Total number of protein in "GO:0002833" GO term: 111
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACOD1 | ACOD1 | A6NK06 | Cis-aconitate decarboxylase | chr13 | GO:0002833 | Not Cancer Driver | No | 5 | 0.01 | 36 | 0 | 0.0 | 0 |
ANKRD17 | ANKRD17 | O75179 | Ankyrin repeat domain-containing protein 17 | chr4 | GO:0002833 | Not Cancer Driver | No | 312 | 0.12 | 1790 | 221 | 0.123 | 9 |
AP1G1_ENST00000569748 | AP1G1 | O43747 | AP-1 complex subunit gamma-1 | chr16 | GO:0002833 | Not Cancer Driver | No | 111 | 0.135 | 144 | 22 | 0.153 | 0 |
ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0002833 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
BMP6 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0002833 | Not Cancer Driver | No | 95 | 0.185 | 226 | 51 | 0.226 | 0 |
CADM1_ENST00000452722 | CADM1 | Q9BY67 | Cell adhesion molecule 1 | chr11 | GO:0002833 | Not Cancer Driver | No | 106 | 0.24 | 103 | 28 | 0.272 | 0 |
CD160_ENST00000369288 | CD160 | O95971 | CD160 antigen | chr1 | GO:0002833 | Not Cancer Driver | No | 20 | 0.11 | 2 | 0 | 0.0 | 0 |
CD180 | CD180 | Q99467 | CD180 antigen | chr5 | GO:0002833 | Not Cancer Driver | No | 105 | 0.159 | 0 | 0 | 0.0 | 0 |
CD226_ENST00000582621 | CD226 | Q15762 | CD226 antigen | chr18 | GO:0002833 | Not Cancer Driver | No | 79 | 0.235 | 47 | 11 | 0.234 | 0 |
CD274 | CD274 | Q9NZQ7 | Programmed cell death 1 ligand 1 | chr9 | GO:0002833 | Census | Yes | 29 | 0.1 | 54 | 9 | 0.167 | 0 |
CLEC6A | CLEC6A | Q6EIG7 | C-type lectin domain family 6 member A | chr12 | GO:0002833 | Not Cancer Driver | No | 41 | 0.196 | 7 | 0 | 0.0 | 0 |
CLEC7A | CLEC7A | Q9BXN2 | C-type lectin domain family 7 member A | chr12 | GO:0002833 | Not Cancer Driver | No | 43 | 0.174 | 46 | 2 | 0.043 | 0 |
CLNK | CLNK | Q7Z7G1 | Cytokine-dependent hematopoietic cell linker | chr4 | GO:0002833 | Not Cancer Driver | No | 85 | 0.199 | 320 | 73 | 0.228 | 0 |
CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0002833 | Census, Compendium | Yes | 412 | 0.169 | 1796 | 247 | 0.138 | 33 |
CRTAM | CRTAM | O95727 | Cytotoxic and regulatory T-cell molecule | chr11 | GO:0002833 | Not Cancer Driver | No | 64 | 0.163 | 135 | 14 | 0.104 | 0 |
CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | GO:0002833 | Not Cancer Driver | No | 26 | 0.133 | 66 | 2 | 0.03 | 12 |
DDX60 | DDX60 | Q8IY21 | Probable ATP-dependent RNA helicase DDX60 | chr4 | GO:0002833 | Not Cancer Driver | No | 224 | 0.131 | 131 | 12 | 0.092 | 0 |
DHX58 | DHX58 | Q96C10 | ATP-dependent RNA helicase DHX58 | chr17 | GO:0002833 | Not Cancer Driver | No | 62 | 0.091 | 84 | 8 | 0.095 | 0 |
EMILIN1 | EMILIN1 | Q9Y6C2 | EMILIN-1 | chr2 | GO:0002833 | Not Cancer Driver | No | 125 | 0.123 | 669 | 69 | 0.103 | 0 |
EMILIN2 | EMILIN2 | Q9BXX0 | EMILIN-2 | chr18 | GO:0002833 | Not Cancer Driver | No | 158 | 0.15 | 617 | 94 | 0.152 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0002833 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0002833 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0002833 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
FBXO38_ENST00000340253 | FBXO38 | Q6PIJ6 | F-box only protein 38 | chr5 | GO:0002833 | Not Cancer Driver | No | 133 | 0.112 | 440 | 48 | 0.109 | 1 |
FCN1 | FCN1 | O00602 | Ficolin-1 | chr9 | GO:0002833 | Not Cancer Driver | No | 107 | 0.328 | 88 | 15 | 0.17 | 0 |
FFAR2 | FFAR2 | O15552 | Free fatty acid receptor 2 | chr19 | GO:0002833 | Not Cancer Driver | No | 49 | 0.148 | 32 | 7 | 0.219 | 0 |
FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0002833 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
GRN | GRN | P28799 | Progranulin | chr17 | GO:0002833 | Not Cancer Driver | No | 76 | 0.128 | 29 | 6 | 0.207 | 1 |
HAVCR2 | HAVCR2 | Q8TDQ0 | Hepatitis A virus cellular receptor 2 | chr5 | GO:0002833 | Not Cancer Driver | No | 69 | 0.229 | 17 | 2 | 0.118 | 3 |
HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0002833 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
HLA-DRB1 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | GO:0002833 | Not Cancer Driver | No | 48 | 0.18 | 12 | 1 | 0.083 | 0 |
HLA-E | HLA-E | P13747 | HLA class I histocompatibility antigen, alpha chain E | chr6 | GO:0002833 | Not Cancer Driver | No | 63 | 0.176 | 138 | 39 | 0.283 | 0 |
HLA-F_ENST00000376861 | HLA-F | P30511 | HLA class I histocompatibility antigen, alpha chain F | chr6 | GO:0002833 | Not Cancer Driver | No | 43 | 0.124 | 115 | 22 | 0.191 | 0 |
HLA-G_ENST00000360323 | HLA-G | P17693 | HLA class I histocompatibility antigen, alpha chain G | chr6 | GO:0002833 | Not Cancer Driver | No | 94 | 0.278 | 85 | 22 | 0.259 | 0 |
HPX | HPX | P02790 | Hemopexin | chr11 | GO:0002833 | Not Cancer Driver | No | 60 | 0.13 | 53 | 8 | 0.151 | 0 |
HRG | HRG | P04196 | Histidine-rich glycoprotein | chr3 | GO:0002833 | Not Cancer Driver | No | 121 | 0.23 | 277 | 75 | 0.271 | 2 |
HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0002833 | Not Cancer Driver | No | 61 | 0.106 | 82 | 6 | 0.073 | 2 |
IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | GO:0002833 | Census, Compendium | Yes | 106 | 0.14 | 211 | 31 | 0.147 | 1 |
IKBKE | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | GO:0002833 | Not Cancer Driver | No | 108 | 0.151 | 76 | 13 | 0.171 | 0 |
IL12B | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:0002833 | Not Cancer Driver | No | 48 | 0.146 | 42 | 2 | 0.048 | 0 |
IL17A | IL17A | Q16552 | Interleukin-17A | chr6 | GO:0002833 | Not Cancer Driver | No | 52 | 0.335 | 56 | 21 | 0.375 | 0 |
IL17F | IL17F | Q96PD4 | Interleukin-17F | chr6 | GO:0002833 | Not Cancer Driver | No | 42 | 0.258 | 34 | 11 | 0.324 | 1 |
IRF3_ENST00000597198 | IRF3 | Q14653 | Interferon regulatory factor 3 | chr19 | GO:0002833 | Not Cancer Driver | No | 36 | 0.084 | 204 | 21 | 0.103 | 1 |
IRF7_ENST00000397574 | IRF7 | Q92985 | Interferon regulatory factor 7 | chr11 | GO:0002833 | Not Cancer Driver | No | 43 | 0.085 | 253 | 19 | 0.075 | 1 |
IRGM | IRGM | A1A4Y4 | Immunity-related GTPase family M protein | chr5 | GO:0002833 | Not Cancer Driver | No | 9 | 0.05 | 45 | 1 | 0.022 | 0 |
KLK3 | KLK3 | P07288 | Prostate-specific antigen | chr19 | GO:0002833 | Not Cancer Driver | No | 68 | 0.261 | 6 | 1 | 0.167 | 0 |
KLK5_ENST00000593428 | KLK5 | Q9Y337 | Kallikrein-5 | chr19 | GO:0002833 | Not Cancer Driver | No | 69 | 0.235 | 75 | 16 | 0.213 | 0 |
KLK7 | KLK7 | P49862 | Kallikrein-7 | chr19 | GO:0002833 | Not Cancer Driver | No | 43 | 0.17 | 38 | 8 | 0.211 | 0 |
KLRC2 | KLRC2 | P26717 | NKG2-C type II integral membrane protein | chr12 | GO:0002833 | Not Cancer Driver | No | 55 | 0.238 | 45 | 17 | 0.378 | 0 |
KLRC3_ENST00000396439 | KLRC3 | Q07444 | NKG2-E type II integral membrane protein | chr12 | GO:0002833 | Not Cancer Driver | No | 37 | 0.154 | 43 | 4 | 0.093 | 0 |
KLRC4 | KLRC4 | O43908 | NKG2-F type II integral membrane protein | chr12 | GO:0002833 | Not Cancer Driver | No | 36 | 0.228 | 45 | 7 | 0.156 | 0 |
KLRD1 | KLRD1 | Q13241 | Natural killer cells antigen CD94 | chr12 | GO:0002833 | Not Cancer Driver | No | 37 | 0.207 | 0 | 0 | 0.0 | 0 |
KLRK1 | KLRK1 | P26718 | NKG2-D type II integral membrane protein | chr12 | GO:0002833 | Not Cancer Driver | No | 38 | 0.176 | 0 | 0 | 0.0 | 0 |
LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | GO:0002833 | Not Cancer Driver | No | 47 | 0.113 | 93 | 10 | 0.108 | 0 |
LBP | LBP | P18428 | Lipopolysaccharide-binding protein | chr20 | GO:0002833 | Not Cancer Driver | No | 84 | 0.175 | 6 | 0 | 0.0 | 0 |
LILRA2 | LILRA2 | Q8N149 | Leukocyte immunoglobulin-like receptor subfamily A member 2 | chr19 | GO:0002833 | Not Cancer Driver | No | 163 | 0.337 | 137 | 44 | 0.321 | 0 |
LSM14A_ENST00000433627 | LSM14A | Q8ND56 | Protein LSM14 homolog A | chr19 | GO:0002833 | Census | Yes | 67 | 0.145 | 408 | 63 | 0.154 | 0 |
LY86 | LY86 | O95711 | Lymphocyte antigen 86 | chr6 | GO:0002833 | Not Cancer Driver | No | 29 | 0.179 | 0 | 0 | 0.0 | 0 |
LY96 | LY96 | Q9Y6Y9 | Lymphocyte antigen 96 | chr8 | GO:0002833 | Not Cancer Driver | No | 37 | 0.231 | 0 | 0 | 0.0 | 0 |
LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0002833 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0002833 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
MAVS | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | GO:0002833 | Not Cancer Driver | No | 70 | 0.13 | 411 | 58 | 0.141 | 0 |
MBL2 | MBL2 | P11226 | Mannose-binding protein C | chr10 | GO:0002833 | Not Cancer Driver | No | 63 | 0.254 | 122 | 32 | 0.262 | 0 |
MED1 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0002833 | Not Cancer Driver | No | 162 | 0.102 | 1104 | 117 | 0.106 | 0 |
MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:0002833 | Not Cancer Driver | No | 4 | 0.035 | 0 | 0 | 0.0 | 0 |
MMP12 | MMP12 | P39900 | Macrophage metalloelastase | chr11 | GO:0002833 | Not Cancer Driver | No | 100 | 0.213 | 29 | 5 | 0.172 | 0 |
MR1 | MR1 | Q95460 | Major histocompatibility complex class I-related gene protein | chr1 | GO:0002833 | Not Cancer Driver | No | 60 | 0.176 | 33 | 7 | 0.212 | 0 |
NECTIN2 | NECTIN2 | Q92692 | Nectin-2 | chr19 | GO:0002833 | Not Cancer Driver | No | 63 | 0.117 | 296 | 29 | 0.098 | 0 |
NLRC5_ENST00000436936 | NLRC5 | Q86WI3 | Protein NLRC5 | chr16 | GO:0002833 | Not Cancer Driver | No | 262 | 0.14 | 114 | 19 | 0.167 | 0 |
NLRP10 | NLRP10 | Q86W26 | NACHT, LRR and PYD domains-containing protein 10 | chr11 | GO:0002833 | Not Cancer Driver | No | 201 | 0.307 | 96 | 34 | 0.354 | 0 |
NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0002833 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
OASL | OASL | Q15646 | 2'-5'-oligoadenylate synthase-like protein | chr12 | GO:0002833 | Not Cancer Driver | No | 76 | 0.148 | 8 | 4 | 0.5 | 0 |
PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0002833 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0002833 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0002833 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
PARP9 | PARP9 | Q8IXQ6 | Protein mono-ADP-ribosyltransferase PARP9 | chr3 | GO:0002833 | Not Cancer Driver | No | 110 | 0.129 | 45 | 3 | 0.067 | 0 |
PGC | PGC | P20142 | Gastricsin | chr6 | GO:0002833 | Not Cancer Driver | No | 60 | 0.155 | 20 | 1 | 0.05 | 0 |
PLA2G5 | PLA2G5 | P39877 | Phospholipase A2 group V | chr1 | GO:0002833 | Not Cancer Driver | No | 24 | 0.174 | 0 | 0 | 0.0 | 2 |
PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0002833 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0002833 | Not Cancer Driver | No | 94 | 0.14 | 154 | 22 | 0.143 | 0 |
PUM1_ENST00000257075 | PUM1 | Q14671 | Pumilio homolog 1 | chr1 | GO:0002833 | Not Cancer Driver | No | 150 | 0.126 | 640 | 77 | 0.12 | 3 |
PUM2_ENST00000403432 | PUM2 | Q8TB72 | Pumilio homolog 2 | chr2 | GO:0002833 | Not Cancer Driver | No | 132 | 0.124 | 575 | 83 | 0.144 | 0 |
PVR | PVR | P15151 | Poliovirus receptor | chr19 | GO:0002833 | Not Cancer Driver | No | 39 | 0.094 | 120 | 19 | 0.158 | 0 |
RAET1G | RAET1G | Q6H3X3 | UL-16 binding protein 5 | chr6 | GO:0002833 | Not Cancer Driver | No | 41 | 0.123 | 62 | 10 | 0.161 | 0 |
RNF185 | RNF185 | Q96GF1 | E3 ubiquitin-protein ligase RNF185 | chr22 | GO:0002833 | Not Cancer Driver | No | 25 | 0.13 | 82 | 15 | 0.183 | 0 |
RPS19_ENST00000600467 | RPS19 | P39019 | 40S ribosomal protein S19 | chr19 | GO:0002833 | Not Cancer Driver | No | 15 | 0.103 | 61 | 3 | 0.049 | 23 |
SASH1 | SASH1 | O94885 | SAM and SH3 domain-containing protein 1 | chr6 | GO:0002833 | Not Cancer Driver | No | 174 | 0.14 | 1071 | 153 | 0.143 | 7 |
SCIMP | SCIMP | Q6UWF3 | SLP adapter and CSK-interacting membrane protein | chr17 | GO:0002833 | Not Cancer Driver | No | 10 | 0.069 | 73 | 9 | 0.123 | 0 |
SH2D1B | SH2D1B | O14796 | SH2 domain-containing protein 1B | chr1 | GO:0002833 | Not Cancer Driver | No | 34 | 0.258 | 0 | 0 | 0.0 | 0 |
SLC22A13 | SLC22A13 | Q9Y226 | Solute carrier family 22 member 13 | chr3 | GO:0002833 | Not Cancer Driver | No | 55 | 0.1 | 32 | 3 | 0.094 | 0 |
SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0002833 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0002833 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0002833 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0002833 | Not Cancer Driver | No | 101 | 0.139 | 42 | 5 | 0.119 | 12 |
TMEM173 | STING1 | Q86WV6 | Stimulator of interferon genes protein | chr5 | GO:0002833 | Not Cancer Driver | No | 46 | 0.121 | 66 | 13 | 0.197 | 3 |
TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0002833 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
TRIM15 | TRIM15 | Q9C019 | Tripartite motif-containing protein 15 | chr6 | GO:0002833 | Not Cancer Driver | No | 69 | 0.148 | 79 | 11 | 0.139 | 0 |
TRIM41 | TRIM41 | Q8WV44 | E3 ubiquitin-protein ligase TRIM41 | chr5 | GO:0002833 | Not Cancer Driver | No | 69 | 0.11 | 385 | 38 | 0.099 | 0 |
TRIM56 | TRIM56 | Q9BRZ2 | E3 ubiquitin-protein ligase TRIM56 | chr7 | GO:0002833 | Not Cancer Driver | No | 110 | 0.146 | 217 | 36 | 0.166 | 0 |
TRIM62 | TRIM62 | Q9BVG3 | E3 ubiquitin-protein ligase TRIM62 | chr1 | GO:0002833 | Not Cancer Driver | No | 58 | 0.122 | 80 | 14 | 0.175 | 0 |
TRIM6_ENST00000278302 | TRIM6 | Q9C030 | Tripartite motif-containing protein 6 | chr11 | GO:0002833 | Not Cancer Driver | No | 86 | 0.176 | 47 | 15 | 0.319 | 0 |
TXK | TXK | P42681 | Tyrosine-protein kinase TXK | chr4 | GO:0002833 | Not Cancer Driver | No | 87 | 0.165 | 61 | 9 | 0.148 | 0 |
TYROBP | TYROBP | O43914 | TYRO protein tyrosine kinase-binding protein | chr19 | GO:0002833 | Not Cancer Driver | No | 24 | 0.212 | 28 | 8 | 0.286 | 0 |
UBE2K | UBE2K | P61086 | Ubiquitin-conjugating enzyme E2 K | chr4 | GO:0002833 | Not Cancer Driver | No | 24 | 0.12 | 33 | 3 | 0.091 | 0 |
USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | GO:0002833 | Not Cancer Driver | No | 136 | 0.139 | 259 | 39 | 0.151 | 0 |
USP17L2 | USP17L2 | Q6R6M4 | Ubiquitin carboxyl-terminal hydrolase 17 | chr8 | GO:0002833 | Not Cancer Driver | No | 105 | 0.198 | 201 | 54 | 0.269 | 0 |
USP27X | USP27X | A6NNY8 | Ubiquitin carboxyl-terminal hydrolase 27 | chrX | GO:0002833 | Not Cancer Driver | No | 31 | 0.071 | 69 | 3 | 0.043 | 1 |
USP29_ENST00000598197 | USP29 | Q9HBJ7 | Ubiquitin carboxyl-terminal hydrolase 29 | chr19 | GO:0002833 | Not Cancer Driver | No | 291 | 0.316 | 432 | 132 | 0.306 | 0 |
WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0002833 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
ZBP1 | ZBP1 | Q9H171 | Z-DNA-binding protein 1 | chr20 | GO:0002833 | Not Cancer Driver | No | 97 | 0.226 | 385 | 80 | 0.208 | 0 |
ZCCHC3 | ZCCHC3 | Q9NUD5 | Zinc finger CCHC domain-containing protein 3 | chr20 | GO:0002833 | Not Cancer Driver | No | 28 | 0.069 | 160 | 1 | 0.006 | 0 |