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Total number of protein in "GO:0002376" GO term:  861

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0002376 Not Cancer Driver No 260 0.176 144 22 0.153 0
ABCB9 ABCB9 Q9NP78 ABC-type oligopeptide transporter ABCB9 chr12 GO:0002376 Not Cancer Driver No 80 0.104 49 1 0.02 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0002376 Census, Compendium Yes 139 0.123 604 73 0.121 2
AC136428.1 IGHV3OR16-17 S4R3C0 Immunoglobulin heavy variable 3/OR16-17 (non-functional) (Fragment) chr16 GO:0002376 Not Cancer Driver No 42 0.362 0 0 0.0 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0002376 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0002376 Not Cancer Driver No 5 0.01 36 0 0.0 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0002376 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0002376 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0002376 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0002376 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0002376 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0002376 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0002376 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADSS ADSS2 P30520 Adenylosuccinate synthetase isozyme 2 chr1 GO:0002376 Not Cancer Driver No 49 0.107 48 4 0.083 0
ADSSL1_ENST00000330877 ADSS1 Q8N142 Adenylosuccinate synthetase isozyme 1 chr14 GO:0002376 Not Cancer Driver No 74 0.162 68 6 0.088 1
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0002376 Not Cancer Driver No 31 0.077 297 21 0.071 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0002376 Not Cancer Driver No 56 0.283 0 0 0.0 8
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0002376 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIRE AIRE O43918 Autoimmune regulator chr21 GO:0002376 Not Cancer Driver No 71 0.13 338 48 0.142 19
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 GO:0002376 Not Cancer Driver No 107 0.118 537 67 0.125 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0002376 Census, Compendium Yes 108 0.225 158 24 0.152 4
AL669918.1 AL669918.1 E7ENX8 Uncharacterized protein (Fragment) chr6 GO:0002376 Not Cancer Driver No 95 0.113 67 4 0.06 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0002376 Not Cancer Driver No 129 0.191 16 2 0.125 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0002376 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0002376 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0002376 Not Cancer Driver No 53 0.164 22 4 0.182 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0002376 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0002376 Not Cancer Driver No 138 0.12 404 59 0.146 0
APBB1IP APBB1IP Q7Z5R6 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein chr10 GO:0002376 Not Cancer Driver No 130 0.195 396 60 0.152 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0002376 Not Cancer Driver No 73 0.327 0 0 0.0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0002376 Not Cancer Driver No 77 0.194 298 65 0.218 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0002376 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0002376 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARL8B ARL8B Q9NVJ2 ADP-ribosylation factor-like protein 8B chr3 GO:0002376 Not Cancer Driver No 28 0.151 0 0 0.0 0
ARMC5_ENST00000563544 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 GO:0002376 Not Cancer Driver No 135 0.144 267 41 0.154 17
ARTN_ENST00000372354 ARTN Q5T4W7 Artemin chr1 GO:0002376 Not Cancer Driver No 11 0.05 154 6 0.039 0
ASB2 ASB2 Q96Q27 Ankyrin repeat and SOCS box protein 2 chr14 GO:0002376 Not Cancer Driver No 90 0.142 167 19 0.114 0
ATAD3A ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 GO:0002376 Not Cancer Driver No 66 0.104 269 24 0.089 2
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0002376 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0002376 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0002376 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0002376 Not Cancer Driver No 228 0.152 171 46 0.269 52
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0002376 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 GO:0002376 Not Cancer Driver No 59 0.198 41 10 0.244 0
AZI2 AZI2 Q9H6S1 5-azacytidine-induced protein 2 chr3 GO:0002376 Not Cancer Driver No 31 0.079 192 13 0.068 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0002376 Not Cancer Driver No 42 0.167 53 13 0.245 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0002376 Census, Compendium Yes 34 0.286 5 1 0.2 2
BACH2_ENST00000537989 BACH2 Q9BYV9 Transcription regulator protein BACH2 chr6 GO:0002376 Not Cancer Driver No 178 0.212 503 88 0.175 1
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0002376 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0002376 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 GO:0002376 Census, Compendium Yes 141 0.193 418 59 0.141 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0002376 Not Cancer Driver No 28 0.224 119 25 0.21 0
BATF2 BATF2 Q8N1L9 Basic leucine zipper transcriptional factor ATF-like 2 chr11 GO:0002376 Not Cancer Driver No 28 0.102 202 19 0.094 0
BATF3 BATF3 Q9NR55 Basic leucine zipper transcriptional factor ATF-like 3 chr1 GO:0002376 Not Cancer Driver No 18 0.142 127 18 0.142 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0002376 Census Yes 30 0.156 39 2 0.051 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0002376 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0002376 Census, Compendium Yes 156 0.174 699 114 0.163 2
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0002376 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0002376 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0002376 Census Yes 44 0.097 259 23 0.089 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0002376 Census, Compendium Yes 134 0.19 328 67 0.204 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0002376 Not Cancer Driver No 94 0.186 75 21 0.28 0
BPIFA1_ENST00000375413 BPIFA1 Q9NP55 BPI fold-containing family A member 1 chr20 GO:0002376 Not Cancer Driver No 54 0.211 0 0 0.0 0
BPIFB1 BPIFB1 Q8TDL5 BPI fold-containing family B member 1 chr20 GO:0002376 Not Cancer Driver No 93 0.192 7 0 0.0 0
BSG BSG P35613 Basigin chr19 GO:0002376 Not Cancer Driver No 43 0.112 123 17 0.138 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0002376 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN3A1 BTN3A1 O00481 Butyrophilin subfamily 3 member A1 chr6 GO:0002376 Not Cancer Driver No 77 0.15 72 18 0.25 0
C10orf99 GPR15L Q6UWK7 Protein GPR15L chr10 GO:0002376 Not Cancer Driver No 11 0.136 0 0 0.0 0
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0002376 Not Cancer Driver No 16 0.06 84 3 0.036 0
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 GO:0002376 Not Cancer Driver No 41 0.167 124 16 0.129 0
C1QB C1QB P02746 Complement C1q subcomponent subunit B chr1 GO:0002376 Not Cancer Driver No 46 0.182 133 31 0.233 1
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0002376 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QC C1QC P02747 Complement C1q subcomponent subunit C chr1 GO:0002376 Not Cancer Driver No 46 0.188 134 26 0.194 1
C1R C1R P00736 Complement C1r subcomponent chr12 GO:0002376 Not Cancer Driver No 88 0.125 51 6 0.118 6
C1RL C1RL Q9NZP8 Complement C1r subcomponent-like protein chr12 GO:0002376 Not Cancer Driver No 60 0.123 146 22 0.151 0
C1S C1S P09871 Complement C1s subcomponent chr12 GO:0002376 Not Cancer Driver No 128 0.186 97 21 0.216 1
C2 C2 P06681 Complement C2 chr6 GO:0002376 Not Cancer Driver No 120 0.16 120 17 0.142 3
C3 C3 P01024 Complement C3 chr19 GO:0002376 Not Cancer Driver No 337 0.203 287 50 0.174 12
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0002376 Not Cancer Driver No 88 0.183 72 16 0.222 0
C4A C4A P0C0L4 Complement C4-A chr6 GO:0002376 Not Cancer Driver No 43 0.025 309 6 0.019 0
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 GO:0002376 Not Cancer Driver No 109 0.183 40 10 0.25 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 GO:0002376 Not Cancer Driver No 40 0.159 0 0 0.0 0
C5 C5 P01031 Complement C5 chr9 GO:0002376 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0002376 Not Cancer Driver No 71 0.203 0 0 0.0 0
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 GO:0002376 Not Cancer Driver No 60 0.178 11 3 0.273 0
C6 C6 P13671 Complement component C6 chr5 GO:0002376 Not Cancer Driver No 346 0.37 121 47 0.388 0
C7 C7 P10643 Complement component C7 chr5 GO:0002376 Not Cancer Driver No 291 0.345 89 37 0.416 5
C8A C8A P07357 Complement component C8 alpha chain chr1 GO:0002376 Not Cancer Driver No 176 0.301 25 9 0.36 0
C8B C8B P07358 Complement component C8 beta chain chr1 GO:0002376 Not Cancer Driver No 186 0.315 29 11 0.379 0
C8G C8G P07360 Complement component C8 gamma chain chr9 GO:0002376 Not Cancer Driver No 10 0.05 26 2 0.077 0
C9 C9 P02748 Complement component C9 chr5 GO:0002376 Not Cancer Driver No 156 0.279 40 8 0.2 2
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0002376 Not Cancer Driver No 106 0.24 103 28 0.272 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0002376 Not Cancer Driver No 101 0.214 127 30 0.236 0
CAMLG CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 GO:0002376 Not Cancer Driver No 32 0.108 157 16 0.102 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0002376 Not Cancer Driver No 25 0.147 48 4 0.083 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0002376 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0002376 Not Cancer Driver No 53 0.099 126 7 0.056 1
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0002376 Not Cancer Driver No 72 0.134 225 35 0.156 11
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0002376 Census Yes 32 0.116 62 5 0.081 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0002376 Census, Compendium Yes 142 0.296 106 12 0.113 1
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0002376 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0002376 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0002376 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0002376 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCL13 CCL13 Q99616 C-C motif chemokine 13 chr17 GO:0002376 Not Cancer Driver No 15 0.153 1 0 0.0 0
CCL17_ENST00000616880 CCL17 Q92583 C-C motif chemokine 17 chr16 GO:0002376 Not Cancer Driver No 10 0.106 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0002376 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0002376 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL20 CCL20 P78556 C-C motif chemokine 20 chr2 GO:0002376 Not Cancer Driver No 16 0.167 0 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0002376 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL22 CCL22 O00626 C-C motif chemokine 22 chr16 GO:0002376 Not Cancer Driver No 19 0.204 0 0 0.0 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0002376 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 GO:0002376 Not Cancer Driver No 20 0.133 26 6 0.231 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0002376 Not Cancer Driver No 9 0.096 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0002376 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCL8 CCL8 P80075 C-C motif chemokine 8 chr17 GO:0002376 Not Cancer Driver No 17 0.172 0 0 0.0 0
CCNB2 CCNB2 O95067 G2/mitotic-specific cyclin-B2 chr15 GO:0002376 Not Cancer Driver No 33 0.083 103 10 0.097 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0002376 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0002376 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR4 CCR4 P51679 C-C chemokine receptor type 4 chr3 GO:0002376 Census Yes 45 0.125 0 0 0.0 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0002376 Not Cancer Driver No 107 0.304 0 0 0.0 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0002376 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0002376 Census, Compendium Yes 50 0.132 0 0 0.0 0
CCR9 CCR9 P51686 C-C chemokine receptor type 9 chr3 GO:0002376 Not Cancer Driver No 60 0.163 0 0 0.0 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0002376 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 GO:0002376 Not Cancer Driver No 71 0.162 79 26 0.329 0
CD180 CD180 Q99467 CD180 antigen chr5 GO:0002376 Not Cancer Driver No 105 0.159 0 0 0.0 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0002376 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD1A CD1A P06126 T-cell surface glycoprotein CD1a chr1 GO:0002376 Not Cancer Driver No 105 0.321 18 6 0.333 0
CD1B CD1B P29016 T-cell surface glycoprotein CD1b chr1 GO:0002376 Not Cancer Driver No 97 0.291 7 0 0.0 0
CD1C CD1C P29017 T-cell surface glycoprotein CD1c chr1 GO:0002376 Not Cancer Driver No 127 0.381 1 0 0.0 0
CD1D CD1D P15813 Antigen-presenting glycoprotein CD1d chr1 GO:0002376 Not Cancer Driver No 93 0.278 19 7 0.368 0
CD1E CD1E P15812 T-cell surface glycoprotein CD1e, membrane-associated chr1 GO:0002376 Not Cancer Driver No 158 0.407 21 11 0.524 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0002376 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0002376 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0002376 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0002376 Census Yes 29 0.1 54 9 0.167 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0002376 Census Yes 42 0.191 18 10 0.556 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0002376 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD300C CD300C Q08708 CMRF35-like molecule 6 chr17 GO:0002376 Not Cancer Driver No 67 0.299 85 24 0.282 0
CD300E CD300E Q496F6 CMRF35-like molecule 2 chr17 GO:0002376 Not Cancer Driver No 55 0.268 38 11 0.289 0
CD300LB CD300LB A8K4G0 CMRF35-like molecule 7 chr17 GO:0002376 Not Cancer Driver No 48 0.239 65 15 0.231 0
CD300LD CD300LD Q6UXZ3 CMRF35-like molecule 5 chr17 GO:0002376 Not Cancer Driver No 27 0.139 33 2 0.061 0
CD300LF_ENST00000326165 CD300LF Q8TDQ1 CMRF35-like molecule 1 chr17 GO:0002376 Not Cancer Driver No 36 0.124 88 11 0.125 0
CD300LG CD300LG Q6UXG3 CMRF35-like molecule 9 chr17 GO:0002376 Not Cancer Driver No 65 0.196 170 37 0.218 0
CD320 CD320 Q9NPF0 CD320 antigen chr19 GO:0002376 Not Cancer Driver No 30 0.106 82 9 0.11 0
CD3D CD3D P04234 T-cell surface glycoprotein CD3 delta chain chr11 GO:0002376 Not Cancer Driver No 23 0.135 2 1 0.5 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0002376 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD3G CD3G P09693 T-cell surface glycoprotein CD3 gamma chain chr11 GO:0002376 Not Cancer Driver No 25 0.137 48 7 0.146 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0002376 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0002376 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD40LG CD40LG P29965 CD40 ligand chrX GO:0002376 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0002376 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD5 CD5 P06127 T-cell surface glycoprotein CD5 chr11 GO:0002376 Not Cancer Driver No 67 0.135 146 19 0.13 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0002376 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD5L CD5L O43866 CD5 antigen-like chr1 GO:0002376 Not Cancer Driver No 145 0.418 33 13 0.394 0
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0002376 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD68 CD68 P34810 Macrosialin chr17 GO:0002376 Not Cancer Driver No 26 0.073 192 13 0.068 0
CD70_ENST00000245903 CD70 P32970 CD70 antigen chr19 GO:0002376 Not Cancer Driver No 33 0.171 11 2 0.182 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0002376 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0002376 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0002376 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0002376 Not Cancer Driver No 90 0.274 56 18 0.321 0
CD8A_ENST00000283635 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 GO:0002376 Not Cancer Driver No 33 0.14 28 2 0.071 1
CD93 CD93 Q9NPY3 Complement component C1q receptor chr20 GO:0002376 Not Cancer Driver No 145 0.222 195 49 0.251 0
CD99 CD99 P14209 CD99 antigen chrX GO:0002376 Not Cancer Driver No 22 0.119 143 19 0.133 0
CD99L2_ENST00000370377 CD99L2 Q8TCZ2 CD99 antigen-like protein 2 chrX GO:0002376 Not Cancer Driver No 57 0.218 193 47 0.244 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0002376 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH17 CDH17 Q12864 Cadherin-17 chr8 GO:0002376 Census Yes 166 0.2 186 35 0.188 0
CDH26 CDH26 Q8IXH8 Cadherin-like protein 26 chr20 GO:0002376 Not Cancer Driver No 157 0.189 296 48 0.162 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0002376 Census Yes 40 0.123 24 3 0.125 1
CEACAM20 CEACAM20 Q6UY09 Carcinoembryonic antigen-related cell adhesion molecule 20 chr19 GO:0002376 Not Cancer Driver No 86 0.144 182 30 0.165 0
CEBPG_ENST00000585933 CEBPG P53567 CCAAT/enhancer-binding protein gamma chr19 GO:0002376 Not Cancer Driver No 13 0.087 141 12 0.085 0
CFB CFB P00751 Complement factor B chr6 GO:0002376 Not Cancer Driver No 75 0.098 112 20 0.179 7
CFD_ENST00000327726 CFD P00746 Complement factor D chr19 GO:0002376 Not Cancer Driver No 6 0.024 69 3 0.043 2
CFH CFH P08603 Complement factor H chr1 GO:0002376 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFHR5 CFHR5 Q9BXR6 Complement factor H-related protein 5 chr1 GO:0002376 Not Cancer Driver No 162 0.285 40 9 0.225 0
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 GO:0002376 Not Cancer Driver No 97 0.166 4 0 0.0 13
CFP CFP P27918 Properdin chrX GO:0002376 Not Cancer Driver No 60 0.128 48 7 0.146 6
CH25H CH25H O95992 Cholesterol 25-hydroxylase chr10 GO:0002376 Not Cancer Driver No 37 0.136 0 0 0.0 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0002376 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHIA_ENST00000343320 CHIA Q9BZP6 Acidic mammalian chitinase chr1 GO:0002376 Not Cancer Driver No 116 0.244 42 10 0.238 0
CKLF CKLF Q9UBR5 Chemokine-like factor chr16 GO:0002376 Not Cancer Driver No 20 0.132 0 0 0.0 0
CLEC2A CLEC2A Q6UVW9 C-type lectin domain family 2 member A chr12 GO:0002376 Not Cancer Driver No 10 0.057 0 0 0.0 0
CLEC4A CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 GO:0002376 Not Cancer Driver No 35 0.148 22 4 0.182 0
CLEC4C_ENST00000360345 CLEC4C Q8WTT0 C-type lectin domain family 4 member C chr12 GO:0002376 Not Cancer Driver No 58 0.272 5 1 0.2 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0002376 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 GO:0002376 Not Cancer Driver No 56 0.256 5 2 0.4 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0002376 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0002376 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0002376 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 GO:0002376 Not Cancer Driver No 69 0.098 224 25 0.112 11
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0002376 Not Cancer Driver No 69 0.154 156 27 0.173 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0002376 Not Cancer Driver No 107 0.287 24 13 0.542 0
CMTM7 CMTM7 Q96FZ5 CKLF-like MARVEL transmembrane domain-containing protein 7 chr3 GO:0002376 Not Cancer Driver No 25 0.143 0 0 0.0 0
COLEC10 COLEC10 Q9Y6Z7 Collectin-10 chr8 GO:0002376 Not Cancer Driver No 58 0.209 95 23 0.242 1
COLEC11_ENST00000349077 COLEC11 Q9BWP8 Collectin-11 chr2 GO:0002376 Not Cancer Driver No 72 0.266 158 40 0.253 2
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0002376 Not Cancer Driver No 51 0.111 126 15 0.119 1
CPLX2_ENST00000515094 CPLX2 Q6PUV4 Complexin-2 chr5 GO:0002376 Not Cancer Driver No 27 0.201 134 27 0.201 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0002376 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0002376 Not Cancer Driver No 273 0.264 85 28 0.329 0
CRACR2A CRACR2A Q9BSW2 EF-hand calcium-binding domain-containing protein 4B chr12 GO:0002376 Not Cancer Driver No 88 0.12 436 60 0.138 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0002376 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CRK CRK P46108 Adapter molecule crk chr17 GO:0002376 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0002376 Not Cancer Driver No 38 0.125 160 25 0.156 0
CRP CRP P02741 C-reactive protein chr1 GO:0002376 Not Cancer Driver No 59 0.263 0 0 0.0 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0002376 Not Cancer Driver No 64 0.163 135 14 0.104 0
CRTC3 CRTC3 Q6UUV7 CREB-regulated transcription coactivator 3 chr15 GO:0002376 Census Yes 70 0.113 608 68 0.112 0
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0002376 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0002376 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 GO:0002376 Not Cancer Driver No 204 0.227 541 120 0.222 0
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 GO:0002376 Census, Compendium Yes 131 0.157 209 34 0.163 2
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0002376 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0002376 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 GO:0002376 Not Cancer Driver No 72 0.128 158 24 0.152 0
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:0002376 Not Cancer Driver No 64 0.138 19 5 0.263 29
CTSD CTSD P07339 Cathepsin D chr11 GO:0002376 Not Cancer Driver No 57 0.138 6 1 0.167 2
CTSE CTSE P14091 Cathepsin E chr1 GO:0002376 Not Cancer Driver No 59 0.149 23 2 0.087 0
CTSF CTSF Q9UBX1 Cathepsin F chr11 GO:0002376 Not Cancer Driver No 63 0.13 78 7 0.09 4
CTSG CTSG P08311 Cathepsin G chr14 GO:0002376 Not Cancer Driver No 65 0.255 80 29 0.362 0
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0002376 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSL CTSL P07711 Procathepsin L chr9 GO:0002376 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSS CTSS P25774 Cathepsin S chr1 GO:0002376 Not Cancer Driver No 54 0.163 0 0 0.0 0
CTSV CTSV O60911 Cathepsin L2 chr9 GO:0002376 Not Cancer Driver No 55 0.165 7 1 0.143 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0002376 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0002376 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 GO:0002376 Not Cancer Driver No 51 0.14 98 19 0.194 0
CXCL1 CXCL1 P09341 Growth-regulated alpha protein chr4 GO:0002376 Not Cancer Driver No 20 0.187 18 4 0.222 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0002376 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL11 CXCL11 O14625 C-X-C motif chemokine 11 chr4 GO:0002376 Not Cancer Driver No 13 0.138 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0002376 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL2 CXCL2 P19875 C-X-C motif chemokine 2 chr4 GO:0002376 Not Cancer Driver No 11 0.103 15 5 0.333 0
CXCL3 CXCL3 P19876 C-X-C motif chemokine 3 chr4 GO:0002376 Not Cancer Driver No 11 0.103 8 0 0.0 0
CXCL5 CXCL5 P42830 C-X-C motif chemokine 5 chr4 GO:0002376 Not Cancer Driver No 25 0.219 1 0 0.0 0
CXCL6 CXCL6 P80162 C-X-C motif chemokine 6 chr4 GO:0002376 Not Cancer Driver No 17 0.149 9 1 0.111 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0002376 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0002376 Not Cancer Driver No 32 0.256 38 16 0.421 0
CXCR1 CXCR1 P25024 C-X-C chemokine receptor type 1 chr2 GO:0002376 Not Cancer Driver No 71 0.203 0 0 0.0 0
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 GO:0002376 Not Cancer Driver No 87 0.242 8 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0002376 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYBC1_ENST00000577732 CYBC1 Q9BQA9 Cytochrome b-245 chaperone 1 chr17 GO:0002376 Not Cancer Driver No 22 0.118 17 2 0.118 0
CYP7B1 CYP7B1 O75881 Cytochrome P450 7B1 chr8 GO:0002376 Not Cancer Driver No 133 0.263 0 0 0.0 11
CYREN CYREN Q9BWK5 Cell cycle regulator of non-homologous end joining chr7 GO:0002376 Not Cancer Driver No 24 0.153 128 19 0.148 0
CYSLTR1 CYSLTR1 Q9Y271 Cysteinyl leukotriene receptor 1 chrX GO:0002376 Not Cancer Driver No 58 0.172 8 1 0.125 0
DCAF15 DCAF15 Q66K64 DDB1- and CUL4-associated factor 15 chr19 GO:0002376 Not Cancer Driver No 50 0.083 173 18 0.104 0
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0002376 Compendium Yes 150 0.319 6 3 0.5 0
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 GO:0002376 Not Cancer Driver No 91 0.125 362 48 0.133 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0002376 Not Cancer Driver No 118 0.128 61 10 0.164 2
DEFA3 DEFA3 P59666 Neutrophil defensin 3 chr8 GO:0002376 Not Cancer Driver No 15 0.16 0 0 0.0 0
DEFA4 DEFA4 P12838 Defensin alpha 4 chr8 GO:0002376 Not Cancer Driver No 35 0.361 17 5 0.294 0
DEFA5 DEFA5 Q01523 Defensin-5 chr8 GO:0002376 Not Cancer Driver No 16 0.17 17 3 0.176 0
DEFA6 DEFA6 Q01524 Defensin-6 chr8 GO:0002376 Not Cancer Driver No 19 0.19 15 2 0.133 0
DEFB1 DEFB1 P60022 Beta-defensin 1 chr8 GO:0002376 Not Cancer Driver No 8 0.118 0 0 0.0 0
DEFB104B DEFB104B Q8WTQ1 Beta-defensin 104 chr8 GO:0002376 Not Cancer Driver No 1 0.014 0 0 0.0 0
DEFB106B DEFB106B Q8N104 Beta-defensin 106 chr8 GO:0002376 Not Cancer Driver No 15 0.231 0 0 0.0 0
DEFB114 DEFB114 Q30KQ6 Beta-defensin 114 chr6 GO:0002376 Not Cancer Driver No 31 0.449 0 0 0.0 0
DEFB119_ENST00000376321 DEFB119 Q8N690 Beta-defensin 119 chr20 GO:0002376 Not Cancer Driver No 25 0.298 0 0 0.0 0
DHRS2_ENST00000250383 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 GO:0002376 Not Cancer Driver No 47 0.168 0 0 0.0 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0002376 Not Cancer Driver No 115 0.159 145 24 0.166 1
DMBT1_ENST00000619379 DMBT1 Q9UGM3 Deleted in malignant brain tumors 1 protein chr10 GO:0002376 Not Cancer Driver No 506 0.21 404 64 0.158 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 GO:0002376 Not Cancer Driver No 50 0.104 152 21 0.138 0
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0002376 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE1_ENST00000246949 DNASE1 P24855 Deoxyribonuclease-1 chr16 GO:0002376 Not Cancer Driver No 24 0.085 0 0 0.0 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0002376 Census Yes 138 0.159 270 43 0.159 22
DOCK10 DOCK10 Q96BY6 Dedicator of cytokinesis protein 10 chr2 GO:0002376 Not Cancer Driver No 368 0.168 409 58 0.142 0
DOCK11 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX GO:0002376 Not Cancer Driver No 312 0.151 240 29 0.121 0
DOCK2 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 GO:0002376 Not Cancer Driver No 480 0.262 266 79 0.297 2
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0002376 Not Cancer Driver No 321 0.153 312 60 0.192 1
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0002376 Not Cancer Driver No 151 0.197 8 1 0.125 0
DYSF_ENST00000258104 DYSF O75923 Dysferlin chr2 GO:0002376 Not Cancer Driver No 467 0.225 329 64 0.195 55
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0002376 Not Cancer Driver No 32 0.14 10 1 0.1 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0002376 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0002376 Not Cancer Driver No 21 0.118 87 13 0.149 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0002376 Not Cancer Driver No 69 0.29 140 44 0.314 3
EFNB1 EFNB1 P98172 Ephrin-B1 chrX GO:0002376 Not Cancer Driver No 46 0.133 126 14 0.111 19
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0002376 Not Cancer Driver No 42 0.126 97 15 0.155 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0002376 Not Cancer Driver No 45 0.132 183 22 0.12 0
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0002376 Not Cancer Driver No 39 0.146 18 3 0.167 89
ELF4 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX GO:0002376 Census, Compendium Yes 88 0.133 486 60 0.123 0
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0002376 Not Cancer Driver No 24 0.144 0 0 0.0 2
ENPP3_ENST00000357639 ENPP3 O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 chr6 GO:0002376 Not Cancer Driver No 146 0.167 57 12 0.211 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0002376 Not Cancer Driver No 90 0.149 26 3 0.115 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0002376 Not Cancer Driver No 82 0.12 436 50 0.115 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0002376 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0002376 Not Cancer Driver No 106 0.129 459 54 0.118 0
EPX EPX P11678 Eosinophil peroxidase chr17 GO:0002376 Not Cancer Driver No 144 0.201 55 6 0.109 1
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 GO:0002376 Not Cancer Driver No 78 0.083 70 2 0.029 0
ERAP2 ERAP2 Q6P179 Endoplasmic reticulum aminopeptidase 2 chr5 GO:0002376 Not Cancer Driver No 97 0.101 23 4 0.174 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0002376 Not Cancer Driver No 42 0.141 105 14 0.133 1
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0002376 Not Cancer Driver No 123 0.145 472 76 0.161 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0002376 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0002376 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0002376 Census Yes 107 0.143 58 7 0.121 12
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0002376 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2 F2 P00734 Prothrombin chr11 GO:0002376 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0002376 Not Cancer Driver No 55 0.139 7 2 0.286 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0002376 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0002376 Not Cancer Driver No 27 0.117 48 9 0.188 0
FANCC FANCC Q00597 Fanconi anemia group C protein chr9 GO:0002376 Census, Compendium Yes 66 0.118 13 1 0.077 3
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0002376 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0002376 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCGR2A FCGR2A P12318 Low affinity immunoglobulin gamma Fc region receptor II-a chr1 GO:0002376 Not Cancer Driver No 64 0.202 133 28 0.211 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0002376 Census Yes 51 0.165 99 30 0.303 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 GO:0002376 Not Cancer Driver No 69 0.272 0 0 0.0 1
FCMR FCMR O60667 Fas apoptotic inhibitory molecule 3 chr1 GO:0002376 Not Cancer Driver No 55 0.141 229 29 0.127 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0002376 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:0002376 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0002376 Not Cancer Driver No 46 0.154 65 19 0.292 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0002376 Not Cancer Driver No 114 0.139 145 21 0.145 0
FER1L5 FER1L5 A0AVI2 Fer-1-like protein 5 chr2 GO:0002376 Not Cancer Driver No 154 0.075 200 11 0.055 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0002376 Not Cancer Driver No 49 0.148 32 7 0.219 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0002376 Not Cancer Driver No 78 0.225 29 6 0.207 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0002376 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0002376 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0002376 Not Cancer Driver No 71 0.162 70 12 0.171 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0002376 Not Cancer Driver No 85 0.161 52 8 0.154 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0002376 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0002376 Census, Compendium Yes 200 0.201 64 27 0.422 0
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0002376 Not Cancer Driver No 143 0.123 384 44 0.115 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0002376 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0002376 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:0002376 Not Cancer Driver No 90 0.139 483 65 0.135 2
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0002376 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0002376 Not Cancer Driver No 38 0.088 186 16 0.086 10
FPR1_ENST00000304748 FPR1 P21462 fMet-Leu-Phe receptor chr19 GO:0002376 Not Cancer Driver No 99 0.283 18 3 0.167 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0002376 Not Cancer Driver No 96 0.274 26 5 0.192 0
FPR3 FPR3 P25089 N-formyl peptide receptor 3 chr19 GO:0002376 Not Cancer Driver No 82 0.232 28 2 0.071 0
FUT4 FUT4 P22083 Alpha-(1,3)-fucosyltransferase 4 chr11 GO:0002376 Not Cancer Driver No 49 0.092 193 9 0.047 0
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0002376 Not Cancer Driver No 28 0.082 25 3 0.12 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0002376 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0002376 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0002376 Not Cancer Driver No 90 0.157 22 2 0.091 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0002376 Not Cancer Driver No 72 0.104 146 3 0.021 0
GAPT GAPT Q8N292 Protein GAPT chr5 GO:0002376 Not Cancer Driver No 41 0.261 83 27 0.325 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0002376 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0002376 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0002376 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 GO:0002376 Not Cancer Driver No 216 0.116 669 76 0.114 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0002376 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0002376 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0002376 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR15 GPR15 P49685 G-protein coupled receptor 15 chr3 GO:0002376 Not Cancer Driver No 73 0.203 0 0 0.0 0
GPR174_ENST00000276077 GPR174 Q9BXC1 Probable G-protein coupled receptor 174 chrX GO:0002376 Not Cancer Driver No 115 0.345 0 0 0.0 0
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0002376 Not Cancer Driver No 53 0.147 25 3 0.12 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0002376 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR32 GPR32 O75388 Probable G-protein coupled receptor 32 chr19 GO:0002376 Not Cancer Driver No 85 0.239 18 6 0.333 0
GRN GRN P28799 Progranulin chr17 GO:0002376 Not Cancer Driver No 76 0.128 29 6 0.207 1
GZMB GZMB P10144 Granzyme B chr14 GO:0002376 Not Cancer Driver No 49 0.198 103 23 0.223 0
GZMM GZMM P51124 Granzyme M chr19 GO:0002376 Not Cancer Driver No 25 0.097 12 1 0.083 0
H2BFS H2BC12L P57053 Histone H2B type F-S chr21 GO:0002376 Not Cancer Driver No 1 0.008 86 1 0.012 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0002376 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0002376 Not Cancer Driver No 69 0.229 17 2 0.118 3
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0002376 Not Cancer Driver No 112 0.213 124 25 0.202 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 GO:0002376 Not Cancer Driver No 274 0.105 991 108 0.109 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0002376 Not Cancer Driver No 55 0.158 27 2 0.074 11
HHLA2_ENST00000489514 HHLA2 Q9UM44 HERV-H LTR-associating protein 2 chr3 GO:0002376 Not Cancer Driver No 85 0.205 57 10 0.175 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0002376 Census Yes 118 0.143 435 51 0.117 0
HIST1H2BC H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0002376 Not Cancer Driver No 53 0.421 79 27 0.342 0
HIST1H2BE H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0002376 Not Cancer Driver No 26 0.206 79 16 0.203 0
HIST1H2BF H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0002376 Not Cancer Driver No 30 0.238 79 20 0.253 0
HIST1H2BG H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0002376 Not Cancer Driver No 45 0.357 79 25 0.316 0
HIST1H2BI H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0002376 Not Cancer Driver No 30 0.238 79 18 0.228 0
HIST1H2BJ_ENST00000339812 H2BC11 P06899 Histone H2B type 1-J chr6 GO:0002376 Not Cancer Driver No 22 0.175 75 13 0.173 0
HIST1H2BK H2BC12 O60814 Histone H2B type 1-K chr6 GO:0002376 Not Cancer Driver No 42 0.333 78 29 0.372 0
HIST2H2BE H2BC21 Q16778 Histone H2B type 2-E chr1 GO:0002376 Not Cancer Driver No 47 0.373 77 30 0.39 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0002376 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0002376 Compendium Yes 78 0.215 169 34 0.201 0
HLA-C HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 GO:0002376 Not Cancer Driver No 104 0.284 175 58 0.331 0
HLA-DMA HLA-DMA P28067 HLA class II histocompatibility antigen, DM alpha chain chr6 GO:0002376 Not Cancer Driver No 27 0.103 16 2 0.125 0
HLA-DMB HLA-DMB P28068 HLA class II histocompatibility antigen, DM beta chain chr6 GO:0002376 Not Cancer Driver No 41 0.156 41 9 0.22 0
HLA-DOA HLA-DOA P06340 HLA class II histocompatibility antigen, DO alpha chain chr6 GO:0002376 Not Cancer Driver No 39 0.156 7 1 0.143 0
HLA-DOB HLA-DOB P13765 HLA class II histocompatibility antigen, DO beta chain chr6 GO:0002376 Not Cancer Driver No 34 0.125 9 2 0.222 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 GO:0002376 Not Cancer Driver No 37 0.142 30 4 0.133 0
HLA-DPB1 HLA-DPB1 P04440 HLA class II histocompatibility antigen, DP beta 1 chain chr6 GO:0002376 Not Cancer Driver No 38 0.147 39 4 0.103 0
HLA-DQA2 HLA-DQA2 P01906 HLA class II histocompatibility antigen, DQ alpha 2 chain chr6 GO:0002376 Not Cancer Driver No 61 0.239 7 0 0.0 0
HLA-DQB2 HLA-DQB2 P05538 HLA class II histocompatibility antigen, DQ beta 2 chain chr6 GO:0002376 Not Cancer Driver No 55 0.205 38 5 0.132 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0002376 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0002376 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-DRB5 HLA-DRB5 Q30154 HLA class II histocompatibility antigen, DR beta 5 chain chr6 GO:0002376 Not Cancer Driver No 35 0.132 18 2 0.111 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0002376 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0002376 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0002376 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0002376 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0002376 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0002376 Not Cancer Driver No 46 0.16 81 13 0.16 0
HOXB6_ENST00000225648 HOXB6 P17509 Homeobox protein Hox-B6 chr17 GO:0002376 Not Cancer Driver No 31 0.138 103 20 0.194 0
HP HP P00738 Haptoglobin chr16 GO:0002376 Not Cancer Driver No 39 0.096 57 2 0.035 1
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0002376 Not Cancer Driver No 22 0.101 3 0 0.0 62
HRAS HRAS P01112 GTPase HRas chr11 GO:0002376 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0002376 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 GO:0002376 Not Cancer Driver No 43 0.117 27 5 0.185 2
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0002376 Not Cancer Driver No 61 0.106 82 6 0.073 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0002376 Not Cancer Driver No 52 0.11 8 1 0.125 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0002376 Not Cancer Driver No 61 0.115 251 28 0.112 0
ICOS ICOS Q9Y6W8 Inducible T-cell costimulator chr2 GO:0002376 Not Cancer Driver No 36 0.181 0 0 0.0 0
IDE IDE P14735 Insulin-degrading enzyme chr10 GO:0002376 Not Cancer Driver No 90 0.088 96 8 0.083 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0002376 Not Cancer Driver No 82 0.203 41 8 0.195 0
IDO2 IDO2 Q6ZQW0 Indoleamine 2,3-dioxygenase 2 chr8 GO:0002376 Not Cancer Driver No 93 0.221 35 5 0.143 0
IFI30 IFI30 P13284 Gamma-interferon-inducible lysosomal thiol reductase chr19 GO:0002376 Not Cancer Driver No 22 0.088 16 2 0.125 0
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 GO:0002376 Not Cancer Driver No 33 0.115 63 10 0.159 0
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0002376 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0002376 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0002376 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0002376 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0002376 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0002376 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0002376 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0002376 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0002376 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0002376 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0002376 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0002376 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0002376 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0002376 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0002376 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0002376 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 GO:0002376 Compendium Yes 55 0.112 175 22 0.126 10
IFNGR2_ENST00000290219 IFNGR2 P38484 Interferon gamma receptor 2 chr21 GO:0002376 Not Cancer Driver No 36 0.107 18 2 0.111 5
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0002376 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNL2 IFNL2 Q8IZJ0 Interferon lambda-2 chr19 GO:0002376 Not Cancer Driver No 38 0.19 5 0 0.0 0
IFNLR1 IFNLR1 Q8IU57 Interferon lambda receptor 1 chr1 GO:0002376 Not Cancer Driver No 57 0.11 256 33 0.129 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0002376 Not Cancer Driver No 32 0.164 10 3 0.3 0
IGHD IGHD P01880 Immunoglobulin heavy constant delta chr14 GO:0002376 Not Cancer Driver No 61 0.159 245 40 0.163 0
IGLL1 IGLL1 P15814 Immunoglobulin lambda-like polypeptide 1 chr22 GO:0002376 Not Cancer Driver No 25 0.117 144 18 0.125 1
IGLL5 IGLL5 B9A064 Immunoglobulin lambda-like polypeptide 5 chr22 GO:0002376 Not Cancer Driver No 59 0.276 127 35 0.276 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0002376 Census, Compendium Yes 106 0.14 211 31 0.147 1
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0002376 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0002376 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX GO:0002376 Not Cancer Driver No 69 0.182 0 0 0.0 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0002376 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17RA IL17RA Q96F46 Interleukin-17 receptor A chr22 GO:0002376 Not Cancer Driver No 92 0.106 301 20 0.066 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0002376 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18BP_ENST00000337131 IL18BP O95998 Interleukin-18-binding protein chr11 GO:0002376 Not Cancer Driver No 16 0.082 50 6 0.12 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0002376 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0002376 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1F10_ENST00000341010 IL1F10 Q8WWZ1 Interleukin-1 family member 10 chr2 GO:0002376 Not Cancer Driver No 30 0.197 10 1 0.1 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0002376 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0002376 Census Yes 24 0.157 6 1 0.167 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0002376 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0002376 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL21R_ENST00000395754 IL21R Q9HBE5 Interleukin-21 receptor chr16 GO:0002376 Census Yes 133 0.247 183 47 0.257 1
IL25 IL25 Q9H293 Interleukin-25 chr14 GO:0002376 Not Cancer Driver No 30 0.169 50 8 0.16 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0002376 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL2RB IL2RB P14784 Interleukin-2 receptor subunit beta chr22 GO:0002376 Not Cancer Driver No 81 0.147 182 33 0.181 1
IL31 IL31 Q6EBC2 Interleukin-31 chr12 GO:0002376 Not Cancer Driver No 19 0.116 25 4 0.16 0
IL31RA_ENST00000297015 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0002376 Not Cancer Driver No 117 0.16 163 30 0.184 1
IL36A IL36A Q9UHA7 Interleukin-36 alpha chr2 GO:0002376 Not Cancer Driver No 44 0.278 13 3 0.231 0
IL36B IL36B Q9NZH7 Interleukin-36 beta chr2 GO:0002376 Not Cancer Driver No 53 0.323 32 8 0.25 0
IL36G IL36G Q9NZH8 Interleukin-36 gamma chr2 GO:0002376 Not Cancer Driver No 35 0.207 23 5 0.217 0
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0002376 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL37 IL37 Q9NZH6 Interleukin-37 chr2 GO:0002376 Not Cancer Driver No 56 0.257 71 13 0.183 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0002376 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0002376 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 GO:0002376 Not Cancer Driver No 92 0.219 23 5 0.217 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0002376 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0002376 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL9 IL9 P15248 Interleukin-9 chr5 GO:0002376 Not Cancer Driver No 12 0.083 4 0 0.0 0
IL9R IL9R Q01113 Interleukin-9 receptor chrX GO:0002376 Not Cancer Driver No 96 0.184 78 18 0.231 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0002376 Not Cancer Driver No 176 0.148 578 90 0.156 0
INPPL1 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 GO:0002376 Not Cancer Driver No 174 0.138 566 76 0.134 4
INS INS P01308 Insulin chr11 GO:0002376 Not Cancer Driver No 15 0.136 5 1 0.2 22
IRAK4_ENST00000551736 IRAK4 Q9NWZ3 Interleukin-1 receptor-associated kinase 4 chr12 GO:0002376 Not Cancer Driver No 68 0.148 116 20 0.172 2
IREB2 IREB2 P48200 Iron-responsive element-binding protein 2 chr15 GO:0002376 Not Cancer Driver No 126 0.131 107 13 0.121 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0002376 Compendium Yes 49 0.151 228 31 0.136 2
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 GO:0002376 Not Cancer Driver No 85 0.244 288 73 0.253 0
IRF2BP2 IRF2BP2 Q7Z5L9 Interferon regulatory factor 2-binding protein 2 chr1 GO:0002376 Not Cancer Driver No 42 0.072 451 26 0.058 1
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0002376 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0002376 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF5_ENST00000402030 IRF5 Q13568 Interferon regulatory factor 5 chr7 GO:0002376 Not Cancer Driver No 93 0.187 237 64 0.27 0
IRF6 IRF6 O14896 Interferon regulatory factor 6 chr1 GO:0002376 Not Cancer Driver No 97 0.208 173 36 0.208 45
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0002376 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0002376 Not Cancer Driver No 80 0.188 77 20 0.26 2
IRF9 IRF9 Q00978 Interferon regulatory factor 9 chr14 GO:0002376 Not Cancer Driver No 48 0.122 204 15 0.074 0
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:0002376 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0002376 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0002376 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGA9 ITGA9 Q13797 Integrin alpha-9 chr3 GO:0002376 Not Cancer Driver No 137 0.132 70 14 0.2 0
ITGAL ITGAL P20701 Integrin alpha-L chr16 GO:0002376 Not Cancer Driver No 196 0.168 144 25 0.174 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0002376 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0002376 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0002376 Not Cancer Driver No 120 0.152 26 4 0.154 3
ITGB7 ITGB7 P26010 Integrin beta-7 chr12 GO:0002376 Not Cancer Driver No 80 0.1 125 3 0.024 0
ITGB8 ITGB8 P26012 Integrin beta-8 chr7 GO:0002376 Not Cancer Driver No 126 0.164 26 3 0.115 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0002376 Census Yes 139 0.224 43 10 0.233 1
ITM2A ITM2A O43736 Integral membrane protein 2A chrX GO:0002376 Not Cancer Driver No 75 0.285 26 9 0.346 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0002376 Not Cancer Driver No 148 0.156 719 119 0.166 0
JAG2 JAG2 Q9Y219 Protein jagged-2 chr14 GO:0002376 Not Cancer Driver No 126 0.102 158 24 0.152 0
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 GO:0002376 Not Cancer Driver No 21 0.115 12 2 0.167 5
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0002376 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0002376 Census, Compendium Yes 167 0.149 63 10 0.159 7
JAM2_ENST00000480456 JAM2 P57087 Junctional adhesion molecule B chr21 GO:0002376 Not Cancer Driver No 63 0.211 64 16 0.25 2
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0002376 Not Cancer Driver No 50 0.161 62 11 0.177 2
JAML JAML Q86YT9 Junctional adhesion molecule-like chr11 GO:0002376 Not Cancer Driver No 72 0.183 68 11 0.162 0
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0002376 Not Cancer Driver No 51 0.127 133 21 0.158 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0002376 Census Yes 35 0.106 281 25 0.089 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0002376 Not Cancer Driver No 88 0.147 160 15 0.094 12
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0002376 Census Yes 97 0.159 327 47 0.144 0
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0002376 Not Cancer Driver No 60 0.141 31 6 0.194 3
KDM5D KDM5D Q9BY66 Lysine-specific demethylase 5D chrY GO:0002376 Not Cancer Driver No 50 0.032 406 11 0.027 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0002376 Census, Compendium Yes 122 0.127 586 67 0.114 0
KIR3DL1 KIR3DL1 P43629 Killer cell immunoglobulin-like receptor 3DL1 chr19 GO:0002376 Not Cancer Driver No 124 0.279 184 48 0.261 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0002376 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLHL6 KLHL6 Q8WZ60 Kelch-like protein 6 chr3 GO:0002376 Compendium Yes 149 0.24 25 7 0.28 0
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0002376 Not Cancer Driver No 49 0.21 49 10 0.204 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0002376 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRC3_ENST00000396439 KLRC3 Q07444 NKG2-E type II integral membrane protein chr12 GO:0002376 Not Cancer Driver No 37 0.154 43 4 0.093 0
KLRC4 KLRC4 O43908 NKG2-F type II integral membrane protein chr12 GO:0002376 Not Cancer Driver No 36 0.228 45 7 0.156 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0002376 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRF2 KLRF2 D3W0D1 Killer cell lectin-like receptor subfamily F member 2 chr12 GO:0002376 Not Cancer Driver No 1 0.005 0 0 0.0 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0002376 Not Cancer Driver No 38 0.176 0 0 0.0 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 GO:0002376 Not Cancer Driver No 233 0.125 1613 198 0.123 4
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0002376 Not Cancer Driver No 133 0.207 426 98 0.23 20
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0002376 Not Cancer Driver No 47 0.09 208 11 0.053 0
LAT2 LAT2 Q9GZY6 Linker for activation of T-cells family member 2 chr7 GO:0002376 Not Cancer Driver No 39 0.16 176 29 0.165 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0002376 Not Cancer Driver No 37 0.141 213 29 0.136 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0002376 Not Cancer Driver No 84 0.175 6 0 0.0 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0002376 Census Yes 86 0.169 94 13 0.138 1
LCP2 LCP2 Q13094 Lymphocyte cytosolic protein 2 chr5 GO:0002376 Not Cancer Driver No 107 0.201 390 80 0.205 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0002376 Census Yes 64 0.16 370 57 0.154 0
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0002376 Not Cancer Driver No 37 0.098 65 1 0.015 1
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0002376 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS2 LGALS2 P05162 Galectin-2 chr22 GO:0002376 Not Cancer Driver No 19 0.144 36 4 0.111 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0002376 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0002376 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0002376 Not Cancer Driver No 57 0.132 112 19 0.17 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0002376 Not Cancer Driver No 134 0.147 63 10 0.159 2
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0002376 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0002376 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0002376 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0002376 Not Cancer Driver No 110 0.17 170 30 0.176 0
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 GO:0002376 Not Cancer Driver No 115 0.112 103 8 0.078 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0002376 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0002376 Not Cancer Driver No 105 0.13 32 3 0.094 0
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 GO:0002376 Not Cancer Driver No 44 0.101 200 21 0.105 0
LTF LTF P02788 Lactotransferrin chr3 GO:0002376 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0002376 Census Yes 95 0.186 84 12 0.143 0
LYST LYST Q99698 Lysosomal-trafficking regulator chr1 GO:0002376 Not Cancer Driver No 465 0.122 608 87 0.143 4
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:0002376 Census Yes 35 0.108 301 34 0.113 10
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0002376 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0002376 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP3K8_ENST00000542547 MAP3K8 P41279 Mitogen-activated protein kinase kinase kinase 8 chr10 GO:0002376 Not Cancer Driver No 58 0.124 109 10 0.092 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0002376 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARCH1 MARCHF1 Q8TCQ1 E3 ubiquitin-protein ligase MARCHF1 chr4 GO:0002376 Not Cancer Driver No 65 0.225 74 16 0.216 0
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0002376 Not Cancer Driver No 33 0.134 23 5 0.217 0
MARCH8_ENST00000319836 MARCHF8 Q5T0T0 E3 ubiquitin-protein ligase MARCHF8 chr10 GO:0002376 Not Cancer Driver No 31 0.107 71 8 0.113 0
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 GO:0002376 Not Cancer Driver No 142 0.203 72 14 0.194 0
MASP2 MASP2 O00187 Mannan-binding lectin serine protease 2 chr1 GO:0002376 Not Cancer Driver No 99 0.144 58 11 0.19 2
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0002376 Not Cancer Driver No 63 0.254 122 32 0.262 0
MCM3AP_ENST00000291688 MCM3AP O60318 Germinal-center associated nuclear protein chr21 GO:0002376 Compendium Yes 228 0.115 762 93 0.122 0
MCOLN2 MCOLN2 Q8IZK6 Mucolipin-2 chr1 GO:0002376 Not Cancer Driver No 93 0.164 0 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0002376 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0002376 Not Cancer Driver No 92 0.195 408 81 0.199 0
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0002376 Not Cancer Driver No 175 0.175 159 31 0.195 3
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0002376 Not Cancer Driver No 35 0.137 0 0 0.0 0
MFNG MFNG O00587 Beta-1,3-N-acetylglucosaminyltransferase manic fringe chr22 GO:0002376 Not Cancer Driver No 37 0.115 29 4 0.138 0
MFSD6_ENST00000281416 MFSD6 Q6ZSS7 Major facilitator superfamily domain-containing protein 6 chr2 GO:0002376 Not Cancer Driver No 82 0.104 252 26 0.103 0
MICB MICB Q29980 MHC class I polypeptide-related sequence B chr6 GO:0002376 Not Cancer Driver No 56 0.146 175 22 0.126 0
MILR1 MILR1 Q7Z6M3 Allergin-1 chr17 GO:0002376 Not Cancer Driver No 11 0.032 60 4 0.067 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0002376 Census Yes 92 0.122 208 22 0.106 85
MPL MPL P40238 Thrombopoietin receptor chr1 GO:0002376 Census Yes 77 0.121 129 19 0.147 14
MPO MPO P05164 Myeloperoxidase chr17 GO:0002376 Not Cancer Driver No 149 0.2 52 12 0.231 3
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0002376 Not Cancer Driver No 60 0.176 33 7 0.212 0
MRGPRX2 MRGPRX2 Q96LB1 Mas-related G-protein coupled receptor member X2 chr11 GO:0002376 Not Cancer Driver No 86 0.261 11 2 0.182 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0002376 Census Yes 92 0.099 37 4 0.108 70
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0002376 Census Yes 154 0.113 386 41 0.106 6
MSMP MSMP Q1L6U9 Prostate-associated microseminoprotein chr9 GO:0002376 Not Cancer Driver No 15 0.108 27 0 0.0 0
MSN MSN P26038 Moesin chrX GO:0002376 Census, Compendium Yes 108 0.187 286 56 0.196 1
MT1G MT1G P13640 Metallothionein-1G chr16 GO:0002376 Not Cancer Driver No 9 0.145 0 0 0.0 0
MX1_ENST00000398598 MX1 P20591 Interferon-induced GTP-binding protein Mx1 chr21 GO:0002376 Not Cancer Driver No 88 0.133 74 10 0.135 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0002376 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYO1G MYO1G B0I1T2 Unconventional myosin-Ig chr7 GO:0002376 Not Cancer Driver No 125 0.123 117 12 0.103 0
MYSM1 MYSM1 Q5VVJ2 Deubiquitinase MYSM1 chr1 GO:0002376 Not Cancer Driver No 78 0.094 345 26 0.075 1
NBN NBN O60934 Nibrin chr8 GO:0002376 Census Yes 90 0.119 417 54 0.129 1
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 GO:0002376 Not Cancer Driver No 67 0.111 335 39 0.116 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0002376 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCR1 NCR1 O76036 Natural cytotoxicity triggering receptor 1 chr19 GO:0002376 Not Cancer Driver No 81 0.266 27 8 0.296 0
NCR3 NCR3 O14931 Natural cytotoxicity triggering receptor 3 chr6 GO:0002376 Not Cancer Driver No 26 0.129 31 2 0.065 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0002376 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 GO:0002376 Census Yes 66 0.168 140 22 0.157 0
NFIL3 NFIL3 Q16649 Nuclear factor interleukin-3-regulated protein chr9 GO:0002376 Not Cancer Driver No 57 0.123 333 41 0.123 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 GO:0002376 Census, Compendium Yes 86 0.096 510 46 0.09 0
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0002376 Not Cancer Driver No 35 0.117 83 8 0.096 2
NINJ1 NINJ1 Q92982 Ninjurin-1 chr9 GO:0002376 Not Cancer Driver No 17 0.112 29 0 0.0 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0002376 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKG7 NKG7 Q16617 Protein NKG7 chr19 GO:0002376 Not Cancer Driver No 34 0.206 0 0 0.0 0
NKX2-3 NKX2-3 Q8TAU0 Homeobox protein Nkx-2.3 chr10 GO:0002376 Not Cancer Driver No 31 0.085 212 27 0.127 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0002376 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0002376 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0002376 Not Cancer Driver No 106 0.119 203 28 0.138 0
NMI NMI Q13287 N-myc-interactor chr2 GO:0002376 Not Cancer Driver No 34 0.111 104 12 0.115 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0002376 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0002376 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0002376 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0002376 Census, Compendium Yes 282 0.114 630 77 0.122 1
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0002376 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0002376 Census Yes 83 0.133 298 37 0.124 0
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 GO:0002376 Not Cancer Driver No 75 0.129 38 4 0.105 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0002376 Not Cancer Driver No 67 0.168 71 12 0.169 0
OLR1 OLR1 P78380 Oxidized low-density lipoprotein receptor 1 chr12 GO:0002376 Not Cancer Driver No 38 0.139 75 8 0.107 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0002376 Not Cancer Driver No 107 0.268 58 27 0.466 0
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 GO:0002376 Not Cancer Driver No 124 0.147 537 87 0.162 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0002376 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0002376 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0002376 Not Cancer Driver No 57 0.167 21 2 0.095 3
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0002376 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0002376 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0002376 Not Cancer Driver No 127 0.227 286 64 0.224 2
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0002376 Census Yes 82 0.191 290 57 0.197 0
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0002376 Census, Compendium Yes 33 0.121 41 13 0.317 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0002376 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0002376 Census Yes 37 0.154 99 22 0.222 2
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 GO:0002376 Not Cancer Driver No 2 0.003 153 2 0.013 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0002376 Not Cancer Driver No 13 0.129 0 0 0.0 0
PF4V1 PF4V1 P10720 Platelet factor 4 variant chr4 GO:0002376 Not Cancer Driver No 18 0.173 6 2 0.333 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0002376 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0002376 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0002376 Not Cancer Driver No 83 0.11 419 45 0.107 2
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0002376 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0002376 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0002376 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0002376 Not Cancer Driver No 278 0.133 848 101 0.119 1
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0002376 Not Cancer Driver No 98 0.147 360 60 0.167 1
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0002376 Not Cancer Driver No 120 0.127 459 54 0.118 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0002376 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0002376 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0002376 Not Cancer Driver No 27 0.186 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0002376 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0002376 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0002376 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0002376 Not Cancer Driver No 185 0.164 274 31 0.113 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 GO:0002376 Not Cancer Driver No 107 0.115 97 8 0.082 0
PLD3_ENST00000409735 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 GO:0002376 Not Cancer Driver No 70 0.143 62 7 0.113 0
PLEC PLEC Q15149 Plectin chr8 GO:0002376 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PLEKHM2 PLEKHM2 Q8IWE5 Pleckstrin homology domain-containing family M member 2 chr1 GO:0002376 Not Cancer Driver No 96 0.094 392 35 0.089 0
PLG PLG P00747 Plasminogen chr6 GO:0002376 Not Cancer Driver No 242 0.299 230 64 0.278 9
PLPP4 PLPP4 Q5VZY2 Phospholipid phosphatase 4 chr10 GO:0002376 Not Cancer Driver No 59 0.218 14 1 0.071 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0002376 Not Cancer Driver No 2 0.037 23 1 0.043 0
PMS2 PMS2 P54278 Mismatch repair endonuclease PMS2 chr7 GO:0002376 Census, Compendium Yes 117 0.136 331 44 0.133 9
PNMA1 PNMA1 Q8ND90 Paraneoplastic antigen Ma1 chr14 GO:0002376 Not Cancer Driver No 48 0.136 56 9 0.161 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0002376 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLL_ENST00000370169 POLL Q9UGP5 DNA polymerase lambda chr10 GO:0002376 Not Cancer Driver No 69 0.12 215 16 0.074 0
POLQ POLQ O75417 DNA polymerase theta chr3 GO:0002376 Census, Compendium Yes 364 0.141 949 135 0.142 0
POU2AF1 POU2AF1 Q16633 POU domain class 2-associating factor 1 chr11 GO:0002376 Census Yes 59 0.23 181 45 0.249 0
PPBP PPBP P02775 Platelet basic protein chr4 GO:0002376 Not Cancer Driver No 30 0.234 21 8 0.381 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0002376 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 GO:0002376 Not Cancer Driver No 28 0.13 16 1 0.062 1
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0002376 Not Cancer Driver No 44 0.097 30 3 0.1 0
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0002376 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 GO:0002376 Not Cancer Driver No 22 0.111 40 5 0.125 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0002376 Not Cancer Driver No 24 0.121 30 4 0.133 0
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0002376 Not Cancer Driver No 297 0.179 307 55 0.179 0
PRF1_ENST00000373209 PRF1 P14222 Perforin-1 chr10 GO:0002376 Census, Compendium Yes 122 0.22 145 36 0.248 8
PRG3 PRG3 Q9Y2Y8 Proteoglycan 3 chr11 GO:0002376 Not Cancer Driver No 40 0.178 60 12 0.2 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0002376 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0002376 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0002376 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0002376 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0002376 Not Cancer Driver No 10 0.036 199 6 0.03 0
PRTN3 PRTN3 P24158 Myeloblastin chr19 GO:0002376 Not Cancer Driver No 20 0.078 46 1 0.022 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0002376 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSG9 PSG9 Q00887 Pregnancy-specific beta-1-glycoprotein 9 chr19 GO:0002376 Not Cancer Driver No 125 0.293 40 8 0.2 0
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 GO:0002376 Not Cancer Driver No 48 0.183 51 9 0.176 0
PSMB11 PSMB11 A5LHX3 Proteasome subunit beta type-11 chr14 GO:0002376 Not Cancer Driver No 62 0.207 71 11 0.155 0
PSMB9 PSMB9 P28065 Proteasome subunit beta type-9 chr6 GO:0002376 Not Cancer Driver No 21 0.096 17 1 0.059 1
PSME1_ENST00000206451 PSME1 Q06323 Proteasome activator complex subunit 1 chr14 GO:0002376 Not Cancer Driver No 20 0.08 80 8 0.1 0
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0002376 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGDS PTGDS P41222 Prostaglandin-H2 D-isomerase chr9 GO:0002376 Not Cancer Driver No 31 0.163 13 3 0.231 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0002376 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0002376 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0002376 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTMS_ENST00000309083 PTMS P20962 Parathymosin chr12 GO:0002376 Not Cancer Driver No 10 0.098 102 10 0.098 0
PTN PTN P21246 Pleiotrophin chr7 GO:0002376 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0002376 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0002376 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0002376 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0002376 Not Cancer Driver No 204 0.168 137 34 0.248 0
PTX3 PTX3 P26022 Pentraxin-related protein PTX3 chr3 GO:0002376 Not Cancer Driver No 39 0.102 74 2 0.027 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0002376 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0002376 Not Cancer Driver No 25 0.113 15 4 0.267 3
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 GO:0002376 Not Cancer Driver No 37 0.157 1 0 0.0 1
RAET1E RAET1E Q8TD07 Retinoic acid early transcript 1E chr6 GO:0002376 Not Cancer Driver No 40 0.152 0 0 0.0 0
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0002376 Not Cancer Driver No 41 0.123 62 10 0.161 0
RAET1L_ENST00000286380 RAET1L Q5VY80 UL16-binding protein 6 chr6 GO:0002376 Not Cancer Driver No 30 0.122 30 2 0.067 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0002376 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0002376 Not Cancer Driver No 118 0.224 85 23 0.271 6
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0002376 Not Cancer Driver No 16 0.098 14 2 0.143 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0002376 Not Cancer Driver No 96 0.12 191 12 0.063 1
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0002376 Not Cancer Driver No 49 0.098 151 19 0.126 2
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0002376 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0002376 Not Cancer Driver No 128 0.107 703 81 0.115 0
RELB RELB Q01201 Transcription factor RelB chr19 GO:0002376 Not Cancer Driver No 65 0.112 348 39 0.112 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0002376 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFTN1 RFTN1 Q14699 Raftlin chr3 GO:0002376 Not Cancer Driver No 87 0.151 319 44 0.138 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0002376 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 GO:0002376 Census Yes 41 0.215 12 3 0.25 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0002376 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNASE2 RNASE2 P10153 Non-secretory ribonuclease chr14 GO:0002376 Not Cancer Driver No 30 0.186 20 4 0.2 0
RNASE3 RNASE3 P12724 Eosinophil cationic protein chr14 GO:0002376 Not Cancer Driver No 37 0.231 8 0 0.0 0
RNASE8 RNASE8 Q8TDE3 Ribonuclease 8 chr14 GO:0002376 Not Cancer Driver No 18 0.117 17 2 0.118 0
RNF135 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0002376 Not Cancer Driver No 40 0.093 139 11 0.079 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0002376 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 GO:0002376 Not Cancer Driver No 58 0.079 344 24 0.07 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0002376 Not Cancer Driver No 56 0.115 226 29 0.128 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0002376 Not Cancer Driver No 203 0.215 299 71 0.237 5
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0002376 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0002376 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPL39 RPL39 P62891 60S ribosomal protein L39 chrX GO:0002376 Not Cancer Driver No 9 0.176 51 9 0.176 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0002376 Not Cancer Driver No 15 0.103 61 3 0.049 23
RPS24_ENST00000613865 RPS24 P62847 40S ribosomal protein S24 chr10 GO:0002376 Not Cancer Driver No 13 0.098 88 10 0.114 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0002376 Not Cancer Driver No 38 0.153 150 25 0.167 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0002376 Not Cancer Driver No 68 0.188 22 1 0.045 0
RUBCN RUBCN Q92622 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 GO:0002376 Not Cancer Driver No 147 0.151 403 57 0.141 0
S100A12 S100A12 P80511 Protein S100-A12 chr1 GO:0002376 Not Cancer Driver No 18 0.196 1 0 0.0 0
S100A13_ENST00000392622 S100A13 Q99584 Protein S100-A13 chr1 GO:0002376 Not Cancer Driver No 12 0.122 6 0 0.0 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0002376 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0002376 Not Cancer Driver No 18 0.158 76 7 0.092 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0002376 Not Cancer Driver No 86 0.225 29 6 0.207 0
SAA1 SAA1 P0DJI8 Serum amyloid A-1 protein chr11 GO:0002376 Not Cancer Driver No 23 0.189 25 5 0.2 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0002376 Not Cancer Driver No 104 0.166 91 14 0.154 13
SAR1B SAR1B Q9Y6B6 GTP-binding protein SAR1b chr5 GO:0002376 Not Cancer Driver No 17 0.086 4 0 0.0 5
SBNO2 SBNO2 Q9Y2G9 Protein strawberry notch homolog 2 chr19 GO:0002376 Not Cancer Driver No 108 0.079 456 29 0.064 0
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0002376 Not Cancer Driver No 116 0.188 531 103 0.194 0
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0002376 Not Cancer Driver No 90 0.141 62 4 0.065 13
SELE SELE P16581 E-selectin chr1 GO:0002376 Not Cancer Driver No 137 0.225 12 0 0.0 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0002376 Not Cancer Driver No 10 0.106 47 6 0.128 0
SELPLG_ENST00000550948 SELPLG Q14242 P-selectin glycoprotein ligand 1 chr12 GO:0002376 Not Cancer Driver No 68 0.165 297 48 0.162 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0002376 Not Cancer Driver No 123 0.162 122 26 0.213 4
SENP7 SENP7 Q9BQF6 Sentrin-specific protease 7 chr3 GO:0002376 Not Cancer Driver No 149 0.142 523 73 0.14 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0002376 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 GO:0002376 Not Cancer Driver No 74 0.148 113 13 0.115 40
SFTPA1_ENST00000398636 SFTPA1 Q8IWL2 Pulmonary surfactant-associated protein A1 chr10 GO:0002376 Not Cancer Driver No 41 0.165 171 33 0.193 3
SFTPD SFTPD P35247 Pulmonary surfactant-associated protein D chr10 GO:0002376 Not Cancer Driver No 66 0.176 274 53 0.193 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0002376 Census, Compendium Yes 48 0.083 333 19 0.057 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0002376 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0002376 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIT1 SIT1 Q9Y3P8 Signaling threshold-regulating transmembrane adapter 1 chr9 GO:0002376 Not Cancer Driver No 21 0.107 122 9 0.074 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:0002376 Not Cancer Driver No 77 0.113 356 32 0.09 0
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:0002376 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0002376 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF7 SLAMF7 Q9NQ25 SLAM family member 7 chr1 GO:0002376 Not Cancer Driver No 66 0.197 53 14 0.264 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0002376 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLAMF9 SLAMF9 Q96A28 SLAM family member 9 chr1 GO:0002376 Not Cancer Driver No 67 0.232 28 7 0.25 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0002376 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0002376 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 GO:0002376 Not Cancer Driver No 66 0.114 23 4 0.174 0
SLC39A3 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 GO:0002376 Not Cancer Driver No 41 0.131 0 0 0.0 0
SLC40A1 SLC40A1 Q9NP59 Solute carrier family 40 member 1 chr2 GO:0002376 Not Cancer Driver No 63 0.11 48 3 0.062 12
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0002376 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:0002376 Not Cancer Driver No 177 0.196 34 8 0.235 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0002376 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0002376 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0002376 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:0002376 Not Cancer Driver No 173 0.13 362 54 0.149 2
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0002376 Not Cancer Driver No 85 0.137 564 77 0.137 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0002376 Not Cancer Driver No 66 0.085 587 37 0.063 0
SPACA3 SPACA3 Q8IXA5 Sperm acrosome membrane-associated protein 3 chr17 GO:0002376 Not Cancer Driver No 52 0.242 0 0 0.0 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0002376 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPNS2 SPNS2 Q8IVW8 Sphingosine-1-phosphate transporter SPNS2 chr17 GO:0002376 Not Cancer Driver No 54 0.098 82 0 0.0 0
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 GO:0002376 Not Cancer Driver No 36 0.109 73 4 0.055 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 GO:0002376 Not Cancer Driver No 1046 0.432 707 294 0.416 21
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0002376 Not Cancer Driver No 54 0.123 267 32 0.12 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0002376 Census Yes 53 0.099 130 11 0.085 1
SRF SRF P11831 Serum response factor chr6 GO:0002376 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRP54 SRP54 P61011 Signal recognition particle 54 kDa protein chr14 GO:0002376 Not Cancer Driver No 53 0.105 115 13 0.113 7
ST3GAL1_ENST00000522652 ST3GAL1 Q11201 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 chr8 GO:0002376 Not Cancer Driver No 51 0.15 6 0 0.0 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0002376 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0002376 Census, Compendium Yes 93 0.118 144 19 0.132 5
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0002376 Census, Compendium Yes 75 0.173 135 14 0.104 9
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0002376 Not Cancer Driver No 40 0.112 117 9 0.077 0
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0002376 Not Cancer Driver No 77 0.13 80 13 0.163 5
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0002376 Not Cancer Driver No 59 0.1 64 9 0.141 0
SUCNR1 SUCNR1 Q9BXA5 Succinate receptor 1 chr3 GO:0002376 Not Cancer Driver No 51 0.153 0 0 0.0 0
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 GO:0002376 Not Cancer Driver No 85 0.173 134 27 0.201 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0002376 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0002376 Census Yes 96 0.151 131 27 0.206 5
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0002376 Not Cancer Driver No 63 0.102 284 32 0.113 0
TAP2 TAP2 Q03519 Antigen peptide transporter 2 chr6 GO:0002376 Not Cancer Driver No 71 0.103 20 1 0.05 0
TAPBP_ENST00000434618 TAPBP O15533 Tapasin chr6 GO:0002376 Not Cancer Driver No 58 0.129 168 26 0.155 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0002376 Not Cancer Driver No 101 0.139 42 5 0.119 12
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0002376 Census Yes 52 0.08 649 52 0.08 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0002376 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0002376 Compendium Yes 68 0.082 102 6 0.059 5
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0002376 Not Cancer Driver No 127 0.244 284 84 0.296 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0002376 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0002376 Census, Compendium Yes 106 0.187 60 16 0.267 25
THEMIS_ENST00000368250 THEMIS Q8N1K5 Protein THEMIS chr6 GO:0002376 Not Cancer Driver No 208 0.324 111 34 0.306 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0002376 Not Cancer Driver No 92 0.129 443 66 0.149 1
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0002376 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0002376 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0002376 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0002376 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0002376 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR8_ENST00000218032 TLR8 Q9NR97 Toll-like receptor 8 chrX GO:0002376 Not Cancer Driver No 180 0.173 30 7 0.233 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 GO:0002376 Not Cancer Driver No 26 0.099 9 1 0.111 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 GO:0002376 Not Cancer Driver No 39 0.173 27 3 0.111 2
TMIGD2 TMIGD2 Q96BF3 Transmembrane and immunoglobulin domain-containing protein 2 chr19 GO:0002376 Not Cancer Driver No 57 0.202 120 32 0.267 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0002376 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0002376 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0002376 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFRSF13B TNFRSF13B O14836 Tumor necrosis factor receptor superfamily member 13B chr17 GO:0002376 Not Cancer Driver No 60 0.205 108 25 0.231 0
TNFRSF13C TNFRSF13C Q96RJ3 Tumor necrosis factor receptor superfamily member 13C chr22 GO:0002376 Not Cancer Driver No 17 0.092 128 15 0.117 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0002376 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF17 TNFRSF17 Q02223 Tumor necrosis factor receptor superfamily member 17 chr16 GO:0002376 Census Yes 28 0.152 1 0 0.0 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0002376 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 GO:0002376 Not Cancer Driver No 41 0.144 91 15 0.165 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0002376 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0002376 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF8 TNFSF8 P32971 Tumor necrosis factor ligand superfamily member 8 chr9 GO:0002376 Not Cancer Driver No 34 0.145 30 2 0.067 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0002376 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0002376 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0002376 Not Cancer Driver No 59 0.103 410 39 0.095 2
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0002376 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM1 TREM1 Q9NP99 Triggering receptor expressed on myeloid cells 1 chr6 GO:0002376 Not Cancer Driver No 45 0.192 63 7 0.111 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0002376 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0002376 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 GO:0002376 Not Cancer Driver No 134 0.245 276 78 0.283 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0002376 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0002376 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0002376 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0002376 Census, Compendium Yes 135 0.116 732 78 0.107 11
TTLL1 TTLL1 O95922 Polyglutamylase complex subunit TTLL1 chr22 GO:0002376 Not Cancer Driver No 69 0.163 48 9 0.188 0
TUBB TUBB P07437 Tubulin beta chain chr6 GO:0002376 Not Cancer Driver No 40 0.09 63 11 0.175 5
TUBB4B TUBB4B P68371 Tubulin beta-4B chain chr9 GO:0002376 Not Cancer Driver No 52 0.117 65 11 0.169 2
TUSC2 TUSC2 O75896 Tumor suppressor candidate 2 chr3 GO:0002376 Not Cancer Driver No 10 0.091 31 3 0.097 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0002376 Not Cancer Driver No 119 0.134 197 17 0.086 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0002376 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBD UBD O15205 Ubiquitin D chr6 GO:0002376 Not Cancer Driver No 31 0.188 8 1 0.125 0
ULBP1 ULBP1 Q9BZM6 UL16-binding protein 1 chr6 GO:0002376 Not Cancer Driver No 48 0.197 24 4 0.167 0
ULBP2 ULBP2 Q9BZM5 UL16-binding protein 2 chr6 GO:0002376 Not Cancer Driver No 33 0.134 25 2 0.08 0
ULBP3 ULBP3 Q9BZM4 UL16-binding protein 3 chr6 GO:0002376 Not Cancer Driver No 34 0.139 14 1 0.071 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0002376 Not Cancer Driver No 120 0.11 248 30 0.121 0
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0002376 Not Cancer Driver No 34 0.109 96 13 0.135 1
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 GO:0002376 Not Cancer Driver No 7 0.06 47 4 0.085 3
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0002376 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0002376 Not Cancer Driver No 9 0.09 27 0 0.0 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0002376 Census, Compendium Yes 165 0.195 113 19 0.168 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0002376 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0002376 Not Cancer Driver No 153 0.181 102 18 0.176 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0002376 Not Cancer Driver No 73 0.183 70 13 0.186 0
VSTM1 VSTM1 Q6UX27 V-set and transmembrane domain-containing protein 1 chr19 GO:0002376 Not Cancer Driver No 72 0.305 126 40 0.317 0
WDFY4 WDFY4 Q6ZS81 WD repeat- and FYVE domain-containing protein 4 chr10 GO:0002376 Not Cancer Driver No 217 0.068 475 36 0.076 0
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0002376 Not Cancer Driver No 66 0.109 30 7 0.233 2
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0002376 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0002376 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0002376 Not Cancer Driver No 30 0.085 39 4 0.103 4
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0002376 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0002376 Not Cancer Driver No 20 0.175 35 5 0.143 0
XG_ENST00000381174 XG P55808 Glycoprotein Xg chrX GO:0002376 Not Cancer Driver No 27 0.15 140 23 0.164 0
XKR8 XKR8 Q9H6D3 XK-related protein 8 chr1 GO:0002376 Not Cancer Driver No 34 0.086 4 0 0.0 0
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 GO:0002376 Not Cancer Driver No 47 0.14 171 31 0.181 3
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0002376 Not Cancer Driver No 65 0.12 62 10 0.161 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:0002376 Not Cancer Driver No 87 0.156 369 46 0.125 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0002376 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0002376 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0002376 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0002376 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZDHHC1 ZDHHC1 Q8WTX9 Palmitoyltransferase ZDHHC1 chr16 GO:0002376 Not Cancer Driver No 46 0.095 167 11 0.066 0
ZDHHC11 ZDHHC11 Q9H8X9 Palmitoyltransferase ZDHHC11 chr5 GO:0002376 Not Cancer Driver No 68 0.165 76 24 0.316 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0002376 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0002376 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0002376 Not Cancer Driver No 55 0.13 56 11 0.196 1