Total number of protein in "GO:0004529" GO term: 20
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0004529 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
| APEX2 | APEX2 | Q9UBZ4 | DNA-(apurinic or apyrimidinic site) endonuclease 2 | chrX | GO:0004529 | Not Cancer Driver | No | 66 | 0.127 | 148 | 14 | 0.095 | 0 |
| APTX_ENST00000379819 | APTX | Q7Z2E3 | Aprataxin | chr9 | GO:0004529 | Not Cancer Driver | No | 36 | 0.101 | 101 | 6 | 0.059 | 9 |
| DCLRE1A | DCLRE1A | Q6PJP8 | DNA cross-link repair 1A protein | chr10 | GO:0004529 | Not Cancer Driver | No | 92 | 0.088 | 514 | 45 | 0.088 | 0 |
| DCLRE1B | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0004529 | Not Cancer Driver | No | 65 | 0.122 | 127 | 17 | 0.134 | 0 |
| DCLRE1C | DCLRE1C | Q96SD1 | Protein artemis | chr10 | GO:0004529 | Not Cancer Driver | No | 76 | 0.11 | 277 | 26 | 0.094 | 3 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | GO:0004529 | Not Cancer Driver | No | 58 | 0.093 | 176 | 15 | 0.085 | 0 |
| EXO1_ENST00000348581 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0004529 | Not Cancer Driver | No | 123 | 0.145 | 472 | 76 | 0.161 | 0 |
| EXO5_ENST00000358527 | EXO5 | Q9H790 | Exonuclease V | chr1 | GO:0004529 | Not Cancer Driver | No | 39 | 0.105 | 36 | 3 | 0.083 | 0 |
| FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0004529 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
| ISG20 | ISG20 | Q96AZ6 | Interferon-stimulated gene 20 kDa protein | chr15 | GO:0004529 | Not Cancer Driver | No | 20 | 0.11 | 6 | 0 | 0.0 | 0 |
| MEIOB_ENST00000397344 | MEIOB | Q8N635 | Meiosis-specific with OB domain-containing protein | chr16 | GO:0004529 | Not Cancer Driver | No | 37 | 0.084 | 21 | 2 | 0.095 | 1 |
| MGME1 | MGME1 | Q9BQP7 | Mitochondrial genome maintenance exonuclease 1 | chr20 | GO:0004529 | Not Cancer Driver | No | 33 | 0.096 | 95 | 7 | 0.074 | 1 |
| PLD3_ENST00000409735 | PLD3 | Q8IV08 | 5'-3' exonuclease PLD3 | chr19 | GO:0004529 | Not Cancer Driver | No | 70 | 0.143 | 62 | 7 | 0.113 | 0 |
| PLD4_ENST00000392593 | PLD4 | Q96BZ4 | 5'-3' exonuclease PLD4 | chr14 | GO:0004529 | Not Cancer Driver | No | 46 | 0.091 | 76 | 10 | 0.132 | 0 |
| POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | GO:0004529 | Census, Compendium | Yes | 409 | 0.179 | 239 | 44 | 0.184 | 3 |
| RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0004529 | Not Cancer Driver | No | 29 | 0.103 | 4 | 1 | 0.25 | 0 |
| RAD9A | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:0004529 | Not Cancer Driver | No | 34 | 0.087 | 135 | 7 | 0.052 | 0 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0004529 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TREX2_ENST00000370231 | TREX2 | Q9BQ50 | Three prime repair exonuclease 2 | chrX | GO:0004529 | Not Cancer Driver | No | 33 | 0.14 | 23 | 6 | 0.261 | 0 |