Total number of protein in "GO:0004553" GO term: 87
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABHD10 | ABHD10 | Q9NUJ1 | Palmitoyl-protein thioesterase ABHD10, mitochondrial | chr3 | GO:0004553 | Not Cancer Driver | No | 38 | 0.124 | 7 | 2 | 0.286 | 0 |
| AC010422.5 | AC010422.5 | M0R2P5 | PAT complex subunit Asterix (Fragment) | chr19 | GO:0004553 | Not Cancer Driver | No | 26 | 0.133 | 29 | 3 | 0.103 | 0 |
| ACER1 | ACER1 | Q8TDN7 | Alkaline ceramidase 1 | chr19 | GO:0004553 | Not Cancer Driver | No | 54 | 0.205 | 0 | 0 | 0.0 | 0 |
| ACER2 | ACER2 | Q5QJU3 | Alkaline ceramidase 2 | chr9 | GO:0004553 | Not Cancer Driver | No | 27 | 0.098 | 0 | 0 | 0.0 | 0 |
| ACER3 | ACER3 | Q9NUN7 | Alkaline ceramidase 3 | chr11 | GO:0004553 | Not Cancer Driver | No | 28 | 0.105 | 0 | 0 | 0.0 | 1 |
| ADPRHL2 | ADPRS | Q9NX46 | ADP-ribosylhydrolase ARH3 | chr1 | GO:0004553 | Not Cancer Driver | No | 32 | 0.088 | 49 | 4 | 0.082 | 1 |
| AGL_ENST00000361915 | AGL | P35573 | Glycogen debranching enzyme | chr1 | GO:0004553 | Not Cancer Driver | No | 182 | 0.119 | 143 | 23 | 0.161 | 1 |
| AMY1A | AMY1A | P0DUB6 | Alpha-amylase 1A | chr1 | GO:0004553 | Not Cancer Driver | No | 20 | 0.039 | 29 | 0 | 0.0 | 0 |
| AMY1B_ENST00000370080 | AMY1B | P0DTE7 | Alpha-amylase 1B | chr1 | GO:0004553 | Not Cancer Driver | No | 14 | 0.027 | 29 | 0 | 0.0 | 0 |
| AMY1C | AMY1C | P0DTE8 | Alpha-amylase 1C | chr1 | GO:0004553 | Not Cancer Driver | No | 37 | 0.072 | 29 | 2 | 0.069 | 0 |
| AMY2A | AMY2A | P04746 | Pancreatic alpha-amylase | chr1 | GO:0004553 | Not Cancer Driver | No | 102 | 0.2 | 30 | 1 | 0.033 | 0 |
| AMY2B | AMY2B | P19961 | Alpha-amylase 2B | chr1 | GO:0004553 | Not Cancer Driver | No | 140 | 0.274 | 32 | 11 | 0.344 | 0 |
| CEMIP2 | CEMIP2 | Q9UHN6 | Cell surface hyaluronidase | chr9 | GO:0004553 | Not Cancer Driver | No | 198 | 0.143 | 229 | 26 | 0.114 | 0 |
| CEMIP_ENST00000356249 | CEMIP | Q8WUJ3 | Cell migration-inducing and hyaluronan-binding protein | chr15 | GO:0004553 | Not Cancer Driver | No | 207 | 0.152 | 105 | 10 | 0.095 | 0 |
| CHIT1 | CHIT1 | Q13231 | Chitotriosidase-1 | chr1 | GO:0004553 | Not Cancer Driver | No | 86 | 0.185 | 85 | 11 | 0.129 | 0 |
| EDEM1 | EDEM1 | Q92611 | ER degradation-enhancing alpha-mannosidase-like protein 1 | chr3 | GO:0004553 | Not Cancer Driver | No | 54 | 0.082 | 141 | 5 | 0.035 | 0 |
| EDEM2 | EDEM2 | Q9BV94 | ER degradation-enhancing alpha-mannosidase-like protein 2 | chr20 | GO:0004553 | Not Cancer Driver | No | 69 | 0.119 | 54 | 3 | 0.056 | 0 |
| EDEM3 | EDEM3 | Q9BZQ6 | ER degradation-enhancing alpha-mannosidase-like protein 3 | chr1 | GO:0004553 | Not Cancer Driver | No | 108 | 0.116 | 298 | 38 | 0.128 | 0 |
| ENGASE | ENGASE | Q8NFI3 | Cytosolic endo-beta-N-acetylglucosaminidase | chr17 | GO:0004553 | Not Cancer Driver | No | 93 | 0.125 | 87 | 8 | 0.092 | 0 |
| FUCA1 | FUCA1 | P04066 | Tissue alpha-L-fucosidase | chr1 | GO:0004553 | Not Cancer Driver | No | 42 | 0.09 | 11 | 1 | 0.091 | 3 |
| FUCA2 | FUCA2 | Q9BTY2 | Plasma alpha-L-fucosidase | chr6 | GO:0004553 | Not Cancer Driver | No | 50 | 0.107 | 2 | 0 | 0.0 | 0 |
| GAA_ENST00000390015 | GAA | P10253 | Lysosomal alpha-glucosidase | chr17 | GO:0004553 | Not Cancer Driver | No | 101 | 0.106 | 147 | 18 | 0.122 | 131 |
| GALC | GALC | P54803 | Galactocerebrosidase | chr14 | GO:0004553 | Not Cancer Driver | No | 88 | 0.128 | 21 | 2 | 0.095 | 44 |
| GANAB_ENST00000356638 | GANAB | Q14697 | Neutral alpha-glucosidase AB | chr11 | GO:0004553 | Not Cancer Driver | No | 129 | 0.137 | 132 | 20 | 0.152 | 3 |
| GANC | GANC | Q8TET4 | Neutral alpha-glucosidase C | chr15 | GO:0004553 | Not Cancer Driver | No | 104 | 0.114 | 61 | 3 | 0.049 | 0 |
| GBA2 | GBA2 | Q9HCG7 | Non-lysosomal glucosylceramidase | chr9 | GO:0004553 | Not Cancer Driver | No | 96 | 0.104 | 157 | 12 | 0.076 | 3 |
| GBA3 | GBA3 | Q9H227 | Cytosolic beta-glucosidase | chr4 | GO:0004553 | Not Cancer Driver | No | 118 | 0.252 | 18 | 6 | 0.333 | 0 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0004553 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| GBE1 | GBE1 | Q04446 | 1,4-alpha-glucan-branching enzyme | chr3 | GO:0004553 | Not Cancer Driver | No | 101 | 0.144 | 8 | 0 | 0.0 | 9 |
| GLA | GLA | P06280 | Alpha-galactosidase A | chrX | GO:0004553 | Not Cancer Driver | No | 71 | 0.166 | 7 | 2 | 0.286 | 180 |
| GLB1 | GLB1 | P16278 | Beta-galactosidase | chr3 | GO:0004553 | Not Cancer Driver | No | 72 | 0.106 | 54 | 6 | 0.111 | 99 |
| GLB1L | GLB1L | Q6UWU2 | Beta-galactosidase-1-like protein | chr2 | GO:0004553 | Not Cancer Driver | No | 71 | 0.109 | 11 | 2 | 0.182 | 0 |
| GLB1L2_ENST00000339772 | GLB1L2 | Q8IW92 | Beta-galactosidase-1-like protein 2 | chr11 | GO:0004553 | Not Cancer Driver | No | 103 | 0.162 | 8 | 1 | 0.125 | 0 |
| GLB1L3 | GLB1L3 | Q8NCI6 | Beta-galactosidase-1-like protein 3 | chr11 | GO:0004553 | Not Cancer Driver | No | 119 | 0.182 | 32 | 2 | 0.062 | 0 |
| GM2A | GM2A | P17900 | Ganglioside GM2 activator | chr5 | GO:0004553 | Not Cancer Driver | No | 26 | 0.135 | 0 | 0 | 0.0 | 2 |
| GNE_ENST00000539815 | GNE | Q9Y223 | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase | chr9 | GO:0004553 | Not Cancer Driver | No | 83 | 0.115 | 15 | 2 | 0.133 | 36 |
| GUSB | GUSB | P08236 | Beta-glucuronidase | chr7 | GO:0004553 | Not Cancer Driver | No | 93 | 0.143 | 11 | 0 | 0.0 | 36 |
| HEXA_ENST00000268097 | HEXA | P06865 | Beta-hexosaminidase subunit alpha | chr15 | GO:0004553 | Not Cancer Driver | No | 59 | 0.112 | 5 | 1 | 0.2 | 49 |
| HEXB | HEXB | P07686 | Beta-hexosaminidase subunit beta | chr5 | GO:0004553 | Not Cancer Driver | No | 45 | 0.081 | 0 | 0 | 0.0 | 9 |
| HEXD_ENST00000327949 | HEXD | Q8WVB3 | Hexosaminidase D | chr17 | GO:0004553 | Not Cancer Driver | No | 60 | 0.123 | 40 | 0 | 0.0 | 0 |
| HPSE | HPSE | Q9Y251 | Heparanase | chr4 | GO:0004553 | Not Cancer Driver | No | 90 | 0.166 | 16 | 2 | 0.125 | 0 |
| HPSE2 | HPSE2 | Q8WWQ2 | Inactive heparanase-2 | chr10 | GO:0004553 | Not Cancer Driver | No | 123 | 0.208 | 42 | 20 | 0.476 | 0 |
| HYAL1_ENST00000395144 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:0004553 | Not Cancer Driver | No | 47 | 0.108 | 9 | 0 | 0.0 | 1 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0004553 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| HYAL3 | HYAL3 | O43820 | Hyaluronidase-3 | chr3 | GO:0004553 | Not Cancer Driver | No | 48 | 0.115 | 10 | 0 | 0.0 | 0 |
| HYAL4_ENST00000476325 | HYAL4 | Q2M3T9 | Hyaluronidase-4 | chr7 | GO:0004553 | Not Cancer Driver | No | 100 | 0.208 | 0 | 0 | 0.0 | 0 |
| IDUA | IDUA | P35475 | Alpha-L-iduronidase | chr4 | GO:0004553 | Not Cancer Driver | No | 46 | 0.07 | 101 | 5 | 0.05 | 57 |
| KL | KL | Q9UEF7 | Klotho | chr13 | GO:0004553 | Not Cancer Driver | No | 175 | 0.173 | 104 | 5 | 0.048 | 1 |
| KLB | KLB | Q86Z14 | Beta-klotho | chr4 | GO:0004553 | Not Cancer Driver | No | 139 | 0.133 | 6 | 1 | 0.167 | 0 |
| LCT | LCT | P09848 | Lactase/phlorizin hydrolase | chr2 | GO:0004553 | Not Cancer Driver | No | 411 | 0.213 | 248 | 60 | 0.242 | 2 |
| LCTL | LCTL | Q6UWM7 | Lactase-like protein | chr15 | GO:0004553 | Not Cancer Driver | No | 97 | 0.171 | 17 | 5 | 0.294 | 0 |
| LYG1 | LYG1 | Q8N1E2 | Lysozyme g-like protein 1 | chr2 | GO:0004553 | Not Cancer Driver | No | 18 | 0.093 | 36 | 4 | 0.111 | 0 |
| LYG2 | LYG2 | Q86SG7 | Lysozyme g-like protein 2 | chr2 | GO:0004553 | Not Cancer Driver | No | 38 | 0.179 | 1 | 1 | 1.0 | 0 |
| LYZ | LYZ | P61626 | Lysozyme C | chr12 | GO:0004553 | Not Cancer Driver | No | 26 | 0.176 | 0 | 0 | 0.0 | 2 |
| LYZL4 | LYZL4 | Q96KX0 | Lysozyme-like protein 4 | chr3 | GO:0004553 | Not Cancer Driver | No | 25 | 0.171 | 0 | 0 | 0.0 | 0 |
| MAN1A1 | MAN1A1 | P33908 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA | chr6 | GO:0004553 | Not Cancer Driver | No | 118 | 0.181 | 134 | 23 | 0.172 | 0 |
| MAN1A2 | MAN1A2 | O60476 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB | chr1 | GO:0004553 | Not Cancer Driver | No | 74 | 0.115 | 128 | 18 | 0.141 | 0 |
| MAN1B1 | MAN1B1 | Q9UKM7 | Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase | chr9 | GO:0004553 | Not Cancer Driver | No | 74 | 0.106 | 172 | 22 | 0.128 | 2 |
| MAN1C1 | MAN1C1 | Q9NR34 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC | chr1 | GO:0004553 | Not Cancer Driver | No | 83 | 0.132 | 130 | 20 | 0.154 | 0 |
| MAN2A1 | MAN2A1 | Q16706 | Alpha-mannosidase 2 | chr5 | GO:0004553 | Not Cancer Driver | No | 165 | 0.144 | 83 | 9 | 0.108 | 0 |
| MAN2A2 | MAN2A2 | P49641 | Alpha-mannosidase 2x | chr15 | GO:0004553 | Not Cancer Driver | No | 122 | 0.106 | 53 | 6 | 0.113 | 0 |
| MAN2B1 | MAN2B1 | O00754 | Lysosomal alpha-mannosidase | chr19 | GO:0004553 | Not Cancer Driver | No | 139 | 0.137 | 145 | 21 | 0.145 | 40 |
| MAN2B2 | MAN2B2 | Q9Y2E5 | Epididymis-specific alpha-mannosidase | chr4 | GO:0004553 | Not Cancer Driver | No | 135 | 0.134 | 153 | 23 | 0.15 | 0 |
| MAN2C1_ENST00000267978 | MAN2C1 | Q9NTJ4 | Alpha-mannosidase 2C1 | chr15 | GO:0004553 | Not Cancer Driver | No | 120 | 0.115 | 72 | 4 | 0.056 | 0 |
| MANBA | MANBA | O00462 | Beta-mannosidase | chr4 | GO:0004553 | Not Cancer Driver | No | 108 | 0.123 | 10 | 0 | 0.0 | 3 |
| MANEA | MANEA | Q5SRI9 | Glycoprotein endo-alpha-1,2-mannosidase | chr6 | GO:0004553 | Not Cancer Driver | No | 91 | 0.197 | 80 | 14 | 0.175 | 0 |
| MANEAL | MANEAL | Q5VSG8 | Glycoprotein endo-alpha-1,2-mannosidase-like protein | chr1 | GO:0004553 | Not Cancer Driver | No | 34 | 0.074 | 136 | 9 | 0.066 | 0 |
| MGAM2 | MGAM2 | Q2M2H8 | Probable maltase-glucoamylase 2 | chr7 | GO:0004553 | Not Cancer Driver | No | 62 | 0.025 | 723 | 6 | 0.008 | 0 |
| MGAM_ENST00000475668 | MGAM | O43451 | Maltase-glucoamylase | chr7 | GO:0004553 | Not Cancer Driver | No | 708 | 0.257 | 315 | 94 | 0.298 | 0 |
| MOGS | MOGS | Q13724 | Mannosyl-oligosaccharide glucosidase | chr2 | GO:0004553 | Not Cancer Driver | No | 105 | 0.125 | 200 | 29 | 0.145 | 2 |
| MYORG | MYORG | Q6NSJ0 | Myogenesis-regulating glycosidase | chr9 | GO:0004553 | Not Cancer Driver | No | 88 | 0.123 | 60 | 3 | 0.05 | 2 |
| NAGA | NAGA | P17050 | Alpha-N-acetylgalactosaminidase | chr22 | GO:0004553 | Not Cancer Driver | No | 47 | 0.114 | 2 | 0 | 0.0 | 4 |
| NAGLU | NAGLU | P54802 | Alpha-N-acetylglucosaminidase | chr17 | GO:0004553 | Not Cancer Driver | No | 70 | 0.094 | 18 | 1 | 0.056 | 68 |
| NAGPA | NAGPA | Q9UK23 | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase | chr16 | GO:0004553 | Not Cancer Driver | No | 47 | 0.091 | 131 | 11 | 0.084 | 0 |
| NEU1 | NEU1 | Q99519 | Sialidase-1 | chr6 | GO:0004553 | Not Cancer Driver | No | 52 | 0.125 | 65 | 6 | 0.092 | 23 |
| NEU2 | NEU2 | Q9Y3R4 | Sialidase-2 | chr2 | GO:0004553 | Not Cancer Driver | No | 88 | 0.232 | 144 | 32 | 0.222 | 0 |
| NEU4_ENST00000407683 | NEU4 | Q8WWR8 | Sialidase-4 | chr2 | GO:0004553 | Not Cancer Driver | No | 82 | 0.169 | 199 | 37 | 0.186 | 0 |
| OGA | OGA | O60502 | Protein O-GlcNAcase | chr10 | GO:0004553 | Not Cancer Driver | No | 89 | 0.097 | 241 | 15 | 0.062 | 0 |
| OTOG | OTOG | Q6ZRI0 | Otogelin | chr11 | GO:0004553 | Not Cancer Driver | No | 62 | 0.021 | 728 | 27 | 0.037 | 1 |
| OTOGL | OTOGL | Q3ZCN5 | Otogelin-like protein | chr12 | GO:0004553 | Not Cancer Driver | No | 473 | 0.201 | 0 | 0 | 0.0 | 0 |
| PARG_ENST00000616448 | PARG | Q86W56 | Poly(ADP-ribose) glycohydrolase | chr10 | GO:0004553 | Not Cancer Driver | No | 60 | 0.061 | 519 | 1 | 0.002 | 0 |
| PGGHG | PGGHG | Q32M88 | Protein-glucosylgalactosylhydroxylysine glucosidase | chr11 | GO:0004553 | Not Cancer Driver | No | 77 | 0.104 | 168 | 16 | 0.095 | 0 |
| SI | SI | P14410 | Sucrase-isomaltase, intestinal | chr3 | GO:0004553 | Not Cancer Driver | No | 691 | 0.378 | 144 | 66 | 0.458 | 11 |
| SPACA3 | SPACA3 | Q8IXA5 | Sperm acrosome membrane-associated protein 3 | chr17 | GO:0004553 | Not Cancer Driver | No | 52 | 0.242 | 0 | 0 | 0.0 | 0 |
| SPACA5_ENST00000376940 | SPACA5B | Q96QH8 | Sperm acrosome-associated protein 5 | chrX | GO:0004553 | Not Cancer Driver | No | 6 | 0.038 | 0 | 0 | 0.0 | 0 |
| SPAM1_ENST00000439500 | SPAM1 | P38567 | Hyaluronidase PH-20 | chr7 | GO:0004553 | Not Cancer Driver | No | 172 | 0.338 | 5 | 1 | 0.2 | 0 |
| TREH | TREH | O43280 | Trehalase | chr11 | GO:0004553 | Not Cancer Driver | No | 47 | 0.081 | 34 | 3 | 0.088 | 0 |