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Total number of protein in "GO:0002703" GO term:  219

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADGRE2 ADGRE2 Q9UHX3 Adhesion G protein-coupled receptor E2 chr19 GO:0002703 Not Cancer Driver No 134 0.163 104 22 0.212 1
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0002703 Not Cancer Driver No 23 0.069 0 0 0.0 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0002703 Not Cancer Driver No 31 0.077 297 21 0.071 0
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0002703 Not Cancer Driver No 129 0.152 351 75 0.214 0
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0002703 Not Cancer Driver No 111 0.135 144 22 0.153 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0002703 Not Cancer Driver No 64 0.125 407 57 0.14 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0002703 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0002703 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0002703 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0002703 Not Cancer Driver No 200 0.108 1075 112 0.104 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 GO:0002703 Not Cancer Driver No 59 0.198 41 10 0.244 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0002703 Census, Compendium Yes 34 0.286 5 1 0.2 2
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0002703 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0002703 Census, Compendium Yes 146 0.115 603 69 0.114 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0002703 Not Cancer Driver No 94 0.186 75 21 0.28 0
BST2 BST2 Q10589 Bone marrow stromal antigen 2 chr19 GO:0002703 Not Cancer Driver No 19 0.106 20 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0002703 Census, Compendium Yes 147 0.223 114 27 0.237 110
C12orf4 C12orf4 Q9NQ89 Protein C12orf4 chr12 GO:0002703 Not Cancer Driver No 70 0.127 111 8 0.072 1
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0002703 Not Cancer Driver No 16 0.06 84 3 0.036 0
C3 C3 P01024 Complement C3 chr19 GO:0002703 Not Cancer Driver No 337 0.203 287 50 0.174 12
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 GO:0002703 Not Cancer Driver No 109 0.183 40 10 0.25 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 GO:0002703 Not Cancer Driver No 40 0.159 0 0 0.0 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0002703 Not Cancer Driver No 106 0.24 103 28 0.272 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0002703 Not Cancer Driver No 101 0.214 127 30 0.236 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0002703 Not Cancer Driver No 81 0.217 23 1 0.043 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0002703 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 GO:0002703 Not Cancer Driver No 71 0.162 79 26 0.329 0
CD1A CD1A P06126 T-cell surface glycoprotein CD1a chr1 GO:0002703 Not Cancer Driver No 105 0.321 18 6 0.333 0
CD1B CD1B P29016 T-cell surface glycoprotein CD1b chr1 GO:0002703 Not Cancer Driver No 97 0.291 7 0 0.0 0
CD1C CD1C P29017 T-cell surface glycoprotein CD1c chr1 GO:0002703 Not Cancer Driver No 127 0.381 1 0 0.0 0
CD1D CD1D P15813 Antigen-presenting glycoprotein CD1d chr1 GO:0002703 Not Cancer Driver No 93 0.278 19 7 0.368 0
CD1E CD1E P15812 T-cell surface glycoprotein CD1e, membrane-associated chr1 GO:0002703 Not Cancer Driver No 158 0.407 21 11 0.524 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0002703 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0002703 Census Yes 42 0.191 18 10 0.556 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0002703 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0002703 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0002703 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0002703 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD81 CD81 P60033 CD81 antigen chr11 GO:0002703 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0002703 Not Cancer Driver No 82 0.238 52 11 0.212 0
CD96 CD96 P40200 T-cell surface protein tactile chr3 GO:0002703 Not Cancer Driver No 132 0.226 165 34 0.206 1
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0002703 Not Cancer Driver No 64 0.122 241 25 0.104 0
CLC CLC Q05315 Galectin-10 chr19 GO:0002703 Not Cancer Driver No 29 0.204 0 0 0.0 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0002703 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 GO:0002703 Not Cancer Driver No 34 0.123 57 8 0.14 0
CLEC4G CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 GO:0002703 Not Cancer Driver No 40 0.137 35 4 0.114 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0002703 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0002703 Not Cancer Driver No 85 0.199 320 73 0.228 0
CR1L CR1L Q2VPA4 Complement component receptor 1-like protein chr1 GO:0002703 Not Cancer Driver No 121 0.213 55 14 0.255 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0002703 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0002703 Not Cancer Driver No 273 0.264 85 28 0.329 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0002703 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0002703 Not Cancer Driver No 64 0.163 135 14 0.104 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0002703 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL6 CXCL6 P80162 C-X-C motif chemokine 6 chr4 GO:0002703 Not Cancer Driver No 17 0.149 9 1 0.111 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0002703 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0002703 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0002703 Not Cancer Driver No 118 0.128 61 10 0.164 2
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0002703 Not Cancer Driver No 69 0.089 299 19 0.064 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0002703 Not Cancer Driver No 159 0.158 222 39 0.176 0
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0002703 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE1_ENST00000246949 DNASE1 P24855 Deoxyribonuclease-1 chr16 GO:0002703 Not Cancer Driver No 24 0.085 0 0 0.0 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0002703 Not Cancer Driver No 84 0.457 0 0 0.0 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0002703 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0002703 Not Cancer Driver No 3 0.011 102 0 0.0 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0002703 Not Cancer Driver No 55 0.139 7 2 0.286 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0002703 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0002703 Not Cancer Driver No 53 0.164 78 11 0.141 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 GO:0002703 Not Cancer Driver No 133 0.112 440 48 0.109 1
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0002703 Not Cancer Driver No 41 0.128 130 22 0.169 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0002703 Census Yes 51 0.165 99 30 0.303 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0002703 Not Cancer Driver No 114 0.139 145 21 0.145 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0002703 Census Yes 103 0.125 245 34 0.139 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0002703 Not Cancer Driver No 85 0.161 52 8 0.154 0
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0002703 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0002703 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0002703 Not Cancer Driver No 38 0.088 186 16 0.086 10
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0002703 Not Cancer Driver No 28 0.082 25 3 0.12 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0002703 Not Cancer Driver No 45 0.077 58 4 0.069 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 GO:0002703 Not Cancer Driver No 85 0.126 537 73 0.136 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0002703 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0002703 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0002703 Census, Compendium Yes 111 0.251 364 87 0.239 2
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0002703 Not Cancer Driver No 10 0.049 97 4 0.041 1
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0002703 Not Cancer Driver No 69 0.229 17 2 0.118 3
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0002703 Not Cancer Driver No 55 0.158 27 2 0.074 11
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0002703 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0002703 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0002703 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0002703 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0002703 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0002703 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0002703 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0002703 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0002703 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0002703 Not Cancer Driver No 46 0.16 81 13 0.16 0
HPX HPX P02790 Hemopexin chr11 GO:0002703 Not Cancer Driver No 60 0.13 53 8 0.151 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0002703 Not Cancer Driver No 61 0.106 82 6 0.073 2
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0002703 Not Cancer Driver No 61 0.115 251 28 0.112 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0002703 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0002703 Not Cancer Driver No 46 0.246 0 0 0.0 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0002703 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0002703 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0002703 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0002703 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX GO:0002703 Not Cancer Driver No 69 0.182 0 0 0.0 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0002703 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0002703 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0002703 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0002703 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0002703 Census Yes 24 0.157 6 1 0.167 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0002703 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0002703 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0002703 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0002703 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0002703 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0002703 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0002703 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0002703 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0002703 Census, Compendium Yes 177 0.386 88 48 0.545 1
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0002703 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0002703 Not Cancer Driver No 147 0.191 59 9 0.153 15
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0002703 Census, Compendium Yes 167 0.149 63 10 0.159 7
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0002703 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0002703 Not Cancer Driver No 49 0.21 49 10 0.204 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0002703 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0002703 Not Cancer Driver No 37 0.207 0 0 0.0 0
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0002703 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0002703 Not Cancer Driver No 37 0.08 142 9 0.063 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0002703 Not Cancer Driver No 47 0.113 93 10 0.108 0
LEP LEP P41159 Leptin chr7 GO:0002703 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0002703 Not Cancer Driver No 54 0.152 65 16 0.246 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0002703 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0002703 Not Cancer Driver No 162 0.362 277 115 0.415 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0002703 Not Cancer Driver No 37 0.18 20 5 0.25 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0002703 Census Yes 95 0.186 84 12 0.143 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0002703 Not Cancer Driver No 22 0.104 0 0 0.0 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0002703 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0002703 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0002703 Not Cancer Driver No 70 0.13 411 58 0.141 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0002703 Census Yes 92 0.122 208 22 0.106 85
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0002703 Not Cancer Driver No 60 0.176 33 7 0.212 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0002703 Census Yes 92 0.099 37 4 0.108 70
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0002703 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCR1 NCR1 O76036 Natural cytotoxicity triggering receptor 1 chr19 GO:0002703 Not Cancer Driver No 81 0.266 27 8 0.296 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0002703 Not Cancer Driver No 22 0.1 44 4 0.091 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0002703 Not Cancer Driver No 63 0.117 296 29 0.098 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0002703 Not Cancer Driver No 339 0.327 64 33 0.516 37
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0002703 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0002703 Not Cancer Driver No 207 0.18 201 33 0.164 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0002703 Census, Compendium Yes 191 0.14 552 76 0.138 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0002703 Not Cancer Driver No 51 0.086 14 2 0.143 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0002703 Not Cancer Driver No 70 0.131 269 38 0.141 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0002703 Not Cancer Driver No 120 0.112 461 39 0.085 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0002703 Not Cancer Driver No 33 0.059 121 12 0.099 0
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 GO:0002703 Not Cancer Driver No 100 0.133 156 26 0.167 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0002703 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0002703 Not Cancer Driver No 248 0.196 142 30 0.211 1
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0002703 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRAM1 PRAM1 Q96QH2 PML-RARA-regulated adapter molecule 1 chr19 GO:0002703 Not Cancer Driver No 118 0.176 628 117 0.186 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0002703 Not Cancer Driver No 70 0.118 116 11 0.095 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0002703 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0002703 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0002703 Census, Compendium Yes 315 0.241 462 107 0.232 0
PVR PVR P15151 Poliovirus receptor chr19 GO:0002703 Not Cancer Driver No 39 0.094 120 19 0.158 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0002703 Not Cancer Driver No 73 0.149 175 35 0.2 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0002703 Not Cancer Driver No 31 0.161 0 0 0.0 2
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0002703 Not Cancer Driver No 41 0.123 62 10 0.161 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0002703 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0002703 Not Cancer Driver No 66 0.127 295 39 0.132 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0002703 Not Cancer Driver No 68 0.188 22 1 0.045 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0002703 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0002703 Not Cancer Driver No 10 0.069 73 9 0.123 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 GO:0002703 Not Cancer Driver No 120 0.308 48 18 0.375 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0002703 Not Cancer Driver No 64 0.17 22 2 0.091 0
SH2D1B SH2D1B O14796 SH2 domain-containing protein 1B chr1 GO:0002703 Not Cancer Driver No 34 0.258 0 0 0.0 0
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0002703 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0002703 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0002703 Not Cancer Driver No 3 0.012 81 1 0.012 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0002703 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 GO:0002703 Not Cancer Driver No 66 0.114 23 4 0.174 0
SLC22A13 SLC22A13 Q9Y226 Solute carrier family 22 member 13 chr3 GO:0002703 Not Cancer Driver No 55 0.1 32 3 0.094 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0002703 Not Cancer Driver No 40 0.094 139 0 0.0 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0002703 Not Cancer Driver No 31 0.069 101 5 0.05 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0002703 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0002703 Not Cancer Driver No 46 0.17 187 34 0.182 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0002703 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0002703 Census, Compendium Yes 106 0.125 325 44 0.135 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0002703 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX7 STX7 O15400 Syntaxin-7 chr6 GO:0002703 Not Cancer Driver No 29 0.111 164 14 0.085 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0002703 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0002703 Not Cancer Driver No 77 0.13 80 13 0.163 5
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 GO:0002703 Not Cancer Driver No 222 0.129 761 107 0.141 0
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 GO:0002703 Not Cancer Driver No 85 0.173 134 27 0.201 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0002703 Census Yes 96 0.151 131 27 0.206 5
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0002703 Not Cancer Driver No 70 0.131 348 50 0.144 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0002703 Census Yes 89 0.117 80 6 0.075 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0002703 Not Cancer Driver No 41 0.105 41 4 0.098 10
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:0002703 Not Cancer Driver No 55 0.084 280 26 0.093 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0002703 Not Cancer Driver No 92 0.129 443 66 0.149 1
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0002703 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0002703 Not Cancer Driver No 292 0.348 0 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0002703 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0002703 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0002703 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0002703 Not Cancer Driver No 28 0.153 1 0 0.0 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0002703 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0002703 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0002703 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0002703 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0002703 Not Cancer Driver No 152 0.125 149 18 0.121 12
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0002703 Not Cancer Driver No 24 0.212 28 8 0.286 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0002703 Not Cancer Driver No 120 0.11 248 30 0.121 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0002703 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0002703 Not Cancer Driver No 9 0.09 27 0 0.0 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0002703 Census, Compendium Yes 75 0.149 400 55 0.138 30
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0002703 Not Cancer Driver No 28 0.246 35 11 0.314 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0002703 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0002703 Not Cancer Driver No 55 0.13 56 11 0.196 1