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Total number of protein in "GO:0002687" GO term:  126

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0002687 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0002687 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0002687 Not Cancer Driver No 82 0.1 230 13 0.057 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0002687 Not Cancer Driver No 31 0.077 297 21 0.071 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0002687 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKIRIN1 AKIRIN1 Q9H9L7 Akirin-1 chr1 GO:0002687 Not Cancer Driver No 11 0.057 125 9 0.072 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0002687 Not Cancer Driver No 134 0.147 80 11 0.138 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0002687 Not Cancer Driver No 128 0.166 418 71 0.17 17
BDKRB1_ENST00000611804 BDKRB1 P46663 B1 bradykinin receptor chr14 GO:0002687 Not Cancer Driver No 68 0.193 3 0 0.0 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0002687 Not Cancer Driver No 14 0.05 103 6 0.058 2
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0002687 Not Cancer Driver No 88 0.183 72 16 0.222 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0002687 Not Cancer Driver No 71 0.203 0 0 0.0 0
CALR CALR P27797 Calreticulin chr19 GO:0002687 Census Yes 45 0.108 245 31 0.127 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:0002687 Not Cancer Driver No 90 0.234 42 14 0.333 0
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0002687 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0002687 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL20 CCL20 P78556 C-C motif chemokine 20 chr2 GO:0002687 Not Cancer Driver No 16 0.167 0 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0002687 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0002687 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL27 CCL27 Q9Y4X3 C-C motif chemokine 27 chr9 GO:0002687 Not Cancer Driver No 15 0.134 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0002687 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCL8 CCL8 P80075 C-C motif chemokine 8 chr17 GO:0002687 Not Cancer Driver No 17 0.172 0 0 0.0 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0002687 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0002687 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0002687 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0002687 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0002687 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0002687 Census Yes 31 0.105 185 20 0.108 0
CD99 CD99 P14209 CD99 antigen chrX GO:0002687 Not Cancer Driver No 22 0.119 143 19 0.133 0
CD99L2_ENST00000370377 CD99L2 Q8TCZ2 CD99 antigen-like protein 2 chrX GO:0002687 Not Cancer Driver No 57 0.218 193 47 0.244 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0002687 Not Cancer Driver No 107 0.287 24 13 0.542 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0002687 Not Cancer Driver No 33 0.089 168 11 0.065 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0002687 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0002687 Not Cancer Driver No 69 0.125 339 46 0.136 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0002687 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0002687 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0002687 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0002687 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0002687 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL17 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0002687 Not Cancer Driver No 8 0.067 44 6 0.136 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0002687 Not Cancer Driver No 17 0.172 0 0 0.0 0
DAPK2 DAPK2 Q9UIK4 Death-associated protein kinase 2 chr15 GO:0002687 Not Cancer Driver No 55 0.149 53 9 0.17 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0002687 Not Cancer Driver No 9 0.127 3 0 0.0 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0002687 Not Cancer Driver No 67 0.091 212 23 0.108 7
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0002687 Not Cancer Driver No 321 0.153 312 60 0.192 1
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0002687 Not Cancer Driver No 37 0.175 97 20 0.206 3
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0002687 Not Cancer Driver No 26 0.125 45 10 0.222 1
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0002687 Not Cancer Driver No 96 0.274 26 5 0.192 0
FUT4 FUT4 P22083 Alpha-(1,3)-fucosyltransferase 4 chr11 GO:0002687 Not Cancer Driver No 49 0.092 193 9 0.047 0
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0002687 Not Cancer Driver No 28 0.082 25 3 0.12 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0002687 Not Cancer Driver No 82 0.121 42 6 0.143 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0002687 Not Cancer Driver No 25 0.116 203 20 0.099 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0002687 Not Cancer Driver No 61 0.115 251 28 0.112 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0002687 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0002687 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0002687 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0002687 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0002687 Not Cancer Driver No 18 0.118 0 0 0.0 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0002687 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0002687 Not Cancer Driver No 254 0.246 97 27 0.278 0
JAM2_ENST00000480456 JAM2 P57087 Junctional adhesion molecule B chr21 GO:0002687 Not Cancer Driver No 63 0.211 64 16 0.25 2
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0002687 Not Cancer Driver No 50 0.161 62 11 0.177 2
KITLG KITLG P21583 Kit ligand chr12 GO:0002687 Not Cancer Driver No 48 0.176 61 9 0.148 1
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0002687 Not Cancer Driver No 84 0.175 6 0 0.0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0002687 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0002687 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0002687 Not Cancer Driver No 57 0.132 112 19 0.17 0
LYVE1 LYVE1 Q9Y5Y7 Lymphatic vessel endothelial hyaluronic acid receptor 1 chr11 GO:0002687 Not Cancer Driver No 34 0.106 77 13 0.169 0
MADCAM1 MADCAM1 Q13477 Mucosal addressin cell adhesion molecule 1 chr19 GO:0002687 Not Cancer Driver No 39 0.102 240 33 0.138 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0002687 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0002687 Not Cancer Driver No 38 0.1 49 5 0.102 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0002687 Not Cancer Driver No 41 0.117 13 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0002687 Not Cancer Driver No 15 0.105 20 2 0.1 0
MIA3 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 GO:0002687 Not Cancer Driver No 222 0.116 1490 178 0.119 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0002687 Not Cancer Driver No 64 0.11 118 11 0.093 1
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX GO:0002687 Not Cancer Driver No 58 0.112 143 16 0.112 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0002687 Not Cancer Driver No 68 0.181 64 11 0.172 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0002687 Not Cancer Driver No 247 0.219 51 10 0.196 4
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0002687 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0002687 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0002687 Not Cancer Driver No 57 0.167 21 2 0.095 3
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0002687 Not Cancer Driver No 85 0.23 37 13 0.351 0
PGF_ENST00000405431 PGF P49763 Placenta growth factor chr14 GO:0002687 Not Cancer Driver No 30 0.136 72 10 0.139 0
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0002687 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLVAP PLVAP Q9BX97 Plasmalemma vesicle-associated protein chr19 GO:0002687 Not Cancer Driver No 96 0.217 174 39 0.224 1
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0002687 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0002687 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0002687 Not Cancer Driver No 134 0.127 425 55 0.129 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0002687 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0002687 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0002687 Not Cancer Driver No 31 0.161 0 0 0.0 2
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0002687 Not Cancer Driver No 16 0.098 14 2 0.143 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0002687 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0002687 Not Cancer Driver No 131 0.123 421 76 0.181 0
S100A14_ENST00000368701 S100A14 Q9HCY8 Protein S100-A14 chr1 GO:0002687 Not Cancer Driver No 15 0.144 55 9 0.164 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0002687 Census Yes 39 0.386 28 14 0.5 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0002687 Not Cancer Driver No 10 0.106 47 6 0.128 0
SELP SELP P16109 P-selectin chr1 GO:0002687 Not Cancer Driver No 226 0.272 14 2 0.143 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0002687 Not Cancer Driver No 78 0.194 7 2 0.286 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0002687 Not Cancer Driver No 82 0.245 64 10 0.156 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0002687 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0002687 Not Cancer Driver No 46 0.115 357 35 0.098 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0002687 Not Cancer Driver No 64 0.117 182 19 0.104 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0002687 Not Cancer Driver No 44 0.075 271 18 0.066 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0002687 Not Cancer Driver No 69 0.17 28 2 0.071 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0002687 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 GO:0002687 Not Cancer Driver No 137 0.143 281 40 0.142 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0002687 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0002687 Not Cancer Driver No 28 0.127 80 6 0.075 0
TMEM102 TMEM102 Q8N9M5 Transmembrane protein 102 chr17 GO:0002687 Not Cancer Driver No 38 0.075 141 13 0.092 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0002687 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0002687 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF18_ENST00000379268 TNFRSF18 Q9Y5U5 Tumor necrosis factor receptor superfamily member 18 chr1 GO:0002687 Not Cancer Driver No 22 0.091 23 1 0.043 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0002687 Not Cancer Driver No 58 0.242 18 1 0.056 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0002687 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0002687 Not Cancer Driver No 142 0.163 231 34 0.147 44
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0002687 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFB VEGFB P49765 Vascular endothelial growth factor B chr11 GO:0002687 Not Cancer Driver No 25 0.121 125 22 0.176 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0002687 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0002687 Not Cancer Driver No 59 0.167 33 6 0.182 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0002687 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0002687 Not Cancer Driver No 66 0.174 0 0 0.0 2
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0002687 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0002687 Not Cancer Driver No 20 0.175 35 5 0.143 0
XG_ENST00000381174 XG P55808 Glycoprotein Xg chrX GO:0002687 Not Cancer Driver No 27 0.15 140 23 0.164 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0002687 Not Cancer Driver No 55 0.13 56 11 0.196 1