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Total number of protein in "GO:0004386" GO term:  107

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AQR AQR O60306 RNA helicase aquarius chr15 GO:0004386 Not Cancer Driver No 201 0.135 297 31 0.104 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0004386 Census Yes 153 0.108 667 70 0.105 8
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0004386 Census Yes 174 0.139 397 59 0.149 6
BTAF1 BTAF1 O14981 TATA-binding protein-associated factor 172 chr10 GO:0004386 Not Cancer Driver No 215 0.116 360 52 0.144 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 GO:0004386 Not Cancer Driver No 235 0.117 1015 122 0.12 18
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0004386 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX10 DDX10 Q13206 Probable ATP-dependent RNA helicase DDX10 chr11 GO:0004386 Census Yes 93 0.106 400 46 0.115 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0004386 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 GO:0004386 Not Cancer Driver No 91 0.125 362 48 0.133 0
DDX18 DDX18 Q9NVP1 ATP-dependent RNA helicase DDX18 chr2 GO:0004386 Not Cancer Driver No 111 0.166 239 36 0.151 0
DDX19A DDX19A Q9NUU7 ATP-dependent RNA helicase DDX19A chr16 GO:0004386 Not Cancer Driver No 37 0.077 112 11 0.098 0
DDX19B DDX19B Q9UMR2 ATP-dependent RNA helicase DDX19B chr16 GO:0004386 Not Cancer Driver No 44 0.092 113 9 0.08 0
DDX20 DDX20 Q9UHI6 Probable ATP-dependent RNA helicase DDX20 chr1 GO:0004386 Not Cancer Driver No 89 0.108 299 33 0.11 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0004386 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX23 DDX23 Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 chr12 GO:0004386 Not Cancer Driver No 121 0.148 426 71 0.167 0
DDX24 DDX24 Q9GZR7 ATP-dependent RNA helicase DDX24 chr14 GO:0004386 Not Cancer Driver No 86 0.1 452 40 0.088 0
DDX25 DDX25 Q9UHL0 ATP-dependent RNA helicase DDX25 chr11 GO:0004386 Not Cancer Driver No 54 0.112 39 4 0.103 0
DDX27 DDX27 Q96GQ7 Probable ATP-dependent RNA helicase DDX27 chr20 GO:0004386 Not Cancer Driver No 101 0.127 383 50 0.131 0
DDX28 DDX28 Q9NUL7 Probable ATP-dependent RNA helicase DDX28 chr16 GO:0004386 Not Cancer Driver No 37 0.069 127 3 0.024 0
DDX31_ENST00000372153 DDX31 Q9H8H2 Probable ATP-dependent RNA helicase DDX31 chr9 GO:0004386 Not Cancer Driver No 99 0.116 342 38 0.111 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 GO:0004386 Not Cancer Driver No 44 0.103 37 2 0.054 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 GO:0004386 Not Cancer Driver No 49 0.114 34 8 0.235 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0004386 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX3Y_ENST00000336079 DDX3Y O15523 ATP-dependent RNA helicase DDX3Y chrY GO:0004386 Not Cancer Driver No 31 0.047 289 18 0.062 0
DDX4 DDX4 Q9NQI0 Probable ATP-dependent RNA helicase DDX4 chr5 GO:0004386 Not Cancer Driver No 115 0.159 315 49 0.156 0
DDX41 DDX41 Q9UJV9 Probable ATP-dependent RNA helicase DDX41 chr5 GO:0004386 Not Cancer Driver No 82 0.132 180 26 0.144 1
DDX42 DDX42 Q86XP3 ATP-dependent RNA helicase DDX42 chr17 GO:0004386 Not Cancer Driver No 126 0.134 607 79 0.13 0
DDX43 DDX43 Q9NXZ2 Probable ATP-dependent RNA helicase DDX43 chr6 GO:0004386 Not Cancer Driver No 103 0.159 231 46 0.199 0
DDX46_ENST00000354283 DDX46 Q7L014 Probable ATP-dependent RNA helicase DDX46 chr5 GO:0004386 Not Cancer Driver No 120 0.116 510 72 0.141 0
DDX47 DDX47 Q9H0S4 Probable ATP-dependent RNA helicase DDX47 chr12 GO:0004386 Not Cancer Driver No 51 0.112 98 7 0.071 0
DDX49 DDX49 Q9Y6V7 Probable ATP-dependent RNA helicase DDX49 chr19 GO:0004386 Not Cancer Driver No 55 0.114 78 6 0.077 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0004386 Census Yes 74 0.121 225 23 0.102 0
DDX50 DDX50 Q9BQ39 ATP-dependent RNA helicase DDX50 chr10 GO:0004386 Not Cancer Driver No 86 0.117 274 30 0.109 0
DDX51 DDX51 Q8N8A6 ATP-dependent RNA helicase DDX51 chr12 GO:0004386 Not Cancer Driver No 51 0.077 244 8 0.033 0
DDX53 DDX53 Q86TM3 Probable ATP-dependent RNA helicase DDX53 chrX GO:0004386 Not Cancer Driver No 113 0.179 199 42 0.211 0
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 GO:0004386 Not Cancer Driver No 113 0.128 458 52 0.114 0
DDX55 DDX55 Q8NHQ9 ATP-dependent RNA helicase DDX55 chr12 GO:0004386 Not Cancer Driver No 51 0.085 130 6 0.046 0
DDX56 DDX56 Q9NY93 Probable ATP-dependent RNA helicase DDX56 chr7 GO:0004386 Not Cancer Driver No 50 0.091 107 13 0.121 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0004386 Not Cancer Driver No 118 0.128 61 10 0.164 2
DDX59 DDX59 Q5T1V6 Probable ATP-dependent RNA helicase DDX59 chr1 GO:0004386 Not Cancer Driver No 83 0.134 174 26 0.149 2
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 GO:0004386 Census, Compendium Yes 44 0.091 129 7 0.054 5
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0004386 Not Cancer Driver No 224 0.131 131 12 0.092 0
DDX60L DDX60L Q5H9U9 Probable ATP-dependent RNA helicase DDX60-like chr4 GO:0004386 Not Cancer Driver No 219 0.128 84 10 0.119 0
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 GO:0004386 Not Cancer Driver No 110 0.138 180 30 0.167 0
DHX16 DHX16 O60231 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 chr6 GO:0004386 Not Cancer Driver No 128 0.123 391 59 0.151 1
DHX29 DHX29 Q7Z478 ATP-dependent RNA helicase DHX29 chr5 GO:0004386 Not Cancer Driver No 146 0.107 405 34 0.084 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 GO:0004386 Not Cancer Driver No 165 0.138 260 40 0.154 6
DHX32 DHX32 Q7L7V1 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 chr10 GO:0004386 Not Cancer Driver No 88 0.118 60 8 0.133 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0004386 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX34 DHX34 Q14147 Probable ATP-dependent RNA helicase DHX34 chr19 GO:0004386 Not Cancer Driver No 175 0.153 326 41 0.126 0
DHX35 DHX35 Q9H5Z1 Probable ATP-dependent RNA helicase DHX35 chr20 GO:0004386 Not Cancer Driver No 91 0.129 47 6 0.128 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0004386 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX37 DHX37 Q8IY37 Probable ATP-dependent RNA helicase DHX37 chr12 GO:0004386 Not Cancer Driver No 165 0.143 433 66 0.152 5
DHX38 DHX38 Q92620 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 chr16 GO:0004386 Not Cancer Driver No 139 0.113 622 83 0.133 1
DHX40 DHX40 Q8IX18 Probable ATP-dependent RNA helicase DHX40 chr17 GO:0004386 Not Cancer Driver No 90 0.116 166 24 0.145 0
DHX57 DHX57 Q6P158 Putative ATP-dependent RNA helicase DHX57 chr2 GO:0004386 Not Cancer Driver No 147 0.106 294 32 0.109 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0004386 Not Cancer Driver No 62 0.091 84 8 0.095 0
DHX8 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 GO:0004386 Not Cancer Driver No 138 0.113 490 72 0.147 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0004386 Compendium Yes 182 0.143 331 42 0.127 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0004386 Census, Compendium Yes 264 0.137 362 45 0.124 4
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0004386 Not Cancer Driver No 120 0.113 52 8 0.154 3
EIF4A1 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 GO:0004386 Not Cancer Driver No 48 0.118 35 7 0.2 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 GO:0004386 Census Yes 77 0.189 27 14 0.519 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0004386 Not Cancer Driver No 50 0.122 57 6 0.105 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 GO:0004386 Not Cancer Driver No 397 0.126 2064 234 0.113 0
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0004386 Census, Compendium Yes 150 0.197 5 0 0.0 35
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0004386 Not Cancer Driver No 268 0.131 898 128 0.143 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0004386 Not Cancer Driver No 85 0.182 352 65 0.185 0
HELB HELB Q8NG08 DNA helicase B chr12 GO:0004386 Not Cancer Driver No 140 0.129 300 38 0.127 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0004386 Not Cancer Driver No 78 0.093 227 25 0.11 0
HELQ HELQ Q8TDG4 Helicase POLQ-like chr4 GO:0004386 Not Cancer Driver No 134 0.122 273 19 0.07 0
HELZ2 HELZ2 Q9BYK8 Helicase with zinc finger domain 2 chr20 GO:0004386 Not Cancer Driver No 320 0.121 594 84 0.141 0
HELZ_ENST00000358691 HELZ P42694 Probable helicase with zinc finger domain chr17 GO:0004386 Not Cancer Driver No 234 0.12 873 110 0.126 0
HLTF_ENST00000494055 HLTF Q14527 Helicase-like transcription factor chr3 GO:0004386 Not Cancer Driver No 121 0.12 353 40 0.113 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0004386 Not Cancer Driver No 109 0.106 287 36 0.125 9
IGHMBP2 IGHMBP2 P38935 DNA-binding protein SMUBP-2 chr11 GO:0004386 Not Cancer Driver No 136 0.137 354 53 0.15 31
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 GO:0004386 Not Cancer Driver No 101 0.123 122 13 0.107 0
MOV10L1_ENST00000545383 MOV10L1 Q9BXT6 RNA helicase Mov10l1 chr22 GO:0004386 Not Cancer Driver No 184 0.152 178 21 0.118 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:0004386 Not Cancer Driver No 110 0.11 101 8 0.079 0
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 GO:0004386 Not Cancer Driver No 117 0.112 160 15 0.094 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0004386 Not Cancer Driver No 54 0.084 209 11 0.053 0
RAD54B RAD54B Q9Y620 DNA repair and recombination protein RAD54B chr8 GO:0004386 Not Cancer Driver No 112 0.123 120 16 0.133 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 GO:0004386 Census, Compendium Yes 138 0.114 608 71 0.117 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0004386 Not Cancer Driver No 132 0.133 495 71 0.143 0
RECQL_ENST00000421138 RECQL P46063 ATP-dependent DNA helicase Q1 chr12 GO:0004386 Not Cancer Driver No 67 0.103 91 5 0.055 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0004386 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0004386 Not Cancer Driver No 62 0.134 100 13 0.13 0
SHPRH SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 GO:0004386 Not Cancer Driver No 227 0.135 359 51 0.142 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 GO:0004386 Not Cancer Driver No 140 0.112 390 54 0.138 1
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:0004386 Not Cancer Driver No 177 0.196 34 8 0.235 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX GO:0004386 Compendium Yes 143 0.136 309 41 0.133 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 GO:0004386 Not Cancer Driver No 273 0.172 1009 160 0.159 42
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0004386 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0004386 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0004386 Not Cancer Driver No 128 0.134 335 49 0.146 11
SNRNP200 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 GO:0004386 Not Cancer Driver No 237 0.111 270 37 0.137 11
SRCAP SRCAP Q6ZRS2 Helicase SRCAP chr16 GO:0004386 Not Cancer Driver No 438 0.136 2534 340 0.134 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0004386 Not Cancer Driver No 72 0.092 140 12 0.086 0
TDRD12_ENST00000444215 TDRD12 Q587J7 Putative ATP-dependent RNA helicase TDRD12 chr19 GO:0004386 Not Cancer Driver No 36 0.031 220 10 0.045 0
TDRD9 TDRD9 Q8NDG6 ATP-dependent RNA helicase TDRD9 chr14 GO:0004386 Not Cancer Driver No 156 0.113 108 0 0.0 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 GO:0004386 Not Cancer Driver No 118 0.102 550 50 0.091 0
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 GO:0004386 Not Cancer Driver No 95 0.139 135 11 0.081 38
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0004386 Not Cancer Driver No 146 0.129 329 36 0.109 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0004386 Census, Compendium Yes 164 0.115 373 41 0.11 2
YTHDC2 YTHDC2 Q9H6S0 3'-5' RNA helicase YTHDC2 chr5 GO:0004386 Not Cancer Driver No 163 0.114 439 48 0.109 0
ZGRF1 ZGRF1 Q86YA3 Protein ZGRF1 chr4 GO:0004386 Not Cancer Driver No 216 0.103 881 95 0.108 0
ZNFX1_ENST00000371752 ZNFX1 Q9P2E3 NFX1-type zinc finger-containing protein 1 chr20 GO:0004386 Not Cancer Driver No 228 0.119 354 49 0.138 0