Total number of protein in "GO:0002443" GO term: 88
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0002443 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0002443 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| AIRE | AIRE | O43918 | Autoimmune regulator | chr21 | GO:0002443 | Not Cancer Driver | No | 71 | 0.13 | 338 | 48 | 0.142 | 19 |
| ARL8B | ARL8B | Q9NVJ2 | ADP-ribosylation factor-like protein 8B | chr3 | GO:0002443 | Not Cancer Driver | No | 28 | 0.151 | 0 | 0 | 0.0 | 0 |
| AZU1 | AZU1 | P20160 | Azurocidin | chr19 | GO:0002443 | Not Cancer Driver | No | 42 | 0.167 | 53 | 13 | 0.245 | 0 |
| BCL10 | BCL10 | O95999 | B-cell lymphoma/leukemia 10 | chr1 | GO:0002443 | Census, Compendium | Yes | 36 | 0.155 | 151 | 25 | 0.166 | 0 |
| BCL3 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | GO:0002443 | Census | Yes | 44 | 0.097 | 259 | 23 | 0.089 | 0 |
| CADM1_ENST00000452722 | CADM1 | Q9BY67 | Cell adhesion molecule 1 | chr11 | GO:0002443 | Not Cancer Driver | No | 106 | 0.24 | 103 | 28 | 0.272 | 0 |
| CARD9 | CARD9 | Q9H257 | Caspase recruitment domain-containing protein 9 | chr9 | GO:0002443 | Not Cancer Driver | No | 72 | 0.134 | 225 | 35 | 0.156 | 11 |
| CD19_ENST00000324662 | CD19 | P15391 | B-lymphocyte antigen CD19 | chr16 | GO:0002443 | Not Cancer Driver | No | 80 | 0.144 | 312 | 46 | 0.147 | 0 |
| CD27 | CD27 | P26842 | CD27 antigen | chr12 | GO:0002443 | Not Cancer Driver | No | 30 | 0.115 | 92 | 11 | 0.12 | 1 |
| CD40 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0002443 | Not Cancer Driver | No | 39 | 0.141 | 56 | 6 | 0.107 | 2 |
| CD70_ENST00000245903 | CD70 | P32970 | CD70 antigen | chr19 | GO:0002443 | Not Cancer Driver | No | 33 | 0.171 | 11 | 2 | 0.182 | 0 |
| CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0002443 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
| CD81 | CD81 | P60033 | CD81 antigen | chr11 | GO:0002443 | Not Cancer Driver | No | 28 | 0.119 | 0 | 0 | 0.0 | 0 |
| CEBPG_ENST00000585933 | CEBPG | P53567 | CCAAT/enhancer-binding protein gamma | chr19 | GO:0002443 | Not Cancer Driver | No | 13 | 0.087 | 141 | 12 | 0.085 | 0 |
| CLEC2A | CLEC2A | Q6UVW9 | C-type lectin domain family 2 member A | chr12 | GO:0002443 | Not Cancer Driver | No | 10 | 0.057 | 0 | 0 | 0.0 | 0 |
| CRTAM | CRTAM | O95727 | Cytotoxic and regulatory T-cell molecule | chr11 | GO:0002443 | Not Cancer Driver | No | 64 | 0.163 | 135 | 14 | 0.104 | 0 |
| CSF2RB | CSF2RB | P32927 | Cytokine receptor common subunit beta | chr22 | GO:0002443 | Not Cancer Driver | No | 204 | 0.227 | 541 | 120 | 0.222 | 0 |
| CTSC | CTSC | P53634 | Dipeptidyl peptidase 1 | chr11 | GO:0002443 | Not Cancer Driver | No | 64 | 0.138 | 19 | 5 | 0.263 | 29 |
| CTSG | CTSG | P08311 | Cathepsin G | chr14 | GO:0002443 | Not Cancer Driver | No | 65 | 0.255 | 80 | 29 | 0.362 | 0 |
| CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0002443 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
| DBH | DBH | P09172 | Dopamine beta-hydroxylase | chr9 | GO:0002443 | Not Cancer Driver | No | 125 | 0.203 | 71 | 17 | 0.239 | 3 |
| ELANE_ENST00000263621 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0002443 | Not Cancer Driver | No | 39 | 0.146 | 18 | 3 | 0.167 | 89 |
| EMP2_ENST00000536829 | EMP2 | P54851 | Epithelial membrane protein 2 | chr16 | GO:0002443 | Not Cancer Driver | No | 24 | 0.144 | 0 | 0 | 0.0 | 2 |
| EXO1_ENST00000348581 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0002443 | Not Cancer Driver | No | 123 | 0.145 | 472 | 76 | 0.161 | 0 |
| F2 | F2 | P00734 | Prothrombin | chr11 | GO:0002443 | Not Cancer Driver | No | 115 | 0.185 | 97 | 25 | 0.258 | 10 |
| FCER1G | FCER1G | P30273 | High affinity immunoglobulin epsilon receptor subunit gamma | chr1 | GO:0002443 | Not Cancer Driver | No | 10 | 0.116 | 13 | 2 | 0.154 | 0 |
| FCGR1A | FCGR1A | P12314 | High affinity immunoglobulin gamma Fc receptor I | chr1 | GO:0002443 | Not Cancer Driver | No | 62 | 0.166 | 37 | 5 | 0.135 | 0 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0002443 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FCGR3A_ENST00000443193 | FCGR3A | P08637 | Low affinity immunoglobulin gamma Fc region receptor III-A | chr1 | GO:0002443 | Not Cancer Driver | No | 69 | 0.272 | 0 | 0 | 0.0 | 1 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0002443 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GZMB | GZMB | P10144 | Granzyme B | chr14 | GO:0002443 | Not Cancer Driver | No | 49 | 0.198 | 103 | 23 | 0.223 | 0 |
| GZMM | GZMM | P51124 | Granzyme M | chr19 | GO:0002443 | Not Cancer Driver | No | 25 | 0.097 | 12 | 1 | 0.083 | 0 |
| HLA-A_ENST00000376809 | HLA-A | P04439 | HLA class I histocompatibility antigen, A alpha chain | chr6 | GO:0002443 | Census, Compendium | Yes | 128 | 0.351 | 125 | 60 | 0.48 | 0 |
| HLA-G_ENST00000360323 | HLA-G | P17693 | HLA class I histocompatibility antigen, alpha chain G | chr6 | GO:0002443 | Not Cancer Driver | No | 94 | 0.278 | 85 | 22 | 0.259 | 0 |
| HPRT1 | HPRT1 | P00492 | Hypoxanthine-guanine phosphoribosyltransferase | chrX | GO:0002443 | Not Cancer Driver | No | 22 | 0.101 | 3 | 0 | 0.0 | 62 |
| IL13RA2_ENST00000243213 | IL13RA2 | Q14627 | Interleukin-13 receptor subunit alpha-2 | chrX | GO:0002443 | Not Cancer Driver | No | 69 | 0.182 | 0 | 0 | 0.0 | 0 |
| IL18 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0002443 | Not Cancer Driver | No | 19 | 0.098 | 16 | 3 | 0.188 | 0 |
| IL21R_ENST00000395754 | IL21R | Q9HBE5 | Interleukin-21 receptor | chr16 | GO:0002443 | Census | Yes | 133 | 0.247 | 183 | 47 | 0.257 | 1 |
| IL4R_ENST00000543915 | IL4R | P24394 | Interleukin-4 receptor subunit alpha | chr16 | GO:0002443 | Not Cancer Driver | No | 133 | 0.161 | 420 | 64 | 0.152 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0002443 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IL9 | IL9 | P15248 | Interleukin-9 | chr5 | GO:0002443 | Not Cancer Driver | No | 12 | 0.083 | 4 | 0 | 0.0 | 0 |
| IL9R | IL9R | Q01113 | Interleukin-9 receptor | chrX | GO:0002443 | Not Cancer Driver | No | 96 | 0.184 | 78 | 18 | 0.231 | 0 |
| INPP5D | INPP5D | Q92835 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | chr2 | GO:0002443 | Not Cancer Driver | No | 176 | 0.148 | 578 | 90 | 0.156 | 0 |
| IRAK4_ENST00000551736 | IRAK4 | Q9NWZ3 | Interleukin-1 receptor-associated kinase 4 | chr12 | GO:0002443 | Not Cancer Driver | No | 68 | 0.148 | 116 | 20 | 0.172 | 2 |
| IRF7_ENST00000397574 | IRF7 | Q92985 | Interferon regulatory factor 7 | chr11 | GO:0002443 | Not Cancer Driver | No | 43 | 0.085 | 253 | 19 | 0.075 | 1 |
| JAGN1 | JAGN1 | Q8N5M9 | Protein jagunal homolog 1 | chr3 | GO:0002443 | Not Cancer Driver | No | 21 | 0.115 | 12 | 2 | 0.167 | 5 |
| KIF5B | KIF5B | P33176 | Kinesin-1 heavy chain | chr10 | GO:0002443 | Census, Compendium | Yes | 122 | 0.127 | 586 | 67 | 0.114 | 0 |
| KIR3DL1 | KIR3DL1 | P43629 | Killer cell immunoglobulin-like receptor 3DL1 | chr19 | GO:0002443 | Not Cancer Driver | No | 124 | 0.279 | 184 | 48 | 0.261 | 0 |
| KLRC2 | KLRC2 | P26717 | NKG2-C type II integral membrane protein | chr12 | GO:0002443 | Not Cancer Driver | No | 55 | 0.238 | 45 | 17 | 0.378 | 0 |
| KLRD1 | KLRD1 | Q13241 | Natural killer cells antigen CD94 | chr12 | GO:0002443 | Not Cancer Driver | No | 37 | 0.207 | 0 | 0 | 0.0 | 0 |
| KLRK1 | KLRK1 | P26718 | NKG2-D type II integral membrane protein | chr12 | GO:0002443 | Not Cancer Driver | No | 38 | 0.176 | 0 | 0 | 0.0 | 0 |
| KMT2E | KMT2E | Q8IZD2 | Inactive histone-lysine N-methyltransferase 2E | chr7 | GO:0002443 | Not Cancer Driver | No | 233 | 0.125 | 1613 | 198 | 0.123 | 4 |
| LYST | LYST | Q99698 | Lysosomal-trafficking regulator | chr1 | GO:0002443 | Not Cancer Driver | No | 465 | 0.122 | 608 | 87 | 0.143 | 4 |
| MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0002443 | Census | Yes | 92 | 0.099 | 37 | 4 | 0.108 | 70 |
| MYD88_ENST00000396334 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0002443 | Census, Compendium | Yes | 37 | 0.125 | 47 | 1 | 0.021 | 2 |
| NKG7 | NKG7 | Q16617 | Protein NKG7 | chr19 | GO:0002443 | Not Cancer Driver | No | 34 | 0.206 | 0 | 0 | 0.0 | 0 |
| NLRP6 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0002443 | Not Cancer Driver | No | 106 | 0.119 | 203 | 28 | 0.138 | 0 |
| PLA2G1B | PLA2G1B | P04054 | Phospholipase A2 | chr12 | GO:0002443 | Not Cancer Driver | No | 17 | 0.115 | 0 | 0 | 0.0 | 0 |
| PLEKHM2 | PLEKHM2 | Q8IWE5 | Pleckstrin homology domain-containing family M member 2 | chr1 | GO:0002443 | Not Cancer Driver | No | 96 | 0.094 | 392 | 35 | 0.089 | 0 |
| PRDX1_ENST00000319248 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | GO:0002443 | Not Cancer Driver | No | 22 | 0.111 | 40 | 5 | 0.125 | 0 |
| PRF1_ENST00000373209 | PRF1 | P14222 | Perforin-1 | chr10 | GO:0002443 | Census, Compendium | Yes | 122 | 0.22 | 145 | 36 | 0.248 | 8 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0002443 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
| PTPN6_ENST00000318974 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | GO:0002443 | Census, Compendium | Yes | 73 | 0.123 | 192 | 25 | 0.13 | 0 |
| RAET1E | RAET1E | Q8TD07 | Retinoic acid early transcript 1E | chr6 | GO:0002443 | Not Cancer Driver | No | 40 | 0.152 | 0 | 0 | 0.0 | 0 |
| RAET1G | RAET1G | Q6H3X3 | UL-16 binding protein 5 | chr6 | GO:0002443 | Not Cancer Driver | No | 41 | 0.123 | 62 | 10 | 0.161 | 0 |
| RNF19B | RNF19B | Q6ZMZ0 | E3 ubiquitin-protein ligase RNF19B | chr1 | GO:0002443 | Not Cancer Driver | No | 58 | 0.079 | 344 | 24 | 0.07 | 0 |
| SCNN1B | SCNN1B | P51168 | Amiloride-sensitive sodium channel subunit beta | chr16 | GO:0002443 | Not Cancer Driver | No | 90 | 0.141 | 62 | 4 | 0.065 | 13 |
| SERPINB9 | SERPINB9 | P50453 | Serpin B9 | chr6 | GO:0002443 | Not Cancer Driver | No | 64 | 0.17 | 22 | 2 | 0.091 | 0 |
| SLA2 | SLA2 | Q9H6Q3 | Src-like-adapter 2 | chr20 | GO:0002443 | Not Cancer Driver | No | 32 | 0.123 | 43 | 9 | 0.209 | 0 |
| SLAMF7 | SLAMF7 | Q9NQ25 | SLAM family member 7 | chr1 | GO:0002443 | Not Cancer Driver | No | 66 | 0.197 | 53 | 14 | 0.264 | 0 |
| SLAMF9 | SLAMF9 | Q96A28 | SLAM family member 9 | chr1 | GO:0002443 | Not Cancer Driver | No | 67 | 0.232 | 28 | 7 | 0.25 | 0 |
| SPON2_ENST00000431380 | SPON2 | Q9BUD6 | Spondin-2 | chr4 | GO:0002443 | Not Cancer Driver | No | 36 | 0.109 | 73 | 4 | 0.055 | 0 |
| STXBP2_ENST00000221283 | STXBP2 | Q15833 | Syntaxin-binding protein 2 | chr19 | GO:0002443 | Not Cancer Driver | No | 77 | 0.13 | 80 | 13 | 0.163 | 5 |
| TCIRG1 | TCIRG1 | Q13488 | V-type proton ATPase 116 kDa subunit a 3 | chr11 | GO:0002443 | Compendium | Yes | 68 | 0.082 | 102 | 6 | 0.059 | 5 |
| TLR8_ENST00000218032 | TLR8 | Q9NR97 | Toll-like receptor 8 | chrX | GO:0002443 | Not Cancer Driver | No | 180 | 0.173 | 30 | 7 | 0.233 | 0 |
| TRAF3IP2_ENST00000392556 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0002443 | Not Cancer Driver | No | 59 | 0.103 | 410 | 39 | 0.095 | 2 |
| TREM1 | TREM1 | Q9NP99 | Triggering receptor expressed on myeloid cells 1 | chr6 | GO:0002443 | Not Cancer Driver | No | 45 | 0.192 | 63 | 7 | 0.111 | 0 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0002443 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TUBB | TUBB | P07437 | Tubulin beta chain | chr6 | GO:0002443 | Not Cancer Driver | No | 40 | 0.09 | 63 | 11 | 0.175 | 5 |
| TUBB4B | TUBB4B | P68371 | Tubulin beta-4B chain | chr9 | GO:0002443 | Not Cancer Driver | No | 52 | 0.117 | 65 | 11 | 0.169 | 2 |
| TUSC2 | TUSC2 | O75896 | Tumor suppressor candidate 2 | chr3 | GO:0002443 | Not Cancer Driver | No | 10 | 0.091 | 31 | 3 | 0.097 | 0 |
| ULBP1 | ULBP1 | Q9BZM6 | UL16-binding protein 1 | chr6 | GO:0002443 | Not Cancer Driver | No | 48 | 0.197 | 24 | 4 | 0.167 | 0 |
| ULBP2 | ULBP2 | Q9BZM5 | UL16-binding protein 2 | chr6 | GO:0002443 | Not Cancer Driver | No | 33 | 0.134 | 25 | 2 | 0.08 | 0 |
| ULBP3 | ULBP3 | Q9BZM4 | UL16-binding protein 3 | chr6 | GO:0002443 | Not Cancer Driver | No | 34 | 0.139 | 14 | 1 | 0.071 | 0 |
| WDR1 | WDR1 | O75083 | WD repeat-containing protein 1 | chr4 | GO:0002443 | Not Cancer Driver | No | 66 | 0.109 | 30 | 7 | 0.233 | 2 |
| ZP3 | ZP3 | P21754 | Zona pellucida sperm-binding protein 3 | chr7 | GO:0002443 | Not Cancer Driver | No | 55 | 0.13 | 56 | 11 | 0.196 | 1 |