Total number of protein in "GO:0002028" GO term: 84
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | GO:0002028 | Not Cancer Driver | No | 131 | 0.144 | 244 | 42 | 0.172 | 8 |
| ADRB2 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | GO:0002028 | Not Cancer Driver | No | 52 | 0.126 | 35 | 4 | 0.114 | 0 |
| AHCYL1 | AHCYL1 | O43865 | S-adenosylhomocysteine hydrolase-like protein 1 | chr1 | GO:0002028 | Not Cancer Driver | No | 58 | 0.109 | 108 | 10 | 0.093 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0002028 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ANK3 | ANK3 | Q12955 | Ankyrin-3 | chr10 | GO:0002028 | Not Cancer Driver | No | 860 | 0.196 | 3054 | 579 | 0.19 | 0 |
| ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | GO:0002028 | Census | Yes | 115 | 0.112 | 115 | 16 | 0.139 | 6 |
| ATP1A2 | ATP1A2 | P50993 | Sodium/potassium-transporting ATPase subunit alpha-2 | chr1 | GO:0002028 | Not Cancer Driver | No | 230 | 0.225 | 161 | 34 | 0.211 | 8 |
| ATP1B1 | ATP1B1 | P05026 | Sodium/potassium-transporting ATPase subunit beta-1 | chr1 | GO:0002028 | Not Cancer Driver | No | 38 | 0.125 | 55 | 9 | 0.164 | 0 |
| ATP1B2 | ATP1B2 | P14415 | Sodium/potassium-transporting ATPase subunit beta-2 | chr17 | GO:0002028 | Not Cancer Driver | No | 40 | 0.138 | 16 | 6 | 0.375 | 0 |
| ATP1B3 | ATP1B3 | P54709 | Sodium/potassium-transporting ATPase subunit beta-3 | chr3 | GO:0002028 | Not Cancer Driver | No | 36 | 0.129 | 6 | 1 | 0.167 | 0 |
| BPIFA1_ENST00000375413 | BPIFA1 | Q9NP55 | BPI fold-containing family A member 1 | chr20 | GO:0002028 | Not Cancer Driver | No | 54 | 0.211 | 0 | 0 | 0.0 | 0 |
| CAMK2D_ENST00000342666 | CAMK2D | Q13557 | Calcium/calmodulin-dependent protein kinase type II subunit delta | chr4 | GO:0002028 | Not Cancer Driver | No | 57 | 0.114 | 84 | 10 | 0.119 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0002028 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CHP1 | CHP1 | Q99653 | Calcineurin B homologous protein 1 | chr15 | GO:0002028 | Not Cancer Driver | No | 27 | 0.138 | 70 | 12 | 0.171 | 0 |
| CNKSR3 | CNKSR3 | Q6P9H4 | Connector enhancer of kinase suppressor of ras 3 | chr6 | GO:0002028 | Not Cancer Driver | No | 72 | 0.13 | 269 | 43 | 0.16 | 0 |
| CNTN1 | CNTN1 | Q12860 | Contactin-1 | chr12 | GO:0002028 | Not Cancer Driver | No | 265 | 0.26 | 220 | 50 | 0.227 | 0 |
| COMMD1 | COMMD1 | Q8N668 | COMM domain-containing protein 1 | chr2 | GO:0002028 | Not Cancer Driver | No | 21 | 0.111 | 17 | 0 | 0.0 | 0 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | GO:0002028 | Not Cancer Driver | No | 120 | 0.133 | 460 | 67 | 0.146 | 0 |
| DMD | DMD | P11532 | Dystrophin | chrX | GO:0002028 | Not Cancer Driver | No | 895 | 0.243 | 1399 | 329 | 0.235 | 14 |
| DMPK_ENST00000291270 | DMPK | Q09013 | Myotonin-protein kinase | chr19 | GO:0002028 | Not Cancer Driver | No | 54 | 0.086 | 220 | 14 | 0.064 | 0 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | GO:0002028 | Census | Yes | 138 | 0.159 | 270 | 43 | 0.159 | 22 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0002028 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0002028 | Not Cancer Driver | No | 88 | 0.22 | 45 | 17 | 0.378 | 0 |
| DRD4 | DRD4 | P21917 | D(4) dopamine receptor | chr11 | GO:0002028 | Not Cancer Driver | No | 26 | 0.062 | 109 | 0 | 0.0 | 0 |
| FGF11 | FGF11 | Q92914 | Fibroblast growth factor 11 | chr17 | GO:0002028 | Not Cancer Driver | No | 20 | 0.089 | 68 | 5 | 0.074 | 0 |
| FGF12 | FGF12 | P61328 | Fibroblast growth factor 12 | chr3 | GO:0002028 | Not Cancer Driver | No | 74 | 0.305 | 102 | 30 | 0.294 | 1 |
| FGF13_ENST00000315930 | FGF13 | Q92913 | Fibroblast growth factor 13 | chrX | GO:0002028 | Not Cancer Driver | No | 70 | 0.286 | 96 | 33 | 0.344 | 2 |
| FGF14_ENST00000376143 | FGF14 | Q92915 | Fibroblast growth factor 14 | chr13 | GO:0002028 | Not Cancer Driver | No | 72 | 0.291 | 93 | 30 | 0.323 | 1 |
| FXYD1_ENST00000455515 | FXYD1 | O00168 | Phospholemman | chr19 | GO:0002028 | Not Cancer Driver | No | 10 | 0.109 | 22 | 4 | 0.182 | 0 |
| FXYD2 | FXYD2 | P54710 | Sodium/potassium-transporting ATPase subunit gamma | chr11 | GO:0002028 | Not Cancer Driver | No | 2 | 0.03 | 20 | 2 | 0.1 | 1 |
| FXYD3_ENST00000604404 | FXYD3 | Q14802 | FXYD domain-containing ion transport regulator 3 | chr19 | GO:0002028 | Not Cancer Driver | No | 16 | 0.184 | 16 | 1 | 0.062 | 0 |
| FXYD4_ENST00000476166 | FXYD4 | P59646 | FXYD domain-containing ion transport regulator 4 | chr10 | GO:0002028 | Not Cancer Driver | No | 9 | 0.101 | 5 | 1 | 0.2 | 0 |
| FXYD5_ENST00000590686 | FXYD5 | Q96DB9 | FXYD domain-containing ion transport regulator 5 | chr19 | GO:0002028 | Not Cancer Driver | No | 31 | 0.174 | 136 | 18 | 0.132 | 0 |
| FXYD6_ENST00000260282 | FXYD6 | Q9H0Q3 | FXYD domain-containing ion transport regulator 6 | chr11 | GO:0002028 | Not Cancer Driver | No | 14 | 0.147 | 27 | 4 | 0.148 | 0 |
| FXYD7 | FXYD7 | P58549 | FXYD domain-containing ion transport regulator 7 | chr19 | GO:0002028 | Not Cancer Driver | No | 7 | 0.087 | 43 | 2 | 0.047 | 0 |
| GLRX_ENST00000505427 | GLRX | P35754 | Glutaredoxin-1 | chr5 | GO:0002028 | Not Cancer Driver | No | 14 | 0.132 | 0 | 0 | 0.0 | 0 |
| GPD1L | GPD1L | Q8N335 | Glycerol-3-phosphate dehydrogenase 1-like protein | chr3 | GO:0002028 | Not Cancer Driver | No | 40 | 0.114 | 13 | 1 | 0.077 | 0 |
| HECW1 | HECW1 | Q76N89 | E3 ubiquitin-protein ligase HECW1 | chr7 | GO:0002028 | Not Cancer Driver | No | 420 | 0.262 | 748 | 191 | 0.255 | 0 |
| HECW2_ENST00000644256 | HECW2 | Q9P2P5 | E3 ubiquitin-protein ligase HECW2 | chr2 | GO:0002028 | Not Cancer Driver | No | 348 | 0.221 | 845 | 195 | 0.231 | 4 |
| KCNQ1 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0002028 | Not Cancer Driver | No | 78 | 0.115 | 219 | 20 | 0.091 | 132 |
| KLHL24_ENST00000242810 | KLHL24 | Q6TFL4 | Kelch-like protein 24 | chr3 | GO:0002028 | Not Cancer Driver | No | 102 | 0.17 | 17 | 6 | 0.353 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0002028 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| NEDD4L | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | GO:0002028 | Not Cancer Driver | No | 126 | 0.129 | 463 | 60 | 0.13 | 4 |
| NETO1 | NETO1 | Q8TDF5 | Neuropilin and tolloid-like protein 1 | chr18 | GO:0002028 | Not Cancer Driver | No | 186 | 0.349 | 103 | 33 | 0.32 | 0 |
| NETO2 | NETO2 | Q8NC67 | Neuropilin and tolloid-like protein 2 | chr16 | GO:0002028 | Not Cancer Driver | No | 71 | 0.135 | 102 | 22 | 0.216 | 0 |
| NKAIN1 | NKAIN1 | Q4KMZ8 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 | chr1 | GO:0002028 | Not Cancer Driver | No | 20 | 0.097 | 0 | 0 | 0.0 | 0 |
| NKAIN2 | NKAIN2 | Q5VXU1 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 | chr6 | GO:0002028 | Not Cancer Driver | No | 44 | 0.212 | 0 | 0 | 0.0 | 0 |
| NKAIN3 | NKAIN3 | Q8N8D7 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 | chr8 | GO:0002028 | Not Cancer Driver | No | 58 | 0.294 | 0 | 0 | 0.0 | 0 |
| NKAIN4 | NKAIN4 | Q8IVV8 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 | chr20 | GO:0002028 | Not Cancer Driver | No | 21 | 0.101 | 0 | 0 | 0.0 | 0 |
| NKX2-5 | NKX2-5 | P52952 | Homeobox protein Nkx-2.5 | chr5 | GO:0002028 | Not Cancer Driver | No | 48 | 0.148 | 181 | 22 | 0.122 | 55 |
| NOS1_ENST00000317775 | NOS1 | P29475 | Nitric oxide synthase, brain | chr12 | GO:0002028 | Not Cancer Driver | No | 405 | 0.282 | 342 | 99 | 0.289 | 0 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0002028 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| OSR1 | OSR1 | Q8TAX0 | Protein odd-skipped-related 1 | chr2 | GO:0002028 | Not Cancer Driver | No | 57 | 0.214 | 67 | 17 | 0.254 | 0 |
| P2RX4_ENST00000337233 | P2RX4 | Q99571 | P2X purinoceptor 4 | chr12 | GO:0002028 | Not Cancer Driver | No | 36 | 0.093 | 0 | 0 | 0.0 | 0 |
| P2RX7 | P2RX7 | Q99572 | P2X purinoceptor 7 | chr12 | GO:0002028 | Not Cancer Driver | No | 51 | 0.086 | 14 | 2 | 0.143 | 0 |
| PCSK9 | PCSK9 | Q8NBP7 | Proprotein convertase subtilisin/kexin type 9 | chr1 | GO:0002028 | Not Cancer Driver | No | 86 | 0.124 | 148 | 27 | 0.182 | 9 |
| PER1 | PER1 | O15534 | Period circadian protein homolog 1 | chr17 | GO:0002028 | Census | Yes | 160 | 0.124 | 948 | 116 | 0.122 | 0 |
| PKP2 | PKP2 | Q99959 | Plakophilin-2 | chr12 | GO:0002028 | Not Cancer Driver | No | 176 | 0.2 | 434 | 98 | 0.226 | 8 |
| PRKCE | PRKCE | Q02156 | Protein kinase C epsilon type | chr2 | GO:0002028 | Not Cancer Driver | No | 107 | 0.145 | 170 | 26 | 0.153 | 0 |
| PRSS8 | PRSS8 | Q16651 | Prostasin | chr16 | GO:0002028 | Not Cancer Driver | No | 30 | 0.087 | 27 | 3 | 0.111 | 0 |
| PTPN3 | PTPN3 | P26045 | Tyrosine-protein phosphatase non-receptor type 3 | chr9 | GO:0002028 | Not Cancer Driver | No | 139 | 0.152 | 214 | 28 | 0.131 | 0 |
| RANGRF | RANGRF | Q9HD47 | Ran guanine nucleotide release factor | chr17 | GO:0002028 | Not Cancer Driver | No | 10 | 0.054 | 42 | 5 | 0.119 | 0 |
| SCN1B_ENST00000262631 | SCN1B | Q07699 | Sodium channel subunit beta-1 | chr19 | GO:0002028 | Not Cancer Driver | No | 35 | 0.161 | 4 | 1 | 0.25 | 5 |
| SCN2B | SCN2B | O60939 | Sodium channel subunit beta-2 | chr11 | GO:0002028 | Not Cancer Driver | No | 46 | 0.214 | 52 | 7 | 0.135 | 2 |
| SCN3B_ENST00000299333 | SCN3B | Q9NY72 | Sodium channel subunit beta-3 | chr11 | GO:0002028 | Not Cancer Driver | No | 63 | 0.293 | 16 | 5 | 0.312 | 3 |
| SCN4B | SCN4B | Q8IWT1 | Sodium channel subunit beta-4 | chr11 | GO:0002028 | Not Cancer Driver | No | 23 | 0.101 | 46 | 4 | 0.087 | 3 |
| SCN5A_ENST00000333535 | SCN5A | Q14524 | Sodium channel protein type 5 subunit alpha | chr3 | GO:0002028 | Not Cancer Driver | No | 491 | 0.244 | 550 | 144 | 0.262 | 190 |
| SERPINE2_ENST00000258405 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0002028 | Not Cancer Driver | No | 62 | 0.156 | 0 | 0 | 0.0 | 0 |
| SIK1 | SIK1 | P57059 | Serine/threonine-protein kinase SIK1 | chr21 | GO:0002028 | Not Cancer Driver | No | 80 | 0.102 | 330 | 30 | 0.091 | 3 |
| SLC8A1_ENST00000332839 | SLC8A1 | P32418 | Sodium/calcium exchanger 1 | chr2 | GO:0002028 | Not Cancer Driver | No | 305 | 0.313 | 158 | 48 | 0.304 | 0 |
| SLC9A1 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0002028 | Not Cancer Driver | No | 89 | 0.109 | 251 | 29 | 0.116 | 1 |
| SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0002028 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
| SLMAP | SLMAP | Q14BN4 | Sarcolemmal membrane-associated protein | chr3 | GO:0002028 | Not Cancer Driver | No | 77 | 0.093 | 464 | 38 | 0.082 | 0 |
| SNTA1 | SNTA1 | Q13424 | Alpha-1-syntrophin | chr20 | GO:0002028 | Not Cancer Driver | No | 43 | 0.085 | 238 | 14 | 0.059 | 2 |
| SPTBN4_ENST00000598249 | SPTBN4 | Q9H254 | Spectrin beta chain, non-erythrocytic 4 | chr19 | GO:0002028 | Not Cancer Driver | No | 312 | 0.122 | 866 | 103 | 0.119 | 0 |
| STK39 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0002028 | Not Cancer Driver | No | 64 | 0.117 | 182 | 19 | 0.104 | 0 |
| STOM | STOM | P27105 | Stomatin | chr9 | GO:0002028 | Not Cancer Driver | No | 23 | 0.08 | 44 | 3 | 0.068 | 0 |
| TESC | TESC | Q96BS2 | Calcineurin B homologous protein 3 | chr12 | GO:0002028 | Not Cancer Driver | No | 31 | 0.145 | 73 | 6 | 0.082 | 0 |
| UTRN | UTRN | P46939 | Utrophin | chr6 | GO:0002028 | Not Cancer Driver | No | 476 | 0.139 | 1283 | 183 | 0.143 | 0 |
| WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | GO:0002028 | Not Cancer Driver | No | 278 | 0.117 | 1959 | 223 | 0.114 | 0 |
| WNK2 | WNK2 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | chr9 | GO:0002028 | Census, Compendium | Yes | 223 | 0.097 | 1868 | 167 | 0.089 | 0 |
| WNK3_ENST00000375159 | WNK3 | Q9BYP7 | Serine/threonine-protein kinase WNK3 | chrX | GO:0002028 | Not Cancer Driver | No | 281 | 0.156 | 1281 | 200 | 0.156 | 0 |
| WNK4 | WNK4 | Q96J92 | Serine/threonine-protein kinase WNK4 | chr17 | GO:0002028 | Compendium | Yes | 178 | 0.143 | 916 | 126 | 0.138 | 4 |
| YWHAH | YWHAH | Q04917 | 14-3-3 protein eta | chr22 | GO:0002028 | Not Cancer Driver | No | 15 | 0.061 | 55 | 3 | 0.055 | 0 |