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Total number of protein in "GO:0002684" GO term:  616

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0002684 Census, Compendium Yes 139 0.123 604 73 0.121 2
AC136428.1 IGHV3OR16-17 S4R3C0 Immunoglobulin heavy variable 3/OR16-17 (non-functional) (Fragment) chr16 GO:0002684 Not Cancer Driver No 42 0.362 0 0 0.0 0
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 GO:0002684 Not Cancer Driver No 157 0.117 1294 155 0.12 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0002684 Not Cancer Driver No 5 0.01 36 0 0.0 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0002684 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0002684 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0002684 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0002684 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADGRE2 ADGRE2 Q9UHX3 Adhesion G protein-coupled receptor E2 chr19 GO:0002684 Not Cancer Driver No 134 0.163 104 22 0.212 1
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0002684 Not Cancer Driver No 23 0.069 0 0 0.0 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0002684 Not Cancer Driver No 31 0.077 297 21 0.071 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0002684 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKIRIN1 AKIRIN1 Q9H9L7 Akirin-1 chr1 GO:0002684 Not Cancer Driver No 11 0.057 125 9 0.072 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0002684 Census, Compendium Yes 108 0.225 158 24 0.152 4
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0002684 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 GO:0002684 Not Cancer Driver No 312 0.12 1790 221 0.123 9
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0002684 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0002684 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0002684 Not Cancer Driver No 111 0.135 144 22 0.153 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0002684 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0002684 Not Cancer Driver No 138 0.12 404 59 0.146 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0002684 Not Cancer Driver No 73 0.327 0 0 0.0 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0002684 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0002684 Not Cancer Driver No 70 0.105 149 14 0.094 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0002684 Not Cancer Driver No 34 0.116 12 0 0.0 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0002684 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0002684 Not Cancer Driver No 64 0.108 373 42 0.113 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0002684 Not Cancer Driver No 200 0.108 1075 112 0.104 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0002684 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 GO:0002684 Not Cancer Driver No 59 0.198 41 10 0.244 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0002684 Census, Compendium Yes 34 0.286 5 1 0.2 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0002684 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0002684 Census Yes 30 0.156 39 2 0.051 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0002684 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0002684 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0002684 Census, Compendium Yes 134 0.19 328 67 0.204 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0002684 Not Cancer Driver No 94 0.186 75 21 0.28 0
BLOC1S3 BLOC1S3 Q6QNY0 Biogenesis of lysosome-related organelles complex 1 subunit 3 chr19 GO:0002684 Not Cancer Driver No 3 0.015 148 2 0.014 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0002684 Not Cancer Driver No 12 0.07 111 11 0.099 0
BST1 BST1 Q10588 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 chr4 GO:0002684 Not Cancer Driver No 40 0.126 11 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0002684 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0002684 Not Cancer Driver No 92 0.176 24 2 0.083 0
C12orf4 C12orf4 Q9NQ89 Protein C12orf4 chr12 GO:0002684 Not Cancer Driver No 70 0.127 111 8 0.072 1
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0002684 Not Cancer Driver No 16 0.06 84 3 0.036 0
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 GO:0002684 Not Cancer Driver No 41 0.167 124 16 0.129 0
C1QB C1QB P02746 Complement C1q subcomponent subunit B chr1 GO:0002684 Not Cancer Driver No 46 0.182 133 31 0.233 1
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0002684 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QC C1QC P02747 Complement C1q subcomponent subunit C chr1 GO:0002684 Not Cancer Driver No 46 0.188 134 26 0.194 1
C1R C1R P00736 Complement C1r subcomponent chr12 GO:0002684 Not Cancer Driver No 88 0.125 51 6 0.118 6
C1RL C1RL Q9NZP8 Complement C1r subcomponent-like protein chr12 GO:0002684 Not Cancer Driver No 60 0.123 146 22 0.151 0
C1S C1S P09871 Complement C1s subcomponent chr12 GO:0002684 Not Cancer Driver No 128 0.186 97 21 0.216 1
C2 C2 P06681 Complement C2 chr6 GO:0002684 Not Cancer Driver No 120 0.16 120 17 0.142 3
C3 C3 P01024 Complement C3 chr19 GO:0002684 Not Cancer Driver No 337 0.203 287 50 0.174 12
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0002684 Not Cancer Driver No 88 0.183 72 16 0.222 0
C4A C4A P0C0L4 Complement C4-A chr6 GO:0002684 Not Cancer Driver No 43 0.025 309 6 0.019 0
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 GO:0002684 Not Cancer Driver No 109 0.183 40 10 0.25 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 GO:0002684 Not Cancer Driver No 40 0.159 0 0 0.0 0
C5 C5 P01031 Complement C5 chr9 GO:0002684 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0002684 Not Cancer Driver No 71 0.203 0 0 0.0 0
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 GO:0002684 Not Cancer Driver No 60 0.178 11 3 0.273 0
C6 C6 P13671 Complement component C6 chr5 GO:0002684 Not Cancer Driver No 346 0.37 121 47 0.388 0
C7 C7 P10643 Complement component C7 chr5 GO:0002684 Not Cancer Driver No 291 0.345 89 37 0.416 5
C8A C8A P07357 Complement component C8 alpha chain chr1 GO:0002684 Not Cancer Driver No 176 0.301 25 9 0.36 0
C8B C8B P07358 Complement component C8 beta chain chr1 GO:0002684 Not Cancer Driver No 186 0.315 29 11 0.379 0
C8G C8G P07360 Complement component C8 gamma chain chr9 GO:0002684 Not Cancer Driver No 10 0.05 26 2 0.077 0
C9 C9 P02748 Complement component C9 chr5 GO:0002684 Not Cancer Driver No 156 0.279 40 8 0.2 2
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0002684 Not Cancer Driver No 106 0.24 103 28 0.272 0
CALR CALR P27797 Calreticulin chr19 GO:0002684 Census Yes 45 0.108 245 31 0.127 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:0002684 Not Cancer Driver No 90 0.234 42 14 0.333 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0002684 Not Cancer Driver No 101 0.214 127 30 0.236 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0002684 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0002684 Not Cancer Driver No 72 0.134 225 35 0.156 11
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0002684 Census, Compendium Yes 142 0.296 106 12 0.113 1
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0002684 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0002684 Census, Compendium Yes 39 0.214 94 17 0.181 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0002684 Census Yes 160 0.163 562 104 0.185 0
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0002684 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0002684 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL20 CCL20 P78556 C-C motif chemokine 20 chr2 GO:0002684 Not Cancer Driver No 16 0.167 0 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0002684 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0002684 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL27 CCL27 Q9Y4X3 C-C motif chemokine 27 chr9 GO:0002684 Not Cancer Driver No 15 0.134 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0002684 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0002684 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0002684 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0002684 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0002684 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0002684 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 GO:0002684 Not Cancer Driver No 71 0.162 79 26 0.329 0
CD1A CD1A P06126 T-cell surface glycoprotein CD1a chr1 GO:0002684 Not Cancer Driver No 105 0.321 18 6 0.333 0
CD1B CD1B P29016 T-cell surface glycoprotein CD1b chr1 GO:0002684 Not Cancer Driver No 97 0.291 7 0 0.0 0
CD1C CD1C P29017 T-cell surface glycoprotein CD1c chr1 GO:0002684 Not Cancer Driver No 127 0.381 1 0 0.0 0
CD1D CD1D P15813 Antigen-presenting glycoprotein CD1d chr1 GO:0002684 Not Cancer Driver No 93 0.278 19 7 0.368 0
CD1E CD1E P15812 T-cell surface glycoprotein CD1e, membrane-associated chr1 GO:0002684 Not Cancer Driver No 158 0.407 21 11 0.524 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0002684 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0002684 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0002684 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0002684 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0002684 Census Yes 29 0.1 54 9 0.167 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0002684 Census Yes 42 0.191 18 10 0.556 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0002684 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD320 CD320 Q9NPF0 CD320 antigen chr19 GO:0002684 Not Cancer Driver No 30 0.106 82 9 0.11 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0002684 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0002684 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0002684 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0002684 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0002684 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD40LG CD40LG P29965 CD40 ligand chrX GO:0002684 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0002684 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0002684 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD5 CD5 P06127 T-cell surface glycoprotein CD5 chr11 GO:0002684 Not Cancer Driver No 67 0.135 146 19 0.13 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0002684 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0002684 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0002684 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0002684 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0002684 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0002684 Not Cancer Driver No 82 0.238 52 11 0.212 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0002684 Not Cancer Driver No 90 0.274 56 18 0.321 0
CD99 CD99 P14209 CD99 antigen chrX GO:0002684 Not Cancer Driver No 22 0.119 143 19 0.133 0
CD99L2_ENST00000370377 CD99L2 Q8TCZ2 CD99 antigen-like protein 2 chrX GO:0002684 Not Cancer Driver No 57 0.218 193 47 0.244 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0002684 Census, Compendium Yes 48 0.293 121 30 0.248 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0002684 Census, Compendium Yes 12 0.034 342 12 0.035 1
CFB CFB P00751 Complement factor B chr6 GO:0002684 Not Cancer Driver No 75 0.098 112 20 0.179 7
CFD_ENST00000327726 CFD P00746 Complement factor D chr19 GO:0002684 Not Cancer Driver No 6 0.024 69 3 0.043 2
CFH CFH P08603 Complement factor H chr1 GO:0002684 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFHR5 CFHR5 Q9BXR6 Complement factor H-related protein 5 chr1 GO:0002684 Not Cancer Driver No 162 0.285 40 9 0.225 0
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 GO:0002684 Not Cancer Driver No 97 0.166 4 0 0.0 13
CFP CFP P27918 Properdin chrX GO:0002684 Not Cancer Driver No 60 0.128 48 7 0.146 6
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0002684 Not Cancer Driver No 92 0.183 23 2 0.087 2
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0002684 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0002684 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0002684 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0002684 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0002684 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0002684 Not Cancer Driver No 69 0.154 156 27 0.173 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0002684 Not Cancer Driver No 107 0.287 24 13 0.542 0
CMTM3_ENST00000567572 CMTM3 Q96MX0 CKLF-like MARVEL transmembrane domain-containing protein 3 chr16 GO:0002684 Not Cancer Driver No 16 0.088 39 1 0.026 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0002684 Not Cancer Driver No 129 0.273 9 1 0.111 0
COLEC10 COLEC10 Q9Y6Z7 Collectin-10 chr8 GO:0002684 Not Cancer Driver No 58 0.209 95 23 0.242 1
COLEC11_ENST00000349077 COLEC11 Q9BWP8 Collectin-11 chr2 GO:0002684 Not Cancer Driver No 72 0.266 158 40 0.253 2
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0002684 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0002684 Not Cancer Driver No 273 0.264 85 28 0.329 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0002684 Census Yes 25 0.076 277 23 0.083 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0002684 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0002684 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX GO:0002684 Census Yes 54 0.146 62 3 0.048 0
CRP CRP P02741 C-reactive protein chr1 GO:0002684 Not Cancer Driver No 59 0.263 0 0 0.0 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0002684 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0002684 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0002684 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0002684 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0002684 Not Cancer Driver No 8 0.099 64 7 0.109 0
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:0002684 Not Cancer Driver No 64 0.138 19 5 0.263 29
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0002684 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0002684 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0002684 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0002684 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0002684 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL17 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0002684 Not Cancer Driver No 8 0.067 44 6 0.136 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0002684 Not Cancer Driver No 17 0.172 0 0 0.0 0
DAPK2 DAPK2 Q9UIK4 Death-associated protein kinase 2 chr15 GO:0002684 Not Cancer Driver No 55 0.149 53 9 0.17 0
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0002684 Compendium Yes 150 0.319 6 3 0.5 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0002684 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0002684 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0002684 Not Cancer Driver No 118 0.128 61 10 0.164 2
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0002684 Not Cancer Driver No 224 0.131 131 12 0.092 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0002684 Not Cancer Driver No 9 0.127 3 0 0.0 0
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0002684 Not Cancer Driver No 69 0.089 299 19 0.064 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0002684 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0002684 Not Cancer Driver No 62 0.091 84 8 0.095 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0002684 Not Cancer Driver No 67 0.091 212 23 0.108 7
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0002684 Not Cancer Driver No 321 0.153 312 60 0.192 1
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0002684 Not Cancer Driver No 151 0.197 8 1 0.125 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0002684 Not Cancer Driver No 81 0.168 135 24 0.178 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0002684 Not Cancer Driver No 32 0.14 10 1 0.1 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0002684 Not Cancer Driver No 37 0.175 97 20 0.206 3
EFNB1 EFNB1 P98172 Ephrin-B1 chrX GO:0002684 Not Cancer Driver No 46 0.133 126 14 0.111 19
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0002684 Not Cancer Driver No 42 0.126 97 15 0.155 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0002684 Not Cancer Driver No 45 0.132 183 22 0.12 0
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0002684 Not Cancer Driver No 60 0.155 252 46 0.183 0
ENPP3_ENST00000357639 ENPP3 O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 chr6 GO:0002684 Not Cancer Driver No 146 0.167 57 12 0.211 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0002684 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0002684 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPO EPO P01588 Erythropoietin chr7 GO:0002684 Not Cancer Driver No 27 0.14 9 1 0.111 1
EVI2B_ENST00000577894 EVI2B P34910 Protein EVI2B chr17 GO:0002684 Not Cancer Driver No 63 0.141 373 55 0.147 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0002684 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0002684 Not Cancer Driver No 3 0.011 102 0 0.0 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0002684 Not Cancer Driver No 55 0.139 7 2 0.286 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0002684 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM19A3_ENST00000361886 TAFA3 Q7Z5A8 Chemokine-like protein TAFA-3 chr1 GO:0002684 Not Cancer Driver No 17 0.128 6 0 0.0 0
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0002684 Not Cancer Driver No 53 0.164 78 11 0.141 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 GO:0002684 Not Cancer Driver No 133 0.112 440 48 0.109 1
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0002684 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0002684 Not Cancer Driver No 41 0.128 130 22 0.169 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0002684 Census Yes 51 0.165 99 30 0.303 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 GO:0002684 Not Cancer Driver No 69 0.272 0 0 0.0 1
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0002684 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:0002684 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0002684 Not Cancer Driver No 46 0.154 65 19 0.292 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0002684 Not Cancer Driver No 193 0.263 217 44 0.203 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0002684 Not Cancer Driver No 114 0.139 145 21 0.145 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0002684 Census Yes 103 0.125 245 34 0.139 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0002684 Not Cancer Driver No 49 0.148 32 7 0.219 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0002684 Not Cancer Driver No 78 0.225 29 6 0.207 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0002684 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0002684 Not Cancer Driver No 85 0.161 52 8 0.154 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 GO:0002684 Not Cancer Driver No 56 0.131 20 3 0.15 0
FOS FOS P01100 Protein c-Fos chr14 GO:0002684 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0002684 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0002684 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0002684 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0002684 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0002684 Not Cancer Driver No 38 0.088 186 16 0.086 10
FPR1_ENST00000304748 FPR1 P21462 fMet-Leu-Phe receptor chr19 GO:0002684 Not Cancer Driver No 99 0.283 18 3 0.167 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0002684 Not Cancer Driver No 96 0.274 26 5 0.192 0
FPR3 FPR3 P25089 N-formyl peptide receptor 3 chr19 GO:0002684 Not Cancer Driver No 82 0.232 28 2 0.071 0
FUT4 FUT4 P22083 Alpha-(1,3)-fucosyltransferase 4 chr11 GO:0002684 Not Cancer Driver No 49 0.092 193 9 0.047 0
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0002684 Not Cancer Driver No 28 0.082 25 3 0.12 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0002684 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0002684 Not Cancer Driver No 45 0.077 58 4 0.069 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 GO:0002684 Not Cancer Driver No 85 0.126 537 73 0.136 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0002684 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0002684 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0002684 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0002684 Census, Compendium Yes 111 0.251 364 87 0.239 2
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0002684 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0002684 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0002684 Not Cancer Driver No 108 0.13 83 7 0.084 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0002684 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0002684 Not Cancer Driver No 53 0.147 25 3 0.12 0
GPR32 GPR32 O75388 Probable G-protein coupled receptor 32 chr19 GO:0002684 Not Cancer Driver No 85 0.239 18 6 0.333 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0002684 Not Cancer Driver No 42 0.115 45 1 0.022 1
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0002684 Not Cancer Driver No 82 0.203 75 19 0.253 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0002684 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAVCR1_ENST00000339252 HAVCR1 Q96D42 Hepatitis A virus cellular receptor 1 chr5 GO:0002684 Not Cancer Driver No 95 0.261 156 48 0.308 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0002684 Not Cancer Driver No 69 0.229 17 2 0.118 3
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0002684 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0002684 Not Cancer Driver No 78 0.215 43 8 0.186 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0002684 Not Cancer Driver No 112 0.213 124 25 0.202 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0002684 Not Cancer Driver No 103 0.212 446 94 0.211 0
HHLA2_ENST00000489514 HHLA2 Q9UM44 HERV-H LTR-associating protein 2 chr3 GO:0002684 Not Cancer Driver No 85 0.205 57 10 0.175 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0002684 Not Cancer Driver No 127 0.138 75 16 0.213 6
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0002684 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0002684 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DMB HLA-DMB P28068 HLA class II histocompatibility antigen, DM beta chain chr6 GO:0002684 Not Cancer Driver No 41 0.156 41 9 0.22 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0002684 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0002684 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0002684 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0002684 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0002684 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0002684 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0002684 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0002684 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0002684 Not Cancer Driver No 46 0.16 81 13 0.16 0
HPX HPX P02790 Hemopexin chr11 GO:0002684 Not Cancer Driver No 60 0.13 53 8 0.151 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0002684 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0002684 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0002684 Not Cancer Driver No 61 0.106 82 6 0.073 2
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 GO:0002684 Not Cancer Driver No 103 0.12 323 42 0.13 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0002684 Not Cancer Driver No 61 0.115 251 28 0.112 0
ICOS ICOS Q9Y6W8 Inducible T-cell costimulator chr2 GO:0002684 Not Cancer Driver No 36 0.181 0 0 0.0 0
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0002684 Not Cancer Driver No 25 0.083 30 2 0.067 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0002684 Not Cancer Driver No 14 0.104 52 7 0.135 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0002684 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0002684 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0002684 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0002684 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0002684 Not Cancer Driver No 32 0.098 171 24 0.14 0
IGHD IGHD P01880 Immunoglobulin heavy constant delta chr14 GO:0002684 Not Cancer Driver No 61 0.159 245 40 0.163 0
IGLL1 IGLL1 P15814 Immunoglobulin lambda-like polypeptide 1 chr22 GO:0002684 Not Cancer Driver No 25 0.117 144 18 0.125 1
IGLL5 IGLL5 B9A064 Immunoglobulin lambda-like polypeptide 5 chr22 GO:0002684 Not Cancer Driver No 59 0.276 127 35 0.276 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0002684 Not Cancer Driver No 58 0.141 111 15 0.135 6
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0002684 Census, Compendium Yes 106 0.14 211 31 0.147 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0002684 Not Cancer Driver No 108 0.151 76 13 0.171 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0002684 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL10 IL10 P22301 Interleukin-10 chr1 GO:0002684 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0002684 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0002684 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0002684 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX GO:0002684 Not Cancer Driver No 69 0.182 0 0 0.0 0
IL15RA_ENST00000379977 IL15RA Q13261 Interleukin-15 receptor subunit alpha chr10 GO:0002684 Not Cancer Driver No 40 0.15 173 32 0.185 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0002684 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0002684 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0002684 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0002684 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0002684 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0002684 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0002684 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0002684 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL1RL1 IL1RL1 Q01638 Interleukin-1 receptor-like 1 chr2 GO:0002684 Not Cancer Driver No 119 0.214 24 8 0.333 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0002684 Census Yes 24 0.157 6 1 0.167 0
IL20_ENST00000367096 IL20 Q9NYY1 Interleukin-20 chr1 GO:0002684 Not Cancer Driver No 30 0.17 0 0 0.0 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0002684 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0002684 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0002684 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0002684 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0002684 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL33 IL33 O95760 Interleukin-33 chr9 GO:0002684 Not Cancer Driver No 47 0.174 47 8 0.17 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0002684 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0002684 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0002684 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0002684 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0002684 Not Cancer Driver No 13 0.097 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0002684 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL7 IL7 P13232 Interleukin-7 chr8 GO:0002684 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0002684 Census, Compendium Yes 177 0.386 88 48 0.545 1
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 GO:0002684 Not Cancer Driver No 112 0.169 553 98 0.177 1
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0002684 Not Cancer Driver No 176 0.148 578 90 0.156 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0002684 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0002684 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0002684 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0002684 Not Cancer Driver No 9 0.05 45 1 0.022 0
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0002684 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0002684 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0002684 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0002684 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0002684 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0002684 Not Cancer Driver No 148 0.156 719 119 0.166 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0002684 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0002684 Census, Compendium Yes 167 0.149 63 10 0.159 7
JAM2_ENST00000480456 JAM2 P57087 Junctional adhesion molecule B chr21 GO:0002684 Not Cancer Driver No 63 0.211 64 16 0.25 2
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0002684 Not Cancer Driver No 50 0.161 62 11 0.177 2
JUND JUND P17535 Transcription factor JunD chr19 GO:0002684 Not Cancer Driver No 21 0.061 313 19 0.061 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0002684 Not Cancer Driver No 88 0.147 160 15 0.094 12
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0002684 Not Cancer Driver No 60 0.141 31 6 0.194 3
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0002684 Census, Compendium Yes 226 0.232 83 33 0.398 21
KITLG KITLG P21583 Kit ligand chr12 GO:0002684 Not Cancer Driver No 48 0.176 61 9 0.148 1
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 GO:0002684 Not Cancer Driver No 59 0.123 349 46 0.132 0
KLK3 KLK3 P07288 Prostate-specific antigen chr19 GO:0002684 Not Cancer Driver No 68 0.261 6 1 0.167 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 GO:0002684 Not Cancer Driver No 69 0.235 75 16 0.213 0
KLK7 KLK7 P49862 Kallikrein-7 chr19 GO:0002684 Not Cancer Driver No 43 0.17 38 8 0.211 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0002684 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRC3_ENST00000396439 KLRC3 Q07444 NKG2-E type II integral membrane protein chr12 GO:0002684 Not Cancer Driver No 37 0.154 43 4 0.093 0
KLRC4 KLRC4 O43908 NKG2-F type II integral membrane protein chr12 GO:0002684 Not Cancer Driver No 36 0.228 45 7 0.156 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0002684 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0002684 Not Cancer Driver No 38 0.176 0 0 0.0 0
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0002684 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0002684 Not Cancer Driver No 37 0.08 142 9 0.063 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0002684 Not Cancer Driver No 133 0.207 426 98 0.23 20
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 GO:0002684 Not Cancer Driver No 50 0.116 4 0 0.0 1
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0002684 Not Cancer Driver No 47 0.113 93 10 0.108 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0002684 Not Cancer Driver No 46 0.176 16 6 0.375 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0002684 Not Cancer Driver No 84 0.175 6 0 0.0 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0002684 Census Yes 86 0.169 94 13 0.138 1
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0002684 Census Yes 64 0.16 370 57 0.154 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0002684 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0002684 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0002684 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0002684 Not Cancer Driver No 57 0.132 112 19 0.17 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0002684 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0002684 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0002684 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0002684 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0002684 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0002684 Not Cancer Driver No 110 0.17 170 30 0.176 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0002684 Not Cancer Driver No 519 0.205 90 17 0.189 23
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 GO:0002684 Census Yes 67 0.145 408 63 0.154 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0002684 Not Cancer Driver No 37 0.18 20 5 0.25 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0002684 Census Yes 95 0.186 84 12 0.143 0
LYVE1 LYVE1 Q9Y5Y7 Lymphatic vessel endothelial hyaluronic acid receptor 1 chr11 GO:0002684 Not Cancer Driver No 34 0.106 77 13 0.169 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0002684 Not Cancer Driver No 22 0.104 0 0 0.0 1
MADCAM1 MADCAM1 Q13477 Mucosal addressin cell adhesion molecule 1 chr19 GO:0002684 Not Cancer Driver No 39 0.102 240 33 0.138 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0002684 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0002684 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP3K8_ENST00000542547 MAP3K8 P41279 Mitogen-activated protein kinase kinase kinase 8 chr10 GO:0002684 Not Cancer Driver No 58 0.124 109 10 0.092 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0002684 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0002684 Not Cancer Driver No 38 0.1 49 5 0.102 0
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 GO:0002684 Not Cancer Driver No 142 0.203 72 14 0.194 0
MASP2 MASP2 O00187 Mannan-binding lectin serine protease 2 chr1 GO:0002684 Not Cancer Driver No 99 0.144 58 11 0.19 2
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0002684 Not Cancer Driver No 70 0.13 411 58 0.141 0
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0002684 Not Cancer Driver No 63 0.254 122 32 0.262 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0002684 Not Cancer Driver No 41 0.117 13 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0002684 Not Cancer Driver No 15 0.105 20 2 0.1 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0002684 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0002684 Not Cancer Driver No 92 0.195 408 81 0.199 0
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0002684 Not Cancer Driver No 35 0.137 0 0 0.0 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0002684 Not Cancer Driver No 4 0.035 0 0 0.0 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0002684 Census Yes 92 0.122 208 22 0.106 85
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0002684 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0002684 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0002684 Not Cancer Driver No 73 0.156 115 19 0.165 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX GO:0002684 Not Cancer Driver No 58 0.112 143 16 0.112 0
MPL MPL P40238 Thrombopoietin receptor chr1 GO:0002684 Census Yes 77 0.121 129 19 0.147 14
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0002684 Not Cancer Driver No 60 0.176 33 7 0.212 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0002684 Census Yes 92 0.099 37 4 0.108 70
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0002684 Not Cancer Driver No 68 0.181 64 11 0.172 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0002684 Census Yes 82 0.128 528 69 0.131 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0002684 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 GO:0002684 Not Cancer Driver No 268 0.13 1237 176 0.142 0
MYO1G MYO1G B0I1T2 Unconventional myosin-Ig chr7 GO:0002684 Not Cancer Driver No 125 0.123 117 12 0.103 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0002684 Not Cancer Driver No 247 0.219 51 10 0.196 4
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0002684 Not Cancer Driver No 63 0.117 296 29 0.098 0
NFAM1 NFAM1 Q8NET5 NFAT activation molecule 1 chr22 GO:0002684 Not Cancer Driver No 30 0.111 116 18 0.155 0
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 GO:0002684 Census, Compendium Yes 194 0.21 722 162 0.224 0
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0002684 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0002684 Not Cancer Driver No 96 0.134 443 53 0.12 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0002684 Not Cancer Driver No 80 0.193 409 77 0.188 3
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0002684 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP10 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 GO:0002684 Not Cancer Driver No 201 0.307 96 34 0.354 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0002684 Not Cancer Driver No 339 0.327 64 33 0.516 37
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0002684 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0002684 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0002684 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0002684 Census, Compendium Yes 282 0.114 630 77 0.122 1
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0002684 Census Yes 83 0.133 298 37 0.124 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0002684 Census, Compendium Yes 191 0.14 552 76 0.138 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0002684 Not Cancer Driver No 22 0.039 52 6 0.115 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0002684 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0002684 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0002684 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0002684 Not Cancer Driver No 57 0.167 21 2 0.095 3
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0002684 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0002684 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0002684 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0002684 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0002684 Not Cancer Driver No 110 0.129 45 3 0.067 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0002684 Not Cancer Driver No 120 0.112 461 39 0.085 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0002684 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0002684 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0002684 Census, Compendium Yes 33 0.121 41 13 0.317 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0002684 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0002684 Not Cancer Driver No 33 0.059 121 12 0.099 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0002684 Not Cancer Driver No 47 0.112 167 17 0.102 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0002684 Not Cancer Driver No 13 0.129 0 0 0.0 0
PGC PGC P20142 Gastricsin chr6 GO:0002684 Not Cancer Driver No 60 0.155 20 1 0.05 0
PGF_ENST00000405431 PGF P49763 Placenta growth factor chr14 GO:0002684 Not Cancer Driver No 30 0.136 72 10 0.139 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0002684 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0002684 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0002684 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0002684 Not Cancer Driver No 140 0.134 60 13 0.217 1
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0002684 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0002684 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0002684 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0002684 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0002684 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0002684 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 GO:0002684 Not Cancer Driver No 107 0.115 97 8 0.082 0
PLPP4 PLPP4 Q5VZY2 Phospholipid phosphatase 4 chr10 GO:0002684 Not Cancer Driver No 59 0.218 14 1 0.071 0
PLPP6 PLPP6 Q8IY26 Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 chr9 GO:0002684 Not Cancer Driver No 16 0.054 80 0 0.0 0
PLVAP PLVAP Q9BX97 Plasmalemma vesicle-associated protein chr19 GO:0002684 Not Cancer Driver No 96 0.217 174 39 0.224 1
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0002684 Not Cancer Driver No 38 0.131 29 2 0.069 5
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0002684 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0002684 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0002684 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0002684 Not Cancer Driver No 44 0.097 30 3 0.1 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0002684 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0002684 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0002684 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0002684 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0002684 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0002684 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0002684 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0002684 Compendium Yes 118 0.134 246 34 0.138 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0002684 Not Cancer Driver No 538 0.13 421 61 0.145 2
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0002684 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0002684 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0002684 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0002684 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0002684 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0002684 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0002684 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0002684 Not Cancer Driver No 184 0.138 401 61 0.152 0
PVR PVR P15151 Poliovirus receptor chr19 GO:0002684 Not Cancer Driver No 39 0.094 120 19 0.158 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0002684 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0002684 Not Cancer Driver No 28 0.138 18 3 0.167 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0002684 Not Cancer Driver No 73 0.149 175 35 0.2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0002684 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0002684 Not Cancer Driver No 31 0.161 0 0 0.0 2
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0002684 Not Cancer Driver No 41 0.123 62 10 0.161 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0002684 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0002684 Not Cancer Driver No 16 0.098 14 2 0.143 0
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 GO:0002684 Not Cancer Driver No 114 0.113 536 68 0.127 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0002684 Not Cancer Driver No 96 0.12 191 12 0.063 1
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0002684 Census, Compendium Yes 140 0.151 282 32 0.113 22
RELA RELA Q04206 Transcription factor p65 chr11 GO:0002684 Compendium Yes 75 0.136 400 48 0.12 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0002684 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0002684 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0002684 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0002684 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0002684 Not Cancer Driver No 131 0.123 421 76 0.181 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0002684 Not Cancer Driver No 25 0.13 82 15 0.183 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0002684 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0002684 Not Cancer Driver No 15 0.103 61 3 0.049 23
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0002684 Not Cancer Driver No 22 0.091 48 4 0.083 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0002684 Not Cancer Driver No 68 0.188 22 1 0.045 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0002684 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0002684 Not Cancer Driver No 59 0.142 331 45 0.136 0
S100A14_ENST00000368701 S100A14 Q9HCY8 Protein S100-A14 chr1 GO:0002684 Not Cancer Driver No 15 0.144 55 9 0.164 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0002684 Census Yes 39 0.386 28 14 0.5 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:0002684 Not Cancer Driver No 71 0.089 685 63 0.092 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0002684 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0002684 Not Cancer Driver No 10 0.069 73 9 0.123 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0002684 Not Cancer Driver No 10 0.106 47 6 0.128 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0002684 Not Cancer Driver No 81 0.122 150 21 0.14 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0002684 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 GO:0002684 Not Cancer Driver No 74 0.148 113 13 0.115 40
SH2D1B SH2D1B O14796 SH2 domain-containing protein 1B chr1 GO:0002684 Not Cancer Driver No 34 0.258 0 0 0.0 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX GO:0002684 Not Cancer Driver No 102 0.153 530 82 0.155 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0002684 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0002684 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0002684 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0002684 Not Cancer Driver No 3 0.012 81 1 0.012 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0002684 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0002684 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0002684 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC22A13 SLC22A13 Q9Y226 Solute carrier family 22 member 13 chr3 GO:0002684 Not Cancer Driver No 55 0.1 32 3 0.094 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0002684 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 GO:0002684 Not Cancer Driver No 62 0.122 35 1 0.029 0
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:0002684 Not Cancer Driver No 68 0.127 80 16 0.2 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0002684 Not Cancer Driver No 31 0.069 101 5 0.05 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0002684 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0002684 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOX12 SOX12 O15370 Transcription factor SOX-12 chr20 GO:0002684 Not Cancer Driver No 20 0.063 307 19 0.062 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0002684 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0002684 Not Cancer Driver No 28 0.059 400 24 0.06 4
SPACA3 SPACA3 Q8IXA5 Sperm acrosome membrane-associated protein 3 chr17 GO:0002684 Not Cancer Driver No 52 0.242 0 0 0.0 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0002684 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0002684 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0002684 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 GO:0002684 Not Cancer Driver No 36 0.109 73 4 0.055 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0002684 Census Yes 53 0.099 130 11 0.085 1
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0002684 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0002684 Census, Compendium Yes 93 0.118 144 19 0.132 5
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0002684 Census, Compendium Yes 106 0.125 325 44 0.135 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0002684 Not Cancer Driver No 64 0.117 182 19 0.104 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0002684 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX7 STX7 O15400 Syntaxin-7 chr6 GO:0002684 Not Cancer Driver No 29 0.111 164 14 0.085 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0002684 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0002684 Not Cancer Driver No 77 0.13 80 13 0.163 5
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 GO:0002684 Not Cancer Driver No 85 0.173 134 27 0.201 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0002684 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0002684 Census Yes 96 0.151 131 27 0.206 5
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0002684 Not Cancer Driver No 69 0.17 28 2 0.071 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0002684 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0002684 Not Cancer Driver No 70 0.131 348 50 0.144 0
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0002684 Not Cancer Driver No 31 0.145 73 6 0.082 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0002684 Not Cancer Driver No 127 0.244 284 84 0.296 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0002684 Census Yes 89 0.117 80 6 0.075 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0002684 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0002684 Census, Compendium Yes 106 0.187 60 16 0.267 25
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0002684 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 GO:0002684 Not Cancer Driver No 137 0.143 281 40 0.142 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0002684 Not Cancer Driver No 24 0.149 5 0 0.0 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0002684 Not Cancer Driver No 92 0.129 443 66 0.149 1
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0002684 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0002684 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0002684 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0002684 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM102 TMEM102 Q8N9M5 Transmembrane protein 102 chr17 GO:0002684 Not Cancer Driver No 38 0.075 141 13 0.092 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0002684 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM64 TMEM64 Q6YI46 Transmembrane protein 64 chr8 GO:0002684 Not Cancer Driver No 33 0.087 32 0 0.0 0
TMIGD2 TMIGD2 Q96BF3 Transmembrane and immunoglobulin domain-containing protein 2 chr19 GO:0002684 Not Cancer Driver No 57 0.202 120 32 0.267 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0002684 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF13C TNFRSF13C Q96RJ3 Tumor necrosis factor receptor superfamily member 13C chr22 GO:0002684 Not Cancer Driver No 17 0.092 128 15 0.117 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0002684 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF4 TNFRSF4 P43489 Tumor necrosis factor receptor superfamily member 4 chr1 GO:0002684 Not Cancer Driver No 30 0.108 94 14 0.149 1
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0002684 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0002684 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 GO:0002684 Not Cancer Driver No 41 0.144 91 15 0.165 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0002684 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0002684 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:0002684 Not Cancer Driver No 32 0.126 39 4 0.103 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 GO:0002684 Not Cancer Driver No 43 0.1 316 36 0.114 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0002684 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0002684 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0002684 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0002684 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0002684 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0002684 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0002684 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0002684 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0002684 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM62 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 GO:0002684 Not Cancer Driver No 58 0.122 80 14 0.175 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0002684 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0002684 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 GO:0002684 Not Cancer Driver No 27 0.17 16 0 0.0 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0002684 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0002684 Not Cancer Driver No 87 0.165 61 9 0.148 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0002684 Not Cancer Driver No 148 0.125 213 29 0.136 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0002684 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0002684 Not Cancer Driver No 24 0.12 33 3 0.091 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0002684 Not Cancer Driver No 120 0.11 248 30 0.121 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0002684 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP27X USP27X A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 chrX GO:0002684 Not Cancer Driver No 31 0.071 69 3 0.043 1
USP29_ENST00000598197 USP29 Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 chr19 GO:0002684 Not Cancer Driver No 291 0.316 432 132 0.306 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0002684 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0002684 Not Cancer Driver No 9 0.09 27 0 0.0 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0002684 Census, Compendium Yes 165 0.195 113 19 0.168 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0002684 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0002684 Not Cancer Driver No 153 0.181 102 18 0.176 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0002684 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFB VEGFB P49765 Vascular endothelial growth factor B chr11 GO:0002684 Not Cancer Driver No 25 0.121 125 22 0.176 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0002684 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0002684 Not Cancer Driver No 59 0.167 33 6 0.182 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0002684 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0002684 Not Cancer Driver No 73 0.183 70 13 0.186 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0002684 Not Cancer Driver No 52 0.167 135 19 0.141 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0002684 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0002684 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0002684 Not Cancer Driver No 66 0.174 0 0 0.0 2
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0002684 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0002684 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0002684 Not Cancer Driver No 20 0.175 35 5 0.143 0
XG_ENST00000381174 XG P55808 Glycoprotein Xg chrX GO:0002684 Not Cancer Driver No 27 0.15 140 23 0.164 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0002684 Not Cancer Driver No 66 0.108 140 12 0.086 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0002684 Not Cancer Driver No 65 0.12 62 10 0.161 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0002684 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0002684 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0002684 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0002684 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZBTB46_ENST00000302995 ZBTB46 Q86UZ6 Zinc finger and BTB domain-containing protein 46 chr20 GO:0002684 Not Cancer Driver No 115 0.195 301 68 0.226 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0002684 Compendium Yes 103 0.191 353 70 0.198 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0002684 Compendium Yes 57 0.169 212 30 0.142 0
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0002684 Not Cancer Driver No 185 0.138 942 133 0.141 1
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0002684 Not Cancer Driver No 55 0.13 56 11 0.196 1
ZP4 ZP4 Q12836 Zona pellucida sperm-binding protein 4 chr1 GO:0002684 Not Cancer Driver No 189 0.35 46 15 0.326 0