Total number of protein in "GO:0004540" GO term: 85
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | GO:0004540 | Not Cancer Driver | No | 126 | 0.147 | 141 | 15 | 0.106 | 11 |
| AGO3 | AGO3 | Q9H9G7 | Protein argonaute-3 | chr1 | GO:0004540 | Not Cancer Driver | No | 110 | 0.128 | 143 | 19 | 0.133 | 0 |
| ANG | ANG | P03950 | Angiogenin | chr14 | GO:0004540 | Not Cancer Driver | No | 19 | 0.129 | 36 | 2 | 0.056 | 14 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0004540 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
| AZGP1 | AZGP1 | P25311 | Zinc-alpha-2-glycoprotein | chr7 | GO:0004540 | Not Cancer Driver | No | 59 | 0.198 | 41 | 10 | 0.244 | 0 |
| CNOT1 | CNOT1 | A5YKK6 | CCR4-NOT transcription complex subunit 1 | chr16 | GO:0004540 | Not Cancer Driver | No | 346 | 0.146 | 464 | 56 | 0.121 | 12 |
| CNOT2 | CNOT2 | Q9NZN8 | CCR4-NOT transcription complex subunit 2 | chr12 | GO:0004540 | Not Cancer Driver | No | 84 | 0.156 | 354 | 66 | 0.186 | 0 |
| CNOT6L | CNOT6L | Q96LI5 | CCR4-NOT transcription complex subunit 6-like | chr4 | GO:0004540 | Not Cancer Driver | No | 58 | 0.105 | 37 | 3 | 0.081 | 0 |
| CNOT6_ENST00000261951 | CNOT6 | Q9ULM6 | CCR4-NOT transcription complex subunit 6 | chr5 | GO:0004540 | Not Cancer Driver | No | 65 | 0.117 | 66 | 4 | 0.061 | 0 |
| CNOT7 | CNOT7 | Q9UIV1 | CCR4-NOT transcription complex subunit 7 | chr8 | GO:0004540 | Not Cancer Driver | No | 31 | 0.109 | 21 | 1 | 0.048 | 0 |
| CNOT8 | CNOT8 | Q9UFF9 | CCR4-NOT transcription complex subunit 8 | chr5 | GO:0004540 | Not Cancer Driver | No | 30 | 0.103 | 6 | 0 | 0.0 | 0 |
| CPSF3 | CPSF3 | Q9UKF6 | Cleavage and polyadenylation specificity factor subunit 3 | chr2 | GO:0004540 | Not Cancer Driver | No | 78 | 0.114 | 56 | 9 | 0.161 | 0 |
| DBR1 | DBR1 | Q9UK59 | Lariat debranching enzyme | chr3 | GO:0004540 | Not Cancer Driver | No | 58 | 0.107 | 185 | 28 | 0.151 | 3 |
| DCP2 | DCP2 | Q8IU60 | m7GpppN-mRNA hydrolase | chr5 | GO:0004540 | Not Cancer Driver | No | 57 | 0.136 | 167 | 24 | 0.144 | 0 |
| DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | GO:0004540 | Not Cancer Driver | No | 48 | 0.142 | 53 | 6 | 0.113 | 1 |
| DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | GO:0004540 | Census, Compendium | Yes | 264 | 0.137 | 362 | 45 | 0.124 | 4 |
| DIS3L2 | DIS3L2 | Q8IYB7 | DIS3-like exonuclease 2 | chr2 | GO:0004540 | Not Cancer Driver | No | 114 | 0.129 | 264 | 22 | 0.083 | 1 |
| DROSHA_ENST00000344624 | DROSHA | Q9NRR4 | Ribonuclease 3 | chr5 | GO:0004540 | Census, Compendium | Yes | 175 | 0.127 | 682 | 100 | 0.147 | 0 |
| EDC3 | EDC3 | Q96F86 | Enhancer of mRNA-decapping protein 3 | chr15 | GO:0004540 | Not Cancer Driver | No | 43 | 0.085 | 185 | 22 | 0.119 | 1 |
| ELAC1 | ELAC1 | Q9H777 | Zinc phosphodiesterase ELAC protein 1 | chr18 | GO:0004540 | Not Cancer Driver | No | 40 | 0.11 | 47 | 4 | 0.085 | 0 |
| ELAC2 | ELAC2 | Q9BQ52 | Zinc phosphodiesterase ELAC protein 2 | chr17 | GO:0004540 | Not Cancer Driver | No | 86 | 0.104 | 208 | 30 | 0.144 | 10 |
| ENDOV | ENDOV | Q8N8Q3 | Endonuclease V | chr17 | GO:0004540 | Not Cancer Driver | No | 28 | 0.099 | 43 | 3 | 0.07 | 0 |
| EXO1_ENST00000348581 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0004540 | Not Cancer Driver | No | 123 | 0.145 | 472 | 76 | 0.161 | 0 |
| EXOSC1 | EXOSC1 | Q9Y3B2 | Exosome complex component CSL4 | chr10 | GO:0004540 | Not Cancer Driver | No | 14 | 0.072 | 14 | 2 | 0.143 | 1 |
| EXOSC10 | EXOSC10 | Q01780 | Exosome component 10 | chr1 | GO:0004540 | Not Cancer Driver | No | 87 | 0.098 | 375 | 35 | 0.093 | 0 |
| EXOSC2 | EXOSC2 | Q13868 | Exosome complex component RRP4 | chr9 | GO:0004540 | Not Cancer Driver | No | 21 | 0.072 | 47 | 6 | 0.128 | 2 |
| EXOSC3 | EXOSC3 | Q9NQT5 | Exosome complex component RRP40 | chr9 | GO:0004540 | Not Cancer Driver | No | 18 | 0.065 | 54 | 2 | 0.037 | 4 |
| EXOSC4 | EXOSC4 | Q9NPD3 | Exosome complex component RRP41 | chr8 | GO:0004540 | Not Cancer Driver | No | 34 | 0.139 | 23 | 0 | 0.0 | 0 |
| EXOSC5 | EXOSC5 | Q9NQT4 | Exosome complex component RRP46 | chr19 | GO:0004540 | Not Cancer Driver | No | 43 | 0.183 | 31 | 3 | 0.097 | 0 |
| EXOSC6 | EXOSC6 | Q5RKV6 | Exosome complex component MTR3 | chr16 | GO:0004540 | Not Cancer Driver | No | 3 | 0.011 | 102 | 0 | 0.0 | 0 |
| EXOSC7 | EXOSC7 | Q15024 | Exosome complex component RRP42 | chr3 | GO:0004540 | Not Cancer Driver | No | 41 | 0.141 | 8 | 1 | 0.125 | 0 |
| EXOSC8 | EXOSC8 | Q96B26 | Exosome complex component RRP43 | chr13 | GO:0004540 | Not Cancer Driver | No | 20 | 0.072 | 28 | 1 | 0.036 | 2 |
| EXOSC9_ENST00000243498 | EXOSC9 | Q06265 | Exosome complex component RRP45 | chr4 | GO:0004540 | Not Cancer Driver | No | 58 | 0.132 | 154 | 18 | 0.117 | 1 |
| FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0004540 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
| HELZ2 | HELZ2 | Q9BYK8 | Helicase with zinc finger domain 2 | chr20 | GO:0004540 | Not Cancer Driver | No | 320 | 0.121 | 594 | 84 | 0.141 | 0 |
| ISG20 | ISG20 | Q96AZ6 | Interferon-stimulated gene 20 kDa protein | chr15 | GO:0004540 | Not Cancer Driver | No | 20 | 0.11 | 6 | 0 | 0.0 | 0 |
| KIAA0391 | PRORP | O15091 | Mitochondrial ribonuclease P catalytic subunit | chr14 | GO:0004540 | Not Cancer Driver | No | 62 | 0.106 | 60 | 12 | 0.2 | 0 |
| MRPL44 | MRPL44 | Q9H9J2 | 39S ribosomal protein L44, mitochondrial | chr2 | GO:0004540 | Not Cancer Driver | No | 37 | 0.111 | 45 | 2 | 0.044 | 1 |
| N4BP1 | N4BP1 | O75113 | NEDD4-binding protein 1 | chr16 | GO:0004540 | Not Cancer Driver | No | 108 | 0.121 | 432 | 58 | 0.134 | 0 |
| NOCT | NOCT | Q9UK39 | Nocturnin | chr4 | GO:0004540 | Not Cancer Driver | No | 33 | 0.077 | 89 | 3 | 0.034 | 0 |
| NUDT12 | NUDT12 | Q9BQG2 | NAD-capped RNA hydrolase NUDT12 | chr5 | GO:0004540 | Not Cancer Driver | No | 65 | 0.141 | 11 | 2 | 0.182 | 0 |
| NUDT16L1 | NUDT16L1 | Q9BRJ7 | Tudor-interacting repair regulator protein | chr16 | GO:0004540 | Not Cancer Driver | No | 16 | 0.076 | 6 | 0 | 0.0 | 0 |
| NUDT16_ENST00000521288 | NUDT16 | Q96DE0 | U8 snoRNA-decapping enzyme | chr3 | GO:0004540 | Not Cancer Driver | No | 29 | 0.149 | 8 | 1 | 0.125 | 0 |
| PAN2_ENST00000548043 | PAN2 | Q504Q3 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | chr12 | GO:0004540 | Not Cancer Driver | No | 139 | 0.116 | 78 | 10 | 0.128 | 0 |
| PAN3 | PAN3 | Q58A45 | PAN2-PAN3 deadenylation complex subunit PAN3 | chr13 | GO:0004540 | Not Cancer Driver | No | 104 | 0.117 | 323 | 35 | 0.108 | 0 |
| PARN | PARN | O95453 | Poly(A)-specific ribonuclease PARN | chr16 | GO:0004540 | Not Cancer Driver | No | 71 | 0.111 | 197 | 22 | 0.112 | 2 |
| PDE12 | PDE12 | Q6L8Q7 | 2',5'-phosphodiesterase 12 | chr3 | GO:0004540 | Not Cancer Driver | No | 59 | 0.097 | 129 | 8 | 0.062 | 0 |
| PLD6 | PLD6 | Q8N2A8 | Mitochondrial cardiolipin hydrolase | chr17 | GO:0004540 | Not Cancer Driver | No | 27 | 0.107 | 24 | 6 | 0.25 | 0 |
| PNLDC1_ENST00000610273 | PNLDC1 | Q8NA58 | Poly(A)-specific ribonuclease PNLDC1 | chr6 | GO:0004540 | Not Cancer Driver | No | 105 | 0.202 | 6 | 0 | 0.0 | 1 |
| POP1_ENST00000349693 | POP1 | Q99575 | Ribonucleases P/MRP protein subunit POP1 | chr8 | GO:0004540 | Not Cancer Driver | No | 161 | 0.157 | 495 | 75 | 0.152 | 3 |
| POP4 | POP4 | O95707 | Ribonuclease P protein subunit p29 | chr19 | GO:0004540 | Not Cancer Driver | No | 25 | 0.114 | 53 | 9 | 0.17 | 0 |
| POP5 | POP5 | Q969H6 | Ribonuclease P/MRP protein subunit POP5 | chr12 | GO:0004540 | Not Cancer Driver | No | 17 | 0.104 | 9 | 2 | 0.222 | 0 |
| POP7 | POP7 | O75817 | Ribonuclease P protein subunit p20 | chr7 | GO:0004540 | Not Cancer Driver | No | 20 | 0.143 | 59 | 13 | 0.22 | 0 |
| PPP1R8 | PPP1R8 | Q12972 | Nuclear inhibitor of protein phosphatase 1 | chr1 | GO:0004540 | Not Cancer Driver | No | 24 | 0.068 | 251 | 19 | 0.076 | 0 |
| RIDA | RIDA | P52758 | 2-iminobutanoate/2-iminopropanoate deaminase | chr8 | GO:0004540 | Not Cancer Driver | No | 20 | 0.146 | 3 | 0 | 0.0 | 0 |
| RNASE10 | RNASE10 | Q5GAN6 | Inactive ribonuclease-like protein 10 | chr14 | GO:0004540 | Not Cancer Driver | No | 48 | 0.222 | 68 | 20 | 0.294 | 0 |
| RNASE11_ENST00000620912 | RNASE11 | Q8TAA1 | Probable ribonuclease 11 | chr14 | GO:0004540 | Not Cancer Driver | No | 42 | 0.211 | 29 | 7 | 0.241 | 0 |
| RNASE12 | RNASE12 | Q5GAN4 | Probable inactive ribonuclease-like protein 12 | chr14 | GO:0004540 | Not Cancer Driver | No | 23 | 0.156 | 0 | 0 | 0.0 | 0 |
| RNASE13 | RNASE13 | Q5GAN3 | Probable inactive ribonuclease-like protein 13 | chr14 | GO:0004540 | Not Cancer Driver | No | 21 | 0.135 | 0 | 0 | 0.0 | 0 |
| RNASE1_ENST00000412779 | RNASE1 | P07998 | Ribonuclease pancreatic | chr14 | GO:0004540 | Not Cancer Driver | No | 17 | 0.109 | 49 | 11 | 0.224 | 0 |
| RNASE2 | RNASE2 | P10153 | Non-secretory ribonuclease | chr14 | GO:0004540 | Not Cancer Driver | No | 30 | 0.186 | 20 | 4 | 0.2 | 0 |
| RNASE3 | RNASE3 | P12724 | Eosinophil cationic protein | chr14 | GO:0004540 | Not Cancer Driver | No | 37 | 0.231 | 8 | 0 | 0.0 | 0 |
| RNASE4_ENST00000555597 | RNASE4 | P34096 | Ribonuclease 4 | chr14 | GO:0004540 | Not Cancer Driver | No | 24 | 0.163 | 9 | 2 | 0.222 | 0 |
| RNASE6 | RNASE6 | Q93091 | Ribonuclease K6 | chr14 | GO:0004540 | Not Cancer Driver | No | 26 | 0.173 | 0 | 0 | 0.0 | 0 |
| RNASE7 | RNASE7 | Q9H1E1 | Ribonuclease 7 | chr14 | GO:0004540 | Not Cancer Driver | No | 27 | 0.173 | 42 | 4 | 0.095 | 0 |
| RNASE8 | RNASE8 | Q8TDE3 | Ribonuclease 8 | chr14 | GO:0004540 | Not Cancer Driver | No | 18 | 0.117 | 17 | 2 | 0.118 | 0 |
| RNASE9_ENST00000553541 | RNASE9 | P60153 | Inactive ribonuclease-like protein 9 | chr14 | GO:0004540 | Not Cancer Driver | No | 41 | 0.2 | 7 | 0 | 0.0 | 0 |
| RNASEH1 | RNASEH1 | O60930 | Ribonuclease H1 | chr2 | GO:0004540 | Not Cancer Driver | No | 33 | 0.115 | 124 | 20 | 0.161 | 2 |
| RNASEH2A | RNASEH2A | O75792 | Ribonuclease H2 subunit A | chr19 | GO:0004540 | Not Cancer Driver | No | 42 | 0.14 | 31 | 3 | 0.097 | 7 |
| RNASEL | RNASEL | Q05823 | 2-5A-dependent ribonuclease | chr1 | GO:0004540 | Not Cancer Driver | No | 95 | 0.128 | 147 | 17 | 0.116 | 0 |
| RNASET2_ENST00000476238 | RNASET2 | O00584 | Ribonuclease T2 | chr6 | GO:0004540 | Not Cancer Driver | No | 32 | 0.125 | 37 | 3 | 0.081 | 1 |
| RPP14_ENST00000295959 | RPP14 | O95059 | Ribonuclease P protein subunit p14 | chr3 | GO:0004540 | Not Cancer Driver | No | 8 | 0.065 | 0 | 0 | 0.0 | 0 |
| RPP21_ENST00000442966 | RPP21 | Q9H633 | Ribonuclease P protein subunit p21 | chr6 | GO:0004540 | Not Cancer Driver | No | 16 | 0.104 | 51 | 4 | 0.078 | 0 |
| RPP25 | RPP25 | Q9BUL9 | Ribonuclease P protein subunit p25 | chr15 | GO:0004540 | Not Cancer Driver | No | 11 | 0.055 | 162 | 11 | 0.068 | 0 |
| RPP30_ENST00000371703 | RPP30 | P78346 | Ribonuclease P protein subunit p30 | chr10 | GO:0004540 | Not Cancer Driver | No | 28 | 0.104 | 21 | 2 | 0.095 | 0 |
| RPP38_ENST00000378202 | RPP38 | P78345 | Ribonuclease P protein subunit p38 | chr10 | GO:0004540 | Not Cancer Driver | No | 36 | 0.127 | 118 | 19 | 0.161 | 0 |
| RPP40 | RPP40 | O75818 | Ribonuclease P protein subunit p40 | chr6 | GO:0004540 | Not Cancer Driver | No | 51 | 0.14 | 5 | 0 | 0.0 | 0 |
| SAMHD1 | SAMHD1 | Q9Y3Z3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | chr20 | GO:0004540 | Not Cancer Driver | No | 104 | 0.166 | 91 | 14 | 0.154 | 13 |
| TOE1 | TOE1 | Q96GM8 | Target of EGR1 protein 1 | chr1 | GO:0004540 | Not Cancer Driver | No | 44 | 0.086 | 210 | 22 | 0.105 | 10 |
| TSEN2 | TSEN2 | Q8NCE0 | tRNA-splicing endonuclease subunit Sen2 | chr3 | GO:0004540 | Not Cancer Driver | No | 54 | 0.116 | 153 | 17 | 0.111 | 1 |
| TSEN34_ENST00000396383 | TSEN34 | Q9BSV6 | tRNA-splicing endonuclease subunit Sen34 | chr19 | GO:0004540 | Not Cancer Driver | No | 40 | 0.129 | 176 | 22 | 0.125 | 1 |
| USB1 | USB1 | Q9BQ65 | U6 snRNA phosphodiesterase 1 | chr16 | GO:0004540 | Not Cancer Driver | No | 28 | 0.106 | 76 | 5 | 0.066 | 0 |
| XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | GO:0004540 | Not Cancer Driver | No | 213 | 0.125 | 577 | 65 | 0.113 | 0 |
| XRN2 | XRN2 | Q9H0D6 | 5'-3' exoribonuclease 2 | chr20 | GO:0004540 | Not Cancer Driver | No | 129 | 0.136 | 427 | 63 | 0.148 | 0 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0004540 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |