 Census Yes 133 0.137 124 17 0.137 20
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 GO:0004714 Not Cancer Driver No 123 0.135 253 49 0.194 0
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0004714 Census Yes 192 0.225 118 34 0.288 7
EFEMP1_ENST00000355426 EFEMP1 Q12805 EGF-containing fibulin-like extracellular matrix protein 1 chr2 GO:0004714 Not Cancer Driver No 95 0.193 73 21 0.288 1
EFNA3 EFNA3 P52797 Ephrin-A3 chr1 GO:0004714 Not Cancer Driver No 24 0.101 31 11 0.355 0
EFNA4_ENST00000368409 EFNA4 P52798 Ephrin-A4 chr1 GO:0004714 Not Cancer Driver No 28 0.139 17 3 0.176 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0004714 Not Cancer Driver No 45 0.132 183 22 0.12 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0004714 Census, Compendium Yes 444 0.367 223 35 0.157 1
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0004714 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA10 EPHA10 Q5JZY3 Ephrin type-A receptor 10 chr1 GO:0004714 Not Cancer Driver No 171 0.17 225 41 0.182 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0004714 Compendium Yes 171 0.175 187 39 0.209 3
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0004714 Census, Compendium Yes 346 0.352 74 28 0.378 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0004714 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 GO:0004714 Not Cancer Driver No 341 0.329 83 39 0.47 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0004714 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0004714 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0004714 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0004714 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0004714 Not Cancer Driver No 155 0.155 137 16 0.117 0
EPHB4 EPHB4 P54760 Ephrin type-B receptor 4 chr7 GO:0004714 Not Cancer Driver No 125 0.127 184 19 0.103 11
EPHB6_ENST00000422643 EPHB6 O15197 Ephrin type-B receptor 6 chr7 GO:0004714 Not Cancer Driver No 227 0.222 246 45 0.183 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0004714 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0004714 Census, Compendium Yes 428 0.327 323 116 0.359 2
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0004714 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0004714 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0004714 Census, Compendium Yes 173 0.215 241 26 0.108 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0004714 Census, Compendium Yes 113 0.141 162 28 0.173 0
FGFRL1_ENST00000264748 FGFRL1 Q8N441 Fibroblast growth factor receptor-like 1 chr4 GO:0004714 Not Cancer Driver No 74 0.147 278 34 0.122 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0004714 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0004714 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0004714 Census, Compendium Yes 253 0.186 259 41 0.158 13
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0004714 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 GO:0004714 Not Cancer Driver No 318 0.128 255 20 0.078 0
INSR INSR P06213 Insulin receptor chr19 GO:0004714 Not Cancer Driver No 190 0.137 280 57 0.204 64
INSRR INSRR P14616 Insulin receptor-related protein chr1 GO:0004714 Not Cancer Driver No 262 0.202 228 37 0.162 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0004714 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0004714 Census, Compendium Yes 226 0.232 83 33 0.398 21
LMTK2 LMTK2 Q8IWU2 Serine/threonine-protein kinase LMTK2 chr7 GO:0004714 Not Cancer Driver No 211 0.14 1018 141 0.139 0
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0004714 Not Cancer Driver No 103 0.119 301 30 0.1 0
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0004714 Not Cancer Driver No 175 0.175 159 31 0.195 3
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0004714 Census, Compendium Yes 226 0.163 62 15 0.242 19
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 GO:0004714 Not Cancer Driver No 178 0.127 182 27 0.148 1
MUSK MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0004714 Not Cancer Driver No 188 0.216 35 7 0.2 7
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0004714 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0004714 Not Cancer Driver No 161 0.173 207 45 0.217 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0004714 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0004714 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0004714 Census, Compendium Yes 249 0.297 57 21 0.368 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0004714 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0004714 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDGFRL PDGFRL Q15198 Platelet-derived growth factor receptor-like protein chr8 GO:0004714 Not Cancer Driver No 46 0.123 67 12 0.179 1
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0004714 Census, Compendium Yes 208 0.187 105 12 0.114 139
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 GO:0004714 Not Cancer Driver No 144 0.154 280 43 0.154 1
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0004714 Not Cancer Driver No 203 0.215 299 71 0.237 5
ROS1 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 GO:0004714 Census Yes 498 0.212 191 55 0.288 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0004714 Not Cancer Driver No 55 0.091 85 4 0.047 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0004714 Not Cancer Driver No 219 0.195 126 22 0.175 10
TIE1 TIE1 P35590 Tyrosine-protein kinase receptor Tie-1 chr1 GO:0004714 Not Cancer Driver No 200 0.176 223 46 0.206 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0004714 Not Cancer Driver No 119 0.134 197 17 0.086 0