Total number of protein in "GO:0004518" GO term: 125
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | GO:0004518 | Not Cancer Driver | No | 126 | 0.147 | 141 | 15 | 0.106 | 11 |
| AGO3 | AGO3 | Q9H9G7 | Protein argonaute-3 | chr1 | GO:0004518 | Not Cancer Driver | No | 110 | 0.128 | 143 | 19 | 0.133 | 0 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0004518 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
| APEX2 | APEX2 | Q9UBZ4 | DNA-(apurinic or apyrimidinic site) endonuclease 2 | chrX | GO:0004518 | Not Cancer Driver | No | 66 | 0.127 | 148 | 14 | 0.095 | 0 |
| APTX_ENST00000379819 | APTX | Q7Z2E3 | Aprataxin | chr9 | GO:0004518 | Not Cancer Driver | No | 36 | 0.101 | 101 | 6 | 0.059 | 9 |
| ASTE1_ENST00000264992 | ASTE1 | Q2TB18 | Protein asteroid homolog 1 | chr3 | GO:0004518 | Not Cancer Driver | No | 82 | 0.121 | 40 | 4 | 0.1 | 0 |
| C12orf10 | MYG1 | Q9HB07 | MYG1 exonuclease | chr12 | GO:0004518 | Not Cancer Driver | No | 30 | 0.08 | 95 | 9 | 0.095 | 0 |
| CNOT1 | CNOT1 | A5YKK6 | CCR4-NOT transcription complex subunit 1 | chr16 | GO:0004518 | Not Cancer Driver | No | 346 | 0.146 | 464 | 56 | 0.121 | 12 |
| CNOT2 | CNOT2 | Q9NZN8 | CCR4-NOT transcription complex subunit 2 | chr12 | GO:0004518 | Not Cancer Driver | No | 84 | 0.156 | 354 | 66 | 0.186 | 0 |
| CNOT6L | CNOT6L | Q96LI5 | CCR4-NOT transcription complex subunit 6-like | chr4 | GO:0004518 | Not Cancer Driver | No | 58 | 0.105 | 37 | 3 | 0.081 | 0 |
| CNOT6_ENST00000261951 | CNOT6 | Q9ULM6 | CCR4-NOT transcription complex subunit 6 | chr5 | GO:0004518 | Not Cancer Driver | No | 65 | 0.117 | 66 | 4 | 0.061 | 0 |
| CNOT7 | CNOT7 | Q9UIV1 | CCR4-NOT transcription complex subunit 7 | chr8 | GO:0004518 | Not Cancer Driver | No | 31 | 0.109 | 21 | 1 | 0.048 | 0 |
| CNOT8 | CNOT8 | Q9UFF9 | CCR4-NOT transcription complex subunit 8 | chr5 | GO:0004518 | Not Cancer Driver | No | 30 | 0.103 | 6 | 0 | 0.0 | 0 |
| CPSF3 | CPSF3 | Q9UKF6 | Cleavage and polyadenylation specificity factor subunit 3 | chr2 | GO:0004518 | Not Cancer Driver | No | 78 | 0.114 | 56 | 9 | 0.161 | 0 |
| DBR1 | DBR1 | Q9UK59 | Lariat debranching enzyme | chr3 | GO:0004518 | Not Cancer Driver | No | 58 | 0.107 | 185 | 28 | 0.151 | 3 |
| DCLRE1A | DCLRE1A | Q6PJP8 | DNA cross-link repair 1A protein | chr10 | GO:0004518 | Not Cancer Driver | No | 92 | 0.088 | 514 | 45 | 0.088 | 0 |
| DCLRE1B | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0004518 | Not Cancer Driver | No | 65 | 0.122 | 127 | 17 | 0.134 | 0 |
| DCLRE1C | DCLRE1C | Q96SD1 | Protein artemis | chr10 | GO:0004518 | Not Cancer Driver | No | 76 | 0.11 | 277 | 26 | 0.094 | 3 |
| DCP2 | DCP2 | Q8IU60 | m7GpppN-mRNA hydrolase | chr5 | GO:0004518 | Not Cancer Driver | No | 57 | 0.136 | 167 | 24 | 0.144 | 0 |
| DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | GO:0004518 | Not Cancer Driver | No | 48 | 0.142 | 53 | 6 | 0.113 | 1 |
| DDX1 | DDX1 | Q92499 | ATP-dependent RNA helicase DDX1 | chr2 | GO:0004518 | Not Cancer Driver | No | 82 | 0.111 | 91 | 15 | 0.165 | 0 |
| DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | GO:0004518 | Census, Compendium | Yes | 264 | 0.137 | 362 | 45 | 0.124 | 4 |
| DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0004518 | Not Cancer Driver | No | 120 | 0.113 | 52 | 8 | 0.154 | 3 |
| DNASE1L1 | DNASE1L1 | P49184 | Deoxyribonuclease-1-like 1 | chrX | GO:0004518 | Not Cancer Driver | No | 30 | 0.099 | 0 | 0 | 0.0 | 0 |
| DNASE1L2_ENST00000567494 | DNASE1L2 | Q92874 | Deoxyribonuclease-1-like 2 | chr16 | GO:0004518 | Not Cancer Driver | No | 23 | 0.077 | 15 | 1 | 0.067 | 0 |
| DNASE1L3 | DNASE1L3 | Q13609 | Deoxyribonuclease gamma | chr3 | GO:0004518 | Not Cancer Driver | No | 43 | 0.141 | 15 | 4 | 0.267 | 0 |
| DNASE1_ENST00000246949 | DNASE1 | P24855 | Deoxyribonuclease-1 | chr16 | GO:0004518 | Not Cancer Driver | No | 24 | 0.085 | 0 | 0 | 0.0 | 0 |
| DNASE2 | DNASE2 | O00115 | Deoxyribonuclease-2-alpha | chr19 | GO:0004518 | Not Cancer Driver | No | 46 | 0.128 | 48 | 7 | 0.146 | 0 |
| DNASE2B | DNASE2B | Q8WZ79 | Deoxyribonuclease-2-beta | chr1 | GO:0004518 | Not Cancer Driver | No | 53 | 0.147 | 14 | 1 | 0.071 | 0 |
| DROSHA_ENST00000344624 | DROSHA | Q9NRR4 | Ribonuclease 3 | chr5 | GO:0004518 | Census, Compendium | Yes | 175 | 0.127 | 682 | 100 | 0.147 | 0 |
| EDC3 | EDC3 | Q96F86 | Enhancer of mRNA-decapping protein 3 | chr15 | GO:0004518 | Not Cancer Driver | No | 43 | 0.085 | 185 | 22 | 0.119 | 1 |
| ELAC1 | ELAC1 | Q9H777 | Zinc phosphodiesterase ELAC protein 1 | chr18 | GO:0004518 | Not Cancer Driver | No | 40 | 0.11 | 47 | 4 | 0.085 | 0 |
| ELAC2 | ELAC2 | Q9BQ52 | Zinc phosphodiesterase ELAC protein 2 | chr17 | GO:0004518 | Not Cancer Driver | No | 86 | 0.104 | 208 | 30 | 0.144 | 10 |
| ENDOG | ENDOG | Q14249 | Endonuclease G, mitochondrial | chr9 | GO:0004518 | Not Cancer Driver | No | 11 | 0.037 | 61 | 1 | 0.016 | 0 |
| ENDOV | ENDOV | Q8N8Q3 | Endonuclease V | chr17 | GO:0004518 | Not Cancer Driver | No | 28 | 0.099 | 43 | 3 | 0.07 | 0 |
| ENPP1 | ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | chr6 | GO:0004518 | Not Cancer Driver | No | 148 | 0.16 | 101 | 5 | 0.05 | 33 |
| ENPP2_ENST00000075322 | ENPP2 | Q13822 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | chr8 | GO:0004518 | Not Cancer Driver | No | 168 | 0.195 | 81 | 16 | 0.198 | 0 |
| ENPP3_ENST00000357639 | ENPP3 | O14638 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 | chr6 | GO:0004518 | Not Cancer Driver | No | 146 | 0.167 | 57 | 12 | 0.211 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0004518 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0004518 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | GO:0004518 | Not Cancer Driver | No | 58 | 0.093 | 176 | 15 | 0.085 | 0 |
| EXO1_ENST00000348581 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0004518 | Not Cancer Driver | No | 123 | 0.145 | 472 | 76 | 0.161 | 0 |
| EXO5_ENST00000358527 | EXO5 | Q9H790 | Exonuclease V | chr1 | GO:0004518 | Not Cancer Driver | No | 39 | 0.105 | 36 | 3 | 0.083 | 0 |
| EXOG | EXOG | Q9Y2C4 | Nuclease EXOG, mitochondrial | chr3 | GO:0004518 | Not Cancer Driver | No | 42 | 0.114 | 52 | 1 | 0.019 | 0 |
| EXOSC1 | EXOSC1 | Q9Y3B2 | Exosome complex component CSL4 | chr10 | GO:0004518 | Not Cancer Driver | No | 14 | 0.072 | 14 | 2 | 0.143 | 1 |
| EXOSC10 | EXOSC10 | Q01780 | Exosome component 10 | chr1 | GO:0004518 | Not Cancer Driver | No | 87 | 0.098 | 375 | 35 | 0.093 | 0 |
| EXOSC2 | EXOSC2 | Q13868 | Exosome complex component RRP4 | chr9 | GO:0004518 | Not Cancer Driver | No | 21 | 0.072 | 47 | 6 | 0.128 | 2 |
| EXOSC3 | EXOSC3 | Q9NQT5 | Exosome complex component RRP40 | chr9 | GO:0004518 | Not Cancer Driver | No | 18 | 0.065 | 54 | 2 | 0.037 | 4 |
| EXOSC4 | EXOSC4 | Q9NPD3 | Exosome complex component RRP41 | chr8 | GO:0004518 | Not Cancer Driver | No | 34 | 0.139 | 23 | 0 | 0.0 | 0 |
| EXOSC5 | EXOSC5 | Q9NQT4 | Exosome complex component RRP46 | chr19 | GO:0004518 | Not Cancer Driver | No | 43 | 0.183 | 31 | 3 | 0.097 | 0 |
| EXOSC6 | EXOSC6 | Q5RKV6 | Exosome complex component MTR3 | chr16 | GO:0004518 | Not Cancer Driver | No | 3 | 0.011 | 102 | 0 | 0.0 | 0 |
| EXOSC7 | EXOSC7 | Q15024 | Exosome complex component RRP42 | chr3 | GO:0004518 | Not Cancer Driver | No | 41 | 0.141 | 8 | 1 | 0.125 | 0 |
| EXOSC8 | EXOSC8 | Q96B26 | Exosome complex component RRP43 | chr13 | GO:0004518 | Not Cancer Driver | No | 20 | 0.072 | 28 | 1 | 0.036 | 2 |
| EXOSC9_ENST00000243498 | EXOSC9 | Q06265 | Exosome complex component RRP45 | chr4 | GO:0004518 | Not Cancer Driver | No | 58 | 0.132 | 154 | 18 | 0.117 | 1 |
| FAN1 | FAN1 | Q9Y2M0 | Fanconi-associated nuclease 1 | chr15 | GO:0004518 | Not Cancer Driver | No | 124 | 0.122 | 212 | 27 | 0.127 | 4 |
| FANCM | FANCM | Q8IYD8 | Fanconi anemia group M protein | chr14 | GO:0004518 | Not Cancer Driver | No | 268 | 0.131 | 898 | 128 | 0.143 | 0 |
| FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0004518 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
| GEN1_ENST00000381254 | GEN1 | Q17RS7 | Flap endonuclease GEN homolog 1 | chr2 | GO:0004518 | Not Cancer Driver | No | 109 | 0.12 | 339 | 52 | 0.153 | 0 |
| HARBI1 | HARBI1 | Q96MB7 | Putative nuclease HARBI1 | chr11 | GO:0004518 | Not Cancer Driver | No | 40 | 0.115 | 30 | 5 | 0.167 | 0 |
| ISG20 | ISG20 | Q96AZ6 | Interferon-stimulated gene 20 kDa protein | chr15 | GO:0004518 | Not Cancer Driver | No | 20 | 0.11 | 6 | 0 | 0.0 | 0 |
| KIAA0391 | PRORP | O15091 | Mitochondrial ribonuclease P catalytic subunit | chr14 | GO:0004518 | Not Cancer Driver | No | 62 | 0.106 | 60 | 12 | 0.2 | 0 |
| MEIOB_ENST00000397344 | MEIOB | Q8N635 | Meiosis-specific with OB domain-containing protein | chr16 | GO:0004518 | Not Cancer Driver | No | 37 | 0.084 | 21 | 2 | 0.095 | 1 |
| MGME1 | MGME1 | Q9BQP7 | Mitochondrial genome maintenance exonuclease 1 | chr20 | GO:0004518 | Not Cancer Driver | No | 33 | 0.096 | 95 | 7 | 0.074 | 1 |
| MRE11 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0004518 | Not Cancer Driver | No | 84 | 0.119 | 292 | 35 | 0.12 | 1 |
| MRPL44 | MRPL44 | Q9H9J2 | 39S ribosomal protein L44, mitochondrial | chr2 | GO:0004518 | Not Cancer Driver | No | 37 | 0.111 | 45 | 2 | 0.044 | 1 |
| MUS81 | MUS81 | Q96NY9 | Crossover junction endonuclease MUS81 | chr11 | GO:0004518 | Not Cancer Driver | No | 67 | 0.122 | 232 | 38 | 0.164 | 0 |
| NOCT | NOCT | Q9UK39 | Nocturnin | chr4 | GO:0004518 | Not Cancer Driver | No | 33 | 0.077 | 89 | 3 | 0.034 | 0 |
| NUDT12 | NUDT12 | Q9BQG2 | NAD-capped RNA hydrolase NUDT12 | chr5 | GO:0004518 | Not Cancer Driver | No | 65 | 0.141 | 11 | 2 | 0.182 | 0 |
| NUDT16L1 | NUDT16L1 | Q9BRJ7 | Tudor-interacting repair regulator protein | chr16 | GO:0004518 | Not Cancer Driver | No | 16 | 0.076 | 6 | 0 | 0.0 | 0 |
| NUDT16_ENST00000521288 | NUDT16 | Q96DE0 | U8 snoRNA-decapping enzyme | chr3 | GO:0004518 | Not Cancer Driver | No | 29 | 0.149 | 8 | 1 | 0.125 | 0 |
| PAN2_ENST00000548043 | PAN2 | Q504Q3 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | chr12 | GO:0004518 | Not Cancer Driver | No | 139 | 0.116 | 78 | 10 | 0.128 | 0 |
| PAN3 | PAN3 | Q58A45 | PAN2-PAN3 deadenylation complex subunit PAN3 | chr13 | GO:0004518 | Not Cancer Driver | No | 104 | 0.117 | 323 | 35 | 0.108 | 0 |
| PARN | PARN | O95453 | Poly(A)-specific ribonuclease PARN | chr16 | GO:0004518 | Not Cancer Driver | No | 71 | 0.111 | 197 | 22 | 0.112 | 2 |
| PDE12 | PDE12 | Q6L8Q7 | 2',5'-phosphodiesterase 12 | chr3 | GO:0004518 | Not Cancer Driver | No | 59 | 0.097 | 129 | 8 | 0.062 | 0 |
| PLD3_ENST00000409735 | PLD3 | Q8IV08 | 5'-3' exonuclease PLD3 | chr19 | GO:0004518 | Not Cancer Driver | No | 70 | 0.143 | 62 | 7 | 0.113 | 0 |
| PLD4_ENST00000392593 | PLD4 | Q96BZ4 | 5'-3' exonuclease PLD4 | chr14 | GO:0004518 | Not Cancer Driver | No | 46 | 0.091 | 76 | 10 | 0.132 | 0 |
| PLD6 | PLD6 | Q8N2A8 | Mitochondrial cardiolipin hydrolase | chr17 | GO:0004518 | Not Cancer Driver | No | 27 | 0.107 | 24 | 6 | 0.25 | 0 |
| PLSCR1 | PLSCR1 | O15162 | Phospholipid scramblase 1 | chr3 | GO:0004518 | Not Cancer Driver | No | 43 | 0.135 | 92 | 13 | 0.141 | 0 |
| PNLDC1_ENST00000610273 | PNLDC1 | Q8NA58 | Poly(A)-specific ribonuclease PNLDC1 | chr6 | GO:0004518 | Not Cancer Driver | No | 105 | 0.202 | 6 | 0 | 0.0 | 1 |
| POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | GO:0004518 | Census, Compendium | Yes | 409 | 0.179 | 239 | 44 | 0.184 | 3 |
| POP1_ENST00000349693 | POP1 | Q99575 | Ribonucleases P/MRP protein subunit POP1 | chr8 | GO:0004518 | Not Cancer Driver | No | 161 | 0.157 | 495 | 75 | 0.152 | 3 |
| POP4 | POP4 | O95707 | Ribonuclease P protein subunit p29 | chr19 | GO:0004518 | Not Cancer Driver | No | 25 | 0.114 | 53 | 9 | 0.17 | 0 |
| POP5 | POP5 | Q969H6 | Ribonuclease P/MRP protein subunit POP5 | chr12 | GO:0004518 | Not Cancer Driver | No | 17 | 0.104 | 9 | 2 | 0.222 | 0 |
| POP7 | POP7 | O75817 | Ribonuclease P protein subunit p20 | chr7 | GO:0004518 | Not Cancer Driver | No | 20 | 0.143 | 59 | 13 | 0.22 | 0 |
| PPP1R8 | PPP1R8 | Q12972 | Nuclear inhibitor of protein phosphatase 1 | chr1 | GO:0004518 | Not Cancer Driver | No | 24 | 0.068 | 251 | 19 | 0.076 | 0 |
| RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0004518 | Not Cancer Driver | No | 29 | 0.103 | 4 | 1 | 0.25 | 0 |
| RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0004518 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
| RAD51C | RAD51C | O43502 | DNA repair protein RAD51 homolog 3 | chr17 | GO:0004518 | Not Cancer Driver | No | 47 | 0.125 | 18 | 2 | 0.111 | 6 |
| RAD9A | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:0004518 | Not Cancer Driver | No | 34 | 0.087 | 135 | 7 | 0.052 | 0 |
| RAG1 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0004518 | Not Cancer Driver | No | 204 | 0.196 | 208 | 43 | 0.207 | 36 |
| RBBP8_ENST00000327155 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:0004518 | Not Cancer Driver | No | 99 | 0.11 | 750 | 76 | 0.101 | 1 |
| RIDA | RIDA | P52758 | 2-iminobutanoate/2-iminopropanoate deaminase | chr8 | GO:0004518 | Not Cancer Driver | No | 20 | 0.146 | 3 | 0 | 0.0 | 0 |
| RNASE1_ENST00000412779 | RNASE1 | P07998 | Ribonuclease pancreatic | chr14 | GO:0004518 | Not Cancer Driver | No | 17 | 0.109 | 49 | 11 | 0.224 | 0 |
| RNASE2 | RNASE2 | P10153 | Non-secretory ribonuclease | chr14 | GO:0004518 | Not Cancer Driver | No | 30 | 0.186 | 20 | 4 | 0.2 | 0 |
| RNASE4_ENST00000555597 | RNASE4 | P34096 | Ribonuclease 4 | chr14 | GO:0004518 | Not Cancer Driver | No | 24 | 0.163 | 9 | 2 | 0.222 | 0 |
| RNASE8 | RNASE8 | Q8TDE3 | Ribonuclease 8 | chr14 | GO:0004518 | Not Cancer Driver | No | 18 | 0.117 | 17 | 2 | 0.118 | 0 |
| RNASEH1 | RNASEH1 | O60930 | Ribonuclease H1 | chr2 | GO:0004518 | Not Cancer Driver | No | 33 | 0.115 | 124 | 20 | 0.161 | 2 |
| RNASEH2A | RNASEH2A | O75792 | Ribonuclease H2 subunit A | chr19 | GO:0004518 | Not Cancer Driver | No | 42 | 0.14 | 31 | 3 | 0.097 | 7 |
| RNASET2_ENST00000476238 | RNASET2 | O00584 | Ribonuclease T2 | chr6 | GO:0004518 | Not Cancer Driver | No | 32 | 0.125 | 37 | 3 | 0.081 | 1 |
| RPP14_ENST00000295959 | RPP14 | O95059 | Ribonuclease P protein subunit p14 | chr3 | GO:0004518 | Not Cancer Driver | No | 8 | 0.065 | 0 | 0 | 0.0 | 0 |
| RPP21_ENST00000442966 | RPP21 | Q9H633 | Ribonuclease P protein subunit p21 | chr6 | GO:0004518 | Not Cancer Driver | No | 16 | 0.104 | 51 | 4 | 0.078 | 0 |
| RPP25 | RPP25 | Q9BUL9 | Ribonuclease P protein subunit p25 | chr15 | GO:0004518 | Not Cancer Driver | No | 11 | 0.055 | 162 | 11 | 0.068 | 0 |
| RPP30_ENST00000371703 | RPP30 | P78346 | Ribonuclease P protein subunit p30 | chr10 | GO:0004518 | Not Cancer Driver | No | 28 | 0.104 | 21 | 2 | 0.095 | 0 |
| RPP38_ENST00000378202 | RPP38 | P78345 | Ribonuclease P protein subunit p38 | chr10 | GO:0004518 | Not Cancer Driver | No | 36 | 0.127 | 118 | 19 | 0.161 | 0 |
| RPP40 | RPP40 | O75818 | Ribonuclease P protein subunit p40 | chr6 | GO:0004518 | Not Cancer Driver | No | 51 | 0.14 | 5 | 0 | 0.0 | 0 |
| SETMAR | SETMAR | Q53H47 | Histone-lysine N-methyltransferase SETMAR | chr3 | GO:0004518 | Not Cancer Driver | No | 62 | 0.091 | 154 | 12 | 0.078 | 0 |
| SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | GO:0004518 | Not Cancer Driver | No | 3 | 0.011 | 80 | 1 | 0.013 | 0 |
| SND1 | SND1 | Q7KZF4 | Staphylococcal nuclease domain-containing protein 1 | chr7 | GO:0004518 | Census | Yes | 127 | 0.14 | 258 | 48 | 0.186 | 0 |
| TATDN2 | TATDN2 | Q93075 | Putative deoxyribonuclease TATDN2 | chr3 | GO:0004518 | Not Cancer Driver | No | 75 | 0.099 | 472 | 45 | 0.095 | 0 |
| TATDN3_ENST00000366974 | TATDN3 | Q17R31 | Putative deoxyribonuclease TATDN3 | chr1 | GO:0004518 | Not Cancer Driver | No | 37 | 0.135 | 35 | 1 | 0.029 | 0 |
| TDP2 | TDP2 | O95551 | Tyrosyl-DNA phosphodiesterase 2 | chr6 | GO:0004518 | Not Cancer Driver | No | 55 | 0.152 | 80 | 10 | 0.125 | 0 |
| TEFM | TEFM | Q96QE5 | Transcription elongation factor, mitochondrial | chr17 | GO:0004518 | Not Cancer Driver | No | 37 | 0.103 | 26 | 5 | 0.192 | 0 |
| TOE1 | TOE1 | Q96GM8 | Target of EGR1 protein 1 | chr1 | GO:0004518 | Not Cancer Driver | No | 44 | 0.086 | 210 | 22 | 0.105 | 10 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0004518 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TREX2_ENST00000370231 | TREX2 | Q9BQ50 | Three prime repair exonuclease 2 | chrX | GO:0004518 | Not Cancer Driver | No | 33 | 0.14 | 23 | 6 | 0.261 | 0 |
| TSEN15 | TSEN15 | Q8WW01 | tRNA-splicing endonuclease subunit Sen15 | chr1 | GO:0004518 | Not Cancer Driver | No | 27 | 0.158 | 48 | 6 | 0.125 | 3 |
| TSEN2 | TSEN2 | Q8NCE0 | tRNA-splicing endonuclease subunit Sen2 | chr3 | GO:0004518 | Not Cancer Driver | No | 54 | 0.116 | 153 | 17 | 0.111 | 1 |
| TSEN34_ENST00000396383 | TSEN34 | Q9BSV6 | tRNA-splicing endonuclease subunit Sen34 | chr19 | GO:0004518 | Not Cancer Driver | No | 40 | 0.129 | 176 | 22 | 0.125 | 1 |
| USB1 | USB1 | Q9BQ65 | U6 snRNA phosphodiesterase 1 | chr16 | GO:0004518 | Not Cancer Driver | No | 28 | 0.106 | 76 | 5 | 0.066 | 0 |
| XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0004518 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
| XRCC3_ENST00000352127 | XRCC3 | O43542 | DNA repair protein XRCC3 | chr14 | GO:0004518 | Not Cancer Driver | No | 24 | 0.069 | 35 | 2 | 0.057 | 1 |
| XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | GO:0004518 | Not Cancer Driver | No | 213 | 0.125 | 577 | 65 | 0.113 | 0 |
| XRN2 | XRN2 | Q9H0D6 | 5'-3' exoribonuclease 2 | chr20 | GO:0004518 | Not Cancer Driver | No | 129 | 0.136 | 427 | 63 | 0.148 | 0 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0004518 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
| ZGRF1 | ZGRF1 | Q86YA3 | Protein ZGRF1 | chr4 | GO:0004518 | Not Cancer Driver | No | 216 | 0.103 | 881 | 95 | 0.108 | 0 |