Total number of protein in "GO:0004114" GO term: 20
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDE10A_ENST00000366882 | PDE10A | Q9Y233 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | chr6 | GO:0004114 | Not Cancer Driver | No | 198 | 0.254 | 79 | 21 | 0.266 | 4 |
| PDE1A_ENST00000410103 | PDE1A | P54750 | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | chr2 | GO:0004114 | Not Cancer Driver | No | 157 | 0.293 | 61 | 7 | 0.115 | 0 |
| PDE1B | PDE1B | Q01064 | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | chr12 | GO:0004114 | Not Cancer Driver | No | 114 | 0.213 | 132 | 30 | 0.227 | 0 |
| PDE1C_ENST00000321453 | PDE1C | Q14123 | Dual specificity Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | chr7 | GO:0004114 | Not Cancer Driver | No | 253 | 0.357 | 281 | 97 | 0.345 | 1 |
| PDE2A | PDE2A | O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | chr11 | GO:0004114 | Not Cancer Driver | No | 137 | 0.146 | 99 | 7 | 0.071 | 0 |
| PDE3A | PDE3A | Q14432 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | chr12 | GO:0004114 | Not Cancer Driver | No | 274 | 0.24 | 527 | 114 | 0.216 | 6 |
| PDE3B | PDE3B | Q13370 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | chr11 | GO:0004114 | Not Cancer Driver | No | 135 | 0.121 | 393 | 37 | 0.094 | 0 |
| PDE4A | PDE4A | P27815 | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | chr19 | GO:0004114 | Not Cancer Driver | No | 123 | 0.139 | 559 | 67 | 0.12 | 0 |
| PDE4B | PDE4B | Q07343 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | chr1 | GO:0004114 | Not Cancer Driver | No | 119 | 0.162 | 363 | 42 | 0.116 | 0 |
| PDE4C | PDE4C | Q08493 | cAMP-specific 3',5'-cyclic phosphodiesterase 4C | chr19 | GO:0004114 | Not Cancer Driver | No | 122 | 0.171 | 362 | 61 | 0.169 | 0 |
| PDE4D | PDE4D | Q08499 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | chr5 | GO:0004114 | Not Cancer Driver | No | 86 | 0.106 | 464 | 54 | 0.116 | 12 |
| PDE5A | PDE5A | O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | chr4 | GO:0004114 | Not Cancer Driver | No | 113 | 0.129 | 163 | 23 | 0.141 | 0 |
| PDE6A | PDE6A | P16499 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | chr5 | GO:0004114 | Not Cancer Driver | No | 139 | 0.162 | 91 | 12 | 0.132 | 5 |
| PDE6B | PDE6B | P35913 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | chr4 | GO:0004114 | Not Cancer Driver | No | 144 | 0.169 | 44 | 9 | 0.205 | 13 |
| PDE6C | PDE6C | P51160 | Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' | chr10 | GO:0004114 | Not Cancer Driver | No | 127 | 0.148 | 87 | 17 | 0.195 | 8 |
| PDE7A | PDE7A | Q13946 | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | chr8 | GO:0004114 | Not Cancer Driver | No | 49 | 0.102 | 30 | 7 | 0.233 | 0 |
| PDE7B | PDE7B | Q9NP56 | cAMP-specific 3',5'-cyclic phosphodiesterase 7B | chr6 | GO:0004114 | Not Cancer Driver | No | 74 | 0.164 | 47 | 7 | 0.149 | 0 |
| PDE8A_ENST00000394553 | PDE8A | O60658 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | chr15 | GO:0004114 | Not Cancer Driver | No | 78 | 0.094 | 187 | 17 | 0.091 | 0 |
| PDE8B | PDE8B | O95263 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B | chr5 | GO:0004114 | Not Cancer Driver | No | 144 | 0.163 | 208 | 19 | 0.091 | 1 |
| PDE9A | PDE9A | O76083 | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | chr21 | GO:0004114 | Not Cancer Driver | No | 91 | 0.153 | 160 | 34 | 0.212 | 0 |