Total number of protein in "GO:0003073" GO term: 41
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0003073 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ACE2 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | GO:0003073 | Not Cancer Driver | No | 104 | 0.129 | 68 | 5 | 0.074 | 0 |
| ADAMTS16 | ADAMTS16 | Q8TE57 | A disintegrin and metalloproteinase with thrombospondin motifs 16 | chr5 | GO:0003073 | Not Cancer Driver | No | 383 | 0.313 | 179 | 59 | 0.33 | 0 |
| ADM | ADM | P35318 | Pro-adrenomedullin | chr11 | GO:0003073 | Not Cancer Driver | No | 20 | 0.108 | 113 | 13 | 0.115 | 0 |
| ADM2_ENST00000395737 | ADM2 | Q7Z4H4 | Protein ADM2 | chr22 | GO:0003073 | Not Cancer Driver | No | 14 | 0.095 | 113 | 11 | 0.097 | 0 |
| ADM5 | ADM5 | C9JUS6 | Putative adrenomedullin-5-like protein | chr19 | GO:0003073 | Not Cancer Driver | No | 6 | 0.039 | 35 | 4 | 0.114 | 0 |
| AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0003073 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
| AGTR1_ENST00000349243 | AGTR1 | P30556 | Type-1 angiotensin II receptor | chr3 | GO:0003073 | Not Cancer Driver | No | 95 | 0.265 | 0 | 0 | 0.0 | 1 |
| AGTR2 | AGTR2 | P50052 | Type-2 angiotensin II receptor | chrX | GO:0003073 | Not Cancer Driver | No | 98 | 0.27 | 0 | 0 | 0.0 | 0 |
| AR | AR | P10275 | Androgen receptor | chrX | GO:0003073 | Census, Compendium | Yes | 196 | 0.213 | 443 | 88 | 0.199 | 169 |
| AVPR1A | AVPR1A | P37288 | Vasopressin V1a receptor | chr12 | GO:0003073 | Not Cancer Driver | No | 105 | 0.251 | 68 | 25 | 0.368 | 0 |
| AVPR1B | AVPR1B | P47901 | Vasopressin V1b receptor | chr1 | GO:0003073 | Not Cancer Driver | No | 83 | 0.196 | 51 | 5 | 0.098 | 0 |
| AVPR2_ENST00000337474 | AVPR2 | P30518 | Vasopressin V2 receptor | chrX | GO:0003073 | Not Cancer Driver | No | 58 | 0.156 | 56 | 7 | 0.125 | 84 |
| CORIN | CORIN | Q9Y5Q5 | Atrial natriuretic peptide-converting enzyme | chr4 | GO:0003073 | Not Cancer Driver | No | 208 | 0.2 | 60 | 13 | 0.217 | 2 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | GO:0003073 | Not Cancer Driver | No | 26 | 0.133 | 66 | 2 | 0.03 | 12 |
| CYP11B2 | CYP11B2 | P19099 | Cytochrome P450 11B2, mitochondrial | chr8 | GO:0003073 | Not Cancer Driver | No | 148 | 0.294 | 6 | 0 | 0.0 | 6 |
| DDAH1 | DDAH1 | O94760 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | chr1 | GO:0003073 | Not Cancer Driver | No | 28 | 0.098 | 44 | 3 | 0.068 | 0 |
| DRD5 | DRD5 | P21918 | D(1B) dopamine receptor | chr4 | GO:0003073 | Not Cancer Driver | No | 172 | 0.361 | 29 | 18 | 0.621 | 0 |
| ECE1 | ECE1 | P42892 | Endothelin-converting enzyme 1 | chr1 | GO:0003073 | Not Cancer Driver | No | 118 | 0.153 | 99 | 26 | 0.263 | 1 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0003073 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EDN2 | EDN2 | P20800 | Endothelin-2 | chr1 | GO:0003073 | Not Cancer Driver | No | 21 | 0.118 | 87 | 13 | 0.149 | 0 |
| EDN3_ENST00000371028 | EDN3 | P14138 | Endothelin-3 | chr20 | GO:0003073 | Not Cancer Driver | No | 69 | 0.29 | 140 | 44 | 0.314 | 3 |
| ENPEP | ENPEP | Q07075 | Glutamyl aminopeptidase | chr4 | GO:0003073 | Compendium | Yes | 235 | 0.246 | 130 | 44 | 0.338 | 0 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0003073 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0003073 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
| GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0003073 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
| HSD11B2 | HSD11B2 | P80365 | 11-beta-hydroxysteroid dehydrogenase type 2 | chr16 | GO:0003073 | Not Cancer Driver | No | 27 | 0.067 | 30 | 0 | 0.0 | 14 |
| KLK1 | KLK1 | P06870 | Kallikrein-1 | chr19 | GO:0003073 | Not Cancer Driver | No | 49 | 0.187 | 22 | 3 | 0.136 | 0 |
| KLK2 | KLK2 | P20151 | Kallikrein-2 | chr19 | GO:0003073 | Census | Yes | 53 | 0.203 | 11 | 3 | 0.273 | 0 |
| KLK3 | KLK3 | P07288 | Prostate-specific antigen | chr19 | GO:0003073 | Not Cancer Driver | No | 68 | 0.261 | 6 | 1 | 0.167 | 0 |
| NCALD | NCALD | P61601 | Neurocalcin-delta | chr8 | GO:0003073 | Not Cancer Driver | No | 37 | 0.192 | 34 | 4 | 0.118 | 0 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0003073 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| NOX1 | NOX1 | Q9Y5S8 | NADPH oxidase 1 | chrX | GO:0003073 | Not Cancer Driver | No | 101 | 0.179 | 18 | 8 | 0.444 | 0 |
| OR51E2_ENST00000641638 | OR51E2 | Q9H255 | Olfactory receptor 51E2 | chr11 | GO:0003073 | Not Cancer Driver | No | 108 | 0.338 | 0 | 0 | 0.0 | 0 |
| OXTR | OXTR | P30559 | Oxytocin receptor | chr3 | GO:0003073 | Not Cancer Driver | No | 46 | 0.118 | 18 | 0 | 0.0 | 0 |
| PLCB3 | PLCB3 | Q01970 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | chr11 | GO:0003073 | Not Cancer Driver | No | 144 | 0.117 | 595 | 68 | 0.114 | 1 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0003073 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RPS6KA2_ENST00000265678 | RPS6KA2 | Q15349 | Ribosomal protein S6 kinase alpha-2 | chr6 | GO:0003073 | Not Cancer Driver | No | 133 | 0.181 | 91 | 15 | 0.165 | 0 |
| SERPINF2_ENST00000382061 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0003073 | Not Cancer Driver | No | 62 | 0.126 | 112 | 21 | 0.188 | 1 |
| SLC2A5 | SLC2A5 | P22732 | Solute carrier family 2, facilitated glucose transporter member 5 | chr1 | GO:0003073 | Not Cancer Driver | No | 73 | 0.146 | 12 | 4 | 0.333 | 0 |
| SLC4A5_ENST00000377634 | SLC4A5 | Q9BY07 | Electrogenic sodium bicarbonate cotransporter 4 | chr2 | GO:0003073 | Not Cancer Driver | No | 167 | 0.147 | 353 | 46 | 0.13 | 0 |