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Total number of protein in "GO:0003006" GO term:  432

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACRBP ACRBP Q8NEB7 Acrosin-binding protein chr12 GO:0003006 Not Cancer Driver No 81 0.149 200 27 0.135 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0003006 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACTL7A ACTL7A Q9Y615 Actin-like protein 7A chr9 GO:0003006 Not Cancer Driver No 62 0.143 118 17 0.144 0
ACTL9_ENST00000612068 ACTL9 Q8TC94 Actin-like protein 9 chr19 GO:0003006 Not Cancer Driver No 119 0.286 101 19 0.188 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0003006 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM19_ENST00000517905 ADAM19 Q9H013 Disintegrin and metalloproteinase domain-containing protein 19 chr5 GO:0003006 Not Cancer Driver No 172 0.18 370 77 0.208 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0003006 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0003006 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0003006 Not Cancer Driver No 20 0.108 113 13 0.115 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0003006 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0003006 Not Cancer Driver No 55 0.141 77 11 0.143 0
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0003006 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0003006 Not Cancer Driver No 80 0.153 184 39 0.212 113
AMH AMH P03971 Muellerian-inhibiting factor chr19 GO:0003006 Not Cancer Driver No 19 0.034 207 4 0.019 9
AMHR2 AMHR2 Q16671 Anti-Muellerian hormone type-2 receptor chr12 GO:0003006 Not Cancer Driver No 77 0.134 117 7 0.06 8
ANG ANG P03950 Angiogenin chr14 GO:0003006 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0003006 Not Cancer Driver No 59 0.171 61 12 0.197 0
APELA APELA P0DMC3 Apelin receptor early endogenous ligand chr4 GO:0003006 Not Cancer Driver No 1 0.019 0 0 0.0 0
AR AR P10275 Androgen receptor chrX GO:0003006 Census, Compendium Yes 196 0.213 443 88 0.199 169
AREG AREG P15514 Amphiregulin chr4 GO:0003006 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARID4A ARID4A P29374 AT-rich interactive domain-containing protein 4A chr14 GO:0003006 Not Cancer Driver No 151 0.12 978 123 0.126 0
ARID4B ARID4B Q4LE39 AT-rich interactive domain-containing protein 4B chr1 GO:0003006 Not Cancer Driver No 143 0.109 1005 118 0.117 0
ARID5B ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 GO:0003006 Not Cancer Driver No 162 0.136 769 95 0.124 0
ARMC12_ENST00000373866 ARMC12 Q5T9G4 Armadillo repeat-containing protein 12 chr6 GO:0003006 Not Cancer Driver No 58 0.171 8 0 0.0 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0003006 Census Yes 77 0.098 511 56 0.11 0
ASB1 ASB1 Q9Y576 Ankyrin repeat and SOCS box protein 1 chr2 GO:0003006 Not Cancer Driver No 49 0.146 37 2 0.054 0
ASCL2 ASCL2 Q99929 Achaete-scute homolog 2 chr11 GO:0003006 Not Cancer Driver No 2 0.01 166 1 0.006 0
ASH1L_ENST00000368346 ASH1L Q9NR48 Histone-lysine N-methyltransferase ASH1L chr1 GO:0003006 Not Cancer Driver No 415 0.14 1858 256 0.138 1
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0003006 Not Cancer Driver No 554 0.159 424 67 0.158 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0003006 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0003006 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKC AURKC Q9UQB9 Aurora kinase C chr19 GO:0003006 Not Cancer Driver No 70 0.227 43 5 0.116 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0003006 Not Cancer Driver No 168 0.188 341 64 0.188 0
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0003006 Not Cancer Driver No 38 0.095 129 13 0.101 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0003006 Not Cancer Driver No 38 0.18 58 9 0.155 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 GO:0003006 Not Cancer Driver No 39 0.172 227 39 0.172 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0003006 Census Yes 30 0.156 39 2 0.051 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0003006 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0003006 Census, Compendium Yes 24 0.1 72 5 0.069 0
BHMG1 MEIOSIN C9JSJ3 Meiosis initiator protein chr19 GO:0003006 Not Cancer Driver No 0 0.0 498 0 0.0 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0003006 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC6 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 GO:0003006 Census, Compendium Yes 640 0.132 1312 170 0.13 0
BMP15 BMP15 O95972 Bone morphogenetic protein 15 chrX GO:0003006 Not Cancer Driver No 91 0.232 81 15 0.185 13
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0003006 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0003006 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0003006 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0003006 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0003006 Compendium Yes 141 0.136 601 70 0.116 19
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 GO:0003006 Not Cancer Driver No 309 0.101 2187 218 0.1 2
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0003006 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0003006 Census Yes 174 0.139 397 59 0.149 6
BSG BSG P35613 Basigin chr19 GO:0003006 Not Cancer Driver No 43 0.112 123 17 0.138 0
C14orf39 SIX6OS1 Q8N1H7 Protein SIX6OS1 chr14 GO:0003006 Not Cancer Driver No 128 0.218 326 76 0.233 0
C3 C3 P01024 Complement C3 chr19 GO:0003006 Not Cancer Driver No 337 0.203 287 50 0.174 12
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0003006 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0003006 Census, Compendium Yes 142 0.296 106 12 0.113 1
CBX2 CBX2 Q14781 Chromobox protein homolog 2 chr17 GO:0003006 Not Cancer Driver No 56 0.105 487 53 0.109 2
CBX7 CBX7 O95931 Chromobox protein homolog 7 chr22 GO:0003006 Not Cancer Driver No 40 0.159 175 34 0.194 0
CCDC134 CCDC134 Q9H6E4 Coiled-coil domain-containing protein 134 chr22 GO:0003006 Not Cancer Driver No 24 0.105 43 3 0.07 0
CCDC136 CCDC136 Q96JN2 Coiled-coil domain-containing protein 136 chr7 GO:0003006 Not Cancer Driver No 150 0.13 818 114 0.139 0
CCDC155 KASH5 Q8N6L0 Protein KASH5 chr19 GO:0003006 Not Cancer Driver No 88 0.157 401 70 0.175 0
CCDC36_ENST00000452691 IHO1 Q8IYA8 Interactor of HORMAD1 protein 1 chr3 GO:0003006 Not Cancer Driver No 83 0.14 355 43 0.121 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0003006 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0003006 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCNF CCNF P41002 Cyclin-F chr16 GO:0003006 Not Cancer Driver No 106 0.135 221 23 0.104 3
CDC25B CDC25B P30305 M-phase inducer phosphatase 2 chr20 GO:0003006 Not Cancer Driver No 80 0.138 328 43 0.131 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0003006 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0003006 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDX2 CDX2 Q99626 Homeobox protein CDX-2 chr13 GO:0003006 Census, Compendium Yes 39 0.125 271 35 0.129 0
CDX4 CDX4 O14627 Homeobox protein CDX-4 chrX GO:0003006 Not Cancer Driver No 86 0.303 188 54 0.287 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0003006 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0003006 Not Cancer Driver No 3 0.009 276 2 0.007 0
CFAP58 CFAP58 Q5T655 Cilia- and flagella-associated protein 58 chr10 GO:0003006 Not Cancer Driver No 207 0.237 392 81 0.207 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0003006 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0003006 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0003006 Not Cancer Driver No 23 0.085 230 18 0.078 0
COL9A3 COL9A3 Q14050 Collagen alpha-3(IX) chain chr20 GO:0003006 Not Cancer Driver No 118 0.173 684 118 0.173 1
CRIP1_ENST00000409393 CRIP1 P50238 Cysteine-rich protein 1 chr14 GO:0003006 Not Cancer Driver No 6 0.078 8 1 0.125 0
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0003006 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0003006 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSMD1 CSMD1 Q96PZ7 CUB and sushi domain-containing protein 1 chr8 GO:0003006 Not Cancer Driver No 1236 0.347 234 76 0.325 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0003006 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0003006 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTSB CTSB P07858 Cathepsin B chr8 GO:0003006 Not Cancer Driver No 41 0.121 7 2 0.286 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:0003006 Not Cancer Driver No 188 0.111 372 41 0.11 3
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0003006 Not Cancer Driver No 91 0.181 2 1 0.5 5
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0003006 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP7B1 CYP7B1 O75881 Cytochrome P450 7B1 chr8 GO:0003006 Not Cancer Driver No 133 0.263 0 0 0.0 11
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:0003006 Not Cancer Driver No 157 0.207 641 134 0.209 0
DACH2 DACH2 Q96NX9 Dachshund homolog 2 chrX GO:0003006 Not Cancer Driver No 201 0.336 443 163 0.368 0
DAZAP1 DAZAP1 Q96EP5 DAZ-associated protein 1 chr19 GO:0003006 Compendium Yes 53 0.13 327 45 0.138 0
DCANP1 DCANP1 Q8TF63 Dendritic cell nuclear protein 1 chr5 GO:0003006 Not Cancer Driver No 44 0.18 159 35 0.22 0
DDX20 DDX20 Q9UHI6 Probable ATP-dependent RNA helicase DDX20 chr1 GO:0003006 Not Cancer Driver No 89 0.108 299 33 0.11 0
DEDD_ENST00000545495 DEDD O75618 Death effector domain-containing protein chr1 GO:0003006 Not Cancer Driver No 36 0.113 90 7 0.078 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0003006 Not Cancer Driver No 55 0.107 0 0 0.0 6
DHH DHH O43323 Desert hedgehog protein chr12 GO:0003006 Not Cancer Driver No 36 0.091 57 7 0.123 1
DIAPH2 DIAPH2 O60879 Protein diaphanous homolog 2 chrX GO:0003006 Not Cancer Driver No 195 0.177 460 95 0.207 0
DLX3 DLX3 O60479 Homeobox protein DLX-3 chr17 GO:0003006 Not Cancer Driver No 46 0.16 201 28 0.139 0
DMC1 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 GO:0003006 Not Cancer Driver No 39 0.115 49 5 0.102 0
DMRT1 DMRT1 Q9Y5R6 Doublesex- and mab-3-related transcription factor 1 chr9 GO:0003006 Not Cancer Driver No 60 0.161 282 47 0.167 0
DMRTA1 DMRTA1 Q5VZB9 Doublesex- and mab-3-related transcription factor A1 chr9 GO:0003006 Not Cancer Driver No 50 0.099 276 25 0.091 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 GO:0003006 Not Cancer Driver No 33 0.101 198 17 0.086 3
DNAJC19 DNAJC19 Q96DA6 Mitochondrial import inner membrane translocase subunit TIM14 chr3 GO:0003006 Not Cancer Driver No 19 0.164 27 6 0.222 0
DZIP1_ENST00000376829 DZIP1 Q86YF9 Cilium assembly protein DZIP1 chr13 GO:0003006 Not Cancer Driver No 143 0.165 523 92 0.176 2
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0003006 Not Cancer Driver No 122 0.134 554 70 0.126 0
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 GO:0003006 Not Cancer Driver No 132 0.152 582 85 0.146 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0003006 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 GO:0003006 Not Cancer Driver No 40 0.114 83 11 0.133 9
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 GO:0003006 Not Cancer Driver No 57 0.109 212 29 0.137 7
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 GO:0003006 Not Cancer Driver No 76 0.105 179 16 0.089 29
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0003006 Not Cancer Driver No 82 0.12 436 50 0.115 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0003006 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPOR EPOR P19235 Erythropoietin receptor chr19 GO:0003006 Not Cancer Driver No 41 0.081 120 11 0.092 1
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0003006 Not Cancer Driver No 42 0.141 105 14 0.133 1
EREG EREG O14944 Proepiregulin chr4 GO:0003006 Not Cancer Driver No 26 0.154 10 3 0.3 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0003006 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0003006 Not Cancer Driver No 90 0.208 35 7 0.2 4
ETNK2_ENST00000367202 ETNK2 Q9NVF9 Ethanolamine kinase 2 chr1 GO:0003006 Not Cancer Driver No 46 0.119 38 34 0.895 0
ETV2_ENST00000403402 ETV2 O00321 ETS translocation variant 2 chr19 GO:0003006 Not Cancer Driver No 23 0.067 227 15 0.066 0
FABP9 FABP9 Q0Z7S8 Fatty acid-binding protein 9 chr8 GO:0003006 Not Cancer Driver No 33 0.25 10 5 0.5 0
FANCA FANCA O15360 Fanconi anemia group A protein chr16 GO:0003006 Census, Compendium Yes 160 0.11 154 15 0.097 27
FANCG FANCG O15287 Fanconi anemia group G protein chr9 GO:0003006 Census Yes 64 0.103 48 3 0.062 1
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0003006 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0003006 Not Cancer Driver No 68 0.114 120 4 0.033 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0003006 Not Cancer Driver No 69 0.11 33 3 0.091 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0003006 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0003006 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0003006 Not Cancer Driver No 41 0.197 43 10 0.233 1
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0003006 Census, Compendium Yes 238 0.29 228 44 0.193 72
FIGLA FIGLA Q6QHK4 Factor in the germline alpha chr2 GO:0003006 Not Cancer Driver No 22 0.1 154 17 0.11 0
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 GO:0003006 Not Cancer Driver No 46 0.1 134 12 0.09 0
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:0003006 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FNDC3A_ENST00000492622 FNDC3A Q9Y2H6 Fibronectin type-III domain-containing protein 3A chr13 GO:0003006 Not Cancer Driver No 121 0.101 499 45 0.09 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0003006 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0003006 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0003006 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXF2 FOXF2 Q12947 Forkhead box protein F2 chr6 GO:0003006 Not Cancer Driver No 44 0.099 277 10 0.036 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0003006 Census, Compendium Yes 39 0.104 257 20 0.078 26
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0003006 Census, Compendium Yes 70 0.104 595 68 0.114 0
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0003006 Not Cancer Driver No 69 0.136 415 58 0.14 0
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0003006 Not Cancer Driver No 226 0.325 28 11 0.393 16
FST FST P19883 Follistatin chr5 GO:0003006 Not Cancer Driver No 50 0.145 20 7 0.35 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0003006 Not Cancer Driver No 45 0.077 58 4 0.069 0
GAS2 GAS2 O43903 Growth arrest-specific protein 2 chr11 GO:0003006 Not Cancer Driver No 73 0.233 92 16 0.174 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0003006 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0003006 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0003006 Census, Compendium Yes 111 0.251 364 87 0.239 2
GCM1 GCM1 Q9NP62 Chorion-specific transcription factor GCMa chr6 GO:0003006 Not Cancer Driver No 78 0.179 194 36 0.186 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0003006 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0003006 Not Cancer Driver No 85 0.232 4 0 0.0 2
GJB1_ENST00000647424 GJB1 P08034 Gap junction beta-1 protein chrX GO:0003006 Not Cancer Driver No 34 0.12 23 7 0.304 189
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0003006 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJB3 GJB3 O75712 Gap junction beta-3 protein chr1 GO:0003006 Not Cancer Driver No 48 0.178 13 0 0.0 6
GJB5 GJB5 O95377 Gap junction beta-5 protein chr1 GO:0003006 Not Cancer Driver No 38 0.139 8 5 0.625 0
GK2 GK2 Q14410 Glycerol kinase 2 chr4 GO:0003006 Not Cancer Driver No 175 0.316 14 3 0.214 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0003006 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0003006 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPR149 GPR149 Q86SP6 Probable G-protein coupled receptor 149 chr3 GO:0003006 Not Cancer Driver No 180 0.246 286 74 0.259 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0003006 Not Cancer Driver No 28 0.129 10 1 0.1 0
GREB1L GREB1L Q9C091 GREB1-like protein chr18 GO:0003006 Not Cancer Driver No 87 0.045 480 22 0.046 25
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0003006 Not Cancer Driver No 95 0.152 258 43 0.167 2
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0003006 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0003006 Not Cancer Driver No 28 0.206 51 14 0.275 3
HAND1 HAND1 O96004 Heart- and neural crest derivatives-expressed protein 1 chr5 GO:0003006 Not Cancer Driver No 35 0.163 166 29 0.175 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 GO:0003006 Not Cancer Driver No 274 0.105 991 108 0.109 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0003006 Not Cancer Driver No 37 0.132 226 32 0.142 0
HESX1 HESX1 Q9UBX0 Homeobox expressed in ES cells 1 chr3 GO:0003006 Not Cancer Driver No 32 0.173 59 9 0.153 6
HEXB HEXB P07686 Beta-hexosaminidase subunit beta chr5 GO:0003006 Not Cancer Driver No 45 0.081 0 0 0.0 9
HEY1_ENST00000354724 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:0003006 Census Yes 33 0.109 172 15 0.087 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0003006 Not Cancer Driver No 64 0.19 179 26 0.145 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0003006 Census Yes 118 0.143 435 51 0.117 0
HORMAD1 HORMAD1 Q86X24 HORMA domain-containing protein 1 chr1 GO:0003006 Not Cancer Driver No 76 0.193 178 31 0.174 0
HOXA10 HOXA10 P31260 Homeobox protein Hox-A10 chr7 GO:0003006 Not Cancer Driver No 35 0.085 339 25 0.074 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0003006 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 GO:0003006 Census Yes 37 0.095 171 22 0.129 4
HOXB13 HOXB13 Q92826 Homeobox protein Hox-B13 chr17 GO:0003006 Not Cancer Driver No 61 0.215 179 37 0.207 1
HOXD13 HOXD13 P35453 Homeobox protein Hox-D13 chr2 GO:0003006 Census, Compendium Yes 43 0.125 113 12 0.106 9
HS6ST1 HS6ST1 O60243 Heparan-sulfate 6-O-sulfotransferase 1 chr2 GO:0003006 Not Cancer Driver No 60 0.146 66 14 0.212 6
HSD17B2 HSD17B2 P37059 17-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0003006 Not Cancer Driver No 55 0.142 6 1 0.167 0
HSD17B3 HSD17B3 P37058 17-beta-hydroxysteroid dehydrogenase type 3 chr9 GO:0003006 Not Cancer Driver No 42 0.135 0 0 0.0 15
HSD17B4_ENST00000256216 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 GO:0003006 Not Cancer Driver No 99 0.135 82 12 0.146 4
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0003006 Census, Compendium Yes 100 0.138 254 43 0.169 0
HTRA1 HTRA1 Q92743 Serine protease HTRA1 chr10 GO:0003006 Not Cancer Driver No 77 0.16 40 9 0.225 11
HYAL3 HYAL3 O43820 Hyaluronidase-3 chr3 GO:0003006 Not Cancer Driver No 48 0.115 10 0 0.0 0
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0003006 Not Cancer Driver No 4 0.025 71 1 0.014 0
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 GO:0003006 Census, Compendium Yes 553 1.336 37 3 0.081 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0003006 Not Cancer Driver No 39 0.217 44 12 0.273 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0003006 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0003006 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0003006 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0003006 Not Cancer Driver No 39 0.145 16 3 0.188 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 GO:0003006 Not Cancer Driver No 36 0.206 29 7 0.241 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0003006 Not Cancer Driver No 33 0.118 169 26 0.154 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0003006 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0003006 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0003006 Not Cancer Driver No 61 0.15 98 5 0.051 0
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:0003006 Not Cancer Driver No 18 0.137 34 12 0.353 3
INSR INSR P06213 Insulin receptor chr19 GO:0003006 Not Cancer Driver No 190 0.137 280 57 0.204 64
INSRR INSRR P14616 Insulin receptor-related protein chr1 GO:0003006 Not Cancer Driver No 262 0.202 228 37 0.162 0
IRF2BPL IRF2BPL Q9H1B7 Probable E3 ubiquitin-protein ligase IRF2BPL chr14 GO:0003006 Not Cancer Driver No 61 0.077 526 31 0.059 1
IRX5 IRX5 P78411 Iroquois-class homeodomain protein IRX-5 chr16 GO:0003006 Not Cancer Driver No 85 0.176 359 62 0.173 2
ITGB8 ITGB8 P26012 Integrin beta-8 chr7 GO:0003006 Not Cancer Driver No 126 0.164 26 3 0.115 0
JUNB JUNB P17275 Transcription factor JunB chr19 GO:0003006 Not Cancer Driver No 20 0.058 305 16 0.052 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0003006 Not Cancer Driver No 219 0.142 388 58 0.149 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0003006 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0003006 Not Cancer Driver No 114 0.127 405 60 0.148 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0003006 Census, Compendium Yes 226 0.232 83 33 0.398 21
KITLG KITLG P21583 Kit ligand chr12 GO:0003006 Not Cancer Driver No 48 0.176 61 9 0.148 1
KLC3 KLC3 Q6P597 Kinesin light chain 3 chr19 GO:0003006 Not Cancer Driver No 52 0.103 338 32 0.095 0
KLHL10 KLHL10 Q6JEL2 Kelch-like protein 10 chr17 GO:0003006 Not Cancer Driver No 77 0.127 24 2 0.083 2
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 GO:0003006 Census, Compendium Yes 773 0.14 4386 552 0.126 13
KNL1 KNL1 Q8NG31 Kinetochore scaffold 1 chr15 GO:0003006 Census Yes 272 0.116 1265 135 0.107 1
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 GO:0003006 Not Cancer Driver No 57 0.142 165 19 0.115 0
LDOC1 LDOC1 O95751 Protein LDOC1 chrX GO:0003006 Not Cancer Driver No 48 0.329 23 10 0.435 0
LEP LEP P41159 Leptin chr7 GO:0003006 Not Cancer Driver No 29 0.174 0 0 0.0 2
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0003006 Not Cancer Driver No 37 0.098 65 1 0.015 1
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0003006 Not Cancer Driver No 108 0.114 16 3 0.188 0
LGR5 LGR5 O75473 Leucine-rich repeat-containing G-protein coupled receptor 5 chr12 GO:0003006 Not Cancer Driver No 124 0.137 13 2 0.154 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0003006 Not Cancer Driver No 181 0.259 12 8 0.667 25
LHFPL2_ENST00000515007 LHFPL2 Q6ZUX7 LHFPL tetraspan subfamily member 2 protein chr5 GO:0003006 Not Cancer Driver No 14 0.061 9 0 0.0 0
LHX3_ENST00000371748 LHX3 Q9UBR4 LIM/homeobox protein Lhx3 chr9 GO:0003006 Not Cancer Driver No 38 0.096 232 14 0.06 2
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 GO:0003006 Not Cancer Driver No 75 0.192 219 45 0.205 4
LHX8 LHX8 Q68G74 LIM/homeobox protein Lhx8 chr1 GO:0003006 Not Cancer Driver No 93 0.261 157 47 0.299 0
LHX9 LHX9 Q9NQ69 LIM/homeobox protein Lhx9 chr1 GO:0003006 Not Cancer Driver No 97 0.244 191 46 0.241 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0003006 Not Cancer Driver No 25 0.124 0 0 0.0 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0003006 Not Cancer Driver No 998 0.214 209 40 0.191 1
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0003006 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0003006 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0003006 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0003006 Census, Compendium Yes 62 0.172 2 0 0.0 7
MARF1 MARF1 Q9Y4F3 Meiosis regulator and mRNA stability factor 1 chr16 GO:0003006 Not Cancer Driver No 199 0.114 524 73 0.139 0
MDFI MDFI Q99750 MyoD family inhibitor chr6 GO:0003006 Not Cancer Driver No 25 0.102 152 15 0.099 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0003006 Not Cancer Driver No 15 0.105 20 2 0.1 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0003006 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEI4 MEI4 A8MW99 Meiosis-specific protein MEI4 chr6 GO:0003006 Not Cancer Driver No 0 0.0 69 0 0.0 0
MEIOC MEIOC A2RUB1 Meiosis-specific coiled-coil domain-containing protein MEIOC chr17 GO:0003006 Not Cancer Driver No 92 0.097 529 54 0.102 0
MEN1 MEN1 O00255 Menin chr11 GO:0003006 Census, Compendium Yes 73 0.119 228 15 0.066 90
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0003006 Not Cancer Driver No 175 0.175 159 31 0.195 3
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0003006 Not Cancer Driver No 74 0.128 274 29 0.106 0
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 GO:0003006 Not Cancer Driver No 56 0.098 6 1 0.167 22
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0003006 Census Yes 92 0.122 208 22 0.106 85
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0003006 Not Cancer Driver No 189 0.252 40 17 0.425 4
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0003006 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP19 MMP19 Q99542 Matrix metalloproteinase-19 chr12 GO:0003006 Not Cancer Driver No 94 0.185 98 20 0.204 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0003006 Not Cancer Driver No 123 0.186 29 6 0.207 2
MSH4 MSH4 O15457 MutS protein homolog 4 chr1 GO:0003006 Not Cancer Driver No 199 0.213 196 42 0.214 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0003006 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0003006 Not Cancer Driver No 284 0.303 853 263 0.308 0
NANOS1 NANOS1 Q8WY41 Nanos homolog 1 chr10 GO:0003006 Not Cancer Driver No 7 0.024 169 2 0.012 0
NANOS2 NANOS2 P60321 Nanos homolog 2 chr19 GO:0003006 Not Cancer Driver No 29 0.21 50 11 0.22 0
NANOS3_ENST00000397555 NANOS3 P60323 Nanos homolog 3 chr19 GO:0003006 Not Cancer Driver No 31 0.179 117 25 0.214 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0003006 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NDP_ENST00000642620 NDP Q00604 Norrin chrX GO:0003006 Not Cancer Driver No 14 0.105 0 0 0.0 60
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0003006 Not Cancer Driver No 63 0.117 296 29 0.098 0
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0003006 Not Cancer Driver No 27 0.114 178 18 0.101 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0003006 Compendium Yes 353 0.126 1528 184 0.12 37
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0003006 Not Cancer Driver No 35 0.15 171 16 0.094 0
NOBOX NOBOX O60393 Homeobox protein NOBOX chr7 GO:0003006 Not Cancer Driver No 127 0.184 615 110 0.179 3
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0003006 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0003006 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0003006 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0003006 Census, Compendium Yes 282 0.114 630 77 0.122 1
NPM2_ENST00000518119 NPM2 Q86SE8 Nucleoplasmin-2 chr8 GO:0003006 Not Cancer Driver No 25 0.117 165 21 0.127 0
NR0B1 NR0B1 P51843 Nuclear receptor subfamily 0 group B member 1 chrX GO:0003006 Not Cancer Driver No 106 0.226 97 18 0.186 18
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0003006 Not Cancer Driver No 66 0.159 101 1 0.01 5
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 GO:0003006 Not Cancer Driver No 60 0.13 133 29 0.218 24
NSDHL NSDHL Q15738 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating chrX GO:0003006 Not Cancer Driver No 60 0.161 39 6 0.154 3
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0003006 Census, Compendium Yes 168 0.211 57 8 0.14 25
NUP107 NUP107 P57740 Nuclear pore complex protein Nup107 chr12 GO:0003006 Not Cancer Driver No 127 0.137 183 26 0.142 5
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0003006 Not Cancer Driver No 57 0.214 67 17 0.254 0
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0003006 Not Cancer Driver No 29 0.105 139 8 0.058 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0003006 Not Cancer Driver No 42 0.102 82 11 0.134 7
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0003006 Not Cancer Driver No 54 0.127 45 7 0.156 2
PAQR5 PAQR5 Q9NXK6 Membrane progestin receptor gamma chr15 GO:0003006 Not Cancer Driver No 44 0.133 2 0 0.0 0
PAQR7 PAQR7 Q86WK9 Membrane progestin receptor alpha chr1 GO:0003006 Not Cancer Driver No 32 0.092 0 0 0.0 0
PAQR8 PAQR8 Q8TEZ7 Membrane progestin receptor beta chr6 GO:0003006 Not Cancer Driver No 45 0.127 0 0 0.0 0
PCDH12 PCDH12 Q9NPG4 Protocadherin-12 chr5 GO:0003006 Not Cancer Driver No 158 0.133 582 80 0.137 0
PCYT1B PCYT1B Q9Y5K3 Choline-phosphate cytidylyltransferase B chrX GO:0003006 Not Cancer Driver No 60 0.163 171 17 0.099 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0003006 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0003006 Census Yes 37 0.154 99 22 0.222 2
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0003006 Census, Compendium Yes 290 0.266 173 45 0.26 2
PGR PGR P06401 Progesterone receptor chr11 GO:0003006 Not Cancer Driver No 161 0.173 480 55 0.115 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0003006 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHLDA2_ENST00000645523 PHLDA2 Q53GA4 Pleckstrin homology-like domain family A member 2 chr11 GO:0003006 Not Cancer Driver No 12 0.079 58 2 0.034 0
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0003006 Not Cancer Driver No 138 0.142 232 38 0.164 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0003006 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0003006 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0003006 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLAC1 PLAC1 Q9HBJ0 Placenta-specific protein 1 chrX GO:0003006 Not Cancer Driver No 23 0.108 37 4 0.108 0
PLAG1_ENST00000429357 PLAG1 Q6DJT9 Zinc finger protein PLAG1 chr8 GO:0003006 Census, Compendium Yes 108 0.216 209 48 0.23 0
PLCD3 PLCD3 Q8N3E9 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 chr17 GO:0003006 Not Cancer Driver No 61 0.077 229 22 0.096 0
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0003006 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLG PLG P00747 Plasminogen chr6 GO:0003006 Not Cancer Driver No 242 0.299 230 64 0.278 9
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 GO:0003006 Not Cancer Driver No 102 0.105 451 45 0.1 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0003006 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0003006 Census Yes 72 0.143 44 4 0.091 3
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0003006 Not Cancer Driver No 47 0.058 695 35 0.05 0
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0003006 Census, Compendium Yes 145 0.176 337 66 0.196 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0003006 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0003006 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRLR PRLR P16471 Prolactin receptor chr5 GO:0003006 Not Cancer Driver No 154 0.248 282 70 0.248 2
PSAP PSAP P07602 Prosaposin chr10 GO:0003006 Not Cancer Driver No 59 0.113 28 2 0.071 8
PSAPL1 PSAPL1 Q6NUJ1 Proactivator polypeptide-like 1 chr4 GO:0003006 Not Cancer Driver No 62 0.119 7 1 0.143 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0003006 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0003006 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0003006 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0003006 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0003006 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0003006 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTN PTN P21246 Pleiotrophin chr7 GO:0003006 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0003006 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0003006 Census, Compendium Yes 73 0.123 192 25 0.13 0
RAB13 RAB13 P51153 Ras-related protein Rab-13 chr1 GO:0003006 Not Cancer Driver No 19 0.094 40 0 0.0 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0003006 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0003006 Not Cancer Driver No 82 0.181 164 24 0.146 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0003006 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 GO:0003006 Not Cancer Driver No 30 0.149 8 1 0.125 4
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0003006 Not Cancer Driver No 49 0.098 151 19 0.126 2
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0003006 Not Cancer Driver No 33 0.097 8 0 0.0 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:0003006 Not Cancer Driver No 60 0.11 244 26 0.107 0
RFX2_ENST00000359161 RFX2 P48378 DNA-binding protein RFX2 chr19 GO:0003006 Not Cancer Driver No 79 0.109 301 30 0.1 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0003006 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0003006 Not Cancer Driver No 38 0.153 150 25 0.167 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0003006 Not Cancer Driver No 133 0.181 91 15 0.165 0
RSPO3 RSPO3 Q9BXY4 R-spondin-3 chr6 GO:0003006 Census Yes 44 0.162 100 12 0.12 0
RTCB RTCB Q9Y3I0 RNA-splicing ligase RtcB homolog chr22 GO:0003006 Not Cancer Driver No 57 0.113 74 7 0.095 0
SAFB2 SAFB2 Q14151 Scaffold attachment factor B2 chr19 GO:0003006 Not Cancer Driver No 97 0.102 931 88 0.095 0
SALL1 SALL1 Q9NSC2 Sal-like protein 1 chr16 GO:0003006 Not Cancer Driver No 454 0.343 949 334 0.352 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0003006 Not Cancer Driver No 31 0.1 259 30 0.116 0
SEBOX SEBOX Q9HB31 Homeobox protein SEBOX chr17 GO:0003006 Not Cancer Driver No 16 0.084 123 10 0.081 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0003006 Not Cancer Driver No 73 0.124 285 38 0.133 0
SERPINB5 SERPINB5 P36952 Serpin B5 chr18 GO:0003006 Not Cancer Driver No 57 0.152 50 7 0.14 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0003006 Not Cancer Driver No 62 0.156 0 0 0.0 0
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0003006 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SF1_ENST00000377390 SF1 Q15637 Splicing factor 1 chr11 GO:0003006 Not Cancer Driver No 110 0.172 627 106 0.169 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0003006 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGPL1 SGPL1 O95470 Sphingosine-1-phosphate lyase 1 chr10 GO:0003006 Not Cancer Driver No 68 0.12 19 3 0.158 2
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0003006 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIX4 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0003006 Not Cancer Driver No 99 0.127 460 58 0.126 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0003006 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0003006 Not Cancer Driver No 44 0.095 172 11 0.064 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0003006 Not Cancer Driver No 52 0.197 97 11 0.113 0
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0003006 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0003006 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOHLH1_ENST00000298466 SOHLH1 Q5JUK2 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 chr9 GO:0003006 Not Cancer Driver No 48 0.146 252 39 0.155 0
SOHLH2 SOHLH2 Q9NX45 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 chr13 GO:0003006 Compendium Yes 96 0.226 70 14 0.2 0
SOX15_ENST00000538513 SOX15 O60248 Protein SOX-15 chr17 GO:0003006 Not Cancer Driver No 18 0.077 227 18 0.079 0
SOX3 SOX3 P41225 Transcription factor SOX-3 chrX GO:0003006 Not Cancer Driver No 63 0.141 341 61 0.179 0
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0003006 Not Cancer Driver No 43 0.096 403 39 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0003006 Compendium Yes 86 0.169 495 82 0.166 18
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0003006 Not Cancer Driver No 66 0.085 587 37 0.063 0
SPACA1 SPACA1 Q9HBV2 Sperm acrosome membrane-associated protein 1 chr6 GO:0003006 Not Cancer Driver No 65 0.221 79 9 0.114 0
SPATA2_ENST00000289431 SPATA2 Q9UM82 Spermatogenesis-associated protein 2 chr20 GO:0003006 Not Cancer Driver No 70 0.135 235 39 0.166 0
SPEM1 SPEM1 Q8N4L4 Spermatid maturation protein 1 chr17 GO:0003006 Not Cancer Driver No 55 0.178 217 39 0.18 0
SPINK2_ENST00000248701 SPINK2 P20155 Serine protease inhibitor Kazal-type 2 chr4 GO:0003006 Not Cancer Driver No 10 0.119 0 0 0.0 0
SPINT1 SPINT1 O43278 Kunitz-type protease inhibitor 1 chr15 GO:0003006 Not Cancer Driver No 63 0.119 75 12 0.16 0
SPINT2 SPINT2 O43291 Kunitz-type protease inhibitor 2 chr19 GO:0003006 Not Cancer Driver No 46 0.183 25 3 0.12 1
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0003006 Not Cancer Driver No 59 0.149 26 5 0.192 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0003006 Not Cancer Driver No 56 0.178 296 54 0.182 0
SPRR2A SPRR2A P35326 Small proline-rich protein 2A chr1 GO:0003006 Not Cancer Driver No 20 0.278 0 0 0.0 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0003006 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0003006 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0003006 Not Cancer Driver No 48 0.189 0 0 0.0 21
SRY SRY Q05066 Sex-determining region Y protein chrY GO:0003006 Not Cancer Driver No 8 0.039 105 2 0.019 27
ST14 ST14 Q9Y5Y6 Suppressor of tumorigenicity 14 protein chr11 GO:0003006 Not Cancer Driver No 106 0.124 47 5 0.106 1
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0003006 Census, Compendium Yes 93 0.118 144 19 0.132 5
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0003006 Not Cancer Driver No 59 0.239 58 12 0.207 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 GO:0003006 Not Cancer Driver No 71 0.235 112 29 0.259 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0003006 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0003006 Not Cancer Driver No 70 0.144 231 30 0.13 0
STOX2 STOX2 Q9P2F5 Storkhead-box protein 2 chr4 GO:0003006 Not Cancer Driver No 132 0.143 805 115 0.143 0
STRA6_ENST00000323940 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 GO:0003006 Not Cancer Driver No 77 0.115 84 14 0.167 6
STRA8 STRA8 Q7Z7C7 Stimulated by retinoic acid gene 8 protein homolog chr7 GO:0003006 Not Cancer Driver No 45 0.136 105 15 0.143 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0003006 Not Cancer Driver No 97 0.163 111 23 0.207 18
SYCP2_ENST00000371001 SYCP2 Q9BX26 Synaptonemal complex protein 2 chr20 GO:0003006 Not Cancer Driver No 247 0.161 761 121 0.159 0
TAF4 TAF4 O00268 Transcription initiation factor TFIID subunit 4 chr20 GO:0003006 Not Cancer Driver No 112 0.103 975 96 0.098 0
TAF4B_ENST00000269142 TAF4B Q92750 Transcription initiation factor TFIID subunit 4B chr18 GO:0003006 Not Cancer Driver No 86 0.1 482 46 0.095 0
TBC1D20 TBC1D20 Q96BZ9 TBC1 domain family member 20 chr20 GO:0003006 Not Cancer Driver No 52 0.129 99 10 0.101 0
TBC1D21 TBC1D21 Q8IYX1 TBC1 domain family member 21 chr15 GO:0003006 Not Cancer Driver No 62 0.185 7 0 0.0 0
TBPL1 TBPL1 P62380 TATA box-binding protein-like 1 chr6 GO:0003006 Not Cancer Driver No 27 0.145 6 0 0.0 0
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0003006 Census, Compendium Yes 123 0.166 352 57 0.162 2
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0003006 Not Cancer Driver No 55 0.307 120 40 0.333 0
TCF23 TCF23 Q7RTU1 Transcription factor 23 chr2 GO:0003006 Not Cancer Driver No 45 0.21 156 33 0.212 0
TEX19 TEX19 Q8NA77 Testis-expressed protein 19 chr17 GO:0003006 Not Cancer Driver No 26 0.159 93 14 0.151 0
TFEB_ENST00000403298 TFEB P19484 Transcription factor EB chr6 GO:0003006 Census Yes 58 0.122 429 47 0.11 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0003006 Not Cancer Driver No 63 0.152 47 8 0.17 3
TIFAB TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 GO:0003006 Not Cancer Driver No 32 0.199 26 7 0.269 0
TIPARP TIPARP Q7Z3E1 Protein mono-ADP-ribosyltransferase TIPARP chr3 GO:0003006 Not Cancer Driver No 65 0.099 200 20 0.1 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0003006 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMF1 TMF1 P82094 TATA element modulatory factor chr3 GO:0003006 Not Cancer Driver No 109 0.1 946 99 0.105 0
TNC TNC P24821 Tenascin chr9 GO:0003006 Census, Compendium Yes 354 0.161 568 123 0.217 2
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0003006 Census, Compendium Yes 229 0.337 398 143 0.359 28
TPPP3_ENST00000393957 TPPP3 Q9BW30 Tubulin polymerization-promoting protein family member 3 chr16 GO:0003006 Not Cancer Driver No 21 0.119 63 10 0.159 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0003006 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 GO:0003006 Not Cancer Driver No 62 0.144 30 6 0.2 1
TSPY1 TSPY1 Q01534 Testis-specific Y-encoded protein 1 chrY GO:0003006 Not Cancer Driver No 4 0.013 118 1 0.008 0
TSPY2_ENST00000320701 TSPY2 A6NKD2 Testis-specific Y-encoded protein 2 chrY GO:0003006 Not Cancer Driver No 12 0.039 116 4 0.034 0
TSPY8_ENST00000287721 TSPY8 P0CW00 Testis-specific Y-encoded protein 8 chrY GO:0003006 Not Cancer Driver No 6 0.019 106 2 0.019 0
TTPA TTPA P49638 Alpha-tocopherol transfer protein chr8 GO:0003006 Not Cancer Driver No 53 0.191 20 1 0.05 7
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 GO:0003006 Not Cancer Driver No 103 0.232 53 18 0.34 13
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0003006 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0003006 Not Cancer Driver No 159 0.106 659 74 0.112 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0003006 Not Cancer Driver No 119 0.134 197 17 0.086 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0003006 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0003006 Not Cancer Driver No 141 0.161 136 22 0.162 0
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 GO:0003006 Not Cancer Driver No 39 0.107 215 18 0.084 0
VASH2 VASH2 Q86V25 Tubulinyl-Tyr carboxypeptidase 2 chr1 GO:0003006 Not Cancer Driver No 32 0.09 106 9 0.085 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0003006 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0003006 Not Cancer Driver No 27 0.116 41 7 0.171 0
VGF VGF O15240 Neurosecretory protein VGF chr7 GO:0003006 Not Cancer Driver No 48 0.078 593 47 0.079 0
WASHC5 WASHC5 Q12768 WASH complex subunit 5 chr8 GO:0003006 Not Cancer Driver No 152 0.131 23 6 0.261 6
WDR19 WDR19 Q8NEZ3 WD repeat-containing protein 19 chr4 GO:0003006 Not Cancer Driver No 117 0.087 19 0 0.0 11
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0003006 Not Cancer Driver No 61 0.09 125 19 0.152 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 GO:0003006 Not Cancer Driver No 30 0.088 41 2 0.049 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0003006 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0003006 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0003006 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0003006 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0003006 Not Cancer Driver No 55 0.158 11 1 0.091 0
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0003006 Not Cancer Driver No 47 0.132 11 4 0.364 0
YBX2 YBX2 Q9Y2T7 Y-box-binding protein 2 chr17 GO:0003006 Not Cancer Driver No 48 0.132 342 46 0.135 0
YTHDC2 YTHDC2 Q9H6S0 3'-5' RNA helicase YTHDC2 chr5 GO:0003006 Not Cancer Driver No 163 0.114 439 48 0.109 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0003006 Not Cancer Driver No 67 0.116 376 44 0.117 0
ZFP42_ENST00000509524 ZFP42 Q96MM3 Zinc finger protein 42 homolog chr4 GO:0003006 Not Cancer Driver No 135 0.435 76 27 0.355 0
ZFPM2 ZFPM2 Q8WW38 Zinc finger protein ZFPM2 chr8 GO:0003006 Not Cancer Driver No 374 0.325 659 233 0.354 8
ZFY_ENST00000155093 ZFY P08048 Zinc finger Y-chromosomal protein chrY GO:0003006 Not Cancer Driver No 29 0.036 357 8 0.022 0
ZGLP1 ZGLP1 P0C6A0 GATA-type zinc finger protein 1 chr19 GO:0003006 Not Cancer Driver No 24 0.089 191 17 0.089 0
ZNF568_ENST00000333987 ZNF568 Q3ZCX4 Zinc finger protein 568 chr19 GO:0003006 Not Cancer Driver No 112 0.174 111 24 0.216 0
ZNF830 ZNF830 Q96NB3 Zinc finger protein 830 chr17 GO:0003006 Not Cancer Driver No 39 0.105 312 37 0.119 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0003006 Not Cancer Driver No 55 0.13 56 11 0.196 1
ZPBP ZPBP Q9BS86 Zona pellucida-binding protein 1 chr7 GO:0003006 Not Cancer Driver No 100 0.285 5 0 0.0 0
ZPBP2 ZPBP2 Q6X784 Zona pellucida-binding protein 2 chr17 GO:0003006 Not Cancer Driver No 47 0.139 7 1 0.143 0