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Total number of protein in "GO:0002250" GO term:  234

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0002250 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADGRE1 ADGRE1 Q14246 Adhesion G protein-coupled receptor E1 chr19 GO:0002250 Not Cancer Driver No 204 0.23 15 7 0.467 0
AIRE AIRE O43918 Autoimmune regulator chr21 GO:0002250 Not Cancer Driver No 71 0.13 338 48 0.142 19
ALCAM ALCAM Q13740 CD166 antigen chr3 GO:0002250 Not Cancer Driver No 89 0.153 96 19 0.198 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0002250 Not Cancer Driver No 59 0.171 61 12 0.197 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0002250 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0002250 Not Cancer Driver No 25 0.071 58 3 0.052 0
BACH2_ENST00000537989 BACH2 Q9BYV9 Transcription regulator protein BACH2 chr6 GO:0002250 Not Cancer Driver No 178 0.212 503 88 0.175 1
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0002250 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0002250 Census Yes 44 0.097 259 23 0.089 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0002250 Census, Compendium Yes 134 0.19 328 67 0.204 0
BMX_ENST00000342014 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX GO:0002250 Not Cancer Driver No 106 0.157 172 27 0.157 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0002250 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTLA BTLA Q7Z6A9 B- and T-lymphocyte attenuator chr3 GO:0002250 Not Cancer Driver No 31 0.107 57 5 0.088 0
BTN3A1 BTN3A1 O00481 Butyrophilin subfamily 3 member A1 chr6 GO:0002250 Not Cancer Driver No 77 0.15 72 18 0.25 0
BTNL8 BTNL8 Q6UX41 Butyrophilin-like protein 8 chr5 GO:0002250 Not Cancer Driver No 132 0.264 84 22 0.262 0
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0002250 Not Cancer Driver No 16 0.06 84 3 0.036 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0002250 Not Cancer Driver No 106 0.24 103 28 0.272 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0002250 Not Cancer Driver No 101 0.214 127 30 0.236 0
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0002250 Not Cancer Driver No 72 0.134 225 35 0.156 11
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0002250 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0002250 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD1A CD1A P06126 T-cell surface glycoprotein CD1a chr1 GO:0002250 Not Cancer Driver No 105 0.321 18 6 0.333 0
CD1B CD1B P29016 T-cell surface glycoprotein CD1b chr1 GO:0002250 Not Cancer Driver No 97 0.291 7 0 0.0 0
CD1C CD1C P29017 T-cell surface glycoprotein CD1c chr1 GO:0002250 Not Cancer Driver No 127 0.381 1 0 0.0 0
CD1E CD1E P15812 T-cell surface glycoprotein CD1e, membrane-associated chr1 GO:0002250 Not Cancer Driver No 158 0.407 21 11 0.524 0
CD209 CD209 Q9NNX6 CD209 antigen chr19 GO:0002250 Census Yes 116 0.287 42 8 0.19 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0002250 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0002250 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0002250 Census Yes 29 0.1 54 9 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0002250 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0002250 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0002250 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0002250 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD7 CD7 P09564 T-cell antigen CD7 chr17 GO:0002250 Not Cancer Driver No 36 0.15 74 7 0.095 0
CD70_ENST00000245903 CD70 P32970 CD70 antigen chr19 GO:0002250 Not Cancer Driver No 33 0.171 11 2 0.182 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0002250 Census Yes 31 0.105 185 20 0.108 0
CD79A CD79A P11912 B-cell antigen receptor complex-associated protein alpha chain chr19 GO:0002250 Census Yes 32 0.142 28 3 0.107 0
CD79B_ENST00000006750 CD79B P40259 B-cell antigen receptor complex-associated protein beta chain chr17 GO:0002250 Census, Compendium Yes 25 0.109 43 10 0.233 1
CD81 CD81 P60033 CD81 antigen chr11 GO:0002250 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0002250 Not Cancer Driver No 82 0.238 52 11 0.212 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0002250 Not Cancer Driver No 90 0.274 56 18 0.321 0
CD8B2 CD8B2 A6NJW9 T-cell surface glycoprotein CD8 beta-2 chain chr2 GO:0002250 Not Cancer Driver No 1 0.005 10 0 0.0 0
CLEC10A CLEC10A Q8IUN9 C-type lectin domain family 10 member A chr17 GO:0002250 Not Cancer Driver No 47 0.149 43 7 0.163 0
CLEC4A CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 GO:0002250 Not Cancer Driver No 35 0.148 22 4 0.182 0
CLEC4C_ENST00000360345 CLEC4C Q8WTT0 C-type lectin domain family 4 member C chr12 GO:0002250 Not Cancer Driver No 58 0.272 5 1 0.2 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0002250 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC4M CLEC4M Q9H2X3 C-type lectin domain family 4 member M chr19 GO:0002250 Not Cancer Driver No 85 0.213 40 13 0.325 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0002250 Not Cancer Driver No 41 0.196 7 0 0.0 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0002250 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 GO:0002250 Not Cancer Driver No 204 0.227 541 120 0.222 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0002250 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0002250 Not Cancer Driver No 37 0.166 3 0 0.0 1
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:0002250 Not Cancer Driver No 64 0.138 19 5 0.263 29
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0002250 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSL CTSL P07711 Procathepsin L chr9 GO:0002250 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSS CTSS P25774 Cathepsin S chr1 GO:0002250 Not Cancer Driver No 54 0.163 0 0 0.0 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0002250 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0002250 Not Cancer Driver No 11 0.101 0 0 0.0 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0002250 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:0002250 Not Cancer Driver No 76 0.11 277 26 0.094 3
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0002250 Not Cancer Driver No 32 0.14 10 1 0.1 0
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0002250 Not Cancer Driver No 156 0.095 494 44 0.089 2
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0002250 Not Cancer Driver No 24 0.144 0 0 0.0 2
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0002250 Not Cancer Driver No 82 0.12 436 50 0.115 0
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 GO:0002250 Not Cancer Driver No 78 0.083 70 2 0.029 0
ERAP2 ERAP2 Q6P179 Endoplasmic reticulum aminopeptidase 2 chr5 GO:0002250 Not Cancer Driver No 97 0.101 23 4 0.174 0
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0002250 Not Cancer Driver No 123 0.145 472 76 0.161 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 GO:0002250 Not Cancer Driver No 133 0.112 440 48 0.109 1
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0002250 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0002250 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCGR1B FCGR1BP Q92637 Putative high affinity immunoglobulin gamma Fc receptor IB chr1 GO:0002250 Not Cancer Driver No 31 0.111 37 6 0.162 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0002250 Census Yes 51 0.165 99 30 0.303 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 GO:0002250 Not Cancer Driver No 69 0.272 0 0 0.0 1
FCRL4 FCRL4 Q96PJ5 Fc receptor-like protein 4 chr1 GO:0002250 Census Yes 147 0.285 174 57 0.328 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0002250 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0002250 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGL1_ENST00000381840 FGL1 Q08830 Fibrinogen-like protein 1 chr8 GO:0002250 Not Cancer Driver No 42 0.135 10 2 0.2 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0002250 Not Cancer Driver No 92 0.171 70 13 0.186 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0002250 Census, Compendium Yes 111 0.251 364 87 0.239 2
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0002250 Not Cancer Driver No 53 0.147 25 3 0.12 0
GZMM GZMM P51124 Granzyme M chr19 GO:0002250 Not Cancer Driver No 25 0.097 12 1 0.083 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0002250 Not Cancer Driver No 69 0.229 17 2 0.118 3
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0002250 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0002250 Compendium Yes 78 0.215 169 34 0.201 0
HLA-C HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 GO:0002250 Not Cancer Driver No 104 0.284 175 58 0.331 0
HLA-DMA HLA-DMA P28067 HLA class II histocompatibility antigen, DM alpha chain chr6 GO:0002250 Not Cancer Driver No 27 0.103 16 2 0.125 0
HLA-DMB HLA-DMB P28068 HLA class II histocompatibility antigen, DM beta chain chr6 GO:0002250 Not Cancer Driver No 41 0.156 41 9 0.22 0
HLA-DOA HLA-DOA P06340 HLA class II histocompatibility antigen, DO alpha chain chr6 GO:0002250 Not Cancer Driver No 39 0.156 7 1 0.143 0
HLA-DOB HLA-DOB P13765 HLA class II histocompatibility antigen, DO beta chain chr6 GO:0002250 Not Cancer Driver No 34 0.125 9 2 0.222 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 GO:0002250 Not Cancer Driver No 37 0.142 30 4 0.133 0
HLA-DPB1 HLA-DPB1 P04440 HLA class II histocompatibility antigen, DP beta 1 chain chr6 GO:0002250 Not Cancer Driver No 38 0.147 39 4 0.103 0
HLA-DQA2 HLA-DQA2 P01906 HLA class II histocompatibility antigen, DQ alpha 2 chain chr6 GO:0002250 Not Cancer Driver No 61 0.239 7 0 0.0 0
HLA-DQB2 HLA-DQB2 P05538 HLA class II histocompatibility antigen, DQ beta 2 chain chr6 GO:0002250 Not Cancer Driver No 55 0.205 38 5 0.132 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0002250 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0002250 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-DRB5 HLA-DRB5 Q30154 HLA class II histocompatibility antigen, DR beta 5 chain chr6 GO:0002250 Not Cancer Driver No 35 0.132 18 2 0.111 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0002250 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0002250 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMHB1 HMHB1 O97980 Minor histocompatibility protein HB-1 chr5 GO:0002250 Not Cancer Driver No 3 0.073 10 0 0.0 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0002250 Not Cancer Driver No 22 0.101 3 0 0.0 62
HRAS HRAS P01112 GTPase HRas chr11 GO:0002250 Census, Compendium Yes 107 0.566 16 4 0.25 18
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0002250 Not Cancer Driver No 25 0.083 30 2 0.067 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0002250 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0002250 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0002250 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0002250 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0002250 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0002250 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0002250 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0002250 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0002250 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0002250 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0002250 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0002250 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0002250 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0002250 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0002250 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0002250 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0002250 Not Cancer Driver No 32 0.164 10 3 0.3 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0002250 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX GO:0002250 Not Cancer Driver No 69 0.182 0 0 0.0 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0002250 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0002250 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL17RA IL17RA Q96F46 Interleukin-17 receptor A chr22 GO:0002250 Not Cancer Driver No 92 0.106 301 20 0.066 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0002250 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18BP_ENST00000337131 IL18BP O95998 Interleukin-18-binding protein chr11 GO:0002250 Not Cancer Driver No 16 0.082 50 6 0.12 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0002250 Census Yes 24 0.157 6 1 0.167 0
IL21R_ENST00000395754 IL21R Q9HBE5 Interleukin-21 receptor chr16 GO:0002250 Census Yes 133 0.247 183 47 0.257 1
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0002250 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0002250 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL9 IL9 P15248 Interleukin-9 chr5 GO:0002250 Not Cancer Driver No 12 0.083 4 0 0.0 0
IL9R IL9R Q01113 Interleukin-9 receptor chrX GO:0002250 Not Cancer Driver No 96 0.184 78 18 0.231 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0002250 Not Cancer Driver No 176 0.148 578 90 0.156 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0002250 Not Cancer Driver No 43 0.085 253 19 0.075 1
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0002250 Census Yes 139 0.224 43 10 0.233 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0002250 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0002250 Census, Compendium Yes 167 0.149 63 10 0.159 7
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0002250 Not Cancer Driver No 50 0.161 62 11 0.177 2
JCHAIN JCHAIN P01591 Immunoglobulin J chain chr4 GO:0002250 Not Cancer Driver No 37 0.233 9 3 0.333 0
KLHL6 KLHL6 Q8WZ60 Kelch-like protein 6 chr3 GO:0002250 Compendium Yes 149 0.24 25 7 0.28 0
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0002250 Not Cancer Driver No 49 0.21 49 10 0.204 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0002250 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0002250 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0002250 Not Cancer Driver No 38 0.176 0 0 0.0 0
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0002250 Not Cancer Driver No 47 0.09 208 11 0.053 0
LAIR1 LAIR1 Q6GTX8 Leukocyte-associated immunoglobulin-like receptor 1 chr19 GO:0002250 Not Cancer Driver No 65 0.226 179 43 0.24 0
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 GO:0002250 Not Cancer Driver No 67 0.161 222 38 0.171 0
LAT2 LAT2 Q9GZY6 Linker for activation of T-cells family member 2 chr7 GO:0002250 Not Cancer Driver No 39 0.16 176 29 0.165 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0002250 Not Cancer Driver No 37 0.141 213 29 0.136 0
LAX1 LAX1 Q8IWV1 Lymphocyte transmembrane adapter 1 chr1 GO:0002250 Not Cancer Driver No 61 0.153 228 32 0.14 0
LILRA1 LILRA1 O75019 Leukocyte immunoglobulin-like receptor subfamily A member 1 chr19 GO:0002250 Not Cancer Driver No 162 0.331 78 26 0.333 0
LILRA6 LILRA6 Q6PI73 Leukocyte immunoglobulin-like receptor subfamily A member 6 chr19 GO:0002250 Not Cancer Driver No 134 0.279 162 41 0.253 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0002250 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0002250 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0002250 Not Cancer Driver No 162 0.362 277 115 0.415 0
LILRB5_ENST00000316219 LILRB5 O75023 Leukocyte immunoglobulin-like receptor subfamily B member 5 chr19 GO:0002250 Not Cancer Driver No 157 0.266 202 73 0.361 0
LIME1 LIME1 Q9H400 Lck-interacting transmembrane adapter 1 chr20 GO:0002250 Not Cancer Driver No 22 0.075 193 17 0.088 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0002250 Census Yes 95 0.186 84 12 0.143 0
MARCH8_ENST00000319836 MARCHF8 Q5T0T0 E3 ubiquitin-protein ligase MARCHF8 chr10 GO:0002250 Not Cancer Driver No 31 0.107 71 8 0.113 0
MCOLN1 MCOLN1 Q9GZU1 Mucolipin-1 chr19 GO:0002250 Not Cancer Driver No 77 0.133 63 15 0.238 7
MCOLN2 MCOLN2 Q8IZK6 Mucolipin-2 chr1 GO:0002250 Not Cancer Driver No 93 0.164 0 0 0.0 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0002250 Not Cancer Driver No 92 0.195 408 81 0.199 0
MICB MICB Q29980 MHC class I polypeptide-related sequence B chr6 GO:0002250 Not Cancer Driver No 56 0.146 175 22 0.126 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0002250 Census Yes 92 0.099 37 4 0.108 70
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0002250 Census, Compendium Yes 37 0.125 47 1 0.021 2
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 GO:0002250 Census, Compendium Yes 86 0.096 510 46 0.09 0
NLRP10 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 GO:0002250 Not Cancer Driver No 201 0.307 96 34 0.354 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0002250 Census, Compendium Yes 363 0.142 686 87 0.127 3
ORAI1 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 GO:0002250 Not Cancer Driver No 26 0.086 101 9 0.089 5
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 GO:0002250 Not Cancer Driver No 31 0.114 33 2 0.061 0
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 GO:0002250 Not Cancer Driver No 124 0.147 537 87 0.162 0
PAG1 PAG1 Q9NWQ8 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 chr8 GO:0002250 Not Cancer Driver No 58 0.134 394 54 0.137 0
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 GO:0002250 Not Cancer Driver No 56 0.194 141 37 0.262 0
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0002250 Census, Compendium Yes 33 0.121 41 13 0.317 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0002250 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0002250 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0002250 Not Cancer Driver No 318 0.289 121 39 0.322 0
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0002250 Census, Compendium Yes 145 0.176 337 66 0.196 0
PRF1_ENST00000373209 PRF1 P14222 Perforin-1 chr10 GO:0002250 Census, Compendium Yes 122 0.22 145 36 0.248 8
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0002250 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0002250 Compendium Yes 79 0.117 43 9 0.209 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0002250 Compendium Yes 118 0.134 246 34 0.138 0
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0002250 Not Cancer Driver No 10 0.036 199 6 0.03 0
PSG9 PSG9 Q00887 Pregnancy-specific beta-1-glycoprotein 9 chr19 GO:0002250 Not Cancer Driver No 125 0.293 40 8 0.2 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0002250 Not Cancer Driver No 161 0.16 261 37 0.142 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0002250 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAP1GAP2 RAP1GAP2 Q684P5 Rap1 GTPase-activating protein 2 chr17 GO:0002250 Not Cancer Driver No 93 0.127 413 57 0.138 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0002250 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0002250 Not Cancer Driver No 97 0.105 197 19 0.096 0
RAPGEF4 RAPGEF4 Q8WZA2 Rap guanine nucleotide exchange factor 4 chr2 GO:0002250 Not Cancer Driver No 149 0.147 191 29 0.152 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0002250 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0002250 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 GO:0002250 Not Cancer Driver No 58 0.079 344 24 0.07 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX GO:0002250 Not Cancer Driver No 40 0.312 24 8 0.333 19
SH2D1B SH2D1B O14796 SH2 domain-containing protein 1B chr1 GO:0002250 Not Cancer Driver No 34 0.258 0 0 0.0 0
SIGLEC10 SIGLEC10 Q96LC7 Sialic acid-binding Ig-like lectin 10 chr19 GO:0002250 Not Cancer Driver No 172 0.247 310 82 0.265 0
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0002250 Not Cancer Driver No 67 0.064 666 43 0.065 0
SIT1 SIT1 Q9Y3P8 Signaling threshold-regulating transmembrane adapter 1 chr9 GO:0002250 Not Cancer Driver No 21 0.107 122 9 0.074 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 GO:0002250 Not Cancer Driver No 67 0.187 130 27 0.208 0
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:0002250 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0002250 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF7 SLAMF7 Q9NQ25 SLAM family member 7 chr1 GO:0002250 Not Cancer Driver No 66 0.197 53 14 0.264 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0002250 Census, Compendium Yes 110 0.143 152 15 0.099 19
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0002250 Census Yes 96 0.151 131 27 0.206 5
TAP2 TAP2 Q03519 Antigen peptide transporter 2 chr6 GO:0002250 Not Cancer Driver No 71 0.103 20 1 0.05 0
TARM1_ENST00000432826 TARM1 B6A8C7 T-cell-interacting, activating receptor on myeloid cells protein 1 chr19 GO:0002250 Not Cancer Driver No 13 0.048 21 1 0.048 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0002250 Compendium Yes 68 0.082 102 6 0.059 5
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 GO:0002250 Census, Compendium Yes 91 0.144 57 15 0.263 0
TFE3 TFE3 P19532 Transcription factor E3 chrX GO:0002250 Census Yes 92 0.16 524 84 0.16 0
TFEB_ENST00000403298 TFEB P19484 Transcription factor EB chr6 GO:0002250 Census Yes 58 0.122 429 47 0.11 0
THEMIS_ENST00000368250 THEMIS Q8N1K5 Protein THEMIS chr6 GO:0002250 Not Cancer Driver No 208 0.324 111 34 0.306 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0002250 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR8_ENST00000218032 TLR8 Q9NR97 Toll-like receptor 8 chrX GO:0002250 Not Cancer Driver No 180 0.173 30 7 0.233 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0002250 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFRSF13B TNFRSF13B O14836 Tumor necrosis factor receptor superfamily member 13B chr17 GO:0002250 Not Cancer Driver No 60 0.205 108 25 0.231 0
TNFRSF13C TNFRSF13C Q96RJ3 Tumor necrosis factor receptor superfamily member 13C chr22 GO:0002250 Not Cancer Driver No 17 0.092 128 15 0.117 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0002250 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF17 TNFRSF17 Q02223 Tumor necrosis factor receptor superfamily member 17 chr16 GO:0002250 Census Yes 28 0.152 1 0 0.0 0
TNFRSF21 TNFRSF21 O75509 Tumor necrosis factor receptor superfamily member 21 chr6 GO:0002250 Not Cancer Driver No 98 0.15 280 46 0.164 0
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0002250 Not Cancer Driver No 59 0.103 410 39 0.095 2
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0002250 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0002250 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM1 TREM1 Q9NP99 Triggering receptor expressed on myeloid cells 1 chr6 GO:0002250 Not Cancer Driver No 45 0.192 63 7 0.111 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0002250 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0002250 Not Cancer Driver No 152 0.125 149 18 0.121 12
TSC1 TSC1 Q92574 Hamartin chr9 GO:0002250 Census, Compendium Yes 135 0.116 732 78 0.107 11
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0002250 Not Cancer Driver No 87 0.165 61 9 0.148 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0002250 Not Cancer Driver No 120 0.11 248 30 0.121 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 GO:0002250 Not Cancer Driver No 57 0.095 127 5 0.039 0
VTCN1 VTCN1 Q7Z7D3 V-set domain-containing T-cell activation inhibitor 1 chr1 GO:0002250 Not Cancer Driver No 43 0.152 3 2 0.667 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0002250 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZNF683 ZNF683 Q8IZ20 Tissue-resident T-cell transcription regulator protein ZNF683 chr1 GO:0002250 Not Cancer Driver No 103 0.197 202 32 0.158 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0002250 Not Cancer Driver No 55 0.13 56 11 0.196 1