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Total number of protein in "GO:0004521" GO term:  67

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 GO:0004521 Not Cancer Driver No 126 0.147 87 11 0.126 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0004521 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 GO:0004521 Not Cancer Driver No 110 0.128 143 19 0.133 0
ANG ANG P03950 Angiogenin chr14 GO:0004521 Not Cancer Driver No 19 0.129 36 2 0.056 14
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0004521 Not Cancer Driver No 34 0.107 103 14 0.136 0
CPSF3 CPSF3 Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 chr2 GO:0004521 Not Cancer Driver No 78 0.114 56 9 0.161 0
DBR1 DBR1 Q9UK59 Lariat debranching enzyme chr3 GO:0004521 Not Cancer Driver No 58 0.107 185 28 0.151 3
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0004521 Census, Compendium Yes 264 0.137 362 45 0.124 4
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0004521 Census, Compendium Yes 175 0.127 682 100 0.147 0
EDC3 EDC3 Q96F86 Enhancer of mRNA-decapping protein 3 chr15 GO:0004521 Not Cancer Driver No 43 0.085 185 22 0.119 1
ELAC1 ELAC1 Q9H777 Zinc phosphodiesterase ELAC protein 1 chr18 GO:0004521 Not Cancer Driver No 40 0.11 47 4 0.085 0
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 GO:0004521 Not Cancer Driver No 86 0.104 208 30 0.144 10
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0004521 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENDOU ENDOU P21128 Uridylate-specific endoribonuclease chr12 GO:0004521 Not Cancer Driver No 47 0.115 54 8 0.148 0
ENDOV ENDOV Q8N8Q3 Endonuclease V chr17 GO:0004521 Not Cancer Driver No 28 0.099 43 3 0.07 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0004521 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0004521 Not Cancer Driver No 192 0.207 213 45 0.211 0
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0004521 Not Cancer Driver No 123 0.145 472 76 0.161 0
EXOG EXOG Q9Y2C4 Nuclease EXOG, mitochondrial chr3 GO:0004521 Not Cancer Driver No 42 0.114 52 1 0.019 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0004521 Census Yes 35 0.092 111 11 0.099 0
INTS11_ENST00000435064 INTS11 Q5TA45 Integrator complex subunit 11 chr1 GO:0004521 Not Cancer Driver No 64 0.107 24 2 0.083 0
KHNYN KHNYN O15037 Protein KHNYN chr14 GO:0004521 Not Cancer Driver No 64 0.094 334 36 0.108 0
KIAA0391 PRORP O15091 Mitochondrial ribonuclease P catalytic subunit chr14 GO:0004521 Not Cancer Driver No 62 0.106 60 12 0.2 0
LACTB2 LACTB2 Q53H82 Endoribonuclease LACTB2 chr8 GO:0004521 Not Cancer Driver No 34 0.118 21 1 0.048 0
MBLAC1 MBLAC1 A4D2B0 Metallo-beta-lactamase domain-containing protein 1 chr7 GO:0004521 Not Cancer Driver No 26 0.098 175 22 0.126 0
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 GO:0004521 Not Cancer Driver No 37 0.111 45 2 0.044 1
NOB1 NOB1 Q9ULX3 RNA-binding protein NOB1 chr16 GO:0004521 Not Cancer Driver No 38 0.092 185 15 0.081 0
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0004521 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0004521 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0004521 Not Cancer Driver No 29 0.149 8 1 0.125 0
NYNRIN NYNRIN Q9P2P1 Protein NYNRIN chr14 GO:0004521 Not Cancer Driver No 250 0.132 636 70 0.11 0
PIWIL1 PIWIL1 Q96J94 Piwi-like protein 1 chr12 GO:0004521 Not Cancer Driver No 202 0.235 172 37 0.215 0
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0004521 Not Cancer Driver No 138 0.142 232 38 0.164 0
PIWIL4 PIWIL4 Q7Z3Z4 Piwi-like protein 4 chr11 GO:0004521 Not Cancer Driver No 115 0.135 89 11 0.124 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 GO:0004521 Not Cancer Driver No 27 0.107 24 6 0.25 0
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 GO:0004521 Not Cancer Driver No 161 0.157 495 75 0.152 3
POP4 POP4 O95707 Ribonuclease P protein subunit p29 chr19 GO:0004521 Not Cancer Driver No 25 0.114 53 9 0.17 0
POP5 POP5 Q969H6 Ribonuclease P/MRP protein subunit POP5 chr12 GO:0004521 Not Cancer Driver No 17 0.104 9 2 0.222 0
POP7 POP7 O75817 Ribonuclease P protein subunit p20 chr7 GO:0004521 Not Cancer Driver No 20 0.143 59 13 0.22 0
RCL1 RCL1 Q9Y2P8 RNA 3'-terminal phosphate cyclase-like protein chr9 GO:0004521 Not Cancer Driver No 40 0.107 12 0 0.0 0
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0004521 Not Cancer Driver No 20 0.146 3 0 0.0 0
RNASE1_ENST00000412779 RNASE1 P07998 Ribonuclease pancreatic chr14 GO:0004521 Not Cancer Driver No 17 0.109 49 11 0.224 0
RNASE2 RNASE2 P10153 Non-secretory ribonuclease chr14 GO:0004521 Not Cancer Driver No 30 0.186 20 4 0.2 0
RNASE4_ENST00000555597 RNASE4 P34096 Ribonuclease 4 chr14 GO:0004521 Not Cancer Driver No 24 0.163 9 2 0.222 0
RNASE8 RNASE8 Q8TDE3 Ribonuclease 8 chr14 GO:0004521 Not Cancer Driver No 18 0.117 17 2 0.118 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 GO:0004521 Not Cancer Driver No 33 0.115 124 20 0.161 2
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 GO:0004521 Not Cancer Driver No 42 0.14 31 3 0.097 7
RNASEL RNASEL Q05823 2-5A-dependent ribonuclease chr1 GO:0004521 Not Cancer Driver No 95 0.128 147 17 0.116 0
RNASET2_ENST00000476238 RNASET2 O00584 Ribonuclease T2 chr6 GO:0004521 Not Cancer Driver No 32 0.125 37 3 0.081 1
RPP14_ENST00000295959 RPP14 O95059 Ribonuclease P protein subunit p14 chr3 GO:0004521 Not Cancer Driver No 8 0.065 0 0 0.0 0
RPP21_ENST00000442966 RPP21 Q9H633 Ribonuclease P protein subunit p21 chr6 GO:0004521 Not Cancer Driver No 16 0.104 51 4 0.078 0
RPP25 RPP25 Q9BUL9 Ribonuclease P protein subunit p25 chr15 GO:0004521 Not Cancer Driver No 11 0.055 162 11 0.068 0
RPP30_ENST00000371703 RPP30 P78346 Ribonuclease P protein subunit p30 chr10 GO:0004521 Not Cancer Driver No 28 0.104 21 2 0.095 0
RPP38_ENST00000378202 RPP38 P78345 Ribonuclease P protein subunit p38 chr10 GO:0004521 Not Cancer Driver No 36 0.127 118 19 0.161 0
RPP40 RPP40 O75818 Ribonuclease P protein subunit p40 chr6 GO:0004521 Not Cancer Driver No 51 0.14 5 0 0.0 0
SLFN13 SLFN13 Q68D06 Schlafen family member 13 chr17 GO:0004521 Not Cancer Driver No 152 0.169 45 5 0.111 0
SLFN14 SLFN14 P0C7P3 Protein SLFN14 chr17 GO:0004521 Not Cancer Driver No 66 0.072 61 3 0.049 4
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:0004521 Not Cancer Driver No 166 0.117 751 97 0.129 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 GO:0004521 Census Yes 127 0.14 258 48 0.186 0
TSEN2 TSEN2 Q8NCE0 tRNA-splicing endonuclease subunit Sen2 chr3 GO:0004521 Not Cancer Driver No 54 0.116 153 17 0.111 1
TSEN34_ENST00000396383 TSEN34 Q9BSV6 tRNA-splicing endonuclease subunit Sen34 chr19 GO:0004521 Not Cancer Driver No 40 0.129 176 22 0.125 1
TSNAX TSNAX Q99598 Translin-associated protein X chr1 GO:0004521 Not Cancer Driver No 23 0.079 68 3 0.044 0
YBEY_ENST00000397691 YBEY P58557 Endoribonuclease YbeY chr21 GO:0004521 Not Cancer Driver No 19 0.114 9 2 0.222 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0004521 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H12B ZC3H12B Q5HYM0 Probable ribonuclease ZC3H12B chrX GO:0004521 Not Cancer Driver No 138 0.165 521 82 0.157 0
ZC3H12C ZC3H12C Q9C0D7 Probable ribonuclease ZC3H12C chr11 GO:0004521 Not Cancer Driver No 125 0.142 620 82 0.132 0
ZC3H12D ZC3H12D A2A288 Probable ribonuclease ZC3H12D chr6 GO:0004521 Not Cancer Driver No 48 0.091 314 18 0.057 0