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Total number of protein in "GO:0002708" GO term:  99

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0002708 Not Cancer Driver No 111 0.135 144 22 0.153 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0002708 Not Cancer Driver No 64 0.108 373 42 0.113 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0002708 Not Cancer Driver No 200 0.108 1075 112 0.104 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 GO:0002708 Not Cancer Driver No 59 0.198 41 10 0.244 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0002708 Census, Compendium Yes 34 0.286 5 1 0.2 2
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0002708 Census, Compendium Yes 147 0.223 114 27 0.237 110
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0002708 Not Cancer Driver No 16 0.06 84 3 0.036 0
C3 C3 P01024 Complement C3 chr19 GO:0002708 Not Cancer Driver No 337 0.203 287 50 0.174 12
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0002708 Not Cancer Driver No 106 0.24 103 28 0.272 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0002708 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD1A CD1A P06126 T-cell surface glycoprotein CD1a chr1 GO:0002708 Not Cancer Driver No 105 0.321 18 6 0.333 0
CD1B CD1B P29016 T-cell surface glycoprotein CD1b chr1 GO:0002708 Not Cancer Driver No 97 0.291 7 0 0.0 0
CD1C CD1C P29017 T-cell surface glycoprotein CD1c chr1 GO:0002708 Not Cancer Driver No 127 0.381 1 0 0.0 0
CD1D CD1D P15813 Antigen-presenting glycoprotein CD1d chr1 GO:0002708 Not Cancer Driver No 93 0.278 19 7 0.368 0
CD1E CD1E P15812 T-cell surface glycoprotein CD1e, membrane-associated chr1 GO:0002708 Not Cancer Driver No 158 0.407 21 11 0.524 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0002708 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0002708 Census Yes 42 0.191 18 10 0.556 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0002708 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0002708 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD81 CD81 P60033 CD81 antigen chr11 GO:0002708 Not Cancer Driver No 28 0.119 0 0 0.0 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0002708 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0002708 Not Cancer Driver No 85 0.199 320 73 0.228 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0002708 Not Cancer Driver No 64 0.163 135 14 0.104 0
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0002708 Not Cancer Driver No 69 0.089 299 19 0.064 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0002708 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0002708 Not Cancer Driver No 3 0.011 102 0 0.0 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0002708 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0002708 Not Cancer Driver No 53 0.164 78 11 0.141 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 GO:0002708 Not Cancer Driver No 133 0.112 440 48 0.109 1
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0002708 Not Cancer Driver No 41 0.128 130 22 0.169 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0002708 Not Cancer Driver No 38 0.088 186 16 0.086 10
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0002708 Not Cancer Driver No 45 0.077 58 4 0.069 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0002708 Census, Compendium Yes 111 0.251 364 87 0.239 2
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0002708 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0002708 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0002708 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0002708 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0002708 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0002708 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0002708 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0002708 Not Cancer Driver No 37 0.105 131 16 0.122 0
HPX HPX P02790 Hemopexin chr11 GO:0002708 Not Cancer Driver No 60 0.13 53 8 0.151 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0002708 Not Cancer Driver No 61 0.106 82 6 0.073 2
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0002708 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0002708 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0002708 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0002708 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0002708 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0002708 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0002708 Census Yes 24 0.157 6 1 0.167 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0002708 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0002708 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0002708 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0002708 Not Cancer Driver No 35 0.165 58 7 0.121 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0002708 Not Cancer Driver No 55 0.238 45 17 0.378 0
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0002708 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0002708 Not Cancer Driver No 37 0.08 142 9 0.063 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0002708 Not Cancer Driver No 47 0.113 93 10 0.108 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0002708 Not Cancer Driver No 37 0.18 20 5 0.25 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0002708 Not Cancer Driver No 22 0.104 0 0 0.0 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0002708 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0002708 Not Cancer Driver No 104 0.172 333 66 0.198 6
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0002708 Census Yes 92 0.122 208 22 0.106 85
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0002708 Not Cancer Driver No 60 0.176 33 7 0.212 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0002708 Census Yes 92 0.099 37 4 0.108 70
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0002708 Not Cancer Driver No 63 0.117 296 29 0.098 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0002708 Not Cancer Driver No 339 0.327 64 33 0.516 37
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0002708 Not Cancer Driver No 169 0.163 40 4 0.1 15
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0002708 Census, Compendium Yes 191 0.14 552 76 0.138 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0002708 Not Cancer Driver No 51 0.086 14 2 0.143 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0002708 Not Cancer Driver No 120 0.112 461 39 0.085 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0002708 Not Cancer Driver No 70 0.118 116 11 0.095 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0002708 Census, Compendium Yes 315 0.241 462 107 0.232 0
PVR PVR P15151 Poliovirus receptor chr19 GO:0002708 Not Cancer Driver No 39 0.094 120 19 0.158 0
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0002708 Not Cancer Driver No 41 0.123 62 10 0.161 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0002708 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0002708 Not Cancer Driver No 68 0.188 22 1 0.045 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0002708 Not Cancer Driver No 59 0.155 327 49 0.15 0
SH2D1B SH2D1B O14796 SH2 domain-containing protein 1B chr1 GO:0002708 Not Cancer Driver No 34 0.258 0 0 0.0 0
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0002708 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0002708 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0002708 Not Cancer Driver No 3 0.012 81 1 0.012 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0002708 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC22A13 SLC22A13 Q9Y226 Solute carrier family 22 member 13 chr3 GO:0002708 Not Cancer Driver No 55 0.1 32 3 0.094 0
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0002708 Census, Compendium Yes 106 0.125 325 44 0.135 0
STX7 STX7 O15400 Syntaxin-7 chr6 GO:0002708 Not Cancer Driver No 29 0.111 164 14 0.085 0
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0002708 Not Cancer Driver No 70 0.131 348 50 0.144 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0002708 Census Yes 89 0.117 80 6 0.075 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0002708 Not Cancer Driver No 41 0.105 41 4 0.098 10
TNF TNF P01375 Tumor necrosis factor chr6 GO:0002708 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0002708 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0002708 Not Cancer Driver No 28 0.153 1 0 0.0 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0002708 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0002708 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0002708 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0002708 Not Cancer Driver No 43 0.187 27 2 0.074 1
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0002708 Not Cancer Driver No 28 0.246 35 11 0.314 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0002708 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0002708 Not Cancer Driver No 55 0.13 56 11 0.196 1