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Total number of protein in "GO:0002521" GO term:  197

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0002521 Census, Compendium Yes 139 0.123 604 73 0.121 2
ADA ADA P00813 Adenosine deaminase chr20 GO:0002521 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0002521 Not Cancer Driver No 80 0.097 182 17 0.093 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0002521 Not Cancer Driver No 126 0.115 316 31 0.098 1
ARMC5_ENST00000563544 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 GO:0002521 Not Cancer Driver No 135 0.144 267 41 0.154 17
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0002521 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0002521 Not Cancer Driver No 228 0.152 171 46 0.269 52
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0002521 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZI2 AZI2 Q9H6S1 5-azacytidine-induced protein 2 chr3 GO:0002521 Not Cancer Driver No 31 0.079 192 13 0.068 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0002521 Census, Compendium Yes 34 0.286 5 1 0.2 2
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0002521 Not Cancer Driver No 28 0.224 119 25 0.21 0
BATF2 BATF2 Q8N1L9 Basic leucine zipper transcriptional factor ATF-like 2 chr11 GO:0002521 Not Cancer Driver No 28 0.102 202 19 0.094 0
BATF3 BATF3 Q9NR55 Basic leucine zipper transcriptional factor ATF-like 3 chr1 GO:0002521 Not Cancer Driver No 18 0.142 127 18 0.142 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0002521 Census, Compendium Yes 156 0.174 699 114 0.163 2
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0002521 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0002521 Census Yes 44 0.097 259 23 0.089 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0002521 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0002521 Not Cancer Driver No 86 0.211 142 26 0.183 5
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0002521 Not Cancer Driver No 16 0.06 84 3 0.036 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0002521 Not Cancer Driver No 101 0.214 127 30 0.236 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0002521 Census, Compendium Yes 142 0.296 106 12 0.113 1
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 GO:0002521 Census, Compendium Yes 83 0.127 502 70 0.139 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0002521 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0002521 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0002521 Census, Compendium Yes 50 0.132 0 0 0.0 0
CCR9 CCR9 P51686 C-C chemokine receptor type 9 chr3 GO:0002521 Not Cancer Driver No 60 0.163 0 0 0.0 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0002521 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0002521 Census Yes 42 0.191 18 10 0.556 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0002521 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD8A_ENST00000283635 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 GO:0002521 Not Cancer Driver No 33 0.14 28 2 0.071 1
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0002521 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH17 CDH17 Q12864 Cadherin-17 chr8 GO:0002521 Census Yes 166 0.2 186 35 0.188 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0002521 Census Yes 40 0.123 24 3 0.125 1
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0002521 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPE CEBPE Q15744 CCAAT/enhancer-binding protein epsilon chr14 GO:0002521 Not Cancer Driver No 56 0.199 257 53 0.206 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0002521 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0002521 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 GO:0002521 Not Cancer Driver No 56 0.256 5 2 0.4 0
CMTM7 CMTM7 Q96FZ5 CKLF-like MARVEL transmembrane domain-containing protein 7 chr3 GO:0002521 Not Cancer Driver No 25 0.143 0 0 0.0 0
CRACR2A CRACR2A Q9BSW2 EF-hand calcium-binding domain-containing protein 4B chr12 GO:0002521 Not Cancer Driver No 88 0.12 436 60 0.138 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0002521 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0002521 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0002521 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0002521 Not Cancer Driver No 20 0.097 7 0 0.0 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0002521 Census, Compendium Yes 415 0.531 288 301 1.045 14
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0002521 Compendium Yes 150 0.319 6 3 0.5 0
DHRS2_ENST00000250383 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 GO:0002521 Not Cancer Driver No 47 0.168 0 0 0.0 0
DHRS7B DHRS7B Q6IAN0 Dehydrogenase/reductase SDR family member 7B chr17 GO:0002521 Not Cancer Driver No 37 0.114 17 0 0.0 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0002521 Not Cancer Driver No 115 0.159 145 24 0.166 1
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 GO:0002521 Not Cancer Driver No 50 0.104 152 21 0.138 0
DOCK10 DOCK10 Q96BY6 Dedicator of cytokinesis protein 10 chr2 GO:0002521 Not Cancer Driver No 368 0.168 409 58 0.142 0
DOCK11 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX GO:0002521 Not Cancer Driver No 312 0.151 240 29 0.121 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0002521 Not Cancer Driver No 87 0.138 238 29 0.122 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0002521 Not Cancer Driver No 90 0.149 26 3 0.115 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0002521 Not Cancer Driver No 82 0.12 436 50 0.115 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0002521 Not Cancer Driver No 55 0.139 7 2 0.286 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0002521 Not Cancer Driver No 26 0.125 45 10 0.222 1
FASN FASN P49327 Fatty acid synthase chr17 GO:0002521 Not Cancer Driver No 291 0.116 309 42 0.136 0
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0002521 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0002521 Census Yes 51 0.165 99 30 0.303 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0002521 Census, Compendium Yes 200 0.201 64 27 0.422 0
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0002521 Not Cancer Driver No 143 0.123 384 44 0.115 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0002521 Census, Compendium Yes 109 0.161 448 71 0.158 3
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0002521 Not Cancer Driver No 28 0.082 25 3 0.12 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0002521 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0002521 Not Cancer Driver No 90 0.157 22 2 0.091 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0002521 Not Cancer Driver No 72 0.104 146 3 0.021 0
GAB3_ENST00000369575 GAB3 Q8WWW8 GRB2-associated-binding protein 3 chrX GO:0002521 Not Cancer Driver No 86 0.147 390 60 0.154 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0002521 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0002521 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0002521 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0002521 Not Cancer Driver No 74 0.138 38 5 0.132 171
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0002521 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0002521 Not Cancer Driver No 53 0.147 25 3 0.12 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0002521 Not Cancer Driver No 36 0.109 0 0 0.0 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 GO:0002521 Not Cancer Driver No 274 0.105 991 108 0.109 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0002521 Not Cancer Driver No 48 0.18 12 1 0.083 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0002521 Not Cancer Driver No 25 0.116 203 20 0.099 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0002521 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0002521 Not Cancer Driver No 51 0.307 23 6 0.261 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0002521 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0002521 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0002521 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0002521 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL25 IL25 Q9H293 Interleukin-25 chr14 GO:0002521 Not Cancer Driver No 30 0.169 50 8 0.16 0
IL31RA_ENST00000297015 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0002521 Not Cancer Driver No 117 0.16 163 30 0.184 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0002521 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0002521 Not Cancer Driver No 35 0.165 58 7 0.121 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0002521 Compendium Yes 49 0.151 228 31 0.136 2
IRF2BP2 IRF2BP2 Q7Z5L9 Interferon regulatory factor 2-binding protein 2 chr1 GO:0002521 Not Cancer Driver No 42 0.072 451 26 0.058 1
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0002521 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0002521 Not Cancer Driver No 80 0.188 77 20 0.26 2
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:0002521 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0002521 Not Cancer Driver No 120 0.152 26 4 0.154 3
ITGB8 ITGB8 P26012 Integrin beta-8 chr7 GO:0002521 Not Cancer Driver No 126 0.164 26 3 0.115 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0002521 Census Yes 139 0.224 43 10 0.233 1
ITM2A ITM2A O43736 Integral membrane protein 2A chrX GO:0002521 Not Cancer Driver No 75 0.285 26 9 0.346 0
JAG2 JAG2 Q9Y219 Protein jagged-2 chr14 GO:0002521 Not Cancer Driver No 126 0.102 158 24 0.152 0
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 GO:0002521 Not Cancer Driver No 21 0.115 12 2 0.167 5
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0002521 Not Cancer Driver No 51 0.127 133 21 0.158 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0002521 Census Yes 35 0.106 281 25 0.089 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0002521 Census Yes 97 0.159 327 47 0.144 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0002521 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0002521 Not Cancer Driver No 49 0.21 49 10 0.204 0
L3MBTL3_ENST00000368136 L3MBTL3 Q96JM7 Lethal(3)malignant brain tumor-like protein 3 chr6 GO:0002521 Not Cancer Driver No 117 0.15 351 59 0.168 0
LBR_ENST00000272163 LBR Q14739 Delta(14)-sterol reductase LBR chr1 GO:0002521 Not Cancer Driver No 95 0.154 130 15 0.115 5
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0002521 Census Yes 64 0.16 370 57 0.154 0
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0002521 Not Cancer Driver No 37 0.098 65 1 0.015 1
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0002521 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0002521 Not Cancer Driver No 54 0.152 65 16 0.246 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0002521 Not Cancer Driver No 134 0.147 63 10 0.159 2
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0002521 Not Cancer Driver No 203 0.312 291 97 0.333 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0002521 Not Cancer Driver No 105 0.13 32 3 0.094 0
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 GO:0002521 Not Cancer Driver No 44 0.101 200 21 0.105 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0002521 Census Yes 95 0.186 84 12 0.143 0
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:0002521 Census Yes 35 0.108 301 34 0.113 10
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0002521 Census, Compendium Yes 75 0.091 139 12 0.086 1
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0002521 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0002521 Not Cancer Driver No 175 0.175 159 31 0.195 3
MFNG MFNG O00587 Beta-1,3-N-acetylglucosaminyltransferase manic fringe chr22 GO:0002521 Not Cancer Driver No 37 0.115 29 4 0.138 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0002521 Not Cancer Driver No 129 0.182 124 26 0.21 0
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0002521 Not Cancer Driver No 60 0.176 33 7 0.212 0
MT1G MT1G P13640 Metallothionein-1G chr16 GO:0002521 Not Cancer Driver No 9 0.145 0 0 0.0 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0002521 Census, Compendium Yes 310 0.158 1120 160 0.143 17
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 GO:0002521 Not Cancer Driver No 67 0.111 335 39 0.116 0
NFIL3 NFIL3 Q16649 Nuclear factor interleukin-3-regulated protein chr9 GO:0002521 Not Cancer Driver No 57 0.123 333 41 0.123 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0002521 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKX2-3 NKX2-3 Q8TAU0 Homeobox protein Nkx-2.3 chr10 GO:0002521 Not Cancer Driver No 31 0.085 212 27 0.127 0
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0002521 Census, Compendium Yes 282 0.114 630 77 0.122 1
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0002521 Not Cancer Driver No 22 0.039 52 6 0.115 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0002521 Not Cancer Driver No 119 0.117 320 34 0.106 0
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0002521 Census Yes 82 0.191 290 57 0.197 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0002521 Not Cancer Driver No 114 0.213 132 30 0.227 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0002521 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIR_ENST00000380420 PIR O00625 Pirin chrX GO:0002521 Not Cancer Driver No 29 0.1 185 16 0.086 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0002521 Not Cancer Driver No 27 0.186 0 0 0.0 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0002521 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0002521 Not Cancer Driver No 185 0.164 274 31 0.113 0
POU2AF1 POU2AF1 Q16633 POU domain class 2-associating factor 1 chr11 GO:0002521 Census Yes 59 0.23 181 45 0.249 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0002521 Census Yes 72 0.143 44 4 0.091 3
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0002521 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0002521 Not Cancer Driver No 10 0.036 199 6 0.03 0
PRTN3 PRTN3 P24158 Myeloblastin chr19 GO:0002521 Not Cancer Driver No 20 0.078 46 1 0.022 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0002521 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMB11 PSMB11 A5LHX3 Proteasome subunit beta type-11 chr14 GO:0002521 Not Cancer Driver No 62 0.207 71 11 0.155 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0002521 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0002521 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0002521 Census, Compendium Yes 315 0.241 462 107 0.232 0
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 GO:0002521 Not Cancer Driver No 37 0.157 1 0 0.0 1
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0002521 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0002521 Not Cancer Driver No 118 0.224 85 23 0.271 6
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0002521 Not Cancer Driver No 49 0.098 151 19 0.126 2
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0002521 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0002521 Not Cancer Driver No 128 0.107 703 81 0.115 0
RELB RELB Q01201 Transcription factor RelB chr19 GO:0002521 Not Cancer Driver No 65 0.112 348 39 0.112 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0002521 Not Cancer Driver No 66 0.127 295 39 0.132 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0002521 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0002521 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0002521 Not Cancer Driver No 38 0.153 150 25 0.167 0
RRAS RRAS P10301 Ras-related protein R-Ras chr19 GO:0002521 Not Cancer Driver No 25 0.115 71 6 0.085 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0002521 Not Cancer Driver No 68 0.188 22 1 0.045 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0002521 Census, Compendium Yes 81 0.179 360 58 0.161 2
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0002521 Not Cancer Driver No 123 0.162 122 26 0.213 4
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0002521 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0002521 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0002521 Not Cancer Driver No 82 0.245 64 10 0.156 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0002521 Not Cancer Driver No 85 0.137 564 77 0.137 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0002521 Not Cancer Driver No 66 0.085 587 37 0.063 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0002521 Not Cancer Driver No 46 0.17 187 34 0.182 0
SRP54 SRP54 P61011 Signal recognition particle 54 kDa protein chr14 GO:0002521 Not Cancer Driver No 53 0.105 115 13 0.113 7
ST3GAL1_ENST00000522652 ST3GAL1 Q11201 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 chr8 GO:0002521 Not Cancer Driver No 51 0.15 6 0 0.0 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0002521 Census, Compendium Yes 93 0.118 144 19 0.132 5
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0002521 Not Cancer Driver No 63 0.102 284 32 0.113 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0002521 Census Yes 54 0.163 305 53 0.174 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0002521 Not Cancer Driver No 127 0.244 284 84 0.296 0
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 GO:0002521 Census, Compendium Yes 191 0.095 1663 176 0.106 1
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0002521 Census, Compendium Yes 106 0.187 60 16 0.267 25
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 GO:0002521 Not Cancer Driver No 88 0.129 173 25 0.145 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 GO:0002521 Not Cancer Driver No 39 0.173 27 3 0.111 2
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0002521 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF8 TNFSF8 P32971 Tumor necrosis factor ligand superfamily member 8 chr9 GO:0002521 Not Cancer Driver No 34 0.145 30 2 0.067 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0002521 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0002521 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0002521 Not Cancer Driver No 59 0.103 410 39 0.095 2
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0002521 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0002521 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0002521 Not Cancer Driver No 286 0.19 266 44 0.165 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0002521 Census, Compendium Yes 135 0.116 732 78 0.107 11
TUSC2 TUSC2 O75896 Tumor suppressor candidate 2 chr3 GO:0002521 Not Cancer Driver No 10 0.091 31 3 0.097 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0002521 Not Cancer Driver No 119 0.134 197 17 0.086 0
UBD UBD O15205 Ubiquitin D chr6 GO:0002521 Not Cancer Driver No 31 0.188 8 1 0.125 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0002521 Not Cancer Driver No 27 0.116 41 7 0.171 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0002521 Not Cancer Driver No 29 0.078 25 0 0.0 8
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0002521 Compendium Yes 103 0.191 353 70 0.198 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0002521 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0002521 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZFPM1 ZFPM1 Q8IX07 Zinc finger protein ZFPM1 chr16 GO:0002521 Not Cancer Driver No 50 0.05 772 27 0.035 0