Total number of protein in "GO:0002768" GO term: 86
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0002768 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0002768 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BLK | BLK | P51451 | Tyrosine-protein kinase Blk | chr8 | GO:0002768 | Not Cancer Driver | No | 94 | 0.186 | 75 | 21 | 0.28 | 0 |
| BTK_ENST00000308731 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | GO:0002768 | Census, Compendium | Yes | 147 | 0.223 | 114 | 27 | 0.237 | 110 |
| BTLA | BTLA | Q7Z6A9 | B- and T-lymphocyte attenuator | chr3 | GO:0002768 | Not Cancer Driver | No | 31 | 0.107 | 57 | 5 | 0.088 | 0 |
| C3AR1 | C3AR1 | Q16581 | C3a anaphylatoxin chemotactic receptor | chr12 | GO:0002768 | Not Cancer Driver | No | 88 | 0.183 | 72 | 16 | 0.222 | 0 |
| C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | GO:0002768 | Not Cancer Driver | No | 71 | 0.203 | 0 | 0 | 0.0 | 0 |
| C5AR2_ENST00000600626 | C5AR2 | Q9P296 | C5a anaphylatoxin chemotactic receptor 2 | chr19 | GO:0002768 | Not Cancer Driver | No | 60 | 0.178 | 11 | 3 | 0.273 | 0 |
| CD200R1_ENST00000471858 | CD200R1 | Q8TD46 | Cell surface glycoprotein CD200 receptor 1 | chr3 | GO:0002768 | Not Cancer Driver | No | 87 | 0.268 | 56 | 12 | 0.214 | 0 |
| CD40 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0002768 | Not Cancer Driver | No | 39 | 0.141 | 56 | 6 | 0.107 | 2 |
| CLEC12B | CLEC12B | Q2HXU8 | C-type lectin domain family 12 member B | chr12 | GO:0002768 | Not Cancer Driver | No | 34 | 0.123 | 57 | 8 | 0.14 | 0 |
| CLEC4D | CLEC4D | Q8WXI8 | C-type lectin domain family 4 member D | chr12 | GO:0002768 | Not Cancer Driver | No | 59 | 0.274 | 17 | 3 | 0.176 | 0 |
| CLEC4E | CLEC4E | Q9ULY5 | C-type lectin domain family 4 member E | chr12 | GO:0002768 | Not Cancer Driver | No | 56 | 0.256 | 5 | 2 | 0.4 | 0 |
| CLEC6A | CLEC6A | Q6EIG7 | C-type lectin domain family 6 member A | chr12 | GO:0002768 | Not Cancer Driver | No | 41 | 0.196 | 7 | 0 | 0.0 | 0 |
| CLEC7A | CLEC7A | Q9BXN2 | C-type lectin domain family 7 member A | chr12 | GO:0002768 | Not Cancer Driver | No | 43 | 0.174 | 46 | 2 | 0.043 | 0 |
| CMKLR1 | CMKLR1 | Q99788 | Chemerin-like receptor 1 | chr12 | GO:0002768 | Not Cancer Driver | No | 107 | 0.287 | 24 | 13 | 0.542 | 0 |
| CR1_ENST00000367053 | CR1 | P17927 | Complement receptor type 1 | chr1 | GO:0002768 | Compendium | Yes | 383 | 0.188 | 151 | 42 | 0.278 | 0 |
| CR2_ENST00000367058 | CR2 | P20023 | Complement receptor type 2 | chr1 | GO:0002768 | Not Cancer Driver | No | 273 | 0.264 | 85 | 28 | 0.329 | 0 |
| CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0002768 | Census, Compendium | Yes | 412 | 0.169 | 1796 | 247 | 0.138 | 33 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0002768 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
| FCER1G | FCER1G | P30273 | High affinity immunoglobulin epsilon receptor subunit gamma | chr1 | GO:0002768 | Not Cancer Driver | No | 10 | 0.116 | 13 | 2 | 0.154 | 0 |
| FCGR1B | FCGR1BP | Q92637 | Putative high affinity immunoglobulin gamma Fc receptor IB | chr1 | GO:0002768 | Not Cancer Driver | No | 31 | 0.111 | 37 | 6 | 0.162 | 0 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0002768 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FCGR3A_ENST00000443193 | FCGR3A | P08637 | Low affinity immunoglobulin gamma Fc region receptor III-A | chr1 | GO:0002768 | Not Cancer Driver | No | 69 | 0.272 | 0 | 0 | 0.0 | 1 |
| FCN1 | FCN1 | O00602 | Ficolin-1 | chr9 | GO:0002768 | Not Cancer Driver | No | 107 | 0.328 | 88 | 15 | 0.17 | 0 |
| FER | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | GO:0002768 | Not Cancer Driver | No | 114 | 0.139 | 145 | 21 | 0.145 | 0 |
| FFAR2 | FFAR2 | O15552 | Free fatty acid receptor 2 | chr19 | GO:0002768 | Not Cancer Driver | No | 49 | 0.148 | 32 | 7 | 0.219 | 0 |
| FGR_ENST00000374004 | FGR | P09769 | Tyrosine-protein kinase Fgr | chr1 | GO:0002768 | Not Cancer Driver | No | 85 | 0.161 | 52 | 8 | 0.154 | 0 |
| FPR1_ENST00000304748 | FPR1 | P21462 | fMet-Leu-Phe receptor | chr19 | GO:0002768 | Not Cancer Driver | No | 99 | 0.283 | 18 | 3 | 0.167 | 0 |
| FPR2 | FPR2 | P25090 | N-formyl peptide receptor 2 | chr19 | GO:0002768 | Not Cancer Driver | No | 96 | 0.274 | 26 | 5 | 0.192 | 0 |
| FPR3 | FPR3 | P25089 | N-formyl peptide receptor 3 | chr19 | GO:0002768 | Not Cancer Driver | No | 82 | 0.232 | 28 | 2 | 0.071 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0002768 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| GPLD1 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0002768 | Not Cancer Driver | No | 153 | 0.182 | 36 | 9 | 0.25 | 0 |
| GPR32 | GPR32 | O75388 | Probable G-protein coupled receptor 32 | chr19 | GO:0002768 | Not Cancer Driver | No | 85 | 0.239 | 18 | 6 | 0.333 | 0 |
| HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0002768 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
| HLA-G_ENST00000360323 | HLA-G | P17693 | HLA class I histocompatibility antigen, alpha chain G | chr6 | GO:0002768 | Not Cancer Driver | No | 94 | 0.278 | 85 | 22 | 0.259 | 0 |
| IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | GO:0002768 | Census, Compendium | Yes | 106 | 0.14 | 211 | 31 | 0.147 | 1 |
| KIR2DL1 | KIR2DL1 | P43626 | Killer cell immunoglobulin-like receptor 2DL1 | chr19 | GO:0002768 | Not Cancer Driver | No | 112 | 0.322 | 135 | 44 | 0.326 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0002768 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| KLRC1 | KLRC1 | P26715 | NKG2-A/NKG2-B type II integral membrane protein | chr12 | GO:0002768 | Not Cancer Driver | No | 49 | 0.21 | 49 | 10 | 0.204 | 0 |
| KLRC2 | KLRC2 | P26717 | NKG2-C type II integral membrane protein | chr12 | GO:0002768 | Not Cancer Driver | No | 55 | 0.238 | 45 | 17 | 0.378 | 0 |
| KLRC3_ENST00000396439 | KLRC3 | Q07444 | NKG2-E type II integral membrane protein | chr12 | GO:0002768 | Not Cancer Driver | No | 37 | 0.154 | 43 | 4 | 0.093 | 0 |
| KLRC4 | KLRC4 | O43908 | NKG2-F type II integral membrane protein | chr12 | GO:0002768 | Not Cancer Driver | No | 36 | 0.228 | 45 | 7 | 0.156 | 0 |
| KLRD1 | KLRD1 | Q13241 | Natural killer cells antigen CD94 | chr12 | GO:0002768 | Not Cancer Driver | No | 37 | 0.207 | 0 | 0 | 0.0 | 0 |
| KLRK1 | KLRK1 | P26718 | NKG2-D type II integral membrane protein | chr12 | GO:0002768 | Not Cancer Driver | No | 38 | 0.176 | 0 | 0 | 0.0 | 0 |
| LILRA2 | LILRA2 | Q8N149 | Leukocyte immunoglobulin-like receptor subfamily A member 2 | chr19 | GO:0002768 | Not Cancer Driver | No | 163 | 0.337 | 137 | 44 | 0.321 | 0 |
| LILRA4 | LILRA4 | P59901 | Leukocyte immunoglobulin-like receptor subfamily A member 4 | chr19 | GO:0002768 | Not Cancer Driver | No | 124 | 0.248 | 109 | 26 | 0.239 | 0 |
| LILRB1_ENST00000396331 | LILRB1 | Q8NHL6 | Leukocyte immunoglobulin-like receptor subfamily B member 1 | chr19 | GO:0002768 | Not Cancer Driver | No | 203 | 0.312 | 291 | 97 | 0.333 | 0 |
| LILRB2_ENST00000314446 | LILRB2 | Q8N423 | Leukocyte immunoglobulin-like receptor subfamily B member 2 | chr19 | GO:0002768 | Not Cancer Driver | No | 148 | 0.248 | 235 | 50 | 0.213 | 0 |
| LILRB4 | LILRB4 | Q8NHJ6 | Leukocyte immunoglobulin-like receptor subfamily B member 4 | chr19 | GO:0002768 | Not Cancer Driver | No | 162 | 0.362 | 277 | 115 | 0.415 | 0 |
| LIMK1 | LIMK1 | P53667 | LIM domain kinase 1 | chr7 | GO:0002768 | Not Cancer Driver | No | 110 | 0.17 | 170 | 30 | 0.176 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0002768 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| MAP2K4_ENST00000353533 | MAP2K4 | P45985 | Dual specificity mitogen-activated protein kinase kinase 4 | chr17 | GO:0002768 | Census, Compendium | Yes | 89 | 0.223 | 137 | 28 | 0.204 | 0 |
| MAP2K7_ENST00000397979 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0002768 | Compendium | Yes | 89 | 0.212 | 144 | 20 | 0.139 | 0 |
| MAP3K1 | MAP3K1 | Q13233 | Mitogen-activated protein kinase kinase kinase 1 | chr5 | GO:0002768 | Census, Compendium | Yes | 184 | 0.122 | 820 | 62 | 0.076 | 3 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0002768 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
| MAPK10_ENST00000515650 | MAPK10 | P53779 | Mitogen-activated protein kinase 10 | chr4 | GO:0002768 | Not Cancer Driver | No | 88 | 0.19 | 107 | 16 | 0.15 | 0 |
| MAPK8_ENST00000374189 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0002768 | Not Cancer Driver | No | 64 | 0.15 | 94 | 9 | 0.096 | 0 |
| MAPK9 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | GO:0002768 | Not Cancer Driver | No | 59 | 0.139 | 90 | 8 | 0.089 | 0 |
| MBL2 | MBL2 | P11226 | Mannose-binding protein C | chr10 | GO:0002768 | Not Cancer Driver | No | 63 | 0.254 | 122 | 32 | 0.262 | 0 |
| MS4A2 | MS4A2 | Q01362 | High affinity immunoglobulin epsilon receptor subunit beta | chr11 | GO:0002768 | Not Cancer Driver | No | 64 | 0.262 | 19 | 8 | 0.421 | 0 |
| MYO1G | MYO1G | B0I1T2 | Unconventional myosin-Ig | chr7 | GO:0002768 | Not Cancer Driver | No | 125 | 0.123 | 117 | 12 | 0.103 | 0 |
| NR4A3_ENST00000395097 | NR4A3 | Q92570 | Nuclear receptor subfamily 4 group A member 3 | chr9 | GO:0002768 | Census | Yes | 83 | 0.133 | 298 | 37 | 0.124 | 0 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0002768 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
| PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0002768 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
| PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0002768 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
| PIGR | PIGR | P01833 | Polymeric immunoglobulin receptor | chr1 | GO:0002768 | Not Cancer Driver | No | 126 | 0.165 | 177 | 37 | 0.209 | 0 |
| PLA2G6 | PLA2G6 | O60733 | 85/88 kDa calcium-independent phospholipase A2 | chr22 | GO:0002768 | Not Cancer Driver | No | 108 | 0.134 | 148 | 23 | 0.155 | 11 |
| PLCG1_ENST00000373271 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0002768 | Census, Compendium | Yes | 158 | 0.122 | 186 | 21 | 0.113 | 0 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0002768 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PLD2 | PLD2 | O14939 | Phospholipase D2 | chr17 | GO:0002768 | Not Cancer Driver | No | 107 | 0.115 | 97 | 8 | 0.082 | 0 |
| PLPP4 | PLPP4 | Q5VZY2 | Phospholipid phosphatase 4 | chr10 | GO:0002768 | Not Cancer Driver | No | 59 | 0.218 | 14 | 1 | 0.071 | 0 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0002768 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
| PRKCE | PRKCE | Q02156 | Protein kinase C epsilon type | chr2 | GO:0002768 | Not Cancer Driver | No | 107 | 0.145 | 170 | 26 | 0.153 | 0 |
| PRKCQ | PRKCQ | Q04759 | Protein kinase C theta type | chr10 | GO:0002768 | Not Cancer Driver | No | 147 | 0.208 | 28 | 9 | 0.321 | 0 |
| PSG9 | PSG9 | Q00887 | Pregnancy-specific beta-1-glycoprotein 9 | chr19 | GO:0002768 | Not Cancer Driver | No | 125 | 0.293 | 40 | 8 | 0.2 | 0 |
| PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0002768 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
| SOS1_ENST00000402219 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0002768 | Compendium | Yes | 197 | 0.148 | 458 | 62 | 0.135 | 38 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0002768 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0002768 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0002768 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TYROBP | TYROBP | O43914 | TYRO protein tyrosine kinase-binding protein | chr19 | GO:0002768 | Not Cancer Driver | No | 24 | 0.212 | 28 | 8 | 0.286 | 0 |
| VAV1 | VAV1 | P15498 | Proto-oncogene vav | chr19 | GO:0002768 | Census, Compendium | Yes | 165 | 0.195 | 113 | 19 | 0.168 | 0 |
| VAV2 | VAV2 | P52735 | Guanine nucleotide exchange factor VAV2 | chr9 | GO:0002768 | Not Cancer Driver | No | 127 | 0.145 | 135 | 17 | 0.126 | 0 |
| VAV3 | VAV3 | Q9UKW4 | Guanine nucleotide exchange factor VAV3 | chr1 | GO:0002768 | Not Cancer Driver | No | 153 | 0.181 | 102 | 18 | 0.176 | 0 |
| YES1_ENST00000314574 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | GO:0002768 | Not Cancer Driver | No | 65 | 0.12 | 62 | 10 | 0.161 | 0 |