Total number of protein in "GO:0002690" GO term: 89
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM10 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | GO:0002690 | Not Cancer Driver | No | 88 | 0.118 | 156 | 20 | 0.128 | 4 |
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0002690 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| AIF1 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | GO:0002690 | Not Cancer Driver | No | 14 | 0.095 | 61 | 6 | 0.098 | 0 |
| AKIRIN1 | AKIRIN1 | Q9H9L7 | Akirin-1 | chr1 | GO:0002690 | Not Cancer Driver | No | 11 | 0.057 | 125 | 9 | 0.072 | 0 |
| ANO6_ENST00000320560 | ANO6 | Q4KMQ2 | Anoctamin-6 | chr12 | GO:0002690 | Not Cancer Driver | No | 134 | 0.147 | 80 | 11 | 0.138 | 0 |
| C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | GO:0002690 | Not Cancer Driver | No | 14 | 0.05 | 103 | 6 | 0.058 | 2 |
| C3AR1 | C3AR1 | Q16581 | C3a anaphylatoxin chemotactic receptor | chr12 | GO:0002690 | Not Cancer Driver | No | 88 | 0.183 | 72 | 16 | 0.222 | 0 |
| C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | GO:0002690 | Not Cancer Driver | No | 71 | 0.203 | 0 | 0 | 0.0 | 0 |
| CALR | CALR | P27797 | Calreticulin | chr19 | GO:0002690 | Census | Yes | 45 | 0.108 | 245 | 31 | 0.127 | 0 |
| CAMK1D | CAMK1D | Q8IU85 | Calcium/calmodulin-dependent protein kinase type 1D | chr10 | GO:0002690 | Not Cancer Driver | No | 90 | 0.234 | 42 | 14 | 0.333 | 0 |
| CCL1 | CCL1 | P22362 | C-C motif chemokine 1 | chr17 | GO:0002690 | Not Cancer Driver | No | 27 | 0.281 | 0 | 0 | 0.0 | 0 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0002690 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CCL21 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0002690 | Not Cancer Driver | No | 14 | 0.104 | 59 | 6 | 0.102 | 0 |
| CCL27 | CCL27 | Q9Y4X3 | C-C motif chemokine 27 | chr9 | GO:0002690 | Not Cancer Driver | No | 15 | 0.134 | 0 | 0 | 0.0 | 0 |
| CCL7 | CCL7 | P80098 | C-C motif chemokine 7 | chr17 | GO:0002690 | Not Cancer Driver | No | 30 | 0.303 | 13 | 3 | 0.231 | 0 |
| CCR1 | CCR1 | P32246 | C-C chemokine receptor type 1 | chr3 | GO:0002690 | Not Cancer Driver | No | 69 | 0.194 | 14 | 5 | 0.357 | 0 |
| CCR2_ENST00000400888 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:0002690 | Not Cancer Driver | No | 81 | 0.217 | 23 | 1 | 0.043 | 0 |
| CCR6_ENST00000349984 | CCR6 | P51684 | C-C chemokine receptor type 6 | chr6 | GO:0002690 | Not Cancer Driver | No | 56 | 0.15 | 13 | 2 | 0.154 | 0 |
| CCR7 | CCR7 | P32248 | C-C chemokine receptor type 7 | chr17 | GO:0002690 | Census, Compendium | Yes | 50 | 0.132 | 0 | 0 | 0.0 | 0 |
| CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0002690 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
| CMKLR1 | CMKLR1 | Q99788 | Chemerin-like receptor 1 | chr12 | GO:0002690 | Not Cancer Driver | No | 107 | 0.287 | 24 | 13 | 0.542 | 0 |
| CREB3 | CREB3 | O43889 | Cyclic AMP-responsive element-binding protein 3 | chr9 | GO:0002690 | Not Cancer Driver | No | 33 | 0.089 | 168 | 11 | 0.065 | 0 |
| CSF1R | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0002690 | Census | Yes | 133 | 0.137 | 124 | 17 | 0.137 | 20 |
| CSF1_ENST00000369802 | CSF1 | P09603 | Macrophage colony-stimulating factor 1 | chr1 | GO:0002690 | Not Cancer Driver | No | 69 | 0.125 | 339 | 46 | 0.136 | 0 |
| CX3CR1_ENST00000542107 | CX3CR1 | P49238 | CX3C chemokine receptor 1 | chr3 | GO:0002690 | Not Cancer Driver | No | 80 | 0.225 | 0 | 0 | 0.0 | 0 |
| CXCL10 | CXCL10 | P02778 | C-X-C motif chemokine 10 | chr4 | GO:0002690 | Not Cancer Driver | No | 19 | 0.194 | 12 | 4 | 0.333 | 0 |
| CXCL12_ENST00000374429 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:0002690 | Not Cancer Driver | No | 16 | 0.172 | 0 | 0 | 0.0 | 0 |
| CXCL13 | CXCL13 | O43927 | C-X-C motif chemokine 13 | chr4 | GO:0002690 | Not Cancer Driver | No | 11 | 0.101 | 0 | 0 | 0.0 | 0 |
| CXCL17 | CXCL17 | Q6UXB2 | C-X-C motif chemokine 17 | chr19 | GO:0002690 | Not Cancer Driver | No | 8 | 0.067 | 44 | 6 | 0.136 | 0 |
| CXCL8 | CXCL8 | P10145 | Interleukin-8 | chr4 | GO:0002690 | Not Cancer Driver | No | 17 | 0.172 | 0 | 0 | 0.0 | 0 |
| DAPK2 | DAPK2 | Q9UIK4 | Death-associated protein kinase 2 | chr15 | GO:0002690 | Not Cancer Driver | No | 55 | 0.149 | 53 | 9 | 0.17 | 0 |
| DEFB124 | DEFB124 | Q8NES8 | Beta-defensin 124 | chr20 | GO:0002690 | Not Cancer Driver | No | 9 | 0.127 | 3 | 0 | 0.0 | 0 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | GO:0002690 | Not Cancer Driver | No | 67 | 0.091 | 212 | 23 | 0.108 | 7 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0002690 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EDN2 | EDN2 | P20800 | Endothelin-2 | chr1 | GO:0002690 | Not Cancer Driver | No | 21 | 0.118 | 87 | 13 | 0.149 | 0 |
| EDN3_ENST00000371028 | EDN3 | P14138 | Endothelin-3 | chr20 | GO:0002690 | Not Cancer Driver | No | 69 | 0.29 | 140 | 44 | 0.314 | 3 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0002690 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
| F7 | F7 | P08709 | Coagulation factor VII | chr13 | GO:0002690 | Not Cancer Driver | No | 74 | 0.159 | 50 | 7 | 0.14 | 108 |
| FPR2 | FPR2 | P25090 | N-formyl peptide receptor 2 | chr19 | GO:0002690 | Not Cancer Driver | No | 96 | 0.274 | 26 | 5 | 0.192 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0002690 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GPSM3_ENST00000375043 | GPSM3 | Q9Y4H4 | G-protein-signaling modulator 3 | chr6 | GO:0002690 | Not Cancer Driver | No | 26 | 0.163 | 160 | 26 | 0.163 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0002690 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| IL23A | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:0002690 | Not Cancer Driver | No | 15 | 0.079 | 42 | 3 | 0.071 | 0 |
| IL34 | IL34 | Q6ZMJ4 | Interleukin-34 | chr16 | GO:0002690 | Not Cancer Driver | No | 22 | 0.091 | 42 | 6 | 0.143 | 0 |
| IL4 | IL4 | P05112 | Interleukin-4 | chr5 | GO:0002690 | Not Cancer Driver | No | 18 | 0.118 | 0 | 0 | 0.0 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0002690 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IL6R | IL6R | P08887 | Interleukin-6 receptor subunit alpha | chr1 | GO:0002690 | Not Cancer Driver | No | 55 | 0.118 | 165 | 23 | 0.139 | 1 |
| LBP | LBP | P18428 | Lipopolysaccharide-binding protein | chr20 | GO:0002690 | Not Cancer Driver | No | 84 | 0.175 | 6 | 0 | 0.0 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0002690 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| LGMN_ENST00000334869 | LGMN | Q99538 | Legumain | chr14 | GO:0002690 | Not Cancer Driver | No | 57 | 0.132 | 112 | 19 | 0.17 | 0 |
| MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | GO:0002690 | Census, Compendium | Yes | 62 | 0.172 | 2 | 0 | 0.0 | 7 |
| MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0002690 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
| MCU | MCU | Q8NE86 | Calcium uniporter protein, mitochondrial | chr10 | GO:0002690 | Not Cancer Driver | No | 41 | 0.117 | 13 | 0 | 0.0 | 0 |
| MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0002690 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
| MOSPD2 | MOSPD2 | Q8NHP6 | Motile sperm domain-containing protein 2 | chrX | GO:0002690 | Not Cancer Driver | No | 58 | 0.112 | 143 | 16 | 0.112 | 0 |
| MSTN | MSTN | O14793 | Growth/differentiation factor 8 | chr2 | GO:0002690 | Not Cancer Driver | No | 68 | 0.181 | 64 | 11 | 0.172 | 0 |
| NCKAP1L | NCKAP1L | P55160 | Nck-associated protein 1-like | chr12 | GO:0002690 | Not Cancer Driver | No | 247 | 0.219 | 51 | 10 | 0.196 | 4 |
| OXSR1 | OXSR1 | O95747 | Serine/threonine-protein kinase OSR1 | chr3 | GO:0002690 | Not Cancer Driver | No | 69 | 0.131 | 208 | 29 | 0.139 | 0 |
| PGF_ENST00000405431 | PGF | P49763 | Placenta growth factor | chr14 | GO:0002690 | Not Cancer Driver | No | 30 | 0.136 | 72 | 10 | 0.139 | 0 |
| PLA2G7 | PLA2G7 | Q13093 | Platelet-activating factor acetylhydrolase | chr6 | GO:0002690 | Not Cancer Driver | No | 70 | 0.159 | 27 | 7 | 0.259 | 2 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0002690 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0002690 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0002690 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0002690 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | GO:0002690 | Not Cancer Driver | No | 31 | 0.161 | 0 | 0 | 0.0 | 2 |
| RARRES2 | RARRES2 | Q99969 | Retinoic acid receptor responder protein 2 | chr7 | GO:0002690 | Not Cancer Driver | No | 16 | 0.098 | 14 | 2 | 0.143 | 0 |
| RIPOR2_ENST00000259698 | RIPOR2 | Q9Y4F9 | Rho family-interacting cell polarization regulator 2 | chr6 | GO:0002690 | Not Cancer Driver | No | 131 | 0.123 | 421 | 76 | 0.181 | 0 |
| S100A14_ENST00000368701 | S100A14 | Q9HCY8 | Protein S100-A14 | chr1 | GO:0002690 | Not Cancer Driver | No | 15 | 0.144 | 55 | 9 | 0.164 | 0 |
| S100A7_ENST00000368722 | S100A7 | P31151 | Protein S100-A7 | chr1 | GO:0002690 | Census | Yes | 39 | 0.386 | 28 | 14 | 0.5 | 0 |
| SERPINE1 | SERPINE1 | P05121 | Plasminogen activator inhibitor 1 | chr7 | GO:0002690 | Not Cancer Driver | No | 78 | 0.194 | 7 | 2 | 0.286 | 0 |
| SLAMF1_ENST00000302035 | SLAMF1 | Q13291 | Signaling lymphocytic activation molecule | chr1 | GO:0002690 | Not Cancer Driver | No | 82 | 0.245 | 64 | 10 | 0.156 | 0 |
| SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0002690 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
| STK39 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0002690 | Not Cancer Driver | No | 64 | 0.117 | 182 | 19 | 0.104 | 0 |
| SWAP70 | SWAP70 | Q9UH65 | Switch-associated protein 70 | chr11 | GO:0002690 | Not Cancer Driver | No | 44 | 0.075 | 271 | 18 | 0.066 | 0 |
| THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0002690 | Not Cancer Driver | No | 188 | 0.161 | 320 | 58 | 0.181 | 0 |
| THBS4 | THBS4 | P35443 | Thrombospondin-4 | chr5 | GO:0002690 | Not Cancer Driver | No | 137 | 0.143 | 281 | 40 | 0.142 | 0 |
| TIRAP_ENST00000392680 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0002690 | Not Cancer Driver | No | 28 | 0.127 | 80 | 6 | 0.075 | 0 |
| TMEM102 | TMEM102 | Q8N9M5 | Transmembrane protein 102 | chr17 | GO:0002690 | Not Cancer Driver | No | 38 | 0.075 | 141 | 13 | 0.092 | 0 |
| TNFSF14 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:0002690 | Not Cancer Driver | No | 58 | 0.242 | 18 | 1 | 0.056 | 0 |
| TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0002690 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0002690 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| VEGFB | VEGFB | P49765 | Vascular endothelial growth factor B | chr11 | GO:0002690 | Not Cancer Driver | No | 25 | 0.121 | 125 | 22 | 0.176 | 0 |
| VEGFC | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0002690 | Not Cancer Driver | No | 128 | 0.305 | 37 | 12 | 0.324 | 0 |
| VEGFD | VEGFD | O43915 | Vascular endothelial growth factor D | chrX | GO:0002690 | Not Cancer Driver | No | 59 | 0.167 | 33 | 6 | 0.182 | 0 |
| WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | GO:0002690 | Not Cancer Driver | No | 278 | 0.117 | 1959 | 223 | 0.114 | 0 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0002690 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| XCL1 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0002690 | Not Cancer Driver | No | 28 | 0.246 | 35 | 11 | 0.314 | 0 |
| XCL2 | XCL2 | Q9UBD3 | Cytokine SCM-1 beta | chr1 | GO:0002690 | Not Cancer Driver | No | 20 | 0.175 | 35 | 5 | 0.143 | 0 |
| ZNF580_ENST00000545125 | ZNF580 | Q9UK33 | Zinc finger protein 580 | chr19 | GO:0002690 | Not Cancer Driver | No | 8 | 0.047 | 153 | 8 | 0.052 | 0 |