Total number of protein in "GO:0004197" GO term: 104
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADGB | ADGB | Q8N7X0 | Androglobin | chr6 | GO:0004197 | Not Cancer Driver | No | 141 | 0.085 | 706 | 68 | 0.096 | 0 |
| ATG4A | ATG4A | Q8WYN0 | Cysteine protease ATG4A | chrX | GO:0004197 | Not Cancer Driver | No | 54 | 0.136 | 53 | 0 | 0.0 | 0 |
| ATG4B | ATG4B | Q9Y4P1 | Cysteine protease ATG4B | chr2 | GO:0004197 | Not Cancer Driver | No | 34 | 0.087 | 13 | 2 | 0.154 | 0 |
| ATG4C_ENST00000371120 | ATG4C | Q96DT6 | Cysteine protease ATG4C | chr1 | GO:0004197 | Not Cancer Driver | No | 62 | 0.135 | 17 | 3 | 0.176 | 0 |
| BLMH | BLMH | Q13867 | Bleomycin hydrolase | chr17 | GO:0004197 | Not Cancer Driver | No | 54 | 0.119 | 15 | 1 | 0.067 | 0 |
| CAPN10 | CAPN10 | Q9HC96 | Calpain-10 | chr2 | GO:0004197 | Not Cancer Driver | No | 87 | 0.129 | 52 | 6 | 0.115 | 0 |
| CAPN11 | CAPN11 | Q9UMQ6 | Calpain-11 | chr6 | GO:0004197 | Not Cancer Driver | No | 96 | 0.13 | 103 | 12 | 0.117 | 0 |
| CAPN12 | CAPN12 | Q6ZSI9 | Calpain-12 | chr19 | GO:0004197 | Not Cancer Driver | No | 83 | 0.115 | 62 | 9 | 0.145 | 0 |
| CAPN13 | CAPN13 | Q6MZZ7 | Calpain-13 | chr2 | GO:0004197 | Not Cancer Driver | No | 155 | 0.232 | 73 | 24 | 0.329 | 0 |
| CAPN14 | CAPN14 | A8MX76 | Calpain-14 | chr2 | GO:0004197 | Not Cancer Driver | No | 47 | 0.069 | 22 | 2 | 0.091 | 0 |
| CAPN15 | CAPN15 | O75808 | Calpain-15 | chr16 | GO:0004197 | Not Cancer Driver | No | 98 | 0.09 | 385 | 29 | 0.075 | 0 |
| CAPN1_ENST00000533129 | CAPN1 | P07384 | Calpain-1 catalytic subunit | chr11 | GO:0004197 | Not Cancer Driver | No | 68 | 0.095 | 32 | 2 | 0.062 | 1 |
| CAPN2 | CAPN2 | P17655 | Calpain-2 catalytic subunit | chr1 | GO:0004197 | Not Cancer Driver | No | 81 | 0.116 | 46 | 11 | 0.239 | 0 |
| CAPN3 | CAPN3 | P20807 | Calpain-3 | chr15 | GO:0004197 | Not Cancer Driver | No | 111 | 0.135 | 168 | 11 | 0.065 | 52 |
| CAPN5 | CAPN5 | O15484 | Calpain-5 | chr11 | GO:0004197 | Not Cancer Driver | No | 103 | 0.161 | 110 | 25 | 0.227 | 2 |
| CAPN6 | CAPN6 | Q9Y6Q1 | Calpain-6 | chrX | GO:0004197 | Not Cancer Driver | No | 156 | 0.243 | 19 | 8 | 0.421 | 0 |
| CAPN7 | CAPN7 | Q9Y6W3 | Calpain-7 | chr3 | GO:0004197 | Not Cancer Driver | No | 80 | 0.098 | 92 | 9 | 0.098 | 0 |
| CAPN8 | CAPN8 | A6NHC0 | Calpain-8 | chr1 | GO:0004197 | Not Cancer Driver | No | 36 | 0.051 | 76 | 6 | 0.079 | 0 |
| CAPN9 | CAPN9 | O14815 | Calpain-9 | chr1 | GO:0004197 | Not Cancer Driver | No | 110 | 0.159 | 81 | 17 | 0.21 | 0 |
| CAPNS1 | CAPNS1 | P04632 | Calpain small subunit 1 | chr19 | GO:0004197 | Not Cancer Driver | No | 30 | 0.112 | 58 | 5 | 0.086 | 0 |
| CAPNS2 | CAPNS2 | Q96L46 | Calpain small subunit 2 | chr16 | GO:0004197 | Not Cancer Driver | No | 21 | 0.085 | 56 | 5 | 0.089 | 0 |
| CASP1 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0004197 | Not Cancer Driver | No | 79 | 0.196 | 87 | 18 | 0.207 | 0 |
| CASP10_ENST00000272879 | CASP10 | Q92851 | Caspase-10 | chr2 | GO:0004197 | Not Cancer Driver | No | 57 | 0.109 | 126 | 17 | 0.135 | 3 |
| CASP12 | CASP12 | Q6UXS9 | Inactive caspase-12 | chr11 | GO:0004197 | Not Cancer Driver | No | 12 | 0.035 | 31 | 1 | 0.032 | 0 |
| CASP14 | CASP14 | P31944 | Caspase-14 | chr19 | GO:0004197 | Not Cancer Driver | No | 50 | 0.207 | 84 | 13 | 0.155 | 0 |
| CASP2 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0004197 | Not Cancer Driver | No | 63 | 0.139 | 42 | 12 | 0.286 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0004197 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CASP4 | CASP4 | P49662 | Caspase-4 | chr11 | GO:0004197 | Not Cancer Driver | No | 56 | 0.149 | 102 | 14 | 0.137 | 0 |
| CASP5_ENST00000260315 | CASP5 | P51878 | Caspase-5 | chr11 | GO:0004197 | Not Cancer Driver | No | 103 | 0.237 | 61 | 17 | 0.279 | 0 |
| CASP6 | CASP6 | P55212 | Caspase-6 | chr4 | GO:0004197 | Not Cancer Driver | No | 28 | 0.096 | 24 | 4 | 0.167 | 0 |
| CASP7_ENST00000345633 | CASP7 | P55210 | Caspase-7 | chr10 | GO:0004197 | Not Cancer Driver | No | 38 | 0.125 | 73 | 10 | 0.137 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0004197 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0004197 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CFLAR | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0004197 | Not Cancer Driver | No | 40 | 0.083 | 44 | 2 | 0.045 | 0 |
| CTSB | CTSB | P07858 | Cathepsin B | chr8 | GO:0004197 | Not Cancer Driver | No | 41 | 0.121 | 7 | 2 | 0.286 | 0 |
| CTSC | CTSC | P53634 | Dipeptidyl peptidase 1 | chr11 | GO:0004197 | Not Cancer Driver | No | 64 | 0.138 | 19 | 5 | 0.263 | 29 |
| CTSD | CTSD | P07339 | Cathepsin D | chr11 | GO:0004197 | Not Cancer Driver | No | 57 | 0.138 | 6 | 1 | 0.167 | 2 |
| CTSF | CTSF | Q9UBX1 | Cathepsin F | chr11 | GO:0004197 | Not Cancer Driver | No | 63 | 0.13 | 78 | 7 | 0.09 | 4 |
| CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0004197 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
| CTSK | CTSK | P43235 | Cathepsin K | chr1 | GO:0004197 | Not Cancer Driver | No | 36 | 0.109 | 24 | 4 | 0.167 | 6 |
| CTSL | CTSL | P07711 | Procathepsin L | chr9 | GO:0004197 | Not Cancer Driver | No | 47 | 0.141 | 34 | 4 | 0.118 | 0 |
| CTSO | CTSO | P43234 | Cathepsin O | chr4 | GO:0004197 | Not Cancer Driver | No | 39 | 0.121 | 8 | 0 | 0.0 | 0 |
| CTSS | CTSS | P25774 | Cathepsin S | chr1 | GO:0004197 | Not Cancer Driver | No | 54 | 0.163 | 0 | 0 | 0.0 | 0 |
| CTSV | CTSV | O60911 | Cathepsin L2 | chr9 | GO:0004197 | Not Cancer Driver | No | 55 | 0.165 | 7 | 1 | 0.143 | 0 |
| CTSW | CTSW | P56202 | Cathepsin W | chr11 | GO:0004197 | Not Cancer Driver | No | 58 | 0.154 | 59 | 10 | 0.169 | 0 |
| CTSZ | CTSZ | Q9UBR2 | Cathepsin Z | chr20 | GO:0004197 | Not Cancer Driver | No | 30 | 0.099 | 10 | 0 | 0.0 | 0 |
| ESPL1 | ESPL1 | Q14674 | Separin | chr12 | GO:0004197 | Not Cancer Driver | No | 211 | 0.1 | 380 | 39 | 0.103 | 0 |
| GPAA1 | GPAA1 | O43292 | Glycosylphosphatidylinositol anchor attachment 1 protein | chr8 | GO:0004197 | Not Cancer Driver | No | 55 | 0.089 | 20 | 3 | 0.15 | 5 |
| LGMN_ENST00000334869 | LGMN | Q99538 | Legumain | chr14 | GO:0004197 | Not Cancer Driver | No | 57 | 0.132 | 112 | 19 | 0.17 | 0 |
| MALT1 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | GO:0004197 | Census, Compendium | Yes | 75 | 0.091 | 139 | 12 | 0.086 | 1 |
| PDIA3 | PDIA3 | P30101 | Protein disulfide-isomerase A3 | chr15 | GO:0004197 | Not Cancer Driver | No | 57 | 0.113 | 98 | 11 | 0.112 | 0 |
| PIGK | PIGK | Q92643 | GPI-anchor transamidase | chr1 | GO:0004197 | Not Cancer Driver | No | 54 | 0.137 | 37 | 9 | 0.243 | 5 |
| PYDC1 | PYDC1 | Q8WXC3 | Pyrin domain-containing protein 1 | chr16 | GO:0004197 | Not Cancer Driver | No | 28 | 0.315 | 0 | 0 | 0.0 | 0 |
| RCE1 | RCE1 | Q9Y256 | CAAX prenyl protease 2 | chr11 | GO:0004197 | Not Cancer Driver | No | 40 | 0.122 | 0 | 0 | 0.0 | 0 |
| SENP1 | SENP1 | Q9P0U3 | Sentrin-specific protease 1 | chr12 | GO:0004197 | Not Cancer Driver | No | 64 | 0.099 | 355 | 44 | 0.124 | 0 |
| SENP2 | SENP2 | Q9HC62 | Sentrin-specific protease 2 | chr3 | GO:0004197 | Not Cancer Driver | No | 73 | 0.124 | 285 | 38 | 0.133 | 0 |
| SENP5 | SENP5 | Q96HI0 | Sentrin-specific protease 5 | chr3 | GO:0004197 | Not Cancer Driver | No | 85 | 0.113 | 293 | 34 | 0.116 | 0 |
| SENP6 | SENP6 | Q9GZR1 | Sentrin-specific protease 6 | chr6 | GO:0004197 | Not Cancer Driver | No | 120 | 0.108 | 612 | 59 | 0.096 | 0 |
| SENP7 | SENP7 | Q9BQF6 | Sentrin-specific protease 7 | chr3 | GO:0004197 | Not Cancer Driver | No | 149 | 0.142 | 523 | 73 | 0.14 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0004197 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| TINAG | TINAG | Q9UJW2 | Tubulointerstitial nephritis antigen | chr6 | GO:0004197 | Not Cancer Driver | No | 141 | 0.296 | 62 | 22 | 0.355 | 0 |
| UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | GO:0004197 | Not Cancer Driver | No | 33 | 0.148 | 34 | 7 | 0.206 | 4 |
| USP10_ENST00000219473 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | GO:0004197 | Not Cancer Driver | No | 92 | 0.115 | 425 | 49 | 0.115 | 0 |
| USP11 | USP11 | P51784 | Ubiquitin carboxyl-terminal hydrolase 11 | chrX | GO:0004197 | Not Cancer Driver | No | 140 | 0.145 | 210 | 28 | 0.133 | 0 |
| USP12 | USP12 | O75317 | Ubiquitin carboxyl-terminal hydrolase 12 | chr13 | GO:0004197 | Not Cancer Driver | No | 55 | 0.149 | 33 | 5 | 0.152 | 0 |
| USP13 | USP13 | Q92995 | Ubiquitin carboxyl-terminal hydrolase 13 | chr3 | GO:0004197 | Not Cancer Driver | No | 121 | 0.14 | 224 | 42 | 0.188 | 0 |
| USP14 | USP14 | P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | chr18 | GO:0004197 | Not Cancer Driver | No | 59 | 0.119 | 86 | 6 | 0.07 | 0 |
| USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | GO:0004197 | Not Cancer Driver | No | 136 | 0.139 | 259 | 39 | 0.151 | 0 |
| USP16 | USP16 | Q9Y5T5 | Ubiquitin carboxyl-terminal hydrolase 16 | chr21 | GO:0004197 | Not Cancer Driver | No | 98 | 0.119 | 394 | 42 | 0.107 | 0 |
| USP17L1 | USP17L1 | Q7RTZ2 | Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 | chr8 | GO:0004197 | Not Cancer Driver | No | 7 | 0.013 | 192 | 1 | 0.005 | 0 |
| USP17L10 | USP17L10 | C9JJH3 | Ubiquitin carboxyl-terminal hydrolase 17-like protein 10 | chr4 | GO:0004197 | Not Cancer Driver | No | 1 | 0.002 | 197 | 0 | 0.0 | 0 |
| USP17L18 | USP17L18 | D6R9N7 | Ubiquitin carboxyl-terminal hydrolase 17-like protein 18 | chr4 | GO:0004197 | Not Cancer Driver | No | 2 | 0.004 | 200 | 1 | 0.005 | 0 |
| USP17L2 | USP17L2 | Q6R6M4 | Ubiquitin carboxyl-terminal hydrolase 17 | chr8 | GO:0004197 | Not Cancer Driver | No | 105 | 0.198 | 201 | 54 | 0.269 | 0 |
| USP17L7 | USP17L7 | P0C7H9 | Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7 | chr8 | GO:0004197 | Not Cancer Driver | No | 6 | 0.011 | 169 | 2 | 0.012 | 0 |
| USP18 | USP18 | Q9UMW8 | Ubl carboxyl-terminal hydrolase 18 | chr22 | GO:0004197 | Not Cancer Driver | No | 34 | 0.091 | 29 | 8 | 0.276 | 0 |
| USP1_ENST00000371146 | USP1 | O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | chr1 | GO:0004197 | Not Cancer Driver | No | 63 | 0.08 | 403 | 30 | 0.074 | 0 |
| USP2 | USP2 | O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | chr11 | GO:0004197 | Not Cancer Driver | No | 88 | 0.145 | 213 | 39 | 0.183 | 0 |
| USP20_ENST00000358355 | USP20 | Q9Y2K6 | Ubiquitin carboxyl-terminal hydrolase 20 | chr9 | GO:0004197 | Not Cancer Driver | No | 112 | 0.123 | 295 | 36 | 0.122 | 0 |
| USP24 | USP24 | Q9UPU5 | Ubiquitin carboxyl-terminal hydrolase 24 | chr1 | GO:0004197 | Not Cancer Driver | No | 229 | 0.087 | 430 | 27 | 0.063 | 0 |
| USP25_ENST00000285679 | USP25 | Q9UHP3 | Ubiquitin carboxyl-terminal hydrolase 25 | chr21 | GO:0004197 | Not Cancer Driver | No | 135 | 0.128 | 354 | 55 | 0.155 | 0 |
| USP26 | USP26 | Q9BXU7 | Ubiquitin carboxyl-terminal hydrolase 26 | chrX | GO:0004197 | Not Cancer Driver | No | 206 | 0.226 | 325 | 75 | 0.231 | 0 |
| USP27X | USP27X | A6NNY8 | Ubiquitin carboxyl-terminal hydrolase 27 | chrX | GO:0004197 | Not Cancer Driver | No | 31 | 0.071 | 69 | 3 | 0.043 | 1 |
| USP28 | USP28 | Q96RU2 | Ubiquitin carboxyl-terminal hydrolase 28 | chr11 | GO:0004197 | Not Cancer Driver | No | 151 | 0.14 | 311 | 25 | 0.08 | 0 |
| USP29_ENST00000598197 | USP29 | Q9HBJ7 | Ubiquitin carboxyl-terminal hydrolase 29 | chr19 | GO:0004197 | Not Cancer Driver | No | 291 | 0.316 | 432 | 132 | 0.306 | 0 |
| USP30 | USP30 | Q70CQ3 | Ubiquitin carboxyl-terminal hydrolase 30 | chr12 | GO:0004197 | Not Cancer Driver | No | 76 | 0.147 | 136 | 26 | 0.191 | 0 |
| USP33_ENST00000357428 | USP33 | Q8TEY7 | Ubiquitin carboxyl-terminal hydrolase 33 | chr1 | GO:0004197 | Not Cancer Driver | No | 138 | 0.146 | 256 | 48 | 0.188 | 0 |
| USP34 | USP34 | Q70CQ2 | Ubiquitin carboxyl-terminal hydrolase 34 | chr2 | GO:0004197 | Not Cancer Driver | No | 436 | 0.123 | 725 | 90 | 0.124 | 0 |
| USP35 | USP35 | Q9P2H5 | Ubiquitin carboxyl-terminal hydrolase 35 | chr11 | GO:0004197 | Not Cancer Driver | No | 116 | 0.114 | 282 | 49 | 0.174 | 0 |
| USP36_ENST00000312010 | USP36 | Q9P275 | Ubiquitin carboxyl-terminal hydrolase 36 | chr17 | GO:0004197 | Not Cancer Driver | No | 151 | 0.134 | 718 | 91 | 0.127 | 0 |
| USP37_ENST00000454775 | USP37 | Q86T82 | Ubiquitin carboxyl-terminal hydrolase 37 | chr2 | GO:0004197 | Not Cancer Driver | No | 112 | 0.114 | 530 | 62 | 0.117 | 0 |
| USP38 | USP38 | Q8NB14 | Ubiquitin carboxyl-terminal hydrolase 38 | chr4 | GO:0004197 | Not Cancer Driver | No | 94 | 0.09 | 180 | 21 | 0.117 | 0 |
| USP40_ENST00000427112 | USP40 | Q9NVE5 | Ubiquitin carboxyl-terminal hydrolase 40 | chr2 | GO:0004197 | Not Cancer Driver | No | 153 | 0.124 | 218 | 26 | 0.119 | 0 |
| USP41 | USP41 | Q3LFD5 | Putative ubiquitin carboxyl-terminal hydrolase 41 | chr22 | GO:0004197 | Not Cancer Driver | No | 38 | 0.106 | 8 | 0 | 0.0 | 0 |
| USP42 | USP42 | Q9H9J4 | Ubiquitin carboxyl-terminal hydrolase 42 | chr7 | GO:0004197 | Not Cancer Driver | No | 141 | 0.106 | 958 | 106 | 0.111 | 0 |
| USP46 | USP46 | P62068 | Ubiquitin carboxyl-terminal hydrolase 46 | chr4 | GO:0004197 | Not Cancer Driver | No | 48 | 0.131 | 28 | 4 | 0.143 | 0 |
| USP47 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0004197 | Not Cancer Driver | No | 137 | 0.1 | 425 | 39 | 0.092 | 0 |
| USP48 | USP48 | Q86UV5 | Ubiquitin carboxyl-terminal hydrolase 48 | chr1 | GO:0004197 | Not Cancer Driver | No | 125 | 0.121 | 178 | 21 | 0.118 | 0 |
| USP49 | USP49 | Q70CQ1 | Ubiquitin carboxyl-terminal hydrolase 49 | chr6 | GO:0004197 | Not Cancer Driver | No | 81 | 0.118 | 190 | 19 | 0.1 | 0 |
| USP5 | USP5 | P45974 | Ubiquitin carboxyl-terminal hydrolase 5 | chr12 | GO:0004197 | Not Cancer Driver | No | 117 | 0.136 | 262 | 38 | 0.145 | 0 |
| USP6 | USP6 | P35125 | Ubiquitin carboxyl-terminal hydrolase 6 | chr17 | GO:0004197 | Census, Compendium | Yes | 243 | 0.173 | 537 | 83 | 0.155 | 0 |
| USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | GO:0004197 | Not Cancer Driver | No | 170 | 0.154 | 215 | 45 | 0.209 | 0 |
| USP8 | USP8 | P40818 | Ubiquitin carboxyl-terminal hydrolase 8 | chr15 | GO:0004197 | Census, Compendium | Yes | 122 | 0.109 | 602 | 69 | 0.115 | 0 |
| USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0004197 | Census, Compendium | Yes | 339 | 0.133 | 405 | 51 | 0.126 | 1 |
| USP9Y | USP9Y | O00507 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y | chrY | GO:0004197 | Not Cancer Driver | No | 83 | 0.032 | 349 | 6 | 0.017 | 0 |